Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	GABA receptor binding	GABRG1 GABARAP GABARAPL1 PLCL2 GABARAPL3	7.69e-08	20	113	5	GO:0050811
GeneOntologyMolecularFunction	phosphatidylethanolamine binding	GABARAP GABARAPL1 GABARAPL3	1.60e-04	19	113	3	GO:0008429
GeneOntologyBiologicalProcess	cellular response to nitrogen levels	GABARAP GABARAPL1 GABARAPL3	3.67e-05	12	116	3	GO:0043562
GeneOntologyBiologicalProcess	cellular response to nitrogen starvation	GABARAP GABARAPL1 GABARAPL3	3.67e-05	12	116	3	GO:0006995
GeneOntologyBiologicalProcess	negative regulation of intracellular steroid hormone receptor signaling pathway	VPS11 ESR2 PIAS2 CLOCK	7.42e-05	40	116	4	GO:0033144
GeneOntologyBiologicalProcess	meiotic spindle assembly checkpoint signaling	TTK KNL1	9.37e-05	3	116	2	GO:0033316
GeneOntologyBiologicalProcess	epithelial cell development	FLNB ESR2 CLOCK HEG1 ADIPOQ MUC2 ADAMTSL4 HYDIN	1.42e-04	269	116	8	GO:0002064
GeneOntologyBiologicalProcess	meiotic spindle checkpoint signaling	TTK KNL1	1.87e-04	4	116	2	GO:0044779
GeneOntologyBiologicalProcess	protein localization to cell junction	PCLO DAG1 GABARAP LSR CACNG7 HEG1	1.91e-04	148	116	6	GO:1902414
GeneOntologyBiologicalProcess	mitotic spindle assembly checkpoint signaling	INCENP APC TTK KNL1	1.94e-04	51	116	4	GO:0007094
GeneOntologyBiologicalProcess	spindle assembly checkpoint signaling	INCENP APC TTK KNL1	1.94e-04	51	116	4	GO:0071173
GeneOntologyBiologicalProcess	negative regulation of mitotic metaphase/anaphase transition	INCENP APC TTK KNL1	2.25e-04	53	116	4	GO:0045841
GeneOntologyBiologicalProcess	negative regulation of mitotic sister chromatid segregation	INCENP APC TTK KNL1	2.25e-04	53	116	4	GO:0033048
GeneOntologyBiologicalProcess	negative regulation of sister chromatid segregation	INCENP APC TTK KNL1	2.25e-04	53	116	4	GO:0033046
GeneOntologyBiologicalProcess	negative regulation of mitotic sister chromatid separation	INCENP APC TTK KNL1	2.25e-04	53	116	4	GO:2000816
GeneOntologyBiologicalProcess	mitotic spindle checkpoint signaling	INCENP APC TTK KNL1	2.25e-04	53	116	4	GO:0071174
GeneOntologyBiologicalProcess	negative regulation of metaphase/anaphase transition of cell cycle	INCENP APC TTK KNL1	2.60e-04	55	116	4	GO:1902100
GeneOntologyBiologicalProcess	negative regulation of chromosome separation	INCENP APC TTK KNL1	2.60e-04	55	116	4	GO:1905819
GeneOntologyBiologicalProcess	spindle checkpoint signaling	INCENP APC TTK KNL1	2.98e-04	57	116	4	GO:0031577
GeneOntologyBiologicalProcess	negative regulation of chromosome segregation	INCENP APC TTK KNL1	2.98e-04	57	116	4	GO:0051985
GeneOntologyBiologicalProcess	process utilizing autophagic mechanism	ATP6V1B1 STAM2 VPS11 GABARAP STAM ACVR2A GABARAPL1 RAB3GAP2 CLTC GABARAPL3 FOXK1 PINK1	3.01e-04	650	116	12	GO:0061919
GeneOntologyBiologicalProcess	autophagy	ATP6V1B1 STAM2 VPS11 GABARAP STAM ACVR2A GABARAPL1 RAB3GAP2 CLTC GABARAPL3 FOXK1 PINK1	3.01e-04	650	116	12	GO:0006914
GeneOntologyBiologicalProcess	negative regulation of metaphase/anaphase transition of meiotic cell cycle	TTK KNL1	3.10e-04	5	116	2	GO:1902103
GeneOntologyBiologicalProcess	negative regulation of meiotic chromosome separation	TTK KNL1	3.10e-04	5	116	2	GO:1905133
GeneOntologyBiologicalProcess	regulation of mitotic sister chromatid segregation	INCENP APC TTK KNL1	3.63e-04	60	116	4	GO:0033047
GeneOntologyBiologicalProcess	regulation of metaphase/anaphase transition of meiotic cell cycle	TTK KNL1	4.63e-04	6	116	2	GO:1902102
GeneOntologyBiologicalProcess	regulation of meiotic chromosome separation	TTK KNL1	4.63e-04	6	116	2	GO:1905132
GeneOntologyBiologicalProcess	regulation of extracellular exosome assembly	STAM SDCBP	4.63e-04	6	116	2	GO:1903551
GeneOntologyBiologicalProcess	hormone-mediated signaling pathway	VPS11 ESR2 TSHR PIAS2 CLOCK RXRG NCOA1	4.65e-04	244	116	7	GO:0009755
GeneOntologyBiologicalProcess	negative regulation of mitotic nuclear division	INCENP APC TTK KNL1	4.65e-04	64	116	4	GO:0045839
GeneOntologyBiologicalProcess	regulation of mitotic sister chromatid separation	INCENP APC TTK KNL1	4.65e-04	64	116	4	GO:0010965
GeneOntologyBiologicalProcess	establishment of protein localization to vacuole	STAM2 STAM AP3M1 CACNG7	5.23e-04	66	116	4	GO:0072666
GeneOntologyBiologicalProcess	mitotic sister chromatid separation	INCENP APC TTK KNL1	5.54e-04	67	116	4	GO:0051306
GeneOntologyCellularComponent	ribbon synapse	PCLO DAG1 OTOF CLTC	2.97e-05	32	117	4	GO:0097470
GeneOntologyCellularComponent	ESCRT-0 complex	STAM2 STAM	9.28e-05	3	117	2	GO:0033565
Domain	Atg8	GABARAP GABARAPL1 GABARAPL3	1.25e-05	8	115	3	PF02991
Domain	Atg8-like	GABARAP GABARAPL1 GABARAPL3	1.25e-05	8	115	3	IPR004241
Domain	Aspartic_peptidase_A1	BACE1 PGC CTSE	2.64e-05	10	115	3	IPR001461
Domain	PEPTIDASE_A1	BACE1 PGC CTSE	2.64e-05	10	115	3	IPR033121
Domain	Asp	BACE1 PGC CTSE	2.64e-05	10	115	3	PF00026
Domain	PEPTIDASE_A1	BACE1 PGC CTSE	2.64e-05	10	115	3	PS51767
Domain	-	BACE1 PGC CTSE	4.80e-05	12	115	3	2.40.70.10
Domain	ASP_PROTEASE	BACE1 PGC CTSE	4.80e-05	12	115	3	PS00141
Domain	Aspartic_peptidase_AS	BACE1 PGC CTSE	6.22e-05	13	115	3	IPR001969
Domain	Peptidase_aspartic_dom	BACE1 PGC CTSE	1.45e-04	17	115	3	IPR021109
Domain	Clathrin	VPS11 CLTC	7.74e-04	7	115	2	PF00637
Domain	Aspartic_peptidase_N	PGC CTSE	7.74e-04	7	115	2	IPR012848
Domain	CHCR	VPS11 CLTC	7.74e-04	7	115	2	PS50236
Domain	A1_Propeptide	PGC CTSE	7.74e-04	7	115	2	PF07966
Domain	PAS	KCNH7 CLOCK NCOA1	9.90e-04	32	115	3	SM00091
Domain	Clathrin_H-chain/VPS_repeat	VPS11 CLTC	1.03e-03	8	115	2	IPR000547
Domain	PAS	KCNH7 CLOCK NCOA1	1.18e-03	34	115	3	PS50112
Domain	PAS	KCNH7 CLOCK NCOA1	1.18e-03	34	115	3	IPR000014
Domain	VHS	STAM2 STAM	1.32e-03	9	115	2	PS50179
Domain	VHS	STAM2 STAM	1.32e-03	9	115	2	PF00790
Domain	VHS	STAM2 STAM	1.32e-03	9	115	2	SM00288
Domain	VHS_dom	STAM2 STAM	1.32e-03	9	115	2	IPR002014
Domain	ITAM_1	STAM2 STAM	1.64e-03	10	115	2	PS51055
Domain	Phos_immunorcpt_sig_ITAM	STAM2 STAM	1.64e-03	10	115	2	IPR003110
Domain	C8	MUC19 MUC2	2.38e-03	12	115	2	PF08742
Domain	TIL	MUC19 MUC2	2.38e-03	12	115	2	PF01826
Domain	PDZ	PCLO CNKSR2 TAX1BP3 SDCBP AHNAK2	2.43e-03	151	115	5	PS50106
