Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP hydrolysis activity	DHX36 ABCA13 ABCA7 MDN1 ATP2C2 CHD6 DNAH6 HSPA9 DYNC1H1 KIFC1 DNAH10 ATP13A5 DDX51 FIGN ATP10A ATP2A3 SNRNP200	2.92e-05	441	242	17	GO:0016887
GeneOntologyBiologicalProcess	cell-cell adhesion	MAG CDHR2 GIMAP5 MBP ADGRV1 ITGA5 KIRREL2 NPHP4 PLXNB2 ITGB4 SVEP1 MAGI2 FAT2 PIK3CA SDK1 AMIGO2 FAT4 CARMIL2 PCDHGC5 UFL1 SLC4A1 CELSR2 MTOR TLN1 PCDHGB4 B4GALNT2 SOCS1 SCRIB HAS2 CDH10	7.33e-06	1077	238	30	GO:0098609
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	MAG CDHR2 MBP ITGA5 PLXNB2 MAGI2 FAT2 SDK1 AMIGO2 FAT4 PCDHGC5 CELSR2 PCDHGB4 CDH10	1.78e-05	313	238	14	GO:0098742
GeneOntologyCellularComponent	cell-cell junction	SIPA1L3 OBSCN ITGA5 KIRREL2 MFRP NPHP4 ADAM10 MAGI2 FAT2 AJAP1 PIK3CA CARMIL2 FRMPD2 PARD3B SLC4A1 SLC8A1 TLN1 SCRIB CDH10	7.08e-05	591	244	19	GO:0005911
HumanPheno	Hyperintensity of cerebral white matter on MRI	B4GALNT1 PIK3CA STRADA PYCR2 DPYD WARS1 MSTO1 MTOR SLC39A14	8.27e-06	74	96	9	HP:0030890
Domain	Calx_beta	ADGRV1 ITGB4 FRAS1 SLC8A1	1.73e-06	8	238	4	SM00237
Domain	Calx_beta	ADGRV1 ITGB4 FRAS1 SLC8A1	3.08e-06	9	238	4	IPR003644
Domain	Calx-beta	ADGRV1 ITGB4 FRAS1 SLC8A1	3.08e-06	9	238	4	PF03160
Domain	LamG	CNTNAP3B FAT2 FAT4 COL15A1 CELSR2 CSPG4	1.89e-05	44	238	6	SM00282
Domain	ATPase_dyneun-rel_AAA	MDN1 DNAH6 DYNC1H1 DNAH10	2.33e-05	14	238	4	IPR011704
Domain	AAA_5	MDN1 DNAH6 DYNC1H1 DNAH10	2.33e-05	14	238	4	PF07728
Domain	ConA-like_dom	CNTNAP3B ADGRV1 ITGB4 SVEP1 FAT2 SPSB3 FAT4 COL15A1 LMAN1 CELSR2 CSPG4 ADGRD2	2.55e-05	219	238	12	IPR013320
Domain	Laminin_G	CNTNAP3B FAT2 FAT4 COL15A1 CELSR2 CSPG4	9.35e-05	58	238	6	IPR001791
Domain	LAM_G_DOMAIN	CNTNAP3B FAT2 FAT4 CELSR2 CSPG4	1.15e-04	38	238	5	PS50025
Domain	Laminin_G_2	CNTNAP3B FAT2 FAT4 CELSR2 CSPG4	1.47e-04	40	238	5	PF02210
Domain	GM2_synthase	B4GALNT1 B4GALNT2	1.62e-04	2	238	2	IPR011143
Domain	SIM_C	SIM1 SIM2	1.62e-04	2	238	2	PS51302
Domain	SIM_C	SIM1 SIM2	1.62e-04	2	238	2	IPR010578
Domain	eRF1_2	ETF1 PELO	1.62e-04	2	238	2	PF03464
Domain	eRF1_1	ETF1 PELO	1.62e-04	2	238	2	PF03463
Domain	eRF1_3	ETF1 PELO	1.62e-04	2	238	2	PF03465
Domain	eRF1_2	ETF1 PELO	1.62e-04	2	238	2	IPR005141
Domain	eRF1_3	ETF1 PELO	1.62e-04	2	238	2	IPR005142
Domain	eRF1_1_Pelota	ETF1 PELO	1.62e-04	2	238	2	IPR005140
Domain	SIM_C	SIM1 SIM2	1.62e-04	2	238	2	PF06621
Domain	eRF1_1	ETF1 PELO	1.62e-04	2	238	2	SM01194
Domain	-	ADGRV1 SVEP1 FAT2 FAT4 LMAN1 CELSR2 CSPG4	2.13e-04	95	238	7	2.60.120.200
Domain	-	ITGB4 SVEP1 MDN1 ITIH6 SEC23A COL6A3	3.61e-04	74	238	6	3.40.50.410
Domain	Thr-tRNA-ligase_IIa	TARS1 TARS3	4.81e-04	3	238	2	IPR002320
Domain	ThrRS_core	TARS1 TARS3	4.81e-04	3	238	2	IPR033728
Domain	Cadherin_CS	CDHR2 FAT2 FAT4 PCDHGC5 CELSR2 PCDHGB4 CDH10	4.94e-04	109	238	7	IPR020894
Domain	HAD-like_dom	HDHD3 PSPH ATP2C2 ATP13A5 ATP10A ATP2A3	5.14e-04	79	238	6	IPR023214
Domain	AAA+_ATPase	ABCA13 ABCA7 MDN1 DNAH6 DYNC1H1 DNAH10 FIGN SNRNP200	5.26e-04	144	238	8	IPR003593
Domain	AAA	ABCA13 ABCA7 MDN1 DNAH6 DYNC1H1 DNAH10 FIGN SNRNP200	5.26e-04	144	238	8	SM00382
Domain	Glycos_transf_2	B4GALNT1 B3GNTL1 B4GALNT2 HAS2	5.43e-04	30	238	4	PF00535
Domain	Glyco_trans_2-like	B4GALNT1 B3GNTL1 B4GALNT2 HAS2	5.43e-04	30	238	4	IPR001173
Domain	CADHERIN_1	CDHR2 FAT2 FAT4 PCDHGC5 CELSR2 PCDHGB4 CDH10	6.14e-04	113	238	7	PS00232
Domain	Cadherin	CDHR2 FAT2 FAT4 PCDHGC5 CELSR2 PCDHGB4 CDH10	6.14e-04	113	238	7	PF00028
Domain	-	CDHR2 FAT2 FAT4 PCDHGC5 CELSR2 PCDHGB4 CDH10	6.47e-04	114	238	7	2.60.40.60
Domain	CADHERIN_2	CDHR2 FAT2 FAT4 PCDHGC5 CELSR2 PCDHGB4 CDH10	6.47e-04	114	238	7	PS50268
Domain	MT	DNAH6 DYNC1H1 DNAH10	6.70e-04	14	238	3	PF12777
Domain	AAA_8	DNAH6 DYNC1H1 DNAH10	6.70e-04	14	238	3	PF12780
Domain	Dynein_heavy_chain_D4_dom	DNAH6 DYNC1H1 DNAH10	6.70e-04	14	238	3	IPR024317
Domain	Dynein_HC_stalk	DNAH6 DYNC1H1 DNAH10	6.70e-04	14	238	3	IPR024743
Domain	Dynein_heavy_dom-2	DNAH6 DYNC1H1 DNAH10	6.70e-04	14	238	3	IPR013602
Domain	DHC_N2	DNAH6 DYNC1H1 DNAH10	6.70e-04	14	238	3	PF08393
Domain	CA	CDHR2 FAT2 FAT4 PCDHGC5 CELSR2 PCDHGB4 CDH10	6.82e-04	115	238	7	SM00112
Domain	Cadherin-like	CDHR2 FAT2 FAT4 PCDHGC5 CELSR2 PCDHGB4 CDH10	7.18e-04	116	238	7	IPR015919
Domain	Cadherin	CDHR2 FAT2 FAT4 PCDHGC5 CELSR2 PCDHGB4 CDH10	7.94e-04	118	238	7	IPR002126
Domain	DHC_fam	DNAH6 DYNC1H1 DNAH10	8.30e-04	15	238	3	IPR026983
Domain	Dynein_heavy	DNAH6 DYNC1H1 DNAH10	8.30e-04	15	238	3	PF03028
Domain	PI3/4_kinase_CS	SMG1 PIK3CA MTOR	8.30e-04	15	238	3	IPR018936
Domain	Dynein_heavy_dom	DNAH6 DYNC1H1 DNAH10	8.30e-04	15	238	3	IPR004273
Domain	Peroxin/Ferlin	FER1L5 TECPR1	9.54e-04	4	238	2	IPR006614
Domain	DysFC	FER1L5 TECPR1	9.54e-04	4	238	2	SM00694
Domain	DysFN	FER1L5 TECPR1	9.54e-04	4	238	2	SM00693
Domain	ATPase_P-typ_cyto_domN	ATP2C2 ATP13A5 ATP10A ATP2A3	9.87e-04	35	238	4	IPR023299
Domain	PI3Kc	SMG1 PIK3CA MTOR	1.01e-03	16	238	3	SM00146
Domain	-	SMG1 PIK3CA MTOR	1.01e-03	16	238	3	1.10.1070.11
Domain	ATPase_P-typ_P_site	ATP2C2 ATP13A5 ATP10A ATP2A3	1.10e-03	36	238	4	IPR018303
Domain	P_typ_ATPase	ATP2C2 ATP13A5 ATP10A ATP2A3	1.10e-03	36	238	4	IPR001757
Domain	ATPASE_E1_E2	ATP2C2 ATP13A5 ATP10A ATP2A3	1.10e-03	36	238	4	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP2C2 ATP13A5 ATP10A ATP2A3	1.22e-03	37	238	4	IPR008250
Domain	E1-E2_ATPase	ATP2C2 ATP13A5 ATP10A ATP2A3	1.22e-03	37	238	4	PF00122
Domain	P-loop_NTPase	DHX36 ABCA13 GIMAP5 NDST4 ABCA7 EHD2 EFTUD2 MAGI2 MDN1 AK5 HS3ST6 CHD6 DNAH6 DYNC1H1 KIFC1 RALB DNAH10 DDX51 LRRK1 FIGN SEPTIN11 SNRNP200	1.28e-03	848	238	22	IPR027417
Domain	-	DHX36 ABCA13 GIMAP5 NDST4 ABCA7 EHD2 EFTUD2 MDN1 AK5 HS3ST6 CHD6 DNAH6 DYNC1H1 RALB DNAH10 DDX51 LRRK1 FIGN SEPTIN11 SNRNP200	1.45e-03	746	238	20	3.40.50.300
Domain	Cation_ATPase_N	ATP2C2 ATP13A5 ATP2A3	1.45e-03	18	238	3	PF00690
Domain	PI3/4_kinase_cat_dom	SMG1 PIK3CA MTOR	1.45e-03	18	238	3	IPR000403
Domain	Cation_ATPase_N	ATP2C2 ATP13A5 ATP2A3	1.45e-03	18	238	3	SM00831
Domain	PI3_PI4_kinase	SMG1 PIK3CA MTOR	1.45e-03	18	238	3	PF00454
Domain	PI3_4_KINASE_1	SMG1 PIK3CA MTOR	1.45e-03	18	238	3	PS00915
Domain	PI3_4_KINASE_2	SMG1 PIK3CA MTOR	1.45e-03	18	238	3	PS00916
Domain	PI3_4_KINASE_3	SMG1 PIK3CA MTOR	1.45e-03	18	238	3	PS50290
Domain	FATC	SMG1 MTOR	1.58e-03	5	238	2	PF02260
Domain	VWF_A	ITGB4 SVEP1 MDN1 ITIH6 SEC23A COL6A3	1.68e-03	99	238	6	IPR002035
Domain	ATPase_P-typ_cation-transptr_N	ATP2C2 ATP13A5 ATP2A3	1.70e-03	19	238	3	IPR004014
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MYCBP2 INPPL1 SIPA1L3 OBSCN MED14 ITGA5 NPHP4 PLXNB2 BIRC6 ITGB4 ABCA7 MDN1 WDR90 GPC2 DYNC1H1 IGSF3 AGTRAP ANKRD13D FRAS1 RHBDF1 ICE1 LRRK1 REV3L MST1R SEPHS2 C2CD3 CELSR2 MTOR IL17RE NISCH TLN1 CSPG4 DUSP16 ATP2A3	6.12e-13	1105	245	34	35748872
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	DHX36 FAM234A B4GALNT1 ATP6V0A1 MYCBP2 SPOCK1 WDR25 ITGA5 PLXNB2 ADAM10 ITGB4 ABCA7 MELTF MOGS SVIL ZDHHC13 IGSF3 AMIGO2 FAT4 FRAS1 COL15A1 WARS1 TMEM248 LAMP1 DOLPP1 MST1R TXNDC15 LMAN1 CELSR2 CSPG4 SCRIB SLC39A14 ATP2A3 M6PR	6.05e-12	1201	245	34	35696571
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	ABCA13 MED14 CSMD3 ITGB4 EFTUD2 ACAN HNRNPA0 HSPA9 COL6A3 FAT4 FRAS1 PCDHGC5 APOB SEPHS2 SETBP1 ATP2A3 SNRNP200 CAPN15	3.11e-08	513	245	18	25798074
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	MAG DHX36 ATP6V0A1 SIPA1L3 ETF1 MBP FMNL2 MAGI2 SVIL HNRNPA0 PYCR2 DNAH6 HSPA9 TARS1 DYNC1H1 SEC23A ACSL6 CARMIL2 WARS1 SLC2A14 OGDH SLC4A1 TARS3 GUCY1A2 NISCH TLN1 SEPTIN11 ERC2 SCRIB SNRNP200	1.10e-07	1431	245	30	37142655
Pubmed	An ENU-mutagenesis screen in the mouse: identification of novel developmental gene functions.	PLXNB2 PTPRB SLC8A1 SCRIB	1.65e-07	8	245	4	21559415
