Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein kinase A binding	EZR RDX AKAP9	1.19e-04	58	33	3	GO:0051018
GeneOntologyBiologicalProcess	positive regulation of early endosome to late endosome transport	EZR RDX	9.43e-05	9	34	2	GO:2000643
GeneOntologyBiologicalProcess	microtubule nucleation	RANBP9 AKAP9 NME7	1.13e-04	57	34	3	GO:0007020
GeneOntologyBiologicalProcess	regulation of protein localization to early endosome	EZR RDX	1.18e-04	10	34	2	GO:1902965
GeneOntologyBiologicalProcess	positive regulation of protein localization to early endosome	EZR RDX	1.18e-04	10	34	2	GO:1902966
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	RANBP9 EZR CCP110 SPECC1L AKAP9 NME7 CFAP46	1.45e-04	720	34	7	GO:0000226
GeneOntologyBiologicalProcess	microtubule polymerization or depolymerization	RANBP9 SPECC1L AKAP9 NME7	1.63e-04	168	34	4	GO:0031109
GeneOntologyBiologicalProcess	protein polymerization	RANBP9 RDX AKAP9 NME7 GPX4	2.04e-04	334	34	5	GO:0051258
GeneOntologyBiologicalProcess	positive regulation of protein localization to endosome	EZR RDX	2.37e-04	14	34	2	GO:1905668
GeneOntologyBiologicalProcess	microtubule-based process	RANBP9 EZR CCP110 SPECC1L AKAP9 KLC4 NME7 CFAP46	2.57e-04	1058	34	8	GO:0007017
GeneOntologyBiologicalProcess	regulation of protein localization to endosome	EZR RDX	2.73e-04	15	34	2	GO:1905666
GeneOntologyBiologicalProcess	protein localization to early endosome	EZR RDX	3.12e-04	16	34	2	GO:1902946
GeneOntologyBiologicalProcess	regulation of early endosome to late endosome transport	EZR RDX	4.92e-04	20	34	2	GO:2000641
GeneOntologyBiologicalProcess	regulation of cell size	EZR RDX AKT3 SPP1	4.95e-04	225	34	4	GO:0008361
GeneOntologyBiologicalProcess	retinal metabolic process	ABCA4 BCO1	5.43e-04	21	34	2	GO:0042574
GeneOntologyCellularComponent	cell tip	EZR RDX	3.44e-04	17	34	2	GO:0051286
GeneOntologyCellularComponent	cluster of actin-based cell projections	TRPM6 EZR RDX CA4	4.55e-04	223	34	4	GO:0098862
GeneOntologyCellularComponent	cell pole	EZR RDX	4.79e-04	20	34	2	GO:0060187
GeneOntologyCellularComponent	cilium	EZR CCP110 ABCA4 AKAP9 NME7 CFAP46 CC2D2B	5.13e-04	898	34	7	GO:0005929
Domain	ERM_C_dom	EZR RDX	1.60e-05	4	31	2	IPR011259
Domain	ERM	EZR RDX	1.60e-05	4	31	2	IPR011174
Domain	ERM	EZR RDX	1.60e-05	4	31	2	PF00769
Domain	Moesin_tail	EZR RDX	5.57e-05	7	31	2	IPR008954
Domain	Ez/rad/moesin-like	EZR RDX	5.49e-04	21	31	2	IPR000798
Domain	FERM_CS	EZR RDX	7.19e-04	24	31	2	IPR019747
Domain	FERM_C	EZR RDX	8.45e-04	26	31	2	PF09380
Domain	FERM_C	EZR RDX	9.12e-04	27	31	2	SM01196
Domain	FERM_PH-like_C	EZR RDX	9.12e-04	27	31	2	IPR018980
Domain	FERM_N	EZR RDX	1.36e-03	33	31	2	IPR018979
Domain	FERM_N	EZR RDX	1.36e-03	33	31	2	PF09379
Domain	KH_1	ANKRD17 ANKHD1	1.81e-03	38	31	2	PF00013
Domain	KH	ANKRD17 ANKHD1	2.00e-03	40	31	2	SM00322
Domain	KH_dom	ANKRD17 ANKHD1	2.00e-03	40	31	2	IPR004087
Domain	KH_TYPE_1	ANKRD17 ANKHD1	2.20e-03	42	31	2	PS50084
Domain	KH_dom_type_1	ANKRD17 ANKHD1	2.42e-03	44	31	2	IPR004088
Domain	FERM_M	EZR RDX	2.64e-03	46	31	2	PF00373
Domain	FERM_central	EZR RDX	2.99e-03	49	31	2	IPR019748
