Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	NAD(P)H oxidase H2O2-forming activity	FMO5 KMO	5.19e-04	12	57	2	GO:0016174
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	HNF1B ZNF266 EGR3 NFE2L1 NFIB NEUROD4 GLI2 ZNF780B GATA2 ZHX2 BHLHE40 ZIC1	5.36e-04	1412	57	12	GO:0000981
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	EGR3 NFE2L1 NFIB GLI2 ZNF780B GATA2 ZIC1	1.03e-03	560	57	7	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	EGR3 NFE2L1 NFIB GLI2 ZNF780B GATA2 ZIC1	1.10e-03	566	57	7	GO:0001216
GeneOntologyMolecularFunction	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	FMO5 KMO	1.47e-03	20	57	2	GO:0050664
GeneOntologyMolecularFunction	flavin adenine dinucleotide binding	DMGDH FMO5 KMO	2.46e-03	94	57	3	GO:0050660
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	HNF1B ZNF266 EGR3 NFE2L1 NFIB NEUROD4 GLI2 ZNF780B GATA2 BHLHE40 ZIC1	2.48e-03	1459	57	11	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	HNF1B EGR3 NFE2L1 NFIB NEUROD4 GLI2 ZNF780B GATA2 BHLHE40 ZIC1	2.51e-03	1244	57	10	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	HNF1B EGR3 NFE2L1 NFIB NEUROD4 GLI2 ZNF780B GATA2 BHLHE40 ZIC1	2.93e-03	1271	57	10	GO:0000987
GeneOntologyMolecularFunction	hydrolase activity, hydrolyzing O-glycosyl compounds	GALC SI NAGPA	3.19e-03	103	57	3	GO:0004553
GeneOntologyMolecularFunction	protein domain specific binding	DOCK3 RIPK1 NFE2L1 ZMYND8 GATA2 OCLN RRM1 BHLHE40	3.24e-03	875	57	8	GO:0019904
GeneOntologyBiologicalProcess	spinal cord development	MPST NFE2L1 GLI2 GATA2 ZIC1	2.11e-05	119	58	5	GO:0021510
GeneOntologyBiologicalProcess	sensory organ development	PTPRM NFIB NEUROD4 GLI2 CECR2 GATA2 FRS2 RRM1 ZHX2 ZIC1	3.25e-05	730	58	10	GO:0007423
GeneOntologyBiologicalProcess	neural precursor cell proliferation	FLNA NFIB NEUROD4 GATA2 FRS2 RRM1	4.83e-05	233	58	6	GO:0061351
MousePheno	abnormal cerebellum development	NFIB NEUROD4 GLI2 FRS2 ZIC1	1.68e-05	96	47	5	MP:0000854
MousePheno	abnormal hindbrain morphology	DOCK3 GALC NFIB NEUROD4 GLI2 CECR2 FRS2 OCLN ZIC1	2.85e-05	485	47	9	MP:0000841
MousePheno	abnormal cerebellar foliation	NFIB NEUROD4 GLI2 ZIC1	4.17e-05	58	47	4	MP:0000857
MousePheno	abnormal metencephalon morphology	DOCK3 GALC NFIB NEUROD4 GLI2 FRS2 OCLN ZIC1	6.98e-05	420	47	8	MP:0000847
MousePheno	abnormal cerebellum lobule morphology	NFIB NEUROD4 GLI2 ZIC1	8.26e-05	69	47	4	MP:0009964
MousePheno	abnormal hindbrain development	NFIB NEUROD4 GLI2 FRS2 ZIC1	2.15e-04	164	47	5	MP:0006108
MousePheno	abnormal pulmonary alveolar parenchyma morphology	COPA NFIB GLI2 LAMA3	2.32e-04	90	47	4	MP:0010901
MousePheno	abnormal cerebellum morphology	DOCK3 NFIB NEUROD4 GLI2 FRS2 OCLN ZIC1	2.95e-04	389	47	7	MP:0000849
MousePheno	small lung saccule	NFIB GLI2	3.06e-04	8	47	2	MP:0010827
Domain	FAD-dep_OxRdtase	DMGDH KMO	5.92e-04	12	57	2	IPR006076
Domain	DAO	DMGDH KMO	5.92e-04	12	57	2	PF01266
Domain	-	DMGDH FMO5 KMO	6.66e-04	56	57	3	3.50.50.60
Domain	FAD/NAD-binding_dom	DMGDH FMO5 KMO	7.02e-04	57	57	3	IPR023753
Pubmed	Pax3 synergizes with Gli2 and Zic1 in transactivating the Myf5 epaxial somite enhancer.	GLI2 ZIC1	8.19e-06	3	58	2	24036067
Pubmed	Effect of mutations in HNF-1alpha and HNF-1beta on the transcriptional regulation of human sucrase-isomaltase in Caco-2 cells.	HNF1B SI	8.19e-06	3	58	2	15522234
Pubmed	Decreased A-to-I RNA editing as a source of keratinocytes' dsRNA in psoriasis.	FLNA COPA	8.19e-06	3	58	2	29592874
Pubmed	Expression of Ripk1 and DAM genes correlates with severity and progression of Krabbe disease.	GALC RIPK1	8.19e-06	3	58	2	34172992
Pubmed	Cardiovascular defects in a mouse model of HOXA1 syndrome.	HNF1B ZIC1	1.64e-05	4	58	2	21940751
Pubmed	A census of human transcription factors: function, expression and evolution.	EGR3 NFE2L1 NFIB NEUROD4 GLI2 GATA2 ZHX2 BHLHE40 ZIC1	1.83e-05	908	58	9	19274049
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	FLNA COPA NFE2L1 ZMYND8 POMT1 PRRC2B	1.93e-05	332	58	6	37433992
Pubmed	Physical and functional interactions between Zic and Gli proteins.	GLI2 ZIC1	4.08e-05	6	58	2	11238441
Pubmed	The transcription factors GATA2 and microphthalmia-associated transcription factor regulate Hdc gene expression in mast cells and are required for IgE/mast cell-mediated anaphylaxis.	GATA2 BHLHE40	4.08e-05	6	58	2	29277702
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	DMGDH FLNA GTF3C2 RIPK1 NFIB FRS2 POMT1 RRM1 KMO ALG13	5.00e-05	1293	58	10	15342556
Pubmed	Sonic hedgehog regulates the growth and patterning of the cerebellum.	GLI2 ZIC1	5.71e-05	7	58	2	10375501
