Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionserine-type peptidase activity

TPP2 CELA2A NUP98 KLK14 CELA2B TMPRSS11F PRCP TPSG1

1.19e-052071038GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

TPP2 CELA2A NUP98 KLK14 CELA2B TMPRSS11F PRCP TPSG1

1.42e-052121038GO:0017171
GeneOntologyMolecularFunctioninositol 1,4,5-trisphosphate-gated calcium channel activity

ITPR1 ITPR3

7.88e-0531032GO:0005220
GeneOntologyMolecularFunctiontransforming growth factor beta receptor activity, type I

BMPR1A BMPR1B

2.61e-0451032GO:0005025
GeneOntologyMolecularFunctionserine-type endopeptidase activity

TPP2 CELA2A KLK14 CELA2B TMPRSS11F TPSG1

4.57e-041901036GO:0004252
GeneOntologyMolecularFunctionBMP receptor activity

BMPR1A BMPR1B

7.23e-0481032GO:0098821
GeneOntologyBiologicalProcessreceptor-mediated endocytosis of virus by host cell

EPS15 KIAA0319L SIGLEC1

2.57e-05121033GO:0019065
GeneOntologyBiologicalProcessendocytosis involved in viral entry into host cell

EPS15 KIAA0319L SIGLEC1

4.23e-05141033GO:0075509
DomainInsP3_rcpt-bd

ITPR1 ITPR3

8.83e-0531022IPR000493
DomainLatrophilin

ADGRL2 ADGRL3

8.83e-0531022PF02354
DomainGPCR_2_latrophilin_rcpt_C

ADGRL2 ADGRL3

8.83e-0531022IPR003334
DomainARM-type_fold

ZYG11A IPO8 INTS1 TMCO6 ITPR1 IQCB1 IFRD2 TERB1 UNC79

1.00e-043391029IPR016024
DomainTRYPSIN_HIS

CELA2A KLK14 CELA2B TMPRSS11F TPSG1

2.52e-041031025IPR018114
DomainTRYPSIN_SER

CELA2A KLK14 CELA2B TMPRSS11F TPSG1

2.88e-041061025PS00135
DomainGPCR_2_latrophilin

ADGRL2 ADGRL3

2.92e-0451022IPR003924
DomainLectin_gal-bd_dom

ADGRL2 ADGRL3

2.92e-0451022IPR000922
DomainGal_Lectin

ADGRL2 ADGRL3

2.92e-0451022PF02140
DomainSUEL_LECTIN

ADGRL2 ADGRL3

2.92e-0451022PS50228
DomainTRYPSIN_HIS

CELA2A KLK14 CELA2B TMPRSS11F TPSG1

3.01e-041071025PS00134
DomainPeptidase_S1A

CELA2A KLK14 CELA2B TMPRSS11F TPSG1

3.87e-041131025IPR001314
DomainTRYPSIN_DOM

CELA2A KLK14 CELA2B TMPRSS11F TPSG1

4.20e-041151025PS50240
DomainRIH_assoc

ITPR1 ITPR3

4.37e-0461022PF08454
DomainRIH_assoc-dom

ITPR1 ITPR3

4.37e-0461022IPR013662
DomainRIH_dom

ITPR1 ITPR3

4.37e-0461022IPR000699
DomainIns145_P3_rcpt

ITPR1 ITPR3

4.37e-0461022IPR014821
DomainRyanodine_recept-rel

ITPR1 ITPR3

4.37e-0461022IPR015925
Domain-

ITPR1 ITPR3

4.37e-04610221.25.10.30
DomainRYDR_ITPR

ITPR1 ITPR3

4.37e-0461022PF01365
DomainIns145_P3_rec

ITPR1 ITPR3

4.37e-0461022PF08709
DomainTryp_SPc

CELA2A KLK14 CELA2B TMPRSS11F TPSG1

4.55e-041171025SM00020
DomainTrypsin

CELA2A KLK14 CELA2B TMPRSS11F TPSG1

5.30e-041211025PF00089
DomainTrypsin_dom

CELA2A KLK14 CELA2B TMPRSS11F TPSG1

5.30e-041211025IPR001254
DomainPeptidase_S1_PA

CELA2A KLK14 CELA2B TMPRSS11F TPSG1

5.71e-041231025IPR009003
DomainGS

BMPR1A BMPR1B

6.09e-0471022SM00467
DomainGS_dom

BMPR1A BMPR1B

6.09e-0471022IPR003605
DomainGS

BMPR1A BMPR1B

6.09e-0471022PS51256
DomainTGF_beta_GS

BMPR1A BMPR1B

6.09e-0471022PF08515
DomainGPS

ADGRV1 ADGRL2 ADGRL3

8.37e-04341023SM00303
DomainGPS

ADGRV1 ADGRL2 ADGRL3

9.12e-04351023PF01825
DomainGPS

ADGRV1 ADGRL2 ADGRL3

9.91e-04361023PS50221
DomainGPS

ADGRV1 ADGRL2 ADGRL3

1.07e-03371023IPR000203
DomainMIR

ITPR1 ITPR3

1.29e-03101022PS50919
DomainMIR

ITPR1 ITPR3

1.29e-03101022PF02815
DomainMIR

ITPR1 ITPR3

1.29e-03101022SM00472
DomainActivin_recp

BMPR1A BMPR1B

1.29e-03101022IPR000472
DomainMIR_motif

ITPR1 ITPR3

1.29e-03101022IPR016093
DomainActivin_recp

BMPR1A BMPR1B

1.29e-03101022PF01064
DomainG_PROTEIN_RECEP_F2_1

ADGRV1 ADGRL2 ADGRL3

1.35e-03401023PS00649
DomainGPCR_2_extracellular_dom

ADGRV1 ADGRL2 ADGRL3

1.35e-03401023IPR001879
DomainG_PROTEIN_RECEP_F2_3

ADGRV1 ADGRL2 ADGRL3

1.35e-03401023PS50227
DomainTRYPSIN_SER

CELA2A KLK14 CELA2B TMPRSS11F

1.50e-03901024IPR033116
DomainGAIN_dom_N

ADGRL2 ADGRL3

1.57e-03111022IPR032471
DomainGAIN

ADGRL2 ADGRL3

1.57e-03111022PF16489
DomainF-box-like

FBXO48 FBXO24 FBXO41

1.78e-03441023PF12937
DomainTGFB_receptor

BMPR1A BMPR1B

1.88e-03121022IPR000333
DomainOLF

ADGRL2 ADGRL3

2.22e-03131022PS51132
DomainOlfac-like_dom

ADGRL2 ADGRL3

2.22e-03131022IPR003112
DomainOLF

ADGRL2 ADGRL3

2.22e-03131022SM00284
DomainOLF

ADGRL2 ADGRL3

2.22e-03131022PF02191
DomainCUB

MEGF8 LRP3 SEZ6L

2.43e-03491023PF00431
DomainG_PROTEIN_RECEP_F2_2

ADGRV1 ADGRL2 ADGRL3

2.57e-03501023PS00650
Domain7tm_2

ADGRV1 ADGRL2 ADGRL3

2.57e-03501023PF00002
DomainCUB

MEGF8 LRP3 SEZ6L

2.57e-03501023SM00042
Domain-

MEGF8 LRP3 SEZ6L

2.88e-035210232.60.120.290
DomainCUB

MEGF8 LRP3 SEZ6L

3.04e-03531023PS01180
DomainIon_trans_dom

KCNH8 ITPR1 ITPR3 NALCN

3.53e-031141024IPR005821
DomainIon_trans

KCNH8 ITPR1 ITPR3 NALCN