Domain	FERM_domain	EZR RDX	2.99e-03	49	31	2	IPR000299
Domain	-	EZR RDX	2.99e-03	49	31	2	1.20.80.10
Domain	FERM_1	EZR RDX	3.11e-03	50	31	2	PS00660
Domain	FERM_2	EZR RDX	3.11e-03	50	31	2	PS00661
Domain	Band_41_domain	EZR RDX	3.11e-03	50	31	2	IPR019749
Domain	B41	EZR RDX	3.11e-03	50	31	2	SM00295
Domain	FERM/acyl-CoA-bd_prot_3-hlx	EZR RDX	3.11e-03	50	31	2	IPR014352
Domain	FERM_3	EZR RDX	3.11e-03	50	31	2	PS50057
Domain	Ubiquitin-rel_dom	EZR RDX RIN2	3.45e-03	184	31	3	IPR029071
Domain	DEAD	BLM EIF4A1	6.51e-03	73	31	2	PF00270
Domain	DEAD/DEAH_box_helicase_dom	BLM EIF4A1	6.51e-03	73	31	2	IPR011545
Pubmed	Perspectives for Ezrin and Radixin in Astrocytes: Kinases, Functions and Pathology.	EZR RDX	9.28e-07	2	34	2	31382374
Pubmed	Emerging role for ERM proteins in cell adhesion and migration.	EZR RDX	9.28e-07	2	34	2	21343695
Pubmed	Radixin is a novel member of the band 4.1 family.	EZR RDX	9.28e-07	2	34	2	1955455
Pubmed	Mapping of ezrin dimerization using yeast two-hybrid screening.	EZR RDX	9.28e-07	2	34	2	9501018
Pubmed	The ezrin-like family of tyrosine kinase substrates: receptor-specific pattern of tyrosine phosphorylation and relationship to malignant transformation.	EZR RDX	2.78e-06	3	34	2	8479753
Pubmed	Characterization of lens fiber cell triton insoluble fraction reveals ERM (ezrin, radixin, moesin) proteins as major cytoskeletal-associated proteins.	EZR RDX	2.78e-06	3	34	2	18261459
Pubmed	Ezrin, radixin, and moesin are phosphorylated in response to 2-methoxyestradiol and modulate endothelial hyperpermeability.	EZR RDX	2.78e-06	3	34	2	21659656
Pubmed	Expression, localization, and binding activity of the ezrin/radixin/moesin proteins in the mouse testis.	EZR RDX	2.78e-06	3	34	2	19064715
Pubmed	Regulation of ErbB2 localization and function in breast cancer cells by ERM proteins.	EZR RDX	2.78e-06	3	34	2	27029001
Pubmed	Activation of PKC induces leukocyte adhesion by the dephosphorylation of ERM.	EZR RDX	2.78e-06	3	34	2	31843195
Pubmed	Differential involvement of ezrin/radixin/moesin proteins in sphingosine 1-phosphate-induced human pulmonary endothelial cell barrier enhancement.	EZR RDX	2.78e-06	3	34	2	21864676
Pubmed	Differential expression of ezrin/radixin/moesin (ERM) and ERM-associated adhesion molecules in the blastocyst and uterus suggests their functions during implantation.	EZR RDX	2.78e-06	3	34	2	14613898
Pubmed	Increased phosphorylation of ezrin/radixin/moesin proteins contributes to proliferation of rheumatoid fibroblast-like synoviocytes.	EZR RDX	2.78e-06	3	34	2	21278069
Pubmed	Inhibition of cell adhesion by phosphorylated Ezrin/Radixin/Moesin.	EZR RDX	2.78e-06	3	34	2	26555866
Pubmed	Human ezrin-moesin-radixin proteins modulate hepatitis C virus infection.	EZR RDX	2.78e-06	3	34	2	23703860
Pubmed	Pseudomonas aeruginosa ExoS ADP-ribosyltransferase inhibits ERM phosphorylation.	EZR RDX	2.78e-06	3	34	2	16889625
Pubmed	Nuclear ERM (ezrin, radixin, moesin) proteins: regulation by cell density and nuclear import.	EZR RDX	2.78e-06	3	34	2	15149851