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SMG1 NCALD SPOCK1 SIPA1L3 RFTN1 MDN1 HPCAL1 HNRNPA0 CHD6 PYCR2 ITIH6 DNAH6 HSPA9 AMIGO2 RALB PCDHGC5 GRIA4 REL CAT APOB OGDH SEPHS2 C2CD3 GUCY1A2 RDH11 CSPG4 PCDHGB4 ERC2 ATP2A3	4.30e-07	1442	245	29	35575683
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	SMG1 MYCBP2 SIPA1L3 ADGRV1 BIRC6 CHD6 TLN1 SETBP1 ERC2 SCRIB SNRNP200	6.59e-07	225	245	11	12168954
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	MAG MBP FMNL2 EHD2 PIK3CA ZDHHC13 IGSF3 AMIGO2 RALB CARMIL2 RHBDF1 APOB CELSR2 MTOR CSPG4 SCRIB SLC39A14	7.21e-07	569	245	17	30639242
Pubmed	Quantitative proteomics identifies a Dab2/integrin module regulating cell migration.	FAM234A ITGA5 PLXNB2 IGSF3 MST1R CSPG4	7.44e-07	45	245	6	19581412
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	DHX36 ITGA5 BIRC6 MDN1 HSPA9 DYNC1H1 SEC23A TECPR1 CAT OGDH TLN1 SEPTIN11 SNRNP200	1.18e-06	344	245	13	30333137
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	BCORL1 OBSCN FMNL2 BIRC6 TMEM260 MDN1 MOGS CHD6 DYNC1H1 FAT4 ICE1 REV3L TLN1 DUSP16 CCDC87 CHRD SCRIB TBR1 SNRNP200	1.41e-06	736	245	19	29676528
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ATP6V0A1 MYCBP2 SIPA1L3 FMNL2 STAT6 MAGI2 VPS35L CHD6 HSPA9 TARS1 DYNC1H1 SOX6 WARS1 REV3L SIM2 ZNF365 MSTO1 TARS3 TXNDC15 NISCH TSPAN7 ERC2 SCRIB SNRNP200 ECE2 JPH3	1.59e-06	1285	245	26	35914814
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	ETF1 EFTUD2 MDN1 HNRNPA0 UMPS PYCR2 HSPA9 TARS1 DYNC1H1 SEC23A UFL1 SIN3A MTOR TLN1 SCRIB SNRNP200 KDM1A	3.37e-06	638	245	17	33239621
Pubmed	Catalase expression in MCF-7 breast cancer cells is mainly controlled by PI3K/Akt/mTor signaling pathway.	PIK3CA CAT MTOR	3.42e-06	5	245	3	24630930
Pubmed	Comparison of expression patterns between CREB family transcription factor OASIS and proteoglycan core protein genes during murine tooth development.	SPOCK1 ACAN GPC2 CSPG4	6.80e-06	18	245	4	12684764
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	SERPINA4 AEBP1 ACAN COL6A3 COL15A1 APOB POSTN CSPG4	9.88e-06	146	245	8	27068509
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	MAG ATP6V0A1 MBP AK5 HSPA9 DYNC1H1 SEC23A ACSL6 SLC2A14 PEX5L OGDH MTOR SETBP1 SEPTIN11 ERC2 ATP2A3	9.97e-06	621	245	16	22794259
Pubmed	Longitudinal neuroanatomical and behavioral analyses show phenotypic drift and variability in the Ts65Dn mouse model of Down syndrome.	MAG MBP CSPG4	1.18e-05	7	245	3	32817053
Pubmed	Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16.	FAM234A HS3ST6 WDR90 SPSB3 RHBDF1 CAPN15	1.43e-05	74	245	6	11157797
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	ITGB4 SERPINA4 FAT2 FCGBP ACAN COL6A3 LAMP1 APOB POSTN CSPG4	1.59e-05	257	245	10	16335952
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	FAM234A VGLL3 ITGA5 PLXNB2 ADAM10 EFTUD2 MOGS VPS35L HSPA9 IGSF3 AMIGO2 AGTRAP LAMP1 CAT SIN3A TXNDC15 LMAN1 RDH11 CSPG4 ERC2 SLC39A14 M6PR SNRNP200	1.62e-05	1203	245	23	29180619
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	MYCBP2 SIPA1L3 ETF1 EFTUD2 MAGI2 MDN1 SVIL HSPA9 DYNC1H1 SEC23A GRIA4 PEX5L CELSR2 MTOR NISCH SEPTIN11 ERC2 SCRIB CDH10 KDM1A	1.86e-05	963	245	20	28671696
Pubmed	Role of the cellular prion protein in oligodendrocyte precursor cell proliferation and differentiation in the developing and adult mouse CNS.	MAG MBP CSPG4	1.88e-05	8	245	3	22529900
Pubmed	Transcription factors Sox5 and Sox6 exert direct and indirect influences on oligodendroglial migration in spinal cord and forebrain.	MBP SOX6 CSPG4	1.88e-05	8	245	3	26345464
Pubmed	Rheb1 is required for mTORC1 and myelination in postnatal brain development.	MAG MBP MTOR CSPG4	2.71e-05	25	245	4	21238928
Pubmed	BDNF+/- mice exhibit deficits in oligodendrocyte lineage cells of the basal forebrain.	MAG MBP CSPG4	2.81e-05	9	245	3	20091777
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	EFTUD2 NEK3 MDN1 PELO SVIL TARS1 SEC23A KIFC1 WARS1 MSTO1 MTOR SCRIB	3.06e-05	400	245	12	35013556
Pubmed	A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.	HDHD3 BIRC6 MDN1 PELO UMPS PYCR2 HSPA9 DYNC1H1 UFL1 NFS1 OGDH TARS3 RDH11 NISCH TBR1 MMUT	3.34e-05	686	245	16	28380382
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CSMD3 MAGI2 CHD6 DYNC1H1 ACSL6 FRAS1 ZNF365 NISCH TLN1 ERC2 SCRIB SLC39A14	3.62e-05	407	245	12	12693553
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	PSPH PLXNB2 ADAM10 EHD2 EFTUD2 MAGI2 MOGS AEBP1 PYCR2 DNAH6 HSPA9 SEC23A GLRX2 CAT SIN3A NFS1 OGDH LMAN1 DPP9 CELSR2 RDH11 TLN1 CSPG4 SLC39A14 SNRNP200	3.85e-05	1451	245	25	30550785
Pubmed	Harnessing host enhancers of SARS-CoV-2 entry as novel targets for antiviral therapy.	PLXNB2 ADAM10 ITGB4 MELTF IGSF3	4.35e-05	55	245	5	38945485
Pubmed	LSD1 coordinates with the SIN3A/HDAC complex and maintains sensitivity to chemotherapy in breast cancer.	SIN3A KDM1A	4.94e-05	2	245	2	29741645
Pubmed	Effect of targeted disruption of signal transducer and activator of transcription (Stat)4 and Stat6 genes on the autoimmune diabetes development induced by multiple low doses of streptozotocin.	STAT4 STAT6	4.94e-05	2	245	2	15721841
Pubmed	Differential effects of inhibitors of the PI3K/mTOR pathway on the expansion and functionality of regulatory T cells.	PIK3CA MTOR	4.94e-05	2	245	2	27189717
Pubmed	IRAS, the human homologue of Nischarin, prolongs survival of transfected PC12 cells.	ITGA5 NISCH	4.94e-05	2	245	2	12868002
Pubmed	STAT4 and STAT6, their role in cellular and humoral immunity and in diverse human diseases.	STAT4 STAT6	4.94e-05	2	245	2	39188021
Pubmed	The hypoxia sensitive metal transcription factor MTF-1 activates NCX1 brain promoter and participates in remote postconditioning neuroprotection in stroke.	MELTF SLC8A1	4.94e-05	2	245	2	33931586
Pubmed	The possible relationship between allergic manifestations and elevated serum levels of brain specific auto-antibodies in autistic children.	MAG MBP	4.94e-05	2	245	2	23726766
Pubmed	Susceptibility to Leishmania mexicana infection is due to the inability to produce IL-12 rather than lack of IL-12 responsiveness.	STAT4 STAT6	4.94e-05	2	245	2	11488977
Pubmed	Stat 4 but not Stat 6 mediated immune mechanisms are essential in protection against plague.	STAT4 STAT6	4.94e-05	2	245	2	15458778
Pubmed	Dual targeting of phosphoinositide 3-kinase and mammalian target of rapamycin using NVP-BEZ235 as a novel therapeutic approach in human ovarian carcinoma.	PIK3CA MTOR	4.94e-05	2	245	2	21372221
Pubmed	PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancer.	PIK3CA MTOR	4.94e-05	2	245	2	20479250
Pubmed	[PI3K and mTOR pathway and molecular targeted agents].	PIK3CA MTOR	4.94e-05	2	245	2	26281684
Pubmed	TLN1 synergizes with ITGA5 to ameliorate cardiac microvascular endothelial cell dysfunction.	ITGA5 TLN1	4.94e-05	2	245	2	37144848
Pubmed	Both gene expression for orotate phosphoribosyltransferase and its ratio to dihydropyrimidine dehydrogenase influence outcome following fluoropyrimidine-based chemotherapy for metastatic colorectal cancer.	UMPS DPYD	4.94e-05	2	245	2	14562021
Pubmed	Structural insights of a PI3K/mTOR dual inhibitor with the morpholino-triazine scaffold.	PIK3CA MTOR	4.94e-05	2	245	2	26956874
Pubmed	Upregulation of mTORC2 activation by the selective agonist of EPAC, 8-CPT-2Me-cAMP, in prostate cancer cells: assembly of a multiprotein signaling complex.	RAPGEF3 MTOR	4.94e-05	2	245	2	22173835
Pubmed	Periostin responds to mechanical stress and tension by activating the MTOR signaling pathway.	POSTN MTOR	4.94e-05	2	245	2	24349533
Pubmed	Using genomewide mutagenesis screens to identify the genes required for neural tube closure in the mouse.	TBC1D32 C2CD3	4.94e-05	2	245	2	15971254
