Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionoxidoreductase activity, acting on metal ions, oxygen as acceptor

CP HEPHL1

6.76e-056432GO:0016724
GeneOntologyMolecularFunctionferroxidase activity

CP HEPHL1

6.76e-056432GO:0004322
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

SCN10A KCNJ6

6.04e-0417432GO:0099508
GeneOntologyMolecularFunctionoxidoreductase activity, acting on metal ions

CP HEPHL1

6.78e-0418432GO:0016722
DomainMULTICOPPER_OXIDASE2

CP HEPHL1

1.48e-053422PS00080
DomainCu-oxidase_2

CP HEPHL1

2.95e-054422IPR011706
DomainCu-oxidase_2

CP HEPHL1

2.95e-054422PF07731
DomainCu-oxidase_3

CP HEPHL1

4.92e-055422IPR011707
DomainCu_oxidase_CS

CP HEPHL1

4.92e-055422IPR033138
DomainMULTICOPPER_OXIDASE1

CP HEPHL1

4.92e-055422PS00079
DomainCu-oxidase_3

CP HEPHL1

4.92e-055422PF07732
DomainCu_oxidase_Cu_BS

CP HEPHL1

7.36e-056422IPR002355
DomainZnf_FYVE_PHD

ZFYVE26 PLEKHF2 PHF24 KDM4B

3.27e-04147424IPR011011
Domain-

CP HEPHL1

4.42e-04144222.60.40.420
DomainCupredoxin

CP HEPHL1

1.11e-0322422IPR008972
DomainEGF_3

ADAM19 VWCE TENM3 NCAN

1.88e-03235424PS50026
DomainFYVE

ZFYVE26 PLEKHF2

1.93e-0329422PF01363
DomainFYVE

ZFYVE26 PLEKHF2

1.93e-0329422SM00064
DomainEGF-like_dom

ADAM19 VWCE TENM3 NCAN

2.32e-03249424IPR000742
DomainEGF_1

ADAM19 VWCE TENM3 NCAN

2.53e-03255424PS00022
DomainZnf_FYVE-rel

ZFYVE26 PLEKHF2

2.65e-0334422IPR017455
DomainEGF-like_CS

ADAM19 VWCE TENM3 NCAN

2.75e-03261424IPR013032
DomainEGF_2

ADAM19 VWCE TENM3 NCAN

2.90e-03265424PS01186
DomainZnf_FYVE

ZFYVE26 PLEKHF2

3.30e-0338422IPR000306
DomainZF_FYVE

ZFYVE26 PLEKHF2

3.65e-0340422PS50178
DomainSushi

CSMD2 NCAN

6.10e-0352422PF00084
Domain-

CSMD2 ZZEF1

6.10e-03524222.60.120.290
DomainCCP

CSMD2 NCAN

6.56e-0354422SM00032
DomainSUSHI

CSMD2 NCAN

7.04e-0356422PS50923
DomainSushi_SCR_CCP_dom

CSMD2 NCAN

7.29e-0357422IPR000436
DomainCUB_dom

CSMD2 ZZEF1

7.29e-0357422IPR000859
DomainEGF_extracell

ADAM19 TENM3

8.05e-0360422IPR013111
DomainEGF_2

ADAM19 TENM3

8.05e-0360422PF07974
Pubmed

The Placental Ferroxidase Zyklopen Is Not Essential for Iron Transport to the Fetus in Mice.

CP HEPHL1

1.56e-06244234114013
Pubmed

Interaction of hematopoietic progenitor kinase 1 and c-Abl tyrosine kinase in response to genotoxic stress.

ABL1 MAP4K1

1.56e-06244211278340
Pubmed

Identification of zyklopen, a new member of the vertebrate multicopper ferroxidase family, and characterization in rodents and human cells.

CP HEPHL1

1.56e-06244220685892
Pubmed

The chemokine interleukin-8 and the surface activation protein CD69 are markers for Bcr-Abl activity in chronic myeloid leukemia.