3.53e-031141024PF00520
DomainARM-like

ZYG11A IPO8 TMCO6 IQCB1 IFRD2 TERB1

3.65e-032701026IPR011989
DomainCUB_dom

MEGF8 LRP3 SEZ6L

3.74e-03571023IPR000859
DomainPP2C

PPM1J TAB1

3.81e-03171022IPR015655
DomainGPCR_2_secretin-like

ADGRV1 ADGRL2 ADGRL3

4.32e-03601023IPR000832
DomainGPCR_2-like

ADGRV1 ADGRL2 ADGRL3

4.32e-03601023IPR017981
DomainG_PROTEIN_RECEP_F2_4

ADGRV1 ADGRL2 ADGRL3

4.52e-03611023PS50261
DomainPP2C

PPM1J TAB1

4.75e-03191022PF00481
DomainPP2Cc

PPM1J TAB1

5.26e-03201022SM00332
DomainPPM-type_phosphatase_dom

PPM1J TAB1

5.26e-03201022IPR001932
Domain-

PPM1J TAB1

5.26e-032010223.60.40.10
DomainPPM_2

PPM1J TAB1

5.26e-03201022PS51746
Pubmed

Mutational analysis of the ligand binding site of the inositol 1,4,5-trisphosphate receptor.

ITPR1 ITPR3

8.86e-06210428663526
Pubmed

Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development.

BMPR1A BMPR1B

8.86e-062104215102710
Pubmed

The Pro335 --> Leu polymorphism of type 3 inositol 1,4,5-trisphosphate receptor found in mouse inbred lines results in functional change.

ITPR1 ITPR3

8.86e-062104215890645
Pubmed

Elastase-2, a Tissue Alternative Pathway for Angiotensin II Generation, Plays a Role in Circulatory Sympathovagal Balance in Mice.

CELA2A CELA2B

8.86e-062104228386233
Pubmed

Assignment of the BMPR1A and BMPR1B genes to human chromosome 10q22.3 and 4q23-->q24 byin situ hybridization and radiation hybrid map ping.

BMPR1A BMPR1B

8.86e-06210429730621
Pubmed

Expression of bone morphogenetic protein receptors type-IA, -IB and -II correlates with tumor grade in human prostate cancer tissues.

BMPR1A BMPR1B

8.86e-062104210850425
Pubmed

Differential molecular regulation of processing and membrane expression of Type-I BMP receptors: implications for signaling.

BMPR1A BMPR1B

8.86e-062104228357470
Pubmed

Inactivity of recombinant ELA2B provides a new example of evolutionary elastase silencing in humans.

CELA2A CELA2B

8.86e-062104216327289
Pubmed

Distinct roles of BMP receptors Type IA and IB in osteo-/chondrogenic differentiation in mesenchymal progenitors (C3H10T1/2).

BMPR1A BMPR1B

8.86e-062104215322331
Pubmed

Three additional inositol 1,4,5-trisphosphate receptors: molecular cloning and differential localization in brain and peripheral tissues.

ITPR1 ITPR3

8.86e-06210421374893
Pubmed

Latrophilin GPCRs direct synapse specificity by coincident binding of FLRTs and teneurins.

ADGRL2 ADGRL3

8.86e-062104230792275
Pubmed

Myeloma cells self-promote migration by regulating TAB1-driven TIMP-1 expression in mesenchymal stem cells.

TIMP1 TAB1

8.86e-062104233183761
Pubmed

BMPR1A and BMPR1B Missense Mutations Cause Primary Ovarian Insufficiency.

BMPR1A BMPR1B

8.86e-062104231769494
Pubmed

Characterization of pancreatic elastase II cDNAs: two elastase II mRNAs are expressed in human pancreas.

CELA2A CELA2B

8.86e-06210423646943
Pubmed

BMPR1A is necessary for chondrogenesis and osteogenesis, whereas BMPR1B prevents hypertrophic differentiation.

BMPR1A BMPR1B

8.86e-062104232764110
Pubmed

[BMP7 signaling via BMPR1A, BMPR1B inhibits the proliferation of lung large carcinoma NCI-H460 cell].

BMPR1A BMPR1B

8.86e-062104220673479
Pubmed

Tyr-167/Trp-168 in type 1/3 inositol 1,4,5-trisphosphate receptor mediates functional coupling between ligand binding and channel opening.

ITPR1 ITPR3

8.86e-062104220813840
Pubmed

Heteroligomers of type-I and type-III inositol trisphosphate receptors in WB rat liver epithelial cells.

ITPR1 ITPR3

8.86e-06210427559486
Pubmed

Latrophilin GPCR signaling mediates synapse formation.

ADGRL2 ADGRL3

8.86e-062104233646123
Pubmed

Structural studies of inositol 1,4,5-trisphosphate receptor: coupling ligand binding to channel gating.

ITPR1 ITPR3

8.86e-062104220843799
Pubmed

Distinct roles of inositol 1,4,5-trisphosphate receptor types 1 and 3 in Ca2+ signaling.

ITPR1 ITPR3

8.86e-062104214707143
Pubmed

Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins.

ITPR1 ITPR3

2.65e-053104210874040
Pubmed

A family of heptahelical receptors with adhesion-like domains: a marriage between two super families.

ADGRL2 ADGRL3

2.65e-053104210994649
Pubmed

Expression of inositol 1,4,5-trisphosphate receptors in mouse oocytes and early embryos: the type I isoform is upregulated in oocytes and downregulated after fertilization.

ITPR1 ITPR3

2.65e-05310429808793
Pubmed

Mutations in UNC80, Encoding Part of the UNC79-UNC80-NALCN Channel Complex, Cause Autosomal-Recessive Severe Infantile Encephalopathy.

NALCN UNC79

2.65e-053104226708753
Pubmed

Role of type I receptors for anti-Müllerian hormone in the SMAT-1 Sertoli cell line.

