Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionscavenger receptor activity

SCARF1 STAB2 DMBT1

2.44e-0527423GO:0005044
GeneOntologyMolecularFunctionextracellular matrix structural constituent

LAMB2 HSPG2 THBS3 DMBT1

6.44e-04188424GO:0005201
GeneOntologyMolecularFunctionlow-density lipoprotein particle binding

SCARF1 STAB2

6.47e-0418422GO:0030169
GeneOntologyMolecularFunctioncargo receptor activity

SCARF1 STAB2 DMBT1

7.58e-0485423GO:0038024
GeneOntologyMolecularFunctioncalcium ion binding

HSPG2 THBS3 STAB2 MEGF8 ZZEF1 NOTCH4 MASP2

8.71e-04749427GO:0005509
GeneOntologyMolecularFunctionzinc ion transmembrane transporter activity

SLC39A10 SLC30A2

1.16e-0324422GO:0005385
GeneOntologyCellularComponentcollagen-containing extracellular matrix

LAMB2 HRG HSPG2 LAMB4 THBS3 DMBT1 RELL2

9.45e-05530437GO:0062023
GeneOntologyCellularComponentbasement membrane

LAMB2 HSPG2 LAMB4 RELL2

1.14e-04122434GO:0005604
GeneOntologyCellularComponentextracellular matrix

LAMB2 HRG HSPG2 LAMB4 THBS3 DMBT1 RELL2

3.50e-04656437GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

LAMB2 HRG HSPG2 LAMB4 THBS3 DMBT1 RELL2

3.56e-04658437GO:0030312
GeneOntologyCellularComponentzymogen granule membrane

DMBT1 SLC30A2

7.67e-0420432GO:0042589
GeneOntologyCellularComponentzymogen granule

DMBT1 SLC30A2

1.97e-0332432GO:0042588
MousePhenoabnormal sternum morphology

SEMA3A HSPG2 OSBP HOXD3 MEGF8 SLC30A2

2.54e-05255336MP:0000157
MousePhenoabnormal ophthalmic nerve morphology

SEMA3A MEGF8

3.23e-054332MP:0009798
MousePhenoabnormal pectoral girdle bone morphology

SEMA3A HSPG2 OSBP HOXD3 MEGF8 SLC30A2

6.43e-05301336MP:0004508
DomainLaminin_EGF

SCARF1 LAMB2 HSPG2 LAMB4 STAB2 MEGF8

2.33e-1038426IPR002049
DomainEGF_1

SCARF1 LAMB2 HSPG2 LAMB4 THBS3 STAB2 MEGF8 NOTCH4 MASP2

4.31e-09255429PS00022
DomainEGF-like_CS

SCARF1 LAMB2 HSPG2 LAMB4 THBS3 STAB2 MEGF8 NOTCH4 MASP2

5.28e-09261429IPR013032
DomainEGF_2

SCARF1 LAMB2 HSPG2 LAMB4 THBS3 STAB2 MEGF8 NOTCH4 MASP2

6.03e-09265429PS01186
DomainEGF_LAM_2

LAMB2 HSPG2 LAMB4 STAB2 MEGF8

6.15e-0930425PS50027
DomainEGF_LAM_1

LAMB2 HSPG2 LAMB4 STAB2 MEGF8

6.15e-0930425PS01248
DomainLaminin_EGF

SCARF1 LAMB2 HSPG2 LAMB4 MEGF8

1.39e-0835425PF00053
DomainEGF_Lam

LAMB2 HSPG2 LAMB4 STAB2 MEGF8

1.39e-0835425SM00180
DomainEGF

SCARF1 LAMB2 HSPG2 THBS3 STAB2 MEGF8 NOTCH4 MASP2

4.55e-08235428SM00181
DomainGrowth_fac_rcpt_

SCARF1 LAMB2 HSPG2 THBS3 STAB2 MEGF8 NOTCH4

5.23e-08156427IPR009030
DomainEGF-like_dom

SCARF1 LAMB2 HSPG2 THBS3 STAB2 MEGF8 NOTCH4 MASP2

7.12e-08249428IPR000742
DomainEGF_CA

HSPG2 THBS3 STAB2 MEGF8 NOTCH4 MASP2

2.97e-07122426SM00179
DomainEGF-like_Ca-bd_dom

HSPG2 THBS3 STAB2 MEGF8 NOTCH4 MASP2

3.27e-07124426IPR001881
DomainEGF_3

SCARF1 HSPG2 THBS3 STAB2 MEGF8 NOTCH4 MASP2

8.47e-07235427PS50026
Domain-

DMBT1 MEGF8 ZZEF1 MASP2

5.53e-06524242.60.120.290
DomainCUB_dom

DMBT1 MEGF8 ZZEF1 MASP2

8.00e-0657424IPR000859
DomainLAMININ_IVB

LAMB2 LAMB4

1.48e-053422PS51116
DomainLaminin_IV_B

LAMB2 LAMB4

1.48e-053422IPR013015
