Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentsomatodendritic compartment

ACSL4 GABRG3 DLGAP2 RELN TRPM5 CSNK1E KIF1B VPS13A KCNQ3 CNKSR2 INPP5F GRM3 DYNC1H1 ADCY9 STAT1

2.55e-0412289115GO:0036477
GeneOntologyCellularComponentsperm flagellum

TCP11X1 LYZL4 TCP11X2 DNAH17 VPS13A CFAP65

3.47e-04214916GO:0036126
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

ACSL4 FMO4 ERP44 MSMO1 VPS13A GPAT3 UGT2B10 PORCN DHDDS ELOVL6 RNF139 TRAPPC2B ADGRG6 ITPR2 TRAPPC2

5.79e-0413279115GO:0042175
GeneOntologyCellularComponent9+2 motile cilium

TCP11X1 LYZL4 TCP11X2 DNAH17 VPS13A CFAP65

6.08e-04238916GO:0097729
GeneOntologyCellularComponentnuclear outer membrane

UGT2B10 TRAPPC2B TRAPPC2

7.02e-0440913GO:0005640
GeneOntologyCellularComponentlysosome

NPC1 ATP8A1 MAN2B1 VPS13A SIDT1 CTNS ENPEP PLBD2 ANKRD27 DYNC1H1 IFNAR1

7.84e-048119111GO:0005764
GeneOntologyCellularComponentlytic vacuole

NPC1 ATP8A1 MAN2B1 VPS13A SIDT1 CTNS ENPEP PLBD2 ANKRD27 DYNC1H1 IFNAR1

7.84e-048119111GO:0000323
GeneOntologyCellularComponentTRAPPII protein complex

TRAPPC2B TRAPPC2

1.20e-0312912GO:1990071
GeneOntologyCellularComponentTRAPPIII protein complex

TRAPPC2B TRAPPC2

1.20e-0312912GO:1990072
GeneOntologyCellularComponentorganelle outer membrane

ACSL4 MYOC VPS13A UGT2B10 TRAPPC2B TRAPPC2

1.38e-03279916GO:0031968
GeneOntologyCellularComponentouter membrane

ACSL4 MYOC VPS13A UGT2B10 TRAPPC2B TRAPPC2

1.43e-03281916GO:0019867
GeneOntologyCellularComponentaxon

RELN MYOC CSNK1E KIF1B KCNQ3 INPP5F GRM3 DYNC1H1 ADCY9 STAT1 ITPR2

1.67e-038919111GO:0030424
GeneOntologyCellularComponentvacuole

NPC1 ATP8A1 MAN2B1 VPS13A SIDT1 CTNS ENPEP PLBD2 ANKRD27 DYNC1H1 IFNAR1

2.02e-039139111GO:0005773
DomainEF-hand_7

VSNL1 DGKG MACF1 EFHB HPCAL4

5.62e-0585905PF13499
DomainSAPS

PPP6R2 PPP6R3

6.87e-053902IPR007587
DomainSAPS

PPP6R2 PPP6R3

6.87e-053902PF04499
Domain-

VSNL1 DGKG MACF1 PLCL1 EFHB HPCAL4 STAT1

2.67e-042619071.10.238.10
Pubmed

IDO1+ Paneth cells promote immune escape of colorectal cancer.

IDO1 STAT1 IFNAR1

7.63e-08494332444775
Pubmed

Serotonin reduction in post-acute sequelae of viral infection.

IDO1 STAT1 IFNAR1

1.90e-07594337848036
Pubmed

Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.

RELN KCNQ3 GRM3 ADCY9

6.85e-064594425979088
Pubmed

Cutting edge: CpG oligonucleotides induce splenic CD19+ dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN Type 1 signaling.

IDO1 IFNAR1

7.23e-06294216237046
Pubmed

Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38.

STAT1 IFNAR1

7.23e-06294239002130
Pubmed

SNP-PCR genotyping links alterations in the GABAA receptor (GABRG3: rs208129) and RELN (rs73670) genes to autism spectrum disorder among peadiatric Iraqi Arabs.

GABRG3 RELN

7.23e-06294235403940
Pubmed

Interferon alpha receptors and STAT1 as therapy predictors of a sustained virological response in hepatitis C/B co-infection.

STAT1 IFNAR1

7.23e-06294230410131
Pubmed

Isolation of two human cDNAs, HLP3 and HLP4, homologous to the neuron-specific calcium-binding protein genes.

VSNL1 HPCAL4

7.23e-06294210520747
Pubmed

Protective neutralizing antibodies from human survivors of Crimean-Congo hemorrhagic fever.

STAT1 IFNAR1

7.23e-06294234077751
Pubmed

Promotion of alpha/beta interferon induction during in vivo viral infection through alpha/beta interferon receptor/STAT1 system-dependent and -independent pathways.

STAT1 IFNAR1

7.23e-06294211932417
Pubmed

Curcumin combined with FAPαc vaccine elicits effective antitumor response by targeting indolamine-2,3-dioxygenase and inhibiting EMT induced by TNF-α in melanoma.

FAP IDO1

7.23e-06294226305550
Pubmed

Unique signatures of long noncoding RNA expression in response to virus infection and altered innate immune signaling.

STAT1 IFNAR1

7.23e-06294220978541
Pubmed

Immunosuppressive CD14+HLA-DRlow/neg IDO+ myeloid cells in patients following allogeneic hematopoietic stem cell transplantation.

IDO1 STAT1

7.23e-06294222828446
Pubmed

Mice lacking functional STAT1 are highly susceptible to lethal infection with Lassa virus.

STAT1 IFNAR1

7.23e-06294223903830
Pubmed

Human wild-type SEDL protein functionally complements yeast Trs20p but some naturally occurring SEDL mutants do not.

TRAPPC2B TRAPPC2

7.23e-06294214597397
Pubmed

Identification of the gene (SEDL) causing X-linked spondyloepiphyseal dysplasia tarda.

TRAPPC2B TRAPPC2

7.23e-06294210431248
Pubmed

Requirement for STAT1 in LPS-induced gene expression in macrophages.

