Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein serine kinase activity	AURKA AURKC PLK2 VRK2 PIM2 DSTYK RPS6KB1 RPS6KB2 MASTL PLK3 AURKB	6.91e-08	363	72	11	GO:0106310
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	AURKA AURKC PLK2 VRK2 PIM2 DSTYK RPS6KB1 RPS6KB2 MASTL PLK3 AURKB	5.41e-07	446	72	11	GO:0004674
GeneOntologyMolecularFunction	protein serine/threonine/tyrosine kinase activity	AURKA AURKC DSTYK RPS6KB1 AURKB	7.22e-07	47	72	5	GO:0004712
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	AURKA AURKC CERK PLK2 VRK2 PIM2 DSTYK RPS6KB1 RPS6KB2 MASTL PLK3 AURKB	7.97e-06	709	72	12	GO:0016773
GeneOntologyMolecularFunction	protein kinase activity	AURKA AURKC PLK2 VRK2 PIM2 DSTYK RPS6KB1 RPS6KB2 MASTL PLK3 AURKB	9.43e-06	600	72	11	GO:0004672
GeneOntologyMolecularFunction	kinase activity	AURKA AURKC CERK PLK2 VRK2 PIM2 DSTYK RPS6KB1 RPS6KB2 MASTL PLK3 AURKB	1.68e-05	764	72	12	GO:0016301
GeneOntologyMolecularFunction	extracellular matrix structural constituent conferring tensile strength	COL4A2 COL4A4 COL6A1 COL6A6	2.26e-05	46	72	4	GO:0030020
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	AURKA AURKC CERK PLK2 VRK2 PIM2 DSTYK RPS6KB1 RPS6KB2 MASTL POLQ PLK3 AURKB	2.69e-05	938	72	13	GO:0016772
GeneOntologyMolecularFunction	ribosomal protein S6 kinase activity	RPS6KB1 RPS6KB2	2.66e-04	7	72	2	GO:0004711
GeneOntologyMolecularFunction	histone H3 kinase activity	AURKA AURKB	8.27e-04	12	72	2	GO:0140996
GeneOntologyBiologicalProcess	mitotic spindle organization	AURKA AURKC PLK2 CKAP5 PLK3 AURKB	1.71e-05	151	74	6	GO:0007052
GeneOntologyCellularComponent	chromosome passenger complex	AURKA AURKC AURKB	8.11e-07	6	73	3	GO:0032133
GeneOntologyCellularComponent	spindle pole centrosome	AURKA AURKC AURKB	3.80e-05	19	73	3	GO:0031616
GeneOntologyCellularComponent	kinetochore	AURKA AURKC PLK2 CKAP5 PLK3 AURKB	4.08e-05	181	73	6	GO:0000776
GeneOntologyCellularComponent	condensed chromosome, centromeric region	AURKA AURKC PLK2 CKAP5 PLK3 AURKB	5.84e-05	193	73	6	GO:0000779
GeneOntologyCellularComponent	spindle pole	AURKA AURKC PLK2 CKAP5 PLK3 AURKB	8.15e-05	205	73	6	GO:0000922
GeneOntologyCellularComponent	collagen type IV trimer	COL4A2 COL4A4	1.79e-04	6	73	2	GO:0005587
GeneOntologyCellularComponent	collagen trimer	COL4A2 COL4A4 COL6A1 COL6A6	2.56e-04	88	73	4	GO:0005581
GeneOntologyCellularComponent	basement membrane collagen trimer	COL4A2 COL4A4	3.32e-04	8	73	2	GO:0098651
GeneOntologyCellularComponent	network-forming collagen trimer	COL4A2 COL4A4	3.32e-04	8	73	2	GO:0098642
GeneOntologyCellularComponent	collagen network	COL4A2 COL4A4	3.32e-04	8	73	2	GO:0098645
GeneOntologyCellularComponent	spindle midzone	AURKA AURKC AURKB	3.68e-04	40	73	3	GO:0051233
GeneOntologyCellularComponent	chromosome, centromeric region	AURKA AURKC PLK2 CKAP5 PLK3 AURKB	4.07e-04	276	73	6	GO:0000775
