Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	nuclear retinoic acid receptor binding	PRAMEF33 PRAMEF10 RARG PRAMEF17	2.09e-05	55	59	4	GO:0042974
GeneOntologyMolecularFunction	complement binding	CFH CFHR5 CR2	1.14e-04	32	59	3	GO:0001848
GeneOntologyMolecularFunction	complement component C3b binding	CFH CFHR5	5.56e-04	12	59	2	GO:0001851
GeneOntologyMolecularFunction	CCR5 chemokine receptor binding	JAK1 NES	6.56e-04	13	59	2	GO:0031730
GeneOntologyBiologicalProcess	platelet activation	SELP CFH DGKK ADAMTS18 PRKCQ SVEP1 GP5	3.31e-07	158	59	7	GO:0030168
GeneOntologyBiologicalProcess	regulation of platelet activation	SELP ADAMTS18 PRKCQ SVEP1 GP5	1.26e-06	66	59	5	GO:0010543
GeneOntologyBiologicalProcess	positive regulation of platelet activation	SELP SVEP1 GP5	7.91e-06	14	59	3	GO:0010572
GeneOntologyBiologicalProcess	blood coagulation	SELP CFH DGKK ADAMTS18 PRKCQ SVEP1 GP5	9.10e-06	260	59	7	GO:0007596
GeneOntologyBiologicalProcess	coagulation	SELP CFH DGKK ADAMTS18 PRKCQ SVEP1 GP5	1.06e-05	266	59	7	GO:0050817
GeneOntologyBiologicalProcess	hemostasis	SELP CFH DGKK ADAMTS18 PRKCQ SVEP1 GP5	1.11e-05	268	59	7	GO:0007599
GeneOntologyBiologicalProcess	complement activation, alternative pathway	CFH CFHR5 CR2	2.09e-05	19	59	3	GO:0006957
GeneOntologyBiologicalProcess	complement activation	CFH CFHR5 CR2 SVEP1	4.81e-05	70	59	4	GO:0006956
GeneOntologyBiologicalProcess	regulation of complement activation	CFH CR2 SVEP1	6.19e-05	27	59	3	GO:0030449
GeneOntologyBiologicalProcess	wound healing	STARD13 SELP CFH DGKK ADAMTS18 PRKCQ SVEP1 GP5	7.65e-05	493	59	8	GO:0042060
GeneOntologyBiologicalProcess	response to wounding	STARD13 SELP CFH DGKK ADAMTS18 CCN2 PRKCQ SVEP1 GP5	9.90e-05	659	59	9	GO:0009611
GeneOntologyBiologicalProcess	negative regulation of complement activation, classical pathway	CR2 SVEP1	2.23e-04	8	59	2	GO:0045959
GeneOntologyBiologicalProcess	regulation of body fluid levels	SELP CFH DGKK ADAMTS18 PRKCQ SVEP1 GP5	2.58e-04	442	59	7	GO:0050878
GeneOntologyBiologicalProcess	regulation of complement activation, classical pathway	CR2 SVEP1	3.57e-04	10	59	2	GO:0030450
GeneOntologyBiologicalProcess	protein O-linked glycosylation via threonine	GALNT3 GALNT6	3.57e-04	10	59	2	GO:0018243
GeneOntologyBiologicalProcess	homotypic cell-cell adhesion	CFH JAK1 ADAMTS18 PRKCQ	4.39e-04	124	59	4	GO:0034109
GeneOntologyBiologicalProcess	regulation of homotypic cell-cell adhesion	JAK1 ADAMTS18 PRKCQ	4.70e-04	53	59	3	GO:0034110
GeneOntologyBiologicalProcess	negative regulation of humoral immune response mediated by circulating immunoglobulin	CR2 SVEP1	5.21e-04	12	59	2	GO:0002924
GeneOntologyBiologicalProcess	regulation of humoral immune response	CFH CR2 SVEP1	6.78e-04	60	59	3	GO:0002920
GeneOntologyBiologicalProcess	glutamate receptor clustering	SSH1 CHRDL1	7.16e-04	14	59	2	GO:0097688
GeneOntologyBiologicalProcess	AMPA glutamate receptor clustering	SSH1 CHRDL1	7.16e-04	14	59	2	GO:0097113
GeneOntologyBiologicalProcess	negative regulation of complement activation	CR2 SVEP1	7.16e-04	14	59	2	GO:0045916
MousePheno	abnormal male germ cell apoptosis	LHCGR PRAMEF33 PRAMEF10 GALNT3 PRAMEF17 CCIN SLX4	1.46e-05	236	48	7	MP:0008280
MousePheno	abnormal male germ cell physiology	LHCGR PRAMEF33 PRAMEF10 GALNT3 PRAMEF17 CCIN SLX4	1.81e-05	244	48	7	MP:0020362
MousePheno	abnormal germ cell physiology	LHCGR PRAMEF33 PRAMEF10 GALNT3 PRAMEF17 CCIN SLX4	3.23e-05	267	48	7	MP:0020363
MousePheno	increased male germ cell apoptosis	LHCGR PRAMEF33 PRAMEF10 GALNT3 PRAMEF17 CCIN	4.32e-05	189	48	6	MP:0014052
MousePheno	abnormal tail morphology	JAK1 PRAMEF33 PRAMEF10 ARSB ZNF174 PRAMEF17 SLX4 SVEP1	6.11e-05	403	48	8	MP:0002111
MousePheno	abnormal venous thrombosis	CFH PEX1	1.15e-04	5	48	2	MP:0031158
MousePheno	abnormal response to vitamins	RARG KCP	1.15e-04	5	48	2	MP:0003639
Domain	Sushi	SELP CFH CFHR5 CR2 SVEP1	4.30e-07	52	55	5	PF00084
Domain	CCP	SELP CFH CFHR5 CR2 SVEP1	5.21e-07	54	55	5	SM00032
Domain	SUSHI	SELP CFH CFHR5 CR2 SVEP1	6.26e-07	56	55	5	PS50923
Domain	Sushi_SCR_CCP_dom	SELP CFH CFHR5 CR2 SVEP1	6.85e-07	57	55	5	IPR000436
Domain	VWC	KCP CHRDL1 CCN2	7.51e-05	28	55	3	PF00093
Domain	VWFC_1	KCP CHRDL1 CCN2	1.61e-04	36	55	3	PS01208
Domain	VWC	KCP CHRDL1 CCN2	1.89e-04	38	55	3	SM00214
Domain	VWFC_2	KCP CHRDL1 CCN2	1.89e-04	38	55	3	PS50184
Domain	VWF_dom	KCP CHRDL1 CCN2	2.56e-04	42	55	3	IPR001007
Domain	ZF_DAG_PE_1	DGKK TNS2 PRKCQ	8.87e-04	64	55	3	PS00479
Domain	ZF_DAG_PE_2	DGKK TNS2 PRKCQ	8.87e-04	64	55	3	PS50081
Domain	C1	DGKK TNS2 PRKCQ	9.28e-04	65	55	3	SM00109
