Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Cadherin_CS	PCDHB10 PCDHA11 PCDH20 CDH24 PCDHB1 CDH18	6.36e-05	109	117	6	IPR020894
Domain	CADHERIN_1	PCDHB10 PCDHA11 PCDH20 CDH24 PCDHB1 CDH18	7.78e-05	113	117	6	PS00232
Domain	Cadherin	PCDHB10 PCDHA11 PCDH20 CDH24 PCDHB1 CDH18	7.78e-05	113	117	6	PF00028
Domain	CADHERIN_2	PCDHB10 PCDHA11 PCDH20 CDH24 PCDHB1 CDH18	8.17e-05	114	117	6	PS50268
Domain	-	PCDHB10 PCDHA11 PCDH20 CDH24 PCDHB1 CDH18	8.17e-05	114	117	6	2.60.40.60
Domain	CA	PCDHB10 PCDHA11 PCDH20 CDH24 PCDHB1 CDH18	8.58e-05	115	117	6	SM00112
Domain	Cadherin-like	PCDHB10 PCDHA11 PCDH20 CDH24 PCDHB1 CDH18	9.00e-05	116	117	6	IPR015919
Domain	Cadherin	PCDHB10 PCDHA11 PCDH20 CDH24 PCDHB1 CDH18	9.89e-05	118	117	6	IPR002126
Domain	FAST_2	FASTKD5 FASTKD2	5.74e-04	6	117	2	PF08368
Domain	RAP	FASTKD5 FASTKD2	5.74e-04	6	117	2	SM00952
Domain	FAST_Leu-rich	FASTKD5 FASTKD2	5.74e-04	6	117	2	IPR010622
Domain	RAP	FASTKD5 FASTKD2	5.74e-04	6	117	2	PF08373
Domain	RAP	FASTKD5 FASTKD2	5.74e-04	6	117	2	PS51286
Domain	FAST_1	FASTKD5 FASTKD2	5.74e-04	6	117	2	PF06743
Domain	FAST_2	FASTKD5 FASTKD2	5.74e-04	6	117	2	IPR013579
Domain	RAP	FASTKD5 FASTKD2	5.74e-04	6	117	2	IPR013584
Domain	Cadherin_2	PCDHB10 PCDHA11 PCDH20 PCDHB1	7.38e-04	65	117	4	PF08266
Domain	Cadherin_N	PCDHB10 PCDHA11 PCDH20 PCDHB1	7.38e-04	65	117	4	IPR013164
Domain	ATPase_dyneun-rel_AAA	VWA8 DNAH2	3.37e-03	14	117	2	IPR011704
Domain	AAA_5	VWA8 DNAH2	3.37e-03	14	117	2	PF07728
Domain	LRR_8	RSU1 IGSF10 RXFP2 SCRIB LRRC28	4.46e-03	171	117	5	PF13855
Domain	AMP-bd_C	SLC27A6 ACSM4	4.98e-03	17	117	2	IPR025110
Domain	AMP-binding_C	SLC27A6 ACSM4	4.98e-03	17	117	2	PF13193
Domain	Leu-rich_rpt_typical-subtyp	RSU1 IGSF10 RXFP2 SCRIB LRRC28	5.15e-03	177	117	5	IPR003591
Domain	LRR_TYP	RSU1 IGSF10 RXFP2 SCRIB LRRC28	5.15e-03	177	117	5	SM00369
Domain	C1_1	DGKH ARAF RASGRP1	5.48e-03	57	117	3	PF00130
Domain	ARM-type_fold	VPS11 DOHH ARMC3 RTTN WDFY4 AP1G2 ATM	5.51e-03	339	117	7	IPR016024
Domain	PI3/4_kinase_cat_dom	PI4K2B ATM	5.58e-03	18	117	2	IPR000403
Domain	PI3_PI4_kinase	PI4K2B ATM	5.58e-03	18	117	2	PF00454
Domain	PI3_4_KINASE_3	PI4K2B ATM	5.58e-03	18	117	2	PS50290
Domain	PI3_4_KINASE_1	PI4K2B ATM	5.58e-03	18	117	2	PS00915
Domain	PI3_4_KINASE_2	PI4K2B ATM	5.58e-03	18	117	2	PS00916
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	PI4K2B CACNA2D1 BMP2K VWA8 RNF213 LAMC1 FASTKD5 ECSIT NPM3 MYOF SF3B3 DST FAM120A LMO7 EIF2B1 GEMIN4 ATM USP39 SCRIB EXOC2 FAR1 CNOT1 PCM1 SOAT1	1.27e-10	1440	120	24	30833792
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CDKL2 DNAH2 RNF213 DGKH IGSF10 DST P4HA1 CCDC87 ATM USP39 SCRIB CNOT1 ITPRIPL1	1.69e-06	736	120	13	29676528
Pubmed	CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.	RNF213 ARAF P4HA1 ATM EXOC2 FAR1	1.71e-06	104	120	6	31240132
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	LAMC1 PIGV MYOF DST WASF2 SCRIB CNOT1 ITPRIPL1 PCM1	2.44e-06	332	120	9	37433992