Domain	PDZ	PCLO CNKSR2 TAX1BP3 SDCBP AHNAK2	2.50e-03	152	115	5	IPR001478
Domain	Unchr_dom_Cys-rich	MUC19 MUC2	2.80e-03	13	115	2	IPR014853
Domain	C8	MUC19 MUC2	2.80e-03	13	115	2	SM00832
Domain	TIL_dom	MUC19 MUC2	3.26e-03	14	115	2	IPR002919
Domain	K_chnl_volt-dep_EAG/ELK/ERG	KCNH7 HCN1	3.26e-03	14	115	2	IPR003938
Domain	VWF_type-D	MUC19 MUC2	4.26e-03	16	115	2	IPR001846
Domain	VWFD	MUC19 MUC2	4.26e-03	16	115	2	PS51233
Domain	VWD	MUC19 MUC2	4.26e-03	16	115	2	SM00216
Domain	VWD	MUC19 MUC2	4.26e-03	16	115	2	PF00094
Domain	UIM	STAM2 STAM	5.39e-03	18	115	2	PF02809
Domain	CTCK_1	MUC19 MUC2	5.39e-03	18	115	2	PS01185
Domain	Cadherin-like	PCDHGA11 DAG1 CELSR1 PCDHB1	5.75e-03	116	115	4	IPR015919
Domain	VWC_out	MUC19 MUC2	6.00e-03	19	115	2	SM00215
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	HIVEP1 ILF3 MARS1 INPP5D CHD9 QRICH1 SIN3A ACTN1 UBN2 RAB3GAP2 CLTC NCOA1 ELF1 CDC73 LRIF1 SDCBP FOXK1 KNL1	3.16e-08	1103	117	18	34189442
Pubmed	Widespread macromolecular interaction perturbations in human genetic disorders.	STAM2 ESR2 NCF2 ACTN1 PIAS2 RXRG ADIPOQ NAV2 C1QTNF1 CDC73 ADAMTSL4 MTUS2 SDCBP	1.05e-07	590	117	13	25910212
Pubmed	Cloning, expression patterns, and chromosome localization of three human and two mouse homologues of GABA(A) receptor-associated protein.	GABARAP GABARAPL1 GABARAPL3	1.48e-07	4	117	3	11414770
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	INCENP PCDHGA11 XPNPEP2 BTBD1 AP3M1 KLHL29 LOXHD1 NAV2 MUC2 DHX34 ADAMTSL4 GOLGA3	3.84e-07	552	117	12	10737800
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	STAM2 HIVEP1 APC UBN2 PIAS2 TTK NFATC3 CLTC CRYBG3 LRIF1 FOXK1 KNL1	7.46e-07	588	117	12	38580884
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	FLNB HCN1 APC CHD9 QRICH1 ACTN1 STAM BTBD1 PIAS2 RXRG OTOF CLTC ENPP5 MTUS2 SDCBP GOLGA3 PINK1	1.47e-06	1285	117	17	35914814
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	FLNB HIVEP1 APC ANKHD1 PIAS2 RAB3GAP2 ANKRD17 CRYBG3 GOLGA3 KNL1	1.61e-06	418	117	10	34709266
Pubmed	Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.	GABARAP IFNGR1 GABARAPL1	2.05e-06	8	117	3	28604719
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	VWA3A HIVEP1 HCN1 STAM ANKHD1 CLOCK IGSF10 RAB3GAP2 NCOA1 ATP1A4 CTSE HYDIN	3.66e-06	686	117	12	29987050
Pubmed	Ubiquitin-specific protease 8 deubiquitinates Sec31A and decreases large COPII carriers and collagen IV secretion.	STAM2 STAM CLTC	6.00e-06	11	117	3	29604273
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	STAM2 HIVEP1 HJURP APC TTK LSR NFATC3 RAB3GAP2 NAV2 ANKRD17 CRYBG3 FOXK1 AHNAK2	6.95e-06	861	117	13	36931259
Pubmed	Adiponectin suppresses tumorigenesis in Apc(Min)(/+) mice.	APC ADIPOQ	1.12e-05	2	117	2	19646806
Pubmed	Induction of natural killer T cell-dependent alloreactivity by administration of granulocyte colony-stimulating factor after bone marrow transplantation.	IFNGR1 CSF3R	1.12e-05	2	117	2	19330008
Pubmed	Estrogen receptor beta deficiency enhances small intestinal tumorigenesis in ApcMin/+ mice.	ESR2 APC	1.12e-05	2	117	2	18464259
Pubmed	Selection of estrogen receptor beta- and thyroid hormone receptor beta-specific coactivator-mimetic peptides using recombinant peptide libraries.	ESR2 NCOA1	1.12e-05	2	117	2	10809226
Pubmed	Loss of adiponectin promotes intestinal carcinogenesis in Min and wild-type mice.	APC ADIPOQ	1.12e-05	2	117	2	21334339
Pubmed	Curcumin inhibits BACE1 expression through the interaction between ERβ and NFκB signaling pathway in SH-SY5Y cells.	ESR2 BACE1	1.12e-05	2	117	2	31595422
Pubmed	Cloning from the thyroid of a protein related to actin binding protein that is recognized by Graves disease immunoglobulins.	FLNB TSHR	1.12e-05	2	117	2	8327473
Pubmed	Ligand-independent recruitment of SRC-1 to estrogen receptor beta through phosphorylation of activation function AF-1.	ESR2 NCOA1	1.12e-05	2	117	2	10230404
Pubmed	Dietary induction of colonic tumors in a mouse model of sporadic colon cancer.	APC MUC2	1.12e-05	2	117	2	18829535
Pubmed	Sumoylation delimits KLF8 transcriptional activity associated with the cell cycle regulation.	KLF8 PIAS2	1.12e-05	2	117	2	16617055
Pubmed	Winnie-APCMin/+ Mice: A Spontaneous Model of Colitis-Associated Colorectal Cancer Combining Genetics and Inflammation.	APC MUC2	1.12e-05	2	117	2	32340123
Pubmed	Interaction of Muc2 and Apc on Wnt signaling and in intestinal tumorigenesis: potential role of chronic inflammation.	APC MUC2	1.12e-05	2	117	2	18794118
Pubmed	TOX and ADIPOQ Gene Polymorphisms Are Associated with Antipsychotic-Induced Weight Gain in Han Chinese.	TOX ADIPOQ	1.12e-05	2	117	2	28327672
Pubmed	PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1.	APC MUC2	1.12e-05	2	117	2	19232344
Pubmed	Expression of gec1/GABARAPL1 versus GABARAP mRNAs in human: predominance of gec1/GABARAPL1 in the central nervous system.	GABARAP GABARAPL1	1.12e-05	2	117	2	14625090
Pubmed	Signal-transducing adaptor molecules STAM1 and STAM2 are required for T-cell development and survival.	STAM2 STAM	1.12e-05	2	117	2	12446783
Pubmed	Structural basis of GABARAP-mediated GABAA receptor trafficking and functions on GABAergic synaptic transmission.	GABRG1 GABARAP	1.12e-05	2	117	2	33436612
Pubmed	Aβ-induced Ca(2+) influx regulates astrocytic BACE1 expression via calcineurin/NFAT4 signals.	BACE1 NFATC3	1.12e-05	2	117	2	22846573
Pubmed	Spindle Assembly Disruption and Cancer Cell Apoptosis with a CLTC-Binding Compound.	APC CLTC	1.12e-05	2	117	2	29769406
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TRPM6 FLNB MARS1 HJURP APC DAG1 ACVR2A ANKHD1 UBN2 AP3M1 VCAN PLCL2 CLTC ANKRD17	1.75e-05	1084	117	14	11544199
Pubmed	Protein profile of exosomes from trabecular meshwork cells.	COL12A1 ACTN1 CLTC SDCBP	2.29e-05	49	117	4	21362503
Pubmed	Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset.	COL12A1 F5 CLTC SDCBP	2.49e-05	50	117	4	24769233
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	FLNB STAM2 ILF3 MARS1 APC STAM TTK AP3M1 RAB3GAP2 ANKRD17 CRYBG3	2.83e-05	708	117	11	39231216
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	FLNB MARS1 APC ANKHD1 CNDP2 CDC73 GOLGA3 AHNAK2	3.12e-05	360	117	8	33111431