Domain	PE/DAG-bd	DGKK TNS2 PRKCQ	9.70e-04	66	55	3	IPR002219
Domain	PRAME_family	PRAMEF10 PRAMEF17	1.41e-03	19	55	2	IPR026271
Domain	C2H2_Znf_fam	ZNF174 ZNF518B	2.25e-03	24	55	2	IPR027775
Domain	Ricin_B_lectin	GALNT3 GALNT6	2.45e-03	25	55	2	PF00652
Domain	-	LHCGR TRIL PRAMEF10 PRAMEF17 GP5	2.50e-03	321	55	5	3.80.10.10
Domain	L_dom-like	LHCGR TRIL PRAMEF10 PRAMEF17 GP5	2.75e-03	328	55	5	IPR032675
Domain	LRRNT	LHCGR TRIL GP5	3.02e-03	98	55	3	IPR000372
Domain	LRRNT	LHCGR TRIL GP5	3.02e-03	98	55	3	SM00013
Domain	RICIN	GALNT3 GALNT6	3.06e-03	28	55	2	SM00458
Domain	RICIN_B_LECTIN	GALNT3 GALNT6	3.06e-03	28	55	2	PS50231
Domain	Ricin_B_lectin	GALNT3 GALNT6	3.51e-03	30	55	2	IPR000772
Domain	Glycos_transf_2	GALNT3 GALNT6	3.51e-03	30	55	2	PF00535
Domain	Glyco_trans_2-like	GALNT3 GALNT6	3.51e-03	30	55	2	IPR001173
Domain	LRRCT	TRIL GP5	3.99e-03	32	55	2	PF01463
Pubmed	Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.	PRAMEF33 PRAMEF10 RARG PRAMEF17	4.30e-07	35	61	4	19389355
Pubmed	Variations in the complement regulatory genes factor H (CFH) and factor H related 5 (CFHR5) are associated with membranoproliferative glomerulonephritis type II (dense deposit disease).	CFH CFHR5	3.03e-06	2	61	2	16299065
Pubmed	Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3.	GALNT3 GALNT6	3.03e-06	2	61	2	31932717
Pubmed	The polypeptide GALNT6 Displays Redundant Functions upon Suppression of its Closest Homolog GALNT3 in Mediating Aberrant O-Glycosylation, Associated with Ovarian Cancer Progression.	GALNT3 GALNT6	3.03e-06	2	61	2	31071912
Pubmed	Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.	PRAMEF33 PRAMEF10 PRAMEF17	5.73e-06	20	61	3	26694250
Pubmed	Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.	PRAMEF33 PRAMEF10 PRAMEF17	7.72e-06	22	61	3	31729367
Pubmed	A complement receptor locus: genes encoding C3b/C4b receptor and C3d/Epstein-Barr virus receptor map to 1q32.	CFH CR2	9.07e-06	3	61	2	3782802
Pubmed	Targeted inhibition of the complement alternative pathway with complement receptor 2 and factor H attenuates collagen antibody-induced arthritis in mice.	CFH CR2	9.07e-06	3	61	2	19828624
Pubmed	MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.	PRAMEF33 PRAMEF10 PRAMEF17	1.15e-05	25	61	3	37451217
Pubmed	Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.	PRAMEF33 PRAMEF10 PRAMEF17	1.63e-05	28	61	3	25089626
Pubmed	Protective chromosome 1q32 haplotypes mitigate risk for age-related macular degeneration associated with the CFH-CFHR5 and ARMS2/HTRA1 loci.	CFH CFHR5	1.81e-05	4	61	2	34563268
Pubmed	RARγ promotes the invasion and metastasis of thyroid carcinoma by activating the JAK1-STAT3-CD24/MMPs axis.	JAK1 RARG	1.81e-05	4	61	2	37897947
Pubmed	Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.	PRAMEF33 PRAMEF10 PRAMEF17	2.02e-05	30	61	3	38786026
Pubmed	Risk of non-Hodgkin lymphoma in association with germline variation in complement genes.	CFH CFHR5 CR2	2.23e-05	31	61	3	19344414
Pubmed	The cell-layer- and cell-type-specific distribution of GalNAc-transferases in the ocular surface epithelia is altered during keratinization.	GALNT3 GALNT6	3.02e-05	5	61	2	12506059
Pubmed	Molecular cloning of rat and mouse membrane cofactor protein (MCP, CD46): preferential expression in testis and close linkage between the mouse Mcp and Cr2 genes on distal chromosome 1.	CFH CR2	3.02e-05	5	61	2	9799332
Pubmed	Complement-dependent P-selectin expression and injury following ischemic stroke.	SELP CR2	3.02e-05	5	61	2	17082645
Pubmed	Targeted complement inhibitors protect against posttransplant cardiac ischemia and reperfusion injury and reveal an important role for the alternative pathway of complement activation.	CFH CR2	3.02e-05	5	61	2	20962256
Pubmed	Dimerization of complement factor H-related proteins modulates complement activation in vivo.	CFH CFHR5	4.52e-05	6	61	2	23487775
Pubmed	Sequence and Expression of Complement Factor H Gene Cluster Variants and Their Roles in Age-Related Macular Degeneration Risk.	CFH CFHR5	4.52e-05	6	61	2	27196323
Pubmed	The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration.	CFH CFHR5	4.52e-05	6	61	2	18541031
Pubmed	Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications.	CFH CFHR5	4.52e-05	6	61	2	17438673
Pubmed	Atypical postinfectious glomerulonephritis is associated with abnormalities in the alternative pathway of complement.	CFH CFHR5	4.52e-05	6	61	2	23235567
Pubmed	Mutations in alternative pathway complement proteins in American patients with atypical hemolytic uremic syndrome.	CFH CFHR5	6.32e-05	7	61	2	20513133