BMPR1A BMPR1B

2.65e-053104215897891
Pubmed

Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.

ITPR1 ITPR3

2.65e-053104220395455
Pubmed

Macrophage metalloelastase (MMP12) regulates adipose tissue expansion, insulin sensitivity, and expression of inducible nitric oxide synthase.

LARGE2 NOS2

2.65e-053104224914938
Pubmed

Nitric oxide synthase and breast cancer: role of TIMP-1 in NO-mediated Akt activation.

TIMP1 NOS2

2.65e-053104222957045
Pubmed

The multiple actions of black widow spider toxins and their selective use in neurosecretion studies.

ADGRL2 ADGRL3

2.65e-053104215066411
Pubmed

Identification of KRAP-expressing cells and the functional relevance of KRAP to the subcellular localization of IP3R in the stomach and kidney.

ITPR1 ITPR3

2.65e-053104222992961
Pubmed

Soluble LR11/SorLA represses thermogenesis in adipose tissue and correlates with BMI in humans.

BMPR1A BMPR1B

2.65e-053104226584636
Pubmed

Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.

ITPR1 ITPR3

2.65e-053104217437169
Pubmed

Age-Associated Increase in BMP Signaling Inhibits Hippocampal Neurogenesis.

BMPR1A BMPR1B

2.65e-053104225538007
Pubmed

Genetic variants in components of the NALCN-UNC80-UNC79 ion channel complex cause a broad clinical phenotype (NALCN channelopathies).

NALCN UNC79

2.65e-053104230167850
Pubmed

Dendrite complexity of sympathetic neurons is controlled during postnatal development by BMP signaling.

BMPR1A BMPR1B

2.65e-053104224048844
Pubmed

Distinct developmental programs require different levels of Bmp signaling during mouse retinal development.

BMPR1A BMPR1B

2.65e-053104215673568
Pubmed

Type 2 and type 3 inositol 1,4,5-trisphosphate (IP3) receptors promote the differentiation of granule cell precursors in the postnatal cerebellum.

ITPR1 ITPR3

2.65e-053104218194433
Pubmed

Expression of bone morphogenetic protein receptors in the developing mouse metanephros.

BMPR1A BMPR1B

2.65e-053104211701996
Pubmed

Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.

ITPR1 ITPR3

2.65e-053104218547250
Pubmed

Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population.

ITPR1 ITPR3

2.65e-053104236350267
Pubmed

Identification of a family of calcium sensors as protein ligands of inositol trisphosphate receptor Ca(2+) release channels.

ITPR1 ITPR3

2.65e-053104212032348
Pubmed

IP3 receptors regulate vascular smooth muscle contractility and hypertension.

ITPR1 ITPR3

2.65e-053104227777977
Pubmed

The versatility and universality of calcium signalling.

ITPR1 ITPR3

2.65e-053104211413485
Pubmed

Murine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolism.

OBSCN BMPR1B

2.65e-053104231098411
Pubmed

Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR3

2.65e-053104226009177
Pubmed

Differential inositol 1,4,5-trisphosphate receptor signaling in a neuronal cell line.

ITPR1 ITPR3

2.65e-053104217581770
Pubmed

Predominant role of type 1 IP3 receptor in aortic vascular muscle contraction.

ITPR1 ITPR3

2.65e-053104218241669
Pubmed

Expression patterns of BMPRs in the developing mouse molar.

BMPR1A BMPR1B

2.65e-053104216432712
Pubmed

Analysis of the native murine bone morphogenetic protein serine threonine kinase type I receptor (ALK-3).

BMPR1A BMPR1B

2.65e-05310428707881
Pubmed

Receptor-activated single channels in intact human platelets.

ITPR1 ITPR3

2.65e-05310421693919
Pubmed

Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca2+ mobilization.

ITPR1 ITPR3

2.65e-053104219068129
Pubmed

Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.

ITPR1 ITPR3

2.65e-053104223955339
Pubmed

Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.

ITPR1 ITPR3

2.65e-053104231979185
Pubmed

The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways.

BMPR1A BMPR1B

2.65e-053104211714695
Pubmed

Transdifferentiation of alveolar epithelial type II to type I cells is controlled by opposing TGF-β and BMP signaling.

BMPR1A BMPR1B

2.65e-053104223831617
Pubmed

Knockdown of FLT4, Nup98, and Nup205 Cellular Genes Effectively Suppresses the Reproduction of Influenza Virus Strain A/WSN/1933 (H1N1) In vitro.

NUP98 NUP205

2.65e-053104235339191
Pubmed

Tsg101 regulates PI(4,5)P2/Ca(2+) signaling for HIV-1 Gag assembly.

ITPR1 ITPR3

2.65e-053104224904548
Pubmed

Ubiquitination and proteasomal degradation of endogenous and exogenous inositol 1,4,5-trisphosphate receptors in alpha T3-1 anterior pituitary cells.

ITPR1 ITPR3

2.65e-053104212421829
Pubmed

The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development.

BMPR1A BMPR1B

2.65e-053104225413979
Pubmed

Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR3

2.65e-053104217327232
Pubmed

Granulosa cell-expressed BMPR1A and BMPR1B have unique functions in regulating fertility but act redundantly to suppress ovarian tumor development.

BMPR1A BMPR1B

2.65e-053104220363875
Pubmed

The transforming growth factor-beta type III receptor mediates distinct subcellular trafficking and downstream signaling of activin-like kinase (ALK)3 and ALK6 receptors.

BMPR1A BMPR1B

2.65e-053104219726563
Pubmed

Primary structure of human pancreatic elastase 2 determined by sequence analysis of the cloned mRNA.

CELA2A CELA2B

2.65e-05310423427074
Pubmed

Nuclear inositol 1,4,5-trisphosphate receptors regulate local Ca2+ transients and modulate cAMP response element binding protein phosphorylation.

ITPR1 ITPR3

2.65e-053104216014380
Pubmed

BMP signaling specifies the development of a large and fast CNS synapse.

BMPR1A BMPR1B

2.65e-053104223708139
Pubmed

Distinct spatial and temporal expression patterns of two type I receptors for bone morphogenetic proteins during mouse embryogenesis.

BMPR1A BMPR1B

2.65e-05310427750489
Pubmed

BMPR1a and BMPR1b signaling exert opposing effects on gliosis after spinal cord injury.

BMPR1A BMPR1B

2.65e-053104220130193
Pubmed

Knockdown of the type 2 and 3 inositol 1,4,5-trisphosphate receptors suppresses muscarinic antinociception in mice.

ITPR1 ITPR3

2.65e-053104217890015
Pubmed

Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis.