STAT1 IFNAR1

7.23e-06294211310846
Pubmed

STAT1 signaling in CD8 T cells is required for their clonal expansion and memory formation following viral infection in vivo.

STAT1 IFNAR1

7.23e-06294218250422
Pubmed

Type I IFN receptor regulates neutrophil functions and innate immunity to Leishmania parasites.

STAT1 IFNAR1

7.23e-06294220483775
Pubmed

Spondyloepiphyseal dysplasia tarda (SEDL, MIM #313400).

TRAPPC2B TRAPPC2

7.23e-06294212939648
Pubmed

A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells.

STAT1 IFNAR1

7.23e-06294215851485
Pubmed

Inhibition of the Na+/K+-ATPase by cardiac glycosides suppresses expression of the IDO1 immune checkpoint in cancer cells by reducing STAT1 activation.

IDO1 STAT1

7.23e-06294235150740
Pubmed

Differential regulation of constitutive major histocompatibility complex class I expression in T and B lymphocytes.

STAT1 IFNAR1

2.16e-05394210562320
Pubmed

Caspase-mediated cleavage of murine norovirus NS1/2 potentiates apoptosis and is required for persistent infection of intestinal epithelial cells.

STAT1 IFNAR1

2.16e-05394231329638
Pubmed

Functional crosstalk between type I and II interferon through the regulated expression of STAT1.

STAT1 IFNAR1

2.16e-05394220436908
Pubmed

Stromal interferon-γ signaling and cross-presentation are required to eliminate antigen-loss variants of B cell lymphomas in mice.

STAT1 IFNAR1

2.16e-05394222479645
Pubmed

Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity.

STAT1 IFNAR1

2.16e-05394228753426
Pubmed

Critical roles for both STAT1-dependent and STAT1-independent pathways in the control of primary dengue virus infection in mice.

STAT1 IFNAR1

2.16e-05394216148142
Pubmed

Tyrosine kinase 2 controls IL-1ß production at the translational level.

STAT1 IFNAR1

2.16e-05394220713887
Pubmed

H3K27 acetylation activated-COL6A1 promotes osteosarcoma lung metastasis by repressing STAT1 and activating pulmonary cancer-associated fibroblasts.

SOCS5 STAT1

2.16e-05394233391546
Pubmed

Bioluminescent imaging reveals divergent viral pathogenesis in two strains of Stat1-deficient mice, and in αßγ interferon receptor-deficient mice.

STAT1 IFNAR1

2.16e-05394221915277
Pubmed

Neuropeptide signaling activates dendritic cell-mediated type 1 immune responses through neurokinin-2 receptor.

STAT1 IFNAR1

2.16e-05394222474018
Pubmed

Induction of indoleamine 2,3-dioxygenase by uropathogenic bacteria attenuates innate responses to epithelial infection.

IDO1 IFNAR1

2.16e-05394222474038
Pubmed

Injury-induced type I IFN signaling regulates inflammatory responses in the central nervous system.

STAT1 IFNAR1

2.16e-05394220562259
Pubmed

Conditional Stat1 ablation reveals the importance of interferon signaling for immunity to Listeria monocytogenes infection.

STAT1 IFNAR1

2.16e-05394222719255
Pubmed

Viruses evade the immune system through type I interferon-mediated STAT2-dependent, but STAT1-independent, signaling.

STAT1 IFNAR1

2.16e-05394215723812
Pubmed

Distinct requirements for IFNs and STAT1 in NK cell function.

STAT1 IFNAR1

2.16e-05394211034357
Pubmed

Induction of IFN-alphabeta enables Listeria monocytogenes to suppress macrophage activation by IFN-gamma.

STAT1 IFNAR1

2.16e-05394220123961
Pubmed

Antiviral Functions of Type I and Type III Interferons in the Olfactory Epithelium.

STAT1 IFNAR1

2.16e-05394238136633
Pubmed

A type I IFN-Flt3 ligand axis augments plasmacytoid dendritic cell development from common lymphoid progenitors.

STAT1 IFNAR1

2.16e-05394224145513
Pubmed

Alpha/beta interferons regulate murine gammaherpesvirus latent gene expression and reactivation from latency.

STAT1 IFNAR1

2.16e-05394216254350
Pubmed

IDO1 and TGF-β Mediate Protective Effects of IFN-α in Antigen-Induced Arthritis.

IDO1 IFNAR1

2.16e-05394227647832
Pubmed

IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses.

STAT1 IFNAR1

2.16e-05394217227866
Pubmed

Type I interferons regulate cytolytic activity of memory CD8(+) T cells in the lung airways during respiratory virus challenge.

STAT1 IFNAR1

2.16e-05394220637658
Pubmed

Ferroptosis triggered by STAT1- IRF1-ACSL4 pathway was involved in radiation-induced intestinal injury.

ACSL4 STAT1

2.16e-05394237611494
Pubmed

Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment.

STAT1 IFNAR1

2.16e-05394232643603
Pubmed

Immune response in Stat2 knockout mice.

STAT1 IFNAR1

2.16e-05394211163195
Pubmed

Role for innate IFNs in determining respiratory syncytial virus immunopathology.

STAT1 IFNAR1

2.16e-05394215905569
Pubmed

The virion host shutoff protein of herpes simplex virus 1 blocks the replication-independent activation of NF-κB in dendritic cells in the absence of type I interferon signaling.

STAT1 IFNAR1

2.16e-05394221937652
Pubmed

The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response.

STAT1 IFNAR1

2.16e-05394223273843
Pubmed

Obstructive Lymphangitis Precedes Colitis in Murine Norovirus-Infected Stat1-Deficient Mice.

STAT1 IFNAR1

2.16e-05394229753791
Pubmed

Induction and role of indoleamine 2,3 dioxygenase in mouse models of influenza a virus infection.

IDO1 IFNAR1

2.16e-05394223785507
Pubmed

Type I interferon limits mast cell-mediated anaphylaxis by controlling secretory granule homeostasis.