CD69 ABL1

4.69e-06344219383348
Pubmed

[Ceruloplasmin, hephaestin and zyklopen: the three multicopper oxidases important for human iron metabolism].

CP HEPHL1

4.69e-06344224988611
Pubmed

Sensory neuron-derived TAFA4 promotes macrophage tissue repair functions.

SCN10A PHF24

9.37e-06444234012116
Pubmed

Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).

ABL1 CSMD2 TENM3

1.55e-053844322952603
Pubmed

ABL kinases regulate the stabilization of HIF-1α and MYC through CPSF1.

CPSF1 ABL1

2.34e-05644237040401
Pubmed

SH2/SH3 adaptor proteins can link tyrosine kinases to a Ste20-related protein kinase, HPK1.

ABL1 MAP4K1

4.36e-0584429346925
Pubmed

Genetic mapping of the peripheral sodium channel genes, Scn9a and Scn10a, in the mouse.

SCN10A ABL1

5.60e-0594428854872
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

SCN10A ARHGEF18 TEX14 AFF2 MAP4K1

2.06e-0443044535044719
Pubmed

Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain.

ARHGEF18 FARP2

2.36e-041844212799088
Pubmed

Identification of Modifier Genes in a Mouse Model of Gaucher Disease.

AFF2 PLEKHF2

3.56e-042244227568557
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

CPSF1 CEP76 HAO2 SPEG KDM4B

4.01e-0449744536774506
Pubmed

Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies.

CSMD2 UNC5B

5.79e-042844218839057
Pubmed

SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome.

ABL1 MAP4K1

7.57e-043244222974441
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

ABL1 AFF2 CSMD2 MAP4K1

7.92e-0432944417474147
Pubmed

Identification and applications of repetitive probes for gene mapping in the mouse.

ABL1 ODC1

1.07e-03384421673105
Pubmed

Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent.

SYCP2 TEX14

1.18e-034044220378615
Pubmed

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.

TMEM219 TENM3 KDM4B FARP2

1.24e-0337144415747579
Cytoband9q21.13

NMRK1 GDA

2.66e-04254429q21.13
Cytoband4q35.1

CENPU TENM3

5.54e-04364424q35.1
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

ZFYVE26 PLEKHF2

7.04e-043123281
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF18 PLEKHF2 FARP2

2.18e-03206233682
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CSMD2 NCAN

2.37e-03572321179
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF18 FARP2

3.16e-0366232722
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

UNC5B SPEG

1.76e-02161232593
CoexpressionGSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_UP

CD69 ARHGEF18 ADAM19 ODC1 PLEKHF2

1.58e-05193435M4961
CoexpressionGSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_UP

CD69 ARHGEF18 ADAM19 ODC1 MAP4K1

1.70e-05196435M4954
CoexpressionHAHTOLA_MYCOSIS_FUNGOIDES_CD4_DN

NMRK1 CD69 ARHGEF18 MAP4K1

3.80e-05115434M19849
CoexpressionFOSTER_TOLERANT_MACROPHAGE_DN

CD69 CP GDA ODC1 TMEM219 PLEKHF2

5.87e-05418436M12676
CoexpressionFOSTER_TOLERANT_MACROPHAGE_DN

CD69 CP GDA ODC1 TMEM219 PLEKHF2

7.32e-05435436MM1221
ToppCellHealthy-CD4+_T_activated|World / disease group, cell group and cell class

CD69 CP SYCP2 TEX14 VWCE CPT1C

5.22e-09140446407691970ec72a3afb45e431cf48814546b8acff
ToppCellHealthy-CD4+_T_activated|Healthy / disease group, cell group and cell class

CP SYCP2 TEX14 VWCE CPT1C

3.18e-0714544545e8089fdf7d6f69b383816d8945e39fba24c873
ToppCellwk_20-22-Hematologic_Lymphocytic-B-CD5-_Mature_B|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CD69 ADAM19 MAP4K1 PLEKHF2 KDM4B