DomainEGF_CA

THBS3 MEGF8 NOTCH4 MASP2

4.10e-0586424PF07645
DomainBEX

BEX2 BEX5

4.92e-055422IPR007623
DomainEGF_Ca-bd_CS

THBS3 MEGF8 NOTCH4 MASP2

6.58e-0597424IPR018097
DomainEGF_CA

THBS3 MEGF8 NOTCH4 MASP2

7.12e-0599424PS01187
DomainCUB

DMBT1 MEGF8 MASP2

1.81e-0449423PF00431
DomainCUB

DMBT1 MEGF8 MASP2

1.93e-0450423SM00042
DomainCUB

DMBT1 MEGF8 MASP2

2.29e-0453423PS01180
DomainEGF_3

STAB2 MEGF8

3.21e-0412422PF12947
DomainEGF_dom

STAB2 MEGF8

3.21e-0412422IPR024731
DomainBEX

BEX2 BEX5

4.42e-0414422PF04538
DomainTF_A-like/BEX

BEX2 BEX5

4.42e-0414422IPR021156
DomainLAMININ_NTER

LAMB2 LAMB4

5.81e-0416422PS51117
DomainLaminin_N

LAMB2 LAMB4

5.81e-0416422PF00055
DomainLaminin_N

LAMB2 LAMB4

5.81e-0416422IPR008211
DomainLamNT

LAMB2 LAMB4

5.81e-0416422SM00136
DomainASX_HYDROXYL

MEGF8 NOTCH4 MASP2

1.47e-03100423PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

MEGF8 NOTCH4 MASP2

1.74e-03106423IPR000152
DomainEGF

HSPG2 STAB2 NOTCH4

2.84e-03126423PF00008
DomainPSI

SEMA3A MEGF8

4.40e-0344422IPR016201
DomainPSI

SEMA3A MEGF8

4.80e-0346422SM00423
DomainLaminin_G

HSPG2 THBS3

7.54e-0358422IPR001791
DomainEGF_extracell

SCARF1 STAB2

8.05e-0360422IPR013111
DomainEGF_2

SCARF1 STAB2

8.05e-0360422PF07974
PathwayKEGG_ECM_RECEPTOR_INTERACTION

LAMB2 HSPG2 LAMB4 THBS3

1.85e-0584274M7098
Pubmed

Matrilysin/MMP-7 Cleavage of Perlecan/HSPG2 Complexed with Semaphorin 3A Supports FAK-Mediated Stromal Invasion by Prostate Cancer Cells.

SEMA3A HSPG2

4.48e-06343229740048
Pubmed

A forward genetic screen in mice identifies Sema3A(K108N), which binds to neuropilin-1 but cannot signal.

SEMA3A MEGF8

4.48e-06343220410128
Pubmed

Sulfated polysaccharides identified as inducers of neuropilin-1 internalization and functional inhibition of VEGF165 and semaphorin3A.

SCARF1 SEMA3A

8.94e-06443218272814
Pubmed

The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1.

LAMB2 HSPG2

1.49e-0554327670489
Pubmed

Characterization of the Bex gene family in humans, mice, and rats.

BEX2 BEX5

1.49e-05543215958283
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

LAMB2 HRG HSPG2 DMBT1

6.56e-0517543428071719
Pubmed

Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.

LAMB2 HSPG2

1.15e-041343212682087
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

LAMB2 HSPG2 RELL2

1.30e-047943318757743
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

FRS3 LAMB2 THBS3 DMBT1

1.33e-0421043416537572
Pubmed

The transcription factors Grainyhead-like 2 and NK2-homeobox 1 form a regulatory loop that coordinates lung epithelial cell morphogenesis and differentiation.

SEMA3A BEX2

1.35e-041443222955271
Pubmed

Basement membrane composition in the early mouse embryo day 7.

LAMB2 HSPG2

1.55e-041543215895400
Pubmed

Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.

LAMB2 HSPG2

1.77e-041643217948866
Pubmed

FGFR2b signalling restricts lineage-flexible alveolar progenitors during mouse lung development and converges in mature alveolar type 2 cells.