STAT1 IFNAR1

2.16e-05394231730616
Pubmed

Palmitoylation of interferon-alpha (IFN-alpha) receptor subunit IFNAR1 is required for the activation of Stat1 and Stat2 by IFN-alpha.

STAT1 IFNAR1

2.16e-05394219561067
Pubmed

Type I IFN modulates innate and specific antiviral immunity.

STAT1 IFNAR1

4.32e-05494210754318
Pubmed

Dendritic cells require STAT-1 phosphorylated at its transactivating domain for the induction of peptide-specific CTL.

STAT1 IFNAR1

4.32e-05494219620292
Pubmed

Stat2 loss leads to cytokine-independent, cell-mediated lethality in LPS-induced sepsis.

STAT1 IFNAR1

4.32e-05494223653476
Pubmed

Species-Specific Pathogenicity of Severe Fever with Thrombocytopenia Syndrome Virus Is Determined by Anti-STAT2 Activity of NSs.

STAT1 IFNAR1

4.32e-05494230814285
Pubmed

Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN-alpha/beta on antigen cross-presentation.

STAT1 IFNAR1

4.32e-05494217018853
Pubmed

Abnormal taste perception in mice lacking the type 3 inositol 1,4,5-trisphosphate receptor.

TRPM5 ITPR2

4.32e-05494217925404
Pubmed

A novel 16-kilodalton cellular protein physically interacts with and antagonizes the functional activity of c-myc promoter-binding protein 1.

TRAPPC2B TRAPPC2

4.32e-05494211134351
Pubmed

Stat1 and Stat2 but not Stat3 arbitrate contradictory growth signals elicited by alpha/beta interferon in T lymphocytes.

STAT1 IFNAR1

4.32e-05494215964802
Pubmed

STAT1 affects lymphocyte survival and proliferation partially independent of its role downstream of IFN-gamma.

STAT1 IFNAR1

4.32e-05494210640742
Pubmed

STAT2 mediates innate immunity to Dengue virus in the absence of STAT1 via the type I interferon receptor.

STAT1 IFNAR1

4.32e-05494221379341
Pubmed

IFN-alpha activates Stat6 and leads to the formation of Stat2:Stat6 complexes in B cells.

STAT1 IFNAR1

4.32e-05494210490982
Pubmed

STAT1 plays a critical role in the regulation of antimicrobial effector mechanisms, but not in the development of Th1-type responses during toxoplasmosis.

STAT1 IFNAR1

4.32e-05494214688355
Pubmed

A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies.

STAT1 IFNAR1

4.32e-05494232553273
Pubmed

A Y chromosome-linked factor impairs NK T development.

STAT1 IFNAR1

4.32e-05494217785781
Pubmed

Cutting edge: STAT1 and T-bet play distinct roles in determining outcome of visceral leishmaniasis caused by Leishmania donovani.

STAT1 IFNAR1

4.32e-05494216785492
Pubmed

Association of PD-L1 and IDO1 expression with JAK-STAT pathway activation in soft-tissue leiomyosarcoma.

IDO1 STAT1

4.32e-05494232951108
Pubmed

Replication of linkage on chromosome 7q22 and association of the regional Reelin gene with working memory in schizophrenia families.

RELN GRM3

4.32e-05494217684500
Pubmed

The role of IFN in respiratory syncytial virus pathogenesis.

STAT1 IFNAR1

4.32e-05494211884466
Pubmed

Visualizing the Selectivity and Dynamics of Interferon Signaling In Vivo.

STAT1 IFNAR1

4.32e-05494231825834
Pubmed

Murine Coronavirus Infection Activates the Aryl Hydrocarbon Receptor in an Indoleamine 2,3-Dioxygenase-Independent Manner, Contributing to Cytokine Modulation and Proviral TCDD-Inducible-PARP Expression.

IDO1 IFNAR1

4.32e-05494231694960
Pubmed

SARS-CoV pathogenesis is regulated by a STAT1 dependent but a type I, II and III interferon receptor independent mechanism.

STAT1 IFNAR1

4.32e-05494220386712
Pubmed

Lack of the IFN-γ signal leads to lethal Orientia tsutsugamushi infection in mice with skin eschar lesions.

STAT1 IFNAR1

4.32e-05494238743761
Pubmed

Herpes Simplex Virus and Interferon Signaling Induce Novel Autophagic Clusters in Sensory Neurons.

STAT1 IFNAR1

4.32e-05494226912623
Pubmed

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells.

IDO1 IFNAR1

4.32e-05494221804557
Pubmed

IL-27 induces an IFN-like signature in murine macrophages which in turn modulate colonic epithelium.

STAT1 IFNAR1

4.32e-05494237153622
Pubmed

Human protein phosphatase PP6 regulatory subunits provide Sit4-dependent and rapamycin-sensitive sap function in Saccharomyces cerevisiae.

PPP6R2 PPP6R3

4.32e-05494219621075
Pubmed

Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling.

STAT1 IFNAR1

4.32e-0549429121453
Pubmed

The WD motif-containing protein receptor for activated protein kinase C (RACK1) is required for recruitment and activation of signal transducer and activator of transcription 1 through the type I interferon receptor.

STAT1 IFNAR1

4.32e-05494211301323
Pubmed

T cell-intrinsic and -extrinsic contributions of the IFNAR/STAT1-axis to thymocyte survival.

STAT1 IFNAR1

4.32e-05494221949815
Pubmed

Blockade of interferon signaling decreases gut barrier integrity and promotes severe West Nile virus disease.

STAT1 IFNAR1

4.32e-05494237749080
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

DLGAP2 MACF1 CNKSR2 PLCL1 GRM3 DYNC1H1

6.38e-0525194627507650
Pubmed

Myeloid Cells Restrict MCMV and Drive Stress-Induced Extramedullary Hematopoiesis through STAT1.

STAT1 IFNAR1

7.19e-05594230811989
Pubmed

STAT1 modulates tissue wasting or overgrowth downstream from PDGFRβ.