Pubmed	Prognostic Significance of Periostin and Mammalian Target of Rapamycin (mTOR) in Locally Advanced Esophageal Squamous Cell Carcinoma.	POSTN MTOR	4.94e-05	2	245	2	28665915
Pubmed	KDM1A inhibition augments the efficacy of rapamycin for the treatment of endometrial cancer.	MTOR KDM1A	4.94e-05	2	245	2	34673129
Pubmed	Increased susceptibility of Stat4-deficient and enhanced resistance in Stat6-deficient mice to infection with Trypanosoma cruzi.	STAT4 STAT6	4.94e-05	2	245	2	10903759
Pubmed	Ehrlichia Activation of Wnt-PI3K-mTOR Signaling Inhibits Autolysosome Generation and Autophagic Destruction by the Mononuclear Phagocyte.	PIK3CA MTOR	4.94e-05	2	245	2	28993455
Pubmed	Epigenetic regulation of the alternatively activated macrophage phenotype.	STAT4 STAT6	4.94e-05	2	245	2	19567879
Pubmed	Signals mediating skeletal muscle remodeling by resistance exercise: PI3-kinase independent activation of mTORC1.	PIK3CA MTOR	4.94e-05	2	245	2	21071597
Pubmed	Pivotal role of Stat4 and Stat6 in the pathogenesis of the lupus-like disease in the New Zealand mixed 2328 mice.	STAT4 STAT6	4.94e-05	2	245	2	12874250
Pubmed	The STAT4 and STAT6 pathways in pancreatitis-associated lung injury.	STAT4 STAT6	4.94e-05	2	245	2	17109890
Pubmed	Dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor is an effective radiosensitizer for colorectal cancer.	PIK3CA MTOR	4.94e-05	2	245	2	25497009
Pubmed	Neonatal tolerance in the absence of Stat4- and Stat6- dependent Th cell differentiation.	STAT4 STAT6	4.94e-05	2	245	2	12370340
Pubmed	Superior efficacy of co-treatment with the dual PI3K/mTOR inhibitor BEZ235 and histone deacetylase inhibitor Trichostatin A against NSCLC.	PIK3CA MTOR	4.94e-05	2	245	2	27507059
Pubmed	IRAS is an anti-apoptotic protein.	ITGA5 NISCH	4.94e-05	2	245	2	15028619
Pubmed	Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells.	PIK3CA MTOR	4.94e-05	2	245	2	20857497
Pubmed	Disruption of the STAT4 signaling pathway protects from autoimmune diabetes while retaining antiviral immune competence.	STAT4 STAT6	4.94e-05	2	245	2	10553062
Pubmed	Periostin promotes chronic allergic inflammation in response to Th2 cytokines.	STAT6 POSTN	4.94e-05	2	245	2	22684102
Pubmed	STAT4 deficiency reduces autoantibody production and glomerulonephritis in a mouse model of lupus.	STAT4 STAT6	4.94e-05	2	245	2	16713741
Pubmed	A novel nuclear localization signal in the human single-minded proteins SIM1 and SIM2.	SIM1 SIM2	4.94e-05	2	245	2	14697214
Pubmed	Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets.	STAT4 STAT6	4.94e-05	2	245	2	11290331
Pubmed	Genomic Evolution after Chemoradiotherapy in Anal Squamous Cell Carcinoma.	PIK3CA FBXW7	4.94e-05	2	245	2	27852700
Pubmed	Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation.	STAT4 STAT6	4.94e-05	2	245	2	20620946
Pubmed	PIK3CA mutant tumors depend on oxoglutarate dehydrogenase.	PIK3CA OGDH	4.94e-05	2	245	2	28396387
Pubmed	A signal transducer and activator of transcription (Stat)4-independent pathway for the development of T helper type 1 cells.	STAT4 STAT6	4.94e-05	2	245	2	9743537
Pubmed	Orally induced peripheral nonresponsiveness is maintained in the absence of functional Th1 or Th2 cells.	STAT4 STAT6	4.94e-05	2	245	2	10227985
Pubmed	The Role of JAK-STAT-SOCS1 Axis in Tumorigenesis, Malignant Progression and Lymphatic Metastasis of Penile Cancer.	STAT4 SOCS1	4.94e-05	2	245	2	38774752
Pubmed	Agonist-driven development of CD4+CD25+Foxp3+ regulatory T cells requires a second signal mediated by Stat6.	STAT4 STAT6	4.94e-05	2	245	2	17548589
Pubmed	Defining Th1 and Th2 immune responses in a reciprocal cytokine environment in vivo.	STAT4 STAT6	4.94e-05	2	245	2	15034039
Pubmed	Developmental defects and rescue from glucose intolerance of a catalytically-inactive novel Ship2 mutant mouse.	INPPL1 PIK3CA	4.94e-05	2	245	2	22750293
Pubmed	Loss of threonyl-tRNA synthetase-like protein Tarsl2 has little impact on protein synthesis but affects mouse development.	TARS1 TARS3	4.94e-05	2	245	2	37059185
Pubmed	Neuron/Glial Antigen 2-Type VI Collagen Interactions During Murine Temporomandibular Joint Osteoarthritis.	COL6A3 CSPG4	4.94e-05	2	245	2	30635602
Pubmed	IL-12, while beneficial, is not essential for the host response to VSV encephalitis.	STAT4 STAT6	4.94e-05	2	245	2	12458040
Pubmed	Cutting edge: STAT6-deficient mice have enhanced tumor immunity to primary and metastatic mammary carcinoma.	STAT4 STAT6	4.94e-05	2	245	2	11086031
Pubmed	[Correlation between clinicopathological factors and enzymatic activity of orotate phosphoribosyl transferase (OPRT), dihydropyrimidine dehydrogenase (DPD) in esophageal cancer].	UMPS DPYD	4.94e-05	2	245	2	20647710
Pubmed	Identification of predicted human outer dynein arm genes: candidates for primary ciliary dyskinesia genes.	DNAH6 DNAH10	4.94e-05	2	245	2	15937072
Pubmed	Distinct requirements for Stat4 and Stat6 in hematopoietic progenitor cell responses to growth factors and chemokines.	STAT4 STAT6	4.94e-05	2	245	2	12965077
Pubmed	Cloning of two human homologs of the Drosophila single-minded gene SIM1 on chromosome 6q and SIM2 on 21q within the Down syndrome chromosomal region.	SIM1 SIM2	4.94e-05	2	245	2	9199934
Pubmed	Helicobacter pylori promotes eukaryotic protein translation by activating phosphatidylinositol 3 kinase/mTOR.	PIK3CA MTOR	4.94e-05	2	245	2	25194338
Pubmed	Single-minded--two genes, three chromosomes.	SIM1 SIM2	4.94e-05	2	245	2	9199929
Pubmed	The susceptibility to experimental myasthenia gravis of STAT6-/- and STAT4-/- BALB/c mice suggests a pathogenic role of Th1 cells.	STAT4 STAT6	4.94e-05	2	245	2	14688314
Pubmed	Overexpression of mSim2 gene in the zona limitans of the diencephalon of segmental trisomy 16 Ts1Cje fetuses, a mouse model for trisomy 21: a novel whole-mount based RNA hybridization study.	SIM1 SIM2	4.94e-05	2	245	2	10837894
Pubmed	LSD1 negatively regulates autophagy through the mTOR signaling pathway in ovarian cancer cells.	MTOR KDM1A	4.94e-05	2	245	2	29749504
Pubmed	Pivotal role of signal transducer and activator of transcription (Stat)4 and Stat6 in the innate immune response during sepsis.	STAT4 STAT6	4.94e-05	2	245	2	11257135
Pubmed	Novel targeting of phosphatidylinositol 3-kinase and mammalian target of rapamycin in renal cell carcinoma.	PIK3CA MTOR	4.94e-05	2	245	2	23867512
Pubmed	Oligodendrocyte precursor cells modulate the neuronal network by activity-dependent ectodomain cleavage of glial NG2.	ADAM10 CSPG4	4.94e-05	2	245	2	25387269
Pubmed	Induction of mitochondrial reactive oxygen species production by GSH mediated S-glutathionylation of 2-oxoglutarate dehydrogenase.	GLRX2 OGDH	4.94e-05	2	245	2	26928132
Pubmed	Dual inhibition of PI3K and mTOR signaling pathways decreases human pancreatic neuroendocrine tumor metastatic progression.	PIK3CA MTOR	4.94e-05	2	245	2	24263107
Pubmed	SPOCK1 and POSTN are valuable prognostic biomarkers and correlate with tumor immune infiltrates in colorectal cancer.	SPOCK1 POSTN	4.94e-05	2	245	2	36611136
Pubmed	CMIP and ATP2C2 modulate phonological short-term memory in language impairment.	ATP2C2 CMIP	4.94e-05	2	245	2	19646677
Pubmed	Different competitive capacities of Stat4- and Stat6-deficient CD4+ T cells during lymphophenia-driven proliferation.	STAT4 STAT6	4.94e-05	2	245	2	15661871
Pubmed	A threonyl-tRNA synthetase-like protein has tRNA aminoacylation and editing activities.	TARS1 TARS3	4.94e-05	2	245	2	29579307
Pubmed	STAT4/6-dependent differential regulation of chemokine receptors.	STAT4 STAT6	4.94e-05	2	245	2	16413227
Pubmed	Th2 cells are required for the Schistosoma mansoni egg-induced granulomatous response.	STAT4 STAT6	4.94e-05	2	245	2	9469446
