Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentlateral plasma membrane

ERBB3 ANK3 DVL2 APC PKD1 TBCD

6.48e-05901596GO:0016328
GeneOntologyCellularComponentpostsynaptic density

TANC2 ANK2 ANK3 SH2D5 ADCY8 ITPR1 GRID2IP MTMR2 SLITRK5 AFDN INSYN2B NOTCH1

1.80e-0445115912GO:0014069
GeneOntologyCellularComponentapical junction complex

SHROOM3 AOC1 ANK3 APC PARD6G AFDN TBCD

2.11e-041581597GO:0043296
GeneOntologyCellularComponentpostsynapse

TANC2 CACNA1A FILIP1 ERBB3 ANK2 ANK3 SYNE1 APC ARHGAP39 SH2D5 ADCY8 ITPR1 GRID2IP KCNJ6 MTMR2 SLITRK5 AFDN INSYN2B NOTCH1

2.76e-04101815919GO:0098794
GeneOntologyCellularComponentasymmetric synapse

TANC2 ANK2 ANK3 SH2D5 ADCY8 ITPR1 GRID2IP MTMR2 SLITRK5 AFDN INSYN2B NOTCH1

2.99e-0447715912GO:0032279
GeneOntologyCellularComponentprotein kinase CK2 complex

CSNK2A1 CSNK2A3

3.42e-0441592GO:0005956
GeneOntologyCellularComponentpostsynaptic specialization

TANC2 ANK2 ANK3 SH2D5 ADCY8 ITPR1 GRID2IP MTMR2 SLITRK5 AFDN INSYN2B NOTCH1

4.82e-0450315912GO:0099572
GeneOntologyCellularComponentsynaptic membrane

CACNA1A ERBB3 ANK2 ANK3 SYNE1 ADCY8 ITPR1 GRID2IP KCNJ6 MTMR2 SLITRK5 AFDN NOTCH1

5.31e-0458315913GO:0097060
GeneOntologyCellularComponentneuron to neuron synapse

TANC2 ANK2 ANK3 SH2D5 ADCY8 ITPR1 GRID2IP MTMR2 SLITRK5 AFDN INSYN2B NOTCH1

6.79e-0452315912GO:0098984
GeneOntologyCellularComponenttight junction

AOC1 ANK3 APC PARD6G AFDN TBCD

6.88e-041391596GO:0070160
GeneOntologyCellularComponentMOZ/MORF histone acetyltransferase complex

BRPF1 BRD1

1.18e-0371592GO:0070776
GeneOntologyCellularComponentnuclear membrane

RBM15 SYNE1 APC ITPR1 LPIN1 TNRC18 TMEM168 MCM3AP PHLPP1

1.44e-033491599GO:0031965
GeneOntologyCellularComponentH3 histone acetyltransferase complex

BRPF1 BRD1

1.56e-0381592GO:0070775
DomainEPHD

KMT2D BRPF1 BRD1 RAI1

3.12e-05221574PS51805
DomainSNO

SBNO2 SBNO1

7.02e-0521572IPR026741
DomainSBNO_Helicase_C_dom

SBNO2 SBNO1

7.02e-0521572IPR026937
DomainHelicase_C_4

SBNO2 SBNO1

7.02e-0521572PF13871
DomainRunt

RUNX2 RUNX1

2.09e-0431572PF00853
DomainRUNT

RUNX2 RUNX1

2.09e-0431572PS51062
DomainTF_Runt-rel_RUNX

RUNX2 RUNX1

2.09e-0431572IPR016554
DomainRunxI

RUNX2 RUNX1

2.09e-0431572PF08504
DomainRunt_dom

RUNX2 RUNX1

2.09e-0431572IPR013524
DomainRunxI_C_dom

RUNX2 RUNX1

2.09e-0431572IPR013711
DomainRunx_central_dom

RUNX2 RUNX1

2.09e-0431572IPR027384
Domain-

RUNX2 RUNX1

2.09e-04315724.10.770.10
DomainAML1_Runt

RUNX2 RUNX1

2.09e-0431572IPR000040
DomainCadherin_tail

PCDHA13 PCDHA12 PCDHA3 PCDHA2

2.56e-04371574PF15974
DomainCadherin_CBD

PCDHA13 PCDHA12 PCDHA3 PCDHA2

2.56e-04371574IPR031904
DomainPWWP

BRPF1 BRD1 DNMT3A

5.98e-04201573SM00293
DomainAnk

TANC2 ANK2 ANK3 ANKRD54 ANKRD13C NFKBIA ANKRD11 NOTCH1

7.02e-042281578PF00023
DomainTPR

TANC2 TTC24 PRPF6 TTC34 TTC7B KLC3

7.79e-041291576SM00028
DomainPWWP

BRPF1 BRD1 DNMT3A

9.12e-04231573PF00855
DomainPWWP_dom

BRPF1 BRD1 DNMT3A

9.12e-04231573IPR000313
DomainTPR_repeat

TANC2 TTC24 PRPF6 TTC34 TTC7B KLC3

9.14e-041331576IPR019734
DomainPHD

RSF1 KMT2D BRPF1 BRD1 RAI1

9.26e-04891575SM00249
DomainZnf_PHD

RSF1 KMT2D BRPF1 BRD1 RAI1

1.02e-03911575IPR001965
Domainp53/RUNT-type_TF_DNA-bd

RUNX2 RUNX1

1.03e-0361572IPR012346
Domain-

RUNX2 RUNX1

1.03e-03615722.60.40.720
DomainFF_domain

TCERG1L ARHGAP5

1.03e-0361572IPR002713
DomainFF

TCERG1L ARHGAP5

1.03e-0361572PS51676
DomainFF

TCERG1L ARHGAP5

1.03e-0361572PF01846
DomainFF

TCERG1L ARHGAP5

1.03e-0361572SM00441
DomainPWWP

BRPF1 BRD1 DNMT3A

1.04e-03241573PS50812
Domain-

TANC2 ANK2 ANK3 ANKRD54 ANKRD13C NFKBIA ANKRD11 NOTCH1

1.21e-0324815781.25.40.20
DomainZF_PHD_2

RSF1 KMT2D BRPF1 BRD1 RAI1

1.24e-03951575PS50016
DomainZF_PHD_1

RSF1 KMT2D BRPF1 BRD1 RAI1

1.30e-03961575PS01359
DomainANK

TANC2 ANK2 ANK3 ANKRD54 ANKRD13C NFKBIA ANKRD11 NOTCH1

1.30e-032511578SM00248
DomainANK_REPEAT

TANC2 ANK2 ANK3 ANKRD54 ANKRD13C NFKBIA ANKRD11 NOTCH1

1.37e-032531578PS50088
DomainAnkyrin_rpt-contain_dom

TANC2 ANK2 ANK3 ANKRD54 ANKRD13C NFKBIA ANKRD11 NOTCH1

1.41e-032541578IPR020683
DomainANK_REP_REGION

TANC2 ANK2 ANK3 ANKRD54 ANKRD13C NFKBIA ANKRD11 NOTCH1

1.41e-032541578PS50297
DomainPKD

PKD1 GPNMB

1.43e-0371572PF00801
DomainHr1

RTKN2 PKN1

1.43e-0371572SM00742
DomainTPR-contain_dom

TANC2 TTC24 PRPF6 TTC34 TTC7B KLC3

1.70e-031501576IPR013026
DomainAnkyrin_rpt

TANC2 ANK2 ANK3 ANKRD54 ANKRD13C NFKBIA ANKRD11 NOTCH1

1.71e-032621578IPR002110
Domain-

TANC2 TTC24 PRPF6 TTC34 TTC7B KLC3 CFAP46

1.86e-0320715771.25.40.10
DomainEPL1

BRPF1 BRD1

1.90e-0381572PF10513
DomainEnhancer_polycomb-like_N

BRPF1 BRD1

1.90e-0381572IPR019542
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ERBB3 ANK2 ANK3 STAG1 PEG10 SYNE1 APC TRIOBP WHAMM NCAPH2 RUNX1 SEC31B ANKRD54 DMAP1 ARHGAP5 TTC7B DNAJC14 TMEM168 SBNO1 KCNJ6 PKD1 MTMR2 AFDN GPRASP2

7.41e-0912851622435914814
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

SAMD1 RBM15 SAV1 PCDHA13 CHD8 NCAPH2 DMAP1 RTKN2 LLGL2 SF3B3 NF1 DNAJC14 SBNO1 CSNK2A1 MCM3AP STEEP1 CEP135 SEC16A ANKRD11 PHLPP1 BRD1 MAP2K7 NXF1 RAD54L

1.37e-0813271622432694731
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RBM15 RSF1 CHD8 PRPF6 CUL7 USP5 LONP1 NF1 CSNK2A1 MCM3AP SEC16A DDX23 CCAR2 AFDN NXF1 RAI1

7.90e-086531621622586326
Pubmed

Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.

PCDHA13 PCDHA12 PCDHA3 PCDHA2 DNMT3A

8.15e-0824162524698270
Pubmed

The molecular profile of adult T-cell acute lymphoblastic leukemia: mutations in RUNX1 and DNMT3A are associated with poor prognosis in T-ALL.

RUNX1 NOTCH1 DNMT3A

9.92e-083162323341344
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

RBM15 ANK3 TRIOBP ARHGAP39 CUL7 ITPR1 ARHGAP5 LONP1 KMT2D TTC7B CCNB2 CSNK2A1 CEP135 SEC16A MTMR2 PHLPP1 UBR3 PDP2 CCAR2 NOTCH1

1.07e-0710491622027880917
Pubmed

The functional interactome landscape of the human histone deacetylase family.