ITPR1 ITPR3

2.65e-053104218250332
Pubmed

Inositol 1, 4, 5-trisphosphate receptors and human left ventricular myocytes.

ITPR1 ITPR3

2.65e-053104223983250
Pubmed

Differential distribution of inositol trisphosphate receptor isoforms in mouse oocytes.

ITPR1 ITPR3

2.65e-05310429858485
Pubmed

Extracellular calcium controls background current and neuronal excitability via an UNC79-UNC80-NALCN cation channel complex.

NALCN UNC79

2.65e-053104221040849
Pubmed

Activation of the inositol (1,4,5)-triphosphate calcium gate receptor is required for HIV-1 Gag release.

ITPR1 ITPR3

2.65e-053104220427533
Pubmed

Intellectual disability-associated UNC80 mutations reveal inter-subunit interaction and dendritic function of the NALCN channel complex.

NALCN UNC79

2.65e-053104232620897
Pubmed

Bone morphogenetic protein type IB receptor is progressively expressed in malignant glioma tumours.

BMPR1A BMPR1B

2.65e-05310428605097
Pubmed

alpha-Latrotoxin and its receptors: neurexins and CIRL/latrophilins.

ADGRL2 ADGRL3

2.65e-053104211520923
Pubmed

MiR-29a reduces TIMP-1 production by dermal fibroblasts via targeting TGF-β activated kinase 1 binding protein 1, implications for systemic sclerosis.

TIMP1 TAB1

2.65e-053104225549087
Pubmed

Enhanced expression of type I receptors for bone morphogenetic proteins during bone formation.

BMPR1A BMPR1B

2.65e-05310428592941
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

HSD17B7 NAA60 ICE2 INTS1 MFSD4A IL23A SLC22A12 GLMP LRRC25 XKR5 PLXNA2 SEZ6L

3.95e-059851041212975309
Pubmed

Loss of IP3R-dependent Ca2+ signalling in thymocytes leads to aberrant development and acute lymphoblastic leukemia.

ITPR1 ITPR3

5.29e-054104225215520
Pubmed

Bone morphogenetic protein 4 (BMP4) signaling in retinoblastoma cells.

BMPR1A BMPR1B

5.29e-054104221152263
Pubmed

Oligomeric interactions of TGF-β and BMP receptors.

BMPR1A BMPR1B

5.29e-054104222293501
Pubmed

Bone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptors.

BMPR1A BMPR1B

5.29e-054104210712517
Pubmed

Inositol 1, 4, 5-trisphosphate receptor interacts with the SNARE domain of syntaxin 1B.

ITPR1 ITPR3

5.29e-054104221424589
Pubmed

Bone morphogenetic proteins, eye patterning, and retinocollicular map formation in the mouse.

BMPR1A BMPR1B

5.29e-054104218614674
Pubmed

Latrophilin-2 and latrophilin-3 are redundantly essential for parallel-fiber synapse function in cerebellum.

ADGRL2 ADGRL3

5.29e-054104232202499
Pubmed

Common genetic variants of the BMP4, BMPR1A, BMPR1B, and ACVR1 genes, left ventricular mass, and other parameters of the heart in newborns.

BMPR1A BMPR1B

5.29e-054104222971142
Pubmed

BRAM1, a BMP receptor-associated molecule involved in BMP signalling.

BMPR1A TAB1

5.29e-05410429663660
Pubmed

Nitric oxide-mediated regulation of β-amyloid clearance via alterations of MMP-9/TIMP-1.

TIMP1 NOS2

5.29e-054104223016931
Pubmed

Effect of bone morphogenetic protein-6 on haemopoietic stem cells and cytokine production in normal human bone marrow stroma.

BMPR1A BMPR1B

5.29e-054104211401330
Pubmed

HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression.

BMPR1A BMPR1B

5.29e-054104224904118
Pubmed

LTP of inhibition at PV interneuron output synapses requires developmental BMP signaling.

BMPR1A BMPR1B

5.29e-054104232572071
Pubmed

Loss of IP3 Receptor-Mediated Ca2+ Release in Mouse B Cells Results in Abnormal B Cell Development and Function.

ITPR1 ITPR3

5.29e-054104228615414
Pubmed

Mutations in the BMP pathway in mice support the existence of two molecular classes of holoprosencephaly.

BMPR1A BMPR1B

5.29e-054104217913790
Pubmed

Distinct localization and function of (1,4,5)IP(3) receptor subtypes and the (1,3,4,5)IP(4) receptor GAP1(IP4BP) in highly purified human platelet membranes.

ITPR1 ITPR3

5.29e-054104210828023
Pubmed

The Bcl-2 protein family member Bok binds to the coupling domain of inositol 1,4,5-trisphosphate receptors and protects them from proteolytic cleavage.

ITPR1 ITPR3

5.29e-054104223884412
Pubmed

Exome sequencing in seven families and gene-based association studies indicate genetic heterogeneity and suggest possible candidates for fibromuscular dysplasia.

OBSCN RNF213

5.29e-054104226147384
Pubmed

Regulation of InsP3 receptor activity by neuronal Ca2+-binding proteins.

ITPR1 ITPR3

5.29e-054104214685260
Pubmed

Synergistic effects of different bone morphogenetic protein type I receptors on alkaline phosphatase induction.

BMPR1A BMPR1B

5.29e-054104211282024
Cytoband3q13.33

IQCB1 GPR156 POLQ

4.39e-053010433q13.33
CytobandEnsembl 112 genes in cytogenetic band chr13q33

TPP2 CCDC168 NALCN

2.72e-04551043chr13q33
GeneFamilyInositol 1,4,5-triphosphate receptors|Protein phosphatase 1 regulatory subunits

ITPR1 ITPR3

4.55e-053712297
GeneFamilyAdhesion G protein-coupled receptors, subfamily L

ADGRL2 ADGRL3

9.08e-054712918
GeneFamilyType 1 receptor serine/threonine kinases

BMPR1A BMPR1B

3.15e-047712345
GeneFamilyCyclins|F-boxes other

FBXO48 FBXO24 FBXO41

4.79e-0439713560
GeneFamilyADAM metallopeptidase domain containing|CD molecules

BMPR1A BMPR1B SIGLEC1 NCR2 LY9 CD96 IL9R

8.87e-04394717471
CoexpressionGSE6259_CD4_TCELL_VS_CD8_TCELL_DN

RNF135 WRN NUP98 ITPR1 TAF3 PRCP NLRC5 LY9

6.82e-071841038M6739
CoexpressionGSE9037_CTRL_VS_LPS_1H_STIM_BMDM_DN

HSD17B7 GRWD1 STK17B GART GADD45A TPSG1 MMUT

1.45e-052001037M5801
ToppCellLPS_only-Hematopoietic_Mast-Mast_cells-T-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KLHL6 STK17B GALR2 BMPR1B CD96 IL9R