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	FAM171A1 PTPRM FRS2 GOLGA5 OCLN AGAP1	7.22e-05	421	58	6	36976175
Pubmed	Human transcription factor protein interaction networks.	BRIX1 HNF1B GTF3C2 COPA NFIB GLI2 ZMYND8 GATA2 ZHX2 PRRC2B	1.15e-04	1429	58	10	35140242
Pubmed	CD spectra show the relational style between Zic-, Gli-, Glis-zinc finger protein and DNA.	GLI2 ZIC1	1.22e-04	10	58	2	18298960
Pubmed	A role for Zic1 and Zic2 in Myf5 regulation and somite myogenesis.	GLI2 ZIC1	1.22e-04	10	58	2	21211521
Pubmed	Common variation contributes to the genetic architecture of social communication traits.	OR5V1 MYO1E	1.22e-04	10	58	2	24047820
Pubmed	The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog-driven medulloblastoma.	GLI2 ZIC1	1.49e-04	11	58	2	25150496
Pubmed	Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung.	GLI2 LAMA3	1.49e-04	11	58	2	12051813
Pubmed	Neuronal defects in the hindbrain of Hoxa1, Hoxb1 and Hoxb2 mutants reflect regulatory interactions among these Hox genes.	NEUROD4 GATA2	1.49e-04	11	58	2	14522873
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	FLNA GTF3C2 COPA ZMYND8 RRM1	2.33e-04	332	58	5	32786267
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	EGR3 NFIB GLI2 GATA2 BHLHE40 ZIC1	2.89e-04	544	58	6	28473536
Pubmed	Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development.	GLI2 LAMA3	3.23e-04	16	58	2	12533516
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	FLNA FMO5 ZMYND8 BEX4 ZIC1	3.51e-04	363	58	5	14691545
Pubmed	Mouse Fkbp8 activity is required to inhibit cell death and establish dorso-ventral patterning in the posterior neural tube.	NEUROD4 ZIC1	3.66e-04	17	58	2	18003640
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	MYO1E PTPRM FRS2 GOLGA5 OCLN AGAP1	3.68e-04	569	58	6	30639242
Pubmed	OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis.	RIPK1 ALG13	4.59e-04	19	58	2	23827681
Pubmed	Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche.	HNF1B GLI2	4.59e-04	19	58	2	34433966
Pubmed	Pericytes are required for blood-brain barrier integrity during embryogenesis.	OCLN ZIC1	4.59e-04	19	58	2	20944625
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	MPST GTF3C2 RIPK1 MYO1E RRM1	5.45e-04	400	58	5	35013556
Pubmed	T-Box transcription factor Tbx20 regulates a genetic program for cranial motor neuron cell body migration.	NEUROD4 GATA2	5.62e-04	21	58	2	17119020
Pubmed	EEF1D Promotes Glioma Proliferation, Migration, and Invasion through EMT and PI3K/Akt Pathway.	MYO1E PRRC2B	5.62e-04	21	58	2	33029523
Pubmed	Tcf/Lef repressors differentially regulate Shh-Gli target gene activation thresholds to generate progenitor patterning in the developing CNS.	GLI2 GATA2	6.18e-04	22	58	2	21775418
Pubmed	Genome-wide association study to identify single nucleotide polymorphisms (SNPs) associated with the development of erectile dysfunction in African-American men after radiotherapy for prostate cancer.	GLI2 LRP1B	6.76e-04	23	58	2	20932654
Pubmed	Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development.	GLI2 ZIC1	6.76e-04	23	58	2	21937600
Pubmed	Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity.	GATA2 ZIC1	7.37e-04	24	58	2	24335253
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CLK2 NFIB CDK13 GLI2 LAMA3 TMPRSS5 POMT1 ZHX2 AGAP1	7.56e-04	1489	58	9	28611215
Pubmed	Identification of novel Hoxa1 downstream targets regulating hindbrain, neural crest and inner ear development.	HNF1B ZIC1	8.00e-04	25	58	2	21784065
Pubmed	Multiple developmental programs are altered by loss of Zic1 and Zic4 to cause Dandy-Walker malformation cerebellar pathogenesis.	GLI2 ZIC1	8.00e-04	25	58	2	21307096
Pubmed	Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition.	NFIB BHLHE40	9.34e-04	27	58	2	27178982
Pubmed	Rhombomere-specific analysis reveals the repertoire of genetic cues expressed across the developing hindbrain.	GATA2 BHLHE40	9.34e-04	27	58	2	19208226
Pubmed	Global proteomics of Ubqln2-based murine models of ALS.	MPST FLNA RIPK1 OCLN	9.57e-04	261	58	4	33277362
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	FRS2 GOLGA5 OCLN PRRC2B	9.84e-04	263	58	4	34702444
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	HNF1B MYO1E NFIB GOLGA5 PRRC2B	9.91e-04	457	58	5	32344865
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	DMGDH PLBD1 ZNF266 ZMYND8 BHLHE40 PRRC2B AGAP1 ALG13	1.02e-03	1242	58	8	30973865
Pubmed	ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.	BRIX1 FLNA COPA MYO1E	1.06e-03	268	58	4	33024031
Pubmed	Direct and indirect requirements of Shh/Gli signaling in early pituitary development.	GLI2 GATA2	1.08e-03	29	58	2	20934421
