Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	NUT	NUTM2F NUTM2G	9.10e-05	5	57	2	IPR024310
Domain	NUT_N	NUTM2F NUTM2G	9.10e-05	5	57	2	IPR024309
Domain	NUT	NUTM2F NUTM2G	9.10e-05	5	57	2	PF12881
Pubmed	Special AT-rich sequence-binding protein 2 (Satb2) synergizes with Bmp9 and is essential for osteo/odontogenic differentiation of mouse incisor mesenchymal stem cells.	SATB2 GDF2	3.03e-06	2	61	2	33660290
Pubmed	Genetic mutations in SPINK1, CFTR, CTRC genes in acute pancreatitis.	CFTR CTRC	9.07e-06	3	61	2	26100556
Pubmed	CFTR, SPINK1, PRSS1, and CTRC mutations are not associated with pancreatic cancer in German patients.	CFTR CTRC	1.81e-05	4	61	2	25003218
Pubmed	PRSS1, SPINK1, CFTR, and CTRC Pathogenic Variants in Korean Patients With Idiopathic Pancreatitis.	CFTR CTRC	1.81e-05	4	61	2	27578509
Pubmed	A conservative assessment of the major genetic causes of idiopathic chronic pancreatitis: data from a comprehensive analysis of PRSS1, SPINK1, CTRC and CFTR genes in 253 young French patients.	CFTR CTRC	1.81e-05	4	61	2	23951356
Pubmed	Genetic and electrophysiological characteristics of recurrent acute pancreatitis.	CFTR CTRC	1.81e-05	4	61	2	25383785
Pubmed	CFTR, SPINK1, CTRC and PRSS1 variants in chronic pancreatitis: is the role of mutated CFTR overestimated?	CFTR CTRC	1.81e-05	4	61	2	22427236
Pubmed	PRSS1-Related Hereditary Pancreatitis	CFTR CTRC	3.02e-05	5	61	2	22379635
Pubmed	TRAF7 potentiates MEKK3-induced AP1 and CHOP activation and induces apoptosis.	MAP3K14 MAP3K2	8.42e-05	8	61	2	15001576
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SYNRG SSH1 EIF4G1 DISP2 CEP192 ANKHD1 ALKBH6 CLDN23 CREB3	1.26e-04	1105	61	9	35748872
Pubmed	Microsatellite scan identifies new candidate genes for susceptibility to alcoholic chronic pancreatitis in Japanese patients.	CFTR CTRC	1.65e-04	11	61	2	19096130
Pubmed	Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.	PKD1L2 SLC25A25 SLITRK1	1.89e-04	63	61	3	11572484
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KNTC1 SSH1 GNPTAB ZNF347 SLITRK1 SH2B1	2.26e-04	493	61	6	15368895
Pubmed	CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion.	CEP192 CEP97	2.72e-04	14	61	2	32060285
Pubmed	MAP3Ks as central regulators of cell fate during development.	MAP3K14 MAP3K2	3.13e-04	15	61	2	18855897
Pubmed	Pancreatitis Overview	CFTR CTRC	3.13e-04	15	61	2	24624459
Pubmed	Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors.	CFTR EYA2	4.05e-04	17	61	2	30838872
Pubmed	Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R.	SATB2 EIF4G1	8.15e-04	24	61	2	25157170
Pubmed	Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SLC8A2 SATB2 ANKHD1	8.24e-04	104	61	3	10470851