ABCA3 BEX2

2.26e-041843236445537
Pubmed

Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.

LAMB2 LAMB4

2.26e-041843211311202
Pubmed

Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21.

DMBT1 DISP1

3.40e-042243226631746
Pubmed

Loss of semaphorin-neuropilin-1 signaling causes dysmorphic vascularization reminiscent of alveolar capillary dysplasia.

SEMA3A ABCA3

4.05e-042443223063659
Pubmed

Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events.

BEX2 BEX5

4.05e-042443216221301
Pubmed

An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders.

DLGAP2 METTL17 TRIM59 RNF111 BEX5

4.19e-0451443529892012
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

LAMB2 HSPG2 MEGF8

4.26e-0411843321078624
Pubmed

Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction.

LAMB2 HSPG2 DLGAP2

5.77e-0413143328634551
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

LAMB2 HSPG2

5.93e-042943222613833
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

SEMA3A LAMB2 HSPG2 THBS3 SLC39A10 MEGF8 ZZEF1

6.25e-04120143735696571
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

LAMB2 HRG HSPG2

6.30e-0413543328675934
Pubmed

Lung epithelial branching program antagonizes alveolar differentiation.

HSPG2 ABCA3

7.69e-043343224058167
Pubmed

Functional proteomics mapping of a human signaling pathway.

LAMB2 HSPG2 ZZEF1 ZNF341 RNF111

7.87e-0459143515231748
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

LAMB2 HRG HSPG2

7.91e-0414643327068509
Pubmed

Transcriptional analysis of cleft palate in TGFβ3 mutant mice.

KCP HSPG2

8.66e-043543232913205
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

LAMB2 HRG HSPG2

9.05e-0415343325037231
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

LAMB2 HSPG2 DMBT1

1.17e-0316743322159717
GeneFamilyBrain expressed X-linked family

BEX2 BEX5

2.65e-0553021217
GeneFamilyLaminin subunits

LAMB2 LAMB4

1.74e-0412302626
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

SCARF1 STAB2

9.10e-04273021253
CoexpressionNABA_MATRISOME

SEMA3A KCP LAMB2 HRG HSPG2 LAMB4 THBS3 DMBT1 MEGF8 IL17C MASP2

5.70e-0710264311M5889
CoexpressionNABA_MATRISOME

SEMA3A KCP LAMB2 HRG HSPG2 THBS3 DMBT1 MEGF8 IL17C MASP2

4.08e-0610084310MM17056
CoexpressionNABA_CORE_MATRISOME

KCP LAMB2 HSPG2 LAMB4 THBS3 DMBT1

5.56e-06275436M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

KCP LAMB2 LAMB4 THBS3 DMBT1

1.70e-05196435M3008
CoexpressionGSE2405_S_AUREUS_VS_A_PHAGOCYTOPHILUM_NEUTROPHIL_DN

APBA3 ABCA3 ZNF319 ZZEF1 ZNF341

1.87e-05200435M6208
CoexpressionNABA_BASEMENT_MEMBRANES

LAMB2 HSPG2 LAMB4

3.89e-0540433M5887
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_INTERMEDIATE_LYMPHATIC_ENDO_CELL

SEMA3A OSBP THBS3 ABCA3 STAB2 HOXD3

4.73e-05402436M45754
CoexpressionNABA_CORE_MATRISOME

KCP LAMB2 HSPG2 THBS3 DMBT1

7.81e-05270435MM17057
CoexpressionZHANG_GATA6_TARGETS_DN

SEMA3A THBS3 ABCA3

1.52e-0463433M1778
CoexpressionZHANG_GATA6_TARGETS_DN

SEMA3A THBS3 ABCA3

1.67e-0465433MM1226
ToppCellEndothelial-B-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

SEMA3A DLGAP2 STAB2 HOXD3 LRATD1

5.87e-071684354977c3837fbb1f36c89fddd5764e37290ac25ad8
ToppCellEndothelial-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

SEMA3A DLGAP2 STAB2 HOXD3 LRATD1

6.04e-0716943595c617143e1fbdd1d55a93ffdcc210e0be37cf2f
ToppCellE12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SCARF1 HSPG2 MBD5 ZNF365 FAM221B

6.59e-071724353b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D231|Adult / Lineage, Cell type, age group and donor

SEMA3A DLGAP2 STAB2 HOXD3 LRATD1

7.81e-07178435c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCellCOVID-19-Heart-Lymph_EC|Heart / Disease (COVID-19 only), tissue and cell type