Pubmed	Distinct effects of Hedgehog signaling on neuronal fate specification and cell cycle progression in the embryonic mouse retina.	NEUROD4 GLI2	1.08e-03	29	58	2	19474320
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	FAM171A1 RIPK1 COPA FRS2 OCLN RRM1	1.15e-03	708	58	6	39231216
Pubmed	Suppressor of fused is required to maintain the multipotency of neural progenitor cells in the retina.	NEUROD4 GLI2	1.15e-03	30	58	2	21451052
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	NFE2L1 NEUROD4 GLI2 ZMYND8 GATA2 BHLHE40	1.16e-03	709	58	6	22988430
Pubmed	Purification and identification of G protein-coupled receptor protein complexes under native conditions.	FLNA COPA	1.23e-03	31	58	2	17215244
Pubmed	Hepatic ribosomal protein S6 (Rps6) insufficiency results in failed bile duct development and loss of hepatocyte viability; a ribosomopathy-like phenotype that is partially p53-dependent.	HNF1B BEX4	1.23e-03	31	58	2	36656901
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DOCK3 COPA MYO1E ZMYND8 BEX4 LRP1B BHLHE40 AGAP1	1.26e-03	1285	58	8	35914814
Pubmed	The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.	BRIX1 FLNA GTF3C2 CDK13 ALG13	1.27e-03	483	58	5	36912080
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	BRIX1 GTF3C2 COPA NFIB CDK13 ZMYND8 GATA2 BHLHE40	1.32e-03	1294	58	8	30804502
Pubmed	A Noncanonical Role of Fructose-1, 6-Bisphosphatase 1 Is Essential for Inhibition of Notch1 in Breast Cancer.	FLNA COPA MYO1E PRRC2B	1.34e-03	286	58	4	32041737
Pubmed	Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.	RIPK1 CDK13 GOLGA5	1.45e-03	133	58	3	15144186
Pubmed	Landscape of the SOX2 protein-protein interactome.	FLNA COPA MYO1E	1.54e-03	136	58	3	21280222
Pubmed	Diversification of stem cell molecular repertoire by alternative splicing.	BRIX1 CLK2	1.57e-03	35	58	2	16183747
Pubmed	Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.	GTF3C2 COPA NEK11	1.64e-03	139	58	3	25476789
Interaction	SOX15 interactions	BRIX1 HNF1B NFIB ZHX2 BHLHE40	3.75e-05	141	54	5	int:SOX15
Interaction	ATXN1L interactions	HNF1B NFIB GATA2 PRRC2B ALG13	5.04e-05	150	54	5	int:ATXN1L
Interaction	GSE1 interactions	HNF1B NFIB ZMYND8 GATA2 ALG13	5.71e-05	154	54	5	int:GSE1
Interaction	TLE3 interactions	FLNA HNF1B NFIB GLI2 CECR2 GATA2 ALG13	6.20e-05	376	54	7	int:TLE3
Interaction	KDM2B interactions	HNF1B NFIB GLI2 GATA2 ALG13	7.05e-05	161	54	5	int:KDM2B
Interaction	BCL9 interactions	HNF1B NFIB GATA2 ALG13	8.31e-05	86	54	4	int:BCL9
Interaction	PRR12 interactions	HNF1B NFIB GATA2 ALG13	9.09e-05	88	54	4	int:PRR12
Interaction	ZNF608 interactions	HNF1B NFIB GATA2 ALG13	1.13e-04	93	54	4	int:ZNF608
Interaction	GPAT2 interactions	PLBD1 TMPRSS5 PPTC7	1.22e-04	36	54	3	int:GPAT2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 DOCK3 MYO1E LAMA3 OCLN LRP1B	1.61e-07	187	58	6	87b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 DOCK3 MYO1E LAMA3 OCLN LRP1B	1.61e-07	187	58	6	42a1267bfc27b4460b8409ada580a87c4385841c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 DOCK3 MYO1E LAMA3 OCLN LRP1B	1.61e-07	187	58	6	64afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 HNF1B CECR2 LAMA3 OCLN LRP1B	1.61e-07	187	58	6	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 HNF1B MYO1E LAMA3 OCLN NEK11	1.94e-07	193	58	6	f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 HNF1B MYO1E LAMA3 OCLN NEK11	1.94e-07	193	58	6	42df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAM171A1 NFE2L1 CYYR1 GATA2 TMPRSS5	1.86e-06	156	58	5	ff39712c7a2dc1b85c598d5105789aa291dea726
ToppCell	COPD-Myeloid-Mast\|World / Disease state, Lineage and Cell class	FMNL3 FAM171A1 GALC GATA2 AGAP1	3.95e-06	182	58	5	68a1e7b804f309bfd6c23d65fad20a9a962712ae
ToppCell	COVID-19-Endothelial_cells-Systemic_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	FAM171A1 MYO1E PTPRM NFIB CYYR1	4.28e-06	185	58	5	f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCell	COPD-Myeloid-Mast\|COPD / Disease state, Lineage and Cell class	FMNL3 FAM171A1 GALC GATA2 AGAP1	4.39e-06	186	58	5	def6f0f284acc2154738574c8c5d3d2a5ef1f208
ToppCell	COVID-19-lung-Artery_EC\|lung / Disease (COVID-19 only), tissue and cell type	FAM171A1 MYO1E PTPRM NFIB CYYR1	4.62e-06	188	58	5	eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PTPRM CECR2 LAMA3 OCLN BHLHE40	4.87e-06	190	58	5	8aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell	COVID-19-lung-Artery_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FAM171A1 MYO1E PTPRM CYYR1 BHLHE40	4.87e-06	190	58	5	07b675befcd1d0a9c90cb17b5d22323468325d51