1.38e-06195445fe3f978820a63c26a537d97e69f7999dd60bb0ea
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

VWCE TENM3 SPEG PHF24

6.63e-0612344487401764a073c1808f214642a9c84299c78f7ec7
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFYVE26 GDA SYCP2 ADAM19

1.45e-051504446e806a028c0519489151c181d9907e05289e27e0
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_B-B_cells-B-cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD69 ARHGEF18 ADAM19 MAP4K1

2.27e-05168444eeb381b62c7ba263af96de1194ed59e57b6ca3ae
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_B-B_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD69 ARHGEF18 ADAM19 MAP4K1

2.27e-05168444063d0368d656962b335154c230bdcd9236e7c9ad
ToppCell367C-Lymphocytic-B_cell|367C / Donor, Lineage, Cell class and subclass (all cells)

CD69 ODC1 PLEKHF2 KDM4B

2.27e-051684441943ae24ff90218b8c2c10b4102b5007ae35fc85
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_B|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD69 ARHGEF18 ADAM19 MAP4K1

2.27e-05168444a7c4251d8a83bc30196a444028a35c17c24dc291
ToppCell367C-Lymphocytic-B_cell-|367C / Donor, Lineage, Cell class and subclass (all cells)

CD69 ODC1 PLEKHF2 KDM4B

2.27e-05168444f4414d462d35abd00e3c1446302d7060f8a48d48
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SPSB4 MELTF RDH13 TENM3

2.32e-0516944458e22f9119240664515fe91ca53812611a8f17d6
ToppCellLPS-IL1RA-Lymphocytic_B-B_cells-B-cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD69 ARHGEF18 ADAM19 MAP4K1

2.37e-0517044492e0873f618b2fa60c4d555b10f234d5cbcf3325
ToppCellLPS-IL1RA-Lymphocytic_B-B_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD69 ARHGEF18 ADAM19 MAP4K1

2.37e-05170444c181991f933b779f99afc3782f292306f209e2ac
ToppCellLPS-IL1RA-Lymphocytic_B|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD69 ARHGEF18 ADAM19 MAP4K1

2.37e-0517044456284fbfd1e53f67c8c0b7fba64505a4002adba2
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARHGEF18 CEP76 CSMD2 KIAA1614

2.43e-05171444ea60d9e9df28ab991fbdb596784b44f6a9fc5827
ToppCellLPS-antiTNF-Lymphocytic_B|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD69 ARHGEF18 ADAM19 MAP4K1

2.60e-05174444cc493654ea3517bc6a145c7f787f304929636f86
ToppCellLPS-antiTNF-Lymphocytic_B-B_cells-B-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD69 ARHGEF18 ADAM19 MAP4K1

2.60e-051744449eb3504f9340517ef5d056503044fbdb9ffeb714
ToppCellLPS-antiTNF-Lymphocytic_B-B_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD69 ARHGEF18 ADAM19 MAP4K1

2.60e-05174444b4c2d1c029fcd0d4926aa79a5b789c713919dcf3
ToppCellLPS_only-Lymphocytic_B-B_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD69 ARHGEF18 ADAM19 MAP4K1

2.78e-05177444c82332c5f656aa26513e4f7525d5d4d733019725
ToppCellLPS_only-Lymphocytic_B|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD69 ARHGEF18 ADAM19 MAP4K1

2.78e-051774445ed65e08d773d157840317c72e0d43c261d438d4
ToppCellLPS_only-Lymphocytic_B-B_cells-B-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD69 ARHGEF18 ADAM19 MAP4K1

2.78e-051774448a955a7ab84c434f9ad4b467246b8be3cb479406
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D231|Adult / Lineage, Cell type, age group and donor

SPSB4 ADAM19 TENM3 PHF24

2.84e-05178444c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCellIPF-Lymphoid-B|World / Disease state, Lineage and Cell class