Pubmed	Degree and site of chromosomal instability define its oncogenic potential.	APC TTK	3.36e-05	3	117	2	32198375
Pubmed	Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization.	GABARAP GABARAPL1	3.36e-05	3	117	2	28729737
Pubmed	Pharmacogenomic association of nonsynonymous SNPs in SIGLEC12, A1BG, and the selectin region and cardiovascular outcomes.	SIGLEC12 F5	3.36e-05	3	117	2	23690342
Pubmed	Estrogen receptors alpha and beta are inhibitory modifiers of Apc-dependent tumorigenesis in the proximal colon of Min/+ mice.	ESR2 APC	3.36e-05	3	117	2	17332369
Pubmed	Sin3 interacts with Foxk1 and regulates myogenic progenitors.	SIN3A FOXK1	3.36e-05	3	117	2	22476904
Pubmed	Effects of deficiencies of STAMs and Hrs, mammalian class E Vps proteins, on receptor downregulation.	STAM2 STAM	3.36e-05	3	117	2	13679051
Pubmed	Genetic analysis reveals that amyloid precursor protein and death receptor 6 function in the same pathway to control axonal pruning independent of β-secretase.	BACE1 TNFRSF21	3.36e-05	3	117	2	24806670
Pubmed	A death receptor 6-amyloid precursor protein pathway regulates synapse density in the mature CNS but does not contribute to Alzheimer's disease-related pathophysiology in murine models.	BACE1 TNFRSF21	3.36e-05	3	117	2	24806669
Pubmed	A synaptic F-actin network controls otoferlin-dependent exocytosis in auditory inner hair cells.	ACTN1 OTOF	3.36e-05	3	117	2	26568308
Pubmed	Genetic mapping of Mom5, a novel modifier of Apc(Min)-induced intestinal tumorigenesis.	ESR2 APC	3.36e-05	3	117	2	19574546
Pubmed	METTL3 promotes hyperoxia-induced pyroptosis in neonatal bronchopulmonary dysplasia by inhibiting ATG8-mediated autophagy.	GABARAP GABARAPL1	3.36e-05	3	117	2	37478627
Pubmed	PP2A-B56 opposes Mps1 phosphorylation of Knl1 and thereby promotes spindle assembly checkpoint silencing.	TTK KNL1	3.36e-05	3	117	2	25246613
Pubmed	Modes and regulation of endocytic membrane retrieval in mouse auditory hair cells.	OTOF CLTC	3.36e-05	3	117	2	24431429
Pubmed	Hybrid structural model of the complete human ESCRT-0 complex.	STAM2 STAM	3.36e-05	3	117	2	19278655
Pubmed	Deletion of TNF in Winnie-APCMin/+ Mice Reveals Its Dual Role in the Onset and Progression of Colitis-Associated Colorectal Cancer.	APC MUC2	3.36e-05	3	117	2	36499472
Pubmed	MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components.	TTK KNL1	3.36e-05	3	117	2	22660415
Pubmed	Effects of C-terminal modifications of GEC1 protein and gamma-aminobutyric acid type A (GABA(A)) receptor-associated protein (GABARAP), two microtubule-associated proteins, on kappa opioid receptor expression.	GABARAP GABARAPL1	3.36e-05	3	117	2	21388957
Pubmed	GABA(A)-receptor-associated protein links GABA(A) receptors and the cytoskeleton.	GABARAP GABARAPL1	3.36e-05	3	117	2	9892355
Pubmed	Lack of GABARAP-Type Proteins Is Accompanied by Altered Golgi Morphology and Surfaceome Composition.	GABARAP GABARAPL1	3.36e-05	3	117	2	33374830
Pubmed	Arginine68 is an essential residue for the C-terminal cleavage of human Atg8 family proteins.	GABARAP GABARAPL1	3.36e-05	3	117	2	23721406
Pubmed	Association with Hrs is required for the early endosomal localization, stability, and function of STAM.	STAM2 STAM	3.36e-05	3	117	2	15113837
Pubmed	Kaiso-deficient mice show resistance to intestinal cancer.	APC MUC2	3.36e-05	3	117	2	16354691
Pubmed	Starch binding domain-containing protein 1/genethonin 1 is a novel participant in glycogen metabolism.	GABARAP GABARAPL1	3.36e-05	3	117	2	20810658
Pubmed	Apc deficiency is associated with increased Egfr activity in the intestinal enterocytes and adenomas of C57BL/6J-Min/+ mice.	APC CLTC	3.36e-05	3	117	2	15294912
Pubmed	In vitro fluorescence anisotropy analysis of the interaction of full-length SRC1a with estrogen receptors alpha and beta supports an active displacement model for coregulator utilization.	ESR2 NCOA1	3.36e-05	3	117	2	17135255
Pubmed	Phospholipase C-related catalytically inactive protein (PRIP) regulates lipolysis in adipose tissue by modulating the phosphorylation of hormone-sensitive lipase.	LIPE PLCL2	3.36e-05	3	117	2	24945349
Pubmed	Mask family proteins ANKHD1 and ANKRD17 regulate YAP nuclear import and stability.	ANKHD1 ANKRD17	3.36e-05	3	117	2	31661072
Pubmed	Disruption of estrogen receptor signaling enhances intestinal neoplasia in Apc(Min/+) mice.	ESR2 APC	3.36e-05	3	117	2	19520794
Pubmed	Further studies of genetic susceptibility to Graves' disease in a Russian population.	ESR2 TSHR	3.36e-05	3	117	2	11887032
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	HIVEP1 SIN3A UBN2 NCOA1 CDC73 FOXK1 KNL1	3.60e-05	268	117	7	33640491
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	HIVEP1 ACTN1 C1QTNF1 UQCRC2 GOLGA3	5.11e-05	118	117	5	21078624
Pubmed	The Vps27/Hrs/STAM (VHS) Domain of the Signal-transducing Adaptor Molecule (STAM) Directs Associated Molecule with the SH3 Domain of STAM (AMSH) Specificity to Longer Ubiquitin Chains and Dictates the Position of Cleavage.	STAM2 STAM	6.70e-05	4	117	2	26601948
Pubmed	PX-RICS mediates ER-to-Golgi transport of the N-cadherin/beta-catenin complex.	GABARAP GABARAPL1	6.70e-05	4	117	2	18451111
Pubmed	A functional interaction between RHA and Ubc9, an E2-like enzyme specific for Sumo-1.	ILF3 PIAS2	6.70e-05	4	117	2	15312759
Pubmed	Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs.	GABARAP GABARAPL1	6.70e-05	4	117	2	30767700
Pubmed	STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes.	STAM2 STAM	6.70e-05	4	117	2	12551915
Pubmed	Colorectal cancer in mice genetically deficient in the mucin Muc2.	APC MUC2	6.70e-05	4	117	2	11872843
Pubmed	Association of lifestyle factors, polymorphisms in adiponectin, perilipin and hormone sensitive lipase, and clinical markers in Japanese males.	LIPE ADIPOQ	6.70e-05	4	117	2	20495294
Pubmed	Gene fusion and overlapping reading frames in the mammalian genes for 4E-BP3 and MASK.	ANKHD1 ANKRD17	6.70e-05	4	117	2	14557257
Pubmed	Contribution of steroid receptor coactivator-1 and CREB binding protein in ligand-independent activity of estrogen receptor beta.	ESR2 NCOA1	6.70e-05	4	117	2	11358671