Interaction	TOP3B interactions	MYCBP2 INPPL1 SIPA1L3 OBSCN MED14 ITGA5 NPHP4 PLXNB2 BIRC6 ITGB4 ABCA7 FBXL6 MDN1 MOGS SVIL HNRNPA0 WDR90 GPC2 DYNC1H1 SEC23A IGSF3 AGTRAP ANKRD13D FRAS1 RHBDF1 APOB ICE1 LRRK1 REV3L MST1R SEPHS2 C2CD3 CELSR2 MTOR IL17RE NISCH TLN1 CSPG4 DUSP16 ATP2A3	6.58e-07	1470	239	40	int:TOP3B
Interaction	C2CD4B interactions	ADGRV1 PLXNB2 SVIL FAT4 FRAS1 ICE1 CELSR2	7.97e-07	44	239	7	int:C2CD4B
Interaction	TRGV3 interactions	CNTNAP3B PLXNB2 ADAM10 MELTF FRAS1 CSPG4 CHRD	3.78e-06	55	239	7	int:TRGV3
Interaction	NEK4 interactions	ABCA13 MED14 CSMD3 NPHP4 ITGB4 EFTUD2 ACAN HNRNPA0 HSPA9 COL6A3 FAT4 FRAS1 PCDHGC5 APOB SEPHS2 TXNDC15 SETBP1 ATP2A3 SNRNP200 CAPN15	2.21e-05	582	239	20	int:NEK4
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	MASP1 CSMD3 SVEP1 ACAN CSMD1	1.75e-04	57	166	5	1179
GeneFamily	Cadherin related	CDHR2 FAT2 FAT4	4.70e-04	17	166	3	24
Coexpression	GSE46606_IRF4HIGH_VS_IRF4MID_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_DN	ATP6V0A1 MYCBP2 STAT6 EHD2 RFTN1 SOX6 WARS1 USB1 OGDH POSTN MTOR	2.65e-06	199	242	11	M9846
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	MYCBP2 SPOCK1 NPAS3 CSMD3 FMNL2 MAGI2 TBC1D32 FAT2 MDN1 MAST4 AJAP1 CACNA1I GPC2 SYT13 IGSF3 ACSL6 GRIA4 SIN3A REV3L PEX5L SLC4A1 SLC8A1 CMIP TSPAN7 ERC2 CSMD1 JPH3	4.44e-06	1106	242	27	M39071
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HNBGABA	MYCBP2 SPOCK1 NPAS3 CSMD3 TBC1D32 AJAP1 AK5 SYT13 ANKRD13D ACSL6 GRIA4 REV3L PEX5L SLC4A1 SLC8A1 CMIP TSPAN7 ERC2 CSMD1 JPH3	9.51e-06	703	242	20	M39070
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HPERIC	MFRP SVEP1 STAT4 STAT6 EHD2 RFTN1 MELTF PELO RAPGEF3 SVIL SLC38A11 SLC2A14 SLC4A1 SLC8A1 PLA2G4C GUCY1A2 TLN1 CSPG4 TSPAN7 SEPTIN11 M6PR	1.72e-05	795	242	21	M39050
Coexpression	GSE3039_NKT_CELL_VS_B1_BCELL_UP	ATP6V0A1 ABCA13 SIPA1L3 ITGA5 FGF20 UBP1 CMIP LAMTOR4 DUSP16 ATP2A3	1.74e-05	199	242	10	M6432
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 OBSCN ADGRV1 CSMD3 MELTF ADAMTS16 SDK1 FAT4 FRAS1 DNAH10 APOB FIGN SLC8A1 CSMD1	1.93e-12	184	243	14	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 OBSCN ADGRV1 CSMD3 MELTF ADAMTS16 SDK1 FAT4 FRAS1 DNAH10 APOB FIGN SLC8A1 CSMD1	1.93e-12	184	243	14	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 OBSCN ADGRV1 CSMD3 MELTF ADAMTS16 SDK1 FAT4 FRAS1 DNAH10 APOB FIGN SLC8A1 CSMD1	1.93e-12	184	243	14	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NCALD RFTN1 AEBP1 ACAN SVIL COL6A3 COL15A1 FIGN ATP10A POSTN SLC8A1 GUCY1A2	9.30e-10	196	243	12	1522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NCALD RFTN1 AEBP1 ACAN SVIL COL6A3 COL15A1 FIGN ATP10A POSTN SLC8A1 GUCY1A2	9.30e-10	196	243	12	1c8294014713684b50885e638668f2ce75f357f0
ToppCell	moderate-Lymphoid-NK\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	GCK HHATL AEBP1 COL6A3 FAT4 COL15A1 POSTN CSPG4 SLC39A14 HAS2 RNF133	6.40e-09	185	243	11	4979a787acbc9b4ca8defe91cc79b674e51af1bf
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPOCK1 ABCA13 ADGRV1 MAGI2 MELTF FCGBP SLC38A11 FRAS1 CAT SIM1 SIM2	7.16e-09	187	243	11	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPOCK1 ADGRV1 MELTF FCGBP MAST4 SLC38A11 FRAS1 CAT SIM1 SIM2 ERC2	8.46e-09	190	243	11	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	MAGI2 MAST4 SVIL SDK1 SOX6 FRAS1 PARD3B SLC8A1 CMIP SETBP1 RBM6	9.43e-09	192	243	11	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NCALD SVEP1 RFTN1 AEBP1 CACNA1I COL6A3 COL15A1 FIGN PLA2G4C GUCY1A2 HAS2	1.05e-08	194	243	11	90efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NCALD SVEP1 RFTN1 AEBP1 CACNA1I COL6A3 COL15A1 FIGN PLA2G4C GUCY1A2 HAS2	1.05e-08	194	243	11	df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	VGLL3 SVEP1 MAGI2 AEBP1 ADAMTS16 SDK1 COL6A3 COL15A1 POSTN SETBP1 SEPTIN11	1.23e-08	197	243	11	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	VGLL3 SVEP1 RFTN1 MDN1 AEBP1 COL6A3 FAT4 COL15A1 RFX2 GUCY1A2 HAS2	1.30e-08	198	243	11	a860246bcea847249a78fd2e86ed8e04371060db
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2--L2-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B NDST4 ADCY8 HHATL TMEM132C MAGI2 ACAN SDK1 SOX6 POSTN CHRD	1.44e-08	200	243	11	c65e6336725856c4b5f6aeba1cf86a23ec815d34
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B NDST4 ADCY8 HHATL TMEM132C MAGI2 ACAN SDK1 SOX6 POSTN CHRD	1.44e-08	200	243	11	117a25b3b9cdbc2e198381350a8362bee25e82e7
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B NDST4 ADCY8 HHATL TMEM132C MAGI2 ACAN SDK1 SOX6 POSTN CHRD	1.44e-08	200	243	11	d459e51507bf26865e6e7e04411379ec82a3edf8
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDHR2 ABCA13 NDST4 ADGRV1 CSMD3 CES4A FRAS1 DNAH10 ATP13A5 SIM1	2.21e-08	162	243	10	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 ADGRV1 CSMD3 AEBP1 DNAH6 FRAS1 DNAH10 ATP13A5 GRIA4 PLA2G4C	3.31e-08	169	243	10	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ADGRV1 SVEP1 STAT4 STRADA WDR90 ANKRD13D COL6A3 DPYD ATP10A CSPG4	3.50e-08	170	243	10	ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCell	droplet-Heart-nan-3m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VGLL3 ITGB4 MAGI2 FIGN PEX5L CELSR2 MTOR TBCK GAN CSMD1	6.00e-08	180	243	10	da723df348d7b8449bb1124f23fe6fa706412adb
ToppCell	droplet-Heart-nan-3m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VGLL3 ITGB4 MAGI2 FIGN PEX5L CELSR2 MTOR TBCK GAN CSMD1	6.00e-08	180	243	10	50758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCell	droplet-Heart-nan-3m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VGLL3 ITGB4 MAGI2 FIGN PEX5L CELSR2 MTOR TBCK GAN CSMD1	6.00e-08	180	243	10	5b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPOCK1 ADGRV1 MELTF FCGBP MAST4 SLC38A11 FRAS1 CAT SIM1 SIM2	9.97e-08	190	243	10	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	droplet-Kidney-nan-18m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VGLL3 SVEP1 AJAP1 AEBP1 AK5 SYT13 COL6A3 COL15A1 GRIA4 CSMD1	1.10e-07	192	243	10	38d7a24ae205ef91ed2e0f402d8022f2a9cdb243
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VGLL3 SVEP1 AJAP1 AEBP1 AK5 SYT13 COL6A3 COL15A1 GRIA4 CSMD1	1.10e-07	192	243	10	04d155897ed075c359933080e36a4ab2150b6e9f
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ABCA13 NEK10 ADGRV1 ATP2C2 HS3ST6 CES4A DNAH6 SDK1 DNAH10 FRMPD2	1.15e-07	193	243	10	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	VGLL3 SVEP1 TMEM132C MAGI2 SDK1 COL6A3 FRAS1 GUCY1A2 SETBP1 SEPTIN11	1.21e-07	194	243	10	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NCALD SVEP1 RFTN1 AEBP1 COL6A3 COL15A1 FIGN GUCY1A2 SETBP1 PTCH2	1.27e-07	195	243	10	3c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CSMD3 EHD2 COL6A3 FAT4 COL15A1 WARS1 GRIA4 POSTN CMIP HAS2	1.40e-07	197	243	10	236a40eb6c08e1d179cf0fb5450b032975c5f6b6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NCALD SVEP1 RFTN1 AEBP1 COL6A3 COL15A1 FIGN ATP10A GUCY1A2 CSPG4	1.46e-07	198	243	10	79576525a10ed3e3a9d1608077cd16ecda23376f
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA13 OBSCN ITGB4 FAT2 SDK1 IGSF3 SOX6 FRAS1 POSTN CSMD1	1.53e-07	199	243	10	94a7867e800df352731796de8c24cba133c29622
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	VGLL3 SVEP1 TMEM132C MAGI2 AEBP1 SDK1 COL6A3 FAT4 GUCY1A2 SETBP1	1.53e-07	199	243	10	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_ALM_Olfr111_Nxph1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ITGA5 RFTN1 HPCAL1 SERPINB11 SVIL HS3ST6 FRMPD2 ATP10A	3.66e-07	122	243	8	dba1c647172a11381efcb178a23808161908daa3
