Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	molecular adaptor activity	SHANK1 NSD1 SEPTIN11 TLE7 KDM5B SHANK2 SEPTIN10 ZBED1 KDM5A TRIM22 NOTCH1 ITSN2	5.78e-07	1356	32	12	GO:0060090
GeneOntologyMolecularFunction	synaptic receptor adaptor activity	SHANK1 SHANK2	1.49e-05	4	32	2	GO:0030160
GeneOntologyMolecularFunction	transcription coregulator activity	NSD1 TLE7 KDM5B ZBED1 KDM5A TRIM22 NOTCH1	2.46e-05	562	32	7	GO:0003712
GeneOntologyMolecularFunction	histone H3K4me/H3K4me2/H3K4me3 demethylase activity	KDM5B KDM5A	3.72e-05	6	32	2	GO:0034647
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	SHANK1 NSD1 TLE7 KDM5B SHANK2 ZBED1 KDM5A TRIM22 NOTCH1	6.07e-05	1160	32	9	GO:0030674
GeneOntologyMolecularFunction	histone H3K4 demethylase activity	KDM5B KDM5A	6.92e-05	8	32	2	GO:0032453
GeneOntologyMolecularFunction	structural constituent of postsynaptic density	SHANK1 SHANK2	1.36e-04	11	32	2	GO:0098919
GeneOntologyMolecularFunction	structural constituent of postsynaptic specialization	SHANK1 SHANK2	1.92e-04	13	32	2	GO:0098879
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH12 DYNC2H1	3.75e-04	18	32	2	GO:0008569
GeneOntologyMolecularFunction	transcription corepressor activity	NSD1 TLE7 KDM5B TRIM22	4.71e-04	229	32	4	GO:0003714
GeneOntologyMolecularFunction	histone H3 demethylase activity	KDM5B KDM5A	9.16e-04	28	32	2	GO:0141052
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH12 DYNC2H1	9.16e-04	28	32	2	GO:0051959
GeneOntologyMolecularFunction	histone demethylase activity	KDM5B KDM5A	1.12e-03	31	32	2	GO:0032452
GeneOntologyMolecularFunction	structural constituent of postsynapse	SHANK1 SHANK2	1.20e-03	32	32	2	GO:0099186
GeneOntologyMolecularFunction	protein demethylase activity	KDM5B KDM5A	1.20e-03	32	32	2	GO:0140457
GeneOntologyMolecularFunction	transcription coactivator activity	ZBED1 KDM5A TRIM22 NOTCH1	1.34e-03	303	32	4	GO:0003713
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH12 DYNC2H1	1.60e-03	37	32	2	GO:0045505
GeneOntologyMolecularFunction	structural constituent of synapse	SHANK1 SHANK2	2.06e-03	42	32	2	GO:0098918
GeneOntologyMolecularFunction	demethylase activity	KDM5B KDM5A	2.26e-03	44	32	2	GO:0032451
GeneOntologyMolecularFunction	ionotropic glutamate receptor binding	SHANK1 SHANK2	3.14e-03	52	32	2	GO:0035255
GeneOntologyMolecularFunction	signaling receptor complex adaptor activity	SHANK1 SHANK2	3.38e-03	54	32	2	GO:0030159
GeneOntologyMolecularFunction	2-oxoglutarate-dependent dioxygenase activity	KDM5B KDM5A	4.86e-03	65	32	2	GO:0016706
GeneOntologyMolecularFunction	microtubule motor activity	DNAH12 DYNC2H1	5.61e-03	70	32	2	GO:0003777
GeneOntologyMolecularFunction	histone modifying activity	NSD1 KDM5B KDM5A	5.78e-03	229	32	3	GO:0140993
GeneOntologyCellularComponent	postsynaptic specialization	SHANK1 SEPTIN11 USP6 SHANK2 NOTCH1 FABP5	1.00e-04	503	32	6	GO:0099572
GeneOntologyCellularComponent	neuron to neuron synapse	SHANK1 SEPTIN11 USP6 SHANK2 NOTCH1 FABP5	1.24e-04	523	32	6	GO:0098984
GeneOntologyCellularComponent	glutamatergic synapse	SHANK1 SEPTIN11 USP6 SHANK2 ACAN NOTCH1 FABP5	1.94e-04	817	32	7	GO:0098978
GeneOntologyCellularComponent	septin complex	SEPTIN11 SEPTIN10	2.04e-04	14	32	2	GO:0031105
GeneOntologyCellularComponent	septin ring	SEPTIN11 SEPTIN10	2.04e-04	14	32	2	GO:0005940
GeneOntologyCellularComponent	septin cytoskeleton	SEPTIN11 SEPTIN10	2.69e-04	16	32	2	GO:0032156
GeneOntologyCellularComponent	postsynaptic density	SHANK1 USP6 SHANK2 NOTCH1 FABP5	5.69e-04	451	32	5	GO:0014069
GeneOntologyCellularComponent	asymmetric synapse	SHANK1 USP6 SHANK2 NOTCH1 FABP5	7.33e-04	477	32	5	GO:0032279
GeneOntologyCellularComponent	postsynapse	SHANK1 SEPTIN11 USP6 SLC6A11 SHANK2 NOTCH1 FABP5	7.34e-04	1018	32	7	GO:0098794
