Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

VLDLR LRP12 LRP1 LRP1B LDLR

3.09e-1016495GO:0005041
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

VLDLR LRP12 LRP1 LRP1B LDLR

1.43e-0921495GO:0030228
GeneOntologyMolecularFunctioncalcium ion binding

HSPG2 VLDLR SLC8A1 FBN1 ENPP2 LRP1 LTBP2 LTBP3 RET LTBP4 LRP1B LDLR CRB2

1.98e-087494913GO:0005509
GeneOntologyMolecularFunctioncargo receptor activity

VLDLR LRP12 ENPP2 LRP1 LRP1B LDLR

6.01e-0885496GO:0038024
GeneOntologyMolecularFunctionvery-low-density lipoprotein particle receptor activity

VLDLR LDLR

3.53e-054492GO:0030229
GeneOntologyMolecularFunctiontransmembrane transporter binding

AKAP6 SLC8A1 HAP1 SCN10A KCNB2

6.28e-05172495GO:0044325
GeneOntologyMolecularFunctionextracellular matrix structural constituent

HSPG2 FBN1 LTBP2 LTBP4 SSPOP

9.56e-05188495GO:0005201
GeneOntologyMolecularFunctionlipoprotein particle receptor binding

HSPG2 DKK1 LRP1

1.19e-0439493GO:0070325
GeneOntologyMolecularFunctionclathrin heavy chain binding

LRP1 LDLR

3.83e-0412492GO:0032050
GeneOntologyMolecularFunctionco-SMAD binding

USP9X USP9Y

3.83e-0412492GO:0070410
GeneOntologyMolecularFunctiongrowth factor binding

HAP1 LTBP2 LTBP3 LTBP4

5.78e-04156494GO:0019838
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

SCN2A SCN10A

7.84e-0417492GO:0099508
GeneOntologyMolecularFunctionapolipoprotein binding

VLDLR LRP1

1.09e-0320492GO:0034185
GeneOntologyMolecularFunctiontransforming growth factor beta binding

LTBP3 LTBP4

1.85e-0326492GO:0050431
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN2A SCN10A

1.85e-0326492GO:0005248
GeneOntologyMolecularFunctionscavenger receptor activity

ENPP2 LRP1

1.99e-0327492GO:0005044
GeneOntologyMolecularFunctionamyloid-beta binding

HSPG2 LRP1 LDLR

2.01e-03102493GO:0001540
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor binding

HSPG2 DKK1

3.15e-0334492GO:0050750
GeneOntologyMolecularFunctionlipoprotein particle binding

VLDLR LDLR

3.33e-0335492GO:0071813
GeneOntologyMolecularFunctionprotein-lipid complex binding

VLDLR LDLR

3.33e-0335492GO:0071814
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

FBN1 DKK1 USP9X LRP1 LTBP2 LTBP3 USP9Y LTBP4 CRB2

7.43e-07445489GO:0141091
GeneOntologyBiologicalProcessreceptor-mediated endocytosis

HSPG2 VLDLR DKK1 CD14 HAP1 LRP1 LRP1B LDLR

9.98e-07337488GO:0006898
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

FBN1 DKK1 USP9X LRP1 LTBP2 LTBP3 USP9Y LTBP4 CRB2

1.44e-06482489GO:0007178
GeneOntologyBiologicalProcessendocytosis

HSPG2 VLDLR LRP12 DKK1 CD14 HAP1 LRP1 LRP5 LRP1B LDLR VAV2

2.34e-068274811GO:0006897
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

FBN1 USP9X LRP1 LTBP2 LTBP3 USP9Y LTBP4

3.28e-06276487GO:0007179
GeneOntologyBiologicalProcessimport into cell

HSPG2 VLDLR LRP12 SLC8A1 DKK1 CD14 HAP1 LRP1 LRP5 LRP1B LDLR VAV2

4.56e-0610744812GO:0098657
GeneOntologyBiologicalProcesscellular response to transforming growth factor beta stimulus

FBN1 USP9X LRP1 LTBP2 LTBP3 USP9Y LTBP4

1.19e-05336487GO:0071560
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

FBN1 DKK1 HAP1 USP9X LRP1 LTBP2 LTBP3 RET USP9Y LTBP4 VAV2 CRB2

1.25e-0511864812GO:0007167
GeneOntologyBiologicalProcessresponse to transforming growth factor beta

FBN1 USP9X LRP1 LTBP2 LTBP3 USP9Y LTBP4

1.36e-05343487GO:0071559
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

FBN1 DKK1 HAP1 USP9X LRP1 LTBP2 LTBP3 USP9Y LTBP4 CRB2

2.11e-058504810GO:0071363
GeneOntologyBiologicalProcessresponse to growth factor

FBN1 DKK1 HAP1 USP9X LRP1 LTBP2 LTBP3 USP9Y LTBP4 CRB2

2.92e-058834810GO:0070848
GeneOntologyBiologicalProcessnegative regulation of protein metabolic process

HSPG2 SLC8A1 DKK1 HAP1 USP9X LRP1 LRP5 TRIM44 LDLR KLHL31 CRB2

3.12e-0510884811GO:0051248
GeneOntologyBiologicalProcesspositive regulation of lysosomal protein catabolic process

LRP1 LDLR

5.28e-055482GO:1905167
GeneOntologyBiologicalProcessregulation of cell junction assembly

VLDLR DKK1 NRXN2 USP9X ENPP2 LRP1

7.78e-05309486GO:1901888
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SLC8A1 SCN2A SCN10A

8.00e-0536483GO:0086010
GeneOntologyBiologicalProcessBMP signaling pathway

FBN1 DKK1 USP9X USP9Y CRB2

9.27e-05197485GO:0030509
GeneOntologyBiologicalProcessaction potential

AKAP6 SLC8A1 SCN2A SCN10A KCNB2

1.02e-04201485GO:0001508
GeneOntologyBiologicalProcesspositive regulation of protein catabolic process in the vacuole

LRP1 LDLR

1.11e-047482GO:1904352
GeneOntologyBiologicalProcessresponse to BMP

FBN1 DKK1 USP9X USP9Y CRB2

1.40e-04215485GO:0071772
GeneOntologyBiologicalProcesscellular response to BMP stimulus

FBN1 DKK1 USP9X USP9Y CRB2

1.40e-04215485GO:0071773
GeneOntologyBiologicalProcessamyloid-beta clearance by cellular catabolic process

LRP1 LDLR

1.47e-048482GO:0150094
GeneOntologyBiologicalProcessamyloid fibril formation

HSPG2 USP9X LDLR

1.57e-0445483GO:1990000
GeneOntologyBiologicalProcesspositive regulation of cell differentiation

AKAP6 DKK1 HAP1 ENPP2 LRP1 LRP5 LTBP3 RET IL4R CRB2

2.46e-0411414810GO:0045597
GeneOntologyBiologicalProcessregulation of phosphate metabolic process

AKAP6 VLDLR SLC8A1 FBN1 DKK1 ENPP2 LRP5 RET PPP6R2 LDLR KLHL31

3.37e-0414214811GO:0019220
GeneOntologyBiologicalProcessregulation of phosphorus metabolic process

AKAP6 VLDLR SLC8A1 FBN1 DKK1 ENPP2 LRP5 RET PPP6R2 LDLR KLHL31

3.41e-0414234811GO:0051174
GeneOntologyBiologicalProcessregulation of lysosomal protein catabolic process

LRP1 LDLR

3.45e-0412482GO:1905165
GeneOntologyBiologicalProcesscell morphogenesis

HSPG2 VLDLR DKK1 WEE1 USP9X ENPP2 LRP1 FGD5 RET CFAP44

3.54e-0411944810GO:0000902
GeneOntologyBiologicalProcesscentral nervous system development

HSPG2 VLDLR DKK1 HAP1 USP9X ENPP2 SCN2A LRP1 LRP5 LDLR

3.61e-0411974810GO:0007417
GeneOntologyBiologicalProcesscirculatory system development

AKAP6 HSPG2 SLC8A1 FBN1 DKK1 LRP1 LRP5 ADAM12 LDLR VAV2 CRB2

3.82e-0414424811GO:0072359
GeneOntologyBiologicalProcessneuron development

HSPG2 VLDLR LRP12 DKK1 HAP1 WEE1 USP9X RP1L1 LRP1 RET CRB2

4.32e-0414634811GO:0048666
GeneOntologyBiologicalProcessregulation of protein catabolic process in the vacuole

LRP1 LDLR

4.74e-0414482GO:1904350
GeneOntologyBiologicalProcessnegative regulation of amyloid fibril formation

HSPG2 LDLR

4.74e-0414482GO:1905907
GeneOntologyBiologicalProcessregulation of protein modification process

AKAP6 VLDLR SLC8A1 FBN1 DKK1 ENPP2 LRP5 RET PPP6R2 TRIM44 KLHL31

4.99e-0414884811GO:0031399
GeneOntologyBiologicalProcesscholesterol metabolic process

VLDLR LRP1 LRP5 LDLR

5.58e-04163484GO:0008203
GeneOntologyBiologicalProcesscardiac muscle contraction

AKAP6 SLC8A1 SCN2A SCN10A

6.11e-04167484GO:0060048
GeneOntologyBiologicalProcessphosphatidylcholine catabolic process

ENPP2 LDLR

6.23e-0416482GO:0034638
GeneOntologyBiologicalProcessneuron cell-cell adhesion

NRXN2 RET

6.23e-0416482GO:0007158
GeneOntologyBiologicalProcesscholesterol import

LRP1 LDLR

6.23e-0416482GO:0070508
GeneOntologyBiologicalProcessregulation of postsynaptic neurotransmitter receptor activity

DLGAP2 NRXN2

7.05e-0417482GO:0098962
GeneOntologyBiologicalProcesssecondary alcohol metabolic process

VLDLR LRP1 LRP5 LDLR

7.44e-04176484GO:1902652
GeneOntologyBiologicalProcesssterol metabolic process

VLDLR LRP1 LRP5 LDLR

7.60e-04177484GO:0016125
GeneOntologyBiologicalProcessregulation of amyloid fibril formation