CD69 ARHGEF18 ADAM19 MAP4K1

2.97e-0518044430f9398c9b784f49470847a025bac90687e997a1
ToppCellIPF-Lymphoid-B|IPF / Disease state, Lineage and Cell class

CD69 ARHGEF18 ADAM19 MAP4K1

3.17e-05183444e37d2c015c34471a8a54a0299e94b0371e1ada5a
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MELTF ABL1 CSMD2 VWCE

3.30e-051854449faa35ceb89ccd2979072286f063687c9f846ce3
ToppCellwk_20-22-Hematologic_Lymphocytic-B-CD5+_CCL22-_mature_B|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CD69 MAP4K1 PLEKHF2 KDM4B

3.37e-051864443941d4af5f2b209d71f59d7d920f2322131b4a0c
ToppCellhealthy_donor-Lymphocytic-B_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

CD69 ADAM19 ODC1 PLEKHF2

3.82e-051924447d9e5772b6e531b50ed4e4d6304ef11235f27f37
ToppCellControl-Lymphoid-T|World / Disease state, Lineage and Cell class

CD69 TCAF2 ADAM19 MAP4K1

3.82e-05192444253cf4d2cf88ad8c45b73779336180840bef054b
ToppCellhealthy_donor-Lymphocytic-B_cell-|healthy_donor / Disease condition, Lineage, Cell class and subclass

CD69 ADAM19 ODC1 PLEKHF2

3.82e-05192444975312f9d6cede4d4f5b737e481e5c73accc8c50
ToppCellControl-Lymphoid-T|Control / Disease state, Lineage and Cell class

CD69 TCAF2 ADAM19 MAP4K1

3.90e-05193444af928046ccd1ca874be1534aef6ca7f27d90bc46
ToppCellwk_20-22-Hematologic_Lymphocytic-B-Immature_B|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CD69 MAP4K1 PLEKHF2 KDM4B

3.98e-05194444f957cec2f309d726e095d18a7da32789dca92a36
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CENPU CP GDA

2.15e-041184438d96a4879b28979fa04fbaeffa271a6b9ecbe867
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature|E16.5-samps / Age Group, Lineage, Cell class and subclass

SPSB4 AFF2 FARP2

2.80e-041294435e4783cc63afdeaebdfaecb72f95f3efc8d3c4a3
ToppCellLPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-T-cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SCN10A CD69 HEPHL1

3.48e-04139443ecc2a6ecc27748c50885cd4f0ad8a8cd1252aee6
ToppCellE18.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD69 GDA SYCP2

3.94e-0414544388e463d5396a8fea2b7b1ecf3c9b144e16b35234
ToppCellE18.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD69 GDA SYCP2

3.94e-04145443911fee7f27694393e348d94470a1a4e890038902
ToppCellPND01-Immune-Immune_Myeloid-Granulocytic|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD69 GDA SYCP2

4.18e-0414844374f1f9d1a53dc1a09cb6a504cbbdc7496c5b6879
ToppCellE18.5-Immune-Immune_Myeloid-Granulocytic|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD69 ARHGEF18 GDA

4.27e-041494435a5e9660f7d9b527f50a92d94d4c0c8aedb82c0b
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Cerebellum / BrainAtlas - Mouse McCarroll V32

TEX14 AFF2 PHF24

4.27e-041494436e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 ABCA10 CPT1C

4.35e-041504431270f33f9d7e46e55adf1a96e8beee858b95589d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 ABCA10 CPT1C

4.35e-04150443156118ce1d69522624196410cba18b8354cd0bb4
ToppCellMS-CD4-CD8_1|MS / Condition, Cell_class and T cell subcluster

GDA ABL1 CSMD2

4.35e-041504437dc95c58b98d8c4c6c49fb1a03ec6ac24fb41f54
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CPT1C UNC5B NCAN

4.44e-041514433b4c57bad61e17a573e6f8dc6b917fba5fd56c43
ToppCellfacs-Heart-LV-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD69 SYCP2 CEP76