GeneOntologyCellularComponent	Schaffer collateral - CA1 synapse	SHANK1 MAPK9 NOTCH1	1.69e-03	155	32	3	GO:0098685
GeneOntologyCellularComponent	synaptic membrane	SHANK1 SLC6A11 SHANK2 NOTCH1 ITSN2	1.79e-03	583	32	5	GO:0097060
GeneOntologyCellularComponent	GABA-ergic synapse	SEPTIN11 SLC6A11 ACAN	1.99e-03	164	32	3	GO:0098982
GeneOntologyCellularComponent	postsynaptic density, intracellular component	USP6 FABP5	2.55e-03	49	32	2	GO:0099092
GeneOntologyCellularComponent	dynein complex	DNAH12 DYNC2H1	3.09e-03	54	32	2	GO:0030286
GeneOntologyCellularComponent	postsynaptic membrane	SHANK1 SLC6A11 SHANK2 NOTCH1	3.25e-03	405	32	4	GO:0045211
GeneOntologyCellularComponent	postsynaptic specialization, intracellular component	USP6 FABP5	3.32e-03	56	32	2	GO:0099091
GeneOntologyCellularComponent	9+2 motile cilium	DNAH12 SEPTIN10 DYNC2H1	5.67e-03	238	32	3	GO:0097729
GeneOntologyCellularComponent	dendritic spine	SHANK1 SEPTIN11 SHANK2	5.93e-03	242	32	3	GO:0043197
GeneOntologyCellularComponent	neuron spine	SHANK1 SEPTIN11 SHANK2	6.28e-03	247	32	3	GO:0044309
GeneOntologyCellularComponent	cell division site	SEPTIN11 SEPTIN10	6.66e-03	80	32	2	GO:0032153
Domain	Zinc_finger_PHD-type_CS	NSD1 KDM5B TCF19 KDM5A	3.42e-06	65	30	4	IPR019786
Domain	PHD	NSD1 KDM5B TCF19 KDM5A	6.07e-06	75	30	4	PF00628
Domain	Znf_PHD-finger	NSD1 KDM5B TCF19 KDM5A	7.47e-06	79	30	4	IPR019787
Domain	PHD	NSD1 KDM5B TCF19 KDM5A	1.20e-05	89	30	4	SM00249
Domain	Znf_PHD	NSD1 KDM5B TCF19 KDM5A	1.31e-05	91	30	4	IPR001965
Domain	Lys_sp_deMease-like_dom	KDM5B KDM5A	1.49e-05	4	30	2	IPR013637
Domain	PLU-1	KDM5B KDM5A	1.49e-05	4	30	2	PF08429
Domain	ZF_PHD_2	NSD1 KDM5B TCF19 KDM5A	1.56e-05	95	30	4	PS50016
Domain	ZF_PHD_1	NSD1 KDM5B TCF19 KDM5A	1.62e-05	96	30	4	PS01359
Domain	zf-C5HC2	KDM5B KDM5A	2.49e-05	5	30	2	PF02928
Domain	Znf_C5HC2	KDM5B KDM5A	2.49e-05	5	30	2	IPR004198
Domain	Znf_FYVE_PHD	NSD1 KDM5B TCF19 KDM5A	8.61e-05	147	30	4	IPR011011
Domain	JmjN	KDM5B KDM5A	1.11e-04	10	30	2	PF02375
Domain	JmjN	KDM5B KDM5A	1.11e-04	10	30	2	SM00545
Domain	JMJN	KDM5B KDM5A	1.11e-04	10	30	2	PS51183
Domain	JmjN	KDM5B KDM5A	1.11e-04	10	30	2	IPR003349
Domain	Septin	SEPTIN11 SEPTIN10	1.92e-04	13	30	2	PF00735
Domain	G_SEPTIN_dom	SEPTIN11 SEPTIN10	1.92e-04	13	30	2	IPR030379
Domain	G_SEPTIN	SEPTIN11 SEPTIN10	1.92e-04	13	30	2	PS51719
Domain	ATPase_dyneun-rel_AAA	DNAH12 DYNC2H1	2.24e-04	14	30	2	IPR011704
Domain	Dynein_heavy_chain_D4_dom	DNAH12 DYNC2H1	2.24e-04	14	30	2	IPR024317
Domain	Septin	SEPTIN11 SEPTIN10	2.24e-04	14	30	2	IPR016491
Domain	Dynein_heavy_dom-2	DNAH12 DYNC2H1	2.24e-04	14	30	2	IPR013602
Domain	DHC_N2	DNAH12 DYNC2H1	2.24e-04	14	30	2	PF08393
Domain	AAA_8	DNAH12 DYNC2H1	2.24e-04	14	30	2	PF12780
Domain	AAA_5	DNAH12 DYNC2H1	2.24e-04	14	30	2	PF07728
Domain	DHC_fam	DNAH12 DYNC2H1	2.59e-04	15	30	2	IPR026983
Domain	-	KDM5B KDM5A	2.59e-04	15	30	2	1.10.150.60
Domain	ARID	KDM5B KDM5A	2.59e-04	15	30	2	PF01388
Domain	Dynein_heavy_dom	DNAH12 DYNC2H1	2.59e-04	15	30	2	IPR004273
Domain	BRIGHT	KDM5B KDM5A	2.59e-04	15	30	2	SM00501
Domain	ARID_dom	KDM5B KDM5A	2.59e-04	15	30	2	IPR001606
Domain	ARID	KDM5B KDM5A	2.59e-04	15	30	2	PS51011
Domain	Dynein_heavy	DNAH12 DYNC2H1	2.59e-04	15	30	2	PF03028
Domain	SH3_2	SHANK1 SHANK2 ITSN2	3.50e-04	86	30	3	IPR011511
Domain	SH3_2	SHANK1 SHANK2 ITSN2	3.50e-04	86	30	3	PF07653
Domain	JmjC	KDM5B KDM5A	6.73e-04	24	30	2	PF02373
Domain	-	NSD1 KDM5B TCF19 KDM5A TRIM22	6.81e-04	449	30	5	3.30.40.10
Domain	Znf_RING/FYVE/PHD	NSD1 KDM5B TCF19 KDM5A TRIM22	7.52e-04	459	30	5	IPR013083
Domain	-	SEPTIN11 DNAH12 AGAP9 SEPTIN10 DYNC2H1 NOD2	1.04e-03	746	30	6	3.40.50.300
Domain	JMJC	KDM5B KDM5A	1.20e-03	32	30	2	PS51184