HSPG2 LDLR

8.84e-0419482GO:1905906
GeneOntologyBiologicalProcesscell migration involved in gastrulation

LRP5 CRB2

9.81e-0420482GO:0042074
GeneOntologyBiologicalProcessregulation of protein phosphorylation

AKAP6 VLDLR SLC8A1 FBN1 DKK1 ENPP2 LRP5 RET KLHL31

1.06e-031133489GO:0001932
GeneOntologyBiologicalProcessrelaxation of cardiac muscle

AKAP6 SLC8A1

1.08e-0321482GO:0055119
GeneOntologyBiologicalProcesscardiac muscle cell action potential

SLC8A1 SCN2A SCN10A

1.09e-0387483GO:0086001
GeneOntologyBiologicalProcessregulation of cardiac muscle contraction

AKAP6 SLC8A1 SCN10A

1.17e-0389483GO:0055117
GeneOntologyBiologicalProcessexport from cell

SLC8A1 FBN1 NRXN2 HAP1 LRP1 LRP5 LTBP2 LTBP4 IL4R

1.20e-031153489GO:0140352
GeneOntologyBiologicalProcesstube development

HSPG2 SLC8A1 FBN1 LRP1 LRP5 LTBP3 RET ADAM12 LDLR VAV2

1.24e-0314024810GO:0035295
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

FBN1 DKK1 LRP1 LTBP4 CRB2

1.24e-03347485GO:0090092
GeneOntologyBiologicalProcessregulation of muscle contraction

AKAP6 SLC8A1 SCN10A KCNB2

1.24e-03202484GO:0006937
GeneOntologyBiologicalProcessregulation of synapse assembly

VLDLR DKK1 NRXN2 USP9X

1.24e-03202484GO:0051963
GeneOntologyBiologicalProcesscardiac muscle cell contraction

AKAP6 SCN2A SCN10A

1.33e-0393483GO:0086003
GeneOntologyCellularComponentplasma membrane protein complex

HSPG2 SCN2A SCN10A LRP1 LRP5 RET C9 KCNB2 SSPOP CRB2

1.66e-057855110GO:0098797
GeneOntologyCellularComponentclathrin-coated pit

VLDLR LRP12 LRP1 LDLR

4.33e-0580514GO:0005905
GeneOntologyCellularComponentreceptor complex

VLDLR CD14 LRP1 LRP5 RET LRP1B LDLR IL4R

7.54e-05581518GO:0043235
GeneOntologyCellularComponentmembrane protein complex

AKAP6 HSPG2 CD14 SCN2A SCN10A LRP1 LRP5 RET C9 KCNB2 SSPOP CRB2

2.02e-0414985112GO:0098796
GeneOntologyCellularComponentcollagen-containing extracellular matrix

HSPG2 FBN1 COL20A1 LTBP2 LTBP3 LTBP4 SSPOP

2.85e-04530517GO:0062023
GeneOntologyCellularComponentmicrofibril

FBN1 LTBP4

4.47e-0413512GO:0001527
GeneOntologyCellularComponentintercalated disc

AKAP6 SLC8A1 SCN2A

6.13e-0468513GO:0014704
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN2A SCN10A