STAT1 IFNAR1

7.19e-05594228924035
Pubmed

Distinct Roles of Type I and Type III Interferons in Intestinal Immunity to Homologous and Heterologous Rotavirus Infections.

STAT1 IFNAR1

7.19e-05594227128797
Pubmed

Novel functions of tyrosine kinase 2 in the antiviral defense against murine cytomegalovirus.

STAT1 IFNAR1

7.19e-05594216148148
Pubmed

High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells.

STAT1 IFNAR1

7.19e-05594217846149
Pubmed

Inactivation of Protein Tyrosine Phosphatases Enhances Interferon Signaling in Pancreatic Islets.

STAT1 IFNAR1

7.19e-05594225732191
Pubmed

Multiple sclerosis and hepatitis C virus infection are associated with single nucleotide polymorphisms in interferon pathway genes.

STAT1 IFNAR1

7.19e-05594218338947
Pubmed

Type II but Not Type I IFN Signaling Is Indispensable for TLR7-Promoted Development of Autoreactive B Cells and Systemic Autoimmunity.

STAT1 IFNAR1

7.19e-05594231900342
Pubmed

Dysregulated IFN-γ signals promote autoimmunity in STAT1 gain-of-function syndrome.

STAT1 IFNAR1

7.19e-05594237406138
Pubmed

Dual metabotropic glutamate receptor signaling enables coordination of astrocyte and neuron activity in developing sensory domains.

GRM3 ITPR2

7.19e-05594234245686
Pubmed

Polymorphisms of candidate genes in Slovak autistic patients.

GABRG3 RELN

7.19e-05594220436377
Pubmed

Norovirus evolution in immunodeficient mice reveals potentiated pathogenicity via a single nucleotide change in the viral capsid.

STAT1 IFNAR1

7.19e-05594233705489
Pubmed

Bst2/Tetherin Is Induced in Neurons by Type I Interferon and Viral Infection but Is Dispensable for Protection against Neurotropic Viral Challenge.

STAT1 IFNAR1

7.19e-05594226311886
Pubmed

Interferon-β acts directly on T cells to prolong allograft survival by enhancing regulatory T cell induction through Foxp3 acetylation.

STAT1 IFNAR1

7.19e-05594235148827
Pubmed

IL-36 promotes anti-viral immunity by boosting sensitivity to IFN-α/β in IRF1 dependent and independent manners.

STAT1 IFNAR1

7.19e-05594231619669
CytobandXp22.12

CNKSR2 MAP3K15

1.15e-048942Xp22.12
GeneFamilyProtein phosphatase 6 regulatory subunits

PPP6R2 PPP6R3

1.89e-046652699
GeneFamilyEF-hand domain containing

VSNL1 DGKG MACF1 EFHB HPCAL4

1.14e-03219655863
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DGKG PLCL1 GRM3 CPED1 ANO3 HEPH

1.65e-06170946876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DGKG PLCL1 GRM3 CPED1 ANO3 HEPH

1.65e-061709461f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCellIIH-CD8-naive_CD4|IIH / Condition, Cell_class and T cell subcluster

NPC1 CARM1 ERCC6 SYTL2 INPP5F SLC35A5

1.82e-061739464f2843371d18af766c1892529ce286f56c956fde
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MSMO1 SYTL2 GPAT3 DGKG PLEKHA2 ANO3

2.01e-061769460710689e66deba179b0a8038cdd56b4834984f12
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRG3 DLGAP2 IDO1 CNKSR2 ANO3 HPCAL4

2.45e-06182946d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRG3 DLGAP2 IDO1 CNKSR2 ANO3 HPCAL4

2.45e-061829466cde859edfe7607bd7ada89d20258413d06f4207
ToppCellCOVID-19-Heart-Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

SOCS5 SYTL2 KCNQ3 PLCL1 MUC3A ENPEP

2.60e-0618494621790cdfa3b4036ad413fd44b94e31563116f25f
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DLGAP2 VSNL1 IPCEF1 SYTL2 CNKSR2 ANO3

2.77e-06186946bdbe290f81106a53c8c30a92fbb385597c62b2ac
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DLGAP2 VSNL1 SYTL2 VPS13A CNKSR2 ANO3

3.04e-06189946a75226616340045b581d08429d2e123e041dee55
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DLGAP2 VSNL1 SYTL2 VPS13A CNKSR2 ANO3

3.13e-06190946d594da827e3c16644952b9589cc12b947ce36279
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DLGAP2 VSNL1 SYTL2 VPS13A CNKSR2 ANO3

3.13e-0619094649e09cdb843b3d889a06a811aa5affae68b25a75
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

VSNL1 SYTL2 DGKG PLCL1 CPED1 ADGRG6

3.33e-06192946992d08092edbc68c47b945deb8708379738c239a
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DLGAP2 VSNL1 SYTL2 VPS13A CNKSR2 ANO3

3.33e-061929465c7e8b80b44d9ce55c797cdf8267ac5382e26cac
ToppCellPCW_10-12|World / Celltypes from embryonic and fetal-stage human lung

GABRG3 FAP SP100 MACF1 CNKSR2 ADGRG6

3.86e-0619794647fd8b0d596c5db1a722473c8efbb17a6bbe7538
ToppCellCOVID-19_Mild|World / 5 Neutrophil clusters in COVID-19 patients

RELN VSNL1 GPAT3 DDX60L CPED1

1.78e-051529452ff0980dfd8d430cca14649151d856edef115720
ToppCellCOVID-19_Moderate-multiplets|World / disease group, cell group and cell class

ATP8A1 IDO1 SYTL2 MACF1 ADGRG6

2.01e-05156945afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCellGlobus_pallidus-Neuronal-Excitatory|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

DLGAP2 CNKSR2 MUC3A ANO3 HPCAL4

2.27e-05160945f843287ed57d2d5a3b3f6dfb03b6934e330e6645
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-4|TCGA-Lung / Sample_Type by Project: Shred V9