SEMA3A DLGAP2 STAB2 HOXD3 LRATD1

8.03e-07179435411620201a860716a8773b92f50f7b94ef34a586
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)-|367C / Donor, Lineage, Cell class and subclass (all cells)

SEMA3A DLGAP2 STAB2 HOXD3 LRATD1

8.48e-07181435b244ecaa442bbef51289d8ec574ef08fa9e96318
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)|367C / Donor, Lineage, Cell class and subclass (all cells)

SEMA3A DLGAP2 STAB2 HOXD3 LRATD1

8.48e-07181435dd79de8098edb385a0f85d0e9621503cdf76ec43
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 SEMA3A LAMB2 DLGAP2 STAB2

9.19e-07184435453295362888c9a59d0e73c7a5b15914c50ff591
ToppCellEndothelial-endothelial_cell_of_lymph_vessel|World / Lineage, Cell type, age group and donor

SEMA3A DLGAP2 STAB2 HOXD3 LRATD1

1.02e-0618843580910dcbb51990f2baed240f319456c0d3fa2065
ToppCellEndothelial-B|World / lung cells shred on cell class, cell subclass, sample id

SEMA3A DLGAP2 STAB2 HOXD3 LRATD1

1.02e-061884355959a88728812a5f4cbfa54eddc7a73ccbaa2f68
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

SEMA3A DLGAP2 STAB2 HOXD3 LRATD1

1.02e-06188435c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel|Adult / Lineage, Cell type, age group and donor

SEMA3A DLGAP2 STAB2 HOXD3 LRATD1

1.08e-0619043591bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCellCOPD-Endothelial-Lymphatic|COPD / Disease state, Lineage and Cell class

SEMA3A HSPG2 DLGAP2 HOXD3 LRATD1

1.16e-0619343518bcf08068a236c4575c7a07181ac893dfdcbeeb
ToppCellIPF-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

SEMA3A DLGAP2 STAB2 HOXD3 LRATD1

1.22e-06195435de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCellChildren_(3_yrs)-Endothelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

SEMA3A DLGAP2 HOXD3 NOTCH4 LRATD1

1.22e-06195435094cf6591daa5ffad36e44122b6f524a3a34c2fd
ToppCelldistal-Endothelial-Lymphatic-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SEMA3A DLGAP2 STAB2 HOXD3 LRATD1

1.22e-06195435f45c1349932ee7eb419cced8a4fdedae3610953f
ToppCelldistal-Endothelial-Lymphatic|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SEMA3A DLGAP2 STAB2 HOXD3 LRATD1

1.25e-061964353e8a20e1d163dcbd3bbd99fe179d54af02298af0
ToppCellEndothelial|World / Lineage, Cell type, age group and donor

SEMA3A STAB2 HOXD3 NOTCH4 LRATD1

1.25e-0619643596c6d78482a130ce4e29f6629972a06d10d7530e
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

FRS3 ABCA3 STAB2 MYO15A SLC30A2

1.29e-061974356b6504c47c309bac4f790e2f372d454bbdea49e8
ToppCelldistal-Endothelial-Lymphatic-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SEMA3A DLGAP2 STAB2 HOXD3 LRATD1

1.29e-061974358f2e19409ebe9a490d5a245fa82c765ed6d77c3e
ToppCellTracheal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SCARF1 SEMA3A DLGAP2 STAB2 HOXD3

1.32e-06198435306e28d31fd587409a12dcccc6b2abd7dc9c2e0a
ToppCellTracheal-10x5prime-Endothelial-Endothelia_lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SCARF1 SEMA3A DLGAP2 STAB2 HOXD3

1.32e-0619843505429f18e1d74880c1835568c86177f661b3477a
ToppCellCOVID-19-kidney-Lymphatic_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

SEMA3A DLGAP2 STAB2 HOXD3

1.26e-05148434f777aa1674e898e2594b2b7c029d3d05dda04df9
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SCARF1 SEMA3A TRIM59 LRATD1

1.71e-05160434636127753e3a22831f39d4c8170df40901e4329d
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SCARF1 SEMA3A TRIM59 LRATD1

1.71e-05160434cb8d0dc1a6c69c7a85c5fdd8f0f6cca1b73dfc63
ToppCellPND14-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FRS3 SEMA3A HOXD3 RELL2

2.21e-05171434686f95892c3909973c66c9a27159a070a068f175
ToppCellPND14-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FRS3 SEMA3A HOXD3 RELL2

2.21e-05171434f7ba03e7bdb687f93782c936c7b3374cc5b3b77c
ToppCellPND14-Endothelial-Endothelial_lymphatic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FRS3 SEMA3A HOXD3 RELL2