IKZF2 STAG1 RBM12B PRPF6 RUNX1 TNRC18 BBX CSNK2A1 SEC16A ANKRD11 CCAR2

1.27e-072891621123752268
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

EPHB4 TANC2 SEMA6C SHROOM3 INPP5E CHD8 SBNO2 TNRC18 KMT2D LLGL2 DNAJC14 MCM3AP PKD1 SEC16A ANKRD11 PDIA5 PKN1 NOTCH1 RAI1 TBCD

2.44e-0711051622035748872
Pubmed

Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons.

PCDHA13 PCDHA12 PCDHA3 PCDHA2

5.95e-0715162415640798
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TANC2 CACNA1A SHROOM3 ANK2 ANK3 SYNE1 DVL2 APC TRIOBP CHD8 ARHGAP39 NF1 CSNK2A1 SEC16A CCAR2 AFDN PKN1 RAI1

6.43e-079631621828671696
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

RBM15 ANK3 PRPF6 MON1A LOXHD1 GRID2IP CSNK2A1 ANKRD11 FGB DDX23 CSNK2A3 MINDY1 RAI1

6.66e-074971621336774506
Pubmed

Functional proteomics mapping of a human signaling pathway.

ANK3 STAG1 PEG10 ARHGAP5 USP5 KMT2D ZNHIT6 MCM3AP PKD1 CEP135 AFDN GPNMB BRD1 TBCD

7.94e-075911621415231748
Pubmed

Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.

PCDHA13 PCDHA12 PCDHA3 PCDHA2

1.03e-0617162429911975
Pubmed

CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity.

PCDHA13 PCDHA12 PCDHA3 PCDHA2

1.32e-0618162415570159
Pubmed

Genomic organization of the family of CNR cadherin genes in mice and humans.

PCDHA13 PCDHA12 PCDHA3 PCDHA2

1.32e-0618162410662547
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

TANC2 RBM15 SHROOM3 APC SAV1 CUL7 LONP1 NF1 PIK3C2A SEC16A AFDN NOTCH1

1.36e-064461621224255178
Pubmed

Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis.

ACOX1 CPT1B PPARGC1A

1.96e-066162311018072
Pubmed

Notch1 regulates progenitor cell proliferation and differentiation during mouse yolk sac hematopoiesis.

EPHB4 RUNX1 NOTCH1

1.96e-066162324583642
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

DOCK4 SAMD1 RSF1 APC SAV1 LACTB LPIN1 LONP1 TNRC18 ZNHIT6 FGB MAN1B1 TBCD DNMT3A

4.70e-066891621436543142
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TANC2 SAMD1 RSF1 DVL2 CHD8 CUL7 ANKRD54 DMAP1 ZNHIT6 SF3B3 CSNK2A1 BRPF1 MCM3AP SEC16A FGB BRD1 MAP2K7 RAI1

5.07e-0611161621831753913
Pubmed

DNA cloning using in vitro site-specific recombination.

FILIP1 AICDA ACOX1 APC TRIOBP ZCCHC2 ADCY8 DMAP1 ANKRD13C CCNB2 MYPN CCAR2 RNF39 PNMA6A GPRASP2

5.11e-067941621511076863
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

SAMD1 STAG1 RSF1 CHD8 DMAP1 BBX SBNO1 CSNK2A1 BRPF1 STEEP1 BRD1 RAI1 DNMT3A

6.05e-066081621336089195
Pubmed

ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.

RSF1 CHD8 DMAP1 SF3B3 CSNK2A1 CSNK2A3 DNMT3A

7.03e-06150162728242625
Pubmed

Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.

PCDHA13 PCDHA12 PCDHA3 PCDHA2 PCDHB18P

7.10e-0657162532633719
Pubmed

CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.

PCDHA13 PCDHA12 PCDHA3 PCDHA2 PCDHB18P

7.74e-0658162530377227
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

STAG1 SYNE1 APC TRIOBP PRPF6 ITPR1 RTKN2 ZNHIT6 LLGL2 SF3B3 CCNB2 MYPN CEP135 FGB DDX23 CCAR2 NXF1 TBCD

8.10e-0611551621820360068
Pubmed

Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.

PCDHA13 PCDHA12 PCDHA3 PCDHA2

8.51e-0628162415347688
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TANC2 DOCK4 RBM15 SHROOM3 INPP5E APC NF1 PIK3C2A DSTYK SEC16A ANKRD11 AFDN BRD1 MAP2K7 KLC3

1.33e-058611621536931259
Pubmed

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.

PCDHA13 PCDHA12 PCDHA3 PCDHA2 PCDHB18P

1.70e-0568162511230163
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

FILIP1 RBM15 ERCC5 ARHGAP39 RUNX1 KMT2D NF1 CSNK2A1 TLE4 BRPF1 SEC16A CCAR2 AFDN PKN1

1.73e-057741621415302935
Pubmed

Efficient isolation of novel mouse genes differentially expressed in early postimplantation embryos.

CHD8 IGF2 NF1 TLE4

1.89e-053416247490078
Pubmed

Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes.

DVL2 APC CHD8 CCAR2

1.89e-0534162430894540
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

TANC2 RBM15 SHROOM3 STAG1 MAGEE2 CHD8 PRPF6 SEC31B SF3B3 NF1 DDX23 MAP2K7

1.99e-055821621220467437
Pubmed

Identification of epilepsy genes in human and mouse.

CACNA1A ITPR1 KCNJ6

2.12e-0512162311700294
Pubmed

The cDNA cloning of the transcripts of human PEBP2alphaA/CBFA1 mapped to 6p12.3-p21.1, the locus for cleidocranial dysplasia.

RUNX2 RUNX1

2.16e-05216229233771
Pubmed

TIGIT and Helios Are Highly Expressed on CD4+ T Cells in Sézary Syndrome Patients.

IKZF2 TIGIT

2.16e-052162227592800
Pubmed

The receptor tyrosine kinase EPHB4 has tumor suppressor activities in intestinal tumorigenesis.

EPHB4 APC

2.16e-052162219738063
Pubmed

Casein kinase II phosphorylates I kappa B alpha at S-283, S-289, S-293, and T-291 and is required for its degradation.

CSNK2A1 NFKBIA

2.16e-05216228622692
Pubmed

Inositol 1,4,5-trisphosphate receptor localization and stability in neonatal cardiomyocytes requires interaction with ankyrin-B.

ANK2 ITPR1

2.16e-052162214722080
Pubmed

PGC-1α Protects from Notch-Induced Kidney Fibrosis Development.

PPARGC1A NOTCH1

2.16e-052162228751525
Pubmed

Fasting induces the expression of PGC-1α and ERR isoforms in the outer stripe of the outer medulla (OSOM) of the mouse kidney.

PPARGC1A SLC9A3

2.16e-052162222073226
Pubmed

Inhibition of CK2α down-regulates Notch1 signalling in lung cancer cells.

CSNK2A1 NOTCH1

2.16e-052162223651443
Pubmed

CK2α phosphorylates DBC1 and is involved in the progression of gastric carcinoma and predicts poor survival of gastric carcinoma patients.

CSNK2A1 CCAR2

2.16e-052162224962073
Pubmed

Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer.

DVL2 APC

2.16e-052162220663899
Pubmed

Peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC1alpha) is a metabolic regulator of intestinal epithelial cell fate.

APC PPARGC1A

2.16e-052162221467224
Pubmed

Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice.

APC IGF2

2.16e-052162215731405
Pubmed

Runx1/AML1/Cbfa2 mediates onset of mesenchymal cell differentiation toward chondrogenesis.

RUNX2 RUNX1

2.16e-052162216059634
Pubmed

Study of Strawberry Notch homolog 1 and 2 expression in human glioblastoma.

SBNO2 SBNO1

2.16e-052162236695974
Pubmed

Assignment of casein kinase 2 alpha sequences to two different human chromosomes.

CSNK2A1 CSNK2A3

2.16e-05216221577469
Pubmed

Decreased NHE3 expression in colon cancer is associated with DNA damage, increased inflammation and tumor growth.

APC SLC9A3

2.16e-052162236042372
Pubmed

Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia.

RUNX2 RUNX1

2.16e-052162223321257
Pubmed

Identification of novel Runx2 targets in osteoblasts: cell type-specific BMP-dependent regulation of Tram2.

RUNX2 TRAM2

2.16e-052162217486635
Pubmed

Electrophysiology and GABA-immunocytochemistry in the vestibular nuclei of normal (C57BL/6J) and Leaner mutant mice.

CACNA1A KCNJ6

2.16e-05216228719615
Pubmed

AKT signaling promotes DNA damage accumulation and proliferation in polycystic kidney disease.

INPP5E PKD1

2.16e-052162231625572
Pubmed

Inhibition of Notch1 signaling by Runx2 during osteoblast differentiation.

RUNX2 NOTCH1

2.16e-052162220740684
Pubmed

Abnormal mechanical stress on bicuspid aortic valve induces valvular calcification and inhibits Notch1/NICD/Runx2 signal.

RUNX2 NOTCH1

2.16e-052162236908813
Pubmed

Expression of AML/Runx and ETO/MTG family members during hematopoietic differentiation of embryonic stem cells.

RUNX2 RUNX1

2.16e-052162217533052
Pubmed

A microRNA/Runx1/Runx2 network regulates prostate tumor progression from onset to adenocarcinoma in TRAMP mice.