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	NES TUT7 NVL RNF213 FASTKD5 FAM120A P4HA1 EIF2B1 ALG9 SECISBP2 ITPRIPL1 PCM1	9.30e-06	733	120	12	34672954
Pubmed	Multiple cadherin mRNA expression and developmental regulation of a novel cadherin in the developing mouse eye.	CDH24 CDH18	1.18e-05	2	120	2	10328938
Pubmed	ATM phosphorylation of the actin-binding protein drebrin controls oxidation stress-resistance in mammalian neurons and C. elegans.	DBN1 ATM	1.18e-05	2	120	2	30700723
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	DMXL2 VWA8 UTP14A NVL LAMC1 FASTKD5 FASTKD2 ECSIT RSU1 SF3B3 FAM120A P4HA1 ATM SCRIB FAR1 PCM1 SOAT1	1.43e-05	1487	120	17	33957083
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	VMA21 BMP2K VWA8 TUT7 UTP14A RNF213 FASTKD5 DGKH FASTKD2 ECSIT ARAF DST FAM120A RPUSD3 GEMIN4 SECISBP2 SOAT1	1.55e-05	1496	120	17	32877691
Pubmed	MiRNA-128 regulates the proliferation and neurogenesis of neural precursors by targeting PCM1 in the developing cortex.	NES PCM1	3.53e-05	3	120	2	26883496
Pubmed	Vascular Endothelial Growth Factor Receptor 3 Regulates Endothelial Function Through β-Arrestin 1.	FLT4 ARRB1	3.53e-05	3	120	2	30586762
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	UTP14A NVL FASTKD2 NPM3 SF3B3 DST FAM120A RPUSD3 SECISBP2 USP39 PCM1	4.34e-05	723	120	11	34133714
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	NES CACNA2D1 UTP14A LAMC1 SF3B3 DST LMO7 CPNE3 USP39 SCRIB FAR1 CNOT1 PCM1	5.55e-05	1024	120	13	24711643
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	GDPD1 VPS11 VWA8 TUT7 NVL FASTKD5 ECSIT LMO7 P4HA1 EIF2B1 PCM1	6.31e-05	754	120	11	33060197
Pubmed	Hook3 interacts with PCM1 to regulate pericentriolar material assembly and the timing of neurogenesis.	NES PCM1	7.05e-05	4	120	2	20152126
Pubmed	Adrenocortical lipid depletion gene (ald) in AKR mice is associated with an acyl-CoA:cholesterol acyltransferase (ACAT) mutation.	SERPINC1 SOAT1	7.05e-05	4	120	2	9422770
Pubmed	Prolonged RXFP1 and RXFP2 signaling can be explained by poor internalization and a lack of beta-arrestin recruitment.	ARRB1 RXFP2	7.05e-05	4	120	2	19279230
Pubmed	Mapping of Abll within a conserved linkage group on distal mouse chromosome 1 syntenic with human chromosome 1 using an interspecific cross.	LAMC1 SERPINC1	7.05e-05	4	120	2	2567701
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DMXL2 TUT7 UTP14A ARAF DST FAM120A WASF2 CPNE3 CARD6 SCRIB	8.92e-05	650	120	10	38777146
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	NES TUT7 UTP14A NVL DST FAM120A GEMIN4 ATM CNOT1 PCM1	9.27e-05	653	120	10	22586326
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	LAMC1 ARAF DST GEMIN4 FAR1 CNOT1 PCM1 ZMYM5	1.06e-04	418	120	8	34709266
Pubmed	Retinal axon misrouting at the optic chiasm in mice with neural tube closure defects.	NES SCRIB	1.17e-04	5	120	2	10862153
Pubmed	A critical function of the pial basement membrane in cortical histogenesis.	NES LAMC1	1.17e-04	5	120	2	12122064