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NCALD RFTN1 GRIA4 FIGN POSTN GUCY1A2 CSPG4 ERC2 HAS2	4.18e-07	170	243	9	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	FLU-Healthy-5\|Healthy / Virus stimulation, Condition and Cluster	KANSL1L CDHR2 PSPH MAST4 AEBP1 IGSF3 ZFP28 RFX2 SOCS1	4.84e-07	173	243	9	8c218ec1ba927e9312f3df5f312395e907ab64ab
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXNB2 STAT6 PELO SLC38A11 AMIGO2 ATP13A5 GUCY1A2 CSPG4 ATP2A3	4.84e-07	173	243	9	2acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXNB2 STAT6 PELO SLC38A11 AMIGO2 ATP13A5 GUCY1A2 CSPG4 ATP2A3	4.84e-07	173	243	9	2415b6ff49f334da570577d4e93484d024a3dbd5
ToppCell	FLU-Healthy-5\|FLU / Virus stimulation, Condition and Cluster	KANSL1L CDHR2 PSPH MAST4 AEBP1 IGSF3 ZFP28 RFX2 SOCS1	4.84e-07	173	243	9	bd4f06d971f9d138749094047c9337dfbaf5da31
ToppCell	NS-moderate-d_07-13-Lymphoid-NK\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	B4GALNT1 GCK HHATL AEBP1 FAT4 COL15A1 FIGN CSPG4 SLC39A14	5.33e-07	175	243	9	f6cd24d22f62469319f9d244e3e5de527d3d4d94
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2-Inh_L1-6_PVALB_SCUBE3_(Chandelier_1)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B VGLL3 ADCY8 TMEM132C MELTF SVIL SDK1 SOX6 COL15A1	5.59e-07	176	243	9	95d5a4fdff1b9c715636684d22e06f8727ac0e7a
ToppCell	cellseq2-Mesenchymal-Myocytic-Myocytic_1\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MASP1 BCORL1 GCK RFTN1 VPS35L SLC38A11 KIAA1614 GUCY1A2 SEPTIN11	5.86e-07	177	243	9	e415e448c37adc102d766235e9953dec32c021f1
ToppCell	cellseq2-Mesenchymal-Myocytic-Myocytic_1-Pericyte\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MASP1 BCORL1 GCK RFTN1 VPS35L SLC38A11 KIAA1614 GUCY1A2 SEPTIN11	5.86e-07	177	243	9	68263456a3c93cd195b321b309ff59e156d732fe
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NCALD SVEP1 RFTN1 AEBP1 COL6A3 COL15A1 FIGN GUCY1A2 SETBP1	6.15e-07	178	243	9	78a0c6340001a77f5b2d890b6263f574af2e72da
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B VGLL3 ADCY8 TMEM132C MELTF SVIL SDK1 SOX6 COL15A1	6.44e-07	179	243	9	3b0f8781232e1d42b6f8913bc989a14b3f978e79
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBP ITGB4 AJAP1 SOX6 FIGN PEX5L POSTN CCDC87 CSMD1	6.75e-07	180	243	9	dad458398683ff80a6e207bdc08e257d1bb757d6
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBP ITGB4 AJAP1 SOX6 FIGN PEX5L POSTN CCDC87 CSMD1	6.75e-07	180	243	9	d9c9399df3e2d9f23dbbfffb6cbe8404bf01e2b7
ToppCell	NS-moderate-d_16-33-Lymphoid-NK\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GCK AEBP1 COL6A3 COL15A1 POSTN GUCY1A2 CHRD SLC39A14 HAS2	7.40e-07	182	243	9	fb503f8ecd013f1f2161a5841572b57cfcddb6fa
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBP ITGB4 AJAP1 SOX6 FIGN PEX5L POSTN CCDC87 CSMD1	7.40e-07	182	243	9	812ff2a50a510b18d865e89465dba1754a08ef61
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SVOPL AJAP1 ACAN SOX6 FIGN PEX5L POSTN CSPG4 CSMD1	7.40e-07	182	243	9	a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B ADCY8 HHATL TMEM132C ACAN SDK1 SOX6 POSTN CHRD	7.75e-07	183	243	9	04d3cc76038b8192c915f1c08c3e26f2ad3b3779
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBP CSMD3 AJAP1 SOX6 FIGN PEX5L POSTN CSMD1 CDH10	8.88e-07	186	243	9	d8d559daff4aeef334d403fde4e3ee2e4a6086d0
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	VGLL3 SVEP1 TMEM132C ACAN COL6A3 FRAS1 FIGN POSTN HAS2	9.28e-07	187	243	9	f1d0fc625e0e7881b3f290742fd7148d995eb71e
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	VGLL3 SVEP1 TMEM132C ACAN COL6A3 FRAS1 FIGN POSTN HAS2	9.28e-07	187	243	9	02e7246ef5ad41773d14426254e139b156d45c1d
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	VGLL3 SVEP1 TMEM132C ACAN COL6A3 FRAS1 FIGN POSTN HAS2	9.28e-07	187	243	9	08c73d125e0638c9e9878165bba2442c266c8a48
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B ADCY8 HHATL TMEM132C ACAN SDK1 SOX6 POSTN ECE2	9.70e-07	188	243	9	8de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MASP1 NCALD OBSCN RFTN1 FIGN GUCY1A2 CSPG4 CHRD SEPTIN11	9.70e-07	188	243	9	ee151792c7ac9afe820f1a281c6dab383799f358
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-chondrocyte\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	NPAS3 SVEP1 ACAN ITIH6 AMIGO2 COL15A1 FIGN CSPG4 SETBP1	9.70e-07	188	243	9	c9270517e6940e9793586f67f02431210552f278
ToppCell	10x5'v1-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	NPAS3 ADCY8 SDK1 COL6A3 COL15A1 ZNF365 POSTN GUCY1A2 SOCS1	1.01e-06	189	243	9	473b01c9162b12b90a617c600238436177a0d18d
ToppCell	moderate-Lymphoid-NK\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	HHATL AEBP1 FAT4 FIGN POSTN CSPG4 SLC39A14 HAS2 RNF133	1.01e-06	189	243	9	22a19365782003c18ec8dddcdbfdaa82c4e330f6
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D175\|Adult / Lineage, Cell type, age group and donor	VGLL3 SPOCK1 SVEP1 AEBP1 ADAMTS16 COL6A3 GUCY1A2 SETBP1 SLC39A14	1.06e-06	190	243	9	7dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B ADCY8 HHATL TMEM132C ACAN SDK1 SOX6 POSTN CHRD	1.06e-06	190	243	9	e58e4b6fbeb4368f738adac67ec10879c0966f0f
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Artery\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RPS6KA5 ITGA5 ITGB4 PTPRB SMIM2 SOX6 LRRK1 SLC8A1 CSMD1	1.06e-06	190	243	9	aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBP CSMD3 AJAP1 SOX6 FIGN PEX5L POSTN CSMD1 CDH10	1.06e-06	190	243	9	ff3dec5b45c6ea9b5319fb51a0198c6773b7be26
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBP CSMD3 AJAP1 SOX6 FIGN PEX5L POSTN CSMD1 CDH10	1.06e-06	190	243	9	4971857eac9af17d66d673ed2ab7072639f60a10
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Artery\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RPS6KA5 ITGB4 PTPRB SMIM2 SOX6 FAT4 LRRK1 SLC8A1 CSMD1	1.11e-06	191	243	9	4b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VGLL3 SVEP1 TMEM132C MAGI2 AEBP1 SDK1 COL6A3 GUCY1A2 SETBP1	1.16e-06	192	243	9	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VGLL3 SVEP1 AEBP1 AK5 SYT13 COL6A3 COL15A1 GRIA4 CSMD1	1.16e-06	192	243	9	84149a5c6c3b3c9b86aed77cf8e72d99ef099fab
ToppCell	LPS_only-Stromal_mesenchymal\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SVEP1 TMEM132C MAGI2 AEBP1 SDK1 COL6A3 GUCY1A2 SETBP1 HAS2	1.16e-06	192	243	9	162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NCALD SVEP1 RFTN1 AEBP1 COL6A3 COL15A1 FIGN ATP10A GUCY1A2	1.21e-06	193	243	9	f1199518c3626fd29bfce65070dd21a660671213
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VGLL3 SVEP1 TMEM132C MAGI2 SDK1 COL6A3 GUCY1A2 SETBP1 CDH10	1.21e-06	193	243	9	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	VGLL3 SVEP1 TMEM132C MAGI2 SDK1 COL6A3 FAT4 FRAS1 SETBP1	1.21e-06	193	243	9	acad568621ed677031797b8c2e34dafea798d681
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SVEP1 TMEM132C MAGI2 AEBP1 SDK1 COL6A3 FIGN SETBP1 HAS2	1.21e-06	193	243	9	261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NCALD SVEP1 RFTN1 AEBP1 COL6A3 FIGN GUCY1A2 SETBP1 PTCH2	1.26e-06	194	243	9	81713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VGLL3 SVEP1 TMEM132C MAGI2 SDK1 COL6A3 GUCY1A2 SETBP1 HAS2	1.26e-06	194	243	9	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NCALD SVEP1 RFTN1 AEBP1 COL6A3 FIGN GUCY1A2 SETBP1 PTCH2	1.26e-06	194	243	9	627cffe2d448e74fc5df92e74e5b922a73304137
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NCALD SVEP1 RFTN1 AEBP1 COL6A3 FIGN GUCY1A2 SETBP1 PTCH2	1.26e-06	194	243	9	cf0244a29934e515446ac917d3c30672b460fb04
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NCALD SVEP1 RFTN1 AEBP1 COL6A3 COL15A1 FIGN GUCY1A2 SETBP1	1.26e-06	194	243	9	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NCALD SVEP1 RFTN1 AEBP1 COL6A3 FIGN GUCY1A2 SETBP1 PTCH2	1.26e-06	194	243	9	ba7f971fb9a19423602da60770f23d9fead4a451