RUNX2 RUNX1

2.16e-052162227634876
Pubmed

Identification and expression of a novel 3'-exon of mouse Runx1/Pebp2alphaB/Cbfa2/AML1 gene.

RUNX2 RUNX1

2.16e-052162210903914
Pubmed

Investigating a downstream gene of Gpnmb using the systems genetics method.

STC1 GPNMB

2.16e-052162231057322
Pubmed

Notch1 counteracts WNT/β-catenin signaling through chromatin modification in colorectal cancer.

APC NOTCH1

2.16e-052162222863622
Pubmed

Polycystin-1 regulates skeletogenesis through stimulation of the osteoblast-specific transcription factor RUNX2-II.

RUNX2 PKD1

2.16e-052162218321855
Pubmed

AML1/Runx1 rescues Notch1-null mutation-induced deficiency of para-aortic splanchnopleural hematopoiesis.

RUNX1 NOTCH1

2.16e-052162216888092
Pubmed

Three-dimensional atomic structure of a catalytic subunit mutant of human protein kinase CK2.

CSNK2A1 CSNK2A3

2.16e-052162214646071
Pubmed

Cholinergic augmentation of insulin release requires ankyrin-B.

ANK2 ITPR1

2.16e-052162220234002
Pubmed

Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit.

CSNK2A1 CSNK2A3

2.16e-052162212860116
Pubmed

Stanniocalcin-1 augments stem-like traits of glioblastoma cells through binding and activating NOTCH1.

STC1 NOTCH1

2.16e-052162229196129
Pubmed

RUNX1 and RUNX2 transcription factors function in opposing roles to regulate breast cancer stem cells.

RUNX2 RUNX1

2.16e-052162232180230
Pubmed

Intermittent glucocorticoid treatment improves muscle metabolism via the PGC1α/Lipin1 axis in an aging-related sarcopenia model.

LPIN1 PPARGC1A

2.16e-052162238702076
Pubmed

Soluble IGF2 receptor rescues Apc(Min/+) intestinal adenoma progression induced by Igf2 loss of imprinting.

APC IGF2

2.16e-052162216488992
Pubmed

The H19 locus acts in vivo as a tumor suppressor.

APC IGF2

2.16e-052162218719115
Pubmed

Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles.

RUNX2 RUNX1

2.16e-052162217290219
Pubmed

Casein kinase 2 binds to the C terminus of Na+/H+ exchanger 3 (NHE3) and stimulates NHE3 basal activity by phosphorylating a separate site in NHE3.

SLC9A3 CSNK2A1

2.16e-052162218614797
Pubmed

Molecular insights into the recognition of N-terminal histone modifications by the BRPF1 bromodomain.

BRPF1 BRD1

2.16e-052162224333487
Pubmed

Runx1 and Runx2 inhibit fibrotic conversion of cellular niches for hematopoietic stem cells.

RUNX2 RUNX1

2.16e-052162235551452
Pubmed

Cilia-like structures and polycystin-1 in osteoblasts/osteocytes and associated abnormalities in skeletogenesis and Runx2 expression.

RUNX2 PKD1

2.16e-052162216905538
Pubmed

Cholangiocarcinomas associated with long-term inflammation express the activation-induced cytidine deaminase and germinal center-associated nuclear protein involved in immunoglobulin V-region diversification.

AICDA MCM3AP

2.16e-052162219578742
Pubmed

The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytes.

ANK2 ANK3

2.16e-052162211781319
Pubmed

Structural basis of diverse membrane target recognitions by ankyrins.

ANK2 ANK3

2.16e-052162225383926
Pubmed

Ankyrin B modulates the function of Na,K-ATPase/inositol 1,4,5-trisphosphate receptor signaling microdomain.

ANK2 ITPR1

2.16e-052162218303017
Pubmed

Insulin-like growth factor II supply modifies growth of intestinal adenoma in Apc(Min/+) mice.

APC IGF2

2.16e-052162210706126
Pubmed

Co-Expression of TIGIT and Helios Marks Immunosenescent CD8+ T Cells During Aging.

IKZF2 TIGIT

2.16e-052162235651622
Pubmed

Molecular cloning of the human casein kinase II alpha subunit.

CSNK2A1 CSNK2A3

2.16e-05216222752008
Pubmed

Structure and sequence of an intronless gene for human casein kinase II-alpha subunit.

CSNK2A1 CSNK2A3

2.16e-05216228420794
Pubmed

A striking organization of a large family of human neural cadherin-like cell adhesion genes.

PCDHA13 PCDHA12 PCDHA3 PCDHA2 PCDHB18P

2.24e-0572162510380929
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

SHROOM3 RBM12B MCM3AP SEC16A SLITRK5 NOTCH1 RAI1

2.30e-05180162735198878
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

RBM15 RSF1 CHD8 PRPF6 KMT2D CSNK2A1 DDX23 DNMT3A

2.50e-05251162831076518
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDHA13 PCDHA12 PCDHA3 PCDHA2 PCDHB18P

2.56e-0574162510817752
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

RBM15 RSF1 APC CHD8 DMAP1 USP5 MYPN SEC16A AFDN PKN1 CTU1

2.61e-055031621116964243
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

KMT2D SF3B3 PIK3C2A MCM3AP SEC16A CCAR2 NOTCH1

2.64e-05184162732908313
Pubmed

The DNA sequence and comparative analysis of human chromosome 5.

PCDHA13 PCDHA12 PCDHA3 PCDHA2 INSYN2B

2.73e-0575162515372022
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

PCDHA13 PCDHA12 PCDHA3 PCDHA2 PCDHB18P

3.11e-0577162510835267
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

SAMD1 STAG1 PEG10 CHD8 PRPF6 KMT2D SBNO1 MCM3AP DDX23

3.42e-05341162932971831
Pubmed

Comparative analyses of the Dominant megacolon-SOX10 genomic interval in mouse and human.

TRIOBP ANKRD54 C22orf23

3.48e-0514162310384052
Pubmed

Diabetic modifier QTLs identified in F2 intercrosses between Akita and A/J mice.

ACOX1 ADCY8 ITPR1

3.48e-0514162316964447
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDHA13 PCDHA12 PCDHA3 PCDHA2 PCDHB18P

3.74e-0580162510716726
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

TANC2 CACNA1A ANK2 APC ARHGAP39 SH2D5 NF1 PIK3C2A ABLIM2

3.92e-05347162917114649
Pubmed

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.

DOCK4 ANK2 ANK3 FRS3 ARHGAP39 SLITRK5 AFDN

4.09e-05197162736604605
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

TANC2 CACNA1A ANK2 ANK3 SYNE1 APC ARHGAP39 LACTB ARHGAP5 USP5 LONP1 SF3B3 NF1 TTC7B CSNK2A1 SEC16A MTMR2 AFDN ABLIM2

4.11e-0514311621937142655
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SEMA6C SHROOM3 INPP5E TRIOBP CHD8 PCDHA3 GRAMD4 DMAP1 SF3B3 MINDY1 RAI1

4.12e-055291621114621295
InteractionPCDHA10 interactions

SAMD1 PCDHA13 PCDHA12 PCDHA3 PCDHA2

7.00e-07221605int:PCDHA10
InteractionPCDHA8 interactions

EPHB4 SGCB PCDHA13 PCDHA12 PCDHA3 PCDHA2

4.79e-06551606int:PCDHA8
InteractionHDAC1 interactions

IKZF2 STAG1 DVL2 APC CHD8 RUNX2 RUNX1 DMAP1 TNRC18 KMT2D BBX CIITA CSNK2A1 TLE4 NFKBIA CEP135 PHLPP1 CCAR2 CSNK2A3 GPRASP2 NXF1 NOTCH1 RAI1 DNMT3A

7.19e-06110816024int:HDAC1
InteractionHDAC4 interactions

TANC2 CACNA1A IKZF2 STAG1 INPP5E APC CHD8 CUL7 RUNX2 ITPR1 ARHGAP5 LONP1 AHRR NF1 TTC7B CIITA NFKBIA ANKRD11 CMTM5

7.38e-0674416019int:HDAC4
InteractionSENP3 interactions

SAMD1 RBM15 SAV1 PRPF6 KMT2D BBX CSNK2A1 MCM3AP DDX23 AFDN NXF1

2.97e-0530116011int:SENP3
InteractionCGNL1 interactions

DVL2 APC CEP135 PDIA5 AFDN

3.12e-05461605int:CGNL1
InteractionPPARD interactions

SAMD1 DVL2 APC CUL7 PPARGC1A MCM3AP TBCD

4.16e-051171607int:PPARD
InteractionTSPOAP1 interactions

CACNA1A BEND5 ANKRD11 GPRASP2

4.25e-05251604int:TSPOAP1
InteractionCTNNB1 interactions

TANC2 USP49 SHROOM3 ANK2 ANK3 DVL2 APC CHD8 PRPF6 RUNX2 RUNX1 LACTB ARHGAP5 KMT2D CSNK2A1 PKD1 SEC16A AFDN PKN1 NXF1 NOTCH1