2.21e-05171434d0ac50071a3854d02113c455fcc940a6ec59bbb9
ToppCellPND14-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FRS3 SEMA3A HOXD3 RELL2

2.21e-05171434fbf8e9db00573adcada4b25730e191417b7c9999
ToppCellEndothelial-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

SEMA3A DLGAP2 STAB2 LRATD1

2.27e-05172434d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D122|Adult / Lineage, Cell type, age group and donor

SEMA3A DLGAP2 HOXD3 LRATD1

2.32e-05173434dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCellEndothelial-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

SEMA3A DLGAP2 STAB2 LRATD1

2.32e-05173434a81992965137195d20fc498f750975303961a828
ToppCell(6)_Endothelial_cells-(6)_Endothelial-E|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

DISP1 NOTCH4 LRATD1 BEX5

2.37e-051744344a1b67ce5ea353b3f81f59fa57da07668146afca
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-ILC|Multiple_Sclerosis / Disease, Lineage and Cell Type

FRS3 ZNF319 ZNF365 FAM221B

2.37e-051744347c50bf9da37711266cc077eef4e54b58463f1d37
ToppCellmetastatic_Lymph_Node-Endothelial_cells-Lymphatic_ECs|metastatic_Lymph_Node / Location, Cell class and cell subclass

SEMA3A HSPG2 DLGAP2 STAB2

2.37e-05174434d551bc29afef071adf4c9bb80345352ec33441d8
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

SEMA3A DLGAP2 STAB2 HOXD3

2.48e-05176434c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

SEMA3A DLGAP2 STAB2 HOXD3

2.48e-0517643498c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCellmetastatic_Lymph_Node-Endothelial_cells|metastatic_Lymph_Node / Location, Cell class and cell subclass

SEMA3A HSPG2 DLGAP2 STAB2

2.53e-0517743471bf5d4bc67bda37a0499e5ec01af7dd5254041d
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCA3 BEX2 SLC30A2 TRIM59

2.53e-05177434a68c3688f12aee22f3cb4049c4bccacbacb0fae6
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCARF1 HSPG2 HOXD3 NOTCH4

2.53e-0517743412f8627124acbf436e75681ff1ce429ff5e3f256
ToppCelltumor_Lung-Endothelial_cells-EPCs|tumor_Lung / Location, Cell class and cell subclass

HSPG2 LAMB4 STAB2 NOTCH4

2.53e-05177434f8b152c09d56a97e8c0482fb1a3964c05f9dc8c5
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCARF1 HSPG2 HOXD3 NOTCH4

2.53e-05177434fdf2af00fc971f0cd3915e1416e4a256458d6ea8
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 SEMA3A STAB2 HOXD3

2.83e-051824340cde2775bdaaa2172499925bd59b0ac2d545eb27
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 SEMA3A STAB2 HOXD3

2.83e-051824342cc434e46985c66fc36de05344a67aa96d90abc9
ToppCelltumor_Lymph_Node_/_Brain-Endothelial_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

SCARF1 HSPG2 LAMB4 NOTCH4

2.83e-05182434d7cce5dd7046f06bf40f00c9dbfa610722b03333
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 SEMA3A LAMB2 STAB2

2.83e-05182434fd786c88826ad3d5cc5c3d80f8e392d6be1b5267
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 SEMA3A STAB2 HOXD3

2.83e-051824343e7457b2a70b45735fb75d6617b7f34cef28758e
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SEMA3A LAMB2 STAB2 HOXD3

2.89e-051834344d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SEMA3A DLGAP2 STAB2 HOXD3

2.89e-05183434bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCell(6)_Endothelial-F_(Lymphatics)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

SEMA3A STAB2 HOXD3 LRATD1

2.95e-0518443403ea613e00b45c81b752c14505a0538d698f551e
ToppCellPCW_13-14-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SCARF1 DLGAP2 STAB2 HOXD3

3.01e-051854343be9e05b929ac4d956b1d53284072f668a6c1959
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SEMA3A DLGAP2 STAB2 HOXD3

3.01e-05185434f9f48251bc33eb6bf2cff580d1a3207d21450aa0
ToppCellCOVID-19-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

SEMA3A DLGAP2 STAB2 HOXD3

3.01e-0518543436ce23893915f5c380cca39b2c33a516edf31c3a
ToppCellCOVID-19-Neuronal_cells-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

SEMA3A DLGAP2 STAB2 HOXD3

3.01e-051854344a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCellEndoth-Lymph|World / shred by cell class for parenchyma

