Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainSH3

RUSC1 MAPK8IP1 DLG2 MYO15A CASKIN2 VAV2

8.27e-06216426PS50002
DomainSH3

RUSC1 MAPK8IP1 DLG2 MYO15A CASKIN2 VAV2

8.27e-06216426SM00326
DomainSH3_domain

RUSC1 MAPK8IP1 DLG2 MYO15A CASKIN2 VAV2

9.19e-06220426IPR001452
DomainSH3_2

DLG2 MYO15A CASKIN2 VAV2

4.10e-0586424IPR011511
DomainSH3_2

DLG2 MYO15A CASKIN2 VAV2

4.10e-0586424PF07653
DomainMYTH4

ARHGAP39 MYO15A

1.76e-049422PS51016
DomainMyTH4_dom

ARHGAP39 MYO15A

1.76e-049422IPR000857
DomainMyTH4

ARHGAP39 MYO15A

1.76e-049422SM00139
DomainMyTH4

ARHGAP39 MYO15A

1.76e-049422PF00784
DomainSH3_1

RUSC1 MAPK8IP1 DLG2 VAV2

4.95e-04164424PF00018
Domain-

NAV2 CEP95 VAV2

5.43e-04714231.10.418.10
DomainCH-domain

NAV2 CEP95 VAV2

6.38e-0475423IPR001715
DomainSemaphorin

SEMA6A SEMA6D

9.14e-0420422IPR027231
DomainSEMA

SEMA6A SEMA6D

2.20e-0331422PS51004
DomainSema

SEMA6A SEMA6D

2.20e-0331422SM00630
DomainSemap_dom

SEMA6A SEMA6D

2.20e-0331422IPR001627
DomainSema

SEMA6A SEMA6D

2.20e-0331422PF01403
DomainPlexin_repeat

SEMA6A SEMA6D

2.35e-0332422IPR002165
DomainPSI

SEMA6A SEMA6D

2.35e-0332422PF01437
DomainPSI

SEMA6A SEMA6D

4.40e-0344422IPR016201
DomainPSI

SEMA6A SEMA6D

4.80e-0346422SM00423
Domain-

NAV2 NAV1 DLG2 MSH4 MYO15A DHX38

6.12e-037464263.40.50.300
DomainVWA

VWA3A COL12A1

7.04e-0356422PF00092
DomainCH

NAV2 VAV2

9.39e-0365422SM00033
DomainRhoGEF

ARHGEF33 VAV2

1.02e-0268422SM00325
DomainSAM_1

MAP3K20 CASKIN2

1.02e-0268422PF00536
DomainDH_2

ARHGEF33 VAV2

1.08e-0270422PS50010
DomainRhoGEF

ARHGEF33 VAV2

1.08e-0270422PF00621
DomainCH

NAV2 VAV2

1.08e-0270422PF00307
DomainDH-domain

ARHGEF33 VAV2

1.11e-0271422IPR000219
Domain-

ARHGEF33 VAV2

1.11e-02714221.20.900.10
DomainP-loop_NTPase

NAV2 NAV1 DLG2 MSH4 MYO15A DHX38

1.12e-02848426IPR027417
Domain-

MAPK8IP1 VAV2 PHLDB2 VEPH1

1.13e-023914242.30.29.30
DomainCH

NAV2 VAV2

1.17e-0273422PS50021
Domain-

VWA3A COL12A1

1.20e-02744223.40.50.410
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MAP3K20 NAV2 NAV1 FSIP2 RBM15 CASKIN2 EXPH5 CEP95 PHLDB2

1.34e-0686145936931259
Pubmed

Shear stress-regulated miR-27b controls pericyte recruitment by repressing SEMA6A and SEMA6D.

SEMA6A SEMA6D

4.91e-06345228453731
Pubmed

Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms.

NAV2 NAV1

4.91e-06345212062803
Pubmed

Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans.

NAV2 NAV1

4.91e-06345212079279
Pubmed

Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53.

NAV2 NAV1

4.91e-06345215158073
Pubmed

PIP3-Phldb2 is crucial for LTP regulating synaptic NMDA and AMPA receptor density and PSD95 turnover.