Pubmed	Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs.	SIN3A FOXK1	6.70e-05	4	117	2	25402684
Pubmed	STAM proteins bind ubiquitinated proteins on the early endosome via the VHS domain and ubiquitin-interacting motif.	STAM2 STAM	6.70e-05	4	117	2	12972556
Pubmed	Variation in estrogen-related genes and cross-sectional and longitudinal blood pressure in the Framingham Heart Study.	ESR2 NCOA1	6.70e-05	4	117	2	16269961
Pubmed	Estrogen receptor α or β loss in the colon of Min/+ mice promotes crypt expansion and impairs TGFβ and HNF3β signaling.	ESR2 APC	6.70e-05	4	117	2	24104551
Pubmed	Subunit specificity and interaction domain between GABA(A) receptor-associated protein (GABARAP) and GABA(A) receptors.	GABRG1 GABARAP	6.70e-05	4	117	2	11948245
Pubmed	A sequential multi-target Mps1 phosphorylation cascade promotes spindle checkpoint signaling.	TTK KNL1	6.70e-05	4	117	2	28072388
Pubmed	STAM adaptor proteins interact with COPII complexes and function in ER-to-Golgi trafficking.	STAM2 STAM	6.70e-05	4	117	2	19054391
Pubmed	Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.	ESR2 ACTN1 RXRG GABARAPL1 NCOA1	9.02e-05	133	117	5	15604093
Pubmed	Human transcription factor protein interaction networks.	KLF8 HIVEP1 MARS1 SIN3A ANKHD1 UBN2 PIAS2 NFATC3 NCOA1 ANKRD17 ELF1 UQCRC2 LRIF1 FOXK1 RAI2	9.24e-05	1429	117	15	35140242
Pubmed	Conformational changes and coactivator recruitment by novel ligands for estrogen receptor-alpha and estrogen receptor-beta: correlations with biological character and distinct differences among SRC coactivator family members.	ESR2 NCOA1	1.11e-04	5	117	2	11014206
Pubmed	Structure and ubiquitin binding of the ubiquitin-interacting motif.	STAM2 STAM	1.11e-04	5	117	2	12750381
Pubmed	Efficient T-cell receptor signaling requires a high-affinity interaction between the Gads C-SH3 domain and the SLP-76 RxxK motif.	STAM2 STAM	1.11e-04	5	117	2	17235283
Pubmed	Ligands specify coactivator nuclear receptor (NR) box affinity for estrogen receptor subtypes.	ESR2 NCOA1	1.11e-04	5	117	2	11376110
Pubmed	Beta-catenin induces beta-TrCP-mediated PER2 degradation altering circadian clock gene expression in intestinal mucosa of ApcMin/+ mice.	APC CLOCK	1.11e-04	5	117	2	19106159
Pubmed	PTP1B targets the endosomal sorting machinery: dephosphorylation of regulatory sites on the endosomal sorting complex required for transport component STAM2.	STAM2 STAM	1.11e-04	5	117	2	20504764
Pubmed	Clathrin anchors deubiquitinating enzymes, AMSH and AMSH-like protein, on early endosomes.	STAM CLTC	1.11e-04	5	117	2	16716190
Pubmed	Differential recruitment of coregulator proteins steroid receptor coactivator-1 and silencing mediator for retinoid and thyroid receptors to the estrogen receptor-estrogen response element by beta-estradiol and 4-hydroxytamoxifen in human breast cancer.	ESR2 NCOA1	1.11e-04	5	117	2	14715875
Pubmed	Novel roles for the E3 ubiquitin ligase atrophin-interacting protein 4 and signal transduction adaptor molecule 1 in G protein-coupled receptor signaling.	STAM2 STAM	1.11e-04	5	117	2	22275353
Pubmed	Regulation of epidermal growth factor receptor ubiquitination and trafficking by the USP8·STAM complex.	STAM2 STAM	1.11e-04	5	117	2	20736164
Pubmed	Tyrosine phosphorylation mapping of the epidermal growth factor receptor signaling pathway.	STAM2 STAM	1.11e-04	5	117	2	11687594
Pubmed	Isoform-selective interactions between estrogen receptors and steroid receptor coactivators promoted by estradiol and ErbB-2 signaling in living cells.	ESR2 NCOA1	1.11e-04	5	117	2	12554772
Pubmed	The nuclear receptor coactivator PGC-1alpha exhibits modes of interaction with the estrogen receptor distinct from those of SRC-1.	ESR2 PGC	1.11e-04	5	117	2	15784253
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	FLNB COL12A1 INCENP MARS1 APC GABARAP LAMC3 STAM ANKHD1 TTK AP3M1 CLTC UQCRC2 SDCBP	1.20e-04	1297	117	14	33545068
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	FLNB HIVEP1 EFS SIN3A ACTN1 ADAMTSL4 MTUS2 GOLGA3 RAI2	1.21e-04	560	117	9	21653829
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	FLNB KCNH7 HCN1 PCLO APC DAG1 CNKSR2 AP3M1 RAB3GAP2 CLTC CNDP2 UQCRC2 CRYBG3	1.24e-04	1139	117	13	36417873
GeneFamily	ESCRT-0	STAM2 STAM	6.38e-05	3	84	2	1115
GeneFamily	PDZ domain containing	PCLO CNKSR2 TAX1BP3 SDCBP AHNAK2	7.12e-04	152	84	5	1220
Coexpression	GSE2405_0H_VS_3H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN	EFS DAG1 CELSR1 CSF3R ENPP5 C1QTNF1 ADAMTSL4 GPR148	2.91e-06	198	116	8	M6213
Coexpression	GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN	TOX CHD9 UBN2 HEG1 GABARAPL1 CLTC ENPP5 CDC73	3.14e-06	200	116	8	M6513
Coexpression	GSE4142_NAIVE_BCELL_VS_PLASMA_CELL_DN	VPS11 HJURP LSR CELSR1 ADAMTSL4 LRIF1 GOLGA3	3.13e-05	200	116	7	M6374
Coexpression	GSE33162_HDAC3_KO_VS_HDAC3_KO_4H_LPS_STIM_MACROPHAGE_UP	VPS11 INPP5D QRICH1 SIN3A CLTC CNDP2 ANKRD17	3.13e-05	200	116	7	M9041
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-1\|TCGA-Adrenal / Sample_Type by Project: Shred V9	EFS NEXMIF HCN1 PCLO BTBD10 CNKSR2 RXRG	4.54e-07	179	116	7	431e1b29015ec817f778499106d24b19cfc825ae
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	INCENP HJURP DCLRE1B OTOF CTSW KNL1	4.25e-06	162	116	6	af9999e5fcd28ff1f401d52fd220315752c40027
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 GABRG1 KCNH7 PIAS2 GABARAPL1 NAV2	8.54e-06	183	116	6	2f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 PCLO CNKSR2 LOXHD1 ATP1A4 HYDIN	8.81e-06	184	116	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TRPM6 KCNH7 MUC19 NCF2 F5 CSF3R	8.81e-06	184	116	6	7ecdf2645e9378cf2f5ce4557f2cf100e6f184ba
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 PCLO CNKSR2 LOXHD1 ATP1A4 HYDIN	8.81e-06	184	116	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 PCLO CNKSR2 LOXHD1 ATP1A4 HYDIN	8.81e-06	184	116	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	3'_v3-GI_small-bowel-Myeloid_Mac-Cycling_Myeloid-Mac\|GI_small-bowel / Manually curated celltypes from each tissue	SIGLEC12 HJURP BACE1 ACTN1 TTK KNL1	1.09e-05	191	116	6	c3944332c5226b0113f8aa9ac07837b755606c6c