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	VGLL3 SVEP1 RFTN1 AEBP1 COL6A3 COL15A1 ATP10A POSTN GUCY1A2	1.31e-06	195	243	9	dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NCALD SVEP1 RFTN1 AEBP1 COL6A3 COL15A1 FIGN ATP10A GUCY1A2	1.31e-06	195	243	9	edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCell	COVID-19-kidney-Fibroblast-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SPOCK1 SVEP1 SDK1 COL6A3 COL15A1 REV3L FIGN GUCY1A2 SETBP1	1.31e-06	195	243	9	3d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	VGLL3 SVEP1 RFTN1 AEBP1 COL6A3 COL15A1 ATP10A POSTN GUCY1A2	1.31e-06	195	243	9	49c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	KANSL1L SIPA1L3 MAST4 SDK1 SOX6 FRAS1 PARD3B SIM1 SIM2	1.31e-06	195	243	9	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 NDST4 ADGRV1 CSMD3 CES4A FRAS1 ATP13A5 SIM1	1.36e-06	145	243	8	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NEK10 SIPA1L3 MAST4 SLC38A11 SDK1 SOX6 FRAS1 PARD3B SIM1	1.37e-06	196	243	9	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NCALD SVEP1 RFTN1 COL6A3 COL15A1 REV3L FIGN PLA2G4C GUCY1A2	1.37e-06	196	243	9	2b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCell	RA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	SPOCK1 FMNL2 TMEM132C COL6A3 COL15A1 PARD3B REV3L SETBP1 HAS2	1.37e-06	196	243	9	e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	VGLL3 SVEP1 AEBP1 COL6A3 FAT4 COL15A1 RFX2 ATP10A GUCY1A2	1.43e-06	197	243	9	9b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NCALD SVEP1 RFTN1 AEBP1 COL6A3 COL15A1 FIGN GUCY1A2 SETBP1	1.43e-06	197	243	9	ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NCALD SVEP1 RFTN1 AEBP1 COL6A3 COL15A1 FIGN GUCY1A2 SETBP1	1.43e-06	197	243	9	37f6b6f2809b952382eaebb642b0aad6371f4251
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	VGLL3 SVEP1 MAGI2 AEBP1 SDK1 COL6A3 PARD3B POSTN SETBP1	1.43e-06	197	243	9	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	VGLL3 SVEP1 TMEM132C MAGI2 COL6A3 FAT4 GUCY1A2 SETBP1 SEPTIN11	1.49e-06	198	243	9	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	MYCBP2 SVEP1 SDK1 COL6A3 REV3L LMAN1 SOCS1 SLC39A14 HAS2	1.55e-06	199	243	9	fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SPOCK1 GDF6 CSMD3 TMEM132C ATP2C2 CSPG4 TSPAN7 CSMD1 CDH10	1.55e-06	199	243	9	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NPAS3 SVEP1 ACAN SOX6 COL6A3 FAT4 SIM2 SEPTIN11 SLC39A14	1.55e-06	199	243	9	abd6117f8a3d7e798d8471c16d97b34aaf50fc9c
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	RFTN1 PELO ACAN SLC38A11 POSTN SLC8A1 GUCY1A2 CSPG4 SEPTIN11	1.62e-06	200	243	9	4e1e19214aeebbdca004de7faaf4cc9d18498591
ToppCell	Skin-Fibroblasts\|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.	MASP1 SPOCK1 ITGA5 SVEP1 AEBP1 COL6A3 CHRD SEPTIN11 HAS2	1.62e-06	200	243	9	f777eadf571a1a6d246da87346a9cb9d511c2e81
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2\|Control_saline / Treatment groups by lineage, cell group, cell type	PLXNB2 RFTN1 PELO COL6A3 POSTN SLC8A1 GUCY1A2 CSPG4 HAS2	1.62e-06	200	243	9	bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NEK10 ADGRV1 ADCY8 SLC38A11 SYT13 AMIGO2 SIM1 CCDC87	2.24e-06	155	243	8	498e52e2364ff44d3c0c707ba22468217031f5bd
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRV1 ADCY8 SVEP1 FRAS1 DNAH10 ATP13A5 GRIA4 SIM2	2.84e-06	160	243	8	c381ec6be8cf887861cc18f831a20db42f953fe1
Drug	arachidonyl trifluoromethyl ketone; Up 200; 10uM; MCF7; HG-U133A	ATP6V0A1 MED14 NEU3 ITGA5 ACAN SPSB3 SYT13 RALB CASP2 GRIA4 UFL1 APOB MST1R	2.51e-07	198	245	13	594_UP
Drug	Flumequine [42835-25-6]; Up 200; 15.4uM; MCF7; HT_HG-U133A	MASP1 ATP6V0A1 SVEP1 STAT6 MAGI2 MAST4 CACNA1I CASP2 MST1R PLA2G4C GUCY1A2 MTOR	1.61e-06	197	245	12	5529_UP
Disease	Malignant neoplasm of breast	BCORL1 OBSCN MED14 ADAM10 STAT4 PIK3CA UMPS GPC2 TMEM125 DPYD WARS1 CAT SIM1 RFX2 ZNF365 LIPE TXNDC15 GUCY1A2 MTOR NISCH SETBP1 ATP2A3 CDH10 FBXW7	7.81e-06	1074	239	24	C0006142
Disease	Colorectal Carcinoma	ABCA13 OBSCN CSMD3 ADCY8 PIK3CA UMPS DPYD FRMPD2 APOB PEX5L POSTN GUCY1A2 SETBP1 B4GALNT2 SNRNP200 JPH3 FBXW7	6.58e-05	702	239	17	C0009402
Disease	gastric adenocarcinoma (is_marker_for)	STAT6 HNRNPA0 AMIGO2 CAT	7.38e-05	28	239	4	DOID:3717 (is_marker_for)
Disease	cataract (biomarker_via_orthology)	ADAM10 SLC2A14 CAT	1.41e-04	13	239	3	DOID:83 (biomarker_via_orthology)
Disease	Malformations of Cortical Development	PIK3CA DYNC1H1 MTOR	1.79e-04	14	239	3	C1955869
Disease	Cortical Dysplasia	PIK3CA DYNC1H1 MTOR	1.79e-04	14	239	3	C0431380
Disease	rectum adenocarcinoma (is_implicated_in)	STAT4 STAT6	1.95e-04	3	239	2	DOID:1996 (is_implicated_in)
Disease	breast angiosarcoma (is_implicated_in)	PTPRB PIK3CA	1.95e-04	3	239	2	DOID:4511 (is_implicated_in)
Disease	arthritis	BCO1 GAN	1.95e-04	3	239	2	EFO_0005856
Disease	alcohol consumption measurement	RPS6KA5 CHDH NPAS3 ADGRV1 CSMD3 FMNL2 BIRC6 STAT6 MAGI2 PTPRB MAST4 AK5 CACNA1I WDR90 SDK1 HID1 MST1R SLC8A1 PLA2G4C MTOR SETBP1 CSMD1 ECE2	2.09e-04	1242	239	23	EFO_0007878
Disease	Macrostomia	FRAS1 PTCH2	3.88e-04	4	239	2	C0024433
Disease	amino acid metabolic disorder (implicated_via_orthology)	TARS1 TARS3	3.88e-04	4	239	2	DOID:9252 (implicated_via_orthology)
Disease	Malignant Head and Neck Neoplasm	STAT6 PIK3CA DPYD FANCL	4.42e-04	44	239	4	C0278996
Disease	Renal Cell Carcinoma	CSMD3 PIK3CA HSPA9 CASP2 MTOR M6PR	6.32e-04	128	239	6	C0007134
Disease	Sarcomatoid Renal Cell Carcinoma	CSMD3 PIK3CA HSPA9 CASP2 MTOR M6PR	6.32e-04	128	239	6	C1266043
Disease	Chromophobe Renal Cell Carcinoma	CSMD3 PIK3CA HSPA9 CASP2 MTOR M6PR	6.32e-04	128	239	6	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	CSMD3 PIK3CA HSPA9 CASP2 MTOR M6PR	6.32e-04	128	239	6	C1266044
Disease	Papillary Renal Cell Carcinoma	CSMD3 PIK3CA HSPA9 CASP2 MTOR M6PR	6.32e-04	128	239	6	C1306837
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	ADCY8 MAGI2 ACAN AK5 DPYD DNAH10 PARD3B SIM1 MST1R SETBP1	8.28e-04	364	239	10	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	Behcet Syndrome	STAT4 CAT APOB	9.37e-04	24	239	3	C0004943
Disease	Age-related cataract	CMIP GAN	9.59e-04	6	239	2	HP_0011141
Disease	congenital muscular dystrophy (implicated_via_orthology)	DYNC1H1 COL6A3	9.59e-04	6	239	2	DOID:0050557 (implicated_via_orthology)
Disease	Hemimegalencephaly	PIK3CA MTOR	9.59e-04	6	239	2	C0431391
Disease	age at menarche	VGLL3 NDST4 WDR25 ADCY8 MAGI2 DPYD SIM1 CMIP RBM6 ERC2 GAN CSMD1 ECE2	1.20e-03	594	239	13	EFO_0004703
Disease	neurodegenerative disease (implicated_via_orthology)	DYNC1H1 FAT4 GRIA4 OGDH TSPAN7 PTCH2	1.21e-03	145	239	6	DOID:1289 (implicated_via_orthology)
Disease	Mammary Carcinoma, Human	ADAM10 PIK3CA UMPS DPYD CAT SIM1 ZNF365 GUCY1A2 MTOR NISCH SETBP1 FBXW7	1.28e-03	525	239	12	C4704874
Disease	Mammary Neoplasms, Human	ADAM10 PIK3CA UMPS DPYD CAT SIM1 ZNF365 GUCY1A2 MTOR NISCH SETBP1 FBXW7	1.28e-03	525	239	12	C1257931
Disease	Mammary Neoplasms	ADAM10 PIK3CA UMPS DPYD CAT SIM1 ZNF365 GUCY1A2 MTOR NISCH SETBP1 FBXW7	1.32e-03	527	239	12	C1458155
Disease	platelet reactivity measurement, thrombus formation measurement	SVIL SETBP1	1.34e-03	7	239	2	EFO_0004985, EFO_0007615
Disease	LDL cholesterol change measurement	APOB CELSR2	1.34e-03	7	239	2	EFO_0007804
Disease	catalase measurement	CAT CELSR2	1.34e-03	7	239	2	EFO_0008071
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	CSMD3 PIK3CA HSPA9 CASP2 MTOR M6PR	1.34e-03	148	239	6	C0279702
Disease	Adenoid Cystic Carcinoma	BCORL1 ITGB4 MAGI2 PIK3CA FBXW7	1.35e-03	100	239	5	C0010606
Disease	gastroesophageal reflux disease	SDK1 DPYD APOB RBM6 CSMD1	1.41e-03	101	239	5	EFO_0003948
Disease	gait measurement	NCALD NPAS3 WDR25 IGSF3 SIM1 MST1R	1.44e-03	150	239	6	EFO_0007680