Pubmed	Effect of knockdown of ezrin, radixin, and moesin on P-glycoprotein function in HepG2 cells.	EZR RDX	2.78e-06	3	34	2	21837648
Pubmed	ERM stable knockdown by siRNA reduced in vitro migration and invasion of human SGC-7901 cells.	EZR RDX	2.78e-06	3	34	2	21352885
Pubmed	Ezrin and moesin function together to promote T cell activation.	EZR RDX	2.78e-06	3	34	2	19124745
Pubmed	A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sites.	EZR RDX	2.78e-06	3	34	2	1429901
Pubmed	ERM Proteins at the Crossroad of Leukocyte Polarization, Migration and Intercellular Adhesion.	EZR RDX	2.78e-06	3	34	2	32098334
Pubmed	Ezrin, Radixin, and Moesin (ERM) proteins function as pleiotropic regulators of human immunodeficiency virus type 1 infection.	EZR RDX	2.78e-06	3	34	2	18295815
Pubmed	Dmoesin controls actin-based cell shape and polarity during Drosophila melanogaster oogenesis.	EZR RDX	2.78e-06	3	34	2	12360288
Pubmed	Activation of Ras requires the ERM-dependent link of actin to the plasma membrane.	EZR RDX	2.78e-06	3	34	2	22132106
Pubmed	Dynamics and function of ERM proteins during cytokinesis in human cells.	EZR RDX	2.78e-06	3	34	2	28889652
Pubmed	Ezrin and radixin both regulate the apical membrane localization of ABCC2 (MRP2) in human intestinal epithelial Caco-2 cells.	EZR RDX	2.78e-06	3	34	2	17825285
Pubmed	Control of adipogenesis by ezrin, radixin and moesin-dependent biomechanics remodeling.	EZR RDX	2.78e-06	3	34	2	23116763
Pubmed	Induction of ezrin-radixin-moesin molecules after cryogenic traumatic brain injury of the mouse cortex.	EZR RDX	2.78e-06	3	34	2	21451358
Pubmed	Mask family proteins ANKHD1 and ANKRD17 regulate YAP nuclear import and stability.	ANKRD17 ANKHD1	2.78e-06	3	34	2	31661072
Pubmed	Ezrin-radixin-moesin family proteins are involved in parvovirus replication and spreading.	EZR RDX	2.78e-06	3	34	2	19321616
Pubmed	A-Kinase Anchoring Proteins Diminish TGF-β1/Cigarette Smoke-Induced Epithelial-To-Mesenchymal Transition.	EZR AKAP9	2.78e-06	3	34	2	32028718
Pubmed	Deciphering brain-specific transcriptomic expression of Ezr, Rad and Msn genes in the development of Mus musculus.	EZR RDX	2.78e-06	3	34	2	29906485
Pubmed	Differential effects of ceramide and sphingosine 1-phosphate on ERM phosphorylation: probing sphingolipid signaling at the outer plasma membrane.	EZR RDX	2.78e-06	3	34	2	20679347
Pubmed	Differential expression and distribution of ezrin, radixin and moesin in human natural killer cells.	EZR RDX	2.78e-06	3	34	2	12385025
Pubmed	Are ERM (ezrin/radixin/moesin) proteins targets for autoantibodies in demyelinating neuropathies?	EZR RDX	2.78e-06	3	34	2	25286001
Pubmed	Osmotic cell shrinkage activates ezrin/radixin/moesin (ERM) proteins: activation mechanisms and physiological implications.	EZR RDX	2.78e-06	3	34	2	17977945
Pubmed	Ezrin/radixin/moesin proteins are high affinity targets for ADP-ribosylation by Pseudomonas aeruginosa ExoS.	EZR RDX	2.78e-06	3	34	2	15252013
Pubmed	ERM-Dependent Assembly of T Cell Receptor Signaling and Co-stimulatory Molecules on Microvilli prior to Activation.	EZR RDX	2.78e-06	3	34	2	32160548