FAP SYTL2 KCNQ3 DDX60L IFNAR1

3.58e-051769450923b01137d6f9956ca815b41102c81e82624065
ToppCellCOVID-19-lung-MAST|COVID-19 / Disease (COVID-19 only), tissue and cell type

ACSL4 SYTL2 GPAT3 PLEKHA2 PLCL1

3.58e-05176945473c45a381ca109207d66ed1635668b391ea0e1f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GABRG3 FAP SOCS5 CPED1 HEPH

3.99e-05180945280ff5c8f292be1b88120db5ff1788b750644856
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GABRG3 FAP SOCS5 CPED1 HEPH

3.99e-05180945fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IPCEF1 SYTL2 VPS13A SIDT1 MACF1

4.20e-05182945e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IPCEF1 SYTL2 VPS13A SIDT1 MACF1

4.20e-051829451710eab3037a87609d21838be2d2d29c3bc36651
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

VSNL1 SYTL2 DGKG PLCL1 CPED1

4.32e-051839458a799807fbf24456a9811e0c64068187940a2f71
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYTL2 DGKG PLCL1 CPED1 ADGRG6

4.43e-05184945689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellFrontal_cortex-Neuronal-Excitatory|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

IPCEF1 CNKSR2 ANO3 HPCAL4 CFAP65

4.43e-051849456e17c8151d6dc543de16d804db956c63c3fda414
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SP100 SYTL2 SIDT1 MACF1 PLEKHA2

4.43e-05184945b12fb85a064f715a4f0ada1df8e422c359b573cf
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CARM1 ERCC6 PLEKHA2 EFHB CFAP65

4.54e-0518594505bc89a566b0db90ae06506e067190a4739a0974
ToppCellfacs-Marrow-T-cells-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SP100 SYTL2 SIDT1 MACF1 PLEKHA2

4.54e-05185945e1fd0a807def8c2127194108b1a30c6de7024292
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DLGAP2 SYTL2 VPS13A CNKSR2 ANO3

4.66e-0518694584ba666237c18189d7e7556bd92dd953af733c00
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DLGAP2 VSNL1 SYTL2 CNKSR2 ANO3

4.78e-05187945f18628ffc7ff7c762b8339ba8822cf0c3157f469
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DGKG PLCL1 GRM3 CPED1 ANO3

4.78e-0518794515d6e158562d7d85af3ceaf955439b379c8fce81
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DGKG PLCL1 GRM3 CPED1 ANO3

4.78e-05187945f62074b631fd45ad299c69d71b09267b04d656ee
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DLGAP2 VSNL1 SYTL2 CNKSR2 ANO3

4.91e-0518894550c1b1d690f0e9443082f2adf4f1b8e9ce4cd337
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DGKG PLCL1 GRM3 CPED1 ANO3

4.91e-0518894532f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

EXOC6B GPAT3 DGKG PLCL1 CPED1

5.03e-051899450a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DLGAP2 VSNL1 SYTL2 CNKSR2 ANO3

5.03e-05189945c3df0e3c50af8f1cfb4d790e668bd7f42b276992
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

EXOC6B GPAT3 DDX60L PLCL1 CPED1

5.16e-0519094593c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellPCW_13-14|World / Celltypes from embryonic and fetal-stage human lung

SP100 MACF1 PLEKHA2 CNKSR2 ADGRG6

5.16e-0519094562a3ec1ae0829602b0569cc051210551644f1d46
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYTL2 DGKG PLCL1 CPED1 ADGRG6

5.29e-051919457853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACSL4 ATP8A1 CST8 ENPEP LRG1

5.42e-051929457ccdb977320d09f21e70e7718ead73eeb56d0c48
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

VSNL1 CPED1 ANO3 HEPH ADGRG6

5.42e-0519294572881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACSL4 ATP8A1 CST8 ENPEP LRG1

5.42e-05192945f206c015f091234e2c86dfa66926e97b2ea99690
ToppCellPND28-Epithelial-Epithelial_Alveolar|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACSL4 ATP8A1 CST8 ENPEP LRG1

5.42e-0519294569963e8dc6d6368243e61da133484eb23225625a
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACSL4 ATP8A1 CST8 ENPEP LRG1

5.42e-05192945bfc68af68fdb99ddfe4add49671e4b4c26e6f962
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAP SP100 MYOC GPAT3 ELOVL6

5.56e-051939457cd9671e0ac64f7f3607f564485c63abbb7e7a63
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DOCK5 GABRG3 FAP MACF1 ADGRG6

5.69e-05194945b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-innate_lymphocytic|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DOCK5 IPCEF1 ABCB5 SYTL2 ELOVL6

5.83e-0519594563e132fd6e4318299dd47bbe8ed3bf120efe46dd
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DOCK5 GABRG3 FAP MACF1 ADGRG6

5.83e-051959450e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN KIF1B VPS13A MACF1 DYNC1H1

5.83e-051959453e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN KIF1B VPS13A MACF1 DYNC1H1

5.83e-051959457796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellParenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

VSNL1 DGKG PLEKHA2 CPED1 ADGRG6

6.12e-05197945f66945f9007d59d4208849c7fd727f8519713fbc
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DOCK5 ATP8A1 PLCL1 INPP5F GRM3

6.12e-0519794582b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG3 DLGAP2 VSNL1 KCNQ3 CNKSR2

6.27e-051989458ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG3 DLGAP2 VSNL1 KCNQ3 CNKSR2

6.27e-051989454ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NPC1 SP100 SYTL2 VPS13A MACF1

6.42e-05199945f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellmild-MAIT|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SP100 ZNF652 SYTL2 MACF1 ELOVL6

6.42e-05199945cbe1fb6d2c5fca7a1baf1ad20afcdf8e8e11bd84
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GABRG3 DLGAP2 RELN VSNL1 HPCAL4

6.58e-052009452f481e2fd248c02a5aa2e0248c16808df142fed2
ToppCellmild-CD8+_Tem|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NPC1 SP100 ATP8A1 SYTL2 MACF1