ToppCell	10x5'v1-week_17-19-Myeloid_neutrophil-granulo-neutrophil-neutrophil\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	NCF2 F5 GABARAPL1 CSF3R VCAN SDCBP	1.19e-05	194	116	6	e2d0dfb92356fa7ad7008aa8ac4198e2ac5d2495
ToppCell	COVID_vent-Myeloid-Monocytic-Neutrophil\|COVID_vent / Disease condition, Lineage, Cell class and subclass	TRPM6 KCNH7 NCF2 ACTN1 CSF3R SDCBP	1.19e-05	194	116	6	eb23b171e429165dd26a64377eae7fa2ce25f547
ToppCell	facs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB ACTN1 KLHL29 IGSF10 ADAMTSL4 SDCBP	1.26e-05	196	116	6	90edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCell	10x5'v1-week_17-19-Myeloid_neutrophil-granulo-neutrophil\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	NCF2 F5 GABARAPL1 CSF3R VCAN SDCBP	1.26e-05	196	116	6	ad193b231ff2f7c72590fab79919c179d5d2f327
ToppCell	facs-Skin-Telogen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB ACTN1 KLHL29 IGSF10 ADAMTSL4 SDCBP	1.26e-05	196	116	6	c936014125b2ed5f796221b74acb77b8f8359875
ToppCell	URO-Myeloid-CD14_Mono\|URO / Disease, Lineage and Cell Type	GABARAP NCF2 CSF3R VCAN CLTC SDCBP	1.30e-05	197	116	6	45c16125fa32e50304fdd45a7cb457488bd50ee3
ToppCell	IIH-granulo1-\|IIH / Condition, Cell_class and T cell subcluster	GABARAP NCF2 IFNGR1 CSF3R VCAN SDCBP	1.30e-05	197	116	6	51be6d5652b17c70f3a33f244efc3b728ec56f5b
ToppCell	systemic_lupus_erythematosus-flare-Myeloid-classical_monocyte-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GABARAP NCF2 IFNGR1 CSF3R VCAN SDCBP	1.30e-05	197	116	6	ffaf2d7b6aa82008bd64a691b48113626343872c
ToppCell	systemic_lupus_erythematosus-flare-Myeloid-classical_monocyte\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GABARAP NCF2 IFNGR1 CSF3R VCAN SDCBP	1.30e-05	197	116	6	94e2cc7ec531e58b8ed7e5601fdf8c4bbc3582c8
ToppCell	IIH-granulo1\|IIH / Condition, Cell_class and T cell subcluster	GABARAP NCF2 IFNGR1 CSF3R VCAN SDCBP	1.30e-05	197	116	6	39637e8b726bc58c0a6885c49713111f97aff881
ToppCell	TCGA-Skin-Metastatic-Melanoma\|TCGA-Skin / Sample_Type by Project: Shred V9	INPP5D HEG1 NFATC3 RAB3GAP2 PLCL2 CDC73	1.34e-05	198	116	6	af4fb9eb2295c7b90624b38ba25619aa15254efa
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	INCENP HJURP ACTN1 IGSF10 VCAN KNL1	1.34e-05	198	116	6	148f5fee19ea8dff7f2de4ca69c3b03e5221985d
ToppCell	systemic_lupus_erythematosus-treated-Myeloid-classical_monocyte-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GABARAP NCF2 IFNGR1 CSF3R VCAN SDCBP	1.34e-05	198	116	6	c79c1738560d78b63dbed5f2f9621dbc1c2363cb
ToppCell	systemic_lupus_erythematosus-treated-Myeloid-classical_monocyte\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GABARAP NCF2 IFNGR1 CSF3R VCAN SDCBP	1.34e-05	198	116	6	1d1c80569f1e307285ba0ebaf5c72e0b5b538864
ToppCell	systemic_lupus_erythematosus-treated-Myeloid\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GABARAP NCF2 IFNGR1 CSF3R VCAN SDCBP	1.34e-05	198	116	6	f37578f156e8aed2ce30cfa837ae04dd18de05d0
ToppCell	systemic_lupus_erythematosus-flare-Myeloid\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	GABARAP NCF2 IFNGR1 CSF3R VCAN SDCBP	1.34e-05	198	116	6	189346c5eb715f3be427bec3b8e067ababb5b475
ToppCell	TCGA-Skin-Metastatic\|TCGA-Skin / Sample_Type by Project: Shred V9	INPP5D HEG1 NFATC3 RAB3GAP2 PLCL2 CDC73	1.34e-05	198	116	6	ad39cce004867f083f8da1954e0cf5a263815184
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma\|TCGA-Skin / Sample_Type by Project: Shred V9	INPP5D HEG1 NFATC3 RAB3GAP2 PLCL2 CDC73	1.34e-05	198	116	6	62cbf4b29e8af4983fb47a17f96da62682a5137e
ToppCell	COVID-19_Mild-Classical_Monocyte\|COVID-19_Mild / Disease condition and Cell class	NCF2 ACTN1 F5 CSF3R VCAN SDCBP	1.34e-05	198	116	6	30ada3de865b6fb2b14196a1cbfd4740c6a57ce3
ToppCell	10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-neutrophil-neutrophil\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NCF2 F5 IFNGR1 CSF3R VCAN SDCBP	1.38e-05	199	116	6	0dde17381b8a95bfddb4d1052b13d33f37b05d13
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FLNB ILF3 GABARAP NCF2 VCAN CNDP2	1.38e-05	199	116	6	379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCell	COVID_vent-Myeloid\|COVID_vent / Disease condition, Lineage, Cell class and subclass	NCF2 F5 IFNGR1 CSF3R VCAN SDCBP	1.41e-05	200	116	6	621af09aae34226902c03edf556562f3ab35a7d8
ToppCell	Sepsis-URO-Myeloid-CD14+_Monocyte\|URO / Disease, condition lineage and cell class	GABARAP NCF2 CSF3R VCAN CLTC SDCBP	1.41e-05	200	116	6	209976dbbfc1edbeb3ea128cd0453ec9572f54cb
ToppCell	COVID_vent-Myeloid-Monocytic-CD14+_Monocyte\|COVID_vent / Disease condition, Lineage, Cell class and subclass	NCF2 F5 IFNGR1 CSF3R VCAN SDCBP	1.41e-05	200	116	6	e57452b73abb21cb3f645d45523ab93f6bef0243
ToppCell	COVID_vent-Myeloid-Monocytic\|COVID_vent / Disease condition, Lineage, Cell class and subclass	NCF2 F5 IFNGR1 CSF3R VCAN SDCBP	1.41e-05	200	116	6	b0a5bee87700ce38f26f95a6f491da7e27cade51
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FLNB GABARAP NCF2 VCAN CNDP2 SDCBP	1.41e-05	200	116	6	851c57187db8bc91a393655bca5f13e787a723d4
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MTIF3 DCLRE1B F5 RAB3GAP2 NAV2	2.58e-05	133	116	5	f6e9a1301a3379847b215303a9b0c028841e2cc0
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MTIF3 DCLRE1B F5 RAB3GAP2 NAV2	2.58e-05	133	116	5	292ecfcadbaf15e0d34a3ab9bf511ab1065888bd
ToppCell	BLOOD--(3)_MNP-(3)_Classical_Mono-1\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	GABARAP F5 CSF3R VCAN SDCBP	3.53e-05	142	116	5	395f80e99be4a0ef07fb9d65c74399e7e67c9a8d
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_D2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	COL12A1 PPIP5K1 ATP1A4 CTSW AHNAK2	4.59e-05	150	116	5	ecc4fc94958cf2378dd003966dccba81b3c00f8e
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-Like-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWA3A INCENP HCN1 HJURP LAMC3	4.74e-05	151	116	5	c06a54afe918b14f885d6a85fbcf81e80f33afae
ToppCell	367C-Lymphocytic-ILC-ILC-3\|367C / Donor, Lineage, Cell class and subclass (all cells)	ANKHD1 LIPE GABARAPL1 PPIP5K1 CTSW	5.04e-05	153	116	5	9d64aadbb4bb28469af1d728457b431e21577429