GeneOntologyCellularComponent	chromosomal region	AURKA AURKC PLK2 CKAP5 TFIP11 PLK3 AURKB	6.64e-04	421	73	7	GO:0098687
GeneOntologyCellularComponent	condensed chromosome	AURKA AURKC PLK2 CKAP5 PLK3 AURKB	7.13e-04	307	73	6	GO:0000793
GeneOntologyCellularComponent	PcG protein complex	KDM2B CBX8 BAP1	7.99e-04	52	73	3	GO:0031519
GeneOntologyCellularComponent	spindle	AURKA AURKC PLK2 HECW2 CKAP5 PLK3 AURKB	1.28e-03	471	73	7	GO:0005819
GeneOntologyCellularComponent	centrosome	AURKA AURKC PLK2 CKAP5 MASTL CCT4 PLK3 AURKB PDZD2	1.40e-03	770	73	9	GO:0005813
GeneOntologyCellularComponent	chromocenter	SOX30 AURKB	1.77e-03	18	73	2	GO:0010369
GeneOntologyCellularComponent	meiotic spindle	AURKA AURKC	1.98e-03	19	73	2	GO:0072687
GeneOntologyCellularComponent	complex of collagen trimers	COL4A2 COL4A4	2.42e-03	21	73	2	GO:0098644
GeneOntologyCellularComponent	supramolecular polymer	COL4A2 AURKA COL4A4 AURKC COL6A1 EML5 MYOM3 CKAP5 CCT4 ALPG AURKB	2.63e-03	1187	73	11	GO:0099081
GeneOntologyCellularComponent	spindle microtubule	AURKA AURKC AURKB	3.40e-03	86	73	3	GO:0005876
GeneOntologyCellularComponent	axon initial segment	TRIM46 KCNQ2	4.59e-03	29	73	2	GO:0043194
GeneOntologyCellularComponent	microtubule organizing center	AURKA AURKC PLK2 CKAP5 MASTL CCT4 PLK3 AURKB PDZD2	4.60e-03	919	73	9	GO:0005815
GeneOntologyCellularComponent	basolateral plasma membrane	AURKA SLCO1C1 DSTYK ATP2C2 ST14	5.23e-03	320	73	5	GO:0016323
GeneOntologyCellularComponent	endoplasmic reticulum lumen	PCSK1 COL4A2 COL4A4 COL6A1 TXNDC5	6.10e-03	332	73	5	GO:0005788
Domain	Aur	AURKA AURKC AURKB	5.73e-08	3	73	3	IPR030616
Domain	Ser/Thr_kinase_AS	AURKA AURKC PLK2 VRK2 PIM2 DSTYK RPS6KB1 RPS6KB2 MASTL PLK3 AURKB	1.32e-07	357	73	11	IPR008271
Domain	S_TKc	AURKA AURKC PLK2 VRK2 PIM2 DSTYK RPS6KB1 RPS6KB2 MASTL PLK3 AURKB	1.39e-07	359	73	11	SM00220
Domain	PROTEIN_KINASE_ST	AURKA AURKC PLK2 VRK2 PIM2 DSTYK RPS6KB1 RPS6KB2 MASTL PLK3 AURKB	1.51e-07	362	73	11	PS00108
Domain	Pkinase	AURKA AURKC PLK2 VRK2 PIM2 DSTYK RPS6KB1 RPS6KB2 MASTL PLK3 AURKB	2.53e-07	381	73	11	PF00069
Domain	PROTEIN_KINASE_ATP	AURKA AURKC PLK2 VRK2 PIM2 DSTYK RPS6KB1 RPS6KB2 MASTL PLK3 AURKB	1.58e-06	459	73	11	PS00107
Domain	Prot_kinase_dom	AURKA AURKC PLK2 VRK2 PIM2 DSTYK RPS6KB1 RPS6KB2 MASTL PLK3 AURKB	2.91e-06	489	73	11	IPR000719
Domain	PROTEIN_KINASE_DOM	AURKA AURKC PLK2 VRK2 PIM2 DSTYK RPS6KB1 RPS6KB2 MASTL PLK3 AURKB	3.15e-06	493	73	11	PS50011
Domain	Ca/CaM-dep_Ca-dep_prot_Kinase	AURKA AURKC PLK2 PLK3 AURKB	7.34e-06	69	73	5	IPR020636
Domain	Kinase-like_dom	AURKA AURKC PLK2 VRK2 PIM2 DSTYK RPS6KB1 RPS6KB2 MASTL PLK3 AURKB	7.76e-06	542	73	11	IPR011009
Domain	Ribosomal_S6_kinase	RPS6KB1 RPS6KB2	1.51e-05	2	73	2	IPR016238