Pubmed	Genotoxic stress-induced activation of Plk3 is partly mediated by Chk2.	TNS2 SLX4	8.42e-05	8	61	2	12548019
Pubmed	Genetic organization of complement receptor-related genes in the mouse.	CFH CR2	8.42e-05	8	61	2	2564419
Pubmed	C3 Glomerulopathy	CFH CFHR5	8.42e-05	8	61	2	20301598
Pubmed	DUX is a non-essential synchronizer of zygotic genome activation.	PRAMEF33 PRAMEF10 PRAMEF17	9.49e-05	50	61	3	31806660
Pubmed	Epidemiological approach to identifying genetic predispositions for atypical hemolytic uremic syndrome.	CFH CFHR5	1.08e-04	9	61	2	20059470
Pubmed	FHR-1 Binds to C-Reactive Protein and Enhances Rather than Inhibits Complement Activation.	CFH CFHR5	1.08e-04	9	61	2	28533443
Pubmed	Platelet alpha-granules.	SELP GP5	1.08e-04	9	61	2	8467233
Pubmed	Stage-specific modulation of cortical neuronal development by Mmu-miR-134.	NES CHRDL1	1.65e-04	11	61	2	21228099
Pubmed	Genome-wide association study of body mass index in 23 000 individuals with and without asthma.	STARD13 PRKCQ	1.65e-04	11	61	2	23517042
Pubmed	Dual Role of Rbpj in the Maintenance of Neural Progenitor Cells and Neuronal Migration in Cortical Development.	NES CCN2	1.97e-04	12	61	2	32780108
Pubmed	Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.	STARD13 PRAMEF33 PRAMEF10 PEX1 PRAMEF17	2.72e-04	326	61	5	17015433
Pubmed	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	CFH CFHR5	2.72e-04	14	61	2	23381943
Pubmed	Genetic factors in nonsmokers with age-related macular degeneration revealed through genome-wide gene-environment interaction analysis.	CFH CFHR5	2.72e-04	14	61	2	23577725
Pubmed	Mapping of quantitative trait loci determining NK cell-mediated resistance to MHC class I-deficient bone marrow grafts in perforin-deficient mice.	JAK1 PRKCQ	3.13e-04	15	61	2	17114464
Pubmed	Pax6 mediates ß-catenin signaling for self-renewal and neurogenesis by neocortical radial glial stem cells.	NES CCN2	3.13e-04	15	61	2	24115331
Pubmed	Dephosphorylation of the transcriptional cofactor NACA by the PP1A phosphatase enhances cJUN transcriptional activity and osteoblast differentiation.	NES PPP1R18	3.13e-04	15	61	2	30948508
Pubmed	Genetic influences on the end-stage effector phase of arthritis.	SELP CFH	3.57e-04	16	61	2	11489951
Pubmed	Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.	PRAMEF10 PRAMEF17	4.05e-04	17	61	2	23565261
Pubmed	Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.	PRAMEF10 PRAMEF17	4.05e-04	17	61	2	37781892
Pubmed	The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.	PRAMEF10 PRAMEF17	4.55e-04	18	61	2	23894331
Pubmed	Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.	PRAMEF10 PRAMEF17	4.55e-04	18	61	2	12890732
Pubmed	Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.	PRAMEF10 PRAMEF17	4.55e-04	18	61	2	29731491
Pubmed	Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.	PRAMEF10 PRAMEF17	4.55e-04	18	61	2	14675769
Pubmed	Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.	PRAMEF10 PRAMEF17	4.55e-04	18	61	2	39181896
Pubmed	RP58/ZNF238 directly modulates proneurogenic gene levels and is required for neuronal differentiation and brain expansion.	NES CCN2	5.08e-04	19	61	2	22095278
Pubmed	Genome-wide association study identifies susceptibility loci for IgA nephropathy.	CFH CFHR5	5.08e-04	19	61	2	21399633
Pubmed	Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.	PRAMEF10 PRAMEF17	5.08e-04	19	61	2	28604677
Pubmed	Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.	PRAMEF10 PRAMEF17	5.63e-04	20	61	2	16580637
Pubmed	Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling.	NES RARG	5.63e-04	20	61	2	28154153
Pubmed	Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.	PRAMEF10 PRAMEF17	5.63e-04	20	61	2	21425410
Pubmed	Overexpression of Galnt3 in chondrocytes resulted in dwarfism due to the increase of mucin-type O-glycans and reduction of glycosaminoglycans.	GALNT3 GALNT6	6.83e-04	22	61	2	25107907
Pubmed	Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.	PRAMEF10 PRAMEF17	7.48e-04	23	61	2	19480014
Pubmed	Loss of the disease-associated glycosyltransferase Galnt3 alters Muc10 glycosylation and the composition of the oral microbiome.	GALNT3 GALNT6	8.15e-04	24	61	2	31882545
Pubmed	Genetic contributions of nonautoimmune SWR mice toward lupus nephritis.	CFH CR2	8.15e-04	24	61	2	11739537
Pubmed	Galnt11 regulates kidney function by glycosylating the endocytosis receptor megalin to modulate ligand binding.	GALNT3 GALNT6	8.15e-04	24	61	2	31740596