4.44e-041514435893a51585a65f1902cf85124a5ed9f02b4eb82a
ToppCellfacs-Heart-LV-18m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD69 SYCP2 CEP76

4.44e-04151443771224e0d6fccfa4225b3adccd7bc22a89a40793
ToppCellChildren_(3_yrs)-Immune-mast_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CD69 MELTF AFF2

4.44e-04151443bbf735c6433c3fc2feedb24ed6f48c51d545fb60
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CENPU CP MAP4K1

4.61e-04153443991782d111d66e25b40319d4e6dea40f2c2c0805
ToppCellClub_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

CP MELTF KIAA1614

4.61e-0415344377030b0e033f3635b1bbe7552a28c074ea7bb106
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYCP2 AFF2 FARP2

4.79e-04155443441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADAM19 TEX14 MAP4K1

4.79e-041554439f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCellfacs-Trachea-24m-Hematologic-myeloid-granulocyte-granulocyte_l26|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD69 HAO2 UNC5B

4.88e-04156443da5cfa8fa9595613f04ce9511f8b42bad34d995a
ToppCell5'-Adult-Appendix-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CENPU AFF2 MAP4K1

4.88e-04156443203ef22eb76bd2b829b027c30af0557080f4006c
ToppCellfacs-Spleen-nan-3m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDA SYCP2 AFF2

4.88e-04156443f532ef4e92ac7661b1a8a4f2e98d80ce8d4e3655
ToppCellfacs-Spleen-nan-3m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDA SYCP2 AFF2

4.88e-04156443da4f35353a84d919e683554932f110e29568df33
ToppCellfacs-Spleen-nan-3m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDA SYCP2 AFF2

4.88e-04156443f1e25ff85c5f2f8555f9fb5ae5daed7ddb418fd1
ToppCell368C-Fibroblasts-Fibroblast-F|368C / Donor, Lineage, Cell class and subclass (all cells)

ABL1 EFCAB7 KIAA1614

4.97e-0415744374038192f016f95f80e0189035ee8ccc22ceb1b8
ToppCell368C-Fibroblasts-Fibroblast-F-|368C / Donor, Lineage, Cell class and subclass (all cells)

ABL1 EFCAB7 KIAA1614

4.97e-04157443982e6ea78c7dabdb7c07c4a5fb2425d5e45b5b94
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD69 ADAM19 TEX14

5.06e-04158443b1b1e50ddd231dcd10cc8e6bb68b2a5e0bb1450a
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF18 TEX14 HAO2

5.16e-041594434000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCelldroplet-Liver-LIVER_NPC-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD69 ARHGEF18 MAP4K1

5.16e-04159443997963d879e5819683793cddf5e1acff1b81a1b8
ToppCelldroplet-Lung-nan-21m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDA SYCP2 ADAM19

5.16e-04159443555ebf719504980c7584203a3ee1ba5779ab76d8
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF18 TEX14 HAO2

5.16e-041594437619d0d49738dd08daf01b42664691a5323aa793
ToppCellCOVID-CD4-CD4_Treg|COVID / Condition, Cell_class and T cell subcluster

CENPU SYCP2 ADAM19

5.16e-04159443037cd97c41eb2f91fd3f69bbb3ffdfd6c0158410
ToppCelldroplet-Liver-LIVER_NPC|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD69 ARHGEF18 MAP4K1

5.16e-04159443e4eaa88772835d6b78e1a18a0cec52de51e80339
ToppCelldroplet-Lung-nan-21m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDA SYCP2 ADAM19

5.16e-04159443a6a5cded6da02a112e04c2c71ce08cc27c1c5002
ToppCellfacs-Brain_Myeloid-Cerebellum-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF18 GDA MAP4K1

5.25e-041604431f7acdc8b08152d5817fc53bbf47b4a22d9c91b5
ToppCellfacs-Lung-EPCAM-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD69 ARHGEF18 ZFYVE26