Pubmed	Mitochondrial RNA Granules Are Centers for Posttranscriptional RNA Processing and Ribosome Biogenesis.	FASTKD5 FASTKD2	1.17e-04	5	120	2	25683715
Pubmed	The FASTK family of proteins: emerging regulators of mitochondrial RNA biology.	FASTKD5 FASTKD2	1.17e-04	5	120	2	29036396
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	UTP14A FASTKD5 FASTKD2 DBN1 NPM3 SF3B3 FAM120A EIF2B1 GEMIN4 ATM USP39 FAR1 BSN CNOT1 SOAT1	1.20e-04	1425	120	15	30948266
Pubmed	Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.	PCDHB10 PCDHA11 PCDH20 PCDHB1	1.29e-04	74	120	4	10817752
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NES DLGAP2 CACNA2D1 DMXL2 DBN1 DST FAM120A WASF2 SCRIB BSN CNOT1 PCM1	1.29e-04	963	120	12	28671696
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	IL12RB2 VWA8 RNF213 FASTKD5 ARAF NPM3 SF3B3 FAM120A TAF9B P4HA1 SCRIB FAR1 PCM1	1.31e-04	1116	120	13	31753913
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	PCDHB10 PCDHA11 PCDH20 PCDHB1	1.50e-04	77	120	4	10835267
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	PCDHB10 PCDHA11 PCDH20 PCDHB1	1.74e-04	80	120	4	10716726
Pubmed	Sequence and organization of the mouse poly (ADP-ribose) polymerase gene.	LAMC1 SERPINC1	1.75e-04	6	120	2	2498841
Pubmed	Fast kinase domain-containing protein 3 is a mitochondrial protein essential for cellular respiration.	FASTKD5 FASTKD2	1.75e-04	6	120	2	20869947
Pubmed	A Y2H-seq approach defines the human protein methyltransferase interactome.	VPS11 UTP14A JMJD4 UBA3 AK8 AP1G2 ZMYM5	1.92e-04	342	120	7	23455924
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	SF3B3 LMO7 CPNE3 GEMIN4 ATM USP39 SCRIB EXOC2 CNOT1	1.95e-04	582	120	9	20467437
Pubmed	Defining the membrane proteome of NK cells.	PI4K2B GDPD1 NVL RNF213 FAM120A P4HA1 ALG9 PXMP2 GEMIN4 EXOC2 CNOT1 ITPRIPL1 PCM1	2.04e-04	1168	120	13	19946888
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	BMP2K UTP14A DBN1 RSU1 MYOF SF3B3 FAM120A LMO7 SECISBP2 CNOT1	2.14e-04	724	120	10	36232890
Pubmed	HAUSP regulates c-MYC expression via de-ubiquitination of TRRAP.	CACNA2D1 DBN1 SF3B3	2.22e-04	34	120	3	25925205
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	NES TUT7 UTP14A FASTKD2 NPM3 SF3B3 DST FAM120A CPNE3 GEMIN4 AP1G2 SCRIB EXOC2 FAR1	2.44e-04	1353	120	14	29467282
Pubmed	The isolation and characterization of the murine T cell antigen receptor zeta chain gene.	LAMC1 SERPINC1	2.45e-04	7	120	2	2787796
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	CACNA2D1 VMA21 TUT7 RNF213 LAMC1 XYLT2 IGSF10 MYOF P4HA1 ALG9 ATM SCRIB SOAT1	2.67e-04	1201	120	13	35696571
Pubmed	Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept.	B3GALT5 BSN	3.26e-04	8	120	2	19567891
Pubmed	Genetic, morphometric, and behavioral factors linked to the midsagittal area of the corpus callosum.	VWA8 DGKH	3.26e-04	8	120	2	22666227
Pubmed	Linkage of genes for laminin B1 and B2 subunits on chromosome 1 in mouse.	LAMC1 SOAT1	3.26e-04	8	120	2	2993224