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 FAM171A1 MYO1E GATA2 BHLHE40	5.12e-06	192	58	5	fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAM171A1 PTPRM NFIB CYYR1 GATA2	5.39e-06	194	58	5	71ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 HNF1B LAMA3 OCLN NEK11	5.39e-06	194	58	5	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	Lung_Parenchyma-Severe-Myeloid-Macrophage-Macrophages-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FAM171A1 PTPRM NFIB CYYR1 GATA2	6.25e-06	200	58	5	e6d36be0c4c569e27303bb4e4f34cd2187e9759d
ToppCell	Lung_Parenchyma-Control-Myeloid-Macrophage-Macrophages-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FAM171A1 PTPRM NFIB CYYR1 GATA2	6.25e-06	200	58	5	98f6a86fbbe5305c71dae91e7278de9813827935
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Macrophages\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	FAM171A1 PTPRM NFIB CYYR1 GATA2	6.25e-06	200	58	5	c0c51719cf81512c50bfcc2fed883c867e522d2a
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_only / Treatment groups by lineage, cell group, cell type	FAM171A1 PTPRM NFIB GATA2 OCLN	6.25e-06	200	58	5	b1fadb2b5e37e0f51e079d8409c2647eef68dc3b
ToppCell	Lung_Parenchyma-Severe-Myeloid-Macrophage\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	FAM171A1 PTPRM NFIB CYYR1 GATA2	6.25e-06	200	58	5	758840c31f2ddd7ccf7bf13252ebb48d33e89479
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FAM171A1 PTPRM NFIB GATA2 OCLN	6.25e-06	200	58	5	a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FAM171A1 PTPRM NFIB GATA2 OCLN	6.25e-06	200	58	5	89a6da2bdedc6b1ad0675c8753bf2b763a99af6a
ToppCell	Parenchyma_Control_(B.)-Endothelial-TX-Macrophages\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	FAM171A1 PTPRM NFIB CYYR1 GATA2	6.25e-06	200	58	5	d7b89a721988660d8010c804916f5d0ef2520ee2
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FAM171A1 PTPRM NFIB GATA2 OCLN	6.25e-06	200	58	5	b70b7adb7c187e6253c7f0bb4c1f09c85ef7142c
ToppCell	Lung_Parenchyma-Control-Myeloid-Macrophage-Macrophages\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	FAM171A1 PTPRM NFIB CYYR1 GATA2	6.25e-06	200	58	5	1ed1c673184f0c6aae04f90edbb1383b1c1f64d9
ToppCell	Lung_Parenchyma-Control-Myeloid-Macrophage\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	FAM171A1 PTPRM NFIB CYYR1 GATA2	6.25e-06	200	58	5	2a1ba87ca4adf351ef8fa2b3154b86a5407b8f2f
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FAM171A1 PTPRM NFIB GATA2 OCLN	6.25e-06	200	58	5	58a7ece7dfdf6c46f2a50cbcb580574dec14c748
ToppCell	LPS_IL1RA_TNF-Endothelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FAM171A1 PTPRM NFIB GATA2 OCLN	6.25e-06	200	58	5	d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCell	Control_saline-Endothelial-Endothelial-Vein\|Control_saline / Treatment groups by lineage, cell group, cell type	FAM171A1 NFE2L1 NFIB GATA2 LRP1B	6.25e-06	200	58	5	e5f876910bc8cb390d9b46a48d9b6d4d57235551
ToppCell	Lung_Parenchyma-Severe-Myeloid-Macrophage-Macrophages\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	FAM171A1 PTPRM NFIB CYYR1 GATA2	6.25e-06	200	58	5	c37fe06a94e5779c56e01389869bb432d3bbaebc
ToppCell	facs-Brain_Myeloid-Cortex-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA PLBD1 BHLHE40 KMO	4.85e-05	154	58	4	1e088b0d4a44267f46a9b643f46a1aba784686b1
ToppCell	PND03-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLBD1 CLK2 BHLHE40 KMO	5.10e-05	156	58	4	af47a4b17342bdb3cb62d7e2d52a81168e588629
ToppCell	facs-Lung-EPCAM-3m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLBD1 BCO2 BHLHE40 KMO	6.34e-05	165	58	4	2477b0f1a0ea26184cf3cc4a9ffcdfa825cbc615
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1E NEUROD4 CECR2 KMO	6.34e-05	165	58	4	22293c6b55f44636440cd737efb786ff5de3373d
ToppCell	nucseq-Immune-Hematopoietic-Granulocytic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GALC GATA2 LRP1B AGAP1	6.34e-05	165	58	4	37615622c736e43260c38016e7c9e565ac97a3e8
ToppCell	nucseq-Immune-Hematopoietic-Granulocytic-Mast/Basophil\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GALC GATA2 LRP1B AGAP1	6.34e-05	165	58	4	640bb71e74a61df2fcb01ceeabe4c493ef836b21
ToppCell	nucseq-Immune-Hematopoietic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GALC GATA2 LRP1B AGAP1	6.34e-05	165	58	4	f3df74b5763130c71c0a482a3a23f6b22acc2892
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAM171A1 CYYR1 LAMA3 RRM1	6.49e-05	166	58	4	8e2faca6a2e76a625de04d6098aa6f98911945c6
ToppCell	facs-Tongue-nan-3m-Epithelial-basal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYYR1 BEX4 OCLN PPTC7	6.80e-05	168	58	4	ca0c4a819f9047fc40d224f7656fec60f6fa05d8