Pubmed	Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.	PRAMEF10 PRAMEF17	8.84e-04	25	61	2	12620990
Pubmed	Ccm3, a gene associated with cerebral cavernous malformations, is required for neuronal migration.	NES CCN2	8.84e-04	25	61	2	24595293
Pubmed	Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.	PRAMEF10 PRAMEF17	9.57e-04	26	61	2	18500982
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	PELP1 NOL6 NUP88 TRRAP SLX4	1.05e-03	440	61	5	34244565
Pubmed	Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.	STARD13 CFH	1.11e-03	28	61	2	33953184
Pubmed	TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma.	NUP88 TRRAP	1.11e-03	28	61	2	29653964
Pubmed	A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.	NUP88 PPP1R18 TNS2	1.19e-03	118	61	3	30979931
Pubmed	Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas.	STARD13 CCN2	1.28e-03	30	61	2	23175628
Pubmed	D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function.	NES PPP1R15A	1.36e-03	31	61	2	22925884
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	STARD13 CFH PRAMEF33 PRAMEF10 PUS10 PRAMEF17 TRRAP SLX4	1.42e-03	1242	61	8	30973865
Pubmed	LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.	PRAMEF10 PRAMEF17	1.45e-03	32	61	2	37889087
Pubmed	Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.	SELP PRR7	1.54e-03	33	61	2	22703881
Pubmed	Cold-induced protein RBM3 orchestrates neurogenesis via modulating Yap mRNA stability in cold stress.	NES CCN2	1.54e-03	33	61	2	30037926
Pubmed	MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons.	ADAMTS18 CCN2	1.73e-03	35	61	2	22407321
Cytoband	1p36.21	PRAMEF33 PRAMEF10 PRAMEF17	8.37e-05	63	61	3	1p36.21
Cytoband	1q32	CFH CR2	1.96e-03	49	61	2	1q32
Cytoband	Ensembl 112 genes in cytogenetic band chr12q13	RARG TNS2 GALNT6 PMEL	2.45e-03	423	61	4	chr12q13
Cytoband	17p13.2	PELP1 NUP88	2.46e-03	55	61	2	17p13.2
Cytoband	2p21	LHCGR PREPL	3.02e-03	61	61	2	2p21
Cytoband	12q13	RARG GALNT6	4.07e-03	71	61	2	12q13
Cytoband	16p13.3	CEMP1 ZNF174 SLX4	4.25e-03	244	61	3	16p13.3
Cytoband	9p13.3	NOL6 CCIN	4.53e-03	75	61	2	9p13.3
Cytoband	Ensembl 112 genes in cytogenetic band chr1q31	CFH CFHR5	4.53e-03	75	61	2	chr1q31
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SELP CFH CFHR5 CR2 SVEP1	1.79e-07	57	41	5	1179
GeneFamily	Complement system\|Sushi domain containing	CFH CFHR5 CR2	7.34e-05	36	41	3	492
GeneFamily	Polypeptide N-acetylgalactosaminyltransferases	GALNT3 GALNT6	9.29e-04	20	41	2	433
GeneFamily	PRAME family	PRAMEF10 PRAMEF17	1.34e-03	24	41	2	686
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PPP1R12B PPP1R18 PPP1R15A	7.96e-03	181	41	3	694
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-SVEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SELP NES C2CD4B SSH1 CCDC3 CCN2	2.55e-07	192	61	6	c3dda7c48732b0b8bde36de282d64192f5e9b98f
ToppCell	343B-Endothelial_cells-Endothelial-B_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SELP CFH C2CD4B CCN2 ARL15 PRR7	2.71e-07	194	61	6	582db7f7fa9aa08027ae18ed607945b5d1dc908a
ToppCell	343B-Endothelial_cells-Endothelial-B_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SELP CFH C2CD4B CCN2 ARL15 PRR7	2.71e-07	194	61	6	bda89111386398a072b70e8153b2a762298a047a
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARSB PRKCQ GALNT6 UTY SLX4	2.24e-06	154	61	5	75eac6970259a6916fcfa6d3400509cfa2d98d9d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH TRIL PLK5 CCN2 SVEP1	3.05e-06	164	61	5	01a7c335897128d3478b8b9b44fb461cab493084
ToppCell	390C-Fibroblasts-Fibroblast-G\|390C / Donor, Lineage, Cell class and subclass (all cells)	CFH CCN2 PMEL SVEP1 IHO1	4.81e-06	180	61	5	137fc14859c89e1ecd98bee388bb58c04b835847
ToppCell	390C-Fibroblasts-Fibroblast-G-\|390C / Donor, Lineage, Cell class and subclass (all cells)	CFH CCN2 PMEL SVEP1 IHO1	4.81e-06	180	61	5	cd6790de050151fedfa2c5ea6ad58b72665414b2
ToppCell	facs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD13 CFH PPP1R12B CCN2 SVEP1	5.08e-06	182	61	5	c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCell	facs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STARD13 CFH PPP1R12B CCN2 SVEP1	5.08e-06	182	61	5	dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCell	Endothelial-A-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	SELP NES C2CD4B CCDC3 CCN2	5.50e-06	185	61	5	ae49c61f6ecf128fe2a958b8c75c83688da75f59
ToppCell	Endothelial-A-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	SELP NES C2CD4B CCDC3 CCN2	5.79e-06	187	61	5	fd93f3f4b82dae3bf4eef245bfedc2a9e3251b61