Pubmed	Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain.	NES DBN1 ATM	3.34e-04	39	120	3	22802532
Pubmed	ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.	BMP2K RNF213 MYOF SF3B3 LMO7 PCM1	3.47e-04	268	120	6	33024031
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	NES DMXL2 VWA8 UTP14A DBN1 SF3B3 DST P4HA1 CPNE3 ATM USP39 CNOT1	3.74e-04	1082	120	12	38697112
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	UTP14A DBN1 SF3B3 FAM120A LMO7 SCRIB	3.90e-04	274	120	6	34244482
Pubmed	Rufy3, a protein specifically expressed in neurons, interacts with actin-bundling protein Fascin to control the growth of axons.	NES DBN1	4.18e-04	9	120	2	24720729
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	BMP2K UTP14A DBN1 SF3B3 DST FAM120A LMO7 EIF2B1 RPUSD3 GEMIN4 SCRIB	4.59e-04	949	120	11	36574265
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CCDC185 ARMC3 UTP14A DNAH2 DBN1 EPX C2orf78 PHEX ARRB1 SF3B3 DST LMO7 ATM BSN	4.62e-04	1442	120	14	35575683
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	NES NVL DBN1 MYOF DST SERPINC1 USP39 SCRIB PCM1	4.88e-04	660	120	9	32780723
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	VWA8 FASTKD2 SF3B3 DST LMO7 KDM7A BSN CNOT1	5.16e-04	529	120	8	14621295
Pubmed	Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome.	SLC27A6 ACSM4	5.22e-04	10	120	2	17762044
Pubmed	Establishment of a molecular genetic map of distal mouse chromosome 1: further definition of a conserved linkage group syntenic with human chromosome 1q.	LAMC1 SERPINC1	5.22e-04	10	120	2	3384439
Pubmed	Cortical migration defects in mice expressing A-RAF from the B-RAF locus.	NES ARAF	5.22e-04	10	120	2	16980614
Pubmed	Angiogenic sprouting into neural tissue requires Gpr124, an orphan G protein-coupled receptor.	NES FLT4	5.22e-04	10	120	2	21282641
Pubmed	Osterix regulates tooth root formation in a site-specific manner.	NES PHEX	5.22e-04	10	120	2	25568170
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	UTP14A NVL DST TAF9B CCDC87 USP39 SCRIB	5.71e-04	410	120	7	26949251
Pubmed	Four loci from human chromosome 1 are physically assigned to sheep chromosome 1p.	LAMC1 SERPINC1	6.36e-04	11	120	2	8589528
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	NES DBN1 NPM3 SF3B3 DST FAM120A LMO7 P4HA1 WASF2 GEMIN4 USP39 CNOT1	6.36e-04	1149	120	12	35446349
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	VWA8 LAMC1 SF3B3 SCRIB CNOT1	6.98e-04	202	120	5	24639526
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	NVL DBN1 NPM3 SF3B3 FAM120A LMO7 CBFA2T2 GEMIN4 USP39 FAR1	7.27e-04	847	120	10	35850772
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	DLGAP2 NPM3 CBFA2T2 CCDC87 ATM BSN ZMYM5	7.55e-04	430	120	7	35044719
Pubmed	A comparative gene map of the horse (Equus caballus).	LAMC1 SERPINC1	7.62e-04	12	120	2	10613847
Pubmed	Comparative analysis of type II classic cadherin mRNA distribution patterns in the developing and adult mouse somatosensory cortex and hippocampus suggests significant functional redundancy.	CDH24 CDH18	7.62e-04	12	120	2	22102170