Domain	JmjC_dom	KDM5B KDM5A	1.20e-03	32	30	2	IPR003347
Domain	JmjC	KDM5B KDM5A	1.28e-03	33	30	2	SM00558
Domain	P-loop_NTPase	SEPTIN11 DNAH12 AGAP9 SEPTIN10 DYNC2H1 NOD2	2.00e-03	848	30	6	IPR027417
Domain	ZF_C3H1	ZFC3H1 PARP12	3.90e-03	58	30	2	PS50103
Domain	SH3	SHANK1 SHANK2 ITSN2	4.92e-03	216	30	3	PS50002
Domain	SH3	SHANK1 SHANK2 ITSN2	4.92e-03	216	30	3	SM00326
Domain	SH3_domain	SHANK1 SHANK2 ITSN2	5.18e-03	220	30	3	IPR001452
Domain	SAM_1	SHANK1 SHANK2	5.32e-03	68	30	2	PF00536
Domain	RNaseH-like_dom	ZBED1 POLG	5.47e-03	69	30	2	IPR012337
Domain	-	SHANK1 AGAP9 NOTCH1	7.21e-03	248	30	3	1.25.40.20
Domain	Ankyrin_rpt-contain_dom	SHANK1 AGAP9 NOTCH1	7.70e-03	254	30	3	IPR020683
Domain	ANK_REP_REGION	SHANK1 AGAP9 NOTCH1	7.70e-03	254	30	3	PS50297
Pubmed	Variants in TRIM22 That Affect NOD2 Signaling Are Associated With Very-Early-Onset Inflammatory Bowel Disease.	TRIM22 NOD2	8.20e-07	2	32	2	26836588
Pubmed	KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.	KDM5B KDM5A	8.20e-07	2	32	2	30472020
Pubmed	KDM5A and KDM5B histone-demethylases contribute to HU-induced replication stress response and tolerance.	KDM5B KDM5A	8.20e-07	2	32	2	34184733
Pubmed	Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: a gradient of severity in cognitive impairments.	SHANK1 SHANK2	8.20e-07	2	32	2	25188300
Pubmed	TRIM22 inhibits endometrial cancer progression through the NOD2/NF‑κB signaling pathway and confers a favorable prognosis.	TRIM22 NOD2	8.20e-07	2	32	2	32319602
Pubmed	Drawing a line between histone demethylase KDM5A and KDM5B: their roles in development and tumorigenesis.	KDM5B KDM5A	8.20e-07	2	32	2	36509829
Pubmed	KDM5 lysine demethylases are involved in maintenance of 3'UTR length.	KDM5B KDM5A	8.20e-07	2	32	2	28138513
Pubmed	The Shank family of scaffold proteins.	SHANK1 SHANK2	2.46e-06	3	32	2	10806096
Pubmed	Dynamin isoform-specific interaction with the shank/ProSAP scaffolding proteins of the postsynaptic density and actin cytoskeleton.	SHANK1 SHANK2	2.46e-06	3	32	2	11583995
Pubmed	JNK1 Induces Notch1 Expression to Regulate Genes Governing Photoreceptor Production.	MAPK9 NOTCH1	2.46e-06	3	32	2	31450635
Pubmed	Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin.	SHANK1 SHANK2	2.46e-06	3	32	2	10433268
Pubmed	Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins.	SHANK1 SHANK2	2.46e-06	3	32	2	10433269
Pubmed	Translational neurobiology in Shank mutant mice--model systems for neuropsychiatric disorders.	SHANK1 SHANK2	2.46e-06	3	32	2	25917711
Pubmed	A dual role for NOTCH signaling in joint cartilage maintenance and osteoarthritis.	ACAN NOTCH1	2.46e-06	3	32	2	26198357
Pubmed	Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases.	KDM5B KDM5A	2.46e-06	3	32	2	26645689
Pubmed	Modeling autism by SHANK gene mutations in mice.	SHANK1 SHANK2	2.46e-06	3	32	2	23583105
Pubmed	Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles.	DNAH12 DYNC2H1	2.46e-06	3	32	2	8666668
Pubmed	Histone demethylase KDM5 regulates cardiomyocyte maturation by promoting fatty acid oxidation, oxidative phosphorylation, and myofibrillar organization.	KDM5B KDM5A	2.46e-06	3	32	2	38230606
Pubmed	Re-expression of the retinoblastoma-binding protein 2-homolog 1 reveals tumor-suppressive functions in highly metastatic melanoma cells.	KDM5B KDM5A	2.46e-06	3	32	2	16645588
Pubmed	Dynamic Change of Shanks Gene mRNA Expression and DNA Methylation in Epileptic Rat Model and Human Patients.	SHANK1 SHANK2	2.46e-06	3	32	2	32564287
Pubmed	Intracellular pathogen sensor NOD2 programs macrophages to trigger Notch1 activation.	NOTCH1 NOD2	2.46e-06	3	32	2	21156799
Pubmed	Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.	NSD1 KDM5B KDM5A	3.79e-06	33	32	3	26864203