Domain	Protein_kinase_ATP_BS	AURKA AURKC PLK2 PIM2 DSTYK RPS6KB1 RPS6KB2 PLK3 AURKB	1.64e-05	379	73	9	IPR017441
Domain	POLO_box_2	PLK2 PLK3	4.51e-05	3	73	2	IPR033695
Domain	-	PLK2 PLK3	9.00e-05	4	73	2	3.30.1120.30
Domain	POLO_box	PLK2 PLK3	9.00e-05	4	73	2	PF00659
Domain	POLO_BOX	PLK2 PLK3	9.00e-05	4	73	2	PS50078
Domain	POLO_box_1	PLK2 PLK3	9.00e-05	4	73	2	IPR033701
Domain	POLO_box_dom	PLK2 PLK3	1.50e-04	5	73	2	IPR000959
Domain	C4	COL4A2 COL4A4	2.24e-04	6	73	2	SM00111
Domain	-	COL4A2 COL4A4	2.24e-04	6	73	2	2.170.240.10
Domain	Collagen_VI_NC	COL4A2 COL4A4	2.24e-04	6	73	2	IPR001442
Domain	C4	COL4A2 COL4A4	2.24e-04	6	73	2	PF01413
Domain	Peptidase_S8_Asp-AS	PCSK1 PCSK6	2.24e-04	6	73	2	IPR023827
Domain	NC1_IV	COL4A2 COL4A4	2.24e-04	6	73	2	PS51403
Domain	PrprotnconvertsP	PCSK1 PCSK6	3.12e-04	7	73	2	IPR002884
Domain	P_proprotein	PCSK1 PCSK6	3.12e-04	7	73	2	PF01483
Domain	S8_pro-domain	PCSK1 PCSK6	3.12e-04	7	73	2	IPR032815
Domain	-	PCSK1 PCSK6	3.12e-04	7	73	2	3.30.70.850
Domain	S8_pro-domain	PCSK1 PCSK6	3.12e-04	7	73	2	PF16470
Domain	Collagen	COL4A2 COL4A4 COL6A1 COL6A6	3.42e-04	85	73	4	IPR008160
Domain	Collagen	COL4A2 COL4A4 COL6A1 COL6A6	3.42e-04	85	73	4	PF01391
Domain	Peptidase_S8_His-AS	PCSK1 PCSK6	5.33e-04	9	73	2	IPR022398
Domain	Peptidase_S8_Ser-AS	PCSK1 PCSK6	5.33e-04	9	73	2	IPR023828
Domain	Peptidase_S8_subtilisin-rel	PCSK1 PCSK6	6.64e-04	10	73	2	IPR015500
Domain	SUBTILASE_ASP	PCSK1 PCSK6	6.64e-04	10	73	2	PS00136
Domain	SUBTILASE_HIS	PCSK1 PCSK6	6.64e-04	10	73	2	PS00137
Domain	SUBTILASE_SER	PCSK1 PCSK6	6.64e-04	10	73	2	PS00138
Domain	-	PCSK1 PCSK6	8.10e-04	11	73	2	3.40.50.200
Domain	Peptidase_S8/S53_dom	PCSK1 PCSK6	8.10e-04	11	73	2	IPR000209
Domain	Peptidase_S8	PCSK1 PCSK6	8.10e-04	11	73	2	PF00082
Domain	Mit_uncoupling	SLC25A32 SLC25A10	9.70e-04	12	73	2	IPR002030
Domain	AGC-kinase_C	RPS6KB1 RPS6KB2 MASTL	1.37e-03	56	73	3	IPR000961
Domain	AGC_KINASE_CTER	RPS6KB1 RPS6KB2 MASTL	1.37e-03	56	73	3	PS51285
Domain	S_TK_X	RPS6KB1 RPS6KB2 MASTL	1.37e-03	56	73	3	SM00133
Domain	Propept_inh	PCSK1 PCSK6	1.97e-03	17	73	2	IPR009020
Domain	SEA	ADGRF5 ST14	3.31e-03	22	73	2	PF01390
Domain	SEA	ADGRF5 ST14	3.61e-03	23	73	2	PS50024
Domain	SEA_dom	ADGRF5 ST14	3.61e-03	23	73	2	IPR000082
Pathway	REACTOME_NCAM1_INTERACTIONS	COL4A2 COL4A4 COL6A1 COL6A6	1.11e-06	20	57	4	MM15061
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	COL4A2 COL4A4 COL6A1 COL6A6	1.60e-05	38	57	4	MM14969
Pathway	REACTOME_COLLAGEN_CHAIN_TRIMERIZATION	COL4A2 COL4A4 COL6A1 COL6A6	2.18e-05	41	57	4	MM15538
Pathway	REACTOME_NCAM1_INTERACTIONS	COL4A2 COL4A4 COL6A1 COL6A6	2.40e-05	42	57	4	M7169
Pathway	REACTOME_COLLAGEN_CHAIN_TRIMERIZATION	COL4A2 COL4A4 COL6A1 COL6A6	2.89e-05	44	57	4	M27812
Pathway	REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES	COL4A2 COL4A4 COL6A1 COL6A6	4.82e-05	50	57	4	MM14796