DLG2 PHLDB2

2.45e-05645230867511
Pubmed

Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension.

NAV2 NAV1

3.42e-05745225065758
Pubmed

Genome-wide association analysis of eating disorder-related symptoms, behaviors, and personality traits.

SEMA6D TRPS1

5.86e-05945222911880
Pubmed

A Protein Scaffold Coordinates SRC-Mediated JNK Activation in Response to Metabolic Stress.

MAPK8IP1 VAV2

7.32e-051045228930674
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

NAV2 NAV1 SEMA6A CASKIN2 EXPH5 PHLDB2

8.85e-0556945630639242
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

NAV1 ZNF318 NBR1 PHLDB2

9.54e-0518445432908313
Pubmed

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

NAV1 RBM15 ZNF318 SRSF7 MYPN

1.02e-0436145530344098
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

MAP3K20 RBM15 SRSF7 CEP95 PHLDB2

1.02e-0436145526167880
Pubmed

On and off retinal circuit assembly by divergent molecular mechanisms.

SEMA6A SEMA6D

1.07e-041245224179230
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

KCTD12 RBM15 ARHGAP39 C5orf24 ECH1 VAV2 VDAC3

1.63e-0491645732203420
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

MAP3K20 NAV1 RBM15 SRSF7 EXPH5 PHLDB2 DHX38 VDAC3

1.87e-04125745836526897
Pubmed

Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.

SEMA6A SEMA6D

1.94e-041645222632726
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

NAV1 RUSC1 ZNF318 ZNF280D TRPS1

2.01e-0441845534709266
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NAV1 KCTD12 MAPK8IP1 DLG2 ZNF318 ARHGAP39 PHLDB2

2.21e-0496345728671696
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

MAP3K20 NAV1 RBM15 ECH1 PHLDB2

2.72e-0444645524255178
Pubmed

Recruitment of the human TREX complex to mRNA during splicing.

RBM15 SRSF7

3.06e-042045215998806
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

ZNF318 CASKIN2 NBR1 EXPH5

3.73e-0426345434702444
Pubmed

Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.

SRSF7 CASKIN2 PHLDB2

3.76e-0410845319531213
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MIER2 KCTD12 ARHGAP39 EXPH5 DHX38

4.29e-0449345515368895
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

MAP3K20 NAV2 RBM15 PHLDB2 MYPN

4.70e-0450345516964243
Pubmed

Laser capture microdissection and cDNA array analysis for identification of mouse KIAA/FLJ genes differentially expressed in the embryonic dorsal spinal cord.

NAV2 ARHGAP39

5.63e-042745219026994
Pubmed

Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.

SEMA6A SEMA6D

6.06e-042845218617019
Pubmed

Genetic mapping of eight SH3 domain genes on seven mouse chromosomes.

VAV2 GABRA1

6.06e-042845210087302
Pubmed

Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.

DLG2 CEP95 MYPN

7.05e-0413445324324551
Pubmed

Lhx2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth.

FREM1 TRPS1

8.43e-043345226952977
Pubmed

Sema6D acts downstream of bone morphogenetic protein signalling to promote atrioventricular cushion development in mice.

SEMA6A SEMA6D

9.48e-043545228172500
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

KCTD12 DLG2 ARHGAP39 GABRA1

1.05e-0334745417114649
Pubmed

Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development.

SRSF7 TRPS1

1.12e-033845229799838
Pubmed

ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.

RBM15 ZNF318 SRSF7 ECH1 VDAC3

1.24e-0362445533729478
Cytoband2p22.1

ARHGEF33 SRSF7

1.12e-04164522p22.1
GeneFamilyImmunoglobulin like domain containing|Semaphorins

SEMA6A SEMA6D

5.30e-0420312736
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

VAV2 PHLDB2 VEPH1

5.18e-03206313682
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF33 VAV2

5.70e-0366312722
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VWA3A COL12A1 EXPH5 VAV2 FREM1 TRPS1

1.85e-08169456716e9d4c5fb99c56b76afaa5ed90bfa859fde802
ToppCellnormal_Lung-Myeloid_cells-Undetermined|Myeloid_cells / Location, Cell class and cell subclass