Pubmed	Novel JARID1C/SMCX mutations in patients with X-linked mental retardation.	KDM5B KDM5A	4.92e-06	4	32	2	16541399
Pubmed	SHANK3 gene mutations associated with autism facilitate ligand binding to the Shank3 ankyrin repeat region.	SHANK1 SHANK2	4.92e-06	4	32	2	23897824
Pubmed	MiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network.	KDM5A NOTCH1	4.92e-06	4	32	2	27453008
Pubmed	The Shank family of postsynaptic density proteins interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42.	SHANK1 SHANK2	4.92e-06	4	32	2	12626503
Pubmed	H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence.	KDM5B KDM5A	4.92e-06	4	32	2	22615382
Pubmed	Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor.	SHANK1 SHANK2	8.19e-06	5	32	2	16606358
Pubmed	The insulin receptor substrate IRSp53 links postsynaptic shank1 to the small G-protein cdc42.	SHANK1 SHANK2	8.19e-06	5	32	2	12504591
Pubmed	Identification of proteins interacting with the rat somatostatin receptor subtype 2.	SHANK1 SHANK2	8.19e-06	5	32	2	11087996
Pubmed	Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock.	KDM5B KDM5A	1.23e-05	6	32	2	21960634
Pubmed	The calcium-independent receptor for alpha-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/Shank family of multidomain proteins.	SHANK1 SHANK2	1.23e-05	6	32	2	10964907
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	NSD1 KDM5B KDM5A	1.27e-05	49	32	3	34368113
Pubmed	Direct interaction of GluRdelta2 with Shank scaffold proteins in cerebellar Purkinje cells.	SHANK1 SHANK2	1.72e-05	7	32	2	15207857
Pubmed	DNA-binding properties of ARID family proteins.	KDM5B KDM5A	1.72e-05	7	32	2	15640446
Pubmed	New nomenclature for chromatin-modifying enzymes.	NSD1 KDM5B KDM5A	2.00e-05	57	32	3	18022353
Pubmed	The G protein-coupled receptor CL1 interacts directly with proteins of the Shank family.	SHANK1 SHANK2	2.29e-05	8	32	2	10958799
Pubmed	Sex Hormones Regulate SHANK Expression.	SHANK1 SHANK2	2.29e-05	8	32	2	30319350
Pubmed	Behavioral phenotypes of genetic mouse models of autism.	SHANK1 SHANK2	4.49e-05	11	32	2	26403076
Pubmed	Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.	KDM5B KDM5A	6.36e-05	13	32	2	24619213
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH12 DYNC2H1	7.41e-05	14	32	2	9373155
Pubmed	Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses.	SHANK1 SHANK2	7.41e-05	14	32	2	21795692
Pubmed	PDZ-Containing Proteins Targeted by the ACE2 Receptor.	SHANK1 SHANK2	8.55e-05	15	32	2	34835087
Pubmed	Extracellular Matrix Disorganization Caused by ADAMTS16 Deficiency Leads to Bicuspid Aortic Valve With Raphe Formation.	ACAN NOTCH1	8.55e-05	15	32	2	38018454
Pubmed	Localization of septin proteins in the mouse cochlea.	SEPTIN11 SEPTIN10	9.76e-05	16	32	2	22575789
Pubmed	Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders.	SHANK1 DYNC2H1	1.24e-04	18	32	2	27984743
Pubmed	Androglobin, a chimeric mammalian globin, is required for male fertility.	SEPTIN11 SEPTIN10	1.39e-04	19	32	2	35700329
Pubmed	RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development.	ACAN NOTCH1	1.39e-04	19	32	2	20335360
Pubmed	The histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3.	KDM5B KDM5A	1.54e-04	20	32	2	23637629
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KDM5B KDM5A	1.70e-04	21	32	2	27626377
Pubmed	Ets1 is required for proper migration and differentiation of the cardiac neural crest.	ACAN NOTCH1	1.87e-04	22	32	2	20356956
Pubmed	Netrin 1 directs vascular patterning and maturity in the developing kidney.	UNC5B NOTCH1	2.05e-04	23	32	2	37818607
Pubmed	Molecular reclassification of Crohn's disease by cluster analysis of genetic variants.	DNAH12 NOD2	2.05e-04	23	32	2	20886065