Pathway	REACTOME_COLLAGEN_DEGRADATION	COL4A2 COL4A4 COL6A1 COL6A6	6.07e-05	53	57	4	MM14566
Pathway	REACTOME_SIGNALING_BY_PDGF	COL4A2 COL4A4 COL6A1 COL6A6	8.09e-05	57	57	4	MM14713
Pathway	KEGG_ACUTE_MYELOID_LEUKEMIA	TCF7L2 PIM2 RPS6KB1 RPS6KB2	8.09e-05	57	57	4	M19888
Pathway	REACTOME_SIGNALING_BY_PDGF	COL4A2 COL4A4 COL6A1 COL6A6	8.66e-05	58	57	4	M2049
Pathway	REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES	COL4A2 COL4A4 COL6A1 COL6A6	1.06e-04	61	57	4	M27103
Pathway	REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES	COL4A2 COL4A4 COL6A1 COL6A6	1.06e-04	61	57	4	MM14637
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	COL4A2 COL4A4 COL6A1 COL6A6	1.20e-04	63	57	4	M11187
Pathway	REACTOME_COLLAGEN_DEGRADATION	COL4A2 COL4A4 COL6A1 COL6A6	1.27e-04	64	57	4	M26953
Pathway	REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES	COL4A2 COL4A4 COL6A1 COL6A6	1.52e-04	67	57	4	M26999
Pathway	WP_ACUTE_MYELOID_LEUKEMIA	TCF7L2 PIM2 RPS6KB1 RPS6KB2	1.61e-04	68	57	4	M48322
Pathway	REACTOME_ECM_PROTEOGLYCANS	COL4A2 COL4A4 COL6A1 COL6A6	2.48e-04	76	57	4	M27219
Pathway	REACTOME_COLLAGEN_FORMATION	COL4A2 COL4A4 COL6A1 COL6A6	2.48e-04	76	57	4	MM14573
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	COL4A2 COL4A4 COL6A1 COL6A6	2.48e-04	76	57	4	MM14867
Pathway	PID_AURORA_A_PATHWAY	AURKA CKAP5 AURKB	2.60e-04	31	57	3	M242
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PI3K_TO_PI3K_SIGNALING_PATHWAY	RPS6KB1 RPS6KB2	3.33e-04	7	57	2	M47407
Pathway	REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CELL_CYCLE_GENES	AURKA PLK2 PLK3	3.43e-04	34	57	3	MM15325
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	COL4A2 COL4A4 COL6A1 COL6A6	3.64e-04	84	57	4	M7098
Pathway	REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS	COL4A2 COL4A4 COL6A1 COL6A6	3.81e-04	85	57	4	M16441
Pathway	REACTOME_COLLAGEN_FORMATION	COL4A2 COL4A4 COL6A1 COL6A6	4.74e-04	90	57	4	M631
Pathway	PID_AURORA_B_PATHWAY	AURKA AURKC AURKB	5.17e-04	39	57	3	M14
Pathway	BIOCARTA_NPP1_PATHWAY	COL4A2 COL4A4	7.08e-04	10	57	2	M22040
Pathway	BIOCARTA_NPP1_PATHWAY	COL4A2 COL4A4	7.08e-04	10	57	2	MM1560
Pathway	KEGG_MEDICUS_VARIANT_EGFR_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	RPS6KB1 RPS6KB2	7.08e-04	10	57	2	M47400
Pathway	WP_TRANSLATION_INHIBITORS_IN_CHRONICALLY_ACTIVATED_PDGFRA_CELLS	PIM2 RPS6KB1 RPS6KB2	8.41e-04	46	57	3	M39805
Pathway	BIOCARTA_VITCB_PATHWAY	COL4A2 COL4A4	8.63e-04	11	57	2	M15422
Pathway	KEGG_MEDICUS_REFERENCE_IGF2_IGF1R_PI3K_SIGNALING_PATHWAY	RPS6KB1 RPS6KB2	8.63e-04	11	57	2	M47484
Pathway	KEGG_MEDICUS_REFERENCE_EREG_EGFR_PI3K_SIGNALING_PATHWAY	RPS6KB1 RPS6KB2	8.63e-04	11	57	2	M47499
Pathway	KEGG_MEDICUS_REFERENCE_KITLG_KIT_PI3K_SIGNALING_PATHWAY	RPS6KB1 RPS6KB2	8.63e-04	11	57	2	M47403