7.75e-0417512GO:0001518
GeneOntologyCellularComponentT-tubule

AKAP6 SLC8A1 SCN2A

9.49e-0479513GO:0030315
GeneOntologyCellularComponentextracellular matrix

HSPG2 FBN1 COL20A1 LTBP2 LTBP3 LTBP4 SSPOP

1.01e-03656517GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

HSPG2 FBN1 COL20A1 LTBP2 LTBP3 LTBP4 SSPOP

1.03e-03658517GO:0030312
GeneOntologyCellularComponentearly endosome

DKK1 HAP1 LRP1 FGD5 RET LDLR

1.08e-03481516GO:0005769
GeneOntologyCellularComponentcell-cell contact zone

AKAP6 SLC8A1 SCN2A

1.57e-0394513GO:0044291
GeneOntologyCellularComponentsodium channel complex

SCN2A SCN10A

2.27e-0329512GO:0034706
GeneOntologyCellularComponentcation channel complex

AKAP6 SCN2A SCN10A KCNB2

2.57e-03235514GO:0034703
GeneOntologyCellularComponentsynaptic membrane

SLC8A1 NRXN2 SCN2A SCN10A RNF10 LRP1

2.85e-03583516GO:0097060
GeneOntologyCellularComponentglutamatergic synapse

DLGAP2 VLDLR NRXN2 SCN2A SCN10A RNF10 LRP1

3.51e-03817517GO:0098978
HumanPhenoFifth metacarpal with ulnar notch

FBN1 LTBP3

1.78e-052222HP:0005900
HumanPhenoHoarse voice

LRP12 FBN1 DKK1 LTBP3 RET LTBP4

4.15e-05159226HP:0001609
DomainLdl_recept_a

HSPG2 VLDLR LRP12 LRP1 LRP5 TMPRSS4 C9 LRP1B SSPOP LDLR

2.16e-17455010PF00057
Domain-

HSPG2 VLDLR LRP12 LRP1 LRP5 TMPRSS4 C9 LRP1B SSPOP LDLR

2.75e-174650104.10.400.10
DomainEGF_3

HSPG2 VLDLR FBN1 NRXN2 LRP1 LRP5 LTBP2 LTBP3 C9 ADAM12 LTBP4 LRP1B SSPOP LDLR CRB2

3.05e-172355015PS50026
DomainLDLRA_1

HSPG2 VLDLR LRP12 LRP1 LRP5 TMPRSS4 C9 LRP1B SSPOP LDLR

4.39e-17485010PS01209
DomainLDLRA_2

HSPG2 VLDLR LRP12 LRP1 LRP5 TMPRSS4 C9 LRP1B SSPOP LDLR

5.51e-17495010PS50068
DomainLDrepeatLR_classA_rpt

HSPG2 VLDLR LRP12 LRP1 LRP5 TMPRSS4 C9 LRP1B SSPOP LDLR

5.51e-17495010IPR002172
DomainLDLa

HSPG2 VLDLR LRP12 LRP1 LRP5 TMPRSS4 C9 LRP1B SSPOP LDLR

5.51e-17495010SM00192
DomainEGF_1

HSPG2 VLDLR FBN1 NRXN2 LRP1 LRP5 LTBP2 LTBP3 C9 ADAM12 LTBP4 LRP1B SSPOP LDLR CRB2

1.04e-162555015PS00022
DomainEGF_2

HSPG2 VLDLR FBN1 NRXN2 LRP1 LRP5 LTBP2 LTBP3 C9 ADAM12 LTBP4 LRP1B SSPOP LDLR CRB2

1.85e-162655015PS01186
DomainLDLR_class-A_CS

HSPG2 VLDLR LRP12 LRP1 LRP5 C9 LRP1B SSPOP LDLR

8.47e-1640509IPR023415
DomainEGF-like_dom

HSPG2 VLDLR FBN1 NRXN2 LRP1 LRP5 LTBP2 LTBP3 C9 ADAM12 LTBP4 LRP1B LDLR CRB2

2.38e-152495014IPR000742
DomainEGF-like_CS

HSPG2 VLDLR FBN1 NRXN2 LRP1 LRP5 LTBP2 LTBP3 C9 ADAM12 LTBP4 LRP1B LDLR CRB2

4.58e-152615014IPR013032
DomainEGF-like_Ca-bd_dom

HSPG2 VLDLR FBN1 LRP1 LRP5 LTBP2 LTBP3 LTBP4 LRP1B LDLR CRB2

2.11e-141245011IPR001881
DomainEGF_CA

VLDLR FBN1 LRP1 LRP5 LTBP2 LTBP3 LTBP4 LRP1B LDLR CRB2

9.47e-14995010PS01187
DomainGrowth_fac_rcpt_

HSPG2 VLDLR TNFRSF9 FBN1 LRP1 LTBP2 LTBP3 C9 LTBP4 LRP1B LDLR

2.73e-131565011IPR009030
DomainEGF_CA

HSPG2 VLDLR FBN1 LRP1 LTBP2 LTBP3 LTBP4 LRP1B LDLR CRB2

8.01e-131225010SM00179
DomainEGF

HSPG2 VLDLR FBN1 NRXN2 LRP1 LRP5 LTBP2 LTBP3 LTBP4 LRP1B LDLR CRB2

9.46e-132355012SM00181
DomainEGF_Ca-bd_CS

VLDLR FBN1 LRP1 LTBP2 LTBP3 LTBP4 LRP1B LDLR CRB2

3.95e-1297509IPR018097
DomainASX_HYDROXYL

VLDLR FBN1 LRP1 LTBP2 LTBP3 LTBP4 LRP1B LDLR CRB2

5.23e-12100509PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

VLDLR FBN1 LRP1 LTBP2 LTBP3 LTBP4 LRP1B LDLR CRB2

8.93e-12106509IPR000152
DomainEGF_CA

VLDLR FBN1 LRP1 LTBP2 LTBP3 LTBP4 LRP1B LDLR

6.64e-1186508PF07645
DomainLdl_recept_b

VLDLR LRP1 LRP5 LRP1B LDLR

2.20e-1014505PF00058
DomainLDLRB

VLDLR LRP1 LRP5 LRP1B LDLR

2.20e-1014505PS51120
DomainLY

VLDLR LRP1 LRP5 LRP1B LDLR

3.29e-1015505SM00135
DomainLDLR_classB_rpt

VLDLR LRP1 LRP5 LRP1B LDLR

3.29e-1015505IPR000033
DomainEGF

HSPG2 VLDLR NRXN2 LRP1 LRP5 LTBP2 LRP1B CRB2

1.45e-09126508PF00008
DomainTB

FBN1 LTBP2 LTBP3 LTBP4

1.58e-097504PF00683
Domain-

FBN1 LTBP2 LTBP3 LTBP4

3.16e-0985043.90.290.10
DomainTB

FBN1 LTBP2 LTBP3 LTBP4

5.67e-099504PS51364
DomainTB_dom

FBN1 LTBP2 LTBP3 LTBP4

5.67e-099504IPR017878
Domain-

VLDLR LRP1 LRP5 LRP1B LDLR

6.02e-08395052.120.10.30
Domain6-blade_b-propeller_TolB-like

VLDLR LRP1 LRP5 LRP1B LDLR

1.41e-0746505IPR011042
DomaincEGF

FBN1 LRP1 LTBP3 LRP1B

6.50e-0726504IPR026823
DomaincEGF

FBN1 LRP1 LTBP3 LRP1B

6.50e-0726504PF12662
DomainDUF5050

LRP1 LRP1B

7.02e-062502IPR032485
DomainDUF5050

LRP1 LRP1B

7.02e-062502PF16472
DomainLaminin_G

HSPG2 NRXN2 COL20A1 CRB2

1.73e-0558504IPR001791
DomainLAM_G_DOMAIN

HSPG2 NRXN2 CRB2

1.43e-0438503PS50025
DomainLaminin_G_2

HSPG2 NRXN2 CRB2

1.66e-0440503PF02210
DomainLamG

HSPG2 NRXN2 CRB2

2.21e-0444503SM00282
DomainNa_channel_asu

SCN2A SCN10A

3.12e-0410502IPR001696
DomainNa_trans_assoc

SCN2A SCN10A

3.12e-0410502IPR010526
DomainNa_trans_assoc

SCN2A SCN10A

3.12e-0410502PF06512
DomainEGF_extracell

LTBP2 ADAM12 LRP1B

5.55e-0460503IPR013111
DomainEGF_2

LTBP2 ADAM12 LRP1B

5.55e-0460503PF07974
Domain-

HSPG2 NRXN2 CRB2

2.10e-03955032.60.120.200
DomainhEGF

LTBP3 CRB2

2.54e-0328502PF12661
DomainConA-like_dom

HSPG2 NRXN2 COL20A1 CRB2

2.78e-03219504IPR013320
DomainIon_trans_dom

SCN2A SCN10A KCNB2

3.52e-03114503IPR005821
DomainIon_trans

SCN2A SCN10A KCNB2

3.52e-03114503PF00520
Domainzf-RING_2

PHRF1 RNF10

8.55e-0352502PF13639
PathwayKEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA

FBN1 LTBP3 LTBP4

1.27e-068413M47850
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN1 LTBP2 LTBP3 LTBP4

2.09e-0632414MM14854
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

FBN1 USP9X LTBP2 LTBP3 LTBP4

2.74e-0677415MM14670
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN1 LTBP2 LTBP3 LTBP4

3.79e-0637414M27134
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

FBN1 LTBP2 LTBP3 LTBP4

4.23e-0638414MM14874
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN1 LTBP2 LTBP3 LTBP4

4.71e-0639414MM14601
PathwayWP_FAMILIAL_HYPERLIPIDEMIA_TYPE_3

VLDLR LRP1 LDLR

6.40e-0613413M42551
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

FBN1 USP9X LTBP2 LTBP3 LTBP4

7.34e-0694415M1041
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN1 LTBP2 LTBP3 LTBP4

7.68e-0644414M26969
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

FBN1 LTBP2 LTBP3 LTBP4

1.00e-0547414M646
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

HSPG2 LRP12 LRP1 LDLR

1.09e-0548414M27642
PathwayWP_FATTY_ACIDS_AND_LIPOPROTEINS_TRANSPORT_IN_HEPATOCYTES

VLDLR LRP12 ENPP2 LRP1 LRP5 TMPRSS4 LRP1B LDLR

1.16e-05381418M48063
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

FBN1 USP9X LTBP2 LTBP3 LTBP4

2.22e-05118415MM15588
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

HSPG2 FBN1 COL20A1 LTBP2 LTBP3 ADAM12 LTBP4

2.23e-05300417M610
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

FBN1 COL20A1 LTBP2 LTBP3 ADAM12 LTBP4

9.31e-05258416MM14572
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

FBN1 USP9X LTBP2 LTBP3 LTBP4

9.82e-05161415M27871
PathwayREACTOME_SIGNALING_BY_LRP5_MUTANTS

DKK1 LRP5

1.23e-046412M27432
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

HSPG2 LRP12 LRP1 LDLR

1.97e-04100414M27158
PathwayREACTOME_NEGATIVE_REGULATION_OF_TCF_DEPENDENT_SIGNALING_BY_WNT_LIGAND_ANTAGONISTS

DKK1 LRP5

2.29e-048412MM14976
PathwayREACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS

HSPG2 LRP12 ENPP2 LRP1 LDLR

2.58e-04198415M18311
PathwayREACTOME_NEGATIVE_REGULATION_OF_TCF_DEPENDENT_SIGNALING_BY_WNT_LIGAND_ANTAGONISTS

DKK1 LRP5

8.46e-0415412M27273
PathwayWP_FAMILIAL_HYPERLIPIDEMIA_TYPE_5

LRP1 LDLR

8.46e-0415412M42552
PathwayWP_FAMILIAL_HYPERLIPIDEMIA_TYPE_1

LRP1 LDLR

1.23e-0318412M42559
PathwayWP_STATIN_PATHWAY

LRP1 LDLR

1.37e-0319412MM15868
PathwayWP_FAMILIAL_HYPERLIPIDEMIA_TYPE_4

LRP1 LDLR

1.84e-0322412M42574
PathwayREACTOME_RESPIRATORY_SYNCYTIAL_VIRUS_RSV_ATTACHMENT_AND_ENTRY

HSPG2 CD14

2.01e-0323412M48234
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

VLDLR LRP1 LRP5 LRP1B LDLR

1.11e-102151521337463
Pubmed

The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL activity and involves proteoglycans and SR-BI.

VLDLR LRP1 LDLR

2.97e-09351318367731
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

VLDLR LRP1 RET LRP1B LDLR IL4R

8.36e-0910151623382219
Pubmed

Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability.

LTBP2 LTBP3 LTBP4

1.19e-08451315611103
Pubmed

The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor.

VLDLR LRP1 LDLR

1.19e-08451315863833
Pubmed

The latent transforming growth factor beta binding protein (LTBP) family.

LTBP2 LTBP3 LTBP4

1.19e-08451311104663
Pubmed

LDL receptor cooperates with LDL receptor-related protein in regulating plasma levels of coagulation factor VIII in vivo.

VLDLR LRP1 LDLR

1.19e-08451315840700
Pubmed

Interaction of coagulation factor VIII with members of the low-density lipoprotein receptor family follows common mechanism and involves consensus residues within the A2 binding site 484-509.

VLDLR LRP1 LDLR

2.96e-08551318685438
Pubmed

Cloning of a complementary deoxyribonucleic acid encoding the murine homolog of the very low density lipoprotein/apolipoprotein-E receptor: expression pattern and assignment of the gene to mouse chromosome 19.

VLDLR LRP1 LDLR

2.96e-0855138013374
Pubmed

Critical Role of SREBP-1c Large-VLDL Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency.

VLDLR LRP1 LDLR

2.96e-08551330700132
Pubmed

Normal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemia.

VLDLR LRP1 LDLR

2.96e-08551312746448
Pubmed

Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo.

VLDLR LRP1 LDLR

2.96e-08551318992221
Pubmed

Low levels of copper disrupt brain amyloid-β homeostasis by altering its production and clearance.

VLDLR LRP1 LDLR

2.96e-08551323959870
Pubmed

Apolipoprotein CI causes hypertriglyceridemia independent of the very-low-density lipoprotein receptor and apolipoprotein CIII in mice.

VLDLR LRP1 LDLR

5.92e-08651316478678
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

LRP12 FBN1 LRP1 LTBP3 SSPOP

6.71e-087151533541421
Pubmed

Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta.

LTBP2 LTBP3 LTBP4

1.04e-07751310930463
Pubmed

The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.

VLDLR LRP1 LDLR

1.04e-07751312169628
Pubmed

Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2.

VLDLR LRP1 LDLR

1.65e-07851310380922
Pubmed

Targeted inactivation of the mouse alpha 2-macroglobulin gene.

VLDLR LRP1 LDLR

2.48e-0795137544347
Pubmed

Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.

VLDLR LRP1 LDLR

2.48e-07951320005821
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP1 LRP5 LRP1B

4.86e-071151324639464
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

HSPG2 FBN1 LRP1 LTBP3 LTBP4

8.56e-0711851521078624
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

HSPG2 LRP12 FBN1 LRP1 LRP5 LTBP2 LTBP3 PPP6R2 ADAM12 LRP1B LDLR

1.07e-061201511135696571
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

VLDLR LRP1 LRP1B

1.07e-061451315082773
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

VLDLR LRP1 LDLR

1.07e-061451317389516
Pubmed

Selective disruption of trigeminal sensory neurogenesis and differentiation in a mouse model of 22q11.2 deletion syndrome.

FBN1 SCN10A RET

1.33e-061551333722956
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

HSPG2 FBN1 LTBP2 ADAM12 LTBP4 LDLR

1.70e-0624851624006456
Pubmed

RET signaling is required for survival and normal function of nonpeptidergic nociceptors.

SCN10A RET

2.11e-06251220237269
Pubmed

Striking differences of LDL receptor-related protein 1B expression in mouse and human.

LRP1 LRP1B

2.11e-06251215963947
Pubmed

Genetic analysis of the contribution of LTBP-3 to thoracic aneurysm in Marfan syndrome.

FBN1 LTBP3

2.11e-06251226494287
Pubmed

A neuronal VLDLR variant lacking the third complement-type repeat exhibits high capacity binding of apoE containing lipoproteins.

VLDLR LDLR

2.11e-06251219393635
Pubmed

Low density lipoprotein receptor-related protein polymorphisms are not risk factors for venous thromboembolism.

LRP1 LDLR

2.11e-06251217889283
Pubmed

Control of lung development by latent TGF-β binding proteins.