5.08e-05100916021int:CTNNB1
InteractionNOLC1 interactions

APC CUL7 ZNHIT6 LLGL2 LOXHD1 NF1 CSNK2A1 DDX23 CSNK2A3 NXF1 KLC3

5.95e-0532516011int:NOLC1
InteractionLYST interactions

LLGL2 DNAJC14 CSNK2A1 CSNK2A3 KLC3

6.25e-05531605int:LYST
InteractionMARK2 interactions

TMEM74 RSF1 DVL2 APC PARD6G NF1 PKD1 PHLPP1 AFDN FUCA1

6.96e-0527416010int:MARK2
Cytoband5q31

PCDHA13 PCDHA12 PCDHA3 PCDHA2 PCDHB18P

5.77e-0511516255q31
CytobandEnsembl 112 genes in cytogenetic band chr22q13

TRIOBP NCAPH2 CPT1B GRAMD4 ANKRD54 C22orf23 BRD1

1.83e-043301627chr22q13
Cytoband22q13.33

NCAPH2 CPT1B BRD1

3.32e-0438162322q13.33
Cytoband5p15.3

AHRR SLC9A3

5.47e-041016225p15.3
GeneFamilyClustered protocadherins

PCDHA13 PCDHA12 PCDHA3 PCDHA2 PCDHB18P

3.99e-0564108520
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TANC2 TTC24 TTC34 TTC7B KLC3 CFAP46

6.56e-051151086769
GeneFamilyAnkyrin repeat domain containing

TANC2 ANK2 ANK3 ANKRD54 ANKRD13C NFKBIA ANKRD11 NOTCH1

1.02e-042421088403
GeneFamilyPWWP domain containing

BRPF1 BRD1 DNMT3A

2.94e-042210831147
GeneFamilyDoublecortin superfamily

DCDC2B DCLK3

1.54e-031010821369
GeneFamilyPHD finger proteins

RSF1 KMT2D BRPF1 BRD1

2.07e-0390108488
GeneFamilyPDZ domain containing

SHROOM3 DVL2 PARD6G GRID2IP AFDN

2.19e-0315210851220
GeneFamilyProtein phosphatases, Mg2+/Mn2+ dependent

PHLPP1 PDP2

4.53e-03171082701
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1A AOC1 TCERG1L ANK2 BEND5 PCDHA12 HARBI1 PPARGC1A PHLPP1 RNF39 RAD54L

1.82e-1019816211d6812494874be0c14361ac2ac3e418b335bb8f55
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FILIP1 STAG1 SYNE1 ARHGAP5 GVINP1 TLE4 ANKRD11 DDX23

3.01e-07178162801dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB4 DOCK4 TCAF2 CYP26B1 SYNE1 PIK3C2A PDIA5 TBCD

5.79e-071941628ad6c04ad0621689e3bf4c94ccd6e60653bbd02c7
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IKZF2 STC1 PPARGC1A RTKN2 AHRR TIGIT

1.79e-06100162660c2bdee5d37dedf9be1e03b6b52b539a2277df3
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IKZF2 STC1 PPARGC1A RTKN2 AHRR TIGIT

1.90e-061011626de49feca7548640f85d206ebc56a58ab0bf7ac16
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB4 DOCK4 TCAF2 SYNE1 CIITA PDIA5 TBCD

3.27e-061721627c056d44e2e130ceccadfcdceb192a7f095d779c8
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 SBNO2 STC1 GPR146 NFKBIA PDIA5 NOTCH1

6.08e-061891627d9c2adbbe3e40eb8d57200b6411533e6685ea0d2
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 SBNO2 STC1 GPR146 NFKBIA PDIA5 NOTCH1

6.08e-061891627476226787c8ea0c9834a6f4c99ac7091cc20a455
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 SBNO2 STC1 GPR146 NFKBIA PDIA5 NOTCH1

6.08e-0618916273fe69bad6427e41b8d2dae450828cc21e9c3b3ad
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK4 FILIP1 SHROOM3 PPARGC1A RTKN2 LLGL2 AFDN

6.29e-06190162730b50d183d7649146eb1e79b47ba897355f1998a
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

ITPR1 AHRR WDR97 CIITA KCNJ6 SLITRK5 PHLPP1

6.97e-06193162708696a99309f5b088692ddac8cca35413b5e810d
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|390C / Donor, Lineage, Cell class and subclass (all cells)

SHROOM3 PEG10 ACOX1 ARHGAP5 RTKN2 LLGL2 STEEP1

7.21e-06194162788db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|390C / Donor, Lineage, Cell class and subclass (all cells)

SHROOM3 PEG10 ACOX1 ARHGAP5 RTKN2 LLGL2 STEEP1

7.21e-061941627a71728202493d4858342ea2756ea281cd0d99a3a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB4 DOCK4 CIITA NFKBIA PDIA5 KCNK6 TBCD

7.21e-061941627fa6d51f36a3dae8763a595c20892987ed454c0f0
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FILIP1 SHROOM3 ANK3 SYNE1 RTKN2 LLGL2 AFDN

7.46e-0619516279406866f99555198a9be311fbd65751b70f35446
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TANC2 IKZF2 ANK3 SYNE1 LPIN1 LLGL2 PDP2

7.97e-061971627e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Stem_cells|GW08 / Sample Type, Dataset, Time_group, and Cell type.

LPIN1 RTKN2 CCNB2 PDP2 PKN1 MAN1B1 RAD54L

8.79e-062001627691b3edf7d8449556e8bf611662eb85772959f0f
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Mesenchymal-Mesoderm|10w / Sample Type, Dataset, Time_group, and Cell type.

TCERG1L PARD6G MON1A HARBI1 LLGL2 GPNMB DNAH9

8.79e-0620016279ef226ebb0a7cdb9431e2fa65faa2a7d67da590d
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Stem_cells-Stem_cells|GW08 / Sample Type, Dataset, Time_group, and Cell type.

LPIN1 RTKN2 CCNB2 PDP2 PKN1 MAN1B1 RAD54L

8.79e-06200162736a110aa91a791fdf1142e7869e8aa0d342402d0
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Stem_cells-Neuroepithelial_cell|GW08 / Sample Type, Dataset, Time_group, and Cell type.

LPIN1 RTKN2 CCNB2 PDP2 PKN1 MAN1B1 RAD54L

8.79e-0620016274e077aa7faddcebdfc54667f8b3990704441005b
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Stem_cells|GW08 / Sample Type, Dataset, Time_group, and Cell type.

LPIN1 RTKN2 CCNB2 PDP2 PKN1 MAN1B1 RAD54L

8.79e-062001627d17ba4239e1fd702a3d757687110f0f2c6f91ef7
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|368C / Donor, Lineage, Cell class and subclass (all cells)

TCAF2 IKZF2 INPP5E RTKN2 TIGIT ABLIM2

1.72e-05148162680470353e12599440f711b6e107730763376d04d
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IKZF2 AICDA SEC31B LACTB RTKN2 TIGIT

2.57e-051591626b05fda31b77536a1878f55d3199563b53f9420b2
ToppCelldroplet-Liver-HEPATOCYTES-1m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 ANK2 SGCB ARHGAP39 CPT1B SURF2

2.66e-051601626a494001b1f6dec33624f98fa3c24bad6988d0425
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

IKZF2 DCDC2B ARHGAP39 TTC34 PPARGC1A CFAP46

2.66e-0516016266de505bfe1fbbe984718740a9cf43d0e02ff452e
ToppCellnormal-na-Lymphocytic_T-T4_reg-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

IKZF2 WHAMM ARHGAP39 SH2D5 RTKN2 TIGIT

2.96e-05163162643887e7687fc6367efac0c1f56a9534b06f47b7f
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB3 BEND5 INPP5E CPT1B CIITA CMTM5

3.62e-051691626d18b823836ca6fba79a2d2f10cb9966fa2623af2
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB3 BEND5 INPP5E CPT1B CIITA CMTM5

3.62e-051691626befb9b1618ea30fbf8983bcc493853da53b809c3
ToppCell390C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ERBB3 SHROOM3 TTC24 TNRC18 WDR97 FUCA1

3.87e-05171162670963f79711fe6088d6d01b29206b17ab89e5e73
ToppCellInfluenza_Severe-B_intermediate|World / Disease group and Cell class

CACNA1A ERBB3 TTC24 ANK2 AICDA POU2AF1

3.87e-0517116264d33e1dc1efc423dbdd5f4cca6d6440a68add8d0
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 FRS3 PARD6G STC1 CCAR2 ABLIM2

4.40e-051751626f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

USP49 ANK3 TNRC18 PIK3C2A MTMR2 CMTM5

4.40e-051751626bb898796662b97f7459b7dda7cecf6a9bde8b055
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

ERBB3 SHROOM3 HELT PEG10 LLGL2 KLC3

4.99e-051791626d5763912a4ce7188535675e338799b856edb9dda
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITPR1 STC1 GPR146 ARHGAP5 DSTYK DCLK3

4.99e-051791626dd94ebe69ade6f51b94058abe066216f0de9feda
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A SHROOM3 LLGL2 KCNJ6 RNF39 KLC3

5.15e-051801626d553aba594f5304f1c09ff9c6d49b64cd7ee7850
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 PARD6G STC1 PDIA5 CCAR2 ABLIM2

5.31e-051811626cef034030e6b029a49ae56be37ea1fac1a5c350e
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANC2 TMEM74 CPT1B STC1 SLC9A3 PDIA5

5.47e-051821626ebc812ed3f25839ea25f76b952c463d79a8325b1
ToppCelldroplet-Heart-nan-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK4 FILIP1 ARHGAP5 GVINP1 PIK3C2A AFDN

5.47e-05182162681279877b920b5a1bc991a07d3031d6458700fe3
ToppCellsevere_influenza-B_intermediate|World / disease group, cell group and cell class (v2)

CACNA1A ANK2 AICDA POU2AF1 C22orf23 CIITA

5.47e-051821626e633a908a2fb30ed362cf22fbb8d6839f31f1751
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANC2 TMEM74 CPT1B STC1 SLC9A3 PDIA5