VWA3A ARHGEF33 ARHGAP39 CASKIN2 EXPH5

6.00e-07161455283012858e575c70d09950de53da041509f59bfa
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL12A1 VAV2 FREM1 PHLDB2 TRPS1

1.10e-0618245572e65a23cd36085bc880087d3cae92395de918a1
ToppCellCOVID-19-lung-AT1|lung / Disease (COVID-19 only), tissue and cell type

NAV2 COL12A1 EXPH5 PHLDB2 VEPH1

1.13e-06183455942530449e9c6583705eeb8f6f12621daea57252
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MAP3K20 KCTD12 SEMA6A SEMA6D TRPS1

1.22e-061864557def03dd856b765bd3f493288641981c4f7fd26e
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NAV2 NAV1 COL12A1 FREM1 PHLDB2

1.75e-06200455b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NAV2 NAV1 COL12A1 FREM1 PHLDB2

1.75e-062004550c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA6A COL12A1 ARHGEF33 EXPH5

1.95e-05158454f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA6A COL12A1 ARHGEF33 EXPH5

1.95e-051584548c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-myeloid-myeloid_dendritic-dendritic_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MAP3K20 NAV1 KCTD12 FIGLA

2.26e-051644543088d5fa240d2f4a6e21281f7ac932aea2f9af49
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEMA6A COL12A1 PHLDB2 TRPS1

2.84e-05174454ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCellpdx-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

C17orf100 NBR1 VAV2 PHLDB2

2.97e-051764541e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCTD12 DLG2 PTGIR FREM1

3.25e-051804549b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL12A1 VAV2 FREM1 TRPS1

3.25e-05180454e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DLG2 VAV2 FREM1 VEPH1

3.32e-05181454aa233b652921848af2257cc3687a7a09c3acfb67
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL12A1 VAV2 PHLDB2 TRPS1

3.39e-0518245405c167158815bf25d509df59ab386e1990712765
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MAP3K20 NAV2 KCTD12 SEMA6D

3.46e-05183454e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

COL12A1 SEMA6D PHLDB2 VEPH1

3.46e-051834546821dca076318115d360ff426eb1218cfe104063
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

COL12A1 SEMA6D PHLDB2 VEPH1

3.54e-05184454561592edc3083fad41b91811151b442207c65dd9
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

NAV2 COL12A1 SEMA6D PHLDB2

3.61e-051854541c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellCOVID-19-Fibroblasts-Adventitial_FB|COVID-19 / group, cell type (main and fine annotations)

NAV2 DLG2 FREM1 PHLDB2

3.61e-05185454a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Kctd12-Inhibitory_Gad1Gad2Slc17a8_Htr3a.Ktcd12_(Interneuron,__GABA/Glutamate_co-releasing?_(candidate_CGE-derived_9))|Hippocampus / BrainAtlas - Mouse McCarroll V32

FSIP2 KCTD12 FREM1

3.73e-05644533e3eed30abcecd3fc8d30489dca05222ac353180
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Kctd12|Hippocampus / BrainAtlas - Mouse McCarroll V32

FSIP2 KCTD12 FREM1

3.73e-05644532edc3ae3e334bb04a411778e3b102b3a84a97824
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Kctd12-Inhibitory_Gad1Gad2Slc17a8_Htr3a.Ktcd12_(Interneuron,__GABA/Glutamate_co-releasing?_(candidate_CGE-derived_9))-|Hippocampus / BrainAtlas - Mouse McCarroll V32

FSIP2 KCTD12 FREM1

3.73e-0564453b8aac6e83c2e5b09b55ea22ddb29940099f186e1
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

VWA3A NAV2 SEMA6D TRPS1

3.77e-051874545258674d0346e5c51a4b965efcdc1790c970845d
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NAV2 COL12A1 PHLDB2 VEPH1

3.85e-05188454eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MAP3K20 NAV2 COL12A1 SEMA6D

3.85e-05188454f54b063025d80de631382bf5326bc40aab7f7d00
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL12A1 PTGIR FREM1 TRPS1