LTBP3 LTBP4

2.11e-06251220945348
Pubmed

The A1330V polymorphism of the low-density lipoprotein receptor-related protein 5 gene (LRP5) associates with low peak bone mass in young healthy men.

LRP5 LDLR

2.11e-06251217223614
Pubmed

Upregulation of hepatic LDL transport by n-3 fatty acids in LDL receptor knockout mice.

LRP1 LDLR

2.11e-06251211971949
Pubmed

A practical overview of pediatric atopic dermatitis, part 2: triggers and grading.

CD14 IL4R

2.11e-06251227274543
Pubmed

LRP: role in vascular wall integrity and protection from atherosclerosis.

LRP1 LDLR

2.11e-06251212690199
Pubmed

Ubiquitin-specific protease activity of USP9Y, a male infertility gene on the Y chromosome.

USP9X USP9Y

2.11e-06251212895410
Pubmed

Genetic analysis of high bone mass cases from the BARCOS cohort of Spanish postmenopausal women.

DKK1 LRP5

2.11e-06251224736728
Pubmed

Identification and characterization of LTBP-2, a novel latent transforming growth factor-beta-binding protein.

LTBP2 LTBP3

2.11e-0625127798248
Pubmed

Exome sequencing identified new mutations in a Marfan syndrome family.

FBN1 LRP1

2.11e-06251224484584
Pubmed

Genetic modifiers affecting severity of epilepsy caused by mutation of sodium channel Scn2a.

DKK1 SCN2A

2.11e-06251216245025
Pubmed

Absence of LTBP-3 attenuates the aneurysmal phenotype but not spinal effects on the aorta in Marfan syndrome.

FBN1 LTBP3

2.11e-06251230306291
Pubmed

Confocal microscopy demonstrates association of LTBP-2 in fibrillin-1 microfibrils and colocalisation with perlecan in the disc cell pericellular matrix.

FBN1 LTBP2

2.11e-06251224867584
Pubmed

The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2.

USP9X USP9Y

2.11e-0625128922996
Pubmed

Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants.

LRP1 LDLR

2.11e-0625129449704
Pubmed

Reduced affinity to and inhibition by DKK1 form a common mechanism by which high bone mass-associated missense mutations in LRP5 affect canonical Wnt signaling.

DKK1 LRP5

2.11e-06251215923613
Pubmed

Microfibrils at basement membrane zones interact with perlecan via fibrillin-1.

HSPG2 FBN1

2.11e-06251215657057
Pubmed

Latent TGF-β binding protein 2 and 4 have essential overlapping functions in microfibril development.

LTBP2 LTBP4

2.11e-06251228252045
Pubmed

LRP1 functions as an atheroprotective integrator of TGFbeta and PDFG signals in the vascular wall: implications for Marfan syndrome.

LRP1 LDLR

2.11e-06251217505534
Pubmed

8-Cysteine TGF-BP structural motifs are the site of covalent binding between mouse LTBP-3, LTBP-2, and latent TGF-beta 1.

LTBP2 LTBP3

2.11e-0625129602168
Pubmed

Modulation of Wnt signaling influences fracture repair.

DKK1 LRP5

2.11e-06251220063381
Pubmed

LTBP3 Pathogenic Variants Predispose Individuals to Thoracic Aortic Aneurysms and Dissections.

FBN1 LTBP3

2.11e-06251229625025
Pubmed

Reversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor.

VLDLR LDLR

2.11e-06251210024503
Pubmed

Comparative immunolocalisation of fibrillin-1 and perlecan in the human foetal, and HS-deficient hspg2 exon 3 null mutant mouse intervertebral disc.

HSPG2 FBN1

2.11e-06251223104139
Pubmed

Usp9y (ubiquitin-specific protease 9 gene on the Y) is associated with a functional promoter and encodes an intact open reading frame homologous to Usp9x that is under selective constraint.

USP9X USP9Y

2.11e-06251212925892
Pubmed

Wnt signalling: antagonistic Dickkopfs.

DKK1 LRP5

2.11e-06251211516963
Pubmed

LDL receptor deficiency unmasks altered VLDL triglyceride metabolism in VLDL receptor transgenic and knockout mice.

VLDLR LDLR

2.11e-06251211108739
Pubmed

Clearance of coagulation factor VIII in very low-density lipoprotein receptor knockout mice.

VLDLR LRP1

2.11e-06251215327526
Pubmed

Pharmacological Inhibition of Wee1 Kinase Selectively Modulates the Voltage-Gated Na+ Channel 1.2 Macromolecular Complex.

WEE1 SCN2A

2.11e-06251234831326
Pubmed

The Fbn1 gene variant governs passive ascending aortic mechanics in the mgΔlpn mouse model of Marfan syndrome when superimposed to perlecan haploinsufficiency.

HSPG2 FBN1

2.11e-06251238545339
Pubmed

Low-density lipoprotein receptor-related protein 5 (LRP5) mediates the prostate cancer-induced formation of new bone.

DKK1 LRP5

2.11e-06251217700537
Pubmed

An extrahepatic receptor-associated protein-sensitive mechanism is involved in the metabolism of triglyceride-rich lipoproteins.

LRP1 LDLR

2.11e-06251210575007
Pubmed

Common genetic variation in the DKK1 gene is associated with hip axis length but not with bone mineral density and bone turnover markers in young adult men: results from the Odense Androgen Study.

DKK1 LRP5

2.11e-06251220101398
Pubmed

CD14 and IL4R gene polymorphisms modify the effect of day care attendance on serum IgE levels.

CD14 IL4R

2.11e-06251219447482
Pubmed

Is HSPG2 a modifier gene for Marfan syndrome?

HSPG2 FBN1

2.11e-06251232514132
Pubmed

LDL-receptor mRNA expression in men is downregulated within an hour of an acute fat load and is influenced by genetic polymorphism.

LRP1 LDLR

2.11e-06251217709443
Pubmed

Deletion of LRP5 in VLDLR knockout mice inhibits retinal neovascularization.

VLDLR LRP5

2.11e-06251224058663
Pubmed

Reversal of hypercholesterolemia in low density lipoprotein receptor knockout mice by adenovirus-mediated gene transfer of the very low density lipoprotein receptor.

VLDLR LDLR

2.11e-0625128636110
Pubmed

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.

VLDLR LRP1 LDLR

2.39e-061851310827173
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

HSPG2 FBN1 LTBP2 LTBP3 LTBP4

2.45e-0614651527068509
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

HSPG2 FBN1 LTBP2 LTBP4 SSPOP

5.93e-0617551528071719
Pubmed

Hepatic remnant lipoprotein clearance by heparan sulfate proteoglycans and low-density lipoprotein receptors depend on dietary conditions in mice.

LRP1 LDLR

6.32e-06351223846497
Pubmed

Inactivation of the LRP1 intracellular NPxYxxL motif in LDLR-deficient mice enhances postprandial dyslipidemia and atherosclerosis.

LRP1 LDLR

6.32e-06351219667105
Pubmed

Low-density lipoprotein receptor-related protein 1 prevents early atherosclerosis by limiting lesional apoptosis and inflammatory Ly-6Chigh monocytosis: evidence that the effects are not apolipoprotein E dependent.

LRP1 LDLR

6.32e-06351221730304
Pubmed

PCSK9 deficiency unmasks a sex- and tissue-specific subcellular distribution of the LDL and VLDL receptors in mice.

VLDLR LDLR

6.32e-06351226323289
Pubmed

High Bone Mass-Causing Mutant LRP5 Receptors Are Resistant to Endogenous Inhibitors In Vivo.

DKK1 LRP5

6.32e-06351225808845
Pubmed

Hexamethylene diisocyanate asthma is associated with genetic polymorphisms of CD14, IL-13, and IL-4 receptor α.

CD14 IL4R

6.32e-06351221489615
Pubmed

Association of the -159 CD14 gene polymorphism and lack of association of the -308 TNFA and Q551R IL-4RA polymorphisms with severe chronic periodontitis in Swedish Caucasians.

CD14 IL4R

6.32e-06351215842262
Pubmed

The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins.

LRP1 LDLR

6.32e-06351230100244
Pubmed

RAGE, LDL receptor, and LRP1 expression in the brains of SAMP8.

LRP1 LDLR

6.32e-06351219539695
Pubmed

The relationship among apolipoprotein(a) polymorphisms, the low-density lipoprotein receptor-related protein, and the very low density lipoprotein receptor genes, and plasma lipoprotein(A) concentration in the Czech population.

VLDLR LRP1

6.32e-06351211931574
Pubmed

Diisocyanate asthma and gene-environment interactions with IL4RA, CD-14, and IL-13 genes.

CD14 IL4R

6.32e-06351217201240
Pubmed

Proprotein convertase subtilisin/kexin type 9 (PCSK9) can mediate degradation of the low density lipoprotein receptor-related protein 1 (LRP-1).

LRP1 LDLR

6.32e-06351223675525
Pubmed

Identification of a Vav2-dependent mechanism for GDNF/Ret control of mesolimbic DAT trafficking.

RET VAV2

6.32e-06351226147533
Pubmed

Geleophysic Dysplasia

FBN1 LTBP3

6.32e-06351220301776
Pubmed

Hepatic low-density lipoprotein receptor-related protein deficiency in mice increases atherosclerosis independent of plasma cholesterol.

LRP1 LDLR

6.32e-06351214739216
Pubmed

Mouse very low-density lipoprotein receptor (VLDLR): gene structure, tissue-specific expression and dietary and developmental regulation.

VLDLR LDLR

6.32e-06351210488949
Pubmed

LDL Receptor-Related Protein-1 (LRP1) Regulates Cholesterol Accumulation in Macrophages.

LRP1 LDLR

6.32e-06351226061292
Pubmed

4-1BB engagement costimulates NKT cell activation and exacerbates NKT cell ligand-induced airway hyperresponsiveness and inflammation.

TNFRSF9 IL4R

6.32e-06351218250411
Pubmed

Atherosclerosis in perlecan heterozygous mice.