Pubmed	The amino-terminal domains of the ezrin, radixin, and moesin (ERM) proteins bind advanced glycation end products, an interaction that may play a role in the development of diabetic complications.	EZR RDX	2.78e-06	3	34	2	12734202
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RANBP9 BLM RLF DKC1 ANKRD17 PSMD2 NME7 ANKHD1 EIF4A1	4.32e-06	1353	34	9	29467282
Pubmed	Functional binding interaction identified between the axonal CAM L1 and members of the ERM family.	EZR RDX	5.56e-06	4	34	2	12070130
Pubmed	CPI-17 drives oncogenic Ras signaling in human melanomas via Ezrin-Radixin-Moesin family proteins.	EZR RDX	5.56e-06	4	34	2	27793041
Pubmed	The NHE1 Na+/H+ exchanger recruits ezrin/radixin/moesin proteins to regulate Akt-dependent cell survival.	EZR RDX	5.56e-06	4	34	2	15096511
Pubmed	Gene fusion and overlapping reading frames in the mammalian genes for 4E-BP3 and MASK.	ANKRD17 ANKHD1	5.56e-06	4	34	2	14557257
Pubmed	Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis.	EZR RDX	5.56e-06	4	34	2	19890007
Pubmed	The lipid 5-phoshatase SHIP2 controls renal brush border ultrastructure and function by regulating the activation of ERM proteins.	EZR RDX	5.56e-06	4	34	2	28302370
Pubmed	Anoctamin 1 (Tmem16A) Ca2+-activated chloride channel stoichiometrically interacts with an ezrin-radixin-moesin network.	EZR RDX	5.56e-06	4	34	2	22685202
Pubmed	Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein.	EZR RDX	5.56e-06	4	34	2	9287351
Pubmed	CD43 interaction with ezrin-radixin-moesin (ERM) proteins regulates T-cell trafficking and CD43 phosphorylation.	EZR RDX	5.56e-06	4	34	2	21289089
Pubmed	Phosphorylated ERM is responsible for increased T cell polarization, adhesion, and migration in patients with systemic lupus erythematosus.	EZR RDX	5.56e-06	4	34	2	17237445
Pubmed	The ERM proteins interact with the HOPS complex to regulate the maturation of endosomes.	EZR RDX	5.56e-06	4	34	2	21148287
Pubmed	Rho-ROCK-dependent ezrin-radixin-moesin phosphorylation regulates Fas-mediated apoptosis in Jurkat cells.	EZR RDX	5.56e-06	4	34	2	18941185
Pubmed	Mutagenesis of the ezrin-radixin-moesin binding domain of L-selectin tail affects shedding, microvillar positioning, and leukocyte tethering.	EZR RDX	5.56e-06	4	34	2	15178693
Pubmed	Cortical mechanics and meiosis II completion in mammalian oocytes are mediated by myosin-II and Ezrin-Radixin-Moesin (ERM) proteins.	EZR RDX	5.56e-06	4	34	2	20660156
Pubmed	In Vitro and in Vivo Characterization of Molecular Interactions between Calmodulin, Ezrin/Radixin/Moesin, and L-selectin.	EZR RDX	5.56e-06	4	34	2	19129194
Pubmed	Human immunodeficiency virus (HIV)-1 proteins and cytoskeleton: partners in viral life and host cell death.	EZR RDX	5.56e-06	4	34	2	15818415
Pubmed	Two Sides of the Coin: Ezrin/Radixin/Moesin and Merlin Control Membrane Structure and Contact Inhibition.	EZR RDX	5.56e-06	4	34	2	31018575
Pubmed	Ezrin is a component of the HIV-1 virological presynapse and contributes to the inhibition of cell-cell fusion.	EZR RDX	5.56e-06	4	34	2	24760896