SEMA3A DLGAP2 STAB2 LRATD1

3.01e-0518543497a6c4cd00684d4085d36ef32f7dbb99563ed357
ToppCellPCW_13-14-Endothelial-Endothelial_mature-lymphatic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SCARF1 DLGAP2 STAB2 HOXD3

3.01e-05185434c3dd64a726cb8a1fe048683c266b7532a714a52e
ToppCellPCW_05-06-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SCARF1 STAB2 HOXD3 NOTCH4

3.08e-05186434f51c76b1c3c6c49e0ebc9a913d8413e0b6a04d80
ToppCell343B-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DISP1 NOTCH4 LRATD1 BEX5

3.08e-05186434080e56113b89138277a2bd2eabddfa6cd1a18b61
ToppCellPCW_05-06-Endothelial-Endothelial_mature-lymphatic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SCARF1 STAB2 HOXD3 NOTCH4

3.08e-0518643486b218a400f9c64f92b050f00b49f09647b17437
ToppCell343B-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DISP1 NOTCH4 LRATD1 BEX5

3.08e-05186434dae6a98963c78bf7518ebab8dc02f173c3b0f7f7
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D175|Adult / Lineage, Cell type, age group and donor

SEMA3A DLGAP2 STAB2 HOXD3

3.14e-051874341e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCelltumor_Lymph_Node_/_Brain-Endothelial_cells-Tumor_ECs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

SCARF1 HSPG2 LAMB4 NOTCH4

3.14e-05187434be5f8c5802b0fa8cc1e274fdf06b13eb8ceb8ad4
ToppCell390C-Endothelial_cells-Endothelial-F_(Lymphatics)-|390C / Donor, Lineage, Cell class and subclass (all cells)

SEMA3A DLGAP2 STAB2 LRATD1

3.21e-051884341f40b959777d18ad88d239df8cca304f062ba04c
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SEMA3A DLGAP2 STAB2 HOXD3

3.21e-051884342db80767903703e7e0a1a37c598f7877a909ee94
ToppCell390C-Endothelial_cells-Endothelial-F_(Lymphatics)|390C / Donor, Lineage, Cell class and subclass (all cells)

SEMA3A DLGAP2 STAB2 LRATD1

3.21e-05188434aa69e3f44d506f5ef358a3374ac5160d847c858f
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SEMA3A DLGAP2 HOXD3 LRATD1

3.21e-05188434aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SEMA3A DLGAP2 STAB2 HOXD3

3.27e-051894340d18ea72bd58d32a8ab9a61cf97f5786642f804b
ToppCellAT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

SCARF1 LAMB2 ABCA3 DMBT1

3.27e-051894342d32f09efa982ae458568f6b1cd06bb5078d42a3
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SEMA3A DLGAP2 STAB2 HOXD3

3.27e-0518943455a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCellCOVID-19-lung-Lymphatic_EC|lung / Disease (COVID-19 only), tissue and cell type

SEMA3A DLGAP2 STAB2 HOXD3

3.27e-05189434c8db9aaf54ea3cc96c4a2f777c3389e0f31f67f3
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 HSPG2 STAB2 NOTCH4

3.27e-051894341d660bceee449aebf12fc9af4c74af246837b27a
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCARF1 HSPG2 STAB2 NOTCH4

3.27e-05189434a34f008dfcee4012977bbc5b60de6f0329ca2f65
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 SEMA3A STAB2 HOXD3

3.34e-05190434a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA3A LAMB2 HSPG2 STAB2

3.34e-05190434a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCellnormal_Lung-Endothelial_cells-Lymphatic_ECs|normal_Lung / Location, Cell class and cell subclass

SEMA3A STAB2 HOXD3 LRATD1

3.34e-051904342185db6007404a2b22325f91460dd17635be9bba
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SEMA3A DLGAP2 HOXD3 LRATD1

3.34e-051904346e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 SEMA3A STAB2 HOXD3

3.34e-051904340bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCell21-Trachea-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

SCARF1 HSPG2 STAB2 NOTCH4

3.34e-05190434bce09634acbc2cfd53666328e8aed8bf8835f845
ToppCellIPF-Endothelial-Lymphatic|World / Disease state, Lineage and Cell class

SEMA3A DLGAP2 HOXD3 LRATD1

3.34e-05190434ac029e73da5995221c9b9af551d85e4b835e21d6
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA3A LAMB2 HSPG2 STAB2

3.34e-0519043457c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA3A LAMB2 HSPG2 STAB2