5.35e-041614438e787cc7f5e818cad1a6ed143a5fe310993e030b
ToppCellfacs-Lung-EPCAM-3m-Lymphocytic-CD8+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD69 ARHGEF18 ZFYVE26

5.35e-04161443ca9233370490e27b9a1892669d6b82db2136180e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM19 CSMD2 TENM3

5.35e-041614437d1bc73f4c82465b3f489d6737048b0cd54f22cf
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM19 CSMD2 TENM3

5.35e-04161443410eef62c83c704cbfc5a1b643c4db11bbdcd81f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM19 CSMD2 TENM3

5.35e-0416144371022485da6754a2b57b4c3e758e3de4c95cc292
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Neural-neural_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM19 CSMD2 TENM3

5.35e-0416144359ae8a7c9a04ecaa335b8064852a5a91a21780bd
ToppCellfacs-Lung-18m-Hematologic-myeloid-neutrophil|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GDA SYCP2 ADAM19

5.45e-04162443ad974426039f4952c59d27167eac24dc6ce63f5e
ToppCellfacs-Lung-18m-Hematologic-myeloid-neutrophil-neutrophil|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GDA SYCP2 ADAM19

5.45e-041624434e7e565091bce227d794a36af2e5dfc4a791efad
ToppCell343B-Fibroblasts-Fibroblast-D-|343B / Donor, Lineage, Cell class and subclass (all cells)

TENM3 KIAA1614 CPT1C

5.54e-041634438d2b2119c6b3d5b677da6f377fd85146590e1246
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAM19 AFF2 SPEG

5.54e-041634438f24cef152f5965727bbeee116bd26c75cbba82a
ToppCell343B-Fibroblasts-Fibroblast-D|343B / Donor, Lineage, Cell class and subclass (all cells)

TENM3 KIAA1614 CPT1C

5.54e-04163443acfb2ece6202479e615d54fd3ecb8b4a571b5a18
ToppCelldroplet-Lung-nan-18m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDA SYCP2 ADAM19

5.64e-041644430e424a69999eee13d27c4ff4f4ba3df64d3c2bda
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD69 ARHGEF18 MAP4K1

5.64e-0416444307d9252b267cb61c6050fbfa5b440aef1349f673
ToppCellfacs-Liver-Non-hepatocytes-24m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD69 ARHGEF18 MAP4K1

5.64e-041644437c016236f0cea38195c1373ebbd2c0b2b2ec81ad
ToppCelldroplet-Lung-nan-18m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDA SYCP2 ADAM19

5.64e-04164443fe9ecdd7a6cbaf910f42654eba75f79bea740a00
ToppCelldroplet-Fat-SCAT-30m-Lymphocytic-B_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD69 ODC1 MAP4K1

5.85e-041664434b31d2755108b2815316411a38bfb11fd30ef98a
ToppCellfacs-Kidney-nan-3m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPU CD69 ARHGEF18

5.85e-041664436a948aefd283a2572da37b59dbc142b6e686b024
ToppCellfacs-Kidney-nan-3m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPU CD69 ARHGEF18

5.85e-041664438d0c4eb90a2c006f96ae61d3d94c96fb64bc0c4d
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF18 TEX14 HAO2

5.85e-04166443bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCelldroplet-Fat-SCAT-30m-Lymphocytic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD69 ODC1 MAP4K1

5.85e-0416644367370c49d7aedcb4eca802095f06b30f6bbf8919
ToppCellfacs-Heart-RV-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD69 CLUH MAP4K1

5.85e-0416644316d42eda958b2a6f9d598e9b4b967505dee426ef
ToppCellfacs-Heart-RV-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD69 CLUH MAP4K1

5.85e-0416644308d7db4ff1c9c9cea3a36a87b8690838e79d4e0e
ToppCelldroplet-Fat-SCAT-30m-Lymphocytic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD69 ODC1 MAP4K1

5.85e-041664437f4e5976ede6478636aa567d6fc2b56ff7295fb8
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF18 TEX14 HAO2