Pubmed	Protein translation rate determines neocortical neuron fate.	SATB2 EIF4G1	1.03e-03	27	61	2	38849354
Pubmed	Spatial centrosome proteome of human neural cells uncovers disease-relevant heterogeneity.	CEP192 CEP97	1.03e-03	27	61	2	35709258
Pubmed	The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.	SYNRG SATB2 CEP192	1.40e-03	125	61	3	29467281
Pubmed	GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.	SYNRG GPR179	1.45e-03	32	61	2	23535730
Pubmed	Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex.	SATB2 CEP97	1.54e-03	33	61	2	30626697
Pubmed	Expression of the Bcl-2 protein BAD promotes prostate cancer growth.	MAP3K14 MAP3K2	1.64e-03	34	61	2	19593445
Pubmed	Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects.	PKD1L2 BCO1	1.73e-03	35	61	2	19844255
Cytoband	16q23.2	PKD1L2 BCO1	9.48e-05	11	61	2	16q23.2
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Gad2-Inhibitory_Neuron.Gad1Gad2.Gad2-Kcnc3_(GABAergic,_K/Na_Channel_State)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SATB2 FFAR1 CLDN23 BCO1	8.52e-07	53	61	4	e90685a7c6ef223783b1c1a6b1896fd566449422
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Gad2\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SATB2 FFAR1 CLDN23 BCO1	8.52e-07	53	61	4	5ad1a5c5c9a1dc66dd7e6de6edbee0176678966c
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Gad2-Inhibitory_Neuron.Gad1Gad2.Gad2-Kcnc3_(GABAergic,_K/Na_Channel_State)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SATB2 FFAR1 CLDN23 BCO1	8.52e-07	53	61	4	a58b0b1c9991cfebf20e206a129b79f494785138
Disease	carotenoid measurement	PKD1L2 BCO1	3.54e-06	2	56	2	EFO_0004737
Disease	X-23749 measurement	PKD1L2 BCO1	3.54e-06	2	56	2	EFO_0022125
Disease	carotene diol (3) measurement	PKD1L2 BCO1	3.54e-06	2	56	2	EFO_0800172
Disease	carotenoid measurement, beta-carotene measurement	PKD1L2 BCO1	3.54e-06	2	56	2	EFO_0004737, EFO_0007894
Disease	carotenoid measurement, lutein measurement	PKD1L2 BCO1	3.54e-06	2	56	2	EFO_0004737, EFO_0007895
Disease	carotene diol (2) measurement	PKD1L2 BCO1	1.06e-05	3	56	2	EFO_0800171
Disease	carotene diol (1) measurement	PKD1L2 BCO1	1.06e-05	3	56	2	EFO_0800170
Disease	Acute recurrent pancreatitis	CFTR CTRC	2.12e-05	4	56	2	C0267937
Disease	Hereditary pancreatitis	CFTR CTRC	3.52e-05	5	56	2	cv:C0238339
Disease	PANCREATITIS, HEREDITARY	CFTR CTRC	3.52e-05	5	56	2	167800
Disease	Autosomal Dominant Hereditary Pancreatitis	CFTR CTRC	3.52e-05	5	56	2	C4080064
Disease	eye disease (implicated_via_orthology)	RP1L1 EYA2	5.28e-05	6	56	2	DOID:5614 (implicated_via_orthology)
Disease	Hereditary pancreatitis	CFTR CTRC	7.38e-05	7	56	2	C0238339