1.36e-061501036ccb782fbcb3122266354a112a9a850506664f44d
ToppCellLPS_only-Hematopoietic_Mast-Mast_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KLHL6 STK17B GALR2 BMPR1B CD96 IL9R

1.36e-0615010367290e9a812b1b2f919e67ccde0acf52687ab138f
ToppCellLPS_only-Hematopoietic_Mast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KLHL6 STK17B GALR2 BMPR1B CD96 IL9R

1.36e-0615010362c5078a1f769ba8153dee756b53d28eb7b434a96
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Mast-Mast_cells-T-cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KLHL6 STK17B GALR2 BMPR1B CD96 IL9R

1.41e-061511036b85a763459a0f019d1f9975d09b9f2247d62c9d3
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBXO48 CDKN3 ZWILCH LY9 POLQ XKR5

2.91e-0617110361eebd7138c3b20ddc1104f21615f9df0e776bbe6
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFN1 ABCA12 OBSCN ADGRV1 UNC79 ADGRL3

4.44e-0618410362cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFN1 ABCA12 OBSCN ADGRV1 UNC79 ADGRL3

4.44e-061841036ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGFN1 ABCA12 OBSCN ADGRV1 UNC79 ADGRL3

4.44e-0618410362b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell15-Distal-Immune-Hematopoietic,_T_Cells|Distal / Age, Tissue, Lineage and Cell class

KLHL6 STK17B ASB15 LY9 CD96 RGL4

4.58e-061851036481e3d3b63f2e5b4783088523c3cf70a461aed27
ToppCellwk_20-22-Hematologic_Lymphocytic-T_&_ILC-ILC3|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

KLHL6 STK17B IL23A NCR2 CD96 RGL4

4.72e-061861036ac1d2a94674bd15885e70502abad3a2ff3c21d73
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC-ILC3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

STK17B IL23A NCR2 LY9 CD96 RGL4

4.87e-061871036a037631a01d2cce088e6522dceeb1eee806522a1
ToppCell18-Airway-Immune-Immune|Airway / Age, Tissue, Lineage and Cell class

STK17B IL23A NLRC5 LY9 CD96 RGL4

5.33e-06190103609e6bbe4f1be48153dc6cd647a57a0b531b8bf99
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAGI1 MFSD4A GALNT18 PRCP ADGRL2 ADGRL3

5.83e-0619310366e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAGI1 MFSD4A GALNT18 PRCP ADGRL2 ADGRL3

5.83e-061931036af5108260783e69a7d67896c5bf64f862525926d
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAGI1 MFSD4A GALNT18 PRCP ADGRL2 ADGRL3

6.01e-0619410360b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-SELL+_CD8_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STK17B RNF213 NLRC5 LY9 CD96 RGL4

6.75e-0619810360dac00a64fe08ec6669af3ddd4b82413b673233d
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

STK17B IL23A LY9 CD96 IL9R RGL4

6.95e-061991036c9e1ac9f0fba23250a5df4052559d18d16df4521
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MFSD4A RNF213 GALNT18 PRCP ADGRL2 ADGRL3

7.15e-062001036dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MFSD4A RNF213 GALNT18 PRCP ADGRL2 ADGRL3

7.15e-062001036a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCellLPS_IL1RA_TNF-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MFSD4A RNF213 GALNT18 PRCP ADGRL2 ADGRL3

7.15e-062001036d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GLMP BMPR1B GPR156 POLQ ADGRL2

1.99e-051421035e160f35b3c18e77c4107fe96db5f56227c91785e
ToppCellLPS-antiTNF-Hematopoietic_Mast-Mast_cells-T-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KLHL6 STK17B BMPR1B CD96 IL9R

2.35e-0514710351ecd7c084e73eb6fae1ab1f9aae17115d3d62cbd
ToppCellLPS-antiTNF-Hematopoietic_Mast-Mast_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KLHL6 STK17B BMPR1B CD96 IL9R

2.51e-05149103559aa1f2a5cbeba64c4529fb05f544db17fd8b188
ToppCellLPS-antiTNF-Hematopoietic_Mast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KLHL6 STK17B BMPR1B CD96 IL9R

2.51e-0514910351527cdd98a2734cbf8ce4c6170557280b71c55cb
ToppCellDividing_Macrophages-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

CDKN3 CELA2A CELA2B IL23A POLQ

2.76e-051521035e39cfc346b35235546b303e7d73e4d9d7120a5fb
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBXO41 NCR2 CD96 IL9R RGL4

2.94e-051541035d2aa24c593a1c0c6f186b74a18438b64b4e59701
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGI1 ADGRV1 PPM1J GALNT18 NLRC5

3.03e-051551035c58a5fb8d853f12204e961d633e83452eb12a659
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGI1 ADGRV1 PPM1J GALNT18 NLRC5

3.03e-0515510359cb8c42c2e451b2d4dcd7154a4b1bfd21bbb7ea8
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

HUS1B SH3D19 NLRC5 CD96 RGL4

3.53e-0516010358aaf6ac4f33ea291387fdbf9ff1a91d559391774
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK17B PPM1J NLRC5 LY9 CD96

3.53e-0516010359e238e7cb31070a5b9da73b4bfddde54b969b0fd
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK17B PPM1J NLRC5 LY9 CD96

3.53e-0516010353a5a7984d9ffcb0fbada02b95ffd7aca091acf30
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK17B PPM1J NLRC5 LY9 CD96

3.53e-05160103532a105b99fc565c944672f518d6947dcf9ea8832
ToppCellfacs-Pancreas-Exocrine-18m-Hematologic-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK17B NLRC5 SLC36A3 LY9 TPSG1

3.64e-05161103516f77e7a5444d2f2b210362816cd7a07b9b42af6
ToppCellfacs-Pancreas-Exocrine-18m-Hematologic|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK17B NLRC5 SLC36A3 LY9 TPSG1

3.64e-051611035f5821f551cf5c64c9f75cdb723492c87aac1ece0
ToppCellfacs-Pancreas-Exocrine-18m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK17B NLRC5 SLC36A3 LY9 TPSG1

3.64e-05161103558a32a1033f379579697bda1bbf047a088e4a34f
ToppCell343B-Lymphocytic-ILC|343B / Donor, Lineage, Cell class and subclass (all cells)

KLHL6 NUP205 FGFBP3 TAB1 IL9R

4.21e-051661035a54377c703efff42d2cc1a8fdb610facc58053dd
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 ADGRV1 NALCN TIMP1 UNC79