Pubmed	Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality.	VWA8 FASTKD5 FASTKD2 ACAD10 ECSIT	7.79e-04	207	120	5	31056398
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	CACNA2D1 VPS11 LAMC1 GEMIN4 ATM SCRIB	7.84e-04	313	120	6	38270169
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	RNF213 SCRIB FAR1 BSN CNOT1	7.96e-04	208	120	5	33230847
Pubmed	Maturation of the olfactory sensory neurons by Apaf-1/caspase-9-mediated caspase activity.	SEMA7A BSN	8.98e-04	13	120	2	20624980
Pubmed	A Genome-wide CRISPR Death Screen Identifies Genes Essential for Oxidative Phosphorylation.	FASTKD2 RPUSD3	8.98e-04	13	120	2	27667664
Pubmed	O-GlcNAcylated LARP1 positively regulated by circCLNS1A facilitates hepatoblastoma progression through DKK4/β-catenin signalling.	SF3B3 CNOT1	8.98e-04	13	120	2	37070251
Pubmed	Fukutin-related protein alters the deposition of laminin in the eye and brain.	NES LAMC1	8.98e-04	13	120	2	21900571
Pubmed	Interactome and Ubiquitinome Analyses Identify Functional Targets of Herpes Simplex Virus 1 Infected Cell Protein 0.	DBN1 SF3B3 LMO7 P4HA1	9.19e-04	124	120	4	35516420
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	VWA8 TUT7 LAMC1 RSU1 NPM3 FAM120A LMO7 P4HA1 EIF2B1 RPUSD3 GEMIN4 CNOT1 PCM1	9.22e-04	1371	120	13	36244648
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	DBN1 RSU1 ARAF DST LMO7 CNOT1 PCM1	9.34e-04	446	120	7	24255178
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	GDPD1 VMA21 BMP2K LAMC1 FASTKD5 FASTKD2 ALG9 PXMP2 GEMIN4 FAR1 CNOT1 SOAT1	9.47e-04	1203	120	12	29180619
Pubmed	Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.	VWA8 LAMC1 DBN1 SF3B3 EXOC2	1.00e-03	219	120	5	31353912
Pubmed	Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.	MYOF DST FAM120A LMO7 SCRIB FAR1	1.01e-03	329	120	6	34316702
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	DLGAP2 SEMA7A PCDHA11 EPX SERPINC1 TSKS	1.01e-03	329	120	6	17474147
Pubmed	Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.	PCDHB10 PCDHA11 PCDHB1	1.02e-03	57	120	3	32633719
Pubmed	Basement membrane attachment is dispensable for radial glial cell fate and for proliferation, but affects positioning of neuronal subtypes.	NES LAMC1	1.05e-03	14	120	2	16873583
Pubmed	Quantitative Trait Locus Mapping of Macrophage Cholesterol Metabolism and CRISPR/Cas9 Editing Implicate an ACAT1 Truncation as a Causal Modifier Variant.	CCDC185 SOAT1	1.05e-03	14	120	2	29097366
Pubmed	Rac1 signaling is critical to cardiomyocyte polarity and embryonic heart development.	WASF2 SCRIB	1.05e-03	14	120	2	25315346
Pubmed	CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.	PCDHB10 PCDHA11 PCDHB1	1.08e-03	58	120	3	30377227
Pubmed	Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction.	DLGAP2 LAMC1 DBN1 BSN	1.13e-03	131	120	4	28634551
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	DMXL2 MYOF DST LMO7 SCRIB	1.13e-03	225	120	5	12168954