3.85e-05188454fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MAP3K20 NAV2 KCTD12 SEMA6D

3.85e-051884543004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

NAV2 SEMA6A EXPH5 FREM1

3.85e-05188454b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NAV2 SEMA6D EXPH5 FREM1

3.93e-051894547eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MAP3K20 NAV2 COL12A1 SEMA6D

3.93e-05189454da9ecc0d7b81c1901f30f97bb44112dc85444a66
ToppCellRA-14._Fibroblast_III|RA / Chamber and Cluster_Paper

NAV2 SEMA6A PHLDB2 TRPS1

3.93e-0518945446e9a58aacd79db5a02898a8c7244e1884adcfd1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NAV2 SEMA6D EXPH5 FREM1

3.93e-05189454975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NAV2 VAV2 FREM1 MYPN

4.26e-051934548b77625bf3c87d39767fb391d1beaca4ab02342b
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV1 SEMA6A SEMA6D PHLDB2

4.35e-05194454c8b9551b93a5aed62154b487db90130604a6125c
ToppCellLV-14._Fibroblast_III|LV / Chamber and Cluster_Paper

NAV2 SEMA6A PHLDB2 TRPS1

4.35e-05194454927c26aea0147f7a4b8fb3f192de4de263f1b978
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NAV2 NAV1 COL12A1 PTGIR

4.44e-051954543c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NAV2 DLG2 EXPH5 VEPH1

4.44e-051954549406866f99555198a9be311fbd65751b70f35446
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

COL12A1 PTGIR FREM1 TRPS1

4.44e-05195454f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL12A1 SEMA6D PHLDB2 VEPH1

4.44e-05195454a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DLG2 SEMA6D C17orf100 ATP8A2

4.62e-051974543a0e97bfebe82f9687d518baaad7f20d0ffea8a1
ToppCellASK440-Epithelial-Type_1|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

COL12A1 SEMA6D EXPH5 VEPH1

4.62e-051974541eda2c2504451a3d626dda5c2b2b12eeaa6bca54
ToppCellASK440-Epithelial-Type_1|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

COL12A1 C5orf24 SEMA6D PHLDB2

4.62e-05197454782449c522c9e16e72bf999a73090688a3aefe06
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K20 NAV2 COL12A1 PTGIR

4.62e-051974549b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NAV2 EXPH5 PHLDB2 VEPH1

4.71e-05198454b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCellControl_saline-Epithelial_alveolar-AT_1|Control_saline / Treatment groups by lineage, cell group, cell type

NAV2 EXPH5 PHLDB2 VEPH1

4.71e-051984549b161285df7a4e51618f3517cfc5b8221ba55786
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT1|Control_saline / Treatment groups by lineage, cell group, cell type

NAV2 EXPH5 PHLDB2 VEPH1

4.71e-0519845485f424cd9bb3117c9e322031024aabb87696ce47
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

RBM15 MSH4 PTGIR FREM1

4.71e-051984540c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCellASK428-Epithelial-Type_1|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

NAV2 COL12A1 SEMA6D PHLDB2

4.71e-051984540047a9ef7684230ac5179efea94461480e90bdaf
ToppCellmedial-2-Endothelial-Capillary_Aerocyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MIER2 SEMA6A CASKIN2 EXPH5

4.80e-05199454c5048b31649a0b7eddcd481b0458ed96508f5561
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NAV2 EXPH5 PHLDB2 VEPH1

4.80e-05199454a270630626df614f8605abddb7dee7c4d74f6149
ToppCellmedial-Endothelial-Capillary_Aerocyte|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MIER2 SEMA6A CASKIN2 EXPH5

4.80e-0519945484e30c39c2f050aa64af167999824c1cba32ba05
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NAV2 EXPH5 PHLDB2 VEPH1

4.80e-05199454d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NAV2 EXPH5 PHLDB2 VEPH1

4.80e-051994541c70e7d6bd25980e1b92aa1cac3f3c95d9651b4b
ToppCellmedial-Endothelial-Capillary_Aerocyte-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MIER2 SEMA6A CASKIN2 EXPH5