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA3A ATP6V1B1 EFS INPP5D FAM135B	5.04e-05	153	116	5	3b1b0cc8e9dd2b1484649789330713282ee44414
ToppCell	facs-Skin-Telogen-3m-Epithelial-inner_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACTN1 KLHL29 IGSF10 BPIFB2 SDCBP	5.53e-05	156	116	5	ba9dfee9373d657d2a55572b41fc62001ad8b037
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM6 HJURP SIN3A F5 CRYBG3	5.70e-05	157	116	5	a426c54fd1545093d41426e9620862f71bd06f6b
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA3A COL12A1 HCN1 MUC19 HYDIN	6.23e-05	160	116	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWA3A COL12A1 HCN1 MUC19 HYDIN	6.23e-05	160	116	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	Frontal_cortex\|World / BrainAtlas - Mouse McCarroll V32	COL12A1 KCNH7 HIVEP1 TOX CNKSR2	7.01e-05	164	116	5	e09291711abf8680e78170328313719092b0142f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	INCENP HJURP DCLRE1B TTK KNL1	7.21e-05	165	116	5	eec2d327c94832d1390314c93ef6a2be4648478b
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HJURP SIN3A TTK CTSW KNL1	7.42e-05	166	116	5	21ba5fd755c0fb31ada42a1b5d60bede0153323d
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMC3 ADH7 IGSF10 TMEM174 ATP1A4	7.85e-05	168	116	5	d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCell	facs-Lung-nan-3m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF2 F5 TNFRSF21 CSF3R VCAN	8.07e-05	169	116	5	05b138511039f1255a5f647040b1b9bdf222bd52
ToppCell	facs-Lung-nan-3m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF2 F5 TNFRSF21 CSF3R VCAN	8.07e-05	169	116	5	bf0a97f53d6e3f9ffeaeae0402b010c49a6cccb7
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HJURP LAMC3 TSHR VCAN KNL1	8.30e-05	170	116	5	a7184dc41f90caa753860ed0f65a18133f84bc5f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 HJURP LAMC3 VCAN KNL1	8.53e-05	171	116	5	b0373ed8283ee1792b6a490bff93906546978593
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 HJURP LAMC3 VCAN KNL1	8.53e-05	171	116	5	b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	INCENP HJURP TTK LSR KNL1	8.53e-05	171	116	5	621f9da0bfa09c86fc89fd26919403e94cd56d2b
ToppCell	droplet-Lung-21m-Hematologic-myeloid-classical_monocyte\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NCF2 F5 TNFRSF21 CSF3R VCAN	8.77e-05	172	116	5	a53c906539557594ef10368bc29aec4af063fd37
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INCENP HJURP TTK CTSW KNL1	8.77e-05	172	116	5	e495efd25aec60b97ac2b5aa861651bd73174a17
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SIGLEC12 INPP5D NCF2 CSF3R VCAN	9.01e-05	173	116	5	0a0127bcb1d7b2b6125faef576dd843055095528
ToppCell	control-Lymphocytic-CD4_T_cells_3\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	TOX TSHR STAM F5 RXRG	9.01e-05	173	116	5	0c9fb18536ddd61b51b7bb4d40841f67b017f360
ToppCell	droplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NCF2 F5 TNFRSF21 CSF3R VCAN	9.01e-05	173	116	5	9acad7ec70f713fe3db6cef7bbe3b183bf16ae67
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	INCENP HJURP LAMC3 TTK NAV2	9.26e-05	174	116	5	72df66319f6efbd88ecf439013d97409fbf3cb52
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	INCENP HJURP LAMC3 TTK NAV2	9.26e-05	174	116	5	c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	INCENP HJURP TTK RXRG KNL1	9.26e-05	174	116	5	dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell	droplet-Lung-21m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	INCENP HJURP SIN3A TTK KNL1	9.51e-05	175	116	5	6751ee4b312d7f87275f2c35e5878cfc3be3ebe3
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL12A1 INCENP HJURP IGSF10 KNL1	9.51e-05	175	116	5	a154b28b0b2180652d51d4c7d804b3b81b35899e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KCNH7 INCENP HJURP TTK KNL1	9.51e-05	175	116	5	876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell	COPD-Lymphoid-ILC_A\|COPD / Disease state, Lineage and Cell class	TOX INPP5D STAM PLCL2 CTSW	9.77e-05	176	116	5	484452cb38fe4604f0910a068361ed461b5b0c21
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD9 CLOCK IGSF10 HEG1 GOLGA3	9.77e-05	176	116	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	Control-Lymphoid-ILC_B\|World / Disease state, Lineage and Cell class	TOX INPP5D STAM PLCL2 CTSW	9.77e-05	176	116	5	57ad9c9f5fda6bc24695587ed14190514fd8d96a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ESR2 KLHL29 CELSR1 HYDIN MTUS2	1.00e-04	177	116	5	da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCell	Control-Lymphoid-ILC_B\|Control / Disease state, Lineage and Cell class	TOX INPP5D STAM PLCL2 CTSW	1.00e-04	177	116	5	3d0f4b4054185ba77071efbe53df34fee84b9b24
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TOX NEXMIF MUC19 STAM PLCL2	1.06e-04	179	116	5	d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCell	IPF-Lymphoid-ILC_A\|World / Disease state, Lineage and Cell class	TOX INPP5D STAM PLCL2 CTSW	1.14e-04	182	116	5	f91bb45baaec76cb3bb26eedbcf0709b2492e93f
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHGA11 LSR CELSR1 GABARAPL1 RAI2	1.17e-04	183	116	5	6c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCell	IPF-Lymphoid-ILC_A\|IPF / Disease state, Lineage and Cell class	TOX INPP5D STAM PLCL2 CTSW	1.17e-04	183	116	5	49bfeaae13eb236f61a5486ee75c39789936bb8a
ToppCell	AT1-AT2_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	FLNB COL12A1 PCLO HEG1 RAI2	1.17e-04	183	116	5	6821dca076318115d360ff426eb1218cfe104063
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic\|bone_marrow / Manually curated celltypes from each tissue	FLNB INCENP HJURP TTK KNL1	1.23e-04	185	116	5	9d3168c7f0b1d739f78b368969cf5c77ce202b97
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	INCENP HJURP TTK RXRG KNL1	1.23e-04	185	116	5	6aeae77a087d695b1e58c5f63265e7113aa2e343
ToppCell	COVID-19_Convalescent-PLT_4\|World / Disease Group and Platelet Clusters	GABARAP CHD9 IFNGR1 ELF1 CDC73	1.27e-04	186	116	5	5954a1e3ffafb33f2a9bc87af3343f304fda4c92
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NCF2 F5 CSF3R VCAN SDCBP	1.27e-04	186	116	5	05c40bac5c0ade8b67b7c2112739466e02dbf22b