5.47e-05182162647ff6b4002a4167412c79210651316d1342503f9
ToppCell5'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FILIP1 CYP26B1 GPR146 PPARGC1A KCNK6 RNF39

5.81e-05184162697e97de52daaff8840f4ee76a94ba5e3f79de7ce
ToppCelldroplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANC2 ARHGAP39 RUNX2 RUNX1 LPIN1 GPNMB

5.81e-05184162615ea746c77785120f69f9ab370fb7eb9b70692f8
ToppCellP28-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TANC2 CYP26B1 STC1 NFKBIA PDIA5 NOTCH1

5.81e-0518416268ed22b1af04a711203293e7a8b3df6fb9222fad5
ToppCelldroplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TANC2 ARHGAP39 RUNX2 RUNX1 LPIN1 GPNMB

5.81e-051841626bd5e8fc453a6393b8778734a2c3c2f1281769bcd
ToppCelldroplet-Limb_Muscle-nan-3m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB3 ANK3 RBM12B USP5 DCLK3 CMTM5

5.99e-051851626554c5d812197fbf66bf279fcc953277e926ade15
ToppCelldroplet-Lung-nan-21m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 ARHGAP39 RUNX2 RUNX1 LPIN1 GPNMB

6.17e-051861626f1aa0c58336d23bcbe52a59e7af954d20085bdb6
ToppCelldroplet-Lung-nan-21m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 ARHGAP39 RUNX2 RUNX1 LPIN1 GPNMB

6.17e-0518616268f77e552e613b6e124443c7f6ef5c1316a5ff8db
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 DOCK4 APC ARHGAP5 IGF2 AFDN

6.17e-0518616260ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CACNA1A TCERG1L ANK2 KCNJ6 ASCL4 PNMA6A

6.55e-0518816261f912ea015f50570e848259d948a0ba682d64bb4
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CACNA1A AICDA PCDHA13 PCDHA3 AFDN SRRM3

6.55e-051881626e239bcdbd210a398a5850cb6fbf171d402f45a4f
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PARD6G STC1 GPR146 IGF2 NOTCH1 CFAP46

6.55e-051881626524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PARD6G STC1 GPR146 IGF2 NOTCH1 CFAP46

6.55e-051881626d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB4 DOCK4 TCAF2 PIK3C2A PDIA5 INSYN2B

6.94e-051901626656483751e4bf137e4e4bfb2a03a478a8f7fcb63
ToppCellCOVID-19-Heart-EC_3|Heart / Disease (COVID-19 only), tissue and cell type

EPHB4 DOCK4 STC1 CIITA PIK3C2A TBCD

6.94e-05190162678e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

FILIP1 ERBB3 SHROOM3 ANK3 LLGL2 AFDN

7.15e-051911626d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell(12)_SLC16A7+|World / shred by cell type by condition

TRIM72 DCDC2B LPIN1 TIGIT DNAH9 CFAP46

7.15e-051911626e427eeddd2e87c14376a37db0b43f120c90436bc
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPHB4 CYP26B1 STC1 IGF2 PDIA5 NOTCH1

7.57e-05193162658c590dd6f21bc7ae58ae1729dd574c0f1069592
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Intermediate|GW19 / Sample Type, Dataset, Time_group, and Cell type.

SYNE1 DCDC2B ADCY8 UBR3 MAP2K7

7.77e-051201625eb5b88c47dd4a6f9b55ace24f19d4e81d4ed31e1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB4 TCAF2 CIITA PDIA5 INSYN2B TBCD

7.79e-051941626cf9cf115dbbb9997f7c303ae07f42f3d80ff9a21
ToppCellsevere-B_cell|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

AOC1 PEG10 APC POU2AF1 CMTM5 TRAM2

7.79e-0519416262fee6083fb56b16d1f04fd0b92ec622fd26ba3fa
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_neuro-secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AOC1 TCERG1L DOCK8-AS1 ANK2 ASCL4 RAD54L

7.79e-051941626d024cd75a97f048257e49cee9190fb2e79202ee2
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FILIP1 SHROOM3 ANK3 SYNE1 RTKN2 AFDN

7.79e-05194162653f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell3'_v3-blood-Lymphocytic_NK-NK_CD56bright_CD16-|blood / Manually curated celltypes from each tissue

WHAMM ZCCHC2 LPIN1 NFKBIA ANKRD11 MAP2K7

8.01e-0519516261470f562ebcfe7da367964ecfd6c7f43bcdb4a73
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FILIP1 SYNE1 POU2AF1 DCDC2B DNAH9 CFAP46

8.01e-0519516263486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_1-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TCERG1L HELT PEG10 PCDHA12 RTKN2 KLC3

8.24e-051961626b74dbdfc8d9b85d7cae5c6a49b56347b15ce16e1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB4 DOCK4 CYP26B1 SYNE1 PIK3C2A PDIA5

8.24e-0519616268f2031b1a9232c389517fbf3c29f47f9468b0077
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB4 DOCK4 CYP26B1 SYNE1 PIK3C2A PDIA5

8.24e-05196162648b4a9cea97a55190217deaf51bf867608c5a9a7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB4 DOCK4 CYP26B1 SYNE1 PIK3C2A PDIA5

8.24e-051961626473980c827443464d08a0be28c53e3536369b12a
ToppCellMonocytes-NUPR1+_Monocytes|Monocytes / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

TANC2 DOCK4 SYNE1 GRAMD4 FUCA1 GPNMB

8.47e-0519716268a058c9d9285acd7cf2fb8e34f7602a86b5d6c89
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1A SYNE1 ITPR1 PPARGC1A PKD1 SRRM3

8.71e-051981626c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar-AT1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ERBB3 SHROOM3 PEG10 PCDHA12 RTKN2 LLGL2

8.71e-05198162654228dd9a50616d2022712d162a419ed0327cabd
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

TANC2 DOCK4 SHROOM3 ANK3 STAG1 NF1

8.71e-0519816261996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

TANC2 SHROOM3 RSF1 SBNO1 SEC16A ANKRD11

8.71e-05198162676d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB4 SYNE1 PARD6G STC1 GPR146 IGF2

8.71e-05198162699d6a64f3410dae3019161feef20a8f06081a24b
ToppCellSepsis-Leuk-UTI-Lymphocyte-T/NK-dn_T|Leuk-UTI / Disease, condition lineage and cell class

PEG10 FRS3 POU2AF1 CUL7 GPR146 TIGIT

8.96e-051991626aa4d8ce8994e5032a33d5cc68c482882147cdc3b
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

TANC2 SHROOM3 RSF1 BBX SBNO1 ANKRD11

8.96e-051991626c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-B-B_naive|COVID-19_Mild / Disease, condition lineage and cell class

BEND5 PEG10 SAV1 POU2AF1 ITPR1 CIITA

9.21e-052001626e6a43eff47195e1d39530ad49ad908fc06a8b038
ToppCellLung_Parenchyma-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ERBB3 SHROOM3 ANK3 PEG10 SYNE1 LLGL2

9.21e-052001626c2bde99b3bc7a8740441c1a0c1394892b940b857
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

CACNA1A ANK3 SYNE1 PKD1 ABLIM2 SRRM3

9.21e-05200162648d801219bc771d6c7e151dc88ca4c179988de85
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ERBB3 SHROOM3 ANK3 PEG10 SYNE1 LLGL2

9.21e-0520016263ff9abd5e07780a59d5571da906fa15f00a1d5c2
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW13-Mesenchymal-Mesoderm|GW13 / Sample Type, Dataset, Time_group, and Cell type.

CACNA1A WHAMM DCDC2B LPIN1 LLGL2 SRRM3

9.21e-0520016260f4b8b0868bda406fe6bf01d1b722510fdfd0168
ToppCellsevere-B_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BEND5 PEG10 SAV1 POU2AF1 ITPR1 CIITA

9.21e-0520016260e86f52b6e146d9bbc728d8fb176fc2b53696558
ToppCellmild-B_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BEND5 PEG10 SAV1 POU2AF1 ITPR1 CIITA

9.21e-052001626222789b897e2a683bbfd1d00b6fd8705015d90df
ToppCellsevere-B_naive|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BEND5 PEG10 SAV1 POU2AF1 ITPR1 CIITA

9.21e-052001626306df1f498ac2188eaf9f2a8d002bb73bdb9642d
ToppCellParenchyma_Control_(B.)-Epithelial-TX|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

ERBB3 SHROOM3 ANK3 PEG10 SYNE1 LLGL2

9.21e-0520016269970e9bde6aa2ff3aef60dcb065ff15b7463e147
ToppCellmild-B_naive|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

BEND5 PEG10 SAV1 POU2AF1 ITPR1 CIITA

9.21e-052001626d0467cab6a42bf780aa49046bf3231ca161dc144
ToppCellTCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9

TANC2 RBM12B SYNE1 KMT2D AFDN

1.35e-041351625ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCell(00)_Basal-(3)_72hpi|(00)_Basal / shred by cell type and Timepoint

CMPK1 IKZF2 CCNB2 MINDY1 KLC3

1.40e-041361625d68452500df2f75b803cfd4addb2d15cbcc706f2
ToppCell(08)_Brush+PNEC-(2)_GFP_FOXI1|(08)_Brush+PNEC / shred by cell type by condition

CYP26B1 RSF1 APC SBNO1 ANKRD11

1.50e-041381625817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK8-AS1 ARHGAP5 AHRR AFDN NXF1