Pubmed	Dephosphorylation of the transcriptional cofactor NACA by the PP1A phosphatase enhances cJUN transcriptional activity and osteoblast differentiation.	NES LMO7	1.20e-03	15	120	2	30948508
Pubmed	Differential Spatiotemporal Expression of Type I and Type II Cadherins Associated With the Segmentation of the Central Nervous System and Formation of Brain Nuclei in the Developing Mouse.	CDH24 CDH18	1.20e-03	15	120	2	33833667
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	CACNA2D1 SEMA7A NVL ACAD10 FAM120A USP39 PCM1	1.34e-03	475	120	7	31040226
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	NES DLGAP2 CACNA2D1 DMXL2 DBN1 SF3B3 DST FAM120A LMO7 SCRIB BSN CNOT1 PCM1	1.36e-03	1431	120	13	37142655
Pubmed	Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling.	P4HA1 CPNE3 GEMIN4 MARCHF4 SOAT1	1.37e-03	235	120	5	32614325
Pubmed	Rab40-Cullin5 complex regulates EPLIN and actin cytoskeleton dynamics during cell migration.	DST LMO7	1.37e-03	16	120	2	33999101
Pubmed	Early loss of Scribble affects cortical development, interhemispheric connectivity and psychomotor activity.	NES SCRIB	1.37e-03	16	120	2	33907211
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	TUT7 UTP14A DBN1 MYOF SF3B3 DST FAM120A LMO7 CPNE3 GEMIN4 USP39 SCRIB	1.38e-03	1257	120	12	36526897
Pubmed	Laminin α1 is essential for mouse cerebellar development.	NES LAMC1	1.55e-03	17	120	2	21983115
Pubmed	Guanine Nucleotide-Binding Protein-Like 1 (GNL1) binds RNA G-quadruplex structures in genes associated with Parkinson's disease.	SF3B3 FAM120A	1.55e-03	17	120	2	33305682
Pubmed	An NAD+-Dependent Deacetylase SIRT7 Promotes HCC Development Through Deacetylation of USP39.	WASF2 USP39	1.55e-03	17	120	2	32711345
Pubmed	Polymorphisms revealed by PCR with single, short-sized, arbitrary primers are reliable markers for mouse and rat gene mapping.	LAMC1 SERPINC1	1.55e-03	17	120	2	1617216
Pubmed	Mouse models of male infertility.	UTP14A ATM	1.55e-03	17	120	2	12360237
Interaction	HCST interactions	PI4K2B DMXL2 RTTN RNF213 ACAD10 GEMIN4 PRMT9 ATM ITPRIPL1	3.13e-06	205	117	9	int:HCST
Interaction	NPTN interactions	DMXL2 VMA21 RNF213 FASTKD5 ACAD10 P4HA1 GEMIN4 ZFYVE26 ATM EXOC2	5.17e-06	278	117	10	int:NPTN
Interaction	MRPS17 interactions	VWA8 NEIL1 FASTKD5 FASTKD2 ACAD10 ECSIT NPM3 FAM120A RPUSD3	7.70e-06	229	117	9	int:MRPS17
Interaction	H2AP interactions	GDPD1 VPS11 DGKH AP1G2 ZFYVE26 ATM	8.23e-06	82	117	6	int:H2AP
Interaction	NPY2R interactions	DMXL2 FLT4 FASTKD5 ACAD10 ATM	4.08e-05	66	117	5	int:NPY2R
GeneFamily	Dolichyl D-mannosyl phosphate dependent mannosyltransferases\|Phosphatidylinositol glycan anchor biosynthesis	PIGV ALG9	6.00e-04	9	75	2	430
ToppCell	facs-Lung-EPCAM-18m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHB10 ACAD10 PKD1L3 TAF9B SECISBP2 PRMT9 CNOT1	4.04e-07	170	120	7	12203d4410f38cc933d9f160b5fb76828df94119
ToppCell	facs-Lung-EPCAM-18m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHB10 ACAD10 PKD1L3 TAF9B SECISBP2 PRMT9 CNOT1	4.04e-07	170	120	7	f9decb3bf3bf6d4996b0ac27af768236e116aac5