Pathway	KEGG_MEDICUS_REFERENCE_AREG_EGFR_PI3K_SIGNALING_PATHWAY	RPS6KB1 RPS6KB2	8.63e-04	11	57	2	M47501
Pathway	REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CELL_CYCLE_GENES	AURKA PLK2 PLK3	1.01e-03	49	57	3	M27614
Pathway	BIOCARTA_VITCB_PATHWAY	COL4A2 COL4A4	1.03e-03	12	57	2	MM1526
Pathway	KEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	RPS6KB1 RPS6KB2	1.03e-03	12	57	2	M47393
Pathway	KEGG_MEDICUS_REFERENCE_CENPE_INTERACTION_WITH_NDC80_COMPLEX	AURKA AURKB	1.03e-03	12	57	2	M47887
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	COL4A2 COL4A4 COL6A1 COL6A6	1.15e-03	114	57	4	MM14571
Pathway	BIOCARTA_ACE2_PATHWAY	COL4A2 COL4A4	1.22e-03	13	57	2	MM1347
Pathway	KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PI3K_SIGNALING_PATHWAY	RPS6KB1 RPS6KB2	1.22e-03	13	57	2	M47398
Pathway	BIOCARTA_ACE2_PATHWAY	COL4A2 COL4A4	1.22e-03	13	57	2	M12950
Pathway	BIOCARTA_PLATELETAPP_PATHWAY	COL4A2 COL4A4	1.42e-03	14	57	2	MM1458
Pathway	BIOCARTA_PLATELETAPP_PATHWAY	COL4A2 COL4A4	1.42e-03	14	57	2	M6487
Pathway	REACTOME_LAMININ_INTERACTIONS	COL4A2 COL4A4	1.63e-03	15	57	2	MM14922
Pathway	KEGG_MEDICUS_REFERENCE_RELN_VLDLR_PI3K_SIGNALING_PATHWAY	RPS6KB1 RPS6KB2	1.63e-03	15	57	2	M47663
Pathway	REACTOME_ANCHORING_FIBRIL_FORMATION	COL4A2 COL4A4	1.63e-03	15	57	2	M27161
Pathway	REACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS	COL4A2 COL4A4	2.36e-03	18	57	2	M27164
Pathway	REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_ADDITIONAL_CELL_CYCLE_GENES_WHOSE_EXACT_ROLE_IN_THE_P53_PATHWAY_REMAIN_UNCERTAIN	PLK2 PLK3	2.36e-03	18	57	2	MM15336
Pathway	REACTOME_CROSSLINKING_OF_COLLAGEN_FIBRILS	COL4A2 COL4A4	2.36e-03	18	57	2	MM14882
Pathway	WP_PI3KAKT_SIGNALING	COL4A2 COL4A4 COL6A1 COL6A6 RPS6KB1 RPS6KB2	2.39e-03	339	57	6	M39736
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	COL4A2 COL4A4 COL6A1 COL6A6	2.45e-03	140	57	4	M587
Pathway	BIOCARTA_AMI_PATHWAY	COL4A2 COL4A4	2.91e-03	20	57	2	M15394
Pathway	REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_ADDITIONAL_CELL_CYCLE_GENES_WHOSE_EXACT_ROLE_IN_THE_P53_PATHWAY_REMAIN_UNCERTAIN	PLK2 PLK3	3.21e-03	21	57	2	M27634
Pathway	REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLUCAGON_LIKE_PEPTIDE_1_GLP_1	PCSK1 TCF7L2	3.21e-03	21	57	2	M932
Pathway	PID_AVB3_INTEGRIN_PATHWAY	COL4A4 COL6A1 RPS6KB1	3.32e-03	74	57	3	M160
Pathway	BIOCARTA_INTRINSIC_PATHWAY	COL4A2 COL4A4	3.85e-03	23	57	2	M15997
Pathway	BIOCARTA_INTRINSIC_PATHWAY	COL4A2 COL4A4	3.85e-03	23	57	2	MM1427
Pathway	KEGG_MEDICUS_REFERENCE_MICROTUBULE_DEPOLYMERIZATION	AURKA AURKB	3.85e-03	23	57	2	M47910
Pathway	KEGG_MEDICUS_REFERENCE_KINETOCHORE_FIBER_ORGANIZATION	AURKA CKAP5	3.85e-03	23	57	2	M47900
Pathway	REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION	PCSK1 TCF7L2	4.19e-03	24	57	2	M928