1.89e-041451625c0894c738815ff54790caddb4bccfa1503fd555b
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|367C / Donor, Lineage, Cell class and subclass (all cells)

IKZF2 AICDA SEC31B RTKN2 TIGIT

2.01e-04147162547544227faf9b0f107bcf6be92b5f423b50c8e92
ToppCellCiliated_cells-B-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

DCDC2B ARHGAP39 C22orf23 DNAH9 CFAP46

2.14e-0414916256399c5a2f06d79f020dece252526f1c0c110d569
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Fam159b|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TCERG1L PARD6G AHRR GRID2IP INSYN2B

2.14e-04149162598ae408d2d0347865875ff8bbd89d359decea526
ToppCellLeuk-UTI-Lymphocyte-T_NK-dnT|Leuk-UTI / Disease, Lineage and Cell Type

PEG10 FRS3 POU2AF1 TIGIT MINDY1

2.14e-04149162553f145cf7089d948d41aa3c443e983e011826836
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

IKZF2 AICDA LACTB RTKN2 TIGIT

2.89e-041591625ae53ab7a1339007d0b245c6c291ac61e5ff5b682
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ANK2 SYNE1 IGF2 MINDY1 KLC3

2.98e-041601625bb1bb3673059768c0ea0160d29fff127f3a4ecb4
ToppCellPBMC-Severe-cDC_4|Severe / Compartment, Disease Groups and Clusters

TCAF2 AICDA AHRR DNAJC14 GPNMB

2.98e-0416016254dac64e58d9366c399f3d830848ccb720d400be7
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ANK2 SYNE1 IGF2 MINDY1 KLC3

2.98e-04160162576f49b8b4450fa8acd36326bfa36a5d1f4bd95fb
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPARGC1A SLC9A3 BBX GPNMB DNMT3A

3.24e-041631625cab65dabeea58141c649e4fec5e0123beb3de1b3
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_2|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

DCDC2B ARHGAP39 TTC34 PPARGC1A CFAP46

3.43e-041651625731147b4337fd0de4383dc8170b4f9ccd98caec6
DrugCaptopril [62571-86-2]; Up 200; 17.2uM; HL60; HG-U133A

CACNA1A CMPK1 NCAPH2 RUNX1 CPT1B SBNO2 SBNO1 PARP16 MCM3AP MAP2K7

1.29e-06193162101988_UP
Drug(S)-propranolol hydrochloride [4199-10-4]; Up 200; 13.6uM; HL60; HT_HG-U133A

EPHB4 CACNA1A ANK3 BEND5 PEG10 FRS3 NCAPH2 RUNX1 AFDN MAP2K7

1.48e-06196162102961_UP
DiseaseProfound Mental Retardation

STAG1 INPP5E APC CHD8 NF1 MAN1B1 RAI1 TBCD DNMT3A

5.22e-081391549C0020796
DiseaseMental Retardation, Psychosocial

STAG1 INPP5E APC CHD8 NF1 MAN1B1 RAI1 TBCD DNMT3A

5.22e-081391549C0025363
DiseaseMental deficiency

STAG1 INPP5E APC CHD8 NF1 MAN1B1 RAI1 TBCD DNMT3A

5.22e-081391549C0917816
DiseaseIntellectual Disability

TANC2 STAG1 INPP5E SYNE1 APC CHD8 NF1 FUCA1 MAN1B1 RAI1 TBCD DNMT3A

4.35e-0644715412C3714756
Diseasetotal blood protein measurement

AOC1 STAG1 INPP5E POU2AF1 RUNX1 KMT2D BBX TLE4 NFKBIA PKD1 SEC16A AFDN

4.55e-0644915412EFO_0004536
Disease1,5 anhydroglucitol measurement

PCDHA13 PCDHA12 PCDHA3 PCDHA2

1.53e-05291544EFO_0008009
DiseaseMammary Carcinoma, Human

EPHB4 ERBB3 SYNE1 KMT2D LLGL2 NFKBIA GPNMB MAP2K7 CTU1 NOTCH1 RAD54L DNMT3A

2.16e-0552515412C4704874
DiseaseMammary Neoplasms, Human

EPHB4 ERBB3 SYNE1 KMT2D LLGL2 NFKBIA GPNMB MAP2K7 CTU1 NOTCH1 RAD54L DNMT3A

2.16e-0552515412C1257931
DiseaseMammary Neoplasms

EPHB4 ERBB3 SYNE1 KMT2D LLGL2 NFKBIA GPNMB MAP2K7 CTU1 NOTCH1 RAD54L DNMT3A

2.24e-0552715412C1458155
DiseaseBreast Carcinoma

EPHB4 ERBB3 SYNE1 KMT2D LLGL2 NFKBIA GPNMB MAP2K7 CTU1 NOTCH1 RAD54L DNMT3A

2.75e-0553815412C0678222
Diseasepulse pressure measurement

EPHB4 SHROOM3 ANK2 ACOX1 TMEM74 TRIOBP PCDHA13 PCDHA12 PCDHA3 PCDHA2 ZCCHC2 LACTB PPARGC1A PIK3C2A NFKBIA MYPN PKD1 ANKRD11 UBR3 BRD1

3.99e-05139215420EFO_0005763
Diseaseneuroimaging measurement

ERBB3 SHROOM3 ANK3 STAG1 APC RUNX2 TTC34 SH2D5 PPARGC1A IGF2 NF1 SBNO1 DSTYK TLE4 PKD1 MTMR2 RAI1

4.61e-05106915417EFO_0004346
DiseaseMalignant neoplasm of breast

EPHB4 ERBB3 ANK2 SYNE1 TRMT10A KMT2D LLGL2 NF1 SBNO1 NFKBIA GPNMB MAP2K7 DNAH9 CTU1 NOTCH1 RAD54L DNMT3A

4.88e-05107415417C0006142
DiseaseGiant Cell Glioblastoma

APC RUNX1 NF1 NFKBIA NOTCH1

8.04e-05841545C0334588
Diseaselung non-small cell carcinoma (is_implicated_in)

CMPK1 ERBB3 ERCC5 RUNX2 KMT2D MAP2K7

9.30e-051391546DOID:3908 (is_implicated_in)
DiseaseJuvenile Myelomonocytic Leukemia

RUNX1 NF1 DNMT3A

1.27e-04191543C0349639
DiseaseAdenocarcinoma of large intestine

APC TBCK DCLK3 PKN1 MAP2K7

1.51e-04961545C1319315
Diseasenon-obstructive coronary artery disease

PHLPP1 RNF39

1.61e-0441542EFO_1001483
DiseaseNasopharyngeal carcinoma

ERBB3 SYNE1 NFKBIA

2.00e-04221543C2931822
Diseasecortical surface area measurement

TANC2 CACNA1A FILIP1 ERBB3 SHROOM3 ANK3 STAG1 INPP5E APC TRIOBP ARHGAP39 TTC34 IGF2 DSTYK TLE4 PKD1 MTMR2 BRD1

2.39e-04134515418EFO_0010736
Diseasevital capacity

FILIP1 SHROOM3 AOC1 CYP26B1 SYNE1 TMEM74 PCDHA13 PCDHA12 PCDHA3 PCDHA2 RUNX2 ADCY8 ITPR1 LLGL2 KCNJ6 MYPN CCAR2

2.62e-04123615417EFO_0004312
Diseasecystatin C measurement

SHROOM3 LACTB STC1 PPARGC1A USP5 IGF2 PIK3C2A ANKRD11 MINDY1

2.76e-044021549EFO_0004617
DiseaseHepatoblastoma

APC IGF2

4.00e-0461542C0206624
Diseasenormal

NCAPH2 AHRR

4.00e-0461542PATO_0000461
Diseasehearing loss

DVL2 TRIOBP NCAPH2 AHRR

4.24e-04671544EFO_0004238
Diseasebipolar disorder (is_implicated_in)

ANK3 SYNE1 BRD1

4.61e-04291543DOID:3312 (is_implicated_in)
Diseaseable to hear with hearing aids

FILIP1 AHRR

5.59e-0471542EFO_0009720
Diseasebrain infarction (biomarker_via_orthology)

IGF2 KCNK6 GPNMB

6.78e-04331543DOID:3454 (biomarker_via_orthology)
Diseasesexual dimorphism measurement

USP49 FILIP1 AOC1 INPP5E TMEM74 FRS3 APC MON1A ADCY8 IGF2 NF1 PKD1 SEC16A ANKRD11 DNMT3A

7.05e-04110615415EFO_0021796
Diseasemenstrual cycle measurement

IGF2 NOTCH1

7.42e-0481542EFO_0007786
DiseaseGlioblastoma

APC RUNX1 NF1 NOTCH1

7.91e-04791544C0017636
Diseaseendometrial cancer (is_marker_for)

APC RUNX1 NOTCH1

8.07e-04351543DOID:1380 (is_marker_for)
Diseaseneuroticism measurement, cognitive function measurement

STAG1 APC PCDHA13 PCDHA12 PCDHA3 PCDHA2 ADCY8 BBX MTMR2 RAI1

8.13e-0456615410EFO_0007660, EFO_0008354
DiseaseGrowth Disorders

IGF2 RAI1 DNMT3A

8.77e-04361543C0018273
Diseaseneutrophil count

SEMA6C CACNA1A INPP5E PCDHA13 PCDHA12 PCDHA3 PCDHA2 MON1A ZCCHC2 SBNO2 BBX SBNO1 DSTYK PKD1 ANKRD11 FGB MTRF1L

9.22e-04138215417EFO_0004833
Diseasehemangiopericytoma (is_marker_for)