Pubmed	The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.	SEPTIN11 SEPTIN10 ITSN2	2.08e-04	125	32	3	29467281
Pubmed	Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes.	MAPK9 NOTCH1	2.24e-04	24	32	2	22854957
Pubmed	Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development.	ACAN NOTCH1	2.63e-04	26	32	2	19590010
Pubmed	Tbx20 acts upstream of Wnt signaling to regulate endocardial cushion formation and valve remodeling during mouse cardiogenesis.	ACAN NOTCH1	2.84e-04	27	32	2	23824573
Pubmed	Genetic risk profiling and prediction of disease course in Crohn's disease patients.	DNAH12 NOD2	3.05e-04	28	32	2	19422935
Pubmed	The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity.	SHANK1 SHANK2	3.28e-04	29	32	2	19208628
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	NSD1 SEPTIN11 ZFC3H1 SHANK2 KDM5A WDR43 ITSN2	3.52e-04	1497	32	7	31527615
Pubmed	Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development.	SHANK1 DYNC2H1	3.75e-04	31	32	2	25838543
Pubmed	Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice.	NOTCH1 ITSN2	3.75e-04	31	32	2	19666558
Pubmed	A SOX17-PDGFB signaling axis regulates aortic root development.	NOTCH1 FABP5	4.52e-04	34	32	2	35831318
Pubmed	β-Catenin regulates endocardial cushion growth by suppressing p21.	ACAN NOTCH1	4.79e-04	35	32	2	37385754
Pubmed	Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.	NSD1 ACAN	4.79e-04	35	32	2	19389355
Pubmed	Single-cell transcriptomic analysis of mouse neocortical development.	SLC6A11 DNAH12 TCF19	5.13e-04	170	32	3	30635555
Pubmed	Myocardial β-Catenin-BMP2 signaling promotes mesenchymal cell proliferation during endocardial cushion formation.	ACAN NOTCH1	5.65e-04	38	32	2	30201295
Pubmed	Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation.	ACAN NOTCH1	5.65e-04	38	32	2	29743679
Pubmed	A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.	KDM5B CARS2 NOTCH1	6.05e-04	180	32	3	24104479
Pubmed	RONIN Is an Essential Transcriptional Regulator of Genes Required for Mitochondrial Function in the Developing Retina.	NOTCH1 POLG	6.90e-04	42	32	2	26876175
Pubmed	Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.	KDM5B KDM5A	7.57e-04	44	32	2	24183668
Pubmed	Multiple mouse chromosomal loci for dynein-based motility.	DNAH12 DYNC2H1	8.64e-04	47	32	2	8812413
Cytoband	5q35	NSD1 MAPK9	1.18e-04	23	32	2	5q35
GeneFamily	PHD finger proteins	NSD1 KDM5B TCF19 KDM5A	1.07e-05	90	28	4	88
GeneFamily	Septins	SEPTIN11 SEPTIN10	1.79e-04	13	28	2	732
GeneFamily	AT-rich interaction domain containing	KDM5B KDM5A	2.40e-04	15	28	2	418
GeneFamily	Ankyrin repeat domain containing	SHANK1 AGAP9 SHANK2 NOTCH1	4.98e-04	242	28	4	403
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM5B KDM5A	6.25e-04	24	28	2	485
GeneFamily	Sterile alpha motif domain containing	SHANK1 SHANK2	8.15e-03	88	28	2	760
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SHANK1 SEPTIN11 DYNC2H1 ACAN	1.21e-05	199	32	4	abd6117f8a3d7e798d8471c16d97b34aaf50fc9c
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TCF19 CARS2 WDR43	1.99e-04	159	32	3	f7bccfeffa737f151417bf52ea45111b0957bce9
ToppCell	facs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAO NOTCH1 FABP5	2.34e-04	168	32	3	06dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCell	facs-Heart-RA-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAO NOTCH1 FABP5	2.34e-04	168	32	3	1002f058a340763e3d8de0bd1f0547a903526ec6