3.34e-05190434f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCell21-Trachea-Endothelial-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

SCARF1 HSPG2 STAB2 NOTCH4

3.34e-0519043408437396a98ca9526f69c3a74bbf2929f3c68b8e
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCARF1 SEMA3A STAB2 HOXD3

3.34e-0519043426e2237f65cb43723c5da853831b40df2982d6e4
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SEMA3A DLGAP2 STAB2 LRATD1

3.48e-051924345f4f44f15d3a2846981e68296643a4634930a211
ToppCellIPF-Endothelial-Lymphatic|IPF / Disease state, Lineage and Cell class

SEMA3A DLGAP2 HOXD3 LRATD1

3.48e-051924342496edd8f3a41146d418879de9ee2ccc7857431f
ToppCellControl-Endothelial-Lymphatic|World / Disease state, Lineage and Cell class

SEMA3A DLGAP2 HOXD3 LRATD1

3.48e-05192434f95fb188aa642f3d0618242a770e7c4b70544adb
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SEMA3A DLGAP2 STAB2 LRATD1

3.48e-051924345e709c0714e8eba27e03a6def0544256bedb3ced
ToppCellControl-Endothelial-Lymphatic|Control / Disease state, Lineage and Cell class

SEMA3A DLGAP2 HOXD3 LRATD1

3.55e-0519343464d19be73e5432d491436a01da5de5c926b615a9
ToppCell(6)_Endothelial-C_(Capillary_Aerocyte_)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

SCARF1 SEMA3A DISP1 NOTCH4

3.55e-05193434f7f2dc6aff02d096a282835094d26d12b3b73e61
ToppCellnucseq-Endothelial-Endothelial_Lymphatic-LEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SEMA3A DLGAP2 HOXD3 LRATD1

3.63e-05194434f772a9f9ef8635aeaeb8b022dbb94e9672b36ead
ToppCellnucseq-Endothelial-Endothelial_Lymphatic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SEMA3A DLGAP2 HOXD3 LRATD1

3.63e-051944345d2b3ed5374e2ab10c1c7eb3a03139fc95036a48
ToppCellnucseq-Endothelial-Endothelial_Lymphatic-LEC-LEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SEMA3A DLGAP2 HOXD3 LRATD1

3.63e-051944343b73f2d305a7566f7ab567e5f18c82cd3d80e32c
ToppCellControl-Endothelial|Control / Disease state, Lineage and Cell class

SEMA3A HOXD3 NOTCH4 LRATD1

3.63e-05194434485fe5538fabec457b9a51feb641f2a91cbf4e18
ToppCellcellseq-Endothelial-Endothelial_Lymphatic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SEMA3A STAB2 HOXD3 LRATD1

3.70e-05195434d8f01746c8f92532bd1a5c1b0bbb86208d64c3cd
ToppCelldistal-2-Endothelial-Lymphatic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SEMA3A DLGAP2 STAB2 HOXD3

3.70e-051954348e0f67a67af3bc0b16f48a621f74540f136383b7
ToppCellcellseq-Endothelial-Endothelial_Lymphatic-LEC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SEMA3A STAB2 HOXD3 LRATD1

3.70e-05195434918b68a271a81202778714e10b09c5c724575b73
ToppCellcellseq-Endothelial-Endothelial_Lymphatic-LEC-LEC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SEMA3A STAB2 HOXD3 LRATD1

3.70e-051954348321531bb976e5005973b82f32177be88113abb3
ToppCellwk_08-11-Endothelial-Blood_vessel_endothelial-intermediate_cap|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SCARF1 HSPG2 NOTCH4 LRATD1

3.70e-05195434c0ea25ed1a849e6efff885e98013a4f1d5134758
ToppCell11.5-Distal-Endothelial|Distal / Age, Tissue, Lineage and Cell class

SCARF1 HSPG2 NOTCH4 LRATD1

3.70e-05195434efdede0f476883ffddd247fa7bc6449e7932613e
ToppCell11.5-Distal-Endothelial-Endothelial|Distal / Age, Tissue, Lineage and Cell class

SCARF1 HSPG2 NOTCH4 LRATD1

3.70e-051954341e9b52b201ab6c78f536609e2afe1d680c71a6e7
DrugLMWH

SCARF1 SEMA3A LAMB2 HRG HSPG2 LAMB4 THBS3 RNF111 MASP2

3.32e-06663439CID000000772
DiseaseFEV/FEC ratio

HSPG2 THBS3 ABCA3 DMBT1 ZNF319 MYO15A HOXD3

1.02e-031228397EFO_0004713
Diseasemultiple sclerosis symptom measurement

STAB2 ITPRID1

1.70e-0346392EFO_0803536
Diseasesex interaction measurement, inflammatory bowel disease