6.58e-05200945d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

VSNL1 SYTL2 DGKG CNKSR2 ADGRG6

6.58e-052009450c648941447c738caf62f2d71e296d6cca492c8b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GABRG3 DLGAP2 RELN VSNL1 HPCAL4

6.58e-05200945bd4b9f6b37f4a3c960c4149cf0cfd2caf3327d2d
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

VSNL1 SYTL2 DGKG CPED1 ADGRG6

6.58e-05200945f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

GABRG3 DLGAP2 VSNL1 KCNQ3 CNKSR2

6.58e-0520094548d801219bc771d6c7e151dc88ca4c179988de85
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SP100 IDO1 DDX60L DYNC1H1 STAT1

6.58e-0520094589821a264e872ed53e08e9d3609d5cc5c314503e
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

DOCK5 VSNL1 SYTL2 CPED1 ADGRG6

6.58e-05200945a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

VSNL1 SYTL2 DGKG CNKSR2 ADGRG6

6.58e-05200945522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SP100 MACF1 DDX60L DYNC1H1 STAT1

6.58e-0520094512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD4+_T_activated|COVID-19_Mild / Disease, condition lineage and cell class

SP100 IPCEF1 PLCL1 HPCAL4 STAT1

6.58e-05200945d9e8a0d047d4403fb7265fde7448e23a7780785c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GABRG3 DLGAP2 RELN VSNL1 HPCAL4

6.58e-05200945dc674124475edf83908b51a4e1454bc2dc4f06fa
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

VSNL1 SYTL2 DGKG CNKSR2 ADGRG6

6.58e-0520094594f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCellLPS_only-Mesenchymal_myocytic|LPS_only / Treatment groups by lineage, cell group, cell type

VSNL1 SYTL2 DGKG CPED1 ADGRG6

6.58e-052009458bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCellCOVID-19_Mild-Neu_1|World / 5 Neutrophil clusters in COVID-19 patients

RELN VSNL1 GPAT3 CPED1

1.43e-04125944e58c208b4355252ceabe04a468dd19a1f436182c
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Stem_cells-neuroepithelial-like_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

DOCK5 SYTL2 PLCL1 DCUN1D4

1.52e-041279449071cd0953c8bb6746dc9cd13d153e3d6ef40b08
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue-2|TCGA-Bladder / Sample_Type by Project: Shred V9

MYOC ABCB5 PLCL1 CPED1

2.26e-041419441baa054c2ae3b446d1954244b7fbf8af824ef345
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK5 DLGAP2 IDO1 IPCEF1

2.39e-041439444a0f26eef935fe68a1da5d319503059a8a8682dd
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK5 DLGAP2 IDO1 IPCEF1

2.39e-0414394465328a0a2f3972fac596e07933e74b2ef7cceb84
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Neuroendocrine_Carcinoma-2|TCGA-Pancreas / Sample_Type by Project: Shred V9

TCP11X1 TCP11X2 ADGRF3 CFAP65

2.59e-04146944bc2adef529d0bbfcccef7435401a47a6ffcc1832
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Neuroendocrine_Carcinoma|TCGA-Pancreas / Sample_Type by Project: Shred V9

TCP11X1 TCP11X2 ADGRF3 CFAP65

2.59e-0414694472c1e7e0c2b6ff6c4084af61fa19c2b8eab16eda
ToppCellCOVID-19_Moderate-multiplets|COVID-19_Moderate / disease group, cell group and cell class

IDO1 SYTL2 MACF1 ADGRG6

2.65e-04147944baf15c773d7751bc6f64d4974a22738626f2b3ff
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

GABRG3 DLGAP2 RELN ABCB5

2.72e-04148944d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GPAT3 ADGRF3 CPED1 ADGRG6

3.09e-0415394491e9d70a5d3f6fd68c284ed0cc113f03d7d1e10b
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GPAT3 ADGRF3 CPED1 ADGRG6

3.09e-04153944f17f62646633cf95c810dcd5328978058741b276
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-Klrb1a/b/c(-)_NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYZL4 SIDT1 CNKSR2 LRG1

3.09e-04153944cb144b8c487286384b47fdff88ff98fcf0508899
ToppCellTCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue-Thryoid_normal_tissue-3|TCGA-Thryoid / Sample_Type by Project: Shred V9

PLA2R1 RELN MYOC IPCEF1

3.17e-041549444e9203c220a44c70cd7979796a0b461991422257
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IDO1 GPAT3 ADGRF3 ADGRG6

3.17e-041549445967a0a33456d5930fc492a700ebb015ac050abb
ToppCell343B-Myeloid-Dendritic-cDC1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

IDO1 ZNF652 PLEKHA2 ADGRG6

3.17e-0415494471d33b5dbfab5820e3daddb01806a69116ba8008
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Cpa6|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IPCEF1 PLEKHA2 ANO3 HPCAL4

3.17e-0415494412cbc38bc1f7231c67e1d2d5e86e95bc12e24682
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP2 TRPM5 MSH3 CFAP65

3.25e-04155944441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 PLA2R1 TMC1 ENPEP

3.25e-04155944e7f49e2fdaf184fa6b4e685518004e7deff1316d
ToppCellprimary_visual_cortex-Non-neuronal-pericyte_cell-Peri-Peri_Kcnj8|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PLA2R1 CPED1 ENPEP ITPR2

3.25e-04155944ced64e26962c5c6e6d539f361fe57ab0b399e999
ToppCellprimary_visual_cortex-Non-neuronal-pericyte_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PLA2R1 CPED1 ENPEP ITPR2

3.25e-041559440f24ef6486aef354f0911c06932cb01d1a0525ac
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IDO1 GPAT3 ADGRF3 ADGRG6

3.25e-04155944fab281db4c275d51240b122be78713c839ba5a95
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK5 PLA2R1 TMC1 ENPEP

3.25e-041559445a872ca70ae8c30b57f45a6772d7bf565e0c2663
ToppCellprimary_visual_cortex-Non-neuronal-pericyte_cell-Peri|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PLA2R1 CPED1 ENPEP ITPR2