4.58e-05169103512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

BMPR1A TPSG1 ADGRL2 NOS2 ADGRL3

4.71e-051701035a6fa0cab1fa829ec601fe48306b4c43c83425b04
ToppCell390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

BMPR1A TPSG1 ADGRL2 NOS2 ADGRL3

4.71e-051701035b40255eee45eb18b5a297336d7f3845fd8f8aa3b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HUS1B STK17B NLRC5 LY9 CD96

4.71e-051701035c4f00c1acde1d3b521101e469101d10fd257653e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HUS1B STK17B NLRC5 LY9 CD96

4.71e-051701035d3c1edaf0190d8927578043c372dba7477e75e14
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122|Adult / Lineage, Cell type, age group and donor

ABCA12 OBSCN GALNT18 ADGRL2 PLXNA2

4.85e-051711035bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCellfacs-GAT-Fat-24m-Epithelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNH8 OBSCN ADGRV1 C16orf46 TPSG1

5.12e-051731035815ba48a9222ea09ba8005e2d2f7c5addf118ad1
ToppCellfacs-GAT-Fat-24m-Epithelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNH8 OBSCN ADGRV1 C16orf46 TPSG1

5.12e-05173103598e464d9e6d6b69421e9e4041b638b6825247f60
ToppCellfacs-GAT-Fat-24m-Epithelial-epithelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNH8 OBSCN ADGRV1 C16orf46 TPSG1

5.12e-0517310353e6f0a08eddfd61871f7a85acccf6d539af6ebda
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HUS1B VPS13C RPUSD1 GALNT18 SEZ6L

5.26e-051741035f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-NK_T_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STK17B LRRC25 NCR2 CD96 RGL4

5.56e-051761035dbc4f64cd39b229f2355ca1d0215cc7f6a767dce
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-NK_T_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRRC25 NLRC5 CD96 IL9R RGL4

5.56e-0517610351ea45cf7b7e12206c3eca1594173368643c50e59
ToppCellControl-Lymphocytic_NKT-T_cells-T-cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KLHL6 STK17B IL23A BMPR1B CD96

5.86e-051781035910f8bea19d335455aba24e6a07b4834b709db5d
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KLHL6 CCDC168 LRRC25 SIGLEC1 LY9

6.02e-051791035716856b2c7c660bf5ce00e63efeda6ed121f2baa
ToppCellControl-Lymphocytic_NKT-T_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KLHL6 STK17B IL23A BMPR1B CD96

6.02e-051791035d892d9496f1c33e23312092591eb2e968e736f7d
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR-_ILC3|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STK17B IL23A LRRC25 CD96 RGL4

6.18e-0518010353f0a692ad2823951e0ec23d0452f436c5f5c09c0
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

GALNT18 ADGRL2 NOS2 PLXNA2 ADGRL3

6.34e-051811035c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-SELL+_CD4_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STK17B IL23A LY9 CD96 RGL4

6.51e-0518210357dd435e456da1470d19d3db307ae4909c25d2f0d
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STK17B RNF213 NCR2 LY9 CD96

6.51e-05182103509d0793245d3d77ab5fc384c0b62637f736da50b
ToppCellCOVID-19-Epithelial_cells-ECM-high_epithelial|COVID-19 / group, cell type (main and fine annotations)

MAGI1 ADGRV1 TAS2R7 TIMP1 PLXNA2

6.68e-051831035dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR-_ILC3|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KLHL6 LRRC25 NCR2 CD96 RGL4

6.68e-0518310352c0b1265af2bca2c378ff7104bce337c98053b5e
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL23A LRRC25 NCR2 CD96 RGL4

6.68e-051831035c7fedb5b0c1f17b3391ce1c4a6bfca7615c359c5
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL23A LRRC25 NCR2 LY9 CD96

6.68e-051831035d4a558bc0b8e11be195a7da1468ab38eb477117d
ToppCellwk_08-11-Hematologic_Lymphocytic-T_&_ILC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

NCR2 LY9 CD96 IL9R RGL4

6.86e-05184103551ae0963b4fb034c3f605ee4e5da513cba7aca35
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-SELL+_CD8_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STK17B IL23A LY9 CD96 RGL4

6.86e-051841035c80acd6a81a3633d72813a77223879d0be254f93
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-ILCP|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL23A NCR2 LY9 CD96 RGL4

7.22e-051861035428b4cbee3d3ab666cab2fc2d9c815318359e458
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RNF213 GALNT18 NLRC5 ADGRL2 ADGRL3

7.40e-051871035f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL23A NLRC5 NCR2 CD96 RGL4

7.40e-05187103542b20d7f0a4f9195b3d71dc0e089b5e0914ebcbb
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 GALNT18 SH3D19 ADGRL2 ADGRL3

7.59e-051881035117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCell343B-Lymphocytic-ILC-ILC-1|343B / Donor, Lineage, Cell class and subclass (all cells)

KLHL6 NUP205 FGFBP3 TAB1 IL9R

7.59e-0518810358f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCelldroplet-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBXO48 CDKN3 ZWILCH POLQ XKR5

7.59e-0518810350ec2a1b0505501ba18f10a5fce68c306a6292419
ToppCell343B-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KLHL6 NUP205 FGFBP3 TAB1 IL9R

7.78e-051891035c26428871dc3261327d89cacaba6e21e004ff1f3
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(general)|COVID-19 / group, cell type (main and fine annotations)

MAGI1 GALNT18 ADGRL2 PLXNA2 ADGRL3

7.98e-051901035812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCellLPS-IL1RA+antiTNF-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MFSD4A GALNT18 PRCP ADGRL2 ADGRL3

8.38e-05192103504f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCellASK428-Immune-T_cell|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

STK17B RNF213 LY9 CD96 RGL4

8.38e-051921035121cb8c61002f20e1d287b8a7e67a30bb163e74a
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MFSD4A GALNT18 PRCP ADGRL2 ADGRL3

8.38e-051921035c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCell343B-Lymphocytic-ILC-ILC-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KLHL6 NUP205 FGFBP3 TAB1 IL9R

8.38e-051921035445985fe1bcd33e4f0a1704b27988fbfc9334538
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR-_ILC3|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STK17B IL23A LRRC25 CD96 RGL4

8.59e-051931035d8e6a7f1da4506acaa06380b4aec3fe299ec8b7e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

STK17B RNF213 LY9 CD96 RGL4

8.59e-0519310357deb439943d35a4e825674b2b7dcddb45d366ad1
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MFSD4A GALNT18 PRCP SH3D19 ADGRL3

8.59e-051931035e1d546165dcc2392f540162206852c4717d7306f
ToppCellCOVID-19-Endothelial_cells-Inflamed_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