ToppCell	368C-Myeloid-Mast_cell\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	GALC EGR3 GATA2 AGAP1	7.62e-05	173	58	4	8cffb4a37d30b6626188309b868ac4a62e91262f
ToppCell	368C-Myeloid-Mast_cell-\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	GALC EGR3 GATA2 AGAP1	7.62e-05	173	58	4	fb87ea74bf70aa83b458edf728c81857c8b8eb96
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D175\|Adult / Lineage, Cell type, age group and donor	FAM171A1 EGR3 CYYR1 LRP1B	7.96e-05	175	58	4	0a65ddfa8c2e8efb5b5338cf07661cb78157a23c
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-OMD+_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	TANC2 PTPRM GATA2 BHLHE40	8.14e-05	176	58	4	52af8f717dbd3b59eeb868b8b7b256a8f3e57d7a
ToppCell	Nasal_Brush-Epithelial-Basal_2\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	FLNA EGR3 CYYR1 LAMA3	8.14e-05	176	58	4	fc5787946f5a10056d326d070620575ae4081836
ToppCell	Nasal_Brush-Epithelial-Basal_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	FLNA EGR3 CYYR1 LAMA3	8.14e-05	176	58	4	5daaba0853afe7d20d4635169ccd4f96e735b938
ToppCell	ASK440-Immune-Mast_cell\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	EGR3 GATA2 BHLHE40 AGAP1	8.51e-05	178	58	4	dcefc4afca3a40d1bd44722e66bca6b45a6c6c55
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Proliferative_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	PTPRM EGR3 CYYR1 GATA2	8.69e-05	179	58	4	d24513a404c9b1d37dd47aa1cdb5713b64b88f89
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPST DMGDH HNF1B OCLN	9.27e-05	182	58	4	770ce9f3f4538d0181a0181543841bc964c68274
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 CECR2 LAMA3 LRP1B	9.27e-05	182	58	4	a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell	droplet-Heart-nan-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRM CECR2 CYYR1 GATA2	9.27e-05	182	58	4	81279877b920b5a1bc991a07d3031d6458700fe3
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPST DMGDH HNF1B OCLN	9.27e-05	182	58	4	77ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPST DMGDH HNF1B OCLN	9.27e-05	182	58	4	4921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCell	facs-Lung-nan-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 PTPRM LAMA3 OCLN	9.47e-05	183	58	4	12e876d6205af8aad74265c668b5e95b9e7487f3
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FAM171A1 CYYR1 GATA2 BHLHE40	9.47e-05	183	58	4	c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EGR3 RRM1 ZHX2 ALG13	9.67e-05	184	58	4	780d67f04fc795f614e077d8a5cf368542f6d99d
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TANC2 HNF1B CECR2 LAMA3	9.67e-05	184	58	4	ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-mast_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FMNL3 GALC GATA2 BHLHE40	9.87e-05	185	58	4	3fafb1d36c5f98a29d20a5ce5192c83d6f603514
ToppCell	(4)_Mast_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	GALC EGR3 GATA2 BHLHE40	9.87e-05	185	58	4	c91e1081e630a61c18f6af6d198bfcf296746852
ToppCell	(4)_Mast_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	GALC EGR3 GATA2 BHLHE40	9.87e-05	185	58	4	3dd5d2237ab50b13a41c12f85e1b79cd72ea567b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAM171A1 GATA2 LRP1B BHLHE40	1.01e-04	186	58	4	08632045d499e61dd96ff29a5a9a208afe58dc58
ToppCell	Adult-Endothelial-endothelial_cell_of_artery\|Adult / Lineage, Cell type, age group and donor	FAM171A1 EGR3 CYYR1 GATA2	1.01e-04	186	58	4	2d1c4ea2e401db89971582ee54618a8b0c81b8ac
ToppCell	COVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	FAM171A1 PTPRM NFIB CYYR1	1.03e-04	187	58	4	2d20193a6cacdfa4877457c97b0077408942186c
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	MYO1E PTPRM CYYR1 GATA2	1.03e-04	187	58	4	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	Control-Endothelial_cells-Arterial_endothelial_cells\|Control / group, cell type (main and fine annotations)	FAM171A1 PTPRM NFIB CYYR1	1.03e-04	187	58	4	81affaab3fe3e1daea45ada6445e906ddd33950e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK3 FAM171A1 CECR2 LRP1B	1.05e-04	188	58	4	2ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TANC2 HNF1B CECR2 LAMA3	1.05e-04	188	58	4	4bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DOCK3 HNF1B LAMA3 OCLN	1.05e-04	188	58	4	0d86044bc340e3efb90d0022dd299873639d831c
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DOCK3 HNF1B LAMA3 OCLN	1.05e-04	188	58	4	beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK3 FAM171A1 CECR2 LRP1B	1.07e-04	189	58	4	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	Control-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	FAM171A1 NFIB CYYR1 GATA2	1.07e-04	189	58	4	f83f7521e377ded1522639e9a35c98b3e2725bac