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasmablast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IL12RB2 ARMC3 SEMA7A JMJD4 ARL9 WDFY4 ITPRIPL1	1.01e-06	195	120	7	a045fb8a377e54fb57fef1181d4c3fc15d627ef6
ToppCell	droplet-Liver-nan-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UTS2B SLC27A6 PLPP7 RASGRP1 MYOF ARHGAP19	7.29e-06	172	120	6	f814b6134ad608015765399d54cc1e5e1873ed34
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	DLGAP2 CACNA2D1 TMEM63C BSN MARCHF4 CDH18	1.01e-05	182	120	6	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	LPS_IL1RA_TNF\|World / Treatment groups by lineage, cell group, cell type	LAMC1 ACAD10 PHEX IGSF10 MYOF LMO7	1.58e-05	197	120	6	0a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PHEX IGSF10 MYOF DST CBFA2T2 BSN	1.58e-05	197	120	6	fdb92985f7df0c280b87d3e43c2394e70786a2c7
Disease	ocular hypertension, response to triamcinolone acetonide	GDPD1 VWA8 TUT7 RPUSD3	3.78e-05	49	113	4	EFO_0006954, EFO_1001069
Disease	rectum cancer	DLGAP2 LAMC1 WDFY4	5.63e-04	42	113	3	EFO_1000657
Disease	vascular endothelial growth factor measurement	VWA8 DNAH2 DGKH	1.31e-03	56	113	3	EFO_0004762
Disease	melanoma	DLGAP2 CBFA2T2 ATM EXOC2	1.43e-03	126	113	4	EFO_0000756
Disease	serum non-albumin protein measurement	UGT3A1 DNAH2 NPM3 RASGRP1 EXOC2 TSKS	2.71e-03	361	113	6	EFO_0004568
Disease	otitis media (implicated_via_orthology)	IDUA PHEX	3.19e-03	22	113	2	DOID:10754 (implicated_via_orthology)
Disease	Immunologic Deficiency Syndromes	RASGRP1 ATM	3.49e-03	23	113	2	C0021051
Disease	cancer (implicated_via_orthology)	FLT4 ARAF DST ATM SCRIB	3.77e-03	268	113	5	DOID:162 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
PNFQEFQKLPQASRR	CCDC185	581	Q8N715
APFINQFQVPIRVFL	PRMT9	726	Q6P2P2
RSLPKPQNQFLIQDF	C2orf78	836	A6NCI8
FRSLPANQQKLLPQF	CARNMT1	91	Q8N4J0
QLQFIPSEFRGQLPK	ALG9	486	Q9H6U8
PTPQLRAEVFIKFIQ	RASGRP1	266	O95267
ITQLFRILNPNKAPL	AP1G2	741	O75843
NPVLPLVVFANKQDL	ARL9	116	Q6T311
PFRQFQNAPKEALAQ	CPNE3	491	O75131
LPNQKSFLPLDRKQF	ACAD10	161	Q6JQN1
TGFLKLNEFPIRQPF	B3GALT5	181	Q9Y2C3
RIPANLLDQFEKQLP	DLGAP2	186	Q9P1A6
INRCNRPLPKNFNFA	ACSM4	41	P0C7M7
RPLPKNFNFAADVLD	ACSM4	46	P0C7M7
FQCRAKLQELNAIPP	ARMC3	181	Q5W041
TLKTRVLPNAFNIPN	DMXL2	3016	Q8TDJ6
SLNPNRVTFKANRPF	SERPINC1	426	P01008
FLRQEKQPQIINPEL	CCDC87	531	Q9NVE4
VPFFAVRAQQPQQEK	BMP2K	861	Q9NSY1
RNLFRKLISFQPPQL	C5orf64	11	Q2M2E5
DPKQPLQARFRALFT	DOHH	16	Q9BU89
RKDLFVANVQSFPPA	ARRB1	76	P49407
AILAPVRNPDQFKAL	NVL	596	O15381
INDNAPVFLNKEPLL	PCDHB1	126	Q9Y5F3
QQLANEFPFPVNIIL	PM20D1	296	Q6GTS8
INDNPPVFSLREQKL	PCDHA11	126	Q9Y5I1
KIAIRDINDNAPQFP	PCDH20	196	Q8N6Y1
NPNRPKVLNVISLEF	KDM7A	216	Q6ZMT4
FKRNPLEQAFRRPNV	FAR1	326	Q8WVX9
AQPQQEPLALVFRFG	NEIL1	66	Q96FI4
LDDFQLQPPVTFRLK	NPM3	111	O75607
RDSFKLINSQFPFPQ	DST	2871	Q03001
FQQKVFVLLAALRPQ	IL12RB2	646	Q99665
LEEQKQRQKAPFPAA	BSN	2466	Q9UPA5
FIIKVQDINDNPPIF	CDH24	136	Q86UP0
RPIEKLQNPIVTQFF	TMEM63C	441	Q9P1W3