ToppCell	droplet-Marrow-nan-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAPK9 PARP12 NOD2	2.38e-04	169	32	3	5f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCell	T_cells-ISG-high_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	RFX8 TRIM22 PARP12	2.82e-04	179	32	3	af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Mac-Cycling_Myeloid-Mac\|lymph-node_spleen / Manually curated celltypes from each tissue	SEPTIN11 RWDD2A FABP5	2.96e-04	182	32	3	84018a84e1aa52fa52ccfc26db9cd1fb6d535b31
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	UNC5B NOTCH1 FABP5	2.96e-04	182	32	3	0346f81bbb1f309f3e9d063b20547d548d09472c
ToppCell	E12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SEPTIN11 WDR43 FABP5	3.01e-04	183	32	3	523896bd1a93bdda81a009768baa3a1bdbd108b8
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Mac-Macrophage\|lymph-node_spleen / Manually curated celltypes from each tissue	DAO SEPTIN10 FABP5	3.01e-04	183	32	3	0bcbd60e10b9d6898915dab1987fd46dc7238b19
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NSD1 SEPTIN11 ITSN2	3.06e-04	184	32	3	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH12 SHANK2 DYNC2H1	3.11e-04	185	32	3	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEPTIN11 ACAN FABP5	3.16e-04	186	32	3	db4d9ac89cc1e55062ba888b3410b773340595dd
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-bladder_urothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDM5B NOTCH1 FABP5	3.21e-04	187	32	3	aa336fb568a24e12c0454265ddd71ed10a6614cf
ToppCell	15-Distal-Mesenchymal-Pericyte\|Distal / Age, Tissue, Lineage and Cell class	SEPTIN11 ACAN FABP5	3.26e-04	188	32	3	4963382e54aac06bf5047c7d725393db70667ee7
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-myofibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	DYNC2H1 ACAN UNC5B	3.26e-04	188	32	3	116ca07ee4413dcc0e9e5ac99bfee6ed7b7847c6
ToppCell	T_cells-ISG-high_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	RFX8 TRIM22 PARP12	3.26e-04	188	32	3	6f8946d4710f6e32c937213f99b790b098b8819c
ToppCell	facs-GAT-Fat-24m-Endothelial-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC5B NOTCH1 FABP5	3.36e-04	190	32	3	da2fcd4a2cc6e45c8174109d892f1424e39919a1
ToppCell	facs-GAT-Fat-24m-Endothelial-endothelial_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC5B NOTCH1 FABP5	3.36e-04	190	32	3	e584eaccbc22aa7f7a4340ed8a2a8b45ddca93f4
ToppCell	facs-GAT-Fat-24m-Endothelial\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC5B NOTCH1 FABP5	3.36e-04	190	32	3	3395b2ff6ffadf84cdb1b5a37a5b6be05b56c30f
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NOTCH1 FABP5 NOD2	3.36e-04	190	32	3	bb1476b44dd49e1dd52a636a91c4600b6d4fbe2e
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NOTCH1 FABP5 NOD2	3.36e-04	190	32	3	d180205c70b5ca9bc5a01a2e6cb42fcebc7f630d
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NOTCH1 FABP5 NOD2	3.36e-04	190	32	3	38a815abf0ac5cac6071737cadc54a514f62d37d
ToppCell	facs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NOTCH1 FABP5 NOD2	3.36e-04	190	32	3	2655df8c0883dd811fa7617301f9c4b0a4dd55ec
ToppCell	(02)_Cycling_Basal_(regeneration)\|World / shred by cell type and Timepoint	TCF19 NOTCH1 FABP5	3.36e-04	190	32	3	53f017a11ca5ebe9025558e12cedc409cab2e5aa
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	DYNC2H1 ACAN UNC5B	3.41e-04	191	32	3	cc9a6a8fad17d6e1a08a68ab7512ae06b1249051
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	DYNC2H1 ACAN UNC5B	3.41e-04	191	32	3	c16b920ee69ea8536e020ac3475abf1ce972c1e6
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic-lymphocyte-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TCF19 RFX8 FABP5	3.41e-04	191	32	3	56b45259dfc38bd5ea43b0e3adf47e7e2c043a5d
ToppCell	IPF-Epithelial-Ciliated\|IPF / Disease state, Lineage and Cell class	DNAH12 SHANK2 DYNC2H1	3.46e-04	192	32	3	354adc1354bf596fbc60dd45c0169688e6f45165