4.80e-05199454f1039d1ab498fc58f0feba545df05833c235db74
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-B3GAT2|Neuronal / cells hierarchy compared to all cells using T-Statistic

NAV2 SEMA6A VAV2 FREM1

4.89e-05200454858421b91f5207b7934b5c219752cb9322a3da31
ToppCelldistal-3-Endothelial-Capillary_Aerocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MIER2 SEMA6A CASKIN2 EXPH5

4.89e-05200454e12598a097dd9c4cbf9bb85bfa3057722ef73ad5
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MIER2 SEMA6A CASKIN2 EXPH5

4.89e-052004543653002c805c314043e2a7b0c9980dfe952dc53e
ToppCellmedial-2-Endothelial-Capillary_Intermediate_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MIER2 SEMA6A CASKIN2 EXPH5

4.89e-05200454a8adf5902540f6bb15b72efbb9c389b59d67e001
ToppCellTracheal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NAV2 DLG2 FREM1 PHLDB2

4.89e-05200454c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCelldistal-Endothelial-Capillary_Aerocyte|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MIER2 SEMA6A CASKIN2 EXPH5

4.89e-05200454b91f8eb67752a77e1e08e462e50f1b5923695e1b
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NAV2 EXPH5 PHLDB2 VEPH1

4.89e-05200454ddfb1f006365bf16203ee49f20200f68220cc288
ToppCellmedial-Endothelial-Capillary_Intermediate_1|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MIER2 SEMA6A CASKIN2 EXPH5

4.89e-052004543ef7b7728615710c691aed8977e2582f19692cf9
ToppCelldistal-1-Endothelial-Capillary_Aerocyte|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MIER2 SEMA6A CASKIN2 EXPH5

4.89e-0520045459bacd738433cec6d05624a25fdfc087fb3ca3b5
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NAV2 EXPH5 PHLDB2 VEPH1

4.89e-052004548683445ad5b70748c4a1f12eb77d47623085147e
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-B3GAT2-|Neuronal / cells hierarchy compared to all cells using T-Statistic

NAV2 SEMA6A VAV2 FREM1

4.89e-05200454a7022762c1d8aedb7b3e9605873b1e68b9907b35
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-B3GAT2--L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

NAV2 SEMA6A VAV2 FREM1

4.89e-052004542131c8e7fa054b79906eaf60536da892438b09cd
ToppCelldistal-Endothelial-Capillary_Aerocyte-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MIER2 SEMA6A CASKIN2 EXPH5

4.89e-05200454d36236c7703b759309c8347f44900fc4bed377f0
ToppCelldistal-2-Endothelial-Capillary_Intermediate_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MIER2 SEMA6A CASKIN2 EXPH5

4.89e-052004547a99f28670ffb8ece7873d8a9bcd2a3936d0255d
ToppCellmedial-Endothelial-Capillary_Intermediate_1-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MIER2 SEMA6A CASKIN2 EXPH5

4.89e-05200454707148e01e961097819a05437a842b7d3bf72b0a
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Vip_Nptx2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KCTD12 VAV2 FREM1

2.54e-041224531720756e0b3e8db14a9ccabe83f9b41689a4f754
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

VWA3A EXPH5 MYPN

2.54e-04122453a7df7c9865364574833b79781281f156b9268ab1
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-immature_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAV2 IFT88 CASKIN2

3.20e-041324539936078c328b1e1d59f9dfdd69d36926a0cdaf0d
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sncg|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KCTD12 VAV2 FREM1

3.27e-04133453840e8240db29cd21ed9830843c0fa6d65b8f300a
ToppCellAT1-AT2_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

NAV2 COL12A1 EXPH5

3.80e-0414045345d52a086ced8d58e01ac51ac4a90338e8649b16
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sncg|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KCTD12 VAV2 FREM1

3.96e-04142453ed91d2ef4c346f7e1a5402846e2a34cee19c24d1
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3|E16.5-samps / Age Group, Lineage, Cell class and subclass

ZNF318 COL12A1 FREM1

4.56e-04149453651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA3A KCTD12 GABRA1