HSPG2 LDLR

6.32e-06351215258195
Pubmed

LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation.

LRP1 LDLR

6.32e-0635121423604
Pubmed

LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation.

LRP1 LDLR

6.32e-06351219742316
Pubmed

mTOR inhibition rescues osteopenia in mice with systemic sclerosis.

FBN1 IL4R

6.32e-06351225534817
Pubmed

Hematopoietic stem/progenitor cells directly contribute to arteriosclerotic progression via integrin β2.

LRP1 LDLR

6.32e-06351225546260
Pubmed

Autotaxin Derived From Lipoprotein(a) and Valve Interstitial Cells Promotes Inflammation and Mineralization of the Aortic Valve.

ENPP2 LDLR

6.32e-06351226224810
Pubmed

The binding sites for the very low density lipoprotein receptor and low-density lipoprotein receptor-related protein are shared within coagulation factor VIII.

VLDLR LRP1

6.32e-06351218277139
Pubmed

Deletion of the Mir-106b~ 25 MicroRNA cluster attenuates atherosclerosis in Apolipoprotein E knockout mice.

VLDLR LDLR

6.32e-06351231796057
Pubmed

A cell-based Dkk1 binding assay reveals roles for extracellular domains of LRP5 in Dkk1 interaction and highlights differences between wild-type and the high bone mass mutant LRP5(G171V).

DKK1 LRP5

6.32e-06351219746449
Pubmed

The low density lipoprotein receptor prevents secretion of dense apoB100-containing lipoproteins from the liver.

VLDLR LDLR

6.32e-06351214583618
InteractionZNF408 interactions

HSPG2 VLDLR FBN1 USP9X LTBP2 LTBP4 LRP1B LDLR

2.08e-09145498int:ZNF408
InteractionZFP41 interactions

FBN1 LRP1 LTBP4 LRP1B LDLR

2.62e-0757495int:ZFP41
InteractionNTN5 interactions

FBN1 LTBP4 LRP1B LDLR

3.16e-0724494int:NTN5
InteractionIGFL3 interactions

VLDLR LRP12 LRP5 LRP1B LDLR

1.05e-0675495int:IGFL3
InteractionFOXD4L6 interactions

PPP6R2 LTBP4 LRP1B LDLR

6.03e-0649494int:FOXD4L6
InteractionCACNA1A interactions

HSPG2 SCN10A LRP1 LTBP3 LTBP4

1.20e-05123495int:CACNA1A
InteractionZDHHC15 interactions

LRP12 FBN1 LRP1 LTBP3 SSPOP

1.30e-05125495int:ZDHHC15
InteractionCLU interactions

VLDLR LRP1 DHX57 RET C9 LRP1B

2.74e-05245496int:CLU
InteractionPRG2 interactions

HSPG2 LRP5 LTBP3 PPP6R2 LTBP4 LDLR

6.37e-05285496int:PRG2
InteractionWNT10A interactions

LRP5 LTBP3 LDLR

9.90e-0537493int:WNT10A
Cytoband10q11.2

DKK1 RET

1.09e-041451210q11.2
CytobandEnsembl 112 genes in cytogenetic band chr11q13

NRXN2 ZNF705EP LRP5 LTBP3

1.63e-03454514chr11q13
CytobandEnsembl 112 genes in cytogenetic band chr8p23

DLGAP2 RP1L1 ZNF705G

2.27e-03234513chr8p23
Cytoband11q13.4

ZNF705EP LRP5

3.19e-037551211q13.4
CytobandEnsembl 112 genes in cytogenetic band chr2p22

SLC8A1 DHX57

6.03e-03104512chr2p22
GeneFamilyLow density lipoprotein receptors

VLDLR LRP12 LRP1 LRP5 LRP1B LDLR

1.34e-1313406634
GeneFamilyLatent transforming growth factor beta binding proteins

LTBP2 LTBP3 LTBP4

4.01e-084403628
GeneFamilySodium voltage-gated channel alpha subunits

SCN2A SCN10A

1.70e-0494021203
GeneFamilyRing finger proteins

PHRF1 RNF10 TRIM44 PDZRN4

3.11e-0327540458
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

USP9Y PKN3

5.68e-0351402870
GeneFamilyUbiquitin specific peptidases

USP9X USP9Y

6.82e-0356402366
CoexpressionBMI1_DN.V1_UP

VLDLR TNFRSF9 DKK1 LRP5 ADAM12 LTBP4

3.64e-07147506M2782
CoexpressionNABA_CORE_MATRISOME

HSPG2 FBN1 COL20A1 LTBP2 LTBP3 LTBP4 SSPOP

7.79e-07270507MM17057
CoexpressionNABA_CORE_MATRISOME

HSPG2 FBN1 COL20A1 LTBP2 LTBP3 LTBP4 SSPOP

8.81e-07275507M5884
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

HSPG2 LRP12 PHRF1 RNF10 LRP1 LTBP2 LTBP3 LDLR IL4R

4.95e-06681509M5314
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

HSPG2 LRP12 PHRF1 RNF10 LRP1 LTBP2 LTBP3 LDLR IL4R

6.39e-06703509MM1055
CoexpressionNABA_ECM_GLYCOPROTEINS

FBN1 LTBP2 LTBP3 LTBP4 SSPOP

3.17e-05191505MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

FBN1 LTBP2 LTBP3 LTBP4 SSPOP

3.58e-05196505M3008
CoexpressionPETRETTO_CARDIAC_HYPERTROPHY

FBN1 ENPP2 LTBP3

3.75e-0534503M14043
CoexpressionGSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_MACROPHAGE_UP

AKAP6 LRP12 CD14 LRP1 C9

3.85e-05199505M8105
CoexpressionDESCARTES_FETAL_LUNG_MESOTHELIAL_CELLS

DKK1 KLHL31 CRB2 PDZRN4

4.86e-05105504M40242
CoexpressionRICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_UP

VLDLR FBN1 TMPRSS4 ADAM12

9.58e-05125504M15672
CoexpressionSASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION

VLDLR FBN1 LTBP2

1.20e-0450503M1259
CoexpressionSASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION

VLDLR FBN1 LTBP2

1.35e-0452503MM1118
CoexpressionDESCARTES_FETAL_THYMUS_STROMAL_CELLS

FBN1 LRP1 ADAM12 LTBP4

1.37e-04137504M40313
CoexpressionMEL18_DN.V1_UP

VLDLR TNFRSF9 ADAM12 LTBP4

1.52e-04141504M2784
CoexpressionBMI1_DN_MEL18_DN.V1_UP

VLDLR TNFRSF9 WEE1 ADAM12

1.70e-04145504M2779
CoexpressionOISHI_CHOLANGIOMA_STEM_CELL_LIKE_DN

HSPG2 FBN1 DKK1 LRP1 LTBP4

1.74e-04274505M289
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

AKAP6 LRP12 SLC8A1 NRXN2 SCN2A LRP1B SSPOP VAV2 PDZRN4

2.16e-041106509M39071
CoexpressionAtlasStromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4

HSPG2 FBN1 ENPP2 LRP1 LTBP2 ADAM12 LTBP4

5.15e-05455467GSM777055_500
CoexpressionAtlasStromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3

HSPG2 FBN1 ENPP2 LTBP4

5.76e-0597464GSM777043_100
CoexpressionAtlasStromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5

HSPG2 FBN1 ENPP2 LRP1 LTBP3 ADAM12 LTBP4

5.98e-05466467GSM777050_500
CoexpressionAtlaskidney_adult_RenalCapsule_k-means-cluster#2_top-relative-expression-ranked_1000

FBN1 SCN2A LRP1 LTBP2 LTBP3 LTBP4

1.38e-04369466gudmap_kidney_adult_RenalCapsule_k2_1000
CoexpressionAtlasMyeloid Cells, MF.RP.Sp, F4/80hi CD11blo CD11c- autofluorescent, Spleen, avg-3

SLC8A1 CD14 HAP1 ENPP2 LRP1 VAV2

2.22e-04403466GSM605853_500
CoexpressionAtlasJC_fibro_top-relative-expression-ranked_1000

AKAP6 SLC8A1 FBN1 FMO4 DKK1 ENPP2 LRP1 LTBP2 ADAM12

2.33e-04990469JC_fibro_1000
CoexpressionAtlaskidney_adult_RenalCapsule_top-relative-expression-ranked_500

VLDLR FBN1 CD14 SCN2A LRP1 LTBP4

2.37e-04408466gudmap_kidney_adult_RenalCapsule_500
CoexpressionAtlaskidney_adult_RenalCapsule_top-relative-expression-ranked_1000

VLDLR FBN1 CD14 SCN2A LRP1 LTBP2 LTBP3 LTBP4

2.38e-04778468gudmap_kidney_adult_RenalCapsule_1000
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FBN1 NRXN2 LRP1 LTBP2 LTBP3 KCNB2 LTBP4

2.93e-091995176b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCellLPS_only-Endothelial-Endothelial-Artery|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 SLC8A1 FBN1 FGD5 LTBP4 PKN3

7.81e-08189516b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCellLPS-IL1RA-Endothelial-Endothelial-Artery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 SLC8A1 FBN1 FGD5 LTBP4 PKN3

8.06e-08190516aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR FBN1 ENPP2 LRP1 LTBP3 PDZRN4

8.31e-081915169214655dca96d766737c9f30b624d7fe7050342e
ToppCellLPS-antiTNF-Endothelial-Endothelial-Artery|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 SLC8A1 FBN1 FGD5 LTBP4 PKN3

8.31e-081915164b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP9X ENPP2 TMPRSS4 RET ADAM12 LDLR

8.57e-081925165b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TNFRSF9 FBN1 DKK1 CD14 LTBP2 ADAM12

9.40e-081955161be9502577267ca2a04656a99d57e3e2f124d92e
ToppCellfacs-Trachea-nan-3m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 VLDLR FBN1 LRP1 LTBP3 LTBP4