Pubmed	Proteomic profiling in pancreatic cancer with and without lymph node metastasis.	EZR RDX	5.56e-06	4	34	2	19152423
Pubmed	LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation.	EZR RDX	5.56e-06	4	34	2	19255442
Pubmed	Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout.	EZR RDX	5.56e-06	4	34	2	9890997
Pubmed	Spatial regulation of cyclic AMP-Epac1 signaling in cell adhesion by ERM proteins.	EZR RDX	5.56e-06	4	34	2	20855527
Pubmed	Interplay between RAGE, CD44, and focal adhesion molecules in epithelial-mesenchymal transition of alveolar epithelial cells.	EZR RDX	9.26e-06	5	34	2	21278261
Pubmed	Ezrin/radixin/moesin are required for the purinergic P2X7 receptor (P2X7R)-dependent processing of the amyloid precursor protein.	EZR RDX	9.26e-06	5	34	2	22891241
Pubmed	The TSC1 tumour suppressor hamartin regulates cell adhesion through ERM proteins and the GTPase Rho.	EZR RDX	9.26e-06	5	34	2	10806479
Pubmed	Vitronectin induces phosphorylation of ezrin/radixin/moesin actin-binding proteins through binding to its novel neuronal receptor telencephalin.	EZR RDX	9.26e-06	5	34	2	23019340
Pubmed	Sensitivity of CYP1A1 mRNA inducibility by dioxin is the same in Cyp1a2(+/+) wild-type and Cyp1a2(-/-) null mutant mice.	EZR RDX	9.26e-06	5	34	2	9464455
Pubmed	Activated ERM protein plays a critical role in drug resistance of MOLT4 cells induced by CCL25.	EZR RDX	9.26e-06	5	34	2	23326330
Pubmed	Regulation of NK cell trafficking by CD81.	EZR RDX	9.26e-06	5	34	2	19830727
Pubmed	Anchoring of protein kinase A by ERM (ezrin-radixin-moesin) proteins is required for proper netrin signaling through DCC (deleted in colorectal cancer).	EZR RDX	9.26e-06	5	34	2	25575591
Pubmed	A Pak1-PP2A-ERM signaling axis mediates F-actin rearrangement and degranulation in mast cells.	EZR RDX	9.26e-06	5	34	2	23063725
Pubmed	A novel role for BRCA1 in regulating breast cancer cell spreading and motility.	EZR RDX	9.26e-06	5	34	2	21282464
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	EZR DKC1 ANKRD17 PSMD2 ANKHD1 EIF4A1	1.24e-05	538	34	6	28524877
Pubmed	Human immunodeficiency virus (HIV-1) Vpr induced downregulation of NHE1 induces alteration in intracellular pH and loss of ERM complex in target cells.	EZR RDX	1.39e-05	6	34	2	17349711
Pubmed	Intracellular sphingosine kinase 2-derived sphingosine-1-phosphate mediates epidermal growth factor-induced ezrin-radixin-moesin phosphorylation and cancer cell invasion.	EZR RDX	1.39e-05	6	34	2	26209696
Pubmed	CLIC5 stabilizes membrane-actin filament linkages at the base of hair cell stereocilia in a molecular complex with radixin, taperin, and myosin VI.	EZR RDX	1.39e-05	6	34	2	24285636
Pubmed	Gene expression in temporal lobe epilepsy is consistent with increased release of glutamate by astrocytes.	EZR RDX	1.39e-05	6	34	2	17515952
Pubmed	Expression of ezrin in subventricular zone neural stem cells and their progeny in adult and developing mice.	EZR RDX	1.39e-05	6	34	2	23229862
Pubmed	Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2.	EZR RDX	1.39e-05	6	34	2	9472040