5.85e-041664435e3b998d740b24f790fad37350d704ca0ea10b77
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CENPU ARHGEF18 TEX14

5.85e-04166443f4698fd08965936d51695d571bd10fb77330d916
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|343B / Donor, Lineage, Cell class and subclass (all cells)

CENPU ARHGEF18 TEX14

5.95e-041674437efa0081e79f22b219eac64ffcaedb2179cde299
ToppCellmild_COVID-19_(asymptomatic)-Plasmablast|World / disease group, cell group and cell class (v2)

CENPU EFCAB7 CPT1C

5.95e-04167443f26ae4de4804a3486502e3df37eabf3dfca688f5
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN10A CD69 MAP4K1

5.95e-04167443691f3589de0f8c13f9137812cfa9040c07d237b4
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TENM3 ABCA10 PHF24

6.05e-04168443d19a115365c5415e51c039718d7669de788fcf33
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-CD45____NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD69 ARHGEF18 ADAM19

6.16e-04169443573f85075d83a4baba41c3e24dc4d9831823a5e5
ToppCell343B-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

NMRK1 TEX14 VWCE

6.16e-04169443e68e6c24606fd46eca6f86bb63fa86ea17879ae2
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CSMD2 CPT1C KCNJ6

6.16e-0416944396a2aec9acf8a6f966973c035e5ade456cf47772
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCAF2 UNC5B SPEG

6.16e-0416944387116c33c5ca8cb1862e103e5607b1df4d264569
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD69 ARHGEF18 ADAM19

6.16e-04169443a24d12199b1a6d9cb243b3a68f4109d3a30b2dcb
DrugCatechin-(+,-) hydrate [7295-85-4]; Down 200; 13.8uM; PC3; HT_HG-U133A

CPSF1 AFF2 TENM3 ZZEF1 KDM4B FARP2

1.93e-061994364255_DN
Diseasemelanoma

CP MELTF ABL1 CPT1C KDM4B

2.66e-05248425C0025202
DiseaseNystagmus

AFF2 KCNJ6

4.08e-0421422HP_0000639
Diseasestomach cancer (is_marker_for)