ToppCell	facs-MAT-Fat-24m-Endothelial-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC5B NOTCH1 FABP5	3.52e-04	193	32	3	ba9a47e2dc01efa6d2a99b1631d4951fac2648d4
ToppCell	facs-MAT-Fat-24m-Endothelial-endothelial_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC5B NOTCH1 FABP5	3.52e-04	193	32	3	724bb613fa434add5b1c5586b629328f819fbdfe
ToppCell	facs-MAT-Fat-24m-Endothelial\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC5B NOTCH1 FABP5	3.52e-04	193	32	3	737e540c72a3cfe8dbd4c0f139f7d729a166793a
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDM5B SEPTIN10 FABP5	3.52e-04	193	32	3	bc7e0b6b07be91901f02f1524fb81f3c538ab6b9
ToppCell	Control-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	DNAH12 SHANK2 DYNC2H1	3.57e-04	194	32	3	958e648138676d46698090b4046cb484083ae449
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	DNAH12 SHANK2 DYNC2H1	3.62e-04	195	32	3	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	DNAH12 SHANK2 DYNC2H1	3.62e-04	195	32	3	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	IPF-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	DNAH12 SHANK2 DYNC2H1	3.62e-04	195	32	3	21dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	UNC5B NOTCH1 FABP5	3.68e-04	196	32	3	ae46d4b00be92e64e46252dcc156161b171eded4
ToppCell	IPF-Epithelial\|IPF / Disease state, Lineage and Cell class	DNAH12 SHANK2 DYNC2H1	3.68e-04	196	32	3	87d9881cfec461a5d89b688a83749b618c519485
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SEPTIN11 DYNC2H1 UNC5B	3.73e-04	197	32	3	c165c6fd12dc649b39e920d8528e2eb65c61956b
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 SHANK2 DYNC2H1	3.73e-04	197	32	3	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	356C-Myeloid-Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SEPTIN11 PARP12 FABP5	3.73e-04	197	32	3	896242e1651435bbc5b6521417e1aca36c215acd
ToppCell	Non-neuronal-Dividing-Radial_Glia-vRG-20\|World / Primary Cells by Cluster	SEPTIN11 NOTCH1 FABP5	3.79e-04	198	32	3	bce0bc1e3f2257e0f42a1fa6e5b57cf71e4514ba
ToppCell	(5)_Epithelial_cells-(5)_Epi_stratified\|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	UNC5B NOTCH1 FABP5	3.79e-04	198	32	3	b3aec042912ce53bd86e86b6761a0604d9998ab5
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	DYNC2H1 ACAN UNC5B	3.79e-04	198	32	3	bc9c9f2c87282b5ef8514773e065d2a6b5dde338
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	UNC5B NOTCH1 FABP5	3.79e-04	198	32	3	19d8ff3a4f911b13ecc34844202925475ad4d2ab
ToppCell	(1)_T_cell_dividing\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	TCF19 NOTCH1 FABP5	3.79e-04	198	32	3	dac3a16e3a070a37f4d0ea37633c23fdc8a9c70a
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEPTIN11 ACAN FABP5	3.85e-04	199	32	3	9e32644b93fb1c4946dbe388fd5c357304d14e36
ToppCell	CV-Moderate-2\|CV / Virus stimulation, Condition and Cluster	TCF19 WDR43 FABP5	3.85e-04	199	32	3	2d98424a5247e87f98095c11fb945289092a9d75
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 SHANK2 DYNC2H1	3.85e-04	199	32	3	92fdf6e2f0786ab2ab78126e9131a93794168139
ToppCell	Transverse-T_cell-Tfh\|T_cell / Region, Cell class and subclass	NSD1 NOTCH1 NOD2	3.85e-04	199	32	3	33ffea12b8228e0b5bd8942531c3b21d24224725
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SEPTIN11 TCF19 FABP5	3.85e-04	199	32	3	e1190b1c2d21fed313bb58e24d0e6365de6e6599
ToppCell	severe-Lymphocytic-Prol._cells\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SEPTIN11 TCF19 FABP5	3.85e-04	199	32	3	b24315952b6ac6c8d2d3a7bd949a5b5392624d4e
ToppCell	ILEUM-inflamed-(1)_Highly_activated_T_cells\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TCF19 NOTCH1 FABP5	3.90e-04	200	32	3	6ff811fdfe49b5b0aea0e88fae80bfaaf40eb7c4