EPHB4 NOTCH1

9.51e-0491542DOID:264 (is_marker_for)
DiseaseAutism Spectrum Disorders

CHD8 ANKRD11 RAI1 DNMT3A

1.04e-03851544C1510586
Diseasevisceral adipose tissue measurement, body mass index

PCDHA13 PCDHA12 PCDHA3 PCDHA2

1.13e-03871544EFO_0004340, EFO_0004765
Diseaseserum albumin measurement

DOCK4 SHROOM3 AOC1 SAV1 ZCCHC2 RUNX1 ANKRD54 BBX CIITA SBNO1

1.14e-0359215410EFO_0004535
DiseaseFacies

CHD8 DNMT3A

1.18e-03101542C0282631
DiseaseColorectal Carcinoma

TCERG1L ANK2 SYNE1 APC ADCY8 LPIN1 ZNHIT6 IGF2 NF1 MCM3AP GPNMB

1.19e-0370215411C0009402
DiseaseEczema

ERBB3 IKZF2 RUNX1 TLE4 NFKBIA RAI1 DNMT3A

1.26e-033101547HP_0000964
Diseasetotal hip arthroplasty, osteoarthritis

FILIP1 TRIOBP RUNX2

1.38e-03421543EFO_0009806, MONDO_0005178
Diseasekidney cancer (implicated_via_orthology)

SAV1 LLGL2

1.44e-03111542DOID:263 (implicated_via_orthology)
DiseaseNeurodevelopmental Disorders

TANC2 ANK2 ITPR1 ANKRD11

1.45e-03931544C1535926
Diseaseintracranial aneurysm (is_implicated_in)

KMT2D PKD1

1.73e-03121542DOID:10941 (is_implicated_in)
Diseasecalcium measurement

ERCC5 CHD8 ZCCHC2 DMAP1 ITPR1 BBX TLE4 KCNK6 MINDY1 DNMT3A

1.76e-0362815410EFO_0004838
DiseaseConnective Tissue Diseases

PKD1 NOTCH1

2.03e-03131542C0009782
Disease5-methyluridine (ribothymidine) measurement

NCAPH2 CPT1B

2.36e-03141542EFO_0020013
DiseaseSchizophrenia

DOCK4 ERBB3 ANK3 APC SBNO2 PPARGC1A RTKN2 IGF2 SBNO1 BRD1 MAP2K7 RAI1

2.38e-0388315412C0036341
DiseaseStreptozotocin Diabetes

ACOX1 CPT1B PPARGC1A SLC9A3

2.51e-031081544C0038433
DiseaseDiabetes Mellitus, Experimental

ACOX1 CPT1B PPARGC1A SLC9A3

2.51e-031081544C0011853
DiseaseAlloxan Diabetes

ACOX1 CPT1B PPARGC1A SLC9A3

2.51e-031081544C0002152
DiseaseAutistic Disorder

DOCK4 APC CHD8 CUL7 IGF2 NF1

2.55e-032611546C0004352
DiseaseChildhood Acute Lymphoblastic Leukemia

IKZF2 RUNX1 NOTCH1

2.55e-03521543C0023452
DiseaseNeoplasm of uncertain or unknown behavior of bladder

ERBB3 NOTCH1

2.72e-03151542C0496930
DiseaseSitus ambiguus

SHROOM3 DNAH9

2.72e-03151542C0266642
DiseaseBenign neoplasm of bladder

ERBB3 NOTCH1

2.72e-03151542C0154017
DiseaseCarcinoma in situ of bladder

ERBB3 NOTCH1

2.72e-03151542C0154091
DiseaseGlioblastoma Multiforme

APC RUNX1 NF1 NOTCH1

2.77e-031111544C1621958
Diseaseendometriosis (biomarker_via_orthology)

RUNX1 NFKBIA

3.10e-03161542DOID:289 (biomarker_via_orthology)
DiseaseHuntington's disease (biomarker_via_orthology)

ITPR1 PPARGC1A

3.10e-03161542DOID:12858 (biomarker_via_orthology)
Diseasebasal cell carcinoma

INPP5E SBNO2 DSTYK SEC16A ANKRD11

3.20e-031891545EFO_0004193
DiseaseBenign neoplasm of stomach

ERBB3 APC

3.50e-03171542C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

ERBB3 APC

3.50e-03171542C0496905
Diseasemuscular dystrophy (is_implicated_in)

SGCB SYNE1

3.50e-03171542DOID:9884 (is_implicated_in)
DiseaseCarcinoma in situ of stomach

ERBB3 APC

3.50e-03171542C0154060
Diseaserespiratory symptom change measurement, response to placebo

ADCY8 PPARGC1A

3.50e-03171542EFO_0008344, EFO_0010068
DiseaseAcute myeloid leukemia

RUNX1 DNMT3A

3.50e-03171542cv:C0023467
DiseaseLEUKEMIA, ACUTE MYELOID

RUNX1 DNMT3A

3.50e-03171542601626
DiseaseMalignant neoplasm of skin

ERBB3 CSNK2A1 NOTCH1

3.66e-03591543C0007114
DiseaseSkin Neoplasms

ERBB3 CSNK2A1 NOTCH1

3.66e-03591543C0037286
DiseaseBipolar Disorder

CACNA1A ERBB3 ANK3 SYNE1 ZCCHC2 ADCY8 ITPR1 BRD1

3.69e-034771548C0005586
DiseaseCarcinoma of bladder

ERBB3 NOTCH1

3.92e-03181542C0699885
Diseasecutaneous melanoma, hair color

DOCK8-AS1 DSTYK DNMT3A

4.21e-03621543EFO_0000389, EFO_0003924
Diseaseosteoporosis (implicated_via_orthology)

IGF2 CIITA

4.37e-03191542DOID:11476 (implicated_via_orthology)
DiseaseC-reactive protein measurement