ToppCell	ASK440-Immune-Mast_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	EGR3 GATA2 BHLHE40 AGAP1	1.07e-04	189	58	4	72a19b20cb0f7283afe5f85d62a21cff69fd78d0
ToppCell	PND07-28-samps-Endothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	PTPRM CYYR1 GATA2 OCLN	1.07e-04	189	58	4	eb2f8c8a90e5e9f6697a2d13274c94f40e1973e4
ToppCell	Endothelial-endothelial_cell_of_artery\|World / Lineage, Cell type, age group and donor	FAM171A1 PTPRM CYYR1 GATA2	1.07e-04	189	58	4	fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCell	tumor_Lung-MAST_cells-MAST\|tumor_Lung / Location, Cell class and cell subclass	GALC GATA2 BEX4 BHLHE40	1.07e-04	189	58	4	cd977962e01756b663728dae32ab9aba15bf7e22
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DOCK3 HNF1B LAMA3 OCLN	1.07e-04	189	58	4	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	tumor_Lung-MAST_cells\|tumor_Lung / Location, Cell class and cell subclass	GALC GATA2 BEX4 BHLHE40	1.07e-04	189	58	4	300670be76454f197bd04f82c533579dd3671969
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	PTPRM CYYR1 GATA2 OCLN	1.07e-04	189	58	4	d4a25d59d88325d3b20f4287e9b1160c82961a96
ToppCell	droplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL3 CYYR1 GATA2 LAMA3	1.09e-04	190	58	4	9d5242759546be0089981ef1877e4ed5f81face5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 DOCK3 OCLN LRP1B	1.09e-04	190	58	4	bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(general)\|COVID-19 / group, cell type (main and fine annotations)	PTPRM NFIB CYYR1 GATA2	1.09e-04	190	58	4	812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DOCK3 HNF1B LAMA3 OCLN	1.09e-04	190	58	4	c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCell	facs-Pancreas-Exocrine-3m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL3 CYYR1 GATA2 LAMA3	1.09e-04	190	58	4	b7fc451e160e31dc898b122de844b501f587db67
ToppCell	facs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l27\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FMNL3 CYYR1 GATA2 LAMA3	1.09e-04	190	58	4	632d5dc11765053366d61f0a0c7916111cea4f50
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 DOCK3 OCLN LRP1B	1.09e-04	190	58	4	b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCell	facs-SCAT-Fat-18m-Endothelial-nan\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL3 PTPRM CYYR1 GATA2	1.09e-04	190	58	4	b0c9dae8189d407c94964c6bfe3ef92035245357
ToppCell	COPD-Myeloid-Mast\|Myeloid / Disease state, Lineage and Cell class	FAM171A1 GALC GATA2 AGAP1	1.09e-04	190	58	4	379dbac19110b76079a7a53209569e060a852acb
ToppCell	facs-SCAT-Fat-18m-Endothelial\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL3 PTPRM CYYR1 GATA2	1.09e-04	190	58	4	ee63dc04e91ad49aa7820c98e97261176ecebaa6
ToppCell	human_hepatoblastoma-Endothelial_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	TANC2 FMNL3 NFIB CYYR1	1.09e-04	190	58	4	8d6ef93d69e96cd6921816d152bea3b0710cf147
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAM171A1 PTPRM EGR3 CYYR1	1.09e-04	190	58	4	f6c38d197fd9d69a4f97cb2e72cd4747984c1a86
ToppCell	facs-SCAT-Fat-18m-Endothelial-endothelial_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL3 PTPRM CYYR1 GATA2	1.09e-04	190	58	4	0e50808bfc3d0820524c8470ae3e8250819d65b2
ToppCell	facs-Pancreas-Exocrine-3m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL3 CYYR1 GATA2 LAMA3	1.09e-04	190	58	4	83cc851fb9f644b17a8ebf4d99a646003769a22f
ToppCell	facs-Pancreas-Exocrine-3m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL3 CYYR1 GATA2 LAMA3	1.09e-04	190	58	4	5f440d4b334d66d419c03bd828f7d93f16c1ce67
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FAM171A1 PTPRM NFIB CYYR1	1.12e-04	191	58	4	50601ef0a5a8f2c2120922989e08e85bf2d9b4ab
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HNF1B CECR2 LAMA3 BHLHE40	1.12e-04	191	58	4	34cc997e4e5c727495f321e6807a84aa124da486
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 DOCK3 OCLN LRP1B	1.12e-04	191	58	4	2fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FMNL3 FAM171A1 MYO1E PTPRM	1.12e-04	191	58	4	a7b18bcf27c38ad2353c239ecb309c80f3ef3359
ToppCell	Control-Endothelial-VE_Venous\|Control / Disease state, Lineage and Cell class	FAM171A1 NFIB CYYR1 GATA2	1.12e-04	191	58	4	617546cf4883dedf3323e03a53ba5adec334cf8e
ToppCell	390C-Myeloid-Mast_cell-\|390C / Donor, Lineage, Cell class and subclass (all cells)	GALC EGR3 GATA2 BHLHE40	1.12e-04	191	58	4	88bcd0b85b2112cef15c9e44d1429f9fba4a3400
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 FAM171A1 MYO1E BHLHE40	1.12e-04	191	58	4	96b78b4e819ea6052334bfcbc7abbf35897df885