Pubmed	A novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells.	DKC1 CLK4 EIF4A1	1.72e-05	51	34	3	34316707
Pubmed	HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.	RANBP9 PSMD2 NME7 ANKHD1 ODR4 EIF4A1	1.74e-05	571	34	6	37167062
Pubmed	MYADM controls endothelial barrier function through ERM-dependent regulation of ICAM-1 expression.	EZR RDX	1.94e-05	7	34	2	23264465
Pubmed	Generation of functional liver organoids on combining hepatocytes and cholangiocytes with hepatobiliary connections ex vivo.	EZR SPP1	1.94e-05	7	34	2	34099675
Pubmed	Adaptor protein cerebral cavernous malformation 3 (CCM3) mediates phosphorylation of the cytoskeletal proteins ezrin/radixin/moesin by mammalian Ste20-4 to protect cells from oxidative stress.	EZR RDX	1.94e-05	7	34	2	22291017
Pubmed	CP110 cooperates with two calcium-binding proteins to regulate cytokinesis and genome stability.	CCP110 AKAP9	2.59e-05	8	34	2	16760425
Pubmed	VIP regulates CFTR membrane expression and function in Calu-3 cells by increasing its interaction with NHERF1 and P-ERM in a VPAC1- and PKCε-dependent manner.	EZR RDX	2.59e-05	8	34	2	24788249
Pubmed	Finding the Unicorn, a New Mouse Model of Midfacial Clefting.	EZR RDX	3.33e-05	9	34	2	31940751
Pubmed	Radixin regulates cell migration and cell-cell adhesion through Rac1.	EZR RDX	3.33e-05	9	34	2	22467863
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	RANBP9 EZR ANKRD17 RDX SPECC1L AKAP9 EIF4A1	3.42e-05	963	34	7	28671696
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	ANKRD17 RDX TAOK3 ANKHD1 EIF4A1 SEMA3E	3.59e-05	650	34	6	38777146
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	EZR DKC1 RDX SPECC1L EIF4A1 EFR3A	3.90e-05	660	34	6	32780723
Pubmed	Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes.	EZR RDX	4.15e-05	10	34	2	12068294
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	RANBP9 EZR DKC1 ANKRD17 RDX PSMD2 GPX4	4.48e-05	1005	34	7	19615732
Pubmed	Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.	EZR ANKRD17 RDX ANKHD1	5.69e-05	215	34	4	35973513
Pubmed	Alpha6beta4 integrin and dystroglycan cooperate to stabilize the myelin sheath.	EZR RDX	6.08e-05	12	34	2	18579745
Pubmed	Podoplanin regulates mammary stem cell function and tumorigenesis by potentiating Wnt/β-catenin signaling.	EZR RDX	6.08e-05	12	34	2	29361573
Pubmed	Inhibition of T cell activation by cyclic adenosine 5'-monophosphate requires lipid raft targeting of protein kinase A type I by the A-kinase anchoring protein ezrin.	EZR AKAP9	6.08e-05	12	34	2	17911601
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	BLM EZR RDX PSMD2 ZZZ3	6.80e-05	444	34	5	34795231
Pubmed	Embryo-uterine interaction coordinates mouse embryogenesis during implantation.	EZR RDX	7.19e-05	13	34	2	37522872
Interaction	AKR1B1 interactions	BLM EZR RDX GPX4	1.02e-05	81	34	4	int:AKR1B1
Interaction	CEP43 interactions	BLM ANKRD17 SPECC1L AKAP9 KLC4	1.57e-05	190	34	5	int:CEP43
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	EZR AKAP9	7.28e-04	29	25	2	396
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	EZR RDX	2.16e-03	50	25	2	1293