3.25e-04155944d8b5145258f075b15080f8739f537f48dd22225e
ToppCellTCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue-Thryoid_normal_tissue|TCGA-Thryoid / Sample_Type by Project: Shred V9

PLA2R1 RELN MYOC IPCEF1

3.49e-041589448e48952af0831a1fc71ad422e8216b5a92a75991
ToppCellTCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue|TCGA-Thryoid / Sample_Type by Project: Shred V9

PLA2R1 RELN MYOC IPCEF1

3.49e-04158944e5b55c15a8c99c8d7fc94949f0d3c22e0c3fee7b
ToppCellTCGA-Thryoid-Solid_Tissue_Normal|TCGA-Thryoid / Sample_Type by Project: Shred V9

PLA2R1 RELN MYOC IPCEF1

3.49e-0415894455214d674808584e4d48f8c5e3b8c0e206cb9bb8
ToppCellPosterior_cortex|World / BrainAtlas - Mouse McCarroll V32

DLGAP2 IPCEF1 VPS13A CNKSR2

3.58e-0415994418e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PLA2R1 TMC1 CNKSR2 HPCAL4

3.58e-04159944ae53ab7a1339007d0b245c6c291ac61e5ff5b682
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PLA2R1 TMC1 CNKSR2 HPCAL4

3.58e-04159944b05fda31b77536a1878f55d3199563b53f9420b2
DiseaseX-linked spondyloepiphyseal dysplasia tarda (implicated_via_orthology)

TRAPPC2B TRAPPC2

9.83e-062932DOID:0080362 (implicated_via_orthology)
Diseaseperipheral arterial disease, traffic air pollution measurement

DLGAP2 CST8 MACF1 GRM3 ADGRG6 ITPR2

3.54e-05194936EFO_0004265, EFO_0007908
Diseasechildhood trauma measurement, alcohol consumption measurement

GABRG3 DLGAP2 PLA2R1 CNKSR2

7.64e-0571934EFO_0007878, EFO_0007979
Diseaseblood manganese measurement

GABRG3 INPP5F ADCY9

8.39e-0527933EFO_0007581
Diseasespondyloepiphyseal dysplasia congenita (implicated_via_orthology)

TRAPPC2B TRAPPC2

1.46e-046932DOID:14789 (implicated_via_orthology)
Diseasepallidum volume change measurement

EFHB ADCY9

7.49e-0413932EFO_0021494
Diseasegrip strength measurement

KIF1B PLCL1 INPP5F EFHB GRM3 ADCY9

8.55e-04350936EFO_0006941
Diseasebody surface area

DOCK5 DGKG MACF1 DCUN1D4 CPED1 ADCY9 PPP6R3 ADGRG6

9.76e-04643938EFO_0022196
DiseasePolyposis, Adenomatous Intestinal

MSH3 LRG1

1.15e-0316932C2713442
DiseaseFamilial Intestinal Polyposis

MSH3 LRG1

1.15e-0316932C2713443
DiseaseAdenomatous Polyposis Coli

MSH3 LRG1

1.30e-0317932C0032580
DiseaseCharcot-Marie-Tooth disease type 2

KIF1B DYNC1H1

1.30e-0317932cv:C0270914
Diseaseresponse to methotrexate, neurotoxicity

MACF1 PLCL1

1.62e-0319932EFO_0011057, GO_0031427
Diseaseglaucoma (is_marker_for)

APOA4 HEPH

1.80e-0320932DOID:1686 (is_marker_for)
DiseaseHematochezia, response to radiation

GABRG3 DLGAP2

1.80e-0320932GO_0009314, HP_0002573
Diseasesex interaction measurement, cerebral amyloid angiopathy

EFHB ADCY9

1.98e-0321932EFO_0006790, EFO_0008343
DiseaseArthrogryposis

ERCC6 DYNC1H1

1.98e-0321932C0003886
Diseasebone density, lean body mass

CPED1 PPP6R3

1.98e-0321932EFO_0003923, EFO_0004995
Diseasephosphatidylcholine measurement

DLGAP2 SOCS5 MACF1 APOA4 DYNC1H1

2.08e-03284935EFO_0010226
Diseasecolorectal carcinoma (is_implicated_in)

ERCC6 MSH3

2.18e-0322932DOID:0080199 (is_implicated_in)
Diseasedigestive system infectious disorder