4.93e-041534533b1b0cc8e9dd2b1484649789330713282ee44414
ToppCellAT1-AT2_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

DLG2 COL12A1 PHLDB2

5.12e-04155453010e45ef4b505bf419ea41e4d1619521d1c78319
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K20 NAV2 COL12A1

5.12e-0415545382e602f31981c6b48abff2a04b2ab5d26d4462a2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAP3K20 NAV2 COL12A1

5.12e-04155453979c1d53b435a82c57d16707eed8ba7346326866
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NAV1 KCTD12 FIGLA

5.31e-04157453e9d0300361b06aec3c216f8af15f09e14b12a4da
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NAV1 KCTD12 FIGLA

5.41e-04158453e9657d8960d499832f9f9b45b5a6f4388551b7e1
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTGIR VAV2 TRPS1

5.41e-0415845391d265e95156f16459924d3e4dd11c180e164eee
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA3A COL12A1 FREM1

5.61e-04160453c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA3A COL12A1 FREM1

5.61e-0416045325c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCelldroplet-Liver-HEPATOCYTES-1m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP39 SEMA6D CEP95

5.61e-04160453a494001b1f6dec33624f98fa3c24bad6988d0425
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NAV2 COL12A1 PTGIR

5.72e-04161453a7e09cf2ca6cd70d40d08440fe9c5ab9befa1b79
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NAV2 COL12A1 PTGIR

5.72e-0416145308920a716f6ec62538e361211455a30ad726d7be
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTGIR VAV2 TRPS1

5.82e-0416245393bd29c52846c3156b8b0d2e39c552373efdfe93
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DLG2 ATP8A2 VEPH1

6.03e-04164453b0ed8cb6000ce8bf94444307e4b7b3574fa3fab2
ToppCell356C-Myeloid-Mast_cell|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DLG2 SEMA6D FREM1

6.03e-04164453b3192c443f4848e6a8afdb89c155f9ec42a154b0
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DLG2 ATP8A2 VEPH1

6.03e-041644533aea6207a011ad55a1aeb2ed9fb54d31b23694b5
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Tpbg|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MAP3K20 MYPN TRPS1

6.03e-04164453f0499e6c1b17c4df72b18b294e3b53ef723da2ac
ToppCell356C-Myeloid-Mast_cell-|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DLG2 SEMA6D FREM1

6.03e-04164453f7288ec4daf494dae770ea6c58bead27660ccae1
ToppCellControl|World / group, cell type (main and fine annotations)

NAV2 EXPH5 VEPH1

6.47e-04168453a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellControl-Epithelial_alveolar-Mes-like-AT1_Progenitor|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCTD12 ZNF318 VDAC3

6.47e-0416845349180994311b3f4f9ec338b1d35d8edd7422e3c9
ToppCellControl-Epithelial_alveolar-Mes-like|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCTD12 ZNF318 VDAC3

6.47e-041684533c2ce9cfaca8ceab9b29f918ab46afc69eba3330
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-5|TCGA-Bladder / Sample_Type by Project: Shred V9

MAPK8IP1 GABRA1 MRGPRG

6.58e-041694539c4e83fe8225d16173a103bf5a57b17d623be923
Diseasenon-alcoholic fatty liver disease, type 2 diabetes mellitus

DLG2 ATP8A2 VAV2 PHLDB2

2.42e-05110454EFO_0003095, MONDO_0005148
Diseaseperipheral arterial disease, traffic air pollution measurement

MIER2 NAV2 C17orf100 TRPS1

2.19e-04194454EFO_0004265, EFO_0007908
Diseaseinfluenza A (H1N1)

DLG2 FIGLA TRPS1

3.21e-0487453EFO_1001488
Diseasebiological sex

SEMA6A ARHGAP39 SEMA6D ZNF280D

4.17e-04230454PATO_0000047
Diseaseresponse to TNF antagonist, joint damage measurement