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HCN1 PCLO MUC19 CSF3R VCAN	1.27e-04	186	116	5	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	Control-Lymphoid-ILC_A\|World / Disease state, Lineage and Cell class	TOX INPP5D STAM PLCL2 CTSW	1.27e-04	186	116	5	7bc939bf4e71bb4c6409b862c1f6c547d775e089
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	INCENP HJURP ACTN1 TTK KNL1	1.30e-04	187	116	5	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	COL12A1 CHD9 VCAN NAV2 ADAMTSL4	1.30e-04	187	116	5	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	INCENP HJURP ACTN1 TTK KNL1	1.30e-04	187	116	5	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	facs-Heart-LA-24m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LSR CELSR1 HEG1 GABARAPL1 RAI2	1.30e-04	187	116	5	d9943e65eedab73d141eae524e2411653a751705
ToppCell	facs-Heart-LA-24m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LSR CELSR1 HEG1 GABARAPL1 RAI2	1.30e-04	187	116	5	7b13c3b67d66f3afb410141d5471c9e78a4d8623
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Striatum / BrainAtlas - Mouse McCarroll V32	CNKSR2 RXRG FAM135B GABARAPL1 OTOF	1.33e-04	188	116	5	e34ea7014c5a059a7db38f78bd903cf02616ddd3
ToppCell	3'_v3-GI_small-bowel-Myeloid_Monocytic-Classical_monocytes\|GI_small-bowel / Manually curated celltypes from each tissue	NCF2 ACTN1 F5 CSF3R VCAN	1.36e-04	189	116	5	74a5e61cd820f2495dde40e766c771a31d8c4e7d
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	INCENP HJURP TTK NAV2 KNL1	1.36e-04	189	116	5	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	COVID-19-Heart-CM_4\|Heart / Disease (COVID-19 only), tissue and cell type	TOX F5 GABARAPL1 PLCL2 C1QTNF1	1.40e-04	190	116	5	3729648a17093b438398b82e32bbccc3af7b8c5d
ToppCell	Smart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MUC19 NCF2 ACTN1 LOXHD1 CSF3R	1.43e-04	191	116	5	d4f77c73311d1149466bbfe4adbd6a301946ec90
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NCF2 F5 LOXHD1 GABARAPL1 VCAN	1.43e-04	191	116	5	63d4226a8b59f648bdc9f41e4b2d750dfa342034
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNB HEG1 VCAN C1QTNF1 ADAMTSL4	1.47e-04	192	116	5	30cefa0990ba1f379f350bfbf994a78db145075e
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	INCENP HJURP TTK NAV2 KNL1	1.47e-04	192	116	5	27723f4e320e49d4a3daafa2d8d3946ff79fab64
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	INCENP HJURP TTK NAV2 KNL1	1.47e-04	192	116	5	0a54c79dcfdeb99e3b512d42b22359618cfd17e9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 LAMC3 CNKSR2 VCAN NAV2	1.47e-04	192	116	5	5105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell	E15.5-Epithelial-alveolar_epithelial_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NEXMIF DAG1 LSR NAV2 ENPP5	1.47e-04	192	116	5	567f4355a01aae1f2eafc16fe86d1538a62030ab
ToppCell	Children_(3_yrs)-Immune-monocyte-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	INPP5D IFNGR1 CSF3R VCAN PLCL2	1.50e-04	193	116	5	58e1930a1d80ad3729ab9604ac8ebf7308232a3d
ToppCell	Leuk-UTI-Myeloid-CD14_Mono\|Leuk-UTI / Disease, Lineage and Cell Type	GABARAP CSF3R VCAN CLTC SDCBP	1.50e-04	193	116	5	d1eac8627d00629ed2e81d3b86778007304efcb7
Disease	neuroticism measurement	KLF8 KCNH7 HIVEP1 HCN1 INPP5D PCLO DAG1 CNKSR2 QRICH1 ACVR2A KLHL29 CSF3R PLCL2	4.22e-05	909	112	13	EFO_0007660
Disease	neurotic disorder	HIVEP1 PCLO ACVR2A FAM135B PLCL2	4.27e-05	101	112	5	EFO_0004257
Disease	t-tau measurement	ILF3 ACVR2A F5 CSF3R AHNAK2	1.22e-04	126	112	5	EFO_0004760
Disease	feeling "fed-up" measurement	HCN1 DAG1 KLHL29 PLCL2	2.04e-04	76	112	4	EFO_0009588
Disease	Pleocytosis	APC CSF3R	2.12e-04	6	112	2	C0151857
Disease	Leukocytosis	APC CSF3R	2.12e-04	6	112	2	C0023518
Disease	bipolar disorder (implicated_via_orthology)	CLOCK TTK	2.96e-04	7	112	2	DOID:3312 (implicated_via_orthology)
Disease	Cerebral ventriculomegaly	SIN3A HYDIN	2.96e-04	7	112	2	C1531647
Disease	Hydrocephalus Ex-Vacuo	SIN3A HYDIN	2.96e-04	7	112	2	C0270720
Disease	Communicating Hydrocephalus	SIN3A HYDIN	2.96e-04	7	112	2	C0009451
Disease	Rectal Neoplasms	APC MUC2	2.96e-04	7	112	2	C0034885
Disease	Fetal Cerebral Ventriculomegaly	SIN3A HYDIN	2.96e-04	7	112	2	C2936718
Disease	Rectal Carcinoma	APC MUC2	2.96e-04	7	112	2	C0007113
Disease	Post-Traumatic Hydrocephalus	SIN3A HYDIN	2.96e-04	7	112	2	C0477432
Disease	Obstructive Hydrocephalus	SIN3A HYDIN	2.96e-04	7	112	2	C0549423
Disease	Adenoma, Microcystic	APC TSHR MUC2	3.47e-04	36	112	3	C0205648
Disease	Adenoma, Monomorphic	APC TSHR MUC2	3.47e-04	36	112	3	C0205649
Disease	Adenoma, Basal Cell	APC TSHR MUC2	3.47e-04	36	112	3	C0205646
Disease	Follicular adenoma	APC TSHR MUC2	3.47e-04	36	112	3	C0205647
Disease	Papillary adenoma	APC TSHR MUC2	3.47e-04	36	112	3	C0205650
Disease	Adenoma, Trabecular	APC TSHR MUC2	3.47e-04	36	112	3	C0205651
Disease	Adenoma	APC TSHR MUC2	3.47e-04	36	112	3	C0001430
Disease	Congenital Hydrocephalus	SIN3A HYDIN	3.94e-04	8	112	2	C0020256
Disease	Aqueductal Stenosis	SIN3A HYDIN	3.94e-04	8	112	2	C2936786
Disease	Hydrocephalus	SIN3A HYDIN	5.05e-04	9	112	2	C0020255
Disease	colitis (biomarker_via_orthology)	ESR2 ADIPOQ MUC2	5.49e-04	42	112	3	DOID:0060180 (biomarker_via_orthology)
Disease	pneumonia	ACVR2A F5 MUC2	7.64e-04	47	112	3	EFO_0003106
Disease	colon cancer (implicated_via_orthology)	ESR2 APC	7.68e-04	11	112	2	DOID:219 (implicated_via_orthology)
Disease	alcohol consumption measurement	GABRG1 COL12A1 KCNH7 PCLO LAMC3 QRICH1 ACTN1 FAM135B ADH7 KLHL29 CACNG7 C1QTNF1 BPIFB2	8.73e-04	1242	112	13	EFO_0007878
Disease	Intestinal Neoplasms	APC MUC2	9.19e-04	12	112	2	C0021841
Disease	Intestinal Cancer	APC MUC2	9.19e-04	12	112	2	C0346627
Disease	juvenile polyposis syndrome (implicated_via_orthology)	HIVEP1 ACVR2A	1.08e-03	13	112	2	DOID:0050787 (implicated_via_orthology)
Disease	depressive symptom measurement	HIVEP1 ESR2 PCLO DAG1 CNKSR2 KLHL29 PLCL2	1.23e-03	426	112	7	EFO_0007006
Disease	polycystic kidney disease (implicated_via_orthology)	STAM2 STAM	1.26e-03	14	112	2	DOID:0080322 (implicated_via_orthology)