ZNF365 NOTCH4

2.42e-0355392EFO_0003767, EFO_0008343
Diseaseneurofilament light chain measurement

DLGAP2 MYO15A

2.59e-0357392EFO_0009178
DiseaseMalignant neoplasm of breast

SEMA3A HRG THBS3 ABCA3 ZNF365 NOTCH4

2.68e-031074396C0006142
Diseaseunipolar depression, bipolar disorder, schizophrenia, sex interaction measurement

LRATD1 RNF111

4.56e-0376392EFO_0003761, EFO_0008343, MONDO_0004985, MONDO_0005090

Protein segments in the cluster

PeptideGeneStartEntry
PSPGACHLHNGDLDH

APBA3

371

O96018
PHCNPEDISQLVHHH

ABCA3

766

Q99758
HTCGLAPPEDCEHLH

DLGAP2

96

Q9P1A6
VHPITHIHHCPCLQG

DISP1

1326

Q96F81
HCRPHHFHLSASNPD

HSPG2

1306

P98160
EHSQALHCHPEACGP

HSPG2

3881

P98160
PHGHHPHCHDFQDYG

HRG

401

P04196
IPAHCCICCHHHPHC

ITPRID1

801

Q6ZRS4
HTHPQSCHLGPGAAC

MYO15A

1171

Q9UKN7
GDPPHHDHHDEFCLM

BEX5

96

Q5H9J7
HEEHAATGPHPCRHH

FAM221B

336

A6H8Z2
HHDCNETQNCHDQPH

MEGF8

2186

Q7Z7M0
LHHTEGPHCAHCKPG

LAMB2

1011

P55268
CTPCPESPSRHHHHL

LRATD1

61

Q96KN4
CLAHHDPSLRGHPHS

IL17C

16

Q9P0M4
CAAQIPGNHHHGPCD

HOXD3

391

P31249
LCEQVSHHPPAAAHH

OSBP

516

P22059
CQGLCPSLHDPPHHN

FRS3

256

O43559
VSTDPPHHDHHDEFC

BEX2

111

Q9BXY8
PGEAPTCDHHCHNHL

MASP2

146

O00187
LDHPGHIHSSPCHER

MBD5

1216

Q9P267
SYDLGHHGCHPCHCH

LAMB4

806

A4D0S4
HHGCHPCHCHPQGSK

LAMB4

811

A4D0S4
SCPHNGWLSHNCGHH

DMBT1

811

Q9UGM3
CPHNGWLSHNCGHHE

DMBT1

1201

Q9UGM3
HCNHCHEEHDHGPEA

SLC39A10

21

Q9ULF5
PRHVHCHLCCPDGHM

METTL17

396

Q9H7H0
HHTVHLGSAAPCLHC

RELL2

121

Q8NC24
DGAAHCGPQAHLPHC

KCP

121

Q6ZWJ8
GDPLTHCSDLHHDNH

SEMA3A

561

Q14563
HRAPSCGFHHCHHGG

NOTCH4

1086

Q99466
CGFHHCHHGGLCLPS

NOTCH4

1091

Q99466
PHCRHGEACEPDTGH

SCARF1

311

Q14162
CSRLPHHGHHVAACQ

TTLL8

756

A6PVC2
EHHLQTATHNFPCPH

ZNF341

556

Q9BYN7
PHSVCNHPDLKAHFH

ZNF365

326

Q70YC5
PLHHQASACPHSHGN

RNF111

656

Q6ZNA4
HIHQQPPHSKCFEDH

SPATA31D1

481

Q6ZQQ2
HDPNTHHCLCGADAD

XRN2

221

Q9H0D6
CHPHAHCTYLGPNRH

STAB2

246

Q8WWQ8
PAHSPCHIHAHCLFE

THBS3

421

P49746
CGHDLAHLSSPHEHQ

ZNF319

81

Q9P2F9
QHCAESLGQPHCFHP

ZZEF1

1596

O43149
DHHHHGCCEPVYILE

ZNF800

11

Q2TB10
HRHPLDHDCSGEGHP

ZFAND2B

126

Q8WV99
VCGHCLTIGQHHGHP

TRIM59

116

Q8IWR1
FCNHHCHQHPPSHLT

nan

86

Q8TCH9
HHCHAQKGPDSHCDP

SLC30A2

51

Q9BRI3