1.03e-071985160dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

FBN1 LRP1 LTBP2 LTBP3 KCNB2 LTBP4

1.09e-07200516a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Fam159b|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ENPP2 FGD5 RET VAV2 PDZRN4

7.74e-0714951598ae408d2d0347865875ff8bbd89d359decea526
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HAP1 WEE1 SCN2A TMPRSS4 LRP1B

1.17e-06162515373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBN1 ENPP2 LRP1 LTBP4

1.66e-0617451568a6ed81e7e1f95b61f7ee20403980fa3a8db4d0
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DLGAP2 FBN1 LRP1 ADAM12 LTBP4

2.02e-06181515c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DLGAP2 FBN1 LRP1 ADAM12 LTBP4

2.02e-06181515c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKAP6 DLGAP2 DKK1 NRXN2 RET

2.07e-06182515be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

AKAP6 SLC8A1 CD14 ENPP2 C9

2.24e-061855158207f9eff113eed429e961748c6b17d672a13b33
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SLC8A1 SCN2A SCN10A LRP1 LRP1B

2.30e-0618651523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 FGD5 KCNB2 LTBP4 PKN3

2.36e-06187515e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 ENPP2 LRP1 LTBP4 LDLR

2.43e-061885152cfa41c64eccb28b5e22f0f91bbc921b75713245
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBN1 ENPP2 LRP1 LTBP4

2.43e-061885157191087d8754f5e8700e3d744cd920ee26db1e57
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 SLC8A1 FBN1 FGD5 PKN3

2.49e-06189515c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 ENPP2 LRP1 LTBP4 LDLR

2.49e-061895150a8b827bba1efd885ad6c06929251c741dc3a541
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 FBN1 FGD5 LTBP4 PKN3

2.49e-0618951512b6f1c3bf526b90e112374bf937701f645c5780
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)|Children_(3_yrs) / Lineage, Cell type, age group and donor

AKAP6 SLC8A1 CD14 ENPP2 C9

2.56e-06190515f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCellwk_08-11-Epithelial-PNS-Schwann_precursor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

NRXN2 COL20A1 RET ADAM12 PDZRN4

2.56e-061905154a777d8aa19cadd3b61b023772df142421a89113
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

VLDLR FBN1 LRP1 ADAM12 LTBP4

2.62e-061915153379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 VLDLR SLC8A1 KLHL31 PDZRN4

2.62e-06191515c172c9e17b893b290e4aa8af5e5e4cd3e4818372
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP9X ENPP2 TMPRSS4 ADAM12 LDLR

2.62e-06191515f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 VLDLR SLC8A1 KLHL31 PDZRN4

2.62e-06191515715f5b449b8e075959c05a5b38389df319663164
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBN1 ENPP2 LRP1 RET

2.69e-06192515671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCellfacs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBN1 LRP1 LTBP3 LTBP4

2.69e-06192515a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 LRP1 ADAM12 LTBP4 PDZRN4

2.69e-06192515d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCellfacs-Lung-nan-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBN1 LRP1 LTBP3 LTBP4

2.69e-06192515eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCellControl-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

HSPG2 SLC8A1 ENPP2 LTBP4 LRP1B

2.69e-061925157e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 FBN1 LRP1 LTBP3 LTBP4

2.69e-0619251532acd89617934016cd135d2cc797e8e79ae1b37f
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBN1 ENPP2 LRP1 RET

2.69e-06192515840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 VLDLR FBN1 ENPP2 LRP1

2.69e-061925152d9e2262f1342fe17735f21f733c029d1275e955
ToppCelldroplet-Fat-Mat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR FBN1 LRP1 LTBP3 LTBP4

2.76e-06193515ebd090d7801480b3cee45caac3d30cc991836769
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR FBN1 LRP1 LTBP3 LTBP4

2.76e-0619351522c58032e58730715224d7934968ce92d150b0e8
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKAP6 DLGAP2 DKK1 RET KCNB2

2.76e-06193515a189d46c39067b717509cd144e0225cc93d7731d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 FBN1 ENPP2 FGD5 PKN3

2.76e-061935152e72309607902dabe3218888b22a77fe941f3570
ToppCellfacs-Lung-nan-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBN1 LRP1 LTBP3 LTBP4

2.76e-06193515d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBN1 ENPP2 LRP1 LTBP4

2.76e-06193515428b1a3ad87dff7f65de5161d40f102572a9341b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ENPP2 FGD5 LTBP4 PKN3

2.76e-06193515cc355b2ed6510619cad969ae074126d7c8db784d
ToppCellLA|World / Chamber and Cluster_Paper

FBN1 LRP1 LTBP2 LRP1B PDZRN4

2.76e-06193515d4bf89437216baf489ea0239136dcedf3b6714af
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBN1 ENPP2 LRP1 LTBP4

2.76e-06193515eff718664fe0aaf89050efd9cc7b6dfb1df46666
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 FBN1 FGD5 LTBP4 PKN3

2.76e-061935150b328f725f6feba263783eaca60c142e80df90f3
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR FBN1 LRP1 LTBP3 LTBP4

2.76e-06193515573ad2f848bede1fe20c7b4b352a9242ec294725
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related-FDC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TNFRSF9 DKK1 CD14 LTBP2 ADAM12

2.83e-06194515f9fbb043411546d8c9e0321a64165d411f44aeb7
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

FBN1 LRP1 LTBP2 ADAM12 LTBP4

2.83e-06194515d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 LRP1 LTBP2 ADAM12 LTBP4

2.83e-0619451502b8102be9414d6964cd71019613edff6d88b893
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_progenitor|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 VLDLR FBN1 LTBP3 LTBP4

2.90e-0619551569a29d03e664b72f32d41876510c62345c3aed31
ToppCellCOVID-19-Heart-Low_count_Fib|COVID-19 / Disease (COVID-19 only), tissue and cell type

HSPG2 FBN1 LRP1 LTBP2 LTBP4

2.90e-06195515e09590d1f51d5fa57fceb84c9f48f84b23d4d224
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FBN1 NRXN2 LRP1 LTBP2 LTBP4

2.90e-061955151236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCellfacs-GAT-Fat-3m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 VLDLR FBN1 LTBP3 LTBP4

2.90e-061955151cffae2b08dbfa1c633ce24023e89b66d28b5431
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 FBN1 ENPP2 FGD5 PKN3

2.90e-0619551577e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 VLDLR FBN1 LTBP3 LTBP4

2.90e-061955159cef6f18664518060af7c192310dddce6d70345a
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 NRXN2 ENPP2 LRP1 LTBP4

2.98e-061965156bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 NRXN2 ENPP2 LRP1 LTBP4

2.98e-06196515c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCellfacs-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBN1 LRP1 LTBP3 LTBP4

2.98e-06196515b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCellfacs-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBN1 LRP1 LTBP3 LTBP4

2.98e-06196515787c6cd92035e0b1108c2c086c42a229016e476b
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HSPG2 FBN1 ENPP2 LTBP4 PKN3

3.05e-06197515ad4a3b5da2190be9495382a2952991e1de9f190d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ENPP2 FGD5 LTBP4 PKN3

3.13e-061985155e781583908c4ee107d986904a646a7c6b8e3591
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HSPG2 FGD5 IL4R PKN3 PDZRN4

3.21e-061995153a4deea6e11a0555d27497b7c9983350797aac69
ToppCellmLN-(5)_Dendritic_cell|mLN / shred on region, Cell_type, and subtype

DLGAP2 SLC8A1 NRXN2 ENPP2 RET

3.21e-061995154feecf533e29a1a558f1018a2e8f7bfa7b9d3864
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ENPP2 FGD5 LTBP4 PKN3

3.21e-06199515f35e9c05d0a0339ff691b38564da7aad8e9218aa
ToppCellmLN-Dendritic_cell|mLN / Region, Cell class and subclass

DLGAP2 SLC8A1 NRXN2 ENPP2 RET

3.21e-06199515597412beae1324b9c43ca2bb96c4cb645c19f3e9
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FBN1 LRP1 LTBP2 LTBP3 LTBP4

3.21e-0619951538cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ENPP2 FGD5 LTBP4 PKN3

3.21e-0619951533f1669eeb701986b4dec409efdb6c06c3c41c2b
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FBN1 DKK1 LRP1 LDLR IL4R

3.21e-061995158b86c69aaf60feff53aa782559cfece7342a23de
ToppCellfacs-Trachea-nan-3m-Mesenchymal|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBN1 LRP1 LTBP3 LTBP4

3.21e-0619951567f78c070c56e44fba36542041bf7fa1c291807c
ToppCellfacs-Trachea-nan-3m-Mesenchymal-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 FBN1 LRP1 LTBP3 LTBP4

3.21e-061995151ae244b563f85c1ee8d22698f478c842a4d9c7f5
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

FBN1 DKK1 LRP1 LTBP3 LTBP4

3.28e-062005159d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ENPP2 FGD5 LTBP4 PKN3

3.28e-0620051593e13937ec74418a697c37d56f57509fb2154780
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FBN1 LRP1 LTBP2 LTBP3 LTBP4

3.28e-0620051509537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

FBN1 LRP1 LTBP2 LTBP3 LTBP4

3.28e-06200515a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCellControl-B_naive-4|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FMO4 SCN2A LRP1B IL4R

6.19e-061045145f72aa686b0fb83d401621e1b9d9c69e56105570
ToppCell10x5'-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue

AKAP6 CD14 ENPP2 C9

2.06e-051415147671d300b1722711fd2d8034b96a3aa7e3ccb560
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DLGAP2 TNFRSF9 SCN2A KCNB2

2.12e-05142514819e983688d126d89a71abc03d72525cc759a347
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC8A1 SCN2A RP1L1 LRP1B

2.84e-051535149b6675ace8a83c8d446b722301d0ec4e6840f3fc
ToppCellfacs-Marrow-KLS-18m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 TNFRSF9 ADAM12 SSPOP

2.91e-0515451437765512dfae557b9f6eb30a29463b93682a4404
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC8A1 SCN2A LTBP2 LRP1B