ToppCell	Endothelial-A-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	SELP NES C2CD4B CCDC3 CCN2	5.79e-06	187	61	5	febe0b99a6a815ce687160a0e7af55228b1d5beb
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH NES C2CD4B CCDC3 TNS2	5.94e-06	188	61	5	a37edd8f9e4a4e336b5acbb0407d3d275975cee8
ToppCell	Control-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	SELP C2CD4B ARSB SSH1 CCN2	6.26e-06	190	61	5	4e30155203b4a8c5e496fcbe9348b67b98ebc625
ToppCell	343B-Endothelial_cells-Endothelial-B_(Artery)\|343B / Donor, Lineage, Cell class and subclass (all cells)	SELP CFH C2CD4B CCN2 ARL15	6.42e-06	191	61	5	27a532a35d9e8822014f581fd56c4ca62e39f8fe
ToppCell	343B-Endothelial_cells-Endothelial-B_(Artery)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	SELP CFH C2CD4B CCN2 ARL15	6.42e-06	191	61	5	1dfcff08e01e6a695953334342bcfde04ba005ad
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CFH NES CCDC3 TNS2 ARL15	6.75e-06	193	61	5	cc355b2ed6510619cad969ae074126d7c8db784d
ToppCell	10x5'v1-week_12-13-Hematopoietic-MK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SELP CFH PRKCQ ARL15 GP5	6.92e-06	194	61	5	245a3eb6db9c862b73ad34a8cd2898a3688c16f6
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH CCDC3 CHRDL1 CCN2 SVEP1	7.28e-06	196	61	5	fcb275746bf51269ed8ba4cf93edb054a45f1ccd
ToppCell	Parenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CFH TRIL PPP1R12B CCDC3 CHRDL1	7.46e-06	197	61	5	31c8d6e565bbdc37843ce871fe91845b0cc18a9f
ToppCell	distal-1-Endothelial-Bronchial_Vessel_1\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SELP C2CD4B CCDC3 ADAMTS18 CCN2	7.64e-06	198	61	5	5cd81fe1a21c0e1a7f0d5a62ddf8e422b05aedc7
ToppCell	distal-3-Endothelial-Bronchial_Vessel_1\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SELP NES C2CD4B ADAMTS18 CCN2	7.64e-06	198	61	5	00fdee373eaa43c9ce897f2ba2ecbe94cedea93a
ToppCell	ASK452-Endothelial\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	STARD13 SELP NES C2CD4B SSH1	7.83e-06	199	61	5	0bc97a9a78aaafd1554ae6a61356ed9ea4983fa5
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFH NES CCDC3 KIAA0087 ARL15	7.83e-06	199	61	5	6a2943a23fdd2ec814662db7c21a0d6804a6cbbc
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_venous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SELP NES C2CD4B ADAMTS18 CCN2	7.83e-06	199	61	5	6fb81388c5045e81c3849a7136bdff3f953f044e
ToppCell	proximal-mesenchymal-Vascular_Smooth_Muscle-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TRIL NES PPP1R12B CCDC3 CCN2	8.02e-06	200	61	5	5c0135d3cb6f7fa904e9760904dfe5f11c7e9102
ToppCell	proximal-3-mesenchymal-Vascular_Smooth_Muscle\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TRIL NES PPP1R12B CCDC3 CCN2	8.02e-06	200	61	5	870ab11343711f64fe6d6a858fc420fe17f1636a
ToppCell	Parenchymal-10x3prime_v2-Stromal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CFH PPP1R12B CHRDL1 CCN2 SVEP1	8.02e-06	200	61	5	f6be0f24e607abb9007823a54fb0b24d04990a89
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELP NES C2CD4B ADAMTS18 CCN2	8.02e-06	200	61	5	310c75e13be9194312a8b686804edcf13d44caf5
ToppCell	proximal-mesenchymal-Vascular_Smooth_Muscle\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TRIL NES PPP1R12B CCDC3 CCN2	8.02e-06	200	61	5	22892afca3666e944102c231b3f10340d8391364
ToppCell	frontal_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TRIL GALNT3 PRKCQ PMEL	3.34e-05	133	61	4	63d2f096ae47d9b587acc6c5fbd346e5e58842b8
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Trm_Tgd\|lymph-node_spleen / Manually curated celltypes from each tissue	SSH1 HECTD2 KCP GALNT6	6.07e-05	155	61	4	b0e456c4915076e1d38282e116a6eb3230ae80dc
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PEX1 KCP PRKCQ BRWD1	7.03e-05	161	61	4	5fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PPP1R18 PRKCQ GALNT6 PMEL	7.92e-05	166	61	4	a41a20cef053c67da2d435e3e132ce28f1661c03
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAK1 PPP1R18 PRKCQ GALNT6	8.10e-05	167	61	4	d72b08b3cbc34b30a11dcf512e472b64d1606ec1
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAK1 PPP1R18 PRKCQ GALNT6	8.10e-05	167	61	4	22f7384ff2044898d7b0b01cb9d9a3cbaa93a9a3
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NES APEX2 PUS10 PPP1R12B	8.48e-05	169	61	4	7cb1b87be66a22fe5731bb1b55bc515920fe3e8b
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH RTL1 TNS2 SVEP1	8.48e-05	169	61	4	c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH CHRDL1 CCN2 SVEP1	9.08e-05	172	61	4	1ef243bce63d841c25e4b74d029d1377f84bcc3d