MAGI1 GALNT18 ADGRL2 PLXNA2 ADGRL3

8.59e-051931035979ebefa527f86bebeea5d94e626ee6c1cc7d53b
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRRC25 NCR2 LY9 CD96 RGL4

8.59e-051931035afdf92ecace145407d57192dde5d0dac0bc37ee9
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-C|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

STK17B ASB15 LY9 CD96 IL9R

8.59e-051931035bbe642f8b66ba9d028709deaf847f2f7e73be04f
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 GALNT18 SH3D19 ADGRL2 ADGRL3

8.80e-05194103571ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAGI1 GALNT18 PRCP ADGRL2 ADGRL3

8.80e-05194103543f92b0533e26633dc94cce554045d641ef8fd76
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LARGE2 STK17B RNF213 CD96 RGL4

8.80e-051941035c49f3341a19128855f084bcf18ef3da4bab79099
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAGI1 GALNT18 PRCP ADGRL2 ADGRL3

8.80e-0519410351d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCellLPS_only-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAGI1 GALNT18 PRCP ADGRL2 ADGRL3

8.80e-05194103558f069efdefa0366033764446b9d6ffd4a17807e
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STK17B NCR2 LY9 CD96 RGL4

8.80e-051941035da88e8c11e55df296d2533f1d1575779cdf3edd7
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAGI1 GALNT18 PRCP ADGRL2 ADGRL3

8.80e-051941035bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 OBSCN GALNT18 SH3D19 ADGRL2

8.80e-05194103540842a7160f337bfc191ee15fbda3e3d38a04c57
ToppCell3'-GW_trimst-1.5-SmallIntestine-Hematopoietic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STK17B NCR2 LY9 CD96 RGL4

9.01e-051951035441345d33f839a9e9222e790752b5603ff572bf2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 STK17B SIGLEC1 LY9 CD96

9.01e-0519510352d485373bfd9bb4bb9236bf0b31d03e132c8018f
ToppCell15-Airway-Immune-Hematopoietic,_T_Cells|Airway / Age, Tissue, Lineage and Cell class

STK17B NCR2 LY9 CD96 RGL4

9.01e-051951035ec392fc8bd2c0f1e3a79f2e401608fd6ba8d339c
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STK17B IL23A LY9 CD96 RGL4

9.23e-051961035ab6022041c33617bca3ed0c62f19673cd2750da9
ToppCell5'-Adult-SmallIntestine-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KLHL6 STK17B LRRC25 SIGLEC1 CD96

9.23e-051961035008e7593ab26988b957673f863bdd017516281ae
ToppCellCOVID-19-lung-Capillary_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

MAGI1 MFSD4A GALNT18 SH3D19 ADGRL2

9.23e-051961035ac28e9be288af6f00a841aea4ce4b99aed6b4505
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

STK17B RNF213 LY9 CD96 RGL4

9.46e-051971035d0962c94f4b07759b0c9dade75c39fd2deec2f21
ToppCellCOVID-19-lung-Capillary_1|lung / Disease (COVID-19 only), tissue and cell type

MAGI1 MFSD4A GALNT18 SH3D19 ADGRL2

9.46e-0519710357e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCellBAL-Control-cDC_5|Control / Compartment, Disease Groups and Clusters

KLHL6 GADD45A ITPR1 TIMP1 LY9

9.46e-0519710358a3fe59be3ed1f0254cc8c60b99c840193370efb
ToppCellBronchial-10x5prime-Immune_Lymphocytic-T-T_CD8-gdT|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NLRC5 NCR2 LY9 CD96 IL9R

9.69e-0519810359dc91a1101eef649a301f0147ecd5c028a9c2b12
ToppCellBronchial-10x5prime-Immune_Lymphocytic-T-T_CD4|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

STK17B IL23A LY9 CD96 RGL4

9.69e-0519810358d86b5c875d4663ea4d61f50a4eaff1883d97641
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

STK17B RNF213 LY9 CD96 RGL4

9.92e-051991035017d67582f80d90f20b3d02044fa2e32f3dff289
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC-CD4_T|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

STK17B IL23A LY9 CD96 RGL4

9.92e-051991035992bc4f0dc4189f18773c55976eb124c3827e08b
Diseasecarotid plaque build

KCNH8 EPG5 ITPR3 BMPR1B

1.80e-0484984EFO_0006501
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

ITPR1 ITPR3

7.05e-0412982DOID:1441 (implicated_via_orthology)
Diseasejuvenile polyposis syndrome (implicated_via_orthology)

BMPR1A BMPR1B

8.32e-0413982DOID:0050787 (implicated_via_orthology)
Diseasecystic fibrosis (is_marker_for)

TIMP1 NOS2 IL9R

1.17e-0362983DOID:1485 (is_marker_for)
DiseaseCannabis use

IPO8 CHID1

1.27e-0316982EFO_0007585
Diseasepulmonary hypertension (is_marker_for)

BMPR1A BMPR1B NOS2

1.28e-0364983DOID:6432 (is_marker_for)
DiseaseEye Abnormalities

BMPR1A BMPR1B

1.44e-0317982C0015393
DiseaseFemale Urogenital Diseases

BMPR1A TIMP1

1.61e-0318982C1720887
Diseasemucocutaneous lymph node syndrome

GALNT18 EPG5 PLXNA2

2.10e-0376983EFO_0004246
DiseaseDown syndrome (is_marker_for)

GART TIMP1

2.42e-0322982DOID:14250 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
LSQIAPLCWEQRNHS