NAV2 DLG2

6.67e-0425452EFO_0004653, EFO_0005413
DiseaseR-6-hydroxywarfarin measurement

RBM15 SEMA6D TRPS1

7.08e-04114453EFO_0803327
Diseasetriacylglycerol 54:3 measurement

ATP8A2 MYPN

1.03e-0331452EFO_0010421
Diseasehemorrhoid

MAP3K20 MYO15A PHLDB2

1.47e-03147453EFO_0009552
Diseaseattention function measurement

DLG2 MSH4 MYPN

1.50e-03148453EFO_0007636
Diseasecorpus callosum anterior volume measurement

NAV2 TRPS1

1.63e-0339452EFO_0010295

Protein segments in the cluster

PeptideGeneStartEntry
GYTQTLRPGVKLTLS

VDAC3

246

Q9Y277
PSSYSRGLKNGALSR

ZNF280D

66

Q6N043
YSTRSSSGGRAPIKA

ARHGEF33

726

A8MVX0
GAKQSSPRVGTTRYT

C17orf100

6

A8MU93
IRSSVGPVRSSLGYK

ATP8A2

21

Q9NTI2
KRPSRGQTSTYGFLK

RBM15

406

Q96T37
TLSSTGYSPGTRKRK

ARHGAP39

481

Q9C0H5
APQRLGKSSSVTRLY

MYO15A

1751

Q9UKN7
GSGDTYRPKRPTTLN

MAPK8IP1

151

Q9UQF2
KYRLTGTRLSNSPRS

FSIP2

971

Q5CZC0
TRRLTGSNYPGLSIS

ECH1

16

Q13011
TRGNGKTVRPSSVYR

FREM1

1926

Q5H8C1
NTPGSIRRYSLGQVS

VEPH1

421

Q14D04
YRSGTKTGPRSAISI

EXPH5

1866

Q8NEV8
LLLSTLTGRSYGQPS

GABRA1

16

P14867
STLGSYATLTRRPGR

CASKIN2

821

Q8WXE0
VNSSSKPLIYSGLGR

MRGPRG

241

Q86SM5
RKYKGISSRIPVSSG

FAM126A

221

Q9BYI3
VTRPIATGYGSKTSL

IFT88

61

Q13099
TTKSAGYRTSTGRPL

C5orf24

96

Q7Z6I8
GYRTSTGRPLGTTKA

C5orf24

101

Q7Z6I8
LRQGSGTTASRFKSP

COL12A1

1076

Q99715
YSRKTTTQSLRGGLP

CEP95

536

Q96GE4
ISLNSSPRGRYSGKS

MAP3K20

686

Q9NYL2
SGSGSLRTNQKRSLY

DLG2

526

Q15700
LKRLPSGGYSSTENL

FIGLA

46

Q6QHK4
TPSQSLDGSRRSGYI

KCTD12

196

Q96CX2
QTRLGRRKYVPSGTT

MIER2

356

Q8N344
LSGPSGTGKTYLTNR

NAV1

1556

Q8NEY1
SVKPGSSTRSLGTLY

RUSC1

566

Q9BVN2
PRGSSGLVNSRQKSY

NBR1

856

Q14596
RRIILSGPSGTGKTY

NAV2

2151

Q8IVL1
YTKTPGGSRRLRSNI

MSH4

341

O15457
GKRGIVISRSTYPTS

SI

1476

P14410
LLNTTSSLSGYPLGR

PHLDB2

111

Q86SQ0
RGSPSYTQASLGLLT

TRPS1

801

Q9UHF7
SGRRVYQVLGSSSKT

ZSWIM7

61

Q19AV6
RNLTYVRGSVGPATS

PTGIR

6

P43119
AYNSLTRSGLKRTPS

SEMA6A

991

Q9H2E6
SGSIKGSRYFQSPSR

SRSF7

181

Q16629
LGSVRSTKIYTPGRK

DHX38

1196

Q92620
AGVTQTPRYLIKTRG

TRBV5-1

21

A0A578
GRLVQTRKSGYFPSS

VAV2

631

P52735
YTSNGTLPRTGLKRT

SEMA6D

1031

Q8NFY4
STGSTYGFLQPLTRL

ZNF318

1666

Q5VUA4
KKYPQGRGLRRTSSS

VWA3A

836

A6NCI4
SVRPSGSRYGSLTSK

MYPN

1276

Q86TC9