Disease	arylsulfatase K measurement	GPR150 GNPTAB	9.83e-05	8	56	2	EFO_0801395
Disease	Pancreatitis, Chronic	CFTR CTRC	1.26e-04	9	56	2	C0149521
Disease	esophageal adenocarcinoma, Barrett's esophagus, sex interaction measurement	CFTR RP1L1	2.72e-04	13	56	2	EFO_0000280, EFO_0000478, EFO_0008343
Disease	Hypermetropia	ARHGAP10 DGKA SLITRK1	1.00e-03	103	56	3	HP_0000540
Disease	esophageal adenocarcinoma, Barrett's esophagus	CFTR RP1L1	1.59e-03	31	56	2	EFO_0000280, EFO_0000478

Protein segments in the cluster

Peptide	Gene	Start	Entry
TQLSGRKLQNWGGLP	ALKBH6	51	Q3KRA9
SLLLDQQGLGAWPSK	ADAD2	561	Q8NCV1
WLNVQLSPQQGSLGL	CPN2	501	P22792
LWLLGNTPLQDKGNS	CFTR	881	P13569
QTFSGGSNWPLRGRK	ARSI	301	Q5FYB1
KSSTGPGEQLRNALW	COMP	641	P49747
QPLGTLGQGGWKLLG	LINC01565	36	O15544
WRLSKSQLPSGGLAQ	DISP2	566	A7MBM2
LAGSLQGKPLQSWGR	GDF2	16	Q9UK05
LIRSPSLAKQSWGGG	LDLRAP1	11	Q5SW96
WLEGTLNGKRGLIPQ	ARHGAP10	766	A1A4S6
QAKSPGELLRWLGQN	FASTK	91	Q14296
VARGGNPLATLQWLK	NPHS1	266	O60500
SGLLKGNSRQTVWRG	GNPTAB	196	Q3T906
GWQELPKAGLQSLGS	GPR179	1221	Q6PRD1
LGAWQLGNPGSRSQK	PRSS22	106	Q9GZN4
LGNPGSRSQKVGVAW	PRSS22	111	Q9GZN4
RNPNLKTLLSVGGWN	CHI3L1	86	P36222
NLSWNSKVGGNLPLI	LRRC31	176	Q6UY01
RAPTNWRLGKLLGQG	MAP3K2	351	Q9Y2U5
VNPKSGGKQGQRVLW	DGKA	381	P23743
LWIGLNKRSPDLQGS	LY75	711	O60449
QWGIRLGKLGISFQP	KNTC1	1406	P50748
LQTLKGGLGVQPGTW	PKD1L2	1786	Q7Z442
GRLWTNGPIADKLQQ	CTRC	161	Q99895
PNLGGSWRKLGLITG	FFAR1	251	O14842
GSNPKIRRNKIWGGQ	FBXO11	671	Q86XK2
WSNLTHPGNKINLLG	FSTL3	71	O95633
SVVNWSGQGLQKLGP	CEP97	16	Q8IW35
QGFIGWRSAVPGLNK	C20orf85	96	Q9H1P6
NNQLFAPGGRLSWGK	EIF4G1	1081	Q04637
LSNKQFLAWGGVPLG	CEP192	1766	Q8TEP8
LLLTDKGQQAGWPGA	KLF11	241	O14901
NILRIGIQNLGSPLW	ELP4	251	Q96EB1
KSWAQNPGLPGILNT	CCDC201	131	A0A1B0GTI1
QANLTRKGGWLPTGS	CREB3	346	O43889
NLTGTLAPGWRLVKG	CLDN23	21	Q96B33
PTLAGQTLKGPWNNL	PARP10	806	Q53GL7
VNRALQQVGGLKSPW	MAP3K14	651	Q99558
NNVGGLIGTPKRETW	EYA2	396	O00167
LTWGLGGPSQSQKRK	NUTM2D	776	Q5VT03
LAWGLGGPSQSQKRK	NUTM2F	726	A1L443
LAWGLGGPSQSQKRK	NUTM2G	711	Q5VZR2
GGGQPQWQKCRLLLR	SH2B1	281	Q9NRF2
GQIWALANRTTPGKL	SYNRG	336	Q9UMZ2
QLGGLKLDTPSKGWQ	TOGARAM2	71	Q6ZUX3
LLGWGLNLTLGQGAP	GPR150	21	Q8NGU9
AAQAQGIIKLGRWNP	SATB2	111	Q9UPW6
LAWINTPRKNGGLGH	PRDX3	141	P30048
QQPKVRGWLLASLDG	PEX13	306	Q92968
GPNGVWTLLQKGRSV	SIRT7	121	Q9NRC8
LGAGRWGQLPTQLDQ	SSH1	596	Q8WYL5
TGKIPAWLQGTLLRN	BCO1	21	Q9HAY6
RNKKGNTPLWLASNG	ANKHD1	1321	Q8IWZ3
SLWRGNGINVLKIAP	SLC25A25	241	Q6KCM7
NGGTKIPGNWQIKIR	SLITRK1	306	Q96PX8
LSGLTSRNKNGSWGP	RP1L1	241	Q8IWN7
GKQGNVLPLWGNEKT	PRPF38B	41	Q5VTL8
GIRSQPQGCLGKWRS	WASH4P	16	A8MWX3
LPTGQQGGTRKLWEI	TMEM131	256	Q92545
LLLTQGQKANNWGSP	ZNF347	246	Q96SE7
LWIGPNEKTLTGNNR	ZPBP2	71	Q6X784
LGQPQWLKRGISALL	SLC8A2	611	Q9UPR5