Disease	Colorectal Carcinoma	NPBWR2 EFS ESR2 APC CNKSR2 STAM F5 BPIFB2 UQCRC2	1.45e-03	702	112	9	C0009402
Disease	neuroticism measurement, cognitive function measurement	HIVEP1 HCN1 PCLO APC ACVR2A KLHL29 PLCL2 NAV2	1.45e-03	566	112	8	EFO_0007660, EFO_0008354
Disease	cancer biomarker measurement	FAM135B PPIP5K1	1.45e-03	15	112	2	EFO_0005127
Disease	Alzheimer's disease (is_implicated_in)	ESR2 BACE1 NCF2 CLOCK	1.64e-03	132	112	4	DOID:10652 (is_implicated_in)
Disease	pro-hydroxy-pro measurement	TRPM6 XPNPEP2	1.65e-03	16	112	2	EFO_0021132
Disease	Polyposis, Adenomatous Intestinal	APC F5	1.65e-03	16	112	2	C2713442
Disease	Familial Intestinal Polyposis	APC F5	1.65e-03	16	112	2	C2713443
Disease	household income, smoking status measurement, educational attainment, protein intake measurement, carbohydrate intake measurement, alcohol consumption measurement, body mass index, energy intake measurement	MTIF3 RAB3GAP2	1.65e-03	16	112	2	EFO_0004340, EFO_0006527, EFO_0007878, EFO_0009374, EFO_0009695, EFO_0010810, EFO_0010811, EFO_0011015
Disease	unipolar depression, mood disorder	DAG1 ACVR2A KLHL29 PLCL2	1.73e-03	134	112	4	EFO_0003761, EFO_0004247
Disease	Adenomatous Polyposis Coli	APC F5	1.87e-03	17	112	2	C0032580
Disease	cardiomyopathy (is_implicated_in)	TSHR ADIPOQ	2.34e-03	19	112	2	DOID:0050700 (is_implicated_in)
Disease	basophil count	GANC MARS1 ACVR2A KLHL29 CSF3R PLCL2 ELF1	2.50e-03	483	112	7	EFO_0005090
Disease	endometriosis	COL12A1 LAMC3 CNKSR2 F5 CDC73	2.79e-03	252	112	5	EFO_0001065
Disease	anxiety disorder (implicated_via_orthology)	HCN1 ESR2	3.14e-03	22	112	2	DOID:2030 (implicated_via_orthology)
Disease	Endometrioma	ESR2 IFNGR1 VCAN NCOA1	3.36e-03	161	112	4	C0269102
Disease	Endometriosis	ESR2 IFNGR1 VCAN NCOA1	3.36e-03	161	112	4	C0014175
Disease	cortical thickness	FLNB COL12A1 LAMC3 BTBD1 CLOCK AP3M1 KLHL29 CELSR1 VCAN NAV2 C1QTNF1	3.41e-03	1113	112	11	EFO_0004840
Disease	primary open angle glaucoma (is_implicated_in)	ESR2 ADIPOQ	3.43e-03	23	112	2	DOID:1070 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
MNYGTSVVVGVPPSA	ADH7	296	P40394
YVEMTVGSPPQTLNI	BACE1	76	P56817
PPQMGEEYSQIIYST	BTBD10	326	Q9BSF8
EQQPQPYVMVVSSSN	ELF1	586	P32519
MAGTNPYTTITPQEI	ACTN1	586	P12814
SAEGPTTQPVDVYMI	ADAMTSL4	571	Q6UY14
VPPITSTEGQVYATM	VCAN	906	P13611
QMQPGGTAISVTVPY	CDC73	411	Q6P1J9
GISKNSYVMPNEPTT	CRYBG3	2191	Q68DQ2
SYVMPNEPTTSNLQV	CRYBG3	2196	Q68DQ2
TSTPIYQMSSLPVNV	ADGRG4	1506	Q8IZF6
SVGLETYVTIPNMPI	ADIPOQ	116	Q15848
YFPEMEVTQPTSNPV	ACVR2A	116	P27037
PPNTQSMVLLEESYV	CDPF1	31	Q6NVV7
NTPMVSTLVYSEGAP	CELSR1	2371	Q9NYQ6
MNLTPTQGSYTFDPV	AP3M1	321	Q9Y2T2
GIVNMDSPYGSVTPS	ANKRD17	2321	O75179
VPLIPDSVQQYMSSS	DCLRE1B	316	Q9H816
DTPVVQMATLTYETP	HJURP	46	Q8NCD3
LHPETTVNMTYQPTT	MTUS2	536	Q5JR59
TYVMTTQGPVQLPVV	RAI2	111	Q9Y5P3
YMPPSTVLQQIDSVA	UQCRC2	406	P22695
DMPITVSYAISGQPV	QRICH1	251	Q2TAL8
PMFTQSVYRVSVPEN	PCDHGA11	241	Q9Y5H2
VSSVFYTTIVPMLNP	OR8G2P	286	Q6IF36
SGYNITIVAMDTGPP	PCDHB1	416	Q9Y5F3
NSPPAMSQYITVGSN	RAB3GAP2	296	Q9H2M9
PQSPEGDTLMGITYT	OR10H5	266	Q8NGA6
TLVTPTLNPMVYSFQ	OR13G1	276	Q8NGZ3
PAVMNYSIPSNVTNL	ESR2	51	Q92731
VEASQMPTVIYVSPV	LRIF1	221	Q5T3J3
MPTVIYVSPVNTVKN	LRIF1	226	Q5T3J3
TVVMKTQPGLPYSQV	NCF2	361	P19878
TQPGLPYSQVRDMVS	NCF2	366	P19878
VQSPACTSYQMTPQG	INCENP	796	Q9NQS7
QKQTTVVPPAYSMVT	KCNH7	1061	Q9NS40
NIPMTVEENGYTPAI	KIAA1109	421	Q2LD37
TVTGPMADYVQEGPI	LOXHD1	1406	Q8IVV2
MEYFGTISIGSPPQN	CTSE	76	P14091
VPETTPLNQDTMGEY	DAG1	836	Q14118
VTYTPSQEGPYMVSV	FLNB	1481	O75369
TSTEPAEYQLMTGLQ	MTIF3	121	Q9H2K0
PYQTQPTFQAVATMS	PCLO	3921	Q9Y6V0
YEATMPTLPQNLEVT	PINK1	171	Q9BXM7
LYVSMPPNQFTDTVG	MUC19	936	Q7Z5P9
TMYPDVPIGQLGQTV	MUC2	1826	Q02817
SAMPRVVPYTQSTIL	ENPP5	401	Q9UJA9
TEPAVEYTLTQMGPV	GANC	296	Q8TET4
VVQSLPMVYTTLPAD	KLF8	181	O95600
AMTPESIYSNPSIQG	KNL1	436	Q8NG31
NNVIPPTSATMGQLY	GABARAP	81	O95166
YTPTINMPNTSVVLD	HEG1	636	Q9ULI3
TPYMVNGQEIPADTL	GOLGA3	341	Q08378
TDLPQTPLVISMSYV	NPBWR2	286	P48146
ITLTSVDPQLQTPMY	OR8J2	46	Q8NGG1
PTSVMQPIYEEATLN	CHD9	1811	Q3L8U1
IAPINYPQMTTLNST	HCN1	636	O60741
SPMTNINYGTEFSPV	IGSF10	831	Q6WRI0
TVSLMQGTIPPEAEY	HYDIN	2981	Q4G0P3
TSMYPATAVPQINIT	C1QTNF1	81	Q9BXJ1
PVVSLNIYDVGPTTM	COL12A1	1476	Q99715
VNSIGPVDPINMEYT	GABRG1	96	Q8N1C3
NNTIPPTSATMGQLY	GABARAPL1	81	Q9H0R8
VQIGPETVMTTLYTA	BTBD1	141	Q9H0C5
EQGASYILPPSMGTQ	GPR148	196	Q8TDV2
TVQIPPSTTYAITPM	ILF3	356	Q12906
NNTIPPTSATMGQLY	GABARAPL3	81	Q9BY60
TYGPITVTINMKPLQ	CTSW	256	P56202
AYMPASIVTSQQPAG	FOXK1	496	P85037
ISSDVSIQMTQNYPP	CACNG7	246	P62955
ALGYPSSPAIQEMVQ	EFS	526	O43281
EIIVTPLYQDTMGPS	CSF3R	501	Q99062
YPNFDVPVTSPTIMN	FAM135B	426	Q49AJ0
EVQNMYVGPQTIPAT	DHX34	1006	Q14147
PSSINYMVAPVTGND	SDCBP	86	O00560
TPTNVTIESYNMNPI	IFNGR1	31	P15260
SQGATQMPLYSSPIV	LIPE	951	Q05469
CTYQMTSTPTQPIVI	LSR	111	Q86X29
PSAGRPMDYQVSITV	OTOF	246	Q9HC10
TQSSPTKGVLMYQPS	PIAS2	496	O75928
SRIYPEEMIQTGISP	ATP6V1B1	156	P15313
VPSSTYVPKGMNSTE	TNFRSF21	241	O75509
MSTINGYVPESITTL	F5	586	P12259
PAQPGVYNNMSITVS	NCOA1	1306	Q15788
VVSMENNLTPTTYNP	NEXMIF	921	Q5QGS0
SEQYPTMELQGIVPE	PLCL2	981	Q9UPR0
PYIIGTMNQATSSTP	NAV2	2251	Q8IVL1
SITEIINPNYMGVGP	INPP5D	906	Q92835
ETMQSATGIQYSVTP	SIN3A	46	Q96ST3
ISYPPQNLTMTVFQG	SIGLEC12	361	Q96PQ1
PVGPESQIRYSMVSV	BPIFB2	196	Q8N4F0
PEPHTQARVYTTMTQ	AHNAK2	5526	Q8IVF2
SNVASQSMPPVYPSV	ANKHD1	1031	Q8IWZ3
TGNMTVLSPYLNTTV	APC	816	P25054
SIMYTLTSNIPEITP	ATP1A4	781	Q13733
TLTAPLYNTMVISQP	CLOCK	656	O15516
ATETQPIVYGQPQLM	CLTC	1626	Q00610
PNMTPEVVGEQVTSY	CNDP2	346	Q96KP4
RQDIMGTPVPETTLY	CNKSR2	521	Q8WXI2
TTQPTYTSQVMPKVV	UBN2	431	Q6ZU65
MSEVQPDSPQGIYDT	VPS11	611	Q9H270
FTYTVLVEMQPQPSV	TRPM6	856	Q9BX84
DTGTSLLTVPQQYMS	PGC	276	P20142
IYMQSVTSSLAPPVT	SLC5A10	441	A0PJK1
MSYIPGQPVTAVVQR	TAX1BP3	1	O14907
PPVGSSYQPMQTNVV	NFATC3	796	Q12968
IGNMNYPSTSPGSLV	RXRG	121	P48443
PNTMVSSVQGNTYPS	STAM	461	Q92783
ASSGVPMQTYPVQSH	STAM2	386	O75886
LPSTMQPGDDVVSNY	TEX261	151	Q6UWH6
SPEPMGINTSYLQSV	TMEM174	146	Q8WUU8
DSQVGTVNYMPPEAI	TTK	681	P33981
PYLPVTVVNTTMSLT	XPNPEP2	41	O43895
SVMPDIRNPEGTQYS	TOX	136	O94900
LQPYMPTVSATIQAQ	MARS1	756	P56192
SMPTTGYSAVPANII	HIVEP1	841	P15822
QVPPMETSQPYEEVS	PPIP5K1	1241	Q6PFW1
PSEILSDYIQQSTMG	VWA3A	276	A6NCI4
LEITDNPYMTSIPVN	TSHR	156	P16473
SVVVNMPAQALYASP	KLHL29	216	Q96CT2
PSMAFGVQYPTSVNI	LAMC3	106	Q9Y6N6