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA	EGR3 NFIB CDK13 ZHX2 BHLHE40 ZIC1	4.49e-06	172	57	6	1072_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	GTF3C2 EGR3 NFIB CDK13 ZHX2 ZIC1	4.49e-06	172	57	6	6993_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	EGR3 NFIB GATA2 LAMA3 ZHX2 ZIC1	4.49e-06	172	57	6	2794_DN
Drug	trichostatin A ; Down 200; 1uM; MCF7; HT_HG-U133A_EA	EGR3 NFIB ZHX2 BHLHE40 PRRC2B ZIC1	5.30e-06	177	57	6	873_DN
Drug	genistein; Down 200; 10uM; MCF7; HT_HG-U133A	GTF3C2 RIPK1 NFIB CDK13 ZMYND8 RRM1	8.70e-06	193	57	6	5232_DN
Drug	Myosmine [532-12-7]; Down 200; 27.4uM; HL60; HT_HG-U133A	GALC FMO5 COPA ZMYND8 BHLHE40 KMO	9.22e-06	195	57	6	2199_DN
Drug	Canrenoic acid potassium salt [2181-04-6]; Down 200; 10uM; PC3; HT_HG-U133A	FMO5 GTF3C2 NFIB GATA2 BHLHE40 PRRC2B	9.50e-06	196	57	6	2065_DN
Drug	Parthenolide [20554-84-1]; Down 200; 16.2uM; MCF7; HT_HG-U133A	GALC EGR3 ZMYND8 ZHX2 ZIC1	5.48e-05	163	57	5	2885_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	EGR3 NFIB ZMYND8 ZHX2 ZIC1	5.48e-05	163	57	5	5594_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	GTF3C2 EGR3 NFIB ZHX2 ZIC1	5.48e-05	163	57	5	7453_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	GALC RIPK1 EGR3 ZHX2 ZIC1	5.64e-05	164	57	5	4388_DN
Drug	okadaic acid tetramethyl ether	GOLGA5 ZHX2	6.13e-05	5	57	2	CID000147507
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	EGR3 NFIB ZMYND8 ZHX2 ZIC1	6.51e-05	169	57	5	5231_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	GTF3C2 EGR3 NFIB ZHX2 ZIC1	6.69e-05	170	57	5	1050_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	GTF3C2 EGR3 NFIB ZHX2 ZIC1	6.69e-05	170	57	5	7043_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA	EGR3 NFIB CDK13 ZHX2 ZIC1	6.88e-05	171	57	5	1000_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	GTF3C2 EGR3 NFIB ZHX2 ZIC1	7.07e-05	172	57	5	3428_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	EGR3 NFIB LAMA3 ZHX2 ZIC1	7.07e-05	172	57	5	1637_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	RIPK1 EGR3 ZMYND8 ZHX2 ZIC1	7.27e-05	173	57	5	5987_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA	EGR3 CDK13 ZHX2 BHLHE40 ZIC1	7.68e-05	175	57	5	1014_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA	EGR3 NFIB CDK13 ZHX2 ZIC1	7.68e-05	175	57	5	1058_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	GALC EGR3 NFIB ZHX2 ZIC1	7.89e-05	176	57	5	3312_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	EGR3 NFIB ZHX2 BHLHE40 ZIC1	7.89e-05	176	57	5	6932_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	GTF3C2 EGR3 NFIB ZHX2 ZIC1	8.10e-05	177	57	5	6972_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	BRIX1 EGR3 NFIB ZHX2 ZIC1	8.10e-05	177	57	5	5308_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	GTF3C2 EGR3 GATA2 ZHX2 ZIC1	8.10e-05	177	57	5	7550_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	GTF3C2 EGR3 NFIB ZHX2 ZIC1	8.32e-05	178	57	5	1112_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	CDK13 ZMYND8 ZHX2 BHLHE40 ZIC1	8.54e-05	179	57	5	6910_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	EGR3 NFIB ZHX2 BHLHE40 ZIC1	8.54e-05	179	57	5	5484_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	GTF3C2 EGR3 NFIB ZHX2 ZIC1	8.77e-05	180	57	5	4821_DN
Drug	H-7 dihydrochloride; Down 200; 100uM; MCF7; HT_HG-U133A	BRIX1 ZNF266 EGR3 ZMYND8 GATA2	9.00e-05	181	57	5	5963_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	GTF3C2 EGR3 LAMA3 ZHX2 ZIC1	9.48e-05	183	57	5	3510_DN
Drug	LY 294002; Down 200; 10uM; MCF7; HT_HG-U133A_EA	EGR3 ZMYND8 ZHX2 BHLHE40 ZIC1	1.13e-04	190	57	5	1077_DN
Drug	Isotretinoin [4759-48-2]; Down 200; 13.4uM; MCF7; HT_HG-U133A	RIPK1 EGR3 ZMYND8 FRS2 BEX4	1.16e-04	191	57	5	7438_DN
Drug	Dorzolamide hydrochloride [130693-82-2]; Down 200; 11uM; HL60; HT_HG-U133A	GTF3C2 COPA CDK13 GATA2 RRM1	1.16e-04	191	57	5	6142_DN
Drug	Cephalexin monohydrate [23325-78-2]; Down 200; 11uM; HL60; HT_HG-U133A	BRIX1 COPA RRM1 BHLHE40 ALG13	1.19e-04	192	57	5	1273_DN
Drug	Flupentixol dihydrochloride cis-(Z) [2413-38-9]; Up 200; 7.8uM; MCF7; HT_HG-U133A	GTF3C2 RIPK1 MYO1E FRS2 BHLHE40	1.31e-04	196	57	5	5307_UP
Drug	Florfenicol [73231-34-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A	LRRC42 RIPK1 NFIB GATA2 BEX4	1.31e-04	196	57	5	6460_DN
Drug	Aminophylline [317-34-0]; Down 200; 9.6uM; PC3; HT_HG-U133A	GTF3C2 RIPK1 COPA MYO1E PRRC2B	1.31e-04	196	57	5	6295_DN
Drug	Benzonatate [104-31-4]; Down 200; 6.6uM; HL60; HT_HG-U133A	MYO1E ZMYND8 ZHX2 PRRC2B ALG13	1.31e-04	196	57	5	1843_DN
Drug	Pyridoxine hydrochloride [58-56-0]; Down 200; 19.4uM; HL60; HG-U133A	RIPK1 COPA CDK13 BHLHE40 ALG13	1.31e-04	196	57	5	1759_DN