ToppCell	Adult-Mesenchymal-pericyte_cell-D231\|Adult / Lineage, Cell type, age group and donor	NES CCDC3 KCP C15orf39	9.08e-05	172	61	4	858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH NES PCARE CCN2	9.08e-05	172	61	4	6c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH CHRDL1 CCN2 SVEP1	9.08e-05	172	61	4	ab1c81be29f93ca8920c6ab5ab92f497a9256d3f
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT3 CCDC3 KCP CCN2	9.50e-05	174	61	4	a0ccda8fd6f55251cdeff24cf66e72e4a31d2104
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH PPP1R12B CHRDL1 CCN2	9.71e-05	175	61	4	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	facs-Spleen-nan-18m-Lymphocytic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARSB GALNT3 PPP1R18 PRKCQ	9.92e-05	176	61	4	a23d484aff5ad094333b2feae9106ca219514711
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	CFH CHRDL1 CCN2 SVEP1	9.92e-05	176	61	4	510f9a14dc1c151d24d079e0cc004cdf4f86336c
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	NES CCDC3 ADAMTS18 SVEP1	1.04e-04	178	61	4	e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCell	COPD-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	SELP C2CD4B SSH1 CCN2	1.06e-04	179	61	4	9968da1adcb561d9bf167a42ab5d9de85c071c4a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFH TRIL CCN2 SVEP1	1.08e-04	180	61	4	ea7a1ccf0dd3bb5af5df87501f873e7339a824b3
ToppCell	facs-Spleen-nan-3m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH JAK1 CR2 BRWD1	1.08e-04	180	61	4	87fb1fdbc49c808bb5f6fe9fb747057b45fa78d0
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NES C2CD4B CCN2 ARL15	1.13e-04	182	61	4	0639011cdd1c437ea8b7230896a4e6e5d7244ac2
ToppCell	tumor_Lymph_Node_/_Brain-Endothelial_cells\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	SELP NES C2CD4B CCDC3	1.13e-04	182	61	4	d7cce5dd7046f06bf40f00c9dbfa610722b03333
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Stroma____kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH TRIL PPP1R12B CCN2	1.15e-04	183	61	4	8de4b616a06be03e1cb6ae6a9ce6bf06485629d3
ToppCell	COPD-Endothelial-VE_Venous\|COPD / Disease state, Lineage and Cell class	SELP C2CD4B SSH1 CCN2	1.18e-04	184	61	4	44d716e7ba46a1ed03f5992631289653f8fd7d5e
ToppCell	COPD-Endothelial-VE_Peribronchial\|World / Disease state, Lineage and Cell class	SELP NES C2CD4B SSH1	1.20e-04	185	61	4	4abe04198ab5047c211f8d09cdb9650fa52a3cd6
ToppCell	Mild-CD4+_T\|Mild / Disease group and Cell class	CFH RARG TNS2 PPP1R15A	1.20e-04	185	61	4	c28ecb63146de1b02418e5a4fad0ae7c2b66a41d
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH CHRDL1 CCN2 SVEP1	1.23e-04	186	61	4	5473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell	COPD-Endothelial-VE_Peribronchial\|COPD / Disease state, Lineage and Cell class	SELP NES C2CD4B SSH1	1.23e-04	186	61	4	23c7d0e8372a71546d687278b985f761d282f92f
ToppCell	Adult-Mesenchymal-pericyte_cell\|Adult / Lineage, Cell type, age group and donor	NES CCDC3 KCP TNS2	1.25e-04	187	61	4	62759efb660179402fb574ce5701c89a2e17bcfe
ToppCell	10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-ILC_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CFH JAK1 RARG KIAA0087	1.25e-04	187	61	4	f31d865ce2a21bdf64dbe29ee3e4505ab482604a
ToppCell	tumor_Lymph_Node_/_Brain-Endothelial_cells-Tumor_ECs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	SELP NES C2CD4B CCDC3	1.25e-04	187	61	4	be5f8c5802b0fa8cc1e274fdf06b13eb8ceb8ad4
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH CHRDL1 CCN2 SVEP1	1.28e-04	188	61	4	c32d023a69b6da79687ff8fa7485e7499db57046
ToppCell	Control-Endothelial-VE_Peribronchial\|Control / Disease state, Lineage and Cell class	SELP NES C2CD4B CCN2	1.28e-04	188	61	4	f5b7dbc89f992c13280d36a34935be83906b1bc0
ToppCell	normal_Lung-Fibroblasts-Smooth_muscle_cells\|normal_Lung / Location, Cell class and cell subclass	CFH NES PPP1R12B CCN2	1.28e-04	188	61	4	fd70fb89570f014d1299c60fe017dc09f24e57c6
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HECTD2 PPP1R12B CCDC3 CHRDL1	1.28e-04	188	61	4	293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CFH CHRDL1 CCN2 SVEP1	1.28e-04	188	61	4	1cd5a4d744bd3777246958ea5eb94388a5cbad81
ToppCell	Substantia_nigra-Endothelial\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CFH NES TNS2 CCN2	1.31e-04	189	61	4	bef8234bd9c4d6e3cdef0791d8066b39ba56ebba
ToppCell	Globus_pallidus-Endothelial\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CFH NES TNS2 CCN2	1.31e-04	189	61	4	ad7dc9d25edd68fb624380a082c389fe7d640e7d