3.22e-051585147960337d87afecf2692ab65e5991f052ceddfacc
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AKAP6 SCN2A LRP1 LRP1B

3.63e-05163514360cd65decda24853124f33a174f5224d7f3ce23
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AKAP6 SCN2A LRP1 LRP1B

3.63e-05163514b59d9b4f7c9f4e5e2c7783a49a96729dae3a81e5
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

VLDLR FBN1 LRP1 KLHL31

3.63e-05163514f1ec2625b52664308968b01d8e0275e1e0751480
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|E18.5-samps / Age Group, Lineage, Cell class and subclass

VLDLR DKK1 LRP1 KLHL31

3.72e-05164514519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

DLGAP2 ENPP2 LRP1 LTBP4

3.90e-0516651465dafed953b01a9830b54309af75c7a561e88336
ToppCellfacs-Trachea-nan-18m-Mesenchymal-chondrocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DKK1 C9 KLHL31 PDZRN4

3.99e-051675147b1fd19946cee67dae68f0f0d98420abcd532482
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DKK1 C9 KLHL31 PDZRN4

3.99e-05167514102b3d160a44c8623fab1fd10e9054178c42a78b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DLGAP2 FBN1 FGD5 LTBP4

4.28e-051705146035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DLGAP2 FBN1 FGD5 LTBP4

4.28e-05170514c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DLGAP2 FBN1 FGD5 LTBP4

4.28e-05170514dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCellfacs-Marrow-T-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8A1 CD14 LRP1 USP9Y

4.28e-05170514a78d9789c3e7c84a36e1bd380192d7aba4a4d443
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 LRP1 ADAM12 LRP1B

4.28e-051705145570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellfacs-Marrow-T-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8A1 CD14 LRP1 USP9Y

4.28e-05170514ff68600b945b3a5437b14e5411b3db800d0ccbe5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 LRP1 LTBP2 LTBP4

4.38e-051715145d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCellfacs-BAT-Fat-3m-Myeloid-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8A1 CD14 LRP1 LDLR

4.48e-051725145f18c3f8eb8b7928901eede44c9b84b3c5efa1a9
ToppCelldroplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 DKK1 FGD5 LTBP4

4.48e-05172514a6fb1bde8d942c7b5caaf7bd14de0b7ce32fda55
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_10|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DLGAP2 TNFRSF9 NRXN2 ADAM12

4.58e-0517351409a13407a41ff2cba82fc417b72bf9a24ce6c42e
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_10|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DLGAP2 TNFRSF9 NRXN2 ADAM12

4.58e-05173514bfec038a6783f166240da4861e100643c6ea80a5
ComputationalMetal / Ca ion binding.

FBN1 LRP1 LTBP2 RET LDLR

6.48e-05133355MODULE_324
ComputationalPlacenta genes.

HSPG2 CD14 HAP1 ENPP2 LRP1 LTBP2 PPP6R2 IL4R

9.39e-05463358MODULE_38
ComputationalOvary genes.

HSPG2 FBN1 CD14 ENPP2 LRP1 LTBP2 LDLR

1.53e-04368357MODULE_1
ComputationalFetal liver genes - metabolism and xenobiotics.

HSPG2 CD14 HAP1 LRP1 PPP6R2 LDLR IL4R

5.43e-04453357MODULE_24
ComputationalGenes in the cancer module 55.

HSPG2 FMO4 CD14 HAP1 ENPP2 LRP1 PPP6R2 LDLR IL4R

1.07e-03832359MODULE_55
ComputationalDRG (dorsal root ganglia) genes.

HSPG2 FBN1 ENPP2 LRP1 LTBP2 LDLR

1.35e-03384356MODULE_2
ComputationalGenes in the cancer module 236.

VLDLR LDLR

1.53e-0318352MODULE_236
Drugmonatepil

LRP12 LRP1 LRP1B LDLR

4.32e-0729494CID000060810
Drugfenoxycarb

LRP12 LRP1 LRP5 C9 LDLR

7.97e-0780495CID000051605
Drugprobucol

VLDLR LRP12 LRP1 LRP5 LRP1B LDLR

1.28e-06162496CID000004912
DrugCS-0398

CD14 LTBP2 LTBP3 LTBP4

2.41e-0644494CID005288149
Drugfuniferine N-oxide

FBN1 LTBP2 LTBP3 LTBP4

3.73e-0649494CID000191631
DrugSorbPC

TNFRSF9 SCN10A

4.54e-062492CID006439169
Drugezetimibe

LRP12 CD14 LRP1 LRP1B LDLR

1.59e-05147495CID000150311
DrugAPETx2 protein, Anthopleura elegantissima

SCN2A SCN10A

2.71e-054492ctd:C501880
Drug4-hydroxybenzylamine

SCN2A LRP5

2.71e-054492CID000097472
DrugN,N-dibenzylphenylethanolamine

LRP12 LRP1

2.71e-054492CID000048896
Drugvitamin E

VLDLR LRP12 LRP1 LRP5 LRP1B LDLR PKN3

4.15e-05441497CID000002116
DrugAC1NAG0I

LTBP2 LTBP3 LTBP4

4.45e-0532493CID004476319
Druggeldanamycin; Up 200; 1uM; MCF7; HT_HG-U133A

VLDLR SCN10A LTBP2 LTBP4 LDLR

4.55e-051834956946_UP
Drugepicholesterol

HSPG2 VLDLR LRP12 HAP1 LRP1 LRP5 LRP1B LDLR

5.82e-05636498CID000000304
Drug2-propylpentanoic acid; Up 200; 200uM; HL60; HT_HG-U133A

TNFRSF9 SCN10A LRP1 DHX57 LTBP2

6.00e-051944956173_UP
DrugCholecalciferol [67-97-0]; Up 200; 10.4uM; MCF7; HT_HG-U133A

LRP12 HAP1 CFAP44 ADAM12 VAV2

6.15e-051954953298_UP
DrugNitrarine dihydrochloride [20069-05-0]; Up 200; 10.6uM; MCF7; HT_HG-U133A

FBN1 SCN10A USP9Y ADAM12 VAV2

6.15e-051954954705_UP
Drug0179445-0000 [211246-22-9]; Up 200; 1uM; MCF7; HT_HG-U133A

LRP12 FBN1 FMO4 SCN10A LTBP4

6.45e-051974954758_UP
DrugMometasone furoate [83919-23-7]; Up 200; 7.6uM; MCF7; HT_HG-U133A

LRP12 SCN10A LRP1 LTBP2 IL4R

6.45e-051974955541_UP
DrugPropranolol hydrochloride [318-98-9]; Up 200; 13.6uM; PC3; HT_HG-U133A

AKAP6 HAP1 LRP1 USP9Y LTBP4

6.45e-051974956759_UP
DrugAtropine sulfate monohydrate [5908-99-6]; Up 200; 5.8uM; MCF7; HT_HG-U133A

HAP1 SCN10A TMPRSS4 LTBP4 VAV2

6.45e-051974952761_UP
DrugPF-00539745-00 [351321-33-0]; Down 200; 10uM; PC3; HT_HG-U133A

FBN1 WEE1 SCN10A LRP1 VAV2

6.45e-051974955939_DN
Drug(+,-)-Octopamine hydrochloride [770-05-8]; Up 200; 21uM; MCF7; HT_HG-U133A

LRP12 SCN10A LRP1 ADAM12 VAV2

6.61e-051984955469_UP
DrugSulfisoxazole [127-69-5]; Up 200; 15uM; PC3; HT_HG-U133A

HSPG2 TNFRSF9 NRXN2 SCN10A TMPRSS4

6.61e-051984954661_UP
DrugParoxetine maleate [64006-44-6]; Up 200; 1uM; PC3; HT_HG-U133A

AKAP6 DLGAP2 TNFRSF9 HAP1 RET

6.77e-051994953821_UP
DrugN-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Up 200; 25.2uM; PC3; HT_HG-U133A

HSPG2 TNFRSF9 SCN10A RET LTBP4

6.77e-051994954311_UP
DrugAPETx1, Anthopleura elegantissima

SCN2A SCN10A

6.77e-056492ctd:C475726
Drugfenpropathrin

SCN2A SCN10A

6.77e-056492ctd:C044267
DrugThiamine hydrochloride [67-03-8]; Up 200; 11.8uM; MCF7; HT_HG-U133A

LRP12 TNFRSF9 HAP1 ADAM12 IL4R

6.93e-052004952894_UP
DrugAntipyrine, 4-hydroxy [1672-63-5]; Down 200; 19.6uM; PC3; HG-U133A

HSPG2 LRP12 FMO4 WEE1 RNF10

6.93e-052004951915_DN
Drugphosphorylcholine

TNFRSF9 CD14 ENPP2 PHRF1 PKN3

7.10e-05201495CID000001014
DrugVanadates

HSPG2 VLDLR SLC8A1 TNFRSF9 USP9X ENPP2 LRP1 LTBP2 LTBP3 USP9Y ADAM12

7.98e-0513024911ctd:D014638
DrugEpi Lovastatin

VLDLR LRP12 LRP1 LRP5 LRP1B LDLR

8.78e-05341496CID000003962
DrugAC1NAL8H

LRP12 LRP1 LDLR

9.43e-0541493CID004478772
Drugethyl lactate

CD14 LRP1

9.46e-057492CID000007344
Drugpitavastatin

LRP12 LRP1 LRP1B LDLR

1.06e-04114494CID005282451
Drugtroglitazone

VLDLR LRP12 WEE1 LRP1 LRP5 LRP1B LDLR

1.25e-04526497CID000005591
Drugtesmilifene

CD14 LRP1

1.26e-048492ctd:C043062
Drug2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate

SCN2A SCN10A

1.26e-048492ctd:C489827
DrugAC1L1J6H

LRP12 LRP1 LRP1B LDLR VAV2

1.51e-04236495CID000004889
Drugbupivacaine

SCN10A LRP5 IL4R PKN3

1.52e-04125494CID000002474
DrugTechnetium-exametazime

HSPG2 SCN2A

2.02e-0410492CID009577951
Diseaseaortic measurement

FBN1 ENPP2 LRP1 FGD5 ADAM12 LTBP4

3.25e-06251486EFO_0020865
DiseaseWeill-Marchesani syndrome

FBN1 LTBP2

7.77e-063482C0265313
DiseaseWeill-Marchesani Syndrome, Autosomal Dominant

FBN1 LTBP2

7.77e-063482C1869115
DiseaseWeill-Marchesani Syndrome, Autosomal Recessive

FBN1 LTBP2

7.77e-063482C1869114
Diseaseinflammatory biomarker measurement

VLDLR SLC8A1 CD14

1.02e-0526483EFO_0004872
DiseaseWeill-Marchesani syndrome

FBN1 LTBP2

1.55e-054482cv:C0265313
DiseaseWeill-Marchesani syndrome (is_implicated_in)

FBN1 LTBP2

1.55e-054482DOID:0050475 (is_implicated_in)
DiseaseFEV/FEC ratio

AKAP6 HSPG2 SLC8A1 FBN1 LRP1 LTBP2 LTBP3 ADAM12 LTBP4 CRB2

2.32e-0512284810EFO_0004713
DiseaseGeleophysic dysplasia

FBN1 LTBP3

2.58e-055482C3489726
DiseaseAcromicric Dysplasia

FBN1 LTBP3

2.58e-055482C0265287
Diseasecholesteryl ester 16:2 measurement

LTBP2 LTBP3

5.41e-057482EFO_0021435
Diseaseobsolete aging

LTBP2 LTBP3 KCNB2 LRP1B PDZRN4

8.95e-05279485GO_0007568
Diseaseaortic aneurysm

FBN1 LRP1

1.16e-0410482EFO_0001666
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN2A SCN10A

1.16e-0410482DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN2A SCN10A

1.16e-0410482DOID:0080422 (implicated_via_orthology)
DiseaseMarfan Syndrome

FBN1 LTBP2

1.41e-0411482C0024796
DiseaseShortened QT interval

SCN10A LRP5

1.41e-0411482C0151879
Diseaseepilepsy (implicated_via_orthology)

SCN2A SCN10A LRP1 LRP1B

1.44e-04163484DOID:1826 (implicated_via_orthology)
DiseaseMitral valve prolapse, response to surgery

LTBP2 LTBP3

1.69e-0412482EFO_0009951, HP_0001634
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN2A SCN10A

1.69e-0412482DOID:0060170 (implicated_via_orthology)
Diseasestenosing tenosynovitis

LTBP2 LTBP3

1.69e-0412482EFO_0010822
DiseaseNon-alcoholic Fatty Liver Disease

VLDLR CD14 LDLR

2.05e-0470483C0400966
DiseaseNonalcoholic Steatohepatitis

VLDLR CD14 LDLR

2.05e-0470483C3241937
Diseaseautosomal dominant polycystic kidney disease (is_marker_for)

CD14 C9

2.33e-0414482DOID:898 (is_marker_for)
DiseaseS-6-hydroxywarfarin measurement

SLC8A1 TMPRSS4 RET KCNB2 VAV2

3.24e-04368485EFO_0803326
DiseaseVan Buchem disease

HSPG2 LRP5

3.47e-0417482C0432272
Diseasecortical thickness

AKAP6 HSPG2 FBN1 ENPP2 LRP1 ADAM12 CRB2 PDZRN4

3.94e-041113488EFO_0004840
Diseasecolorectal cancer

AKAP6 DLGAP2 FBN1 LRP1 CFAP44 VAV2

4.24e-04604486MONDO_0005575
Diseaseperiodontitis

AKAP6 DKK1 SCN2A LRP1B

4.76e-04223484EFO_0000649
Diseasesevere acute respiratory syndrome, COVID-19

DLGAP2 USP9X LTBP2 LTBP3 LRP1B

7.82e-04447485EFO_0000694, MONDO_0100096
Diseasecarotid artery intima media thickness

SLC8A1 FBN1 LRP1 LTBP4 LRP1B

8.05e-04450485EFO_0007117
Diseasemethionine measurement

FMO4 CD14

8.21e-0426482EFO_0009771
DiseaseColorectal Carcinoma

AKAP6 TNFRSF9 LRP1 RET KCNB2 PDZRN4

9.31e-04702486C0009402
Diseasesuicidal ideation

LTBP2 LTBP3

1.02e-0329482EFO_0004320
Diseaserhinitis (is_implicated_in)

CD14 IL4R

1.09e-0330482DOID:4483 (is_implicated_in)
Diseasespontaneous coronary artery dissection

FBN1 LRP1

1.17e-0331482EFO_0010820
Diseasealkaline phosphatase measurement

HSPG2 RP1L1 RNF10 LTBP2 LTBP3 PPP6R2 PDZRN4

1.20e-031015487EFO_0004533
DiseaseAlzheimer's disease (is_implicated_in)

VLDLR LRP1 LDLR

1.31e-03132483DOID:10652 (is_implicated_in)
Diseasedisease recurrence, unipolar depression, bipolar disorder, schizophrenia, sex interaction measurement

ADAM12 LRP1B

1.32e-0333482EFO_0003761, EFO_0004952, EFO_0008343, MONDO_0004985, MONDO_0005090
Diseaseintraocular pressure measurement

LRP12 FBN1 LTBP2 LTBP3 ADAM12

1.39e-03509485EFO_0004695
DiseaseThyroid Gland Follicular Adenoma

ENPP2 RET

1.49e-0335482C0151468
Diseaseascending aortic diameter

FBN1 ENPP2 FGD5

1.55e-03140483EFO_0021787
Diseasepulmonary tuberculosis (is_marker_for)

CD14 IL4R

1.58e-0336482DOID:2957 (is_marker_for)
DiseaseMitral valve prolapse

LTBP2 LTBP3

1.58e-0336482HP_0001634

Protein segments in the cluster

PeptideGeneStartEntry
FVEEGEECDCGEPEE

ADAM12

431

O43184
QCTLCGEPEEEEAGD

DLGAP2

26

Q9P1A6
EDEVFDDSICPTNCD

CFAP44

1531

Q96MT7
YIDSDCIGNPDEDCE

PDZRN4

611

Q6ZMN7
GDFDCEDRTDEANCP

HSPG2

346

P98160
FHCDEESDCPDRSDE

HSPG2

386

P98160
EDDELPEATVGVSCC

KLHL31

596

Q9H511
GNIDCLDLGDEIDCD

LRP12

241

Q9Y561
CDGERDCPDGSDELS

LRP1B

2781

Q9NZR2
CSEEDGPKEEDCSQD

LSG1

321

Q9H089
AGPTCEEDVDECLSD

CRB2

351

Q5IJ48
DCGDGSDEEDCSIDP

LRP1

3766

Q07954
DGFPECDDQSDEEGC

LRP5

1281

O75197
ETATDCPEVLEEGCE

FGD5

266

Q6ZNL6
CVDEDLEPTCFERSD

FMO4

21

P31512
AECPSDDEDLEECEP

NRXN2

1401

Q9P2S2
ASEEEEDPTFCEVCG

PHRF1

176

Q9P1Y6
ECPSDDEDLEECEPS

NRXN2

356

P58401
CQAERDDSDCEEPIE

NRXN2

431

P58401
TPEPCELDDEDFRCV

CD14

21

P08571
CVELFEAPVECEEEE

IL4R

361

P24394
EREGEEFDNTCCPDK

KCNB2

161

Q92953
DEDRCCELPASRDGE

COL20A1

1041

Q9P218
CEDIDECVEEPEICA

FBN1

2011

P35555
LSGEEEDDEPDCCND

DHX57

131

Q6P158
EEEAEEDLQCAHPCD

HAP1

281

P54257
EDGTACEDLDECAFP

LTBP2

1086

Q14767
DSCEDVDECEDPQSS

LTBP2

1131

Q14767
SPESGECVDIDECED

LTBP2

1251

Q14767
DIDECDFPAACIGGD

LTBP3

826

Q9NS15
RLECIDNDECADEEP

LTBP4

1291

Q8N2S1
DNDECADEEPACEGG

LTBP4

1296

Q8N2S1
AEDEECGTDEYCASP

DKK1

86

O94907
DDDCEEIKAAECPAG

ENPP2

146

Q13822
TEPCEDAEDDCGNDF

C9

91

P02748
ACCSDRIQPFDDDED

PPP6R2

621

O75170
ECPFPGDTEEEVFDC

PKN3

756

Q6P5Z2
EPDLEDEQVCCEALE

USP9X

1276

Q93008
ELPHDGTCDECEPDE

TRIM44

11

Q96DX7
CDRQDDCGDGTDEPS

SSPOP

1436

A2VEC9
FEACVEGDSDGEEPC

AKAP6

2156

Q13023
IFSPCSDCEEEEEEE

WEE1

26

P30291
ILEDPFECNDSGEDC

ZNF705A

111

Q6ZN79
QLGEEAEGEEFCPCE

RP1L1

1646

Q8IWN7
DDLEEPDDCFTEGCI

SCN10A

1106

Q9Y5Y9
EGLPEACDDLELADD

RNF10

461

Q8N5U6
PEESLEPEACFTEDC

SCN2A

1161

Q99250
QEEDGCSCRFPEEEE

TNFRSF9

236

Q07011
LCDGELDCPLGEDEE

TMPRSS4

76

Q9NRS4
ACELCPEEEPDDQDA

USP9Y

2471

O00507
ILEDPFECNDSGEDC

ZNF705EP

111

A8MWA4
ILEDPFECNDSGEDC

ZNF705G

111

A8MUZ8
CFPEEEKCFCEPEDI

RET

611

P07949
EHDLGEDIYDCVPCE

VAV2

151

P52735
QDDCSDGSDELDCAP

VLDLR

176

P98155
DRDCLDGSDEASCPV

LDLR

131

P01130
DDDECGEEKLPSCFD

SLC8A1

761

P32418