Disease	Pigmented Basal Cell Carcinoma	PIK3CA PTCH2 FBXW7	1.48e-03	28	239	3	C1368275
Disease	Breast Carcinoma	ADAM10 PIK3CA UMPS DPYD CAT SIM1 ZNF365 GUCY1A2 MTOR NISCH SETBP1 FBXW7	1.57e-03	538	239	12	C0678222
Disease	hippocampus volume change measurement, age at assessment	TMEM132C NEK3 LRRK1	1.64e-03	29	239	3	EFO_0008007, EFO_0021492
Disease	Carcinoma, Basal Cell	PIK3CA PTCH2 FBXW7	1.64e-03	29	239	3	C4721806
Disease	Meckel syndrome (implicated_via_orthology)	NPHP4 TBC1D32	1.77e-03	8	239	2	DOID:0050778 (implicated_via_orthology)
Disease	esterified cholesterol measurement, intermediate density lipoprotein measurement	APOB CELSR2	1.77e-03	8	239	2	EFO_0008589, EFO_0008595
Disease	Hereditary spherocytosis	UMPS SLC4A1	1.77e-03	8	239	2	C0037889
Disease	renal tubular acidosis (implicated_via_orthology)	ATP6V0A1 SLC4A1	1.77e-03	8	239	2	DOID:14219 (implicated_via_orthology)
Disease	Calcium channel blocker use measurement	TBC1D19 CHDH SVEP1 SOX6 FIGN CMIP B4GALNT2	1.83e-03	213	239	7	EFO_0009930
Disease	obesity (implicated_via_orthology)	GCK PLXNB2 STAT4 SDK1 FAT4 DNAH10 SIM1	1.93e-03	215	239	7	DOID:9970 (implicated_via_orthology)
Disease	total lipids in large VLDL	DNAH10 APOB CMIP CELSR2	2.16e-03	67	239	4	EFO_0022175
Disease	bone fracture	RPS6KA5 SVIL SOX6 COL15A1 SLC8A1	2.22e-03	112	239	5	EFO_0003931
Disease	body fat percentage	ADCY8 MAGI2 ACAN AK5 DPYD DNAH10 PARD3B SIM1 SLC4A1 MST1R SETBP1	2.25e-03	488	239	11	EFO_0007800
Disease	free cholesterol in large VLDL measurement	DNAH10 APOB CMIP CELSR2	2.28e-03	68	239	4	EFO_0022265
Disease	neuritic plaque measurement	MBP NPAS3 SVEP1 TMEM132C ICE1 BCO1 CMIP GAN CSMD1	2.29e-03	349	239	9	EFO_0006798
Disease	Disease Exacerbation	ABCA13 ABCA7 PIK3CA CAT M6PR KDM1A	2.33e-03	165	239	6	C0235874
Disease	Head and Neck Neoplasms	STAT6 PIK3CA DPYD	2.39e-03	33	239	3	C0018671
Disease	triglyceride measurement, low density lipoprotein cholesterol measurement	GCK ADAM10 DNAH10 APOB CMIP CELSR2	2.40e-03	166	239	6	EFO_0004530, EFO_0004611
Disease	Beta blocking agent use measurement	NCALD SOX6 FIGN CMIP CELSR2	2.40e-03	114	239	5	EFO_0009929
Disease	diastolic blood pressure, alcohol drinking	NEK10 SAXO2 FER1L5 SOX6 FIGN	2.79e-03	118	239	5	EFO_0004329, EFO_0006336
Disease	Methylmalonic acidemia	SEPTIN11 MMUT	2.82e-03	10	239	2	C0268583
Disease	response to carboplatin, response to antineoplastic agent	CMIP CSMD1	2.82e-03	10	239	2	GO_0097327, GO_0097328
Disease	Congenital Disorders of Glycosylation	FCSK MOGS	2.82e-03	10	239	2	C0282577
Disease	serine measurement	PSPH DYNC1H1 OGDH	2.84e-03	35	239	3	EFO_0009774
Disease	Liver carcinoma	STAT4 SERPINA4 PIK3CA UMPS HSPA9 KIFC1 DPYD COL15A1 MTOR CSPG4 CSMD1	3.01e-03	507	239	11	C2239176
Disease	juvenile idiopathic arthritis	ABCA13 NPHP4 STAT4 FANCL	3.10e-03	74	239	4	EFO_0002609
Disease	Semantic-Pragmatic Disorder	DPYD SETBP1	3.42e-03	11	239	2	C0454655
Disease	Methylmalonic aciduria	SEPTIN11 MMUT	3.42e-03	11	239	2	C1855119
Disease	Auditory Processing Disorder, Central	DPYD SETBP1	3.42e-03	11	239	2	C0751257
Disease	level of Diacylglycerol (18:1_18:1) in blood serum	APOB B4GALNT2	3.42e-03	11	239	2	OBA_2045170
Disease	Language Delay	DPYD SETBP1	3.42e-03	11	239	2	C0023012
Disease	Language Development Disorders	DPYD SETBP1	3.42e-03	11	239	2	C0023014
Disease	degenerative disc disease (biomarker_via_orthology)	ACAN POSTN	3.42e-03	11	239	2	DOID:90 (biomarker_via_orthology)
Disease	Speech Delay	DPYD SETBP1	3.42e-03	11	239	2	C0241210
Disease	heart disease (implicated_via_orthology)	SOX6 LIPE ATP2A3	3.59e-03	38	239	3	DOID:114 (implicated_via_orthology)
Disease	hepatocellular carcinoma (is_implicated_in)	SPOCK1 STAT4 EFTUD2 PIK3CA CAT SOCS1	3.68e-03	181	239	6	DOID:684 (is_implicated_in)
Disease	Malignant Neoplasms	BIRC6 PIK3CA DPYD CAT MTOR	3.95e-03	128	239	5	C0006826
Disease	microphthalmia (implicated_via_orthology)	GDF6 MFRP	4.09e-03	12	239	2	DOID:10629 (implicated_via_orthology)
Disease	esophageal cancer (is_marker_for)	PIK3CA SOCS1	4.09e-03	12	239	2	DOID:5041 (is_marker_for)
Disease	free cholesterol in medium LDL measurement	PELO APOB CELSR2	4.16e-03	40	239	3	EFO_0022268
Disease	clinical treatment	MYCBP2 CHDH APOB	4.46e-03	41	239	3	EFO_0007056
Disease	Congenital small ears	GDF6 EFTUD2 FRAS1	4.46e-03	41	239	3	C0152423
Disease	retinitis pigmentosa (is_implicated_in)	MFRP CAT SNRNP200	4.46e-03	41	239	3	DOID:10584 (is_implicated_in)
Disease	congestive heart failure (is_marker_for)	RAPGEF3 CAT POSTN MTOR	4.48e-03	82	239	4	DOID:6000 (is_marker_for)
Disease	Hodgkins lymphoma	FCGBP CACNA1I ATP13A5 ERC2	4.48e-03	82	239	4	EFO_0000183
Disease	language measurement	MAG RFTN1 ATP13A5 HID1 CMIP	4.79e-03	134	239	5	EFO_0007797
Disease	Fetal Alcohol Spectrum Disorders	PIK3CA CAT	4.80e-03	13	239	2	C2985290
Disease	childhood gender nonconformity	FGF20 AMIGO2 SIM2	5.10e-03	43	239	3	EFO_0020103
Disease	cholesteryl esters to total lipids in small HDL percentage	ADAM10 APOB CELSR2	5.10e-03	43	239	3	EFO_0022254
Disease	Bagassosis	ACAN HS3ST6	5.58e-03	14	239	2	C0004681
Disease	esterified cholesterol measurement, low density lipoprotein cholesterol measurement	APOB CELSR2	5.58e-03	14	239	2	EFO_0004611, EFO_0008589
Disease	Pneumoconiosis	ACAN HS3ST6	5.58e-03	14	239	2	C0032273
Disease	glycodeoxycholate measurement	SVIL CSMD1	5.58e-03	14	239	2	EFO_0010493
Disease	descending aortic diameter	MASP1 STAT6 SVIL COL6A3	5.75e-03	88	239	4	EFO_0021788
Disease	bronchopulmonary dysplasia	SPOCK1 CSMD3 MAGI2	5.80e-03	45	239	3	MONDO_0019091
Disease	homocysteine measurement	PSPH CSMD1 MMUT	6.16e-03	46	239	3	EFO_0004578
Disease	Agents acting on the renin-angiotensin system use measurement	TBC1D19 SVEP1 SOX6 FIGN CMIP CELSR2 B4GALNT2 ERC2	6.23e-03	335	239	8	EFO_0009931
Disease	schizophrenia (biomarker_via_orthology)	MBP KDM1A	6.40e-03	15	239	2	DOID:5419 (biomarker_via_orthology)
Disease	cortex volume change measurement	MAGI2 PARD3B	6.40e-03	15	239	2	EFO_0021500
Disease	response to statin, LDL cholesterol change measurement	APOB CELSR2	6.40e-03	15	239	2	EFO_0007804, GO_0036273
Disease	Hypertriglyceridemia	APOB CELSR2	6.40e-03	15	239	2	C0020557
Disease	amenorrhea, response to antineoplastic agent	ADCY8 APOB	6.40e-03	15	239	2	EFO_0010269, GO_0097327
Disease	sleep duration, low density lipoprotein cholesterol measurement	MAGI2 APOB OGDH CELSR2	6.47e-03	91	239	4	EFO_0004611, EFO_0005271
Disease	vision disorder	MAGI2 SDK1	7.27e-03	16	239	2	MONDO_0021084
Disease	response to triptolide, cytotoxicity measurement	NEK10 CSMD1	7.27e-03	16	239	2	EFO_0006952, EFO_0007662

Protein segments in the cluster

Peptide	Gene	Start	Entry
FVTRLEAVTSNHDGG	SYT13	176	Q7L8C5
SFNNFELRIGISHGS	ADCY8	1081	P40145
LGVDGESGFLLHVTR	FAM234A	256	Q9H0X4
SDIHQTFGLGLTSEE	ATP13A5	161	Q4VNC0
GESLRVDTSLLGFEH	ANKRD13D	151	Q6ZTN6
IHILSTERGAFQTGQ	BIRC6	2816	Q9NR09
RLEFQSDHSTTGRGF	CSMD1	671	Q96PZ7
GIHLRTRSFQLFEGD	CSMD1	1141	Q96PZ7
GSRIHLSFNDFDLES	CSMD3	756	Q7Z407
TLDGGFRFRLSDGEH	CSPG4	1551	Q6UVK1
ESLHQVSFLFSDRGI	CAT	191	P04040
SHIFGLRDFIIDGLS	TBC1D32	851	Q96NH3
AQSRGELLHSLEGFL	SLC4A1	301	P02730
SRVAHLEFFLDGLGS	B4GALNT1	456	Q00973
AHSEFFIDGLGTLLV	B4GALNT2	496	Q8NHY0
HGSVIDGRFEGFIQT	ADAM10	116	O14672
GVITQGRDSSIHDDF	AEBP1	456	Q8IUX7
GDFSHLGSRDLALSV	CARMIL2	196	Q6F5E8
ISDEFSEAIGALRGH	EHD2	196	Q9NZN4
DGTFDLTVLSNDGVH	FAT4	3676	Q6V0I7
FLSDHLSDLQGRAEG	BCORL1	1611	Q5H9F3
SFQTASRSVIGHEGE	ADGRV1	2706	Q8WXG9
KRHLQGDGLSSFDSR	AJAP1	156	Q9UKB5
TQFGDAGLRLLSEHL	CMIP	696	Q8IY22
SRAGNFDVAFLTHLL	ABCA13	2176	Q86UQ4
IDSAESGLQFLHSGA	DPYD	796	Q12882
IINGSFRALGFIHEA	AMIGO2	286	Q86SJ2
ATRLLAHESTQRGFG	CELSR2	2081	Q9HCU4
EQLHLGLYGTSDRLT	FBXL6	411	Q8N531
RNFLDSFHIEGAGAL	CCDC87	451	Q9NVE4
DVLRHFSVTAEGGLS	ATP2A3	11	Q93084