ToppCell	Endothelial-A-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	SELP NES C2CD4B CCN2	1.33e-04	190	61	4	6e83fa0eb8cabe0ffb35375f16e6bf3755ec4977
ToppCell	343B-Endothelial_cells-Endothelial-A_(Artery)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	SELP NES C2CD4B CCDC3	1.33e-04	190	61	4	ac2eb1e51459d187095152e0cd41ae54c1025c6f
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SELP NES ADAMTS18 TNS2	1.33e-04	190	61	4	141266bf411ea675fbf889b20c1b08673c45ff95
ToppCell	343B-Endothelial_cells-Endothelial-A_(Artery)\|343B / Donor, Lineage, Cell class and subclass (all cells)	SELP NES C2CD4B CCDC3	1.33e-04	190	61	4	6010f16378f2d9cde37c7e7db6a7d9666edaddcc
ToppCell	ASK454-Mesenchymal\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	CFH TRIL CHRDL1 SVEP1	1.36e-04	191	61	4	e30ae7a12439f8a79820b13f03e822c1223fd0cb
ToppCell	ASK454-Mesenchymal-Fibroblast\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	CFH TRIL CHRDL1 SVEP1	1.36e-04	191	61	4	1726add3f392a061536b7aff72ba84303f4a0b1f
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH CHRDL1 CCN2 SVEP1	1.36e-04	191	61	4	4e4488380379ed29d7898bae4e24221e7c67eb9d
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CFH CCDC3 TNS2 CCN2	1.39e-04	192	61	4	fee99ca7e658963acf968aa724ef8c96cfc00a5d
ToppCell	Control-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	SELP CFH CCN2 ARL15	1.39e-04	192	61	4	7e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPP1R12B CHRDL1 CCN2 PPP1R15A	1.41e-04	193	61	4	4aa976b596830b585e8d9c808d5072ed23d13a7c
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELP SSH1 TNS2 ARL15	1.41e-04	193	61	4	1e6e2d786511cc40241197368f5df20c20b882f3
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CFH NES CCDC3 CCN2	1.41e-04	193	61	4	5e46a9f65e85aca78f825fdef88a95b97eec8743
ToppCell	Control-Endothelial-VE_Arterial\|World / Disease state, Lineage and Cell class	SELP NES C2CD4B CCN2	1.41e-04	193	61	4	52c0f2c7af57436f23e0c0e0c87086c47695e2c4
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PPP1R12B CHRDL1 CCN2 PPP1R15A	1.41e-04	193	61	4	5578f7cb3ec68c9a38cc5304b618b81283024d5e
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CCDC3 CCN2 PPP1R15A SVEP1	1.41e-04	193	61	4	cf3cbf79ccd34ddcf06ec6194a18a7afd7f91f39
ToppCell	390C-Endothelial_cells-Endothelial-B_(Artery)\|390C / Donor, Lineage, Cell class and subclass (all cells)	SELP NES C2CD4B CCN2	1.44e-04	194	61	4	f8a59bd4609d147d8a706bf606e9e8173c9992a3
ToppCell	356C-Endothelial_cells-Endothelial-A_(Artery)\|356C / Donor, Lineage, Cell class and subclass (all cells)	SELP NES C2CD4B CCN2	1.44e-04	194	61	4	2e5b195e02dcd5e9432b9a98b22e0478e65b9ba2
ToppCell	LV-02._Fibroblast_II\|LV / Chamber and Cluster_Paper	CFH CCN2 ARL15 SVEP1	1.44e-04	194	61	4	014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell	390C-Endothelial_cells-Endothelial-B_(Artery)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	SELP NES C2CD4B CCN2	1.44e-04	194	61	4	04b1acc2e879feafb43f75435281c5acd8d23be2
ToppCell	(6)_Endothelial-B_(Artery)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	SELP NES C2CD4B CCN2	1.44e-04	194	61	4	0cf4e67d4024652794b5bfdd4a71a7d98900b4c8
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PPP1R12B CCDC3 CCN2 SVEP1	1.44e-04	194	61	4	5f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCell	356C-Endothelial_cells-Endothelial-A_(Artery)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	SELP NES C2CD4B CCN2	1.44e-04	194	61	4	b6b5b0ab506b05a005ba8a05a3c7f4c725ba9200
ToppCell	Control-Stromal-Myofibroblast\|World / Disease state, Lineage and Cell class	CFH CHRDL1 CCN2 SVEP1	1.44e-04	194	61	4	3c2266772c5b56e8e02a461e5193e29588028ee9
ToppCell	Control-Stromal-Myofibroblast\|Control / Disease state, Lineage and Cell class	CFH CHRDL1 CCN2 SVEP1	1.47e-04	195	61	4	ffcf76cd72e43d8cf1058a49c76e0956065038bc
ToppCell	IPF-Endothelial-VE_Peribronchial\|World / Disease state, Lineage and Cell class	SELP NES C2CD4B CCDC3	1.47e-04	195	61	4	120296531bbc8080dcabacbd64733cc1dc34603a
ToppCell	ASK428-Mesenchymal\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	CFH CCDC3 CHRDL1 CCN2	1.47e-04	195	61	4	2b156163975d9a3d3fda1402acd9831d0fdc9e25
ToppCell	IPF-Stromal-Fibroblast\|World / Disease state, Lineage and Cell class	CFH CHRDL1 CCN2 SVEP1	1.47e-04	195	61	4	9c32756edb54f0c211185d9a98073fe01fd1526a
ToppCell	Control-Endothelial-VE_Arterial\|Control / Disease state, Lineage and Cell class	SELP NES C2CD4B CCN2	1.47e-04	195	61	4	56c66a3655820961e1390b8f4bcc5618e8d0c5a8