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	KLC4 CFAP46	1.09e-02	115	25	2	769
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	BLM RLF ANKRD17 RDX TAOK3 SPECC1L ZZZ3 AKAP9 RIN2 EFR3A	8.43e-08	856	34	10	M4500
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	BLM RLF RDX TAOK3 ZZZ3 ANKHD1 SPP1	1.78e-05	656	34	7	M18979
Coexpression	ITO_PTTG1_TARGETS_DN	PSMD2 EIF4A1	5.85e-05	9	34	2	M2292
Coexpression	GSE23321_CD8_STEM_CELL_MEMORY_VS_NAIVE_CD8_TCELL_UP	PSMD2 ANKHD1 ODR4 EIF4A1	1.23e-04	198	34	4	M8440
Coexpression	GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA5_STIM_CD8_TCELL_UP	RANBP9 TAOK3 ZZZ3 RIN2	1.28e-04	200	34	4	M8050
Coexpression	GSE24634_NAIVE_CD4_TCELL_VS_DAY10_IL4_CONV_TREG_DN	BLM RDX TAOK3 SPP1	1.28e-04	200	34	4	M4597
Coexpression	GSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_DN	DKC1 TAOK3 ZZZ3 RIN2	1.28e-04	200	34	4	M4538
Coexpression	GSE27786_CD4_TCELL_VS_NKCELL_UP	RLF ABCA4 ZZZ3 AKAP9	1.28e-04	200	34	4	M4822
Coexpression	GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY7_UP	RLF RDX AKAP9 ANKHD1	1.28e-04	200	34	4	M6584
Coexpression	GSE27786_LIN_NEG_VS_CD8_TCELL_DN	RANBP9 RLF TAOK3 EFR3A	1.28e-04	200	34	4	M4777
Coexpression	GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_DN	RDX NME7 SPP1 GPX4	1.28e-04	200	34	4	M4459
Coexpression	CHEN_HOXA5_TARGETS_9HR_UP	RLF ZZZ3 ODR4 CLK4	1.94e-04	223	34	4	M17621
Disease	D dimer measurement	ABCA4 NME7	5.49e-04	30	34	2	EFO_0004507
Disease	S-6-hydroxywarfarin measurement	TMEM196 ABCA4 ODR4 SEMA3E	8.21e-04	368	34	4	EFO_0803326
Disease	retinitis pigmentosa (is_implicated_in)	ABCA4 CA4	1.03e-03	41	34	2	DOID:10584 (is_implicated_in)
Disease	cognitive inhibition measurement	TRPM6 AKT3	1.52e-03	50	34	2	EFO_0007969
Disease	parathyroid hormone measurement	RDX RIN2	1.84e-03	55	34	2	EFO_0004752

Protein segments in the cluster

Peptide	Gene	Start	Entry
HLEMMESELAGKQHE	AKAP9	156	Q99996
EMEAMLEDTGLHHKR	ABCA4	1041	P78363
DHETTMACAHRALEM	CFAP46	951	Q8IYW2
QEMIGALKERSHHME	SPECC1L	531	Q69YQ0
DQEHKTDEMHTALME	ANKRD17	426	O75179
NIFDEMMTEKHEDHC	CC2D2B	971	Q6DHV5
EVMHNLMDRHDNRAK	EFR3A	481	Q14156
EEMDASTTHHKRKTM	AKT3	131	Q9Y243
KHDHEMEDCDTEMEV	RANBP9	586	Q96S59
SKSNESHDHMDDMDD	SPP1	76	P10451
HEEHRGMLREDSMME	RDX	176	P35241
MHAEEREEMSKSRHH	KLC4	426	Q9NSK0
KMHARDFTVSAMHGD	EIF4A1	291	P60842
SAEEIRDHFMEMLDH	ODR4	366	Q5SWX8
MMEKDGNHHTRETHF	BLM	1006	P54132
SEHSLDGEHFAMEMH	CA4	126	P22748
VMDAAERMSILHHDR	CCP110	876	O43303
HAEHRGMLKDNAMLE	EZR	176	P15311
VFQTHDSKEHLAMME	CLK4	376	Q9HAZ1
MHEFSAKDIDGHMVN	GPX4	41	P36969
EFKMERGEVMDTSHH	C4orf54	826	D6RIA3
EKDHMVTMHDVLDAQ	DKC1	256	O60832
AHMADMEAKYEEILH	CCDC153	146	Q494R4
MMLSRKEALDFHVDH	NME7	126	Q9Y5B8
MDAHKGAEMFRRVHV	NUBPL	216	Q8TB37
MAHNAEHEACDLLME	PSMD2	196	Q13200
QKEMEHAMLIRHDES	TAOK3	641	Q9H2K8
ARASVDVDMHMDLHG	BCO1	501	Q9HAY6
ADQEHKTDEMHTALM	ANKHD1	396	Q8IWZ3
HVEAMLKDFHMADGS	RIN2	606	Q8WYP3
HHSHEMAEKEITDNM	TMEM196	151	Q5HYL7
RAMAHEAKESHMVDD	TRPM6	646	Q9BX84
EARILHHSKMHMEDG	RLF	566	Q13129
MFNKDDEEDRHHRMP	SEMA3E	681	O15041
MDEDDDRSCFHSHMN	ZZZ3	756	Q8IYH5