PQPEFQQLLRKAKLF	MGAT5B	516	Q3V5L5
VRLFPLNQQDVPDKF	EIF2B1	236	Q14232
NPNRVFFLNVPFDSI	AK8	371	Q96MA6
KLQEATNFPLRPFVI	CBFA2T2	161	O43439
KRQLSENRKPFNFLP	PCM1	131	Q15154
KFLFNLPLNIERNIQ	EXOC2	281	Q96KP1
PEAFNTPFLNIDKLR	KRTDAP	41	P60985
NDPRIKNQRDCIPFF	EPX	271	P11678
TPVPAFLKNQEFLQA	NES	366	P48681
PIFNILKEKNFQPRI	L1RE1	266	Q9UN81
TALPFNRFLPNKSRQ	LMO7	306	Q8WWI1
NRIPLLKEVFEAFPN	GDPD1	131	Q8N9F7
PVQFNFNKIRPGEVL	GDPGP1	121	Q6ZNW5
RNNEVTLFKGIFPPL	FMO6P	346	O60774
AIIAQRPDNPREFFK	DBN1	281	Q16643
EVAKQLDLNPNRFPI	FAM120A	221	Q9NZB2
QENLPFLLKPSVENF	PCDHB10	386	Q9UN67
RRFKQLLNPAQVFDL	DGKH	351	Q86XP1
EQLKQLQRFDPSAVP	NSUN6	416	Q8TEA1
NRNPKFILAPAKQED	P4HA1	316	P13674
DPLPENIRKQFQSQF	PI4K2B	276	Q8TCG2
IPKTFRNAEPVNLFQ	ITPRIPL1	506	Q6GPH6
LIPRHQELFNKNPVF	CDKL2	221	Q92772
IQQAIDPKNLSRLFP	ATM	3036	Q13315
KFQREERPLFPQILA	ARAF	551	P10398
EVQLDVNLKPLPFNR	FASTKD5	591	Q7L8L6
RPTFRNPFNEKIVAQ	IGSF10	2336	Q6WRI0
PFFQKPVALANLRGN	CARD6	521	Q9BX69
LNFNEFIDRKTPNNP	CACNA2D1	681	P54289
AFSPQPKELLQQLRE	JMJD4	441	Q9H9V9
KNPKVFDPLRFSQEN	CYP4X1	421	Q8N118
RVFDESLNFQKIPPL	CEP170P1	66	Q96L14
QQIRQLFPKFADTPI	IDUA	281	P35475
FNDLKVFLLRRPPQA	MARCHF4	46	Q9P2E8
FLDERLPVNPNFTLK	CDH18	526	Q13634
RPALTPFEFQKLLNN	LAMC1	636	P11047
PLFNAIVQDLFPNIE	DNAH2	2021	Q9P225
NFNIVREFPLNPKAL	DNAH2	2111	Q9P225
PENRLPSLKNEFNLV	SLC22A13	116	Q9Y226
PIAIFLQENRSNFPV	PPP4R1L	111	Q9P1A2
QLLNIFPKEVFRPRN	ECSIT	131	Q9BQ95
SNPQLQKPLFAIFLI	OR1L6	56	Q8NGR2
PPNIAELKNLEVLNF	RSU1	56	Q15404
FLLPAENNKPQRQVL	RPUSD3	276	Q6P087
QDFPAEIFLQRPKIV	RTTN	216	Q86VV8
FLLDIARQKNQTPLP	TAF9B	91	Q9HBM6
FQRPFNTDLALPNKL	UTS2B	61	Q765I0
APLFRNIKQEPFSAR	SOAT1	346	P35610
NFQAKDQALFPRLPS	TEX55	431	Q96M34
PQVPLFNILAKFNGI	USP39	411	Q53GS9
LRLANNQLQFLPPEV	LRRC28	116	Q86X40
FPLAPFNQLLQKDII	FASTKD2	511	Q9NYY8
LLRIPFQNNNSLGFK	PKD1L3	336	Q7Z443
LFLPRNQIGFVPEKT	RXFP2	286	Q8WXD0
QNIPFVFALNRKALG	SECISBP2	721	Q96T21
NQLRELPKPFFRLLN	SCRIB	46	Q14160
EKAAQVYRLPFPIQN	SLC23A3	541	Q6PIS1
PPENIQEKIAFIFNN	CNOT1	1091	A5YKK6
ELKQVPNFLLAAPVA	PIGV	321	Q9NUD9
LQRVPFNVDFDKLPR	RNF213	2356	Q63HN8
VSNLNRQFLFRPKDI	UBA3	106	Q8TBC4
IKPVPQDLDNFIANF	UGT3A1	276	Q6NUS8
PLQNQPARAFSAVKV	SUN5	326	Q8TC36
EEFIPIFANNPRELK	VPS11	591	Q9H270
PLQFININYVPLKFR	PXMP2	161	Q9NR77
EQPFINKPDTLLVNR	FLT4	136	P35916
QAQLIPKLIFLFNEP	WDFY4	1506	Q6ZS81
NQIRFPAGELQKPFF	PHEX	546	P78562
TNKNFNRLQDVFLLP	SEMA7A	296	O75326
PLKPILEEFGRQFQN	TSKS	416	Q9UJT2
PVVLKNRQAEQLVFP	UTP14A	146	Q9BVJ6
QPIIFNPDFFVEKLR	ARHGAP19	36	Q14CB8
FFQPRPLKNLVLVDE	SF3B3	386	Q15393
ILELSPQPKNFNRTA	PRR33	311	A8MZF0
QDQKLFDRNSLPVPV	WASF2	106	Q9Y6W5
FRNLLLVAHQPFKPD	ZNF112	41	Q9UJU3
SLSPVALLRKQNFQP	ZMYM5	216	Q9UJ78
KAALNALQPPEFRNE	VMA21	6	Q3ZAQ7
PDLQIKITNIFRPGF	TEX15	771	Q9BXT5
PGLLISRVNAKNPFF	SLC27A6	421	Q9Y2P4
AIFFLQQRKEPLLPV	TUT7	466	Q5VYS8
PAKFAQILTRDPQVN	VWA8	1841	A3KMH1
AKNQPPILNRLAKIF	TTC22	291	Q5TAA0
FSRCLKPPFDLNQLN	ZFYVE26	2086	Q68DK2
SPNDFKPQDFLRLQQ	XYLT2	481	Q9H1B5
VLNRAEFLSLNQPPK	PLPP7	16	Q8NBV4
FVPLLNLKPFAQELQ	GEMIN4	896	P57678
LLQNVARFKGFPQPI	MYOF	1676	Q9NZM1