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SELP C2CD4B ARSB SSH1	1.47e-04	195	61	4	818bc18c5834238e5f733cac6fe928ed0788f57d
ToppCell	10x5'v1-week_12-13-Hematopoietic-MK-early_MK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SELP CFH PRKCQ ARL15	1.47e-04	195	61	4	fa5fc6f605deb5cae96eec14ba4000b19f877ba6
ToppCell	10x3'2.3-week_12-13-Hematopoietic-MK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SELP CFH PRKCQ ARL15	1.47e-04	195	61	4	1e794839a251fbc6e6ce419b4c457ead35a04735
ToppCell	IPF-Endothelial-VE_Peribronchial\|IPF / Disease state, Lineage and Cell class	SELP NES C2CD4B CCDC3	1.47e-04	195	61	4	2c3ad3cb79f11119ac69c413a938d21199145040
Drug	Norethindrone [68-22-4]; Down 200; 13.4uM; MCF7; HT_HG-U133A	STARD13 ZNF174 PPP1R12B C15orf39 ARL15 UTY	1.32e-05	197	60	6	7414_DN
Drug	Pirenzepine dihydrochloride [29868-97-1]; Up 200; 9.4uM; PC3; HT_HG-U133A	ARSB RARG ZNF174 PPP1R15A SVEP1 PRR7	1.40e-05	199	60	6	2071_UP
Drug	Cefepime hydrochloride [123171-59-5]; Down 200; 7.4uM; PC3; HT_HG-U133A	RARG TNS2 PPP1R15A UTY SVEP1 PRR7	1.44e-05	200	60	6	5761_DN
Disease	C3 glomerulopathy	CFH CFHR5	1.17e-04	9	54	2	C4087273
Disease	hemopexin measurement	CFH CFHR5	1.79e-04	11	54	2	EFO_0008149
Disease	T-cell surface glycoprotein CD3 epsilon chain measurement	SELP CFH	2.53e-04	13	54	2	EFO_0802114
Disease	coagulation factor measurement	CFH CFHR5	6.12e-04	20	54	2	EFO_0004634
Disease	nephrosis (biomarker_via_orthology)	CFH NES	7.42e-04	22	54	2	DOID:2527 (biomarker_via_orthology)
Disease	ceramide measurement	STARD13 PRKCQ ARL15 PREPL	9.08e-04	235	54	4	EFO_0010222
Disease	eosinophil measurement	SPAM1 ARSB PELP1	1.03e-03	108	54	3	EFO_0803540
Disease	L-Selectin measurement	SELP C2CD4B	1.48e-03	31	54	2	EFO_0008202
Disease	rheumatoid arthritis	GPR137 NUP88 KCP PRKCQ ARL15	1.55e-03	462	54	5	EFO_0000685
Disease	eyelid sagging measurement	ARSB ADAMTS18	1.57e-03	32	54	2	EFO_0009360
Disease	level of Sphingomyelin (d40:1) in blood serum	PELP1 NUP88	1.57e-03	32	54	2	OBA_2045182
Disease	celiac disease	PUS10 PPP1R12B PRKCQ	1.61e-03	126	54	3	EFO_0001060
Disease	Complement deficiency disease	CFH CFHR5	1.67e-03	33	54	2	C0272242
Disease	sphingomyelin measurement	PELP1 PPP1R12B NUP88 GALNT6	1.68e-03	278	54	4	EFO_0010118
Disease	primary dental caries	CFH ADAMTS18	1.78e-03	34	54	2	EFO_0600095

Protein segments in the cluster

Peptide	Gene	Start	Entry
QPKRIFFGPVPCPTC	PRAMEF33	446	A0A0G2JMD5
LCCKGPPPARPEYDL	ARL15	21	Q9NXU5
KTLAPPPEALDCPAC	CCIN	561	Q13939
PAPRCTLKPCDYPDI	CFH	316	P08603
VPAKQCPPLCTRFLP	APEX2	316	Q9UBZ4
PPVLRACNTNFCPAP	ADAMTS18	1166	Q8TE60
PPPPRVYKPCFVCND	RARG	81	P13631
GKRLPCPPNCPDEVY	JAK1	1111	P23458
PEFRPSPAPCLLQCP	DGKK	171	Q5KSL6
PCSIKNEARPPCLPT	PRKCQ	321	Q04759
QPKRIFFGPIPCPSC	PRAMEF17	446	Q5VTA0
CLPKTPRCAPEPDAF	LHCGR	336	P22888
LPLQRPPFCPFAALE	NUDT17	61	P0C025
HLQCPRSPRKPVCPI	IHO1	501	Q8IYA8
SSQPLLRCEIPCPLP	KIAA0087	6	Q14695
PHPRPLCQVCLPLLA	GPR137	376	Q96N19
IRFPPCCYKKLLSPP	HECTD2	521	Q5U5R9
PEFCIPPRLPAPCTL	C2CD4B	31	A6NLJ0
CPPPDFFRPCRLLPT	NOL6	256	Q9H6R4
RLLTQCRPPCPFTPK	PLK5	101	Q496M5
LNAQAACAPRCPAPP	NES	151	P48681
SPRCPPPLACALQAF	PELP1	591	Q8IZL8
RPAPPCPALCLQADR	PRR7	221	Q8TB68
PCPPNSPKAVCAVLE	PUS10	266	Q3MIT2
TPCALPQALPQARPC	CEMP1	96	Q6PRD7
LCKEITCPPPPVIYN	CR2	521	P20023
CPRCPDSLPPVNNKV	CHRDL1	96	Q9BU40
CLAGPPAPARACQLP	CCDC3	11	Q9BQI4
PDCPFPRRVKLPGKC	CCN2	146	P29279
PECIEQKFKRCPPLP	GALNT3	171	Q14435
RPPECVDQKFRRCPP	GALNT6	161	Q8NCL4
PPTLCCLKLAFIDPA	BRWD1	1016	Q9NSI6
CTEKREQFCPPPPQI	CFHR5	381	Q9BXR6
QCLAAQCPPLKIPER	SELP	256	P16109
PCQPSCVPLDEKLLP	ARSB	116	P15848
LGLLRAQPFPCPPAC	GP5	11	P40197
RPCCPLLRKFPVLPV	LINC02913	201	Q8NAJ2
PCCLTLNFRAPPVIP	SPAM1	31	P38567
RALQNCCSVPSPLPP	PPP1R18	391	Q6NYC8
PGRLDKCVYCPPPDQ	PEX1	996	O43933
AECPPCIPPPSAFLK	PPP1R15A	326	O75807
SPCLRNCIMPPRFPK	PCARE	756	A6NGG8
HILCTKPLPCRQPAP	NUP88	451	Q99567
LKNCFRPPPPCIALE	RTL1	531	A6NKG5
SNSCILLDKCPPPRP	UTY	856	O14607
LQNSPPPACRKGLPC	STARD13	311	Q9Y3M8
SPLCPLCRLPFDPKK	RNF166	66	Q96A37
PKACAPALCPFPARG	KCP	761	Q6ZWJ8
PAQRLCQPVLPSPAC	PMEL	536	P40967
IPLCKPVNCGPPEDL	SVEP1	2941	Q4LDE5
PQIPECPICGKPFLT	SLX4	331	Q8IY92
PLPCCFRRLSDPLLP	SSH1	506	Q8WYL5
QALPCPPACRHPEKQ	C15orf39	281	Q6ZRI6
PKERCPPNLAPLCVS	UHRF1BP1L	1086	A0JNW5
RGPPLQKNCPDPELC	ZNF174	31	Q15697
CLALPPLAEPVCPER	TRIL	16	Q7L0X0
QPKRIFFGPVPCPNC	PRAMEF10	446	O60809
PKNCPFQLCSPIRPP	PREPL	401	Q4J6C6
QCVPPIPIRPCVLKY	TRRAP	2681	Q9Y4A5
PISLPCCLRIPSKDP	TNS2	1236	Q63HR2
PCSERQLIKPVPFCP	ZNF518B	801	Q9C0D4
PICHRLRCPAQPDKP	PPP1R12B	716	O60237