SEMA6C DOCK4 ANK3 MON1A ZCCHC2 ADCY8 ITPR1 SBNO1 DSTYK KCNJ6 TLE4 PKD1 SEC16A ASCL4

4.38e-03120615414EFO_0004458
DiseaseObesity

CYP26B1 INPP5E LACTB IGF2 RAI1

4.52e-032051545C0028754
DiseaseOsteoarthritis of hip

FILIP1 RUNX2

4.83e-03201542C0029410
Diseasedilated cardiomyopathy

PKD1 GPNMB

4.83e-03201542EFO_0000407
Diseasewaist-hip ratio

ANK3 RUNX1 ADCY8 STC1 RTKN2 IGF2 BBX CIITA CSNK2A1 DSTYK KCNJ6 PKD1 ASCL4 DNMT3A

5.06e-03122615414EFO_0004343

Protein segments in the cluster

PeptideGeneStartEntry
EEDLQLRHIKRPEGR

BEND5

111

Q7L4P6
PSKRHRDRLNAELDH

AHRR

36

A9YTQ3
HGIVEDRRPKERISF

CCAR2

521

Q8N163
IESPSRELAAHLRRK

C2orf16

1311

Q68DN1
VHVSGERRLDIDEKP

AFDN

96

P55196
DLRSGDKLRREHIKP

ADCY8

676

P40145
EEGPEDKAERRARHR

CACNA1A

966

O00555
DKAERRARHREGSRP

CACNA1A

971

O00555
GPTEERLDIKHNRPR

ERBB3

476

P21860
GKPALVRRHTLEDRS

BRD1

876

O95696
GRPDDKAIAAEHRVL

CHD8

1661

Q9HCK8
RRDGRAKPEEAHREE

ANKRD11

961

Q6UB99
RVDALDRAGRTPLHL

ANKRD54

201

Q6NXT1
EHPRLDNRGATKILA

BBX

101

Q8WY36
RLLHDARPKEGDDRP

DNMT3A

736

Q9Y6K1
GLAEVLLAAKEHRRP

CIITA

396

P33076
HTPDDPLLRGKRRQD

GVINP1

6

Q7Z2Y8
RGHKRDDFLDLAESP

GRAMD4

11

Q6IC98
RLPLDAAKRFHDVLG

GPNMB

16

Q14956
CEDRKAEPEGLRRLH

AICDA

116

Q9GZX7
IRSLRRDHKPSKEEG

ANKRD13C

6

Q8N6S4
RLEPATEHLRKAARL

CFAP46

441

Q8IYW2
AAPEEHCRRGEDLKR

CFAP46

2016

Q8IYW2
KDVDRTRLERHLSPE

ABLIM2

566

Q6H8Q1
LDKGERHPVREARAV

AOC1

86

P19801
DDAVRVLRDIVHKPG

DVL2

331

O14641
LRKAVEEARHPDLQG

ATG4C

241

Q96DT6
EKKRSGSLERDRPGH

RBM12B

371

Q8IXT5
KSLRSRRVHRGLPEA

RAI1

996

Q7Z5J4
EDARAAKHARGRLVL

RBM15

226

Q96T37
KRRLPEESGGRHLDR

RBM15

641

Q96T37
KRAGVRRALHDPLEK

RAD54L

101

Q92698
DRRAKADPLHVALEV

ARHGAP39

756

Q9C0H5
PRLFRVASKRHGDLL

PCDHA2

61

Q9Y5H9
GRTARLLSERDAAKH

PCDHB18P

571

Q96TA0
ARLEGPHEARLRAEL

KCNK6

26

Q9Y257
VRLPALHIAARKDDT

ANK2

191

Q01484
DIDHRRSEELRKGLA

C22orf23

201

Q9BZE7
RQRHRFPTKEDTREG

DNAJC14

196

Q6Y2X3
PRLFRVASKRHGDLL

PCDHA3

61

Q9Y5H8
GREEELRKHPIKRAA

NOTCH1

1621

P46531
HSADFPRGREKAELL

HELT

66

A6NFD8
SRRLGALRVHDPLED

MAGEE2

76

Q8TD90
RPGHDPVRERLKRDL

LLGL2

6

Q6P1M3
VAAEHLTRKRPGAEA

EPHB4

141

P54760
ARPRLERALSLDDKG

INPP5E

76

Q9NRR6
PLRQLEDHKRGEALR

ITPR1

1731

Q14643
ARDDLPRHISRDRTK

KCNJ6

36

P48051
PTVLEKLRDELRAHG

CYP26B1

316

Q9NR63
SRDLLHRIKDEVGAP

LACTB

111

P83111
LKRKEDQDRSPRRHG

MCM3AP

291

O60318
SHVDIRRLLPDKDGA

LOXHD1

1186

Q8IVV2
VGHLAREDRFIPKRE

LOXHD1

1876

Q8IVV2
SKPPREATLEERHAR

DCLK3

106

Q9C098
GRGHRTLDRFKLDDV

HARBI1

16

Q96MB7
FSARGHRPLDKKREE

FGB

41

P02675
IRERFPKLLRLDGHE

NXF1

341

Q9UBU9
HRDVKPSNILLDERG

MAP2K7

241

O14733
FHPLLRDEKAEGIAR

PIK3C2A

1531

O00443
KGTLRRHDDRPQVLS

CUL7

1631

Q14999
HRDLVGELGTALRKR

FUCA1

161

P04066
HIERRLARAAAARKP

PEG10

236

Q86TG7
RPAGERRQRPKHESD

MINDY1

451

Q8N5J2
PSRKRDKRSRHLGAD

LPIN1

381

Q14693
LRFAHKPEGRTRRSI

MTMR2

161

Q13614
RGKKEAEDELSARHP

LONP1

241

P36776
PRDGLKKERLLDDRH

NFKBIA

16

P25963
RALEIREKVLGADHP

KLC3

316

Q6P597
GHRRDKDRKRSSLSP

DDX23

96

Q9BUQ8
DRKPLSREDEIRGHD

IKZF2

61

Q9UKS7
RKDHAPRLARLSLES

DSTYK

626

Q6XUX3
GRRDVEVKPADRHNL

MAN1B1

581

Q9UKM7
LRDEGPRRRAHLDIG

PARD6G

121

Q9BYG4
PRLFRVASKRHGDLL

PCDHA13

61

Q9Y5I0
DRRRARIKHSEGGDI

PARP16

236

Q8N5Y8
GGHEERKTKRPSLRL

PPARGC1A

366

Q9UBK2
RKTKRPSLRLFGDHD

PPARGC1A

371

Q9UBK2
EPVKELLRRKRGHAS

POU2AF1

26

Q16633
KRGAHLALREALRTP

MON1A

516

Q86VX9
ELSRLKREHPESEDR

PDP2

316

Q9P2J9
HGIKRRDRSPSRLDT

CEP135

431

Q66GS9
HILDGSPEKTRRRRE

ACOX1

21

Q15067
DPRFNDILGRHSRKR

CSNK2A3

266

Q8NEV1
ELLRLAGRKRPDAVH

GRID2IP

116

A4D2P6
RADDRRPLRAGRKLH

DOCK8-AS1

251

Q5T8R8
LSHPEDGEKIARLRE

DOCK4

1531

Q8N1I0
PLHFLRRASKAGEVD

CCNB2

266

O95067
TDLKIPVFDAGHERR

DMAP1

211

Q9NPF5
APHRRKETAGALEVA

DCDC2B

291

A2VCK2
RALPRDDGTARKTRH

FRS3

471

O43559
PEAFRGHARDLLKRL

CTU1

241

Q7Z7A3
GHARDLLKRLEAARP

CTU1

246

Q7Z7A3
PALLRARRGHVLAKE

IGF2

131

P01344
RTADHISRDAFLKRP

ZNHIT6

286

Q9NWK9
VRLPALHIAARKDDT

ANK3

201

Q12955
DPRFNDILGRHSRKR

CSNK2A1

266

P68400
LEHRRVAAAARGPLD

HAS1

76

Q92839
RDHLPRELADKRLSK

ASCL4

96

Q6XD76
HLSAGELLRDERKNP

CMPK1

31

P30085
GKRESLLSLDDRHDR

DNAH9

831

Q9NYC9
DRDTGRLEPSAHRLL

GPR146

221

Q96CH1
EEGKPSRKRLHRIET

RSF1

1291

Q96T23
RHGPEPERTRAELEK

SAMD1

61

Q6SPF0
KRLESLGALTHGDRR

SBNO1

1011

A3KN83
PDGVDFRLSREALKH

CPT1B

16

Q92523
IRALREGDHERLGKK

PDIA5

501

Q14554
HKLDQLDASRGRAIP

PKD1

3096

P98161
PRLFRVASKRHGDLL

PCDHA12

61

Q9UN75
DGPREPRRHRQKLDD

RUNX1

171

Q01196
VDGPREPRRHRQKLD

RUNX2

221

Q13950
KLLPARRNRLSDGEH

RTKN2

561

Q8IZC4
RPRDRSRVIDAAKHA

STEEP1

51

Q9H5V9
AAEPGLVKRAHREIL

SRRM3

41

A6NNA2
LPDRGHEELRKLEST

SYNE1

1306

Q8NF91
ERERRIKAHLGKGAP

TCAF2

806

A6NFQ2
GSAEPEKVLRVLHRD

FILIP1

116

Q7Z7B0
EVRKRCESAEPRHGE

PRPF6

896

O94906
AGSEAHLKVRRPELL

MTRF1L

51

Q9UGC7
LPGEEANSRFRHRDK

GPRASP2

341

Q96D09
REPRLNEKLHGRAFD

SLC9A3

471

P48764
KELPESEGRARHARL

SH2D5

211

Q6ZV89
DRKDRLPLESAVVRH

ERCC5

496

P28715
RKAAPDLGSHLDRQV

SHROOM3

706

Q8TF72
RRGVLEPLENLHKER

TANC2

516

Q9HCD6
KRLESLGALTHGDRR

SBNO2

871

Q9Y2G9
DEVLASLRHGRAPLR

WHAMM

711

Q8TF30
GDVRAFLREHPSLRL

SURF2

6

Q15527
DHPKGRLLREELAAA

PKN1

281

Q16512
TKRKGRHRGSEEDPL

ARHGAP5

1186

Q13017
RDPSLDLKHRGVLSA

SEC31B

51

Q9NQW1
PIDEDRLHKTGLRGR

SGCB

46

Q16585
ARLPRKDPAGHRDDL

TRIOBP

1591

Q9H2D6
TRAHLTEPLDEALRK

PNMA6A

291

P0CW24
LRNLRGEEDSPSHIK

STC1

226

P52823
RKLAHQRETGRDGPE

BRPF1

821

P55201
IHSQPDDKRGRREIR

APC

391

P25054
MLSARDRRDRHPEEG

CMTM5

1

Q96DZ9
ADHADSRRLRRKGPS

NCAPH2

371

Q6IBW4
GSLKREERRHPDLEP

ZCCHC2

421

Q9C0B9
RGDLNRIIEDPPHKR

TCERG1L

376

Q5VWI1
DGQRKRPLGDRAHED

SAV1

141

Q9H4B6
LRESKELADLARLHP

TNRC18

751

O15417
LLLRAHPEEKAQGRR

TTC24

101

A2A3L6
RREHSAFGDRPEKRD

SEC16A

1301

O15027
TPFRLHGRDLDEVSK

SLITRK5

266

O94991
AHSPRENGLDKTRLL

TLE4

271

Q04727
RAELRAARLTHGLEP

WDR97

86

A6NE52
RLPARLIKRESGYHE

TRAM2

336

Q15035
RKSARLLLHTPRDAG

USP49

206

Q70CQ1
DHEELLRTPGASLRK

NF1

646

P21359
RAHRRRGKDIETPGL

SEMA6C

631

Q9H3T2
SRHDPQAEEALAKRR

STAG1

441

Q8WVM7
LKAFLELRTVDGPRH

TMEM168

481

Q9H0V1
RIHSVEGDLRRKSAG

TIGIT

171

Q495A1
LEAHVEAKEPRALRS

TRIM72

391

Q6ZMU5
DELLSSPEGHAKFRR

TBCK

516

Q8TEA7
PDGIRHIRADKRVNE

SF3B3

521

Q15393
AASLRHRGREVGKDL

nan

116

Q86TA4
AHGEEDRDLRRGKPL

UBR3

1841

Q6ZT12
RDAVLSRIPEHKSDR

TTC7B

341

Q86TV6
HGETTRRLEAEEKPL

PHLPP1

476

O60346
HRGELEKLFPRSDVA

TBCD

941

Q9BTW9
EPNSDGHDRKRVRRD

TRMT10A

81

Q8TBZ6
RLEKESARLGAHLDR

TMEM74

216

Q96NL1
VDPDHRGLKRLKARI

TTC34

541

A8MYJ7
LHLRRTRRPKEEDPA

USP5

71

P45974
SRELREKLAEPGARA

RNF39

156

Q9H2S5
LRLAQHLEDGPRRVK

INSYN2B

151

A6NMK8
GDIARKTDRPALHLR

KMT2D

2091

O14686
SHRGRSRVQERDKEP

MYPN

1051

Q86TC9