ERVPABLB-1

206

P60509
WTQAKLESHSTPCSL

EPG5

1466

Q9HCE0
SLLAASNPSLVNNCW

nan

51

Q9N2K0
WLHSCDTNITTPKLE

ABCA12

601

Q86UK0
INAICSQWLPISHAV

EFL1

341

Q7Z2Z2
DLSNCSSPWVNHITQ

ADGRL3

546

Q9HAR2
PQTSLCLLWNQAAAS

ADGRV1

5851

Q8WXG9
HNTSLDQPCVKRWSA

ASB15

166

Q8WXK1
PDLSNCTSHWVNQLA

ADGRL2

516

O95490
SLIANSWVLTAAHCI

CELA2A

61

P08217
TECWAHNPASRLTAL

BMPR1B

471

O00238
CLWDTLVAPANSLVH

DMXL1

2866

Q9Y485
LTDPEQRCLHWSLLS

C16orf46

291

Q6P387
LSWIHPESQATITRC

MTMR1

291

Q13613
LPCVWNVQLSDHTLA

LARGE2

311

Q8N3Y3
HLCTNTWIQSTNVPI

ITPR3

391

Q14573
SENARLALCEHPQWT

NUP205

611

Q92621
SISIPLNSWSACHRD

ANKRD31

261

Q8N7Z5
HGVCSTWLNSLKPQD

NOS2

941

P35228
FLSPEQHACSWQLLL

FGFBP3

51

Q8TAT2
LTRHCQLLETPESWA

NUP98

1586

P52948
NCWSEAAPLLVHVSS

KLHL6

446

Q8WZ60
HNTKTTSWLDPRCLN

MAGI1

321

Q96QZ7
CHLQQVTDLPWTSVS

NCR2

236

O95944
LTSLTSDDNLWACLH

FLCN

241

Q8NFG4
LTGDCQKNIHLWTPT

GRWD1

231

Q9BQ67
HQSSWPTLHQCIRVL

INTS1

1666

Q8N201
DLRCQTHSSLPQISW

MFSD4A

41

Q8N468
TLCRNSVLWPHSHNQ

EURL

181

Q9NYK6
RHLCTNTWVHSTNIP

ITPR1

391

Q14643
TCTRSSQPWQAALLA

KLK14

46

Q9P0G3
QAHSLLCSFLPWSGI

NAA60

216

Q9H7X0
NHLWLLEGTPSLQSC

KIAA0319L

71

Q8IZA0
PLLCWDTTSSQHNLS

LRRC25

136

Q8N386
TEAHLLPLWLSTTNQ

EDEM3

491

Q9BZQ6
LDWSSHNVKCSNPQI

PLXNA2

846

O75051
NCITSLQLHPKGWAT

DCAF10

411

Q5QP82
NDTIRNSDSLWKPHC

FBXO48

66

Q5FWF7
QHCVWSSSLQQCLSP

MEGF8

2081

Q7Z7M0
WLTGALHLCSPLTSQ

PRCP

256

P42785
SHQCSLDWLLLGPAA

LRP3

96

O75074
WPRLQHLNLSSCSQL

LRRC29

151

Q8WV35
SLSQEHVESLCWLLS

NLRC5

1226

Q86WI3
CQLSQPEVAAHTWLL

OBSCN

4361

Q5VST9
ALCSNPIGQLHKTWA

RGL4

321

Q8IZJ4
LAQVWAQQIHSPLTC

FRG2C

191

A6NGY1
QSQLANLTVCHPAWS

GALR2

166

O43603
LCRLWTESLLHSNSS

ICE2

791

Q659A1
SLIANSWVLTAAHCI

CELA2B

61

P08218
HSSQWKDPALSQLIC

GADD45A

131

P24522
VQWNPCALLHSSTCS

POLQ

896

O75417
LSQKLCTLAWSAHPL

IL23A

36

Q9NPF7
CSGQHWSITNVLRSL

GALNT18

591

Q6P9A2
SECWAHNPASRLTAL

BMPR1A

501

P36894
LLCHSDNPSQLIWTS

HSD17B7

156

P56937
TLWCGLNHSLVLSQS

FBXO24

411

O75426
HCPNILTDRSLWLAS

FBXO41

666

Q8TF61
NTPHSTLSVNWSLLL

GLMP

86

Q8WWB7
WRSSENHPNLTCTAS

LY9

416

Q9HBG7
WALLLTICPSTQISH

IFRD2

306

Q12894
HPTTALCNIWDNTLL

HUS1B

246

Q8NHY5
GWTTISQLTQILSHC

IQCB1

76

Q15051
EASLSTAPSCHQQTW

GPR156

561

Q8NFN8
VELCSSDSLQWLPCH

IGFN1

881

Q86VF2
DLENHNSQLNWCSSP

EPS15

501

P42566
NSQLNWCSSPHSILV

EPS15

506

P42566
PDWLCHSSSNTAEIQ

CCDC168

6876

Q8NDH2
PIHISWLSLSRVNCS

CDKN3

26

Q16667
LLWQTSHSCLVFQPV

DHDDS

216

Q86SQ9
SHRCWAPLLDNSTAQ

SLC22A12

46

Q96S37
NLLWLALACSPVHTT

CHID1

6

Q9BWS9
SLTCHSISPQMWQLL

IPO8

661

O15397
ACWSPHTLLQSLDQL

RPUSD1

236

Q9UJJ7
LGWDSVQLSACHLLT

TAF3

21

Q5VWG9
SLLNLSIWHPNQSTT

RGSL1

156

A5PLK6
QWAIHPTFNLKSLSC

RNF135

256

Q8IUD6
SLLSPQWVLTAAHCF

TPSG1

66

Q9NRR2
LTCINASKPHWSSQE

SEZ6L

431

Q9BYH1
SQVNSLPAEWCEALH

SH3D19

656

Q5HYK7
SEQQPSWTDDLPLCH

TAB1

11

Q15750
SHRCWVPLLDNDTVS

SLC22A24

46

Q8N4F4
SHLLGPQSCWSSQKE

PPM1J

211

Q5JR12
RPTAEICLSHSWLQQ

STK17B

281

O94768
RATLIISPSSICHQW

SHPRH

716

Q149N8
ISPSSICHQWVDEIN

SHPRH

721

Q149N8
QSSCHVLWAPADINL

WRN

861

Q14191
NISSGHCILTWSISP

IL9R

156

Q01113
SDTQASITLNLPNCW

SLC36A3

311

Q495N2
LPTSHLDLACSLLWN

SREBF1

616

P36956
LLHITTCSFVAPWNS

TIMP1

116

P01033
LDWLCHLLTSDASSP

RNF213

641

Q63HN8
LTNHLSIWFATCLSI

TAS2R7

91

Q9NYW3
DIQPWLHSGSNSLLS

ZWILCH

381

Q9H900
HQCGASLISNTWLLT

TMPRSS11F

231

Q6ZWK6
HSNKPAQSDNLTIWC

CD96

341

P40200
LPHSSILRTWLSKCQ

THAP9

236

Q9H5L6
LALTSNSSWVQCPSH

TPP2

571

P29144
LWLLNNLTANSPSFC

TMCO6

361

Q96DC7
SLLTANEHWTPCILN

VPS13C

226

Q709C8
QLVNLTCLVWTTHPA

SIGLEC1

1101

Q9BZZ2
LCTSLPVWLENHTAL

GART

321

P22102
LSPETKHCILSWLGN

UBE4A

391

Q14139
SLLHPKSTDIWQGCL

XKR5

316

Q6UX68
QDLHATIQNWPSSSC

ZYG11A

646

Q6WRX3
SLFPHANEWLKNCTT

TERB1

201

Q8NA31
SWLLLGSLTHNAVCP

UNC79

2416

Q9P2D8
SLQTRTSWSAHQPCL

KCNH8

921

Q96L42
NVTWNSLAIPDTHCS

NALCN

216

Q8IZF0
LLRAHCQTSGWSLTE

MMUT

346

P22033