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	DNAH12 NOTCH1 WDR43	3.90e-04	200	32	3	ef222dc4a205d670172dae74990bdb952ac92e5b
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Macroglial-Astrocyte\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	DNAH12 NOTCH1 WDR43	3.90e-04	200	32	3	98a994692440cb4f505b050276f0c8022c814a21
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZFC3H1 TRIM22 ITSN2	3.90e-04	200	32	3	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	ILEUM-inflamed-(1)_T_cell-(1)_Highly_activated_T_cells\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TCF19 NOTCH1 FABP5	3.90e-04	200	32	3	d92d3bc63a56a604d7b1d49e62d4304e5e4017f2
Computational	Neighborhood of PTPRC	KDM5A TRIM22 PARP12	2.56e-04	68	20	3	GNF2_PTPRC
Disease	syndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)	KDM5B KDM5A	6.83e-06	4	32	2	DOID:0060809 (implicated_via_orthology)
Disease	Autistic Disorder	SHANK1 NSD1 DAO KDM5B SHANK2	8.63e-06	261	32	5	C0004352
Disease	autism spectrum disorder (implicated_via_orthology)	SHANK1 KDM5B SHANK2 KDM5A	2.18e-05	152	32	4	DOID:0060041 (implicated_via_orthology)
Disease	intellectual disability (implicated_via_orthology)	KDM5B KDM5A ITSN2	7.42e-05	75	32	3	DOID:1059 (implicated_via_orthology)
Disease	syndromic intellectual disability (implicated_via_orthology)	KDM5B KDM5A	1.35e-04	16	32	2	DOID:0050888 (implicated_via_orthology)
Disease	Bipolar Disorder	SEPTIN11 DAO SHANK2 POLG NOD2	1.52e-04	477	32	5	C0005586
Disease	Adenoid Cystic Carcinoma	NSD1 CMTR2 NOTCH1	1.74e-04	100	32	3	C0010606
Disease	haptoglobin measurement	TLE7 CMTR2	2.36e-04	21	32	2	EFO_0004640
Disease	Mental Retardation, Psychosocial	NSD1 SHANK2 KDM5A	4.59e-04	139	32	3	C0025363
Disease	Profound Mental Retardation	NSD1 SHANK2 KDM5A	4.59e-04	139	32	3	C0020796
Disease	Mental deficiency	NSD1 SHANK2 KDM5A	4.59e-04	139	32	3	C0917816
Disease	Colonic Neoplasms	KDM5B TCF19 NOTCH1	5.96e-04	152	32	3	C0009375
Disease	prostate cancer (is_marker_for)	KDM5B KDM5A FABP5	6.42e-04	156	32	3	DOID:10283 (is_marker_for)
Disease	Malignant tumor of colon	KDM5B TCF19 NOTCH1	6.79e-04	159	32	3	C0007102
Disease	alcohol use disorder (implicated_via_orthology)	KDM5B KDM5A NOTCH1	1.22e-03	195	32	3	DOID:1574 (implicated_via_orthology)
Disease	sitting height ratio	NSD1 ITSN2	1.41e-03	51	32	2	EFO_0007118
Disease	Influenza	TRIM22 PARP12	1.46e-03	52	32	2	C0021400
Disease	Squamous cell carcinoma of the head and neck	MAPK9 NOTCH1	1.46e-03	52	32	2	C1168401
Disease	renal agenesis, unilateral	KDM5A ACAN	2.00e-03	61	32	2	MONDO_0019636

Protein segments in the cluster

Peptide	Gene	Start	Entry
NAHCVDCETQNPKWA	AGAP9	521	Q5VTM2
VNAELCTQAWCKFHE	CMTR2	106	Q8IYT2
NHEHVNVSWCFVCSE	NSD1	1701	Q96L73
EWIQAHVQCEGLAEQ	ITSN2	1406	Q9NZM3
NNIQDHNTIWEGCCR	DAO	251	P14920
GCVIFQGTDHIDQWN	MAPK9	221	P45984
WQGQTCEVDINECVL	NOTCH1	861	P46531
EEGTWVCLQNCHLAV	DNAH12	2546	Q6ZR08
CAQDVWATHEVFQQQ	POLG	396	P54098
DGSCNQWFHQVCVGV	KDM5B	1506	Q9UGL1
VCNFTDGALVQHQEW	FABP5	86	Q01469
VQCDGGCDEWFHQVC	KDM5A	1626	P29375
EHCNIDQEVCEEGWN	ACAN	2311	P16112
VDAICQQNFDWRVCG	PARP12	571	Q9H0J9
AGISICEQWVIVCNH	DYNC2H1	286	Q8NCM8
CEQWVIVCNHLTGQV	DYNC2H1	291	Q8NCM8
EIAQCEVFHQCEQWG	CARS2	286	Q9HA77
PWGVVQVENENHCDF	SEPTIN11	256	Q9NVA2
GELCVCAAIQWLQDN	RWDD2A	116	Q9UIY3
VCCKDENGWHEIHQA	SHANK2	291	Q9UPX8
DENGWQEIHQACQRG	SHANK1	311	Q9Y566
QEETVAWVQCDGCDV	TCF19	301	Q9Y242
EHCCWPDVGQEDIFQ	NOD2	351	Q9HC29
GVIQWLVDNFCICEE	RFX8	21	Q6ZV50
ACFHGFVEIWDLQNQ	TLE7	266	A0A1W2PR48
CGHEWNTENCVEFQK	SLC6A11	171	P48066
CNGEWVSQNDHVTQE	UNC5B	81	Q8IZJ1
PWGVVQVENENHCDF	SEPTIN10	281	Q9P0V9
IFCQTGGVEDQEEWH	ZBED1	551	O96006
CWVCELSQEHQGHQT	TRIM22	116	Q8IYM9
TGTCNDDDCQWQHIQ	ZFC3H1	1191	O60293
DQLATCWQAEHCGEV	USP6	486	P35125
DNRVNCIQWHQDSGC	WDR43	126	Q15061