NPC1 ITPR2

3.04e-0326932MONDO_0043424
Diseasemethionine measurement

FMO4 PLCL1

3.04e-0326932EFO_0009771

Protein segments in the cluster

PeptideGeneStartEntry
AEWMIAAQTCFKYNF

ACSL4

161

O60488
WKLDAQNMGYFTLQE

DCUN1D4

146

Q92564
MSCFEAQGFKWNLYE

ADGRF3

311

Q8IZF5
YRWLQAQKDKMFSQN

LRG1

311

P02750
RTYKWSFQLNELDNM

ARID4A

1166

P29374
QYWSLLNVFEQFQFM

CPED1

501

A4D0V7
DNKNLCVQMFDWFDY

CLK2

221

P49760
LAFKAMLYQDIAWFD

ABCB5

771

Q2M3G0
DIYNFRLWNFTMNAK

ADGRG6

306

Q86SQ4
YQAKAMAEILRFFNW

GRM3

196

Q14832
MWDKSCDYLFFRNNM

CFAP418

146

Q96NL8
SAQLLMSQKFQQFYW

DLGAP2

911

Q9P1A6
EAFWENKQMENNFYK

ERCC6

1166

Q03468
VKFTQAYFINWDLDM

ATP8A1

366

Q9Y2Q0
MEQFASFKWNFIKQY

ANO3

576

Q9BYT9
QFYLNQLLEFMHIWK

PIK3C2G

386

O75747
FFQQTEDLYNEMKWQ

ITPR2

2196

Q14571
MWDYFSQLSNNAKEA

APOA4

31

P06727
PNWMANLSYIKNFRF

ANKRD27

326

Q96NW4
EPFKNAWNYMLNNYT

MSMO1

31

Q15800
AWNYMLNNYTKFQIA

MSMO1

36

Q15800
YFAKLWTMHNAQDLQ

MSH3

1106

P20585
NLPDFYNDWMFIAKH

IDO1

31

P14902
SFEQKLNWAFEMYDL

HPCAL4

96

Q9UM19
NWVCLAYFESKFNPM

LYZL4

46

Q96KX0
ALNDKDMNDWLYAFN

KIF1B

1781

O60333
YFRQFWNEQSTKFMD

CFAP65

1706

Q6ZU64
ECWQNMYKLLNFYSL

KIAA1109

2701

Q2LD37
FRMKAYAFWQSSEDA

KCNQ3

476

O43525
KMNKWCEYFILSNLN

DDX60L

331

Q5H9U9
QLYMEQFTKANFWYQ

CARM1

301

Q86X55
FSFDYQKTGMDNWIK

IFNAR1

61

P17181
CWNEKQAFMFTEQYK

KIAA1586

136

Q9HCI6
YRDFNKTFWNQMQKI

MUC3A

3046

Q02505
FMNHEKFWDYLQEFA

FMO4

81

P31512
LFAWDNLNMVTYDIK

MYOC

486

Q99972
AAVQYQDTLQAMFDW

MACF1

2241

O94854
TELQLWQMESFFAKY

ENPEP

901

Q07075
QKIDQFLQLADYDWM

EXOC6B

616

Q9Y2D4
FYQKYSDMQWAIDNF

RELN

2836

P78509
QNFDMTYSVQFGDLW

NSUN4

46

Q96CB9
ATNWIEYMFNKDNGQ

NPC1

186

O15118
NLPMSYWLNNYVFKN

PORCN

306

Q9H237
FNSRMKNKLWYFEFG

DGKG

606

P49619
NVYAKNNMWFDFGFD

GAL3ST2

186

Q9H3Q3
MQENWKKSFLFSALY

ELOVL6

26

Q9H5J4
WYSNQMAEKADGFVN

IPCEF1

76

Q8WWN9
FFMDQASFELQLWNN

DOCK5

1031

Q9H7D0
DLSFMYRWFKNCNLV

SDR9C7

6

Q8NEX9
SYLWTDNLQEFMKNF

DNAH17

991

Q9UFH2
ADQKSWRLYQFDFMG

GABRG3

211

Q99928
QFGDAFWNSSKYNMV

GPAT3

336

Q53EU6
ESQWQMEQEFFKGYL

CEP250

156

Q9BV73
DFNNNMLWFNFKLRV

ADCY9

1151

O60503
AMTNFDVTYNWIQDK

ERP44

226

Q9BS26
MGSDFQYENANMWFK

MAN2B1

316

O00754
QYENANMWFKNLDKL

MAN2B1

321

O00754
FINYLEFANFLNWKD

EFHB

616

Q8N7U6
DNAKSFEWLSQMRFY

DYNC1H1

1831

Q14204
KQCLWFAMQEYNKES

CST8

46

O60676
MFLQSYNNDQWTLIF

CTNS

316

O60931
TFWNLFEAILQFQMN

DHDDS

236

Q86SQ9
DDRFFWNKYMIQDLT

INPP5F

206

Q9Y2H2
MDLLLDLFFKYTWNN

PPP6R2

371

O75170
EKMNNYWDVGQFFSV

MAP3K15

441

Q6ZN16
FNIYLQAKNGWKTFM

RNF139

506

Q8WU17
YFLQANDQKDMKDWV

PLEKHA2

91

Q9HB19
KDDQQLKNMSGQWFY

SYTL2

41

Q9HCH5
YLSNMFDINSLWNNL

TAS2R39

281

P59534
QVANGIFFMLWNNKY

TAS2R42

251

Q7RTR8
MSQWYELQQLDSKFL

STAT1

1

P42224
KMWNNFKYRCQNLFG

SOCS5

6

O75159
MYNAFWNHLKEQLLS

TCP11X1

86

B4DZS4
MYNAFWNHLKEQLLS

TCP11X2

1

Q5H9J9
WYSNANQAAAMLDFR

HEPH

591

Q9BQS7
WYMNSDPNINQFFKY

MT-ND5

106

P03915
MKDSYFWIALQDQND

PLA2R1

571

Q13018
LWEANMIKAYNASFS

TMC1

481

Q8TDI8
FQQWKQMYLDLFLDI

CNKSR2

986

Q8WXI2
ALVNAQVDFQAMWYS

FAP

716

Q12884
QYRDFELSMKSQNYW

PLCL1

596

Q15111
NLFAYWNVKSQMFYL

VPS13A

211

Q96RL7
WNVKSQMFYLSDYDN

VPS13A

216

Q96RL7
SFEQKLNWAFNMYDL

VSNL1

96

P62760
QGNADMFWKFQRYNL

TRPM5

986

Q9NZQ8
QGQIFEAYNMAALWK

PDHA1

201

P08559
RNLKYASWKEFSDFM

SLC35A5

81

Q9BS91
AVMWAAALYFFFQNL

SIDT1

751

Q9NXL6
MWNNTAAADKQFYEK

SP100

806

P23497
RIWALKNAFDYFNNM

WDR44

536

Q5JSH3
SNNMYLKTVDKFNEW

TRAPPC2

56

P0DI81
FNMKKWDQFYSEVLG

UGT2B10

226

P36537
FKRFNSGTYNNQWMI

PLBD2

366

Q8NHP8
QWCGKDFNMKQYFDE

ZNF652

416

Q9Y2D9
SNNMYLKTVDKFNEW

TRAPPC2B

56

P0DI82
LNMFFKYTWNNFLHT

PPP6R3

376

Q5H9R7
MFDVSSFNQTQAWKY

TM4SF19

126

Q96DZ7
YVFDWNMLKFGAARN

CSNK1E

286

P49674
YKNIDKNSFNIMGDW

N4BP2

871

Q86UW6