GLSEFSVTQRRLAHG	ATP2C2	76	O75185
RLTFELLHTLGFDSV	ATP10A	731	O60312
EDTGLGLAFTIAHES	ADAMTS16	421	Q8TE57
TGAHDGSFATLFREL	ABCA7	1106	Q8IZY2
QHLSGFGAEREATLT	ACAD11	31	Q709F0
GATAHLETGGFIRSQ	CHDH	376	Q8NE62
GEGFLLVFSITEHES	RALB	86	P11234
IVNDSLHGLTDGVFI	RFTN1	341	Q14699
LHGLTDGVFIFEAVS	RFTN1	346	Q14699
GGLGLREHFDFVLTS	HDHD3	146	Q9BSH5
FHGEASEQLRTRGAF	GCK	316	P35557
RFILGSAHDADIGSN	PCDHGB4	151	Q9UN71
QLEGNAGFSITHRLA	CAPN15	1036	O75808
ELAVLFRTDHGISSG	MFRP	391	Q9BY79
EGLGFTVVTRDSSIH	PARD3B	391	Q8TEW8
FSIRHLAFVDLGNST	OR8K5	61	Q8NH50
LVQRTEGFSGLDVAH	FIGN	681	Q5HY92
GLTARDNEGATALHF	ESPNL	231	Q6ZVH7
THSGELSNESFIFGR	PTPRB	1156	P23467
SDIHSNELAIFFEGG	OR1B1	196	Q8NGR6
HSSGAEFILAGLTQR	OR8D2	6	Q9GZM6
FSATGLLSHVEEGLD	KANSL1L	326	A0AUZ9
LQAFIEGSSLGEFHV	MDN1	3871	Q9NU22
EFQFSLTDGLHVDTG	FRAS1	2051	Q86XX4
TGTFDLQEVLFHGGS	HHATL	166	Q9HCP6
LQEVLFHGGSSFTVL	HHATL	171	Q9HCP6
GTLTSFDIHILRAFG	MAGED4	46	Q96JG8
IGSETSLIIHRGGFF	MAGI2	671	Q86UL8
VHESFQGRSRLLGDL	MAG	81	P20916
ELHTISFLGGLALNE	DOLPP1	56	Q86YN1
GTDEDLAHSSIRFGI	NFS1	396	Q9Y697
GFTHLSTGELLREEL	AK5	401	Q9Y6K8
GISRQSFHEGALGVE	LRRK1	1411	Q38SD2
RGLVEDSGSFLVHTL	GPC2	86	Q8N158
IVIDLSDSAGIGFRH	IL17RE	16	Q8NFR9
DAGQGTFHRLVGSLD	KIAA1614	506	Q5VZ46
VFQLQISGEHSSRGL	KIFC1	541	Q9BW19
LGTLSNSRDFLRHFG	ECE2	781	P0DPD6
DISLERFIHGGANVT	GRIA4	246	P48058
NNHTVAFLGTSDGRI	PLXNB2	401	O15031
LQGDRNFVSDHSSIG	NEK10	341	Q6ZWH5
TGLGSEFFRLLHDLH	FAM157A	146	C9JC47
AEGHFSIDATTGVIR	FAT2	3156	Q9NYQ8
GSTQTHFILLGFSDR	OR2W3	6	Q7Z3T1
DFILVGLFSHSGSRQ	OR2Z1	11	Q8NG97
FGDHTSEAVRNLFGL	PCDHGC5	281	Q9Y5F6
REVLTLQLGHFAGFV	MSTO1	6	Q9BUK6
LQTGLGVLFHLSGEF	PEX5L	476	Q8IYB4
GVLFHLSGEFNRAID	PEX5L	481	Q8IYB4
RLGIFGFLSTDDSHA	CES4A	171	Q5XG92
GSFSLGEQSRVISHF	DCAF11	146	Q8TEB1
EHVFRTFDTNGDGTI	HPCAL1	66	P37235
NHLGLEGARIISDFF	LRRC74A	171	Q0VAA2
GGLADDHDVLSFLTF	LMAN1	251	P49257
HREGTFNDTLRLIGE	KIR2DS3	61	Q14952
GGELFTHLSQRERFT	RPS6KA5	136	O75582
SGNRGAEHFTIELTE	ERC2	246	O15083
TTFSQLRELHLEGNF	LRRC20	71	Q8TCA0
TLFATVIQDLGLHDG	NDST4	251	Q9H3R1
TFLGGEDFDQALLRH	HSPA9	271	P38646
TFEDITRAFEGQAHG	SLC2A14	481	Q8TDB8
LEAGGSLTRHVTQEF	ITGB4	1786	P16144
VATFILGIGDRHNSN	PIK3CA	906	P42336
GEGSFGRALLVQHES	NEK3	11	P51956
ELEEGGSFSTRIRSH	MCIDAS	341	D6RGH6
GTLRFQFSLGSEEHL	NPHP4	441	O75161
VSGHLDFSGQLSGDR	ACAN	876	P16112
FHEANLERSSGLGVS	ACAN	2136	P16112
VQVEGDGFSHAIRLL	MED14	671	O60244
SGHTSELGDFRFTLL	MOGS	231	Q13724
STEVTEFHLLGFGVQ	OR5AK3P	6	Q8NH89
GREREGSFHSNDLFL	GIMAP5	211	Q96F15
EAGGQRLSFHLDVSE	OBSCN	1331	Q5VST9
ALGHLSLAEVGTEEF	OBSCN	5521	Q5VST9
LTLTGHDEFGRFGSS	ITGA5	381	P08648
IRLSGQDVERGTFSH	OGDH	671	Q02218
TREVHLILSFDFSAG	PLA2G4C	401	Q9UP65
EQLLRTFGGGFELHT	FCSK	816	Q8N0W3
GVEFSHRLNTDIAGL	APOB	1861	P04114
GDSEHLFRILANGSI	CDHR2	171	Q9BYE9
LTLERLSQLHVFDFG	DNAH6	991	Q9C0G6
EFHDLVTFTRDGGVQ	IGSF3	591	O75054
FERHVSGGLFSLTVQ	IGSF3	756	O75054
VLVQSHRDGGSTEFV	ICE1	306	Q9Y2F5
DDFEFTGSHLTVRNG	KDM1A	556	O60341
GGLELSISFTHRGDR	C2CD3	1361	Q4AC94
TDLDRIFNIHSGNGS	CDH10	426	Q9Y6N8
SITFLSEIFLRGIHG	CHD6	496	Q8TD26
LFSTGLAHRGLEDTD	DDX51	451	Q8N8A6
TGEERRLTFCHQGLS	DPP9	216	Q86TI2
QHGSDVVIETDFGLR	FCGBP	1351	Q9Y6R7
EESGFLIEAIRSTHG	CYP2A7	151	P20853
AAGSLSFQGRVSHIE	FRMPD2	66	Q68DX3
NGRSTEGLIFQEVLH	FRMPD2	1136	Q68DX3
FAEHLLGAGFVSSRN	DHX36	801	Q9H2U1
RINHGVLSAEGFLFV	GAN	316	Q9H2C0
GELTIIDNLSGSIFH	CACNA1I	1816	Q9P0X4
NSVHLLAGGFAEFSR	DUSP16	116	Q9BY84
LDFVVENHFTRAGGS	COL6A3	326	P12111
SLQFDGIHVVSGSLD	FBXW7	546	Q969H0
FGDDRHLTNRVLSLG	HAS2	311	Q92819
VNGTFIGGATDTHRL	GLRX2	126	Q9NS18
FLTGHGRLSEQQVDR	CARD19	16	Q96LW7
VRGGHEIILSAFDNF	FMNL2	276	Q96PY5
HRDTGILDSIGRFFG	MBP	166	P02686
GELEHGLITFSTRNN	MASP1	371	P48740
SVGSFSEHLDQINGR	MAST4	1031	O15021
GEHTLLVTVSGQRVF	LAMTOR4	71	Q0VGL1
QALGHRVSLFSLAFG	ITIH6	416	Q6UXX5
QHFLRGNEIVLSAGS	DYNC1H1	3906	Q14204
FRDGVLLDGATFHQT	KIRREL2	161	Q6UWL6
VIAFGRGHTLTLNFT	LAMP1	91	P11279
LGLNFHVSVLGETFT	GTDC1	311	Q4AE62
GLERFTGSLQQLTVH	COL15A1	211	P39059
GVGLVFEADLFTTRH	DNAH10	4441	Q8IVF4
GERHIFDGNSLLLSR	PIWIL3	171	Q7Z3Z3
LDNGGFAALELSSRH	SDK1	2056	Q7Z5N4
TLSDGLHNFIDGLAI	SLC39A14	341	Q15043
ENVFIGRHFIIGLST	SLC38A11	91	Q08AI6
EHVFRTFDANGDGTI	NCALD	66	P61601
LEFRSGGDVDHSTLV	CASP2	216	P42575
HLLFGELQRGSGSFV	CNTNAP3B	406	Q96NU0
LSHFLFVSGERLVSD	HS3ST6	241	Q96QI5
FLQTISIGLVSFGEH	LIPE	481	Q05469
FRIIDSDHSGFISLD	PPEF2	661	O14830
GNGVLIIASIFDSHF	OR13C3	71	Q8NGS6
LRTLGSFEFEGHSLT	MTOR	586	P42345
NGFDALLEHIRTSFG	GUCY1A2	201	P33402
QGTRQDHSLFGILEF	FGF20	86	Q9NP95
TITSFVDRGLDDLSH	GDF6	126	Q6KF10
FGVLHRNELSGTLSG	TARS3	516	A2RTX5
DFGVLHRNELSGALT	TARS1	436	P26639
AFSGGRDTIEEHRQF	WARS1	376	P23381
ALTEGLEILSGNHFS	RDH11	271	Q8TC12
SQLDFRGRDIHSGDF	RBM6	111	P78332
HVLSELGETGVFGRS	RNF133	51	Q8WVZ7
HSGIFGLVTNLEELE	STRADA	411	Q7RTN6
GLSGREAHEEINITF	TMEM248	146	Q9NWD8
VLDGVSELRHSFDGS	TBR1	86	Q16650
EELRNLSLSGHVGFD	SEPTIN11	11	Q9NVA2
LNEGQRLFSHEGSSF	MELTF	296	P08582
AIFGRLTEHNETILF	SVIL	1661	O95425
EGHGVTDNIQRFSSL	TMEM132C	31	Q8N3T6
EGFISAQGRDFHLRI	FANCL	26	Q9NW38
VIDLENRLLSGFGAH	FER1L5	1571	A0AVI2
DLGSFLLQDGVTLHD	RFX2	351	P48378
HSRSQILEGLGFNLT	SERPINA4	96	P29622
GFNLTELSESDVHRG	SERPINA4	106	P29622
EFTVHVALGFLTTQG	PTCH2	1031	Q9Y6C5
GLTDESEILRFLQHG	HID1	716	Q8IV36
VFLHENGEEGSLSLA	SMG1	2751	Q96Q15
SFFAREGILHEELST	RHBDF1	261	Q96CC6
GSHLLQTLDGFVFVV	SIM2	81	Q14190
GRGDHIFLQATEGSV	SIPA1L3	931	O60292
GSHLLQTLDGFIFVV	SIM1	81	P81133
QFLTFLSHRGEETGN	INPPL1	851	O15357
FRLDNTLGGTSEVIH	SIN3A	651	Q96ST3
GSHALLVAEDGSIFF	MYCBP2	591	O75592
GSHILQSLDGFVFAL	NPAS3	151	Q8IXF0
ALHFLESGGFRSLLI	PYCR2	241	Q96C36
GTVRIFSSLHVSGEQ	PELO	341	Q9BRX2
FAAGIGHRNSLESIS	SCRIB	1211	Q14160
GELFLLLDSRGAFHT	SKIV2L	501	Q15477
SSRFGQGSIIGVHLD	SPSB3	211	Q6PJ21
ELNTRAFHVGAFGEL	SNAPC3	36	Q92966
GRIHSEFGVEFSQIN	SERPINB11	81	Q96P15
ENGFLEHTTGRIFES	SVEP1	2211	Q4LDE5
QAGRFHLDGSRESFD	SOCS1	131	O15524
IDTEHGGSQARFLLS	SEC23A	706	Q15436
DAVETIGFGRFHIAL	SVOPL	36	Q8N434
SLSFHSVFEGLAVGL	SLC39A2	171	Q9NP94
GLSDRFGRNLDTFEH	SOX6	341	P35712
DLTGGAFEDNLRSLH	B3GNTL1	336	Q67FW5
GFSVRHALSGNLTDF	ADGRD2	261	Q7Z7M1
FDGLALLHSFTIRDG	BCO1	51	Q9HAY6
VADRAEFLGSGLLQH	ACSL6	126	Q9UKU0
SDTEDSLHFLLLFRG	CHRD	306	Q9H2X0
ELLVHTGFLGSSQDR	AGTRAP	116	Q6RW13
STDHGEGFQRLALSR	NEU3	256	Q9UQ49
QALFQHGGDVSRALT	RNF31	596	Q96EP0
VLETRGHAISILFGF	SMIM2	16	Q9BVW6
VTTLHEGDDFGQLAL	RAPGEF3	301	O95398
RELTGSLFSGQRSVH	ZFP28	291	Q8NHY6
LRHGGLSLVQTTDFF	SEPHS2	126	Q99611
LVDTGEQRFFLGHTD	WDR90	396	Q96KV7
GLSFFNSILAHGDLR	VPS35L	891	Q7Z3J2
QASGFVRDLSGHVLT	ZNF365	296	Q70YC5
DGEGFSSIHLAVLFQ	ZDHHC13	146	Q8IUH4
TVVGRLNETHIFNGS	M6PR	101	P20645
LFGIQFLHVLTRGSQ	REV3L	2546	O60673
FLISGGFRSIVEHVA	PSPH	106	P78330
VQTSESGLRGHFEAF	HNRNPA0	16	Q13151
SGLRGHFEAFGTLTD	HNRNPA0	21	Q13151
AGTLNREGTETFADH	TLN1	2001	Q9Y490
LLRFSESHLGGITFT	STAT4	596	Q14765
LRFSDSEIGGITIAH	STAT6	561	P42226
LALEQFTGHDGVRDS	TECPR1	631	Q7Z6L1
LDARIFHTEFGSGVA	VPS16	131	Q9H269
ELGGQFLDLSLHDTV	VPS16	686	Q9H269
VRESLFSLDGAGAHF	TXNDC15	126	Q96J42
NVGLFDQHFRLTGST	NISCH	1236	Q9Y2I1
FLQVESRHLDALAGG	SPOCK1	16	Q08629
EEHSEFVVGFISGSR	UMPS	391	P11172
VGTLSDIFGNLHLDS	SRRD	101	Q9UH36
GFRHVDQDGLELLTS	REL	311	Q04864
NSEDFIRGHISGSIN	TBCK	801	Q8TEA7
IGLEVTSGHAQFLDL	USB1	171	Q9BQ65
LTTHRCDFQGLIGET	SAXO2	181	Q658L1
TGNFQVTELGRIASH	SNRNP200	976	O75643
DSIQFALRRGTEHSG	ATP6V0A1	331	Q93050
IESGLVHDFDASLSG	UBP1	11	Q9NZI7
RILSGGFDFALHLTD	WDR25	306	Q64LD2
GFDFALHLTDLETGT	WDR25	311	Q64LD2
LHLTDLETGTQLFSG	WDR25	316	Q64LD2
FGFETDLRTHTQGQA	EFTUD2	881	Q15029
TSDILEALGRDGHFT	POSTN	256	Q15063
GDIGSVVDEHFSRAL	VGLL3	96	A8MV65
DRILGTHDNLSGLFA	SETBP1	1161	Q9Y6X0
ENGDSLSFRTHLGLI	TBC1D19	171	Q8N5T2
AELVAGISGFVFRHE	TSPAN7	101	P41732
IFSISGQLSAGRRHE	TMEM125	196	Q96AQ2
DVSRLGDHLLFASGD	MST1R	501	Q04912
SGHIDLDNRGVIFTE	UFL1	166	O94874
DQTTLQGFLTHFLRE	TMEM260	251	Q9NX78
ALFGTLQGNTREVLH	ETF1	156	P62495
VSRGGFVLVAHSDSE	JPH3	191	Q8WXH2
IGLLTAFIGDLASHF	SLC8A1	811	P32418
QQGLSVAFDLATHRG	MMUT	131	P22033