Drug	Bisoprolol fumarate; Up 200; 9uM; HL60; HT_HG-U133A	GTF3C2 COPA MYO1E RRM1 NAGPA	1.34e-04	197	57	5	1287_UP
Drug	Chlorphensin carbamate [886-74-8]; Down 200; 16.2uM; MCF7; HT_HG-U133A	FMO5 COPA NFIB NEUROD4 ZMYND8	1.37e-04	198	57	5	2279_DN
Drug	probucol; Down 200; 10uM; MCF7; HG-U133A	FAM171A1 GALC MYO1E TMPRSS5 BHLHE40	1.37e-04	198	57	5	592_DN
Drug	Cyclopenthiazide [742-20-1]; Down 200; 10.6uM; MCF7; HT_HG-U133A	RIPK1 ZMYND8 GATA2 FRS2 LAMA3	1.37e-04	198	57	5	7325_DN
Drug	Bendroflumethiazide [73-48-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A	PTPRM EGR3 NFIB CDK13 FRS2	1.37e-04	198	57	5	3415_UP
Drug	Etidronic acid, disodium salt [7414-83-7]; Up 200; 16uM; HL60; HT_HG-U133A	FMO5 EGR3 GLI2 NEK11 ALG13	1.40e-04	199	57	5	2985_UP
Drug	Cytisine (-) [485-35-8]; Up 200; 21uM; MCF7; HT_HG-U133A	TANC2 NFIB NEUROD4 ZMYND8 NEK11	1.40e-04	199	57	5	6217_UP
Drug	tamoxifen citrate; Up 200; 1uM; ssMCF7; HG-U133A	TANC2 BRIX1 GALC TMPRSS5 AGAP1	1.44e-04	200	57	5	375_UP
Drug	lissamine	FRS2 GOLGA5 NAGPA	1.83e-04	44	57	3	CID005359521
Disease	adverse effect, response to xenobiotic stimulus	FMNL3 NFIB LRP1B	1.95e-04	59	56	3	EFO_0009658, GO_0009410
Disease	craniosynostosis (is_implicated_in)	FLNA ZIC1	2.31e-04	12	56	2	DOID:2340 (is_implicated_in)
Disease	brain age measurement	DMGDH GALC	6.58e-04	20	56	2	EFO_0010602
Disease	Epilepsy	TANC2 FLNA ALG13	1.18e-03	109	56	3	C0014544
Disease	Alzheimer disease, educational attainment	DOCK3 NFIB LRP1B AGAP1	1.25e-03	247	56	4	EFO_0011015, MONDO_0004975
Disease	Iniencephaly	CECR2 RRM1	1.30e-03	28	56	2	C0152234
Disease	level of Phosphatidylethanolamine (18:0_18:2) in blood serum	GTF3C2 MYO1E	1.30e-03	28	56	2	OBA_2045139
Disease	Tethered Cord Syndrome	CECR2 RRM1	1.30e-03	28	56	2	C0080218
Disease	Spinal Cord Myelodysplasia	CECR2 RRM1	1.30e-03	28	56	2	C0344479
Disease	Exencephaly	CECR2 RRM1	1.30e-03	28	56	2	C0266453
Disease	Neurenteric Cyst	CECR2 RRM1	1.30e-03	28	56	2	C0027806
Disease	Acrania	CECR2 RRM1	1.30e-03	28	56	2	C0702169
Disease	Diastematomyelia	CECR2 RRM1	1.30e-03	28	56	2	C0011999
Disease	Craniorachischisis	CECR2 RRM1	1.39e-03	29	56	2	C0152426
Disease	Neural Tube Defects	CECR2 RRM1	1.49e-03	30	56	2	C0027794
Disease	Epileptic encephalopathy	FLNA ALG13	1.49e-03	30	56	2	C0543888
Disease	insomnia measurement	TANC2 OR5V1 NFIB ZMYND8 AGAP1	1.52e-03	443	56	5	EFO_0007876
Disease	white matter volume measurement	RIPK1 LRP1B	1.69e-03	32	56	2	EFO_0008320

Protein segments in the cluster

Peptide	Gene	Start	Entry
YGHDPPMHYSQTAGN	ALG13	621	Q9NP73
GVLTYHPSLHDYMQN	AGAP1	376	Q9UPQ3
HYMRFQTPEPDNHYD	BEX4	101	Q9NWD9
DNNYLPYPIHQVRHM	CLK2	256	P49760
EHGDLPGMYPAHMYQ	BHLHE40	21	O14503
PTLYENPHYQSPNMH	BRIX1	251	Q8TDN6
HPHYDLDGTAYNMGN	BCO2	226	Q9BYV7
MPGLEYPNSAAHYHI	CECR2	1141	Q9BXF3
HPLPAKMHNYNYGGN	CDK13	1451	Q14004
DPLQQAYAGMHHYAA	CELF6	351	Q96J87
PYLEHVGHNHTYNMA	NFE2L1	566	Q14494
IGEIPSQPYYHDMNS	NFIB	241	O00712
HYAPSNDIYGGEMHV	OCLN	21	Q16625
HYMKLPGDHSYVSQP	FAM171A1	586	Q5VUB5
GNPSYNMYEVDHDHN	LRP1B	4491	Q9NZR2
RPENNYYFPDLHHMK	LAMA3	716	Q16787
YGHDHEMEYCADLPP	CYYR1	116	Q96J86
LLTYTPEMHHDQPYG	GOLGA5	716	Q8TBA6
PHYMSPEALKHQGYD	NEK11	196	Q8NG66
NAPHPYVNPHMEHYL	GLI2	116	P10070
MSYYLSSENHLDPGP	LRRC42	1	Q9Y546
EGYLTAPHMNDHYTN	PLBD1	106	Q6P4A8
APHMNDHYTNLYPQL	PLBD1	111	Q6P4A8
TDPHLHTPMYYFLGN	OR5V1	51	Q9UGF6
LHSHQDTYPMIYENG	POMT1	341	Q9Y6A1
HELAYDPNYMSPFAQ	PPTC7	261	Q8NI37
HLDSQGNPYYANPAH	GATA2	51	P23769
PKNGDYAMEPNYLHI	KMO	201	O15229
YGPAHMNSVERYDPS	KLHL28	441	Q9NXS3
APEDLYHHMQLAYPN	DOCK3	1706	Q8IZD9
YDNMHIPGSPLQFYV	FLNA	1846	P21333
NPTDAYQLNYDMHNP	COPA	1151	P53621
GYHNNLDPMHNYVNT	FRS2	381	Q8WU20
NLFPMIPDYNLYHHP	EGR3	186	Q06889
IPDYNLYHHPNDMGS	EGR3	191	Q06889
NYQYGFNLVMSHPHA	FMNL3	236	Q8IVF7
SDYPIPDHYPNFMHN	FMO5	71	P49326
PDHYPNFMHNAQVLE	FMO5	76	P49326
YNPGDGHIDPYSLTM	DMGDH	186	Q9UI17
GTEPSHMHYALDENY	GALC	111	P54803
QHPDYAEYIFHPMDL	ZMYND8	181	Q9ULU4
GYHRPNHYIATQGPM	PTPRM	961	P28827
HMYAHKQEPPQYSHT	HNF1B	511	P35680
MAGSHPYFNQPDSTH	SLC35G3	1	Q8N808
PYDHMLPGAEHFAEY	MPST	71	P25325
RLHGDYAYHPLQEMN	NAGPA	481	Q9UK23
YAYHPLQEMNGEPLA	NAGPA	486	Q9UK23
NGHLLEDDYYSPHGM	TANC2	1911	Q9HCD6
PYFYTQMHEIHANGG	SI	1591	P14410
NGGTLYYMAPEHLND	RIPK1	186	Q13546
LYNYINPHNGKHSPM	RRM1	101	P23921
PHPLYSAQNHDYDVA	TMPRSS5	296	Q9H3S3
SQFMGNVYHPPTYHD	PRRC2B	266	Q5JSZ5
HQHGPMPRGNYLEAD	nan	161	Q6ZUG5
YEEMPAYTHASPIHN	ZNF780B	146	Q9Y6R6
QDPGMELHLIHYSYG	TRB	56	P0DTU4
SEHYAAPQLHGYGPM	ZIC1	186	Q15915
MEQYQHQPMADDHGY	ZHX2	691	Q9Y6X8
RPHQHLAAGYYNGMV	GTF3C2	566	Q8WUA4
QDPGMELHLIHYSYG	TRBV25-1	56	A0A075B6N4
YLNIHMGTHTGDNPY	ZNF266	226	Q14584
QYENPPHIYALADNM	MYO1E	81	Q12965
DVPIDMSYDSYPHHG	NEUROD4	306	Q9HD90