GDA ABL1 KDM4B

1.09e-03142423DOID:10534 (is_marker_for)
Diseasecoronary aneurysm

CSMD2 UNC5B

1.14e-0335422EFO_1000881
Diseaseresting heart rate

SCN10A KLHL42 SPEG

1.25e-03149423EFO_0004351
DiseaseArthritis, Adjuvant-Induced

CD69 CP

1.49e-0340422C0003865
DiseaseArthritis, Collagen-Induced

CD69 CP

1.49e-0340422C0971858
DiseaseArthritis, Experimental

CD69 CP

1.49e-0340422C0993582
Diseaseneutrophil percentage of leukocytes

CD69 ARHGEF18 SPSB4 ADAM19 KDM4B

1.68e-03610425EFO_0007990
DiseaseDiabetes Mellitus, Sudden-Onset

CD69 CP

1.80e-0344422C4554117
DiseaseDiabetes Mellitus, Ketosis-Prone

CD69 CP

1.80e-0344422C3837958
DiseaseDiabetes, Autoimmune

CD69 CP

1.80e-0344422C0205734
DiseaseBrittle diabetes

CD69 CP

1.80e-0344422C0342302
DiseaseGastric Adenocarcinoma

TEX14 SPEG

1.88e-0345422C0278701
DiseaseDiabetes Mellitus, Insulin-Dependent

CD69 CP

1.88e-0345422C0011854
Diseaseresponse to xenobiotic stimulus

ABL1 CSMD2 TENM3

2.22e-03182423GO_0009410
DiseaseHepatitis, Toxic

CP GDA RDH13 HAO2

2.57e-03404424C0019193
DiseaseChemically-Induced Liver Toxicity

CP GDA RDH13 HAO2

2.57e-03404424C4279912
DiseaseDrug-Induced Liver Disease

CP GDA RDH13 HAO2

2.57e-03404424C0860207
DiseaseDrug-Induced Acute Liver Injury

CP GDA RDH13 HAO2

2.57e-03404424C3658290
DiseaseChemical and Drug Induced Liver Injury

CP GDA RDH13 HAO2

2.57e-03404424C4277682
DiseaseHepatitis, Drug-Induced

CP GDA RDH13 HAO2

2.57e-03404424C1262760
Diseasetype 1 diabetes mellitus

CENPU CD69 FARP2

4.94e-03242423MONDO_0005147

Protein segments in the cluster

PeptideGeneStartEntry
WPMCIGEVAHVSAEI

ACOT7L

36

Q6ZUV0
AWMAHIQRAVESCPD

ARHGEF18

776

Q6ZSZ5
VSDMFAAWSDHRPVC

CSMD2

386

Q7Z408
KVTRETHCWEFSPSM

ABCA10

796

Q8WWZ4
EVWTHGNMCEVSENP

ADAM19

261

Q9H013
CVEEILREMTHSWPT

AFF2

356

P51816
TSDIVHIWCPEGMKT

CENPU

231

Q71F23
VPHAWVMTCGTDGAI

CEP76

406

Q8TAP6
HMWPDTEGTFNVECL

CP

686

P00450
MPSDSHVSSCSEDWV

CD69

76

Q07108
MDHIEDPSWTPCVTN

KCNJ6

121

P48051
CLPIWHEMVETGGSE

CD300H

61

A0A0K2S4Q6
MEWIRETHIGDTVCP

KIAA1614

591

Q5VZ46
PTHWCLLVRENGTME

CPSF1

781

Q10570
TCAHAAGVLMEPDDW

KDM4B

881

O94953
GVMRCPHWTTEDGFE

RDH13

126

Q8NBN7
PISGHMWEFTLATEC

CPT1C

476

Q8TCG5
EGDPCDLWVTLHSMG

EFCAB7

476

A8K855
CVPHGAKDTEWRSVT

ABL1

721

P00519
EPDMCVGESVSWHLF

HEPHL1

281

Q6MZM0
TFVHSTWTCPMEVLR

GDA

16

Q9Y2T3
MLVEESDNEWSVPHC

FARP2

806

O94887
HSMVVDPWGTVVARC

NIT1

271

Q86X76
TLPVSCAWESGMKRH

ODC1

436

P11926
AAVWVPDSEATVCMR

PLEKHF2

146

Q9H8W4
LSCWLGEMSTEHRGP

MAP4K1

696

Q92918
SCWMESARHSVVSTD

NMRK1

71

Q9NWW6
CHWDSTRMSVEPVSS

TEX14

901

Q8IWB6
MEVRWCATSDPEQHK

MELTF

21

P08582
PVVTHQCWMDRTERS

TCAF2

591

A6NFQ2
HCLVWPDGEMSTARA

HAO2

81

Q9NYQ3
VMVAHESGRWNDVPC

NCAN

1186

O14594
AEVTEMAHTETGWSC

PHF24

171

Q9UPV7
SWTAPQAEHAMDCVR

CLUH

321

O75153
TWTHFGCPMEESENL

SPEG

1096

Q15772
PVVSAVWGHCEVTMR

SPSB4

211

Q96A44
MSSFPHVRWEAGIDD

SCN10A

1626

Q9Y5Y9
GREKTWFDMPCDATH

SYCP2

1261

Q9BX26
AMHESRSRWTEPGCS

VWCE

391

Q96DN2
CDTSMHISQVRLEWP

TENM3

1331

Q9P273
TMPHCAEVSARDWIF

UNC5B

621

Q8IZJ1
SSMDSHCPEAVEATW

ZZEF1

2336

O43149
SPRMGEECVSVWSHE

TMEM219

171

Q86XT9
RHQWVPDETESICMV

ZFYVE26

1806

Q68DK2
PSSDMWTLFETCDVH

KLHL42

366

Q9P2K6