Pathway	WP_IL18_SIGNALING	USP5 AARS1 ABCF1 SLC12A3 RPS6KB1	4.84e-03	273	57	5	M39818
Pathway	KEGG_MEDICUS_REFERENCE_DEUBIQUITINATION_OF_H2AK119	CBX8 BAP1	4.91e-03	26	57	2	M47923
Pubmed	Aurora kinase B inhibits aurora kinase A to control maternal mRNA translation in mouse oocytes.	AURKA AURKC AURKB	9.25e-09	3	74	3	34636397
Pubmed	Deregulation of Aurora kinase gene expression in human testicular germ cell tumours.	AURKA AURKC AURKB	9.25e-09	3	74	3	20629650
Pubmed	Differential Selective Pressures Experienced by the Aurora Kinase Gene Family.	AURKA AURKC AURKB	9.25e-09	3	74	3	29283376
Pubmed	SNS-314, a pan-Aurora kinase inhibitor, shows potent anti-tumor activity and dosing flexibility in vivo.	AURKA AURKC AURKB	9.25e-09	3	74	3	19649632
Pubmed	SAR156497, an exquisitely selective inhibitor of aurora kinases.	AURKA AURKC AURKB	9.25e-09	3	74	3	25369539
Pubmed	Gene expression of Aurora kinases in prostate cancer and nodular hyperplasia tissues.	AURKA AURKC AURKB	9.25e-09	3	74	3	23075505
Pubmed	Aurora kinase mRNA expression is reduced with increasing gestational age and in severe early onset fetal growth restriction.	AURKA AURKC AURKB	9.25e-09	3	74	3	32452402
Pubmed	Specialize and Divide (Twice): Functions of Three Aurora Kinase Homologs in Mammalian Oocyte Meiotic Maturation.	AURKA AURKC AURKB	9.25e-09	3	74	3	28359584
Pubmed	Genetic Interactions between the Aurora Kinases Reveal New Requirements for AURKB and AURKC during Oocyte Meiosis.	AURKA AURKC AURKB	9.25e-09	3	74	3	30415701
Pubmed	The aurora kinases in cell cycle and leukemia.	AURKA AURKC AURKB	9.25e-09	3	74	3	24632603
Pubmed	Aurora A, centrosome structure, and the centrosome cycle.	AURKA AURKC AURKB	9.25e-09	3	74	3	19774610
Pubmed	Regulation of spindle and chromatin dynamics during early and late stages of oocyte maturation by aurora kinases.	AURKA AURKC AURKB	9.25e-09	3	74	3	18353803
Pubmed	Characterization and risk association of polymorphisms in Aurora kinases A, B and C with genetic susceptibility to gastric cancer development.	AURKA AURKC AURKB	9.25e-09	3	74	3	31521144
Pubmed	Caenorhabditis elegans Aurora A kinase AIR-1 is required for postembryonic cell divisions and germline development.	AURKA AURKC AURKB	9.25e-09	3	74	3	12434334
Pubmed	Identification of the substrates and interaction proteins of aurora kinases from a protein-protein interaction model.	AURKA AURKC AURKB	5.14e-07	8	74	3	14602875
Pubmed	Centrosome-related genes, genetic variation, and risk of breast cancer.	AURKC PLK2 CKAP5 PLK3 AURKB	2.70e-06	102	74	5	20508983
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	AURKA PLK2 HECW2 RPS6KB1 RPS6KB2 ATP2C2 TNFAIP1 PLK3 BAP1 AURKB	3.34e-06	730	74	10	34857952
Pubmed	Daurinol Enhances the Efficacy of Radiotherapy in Lung Cancer via Suppression of Aurora Kinase A/B Expression.	AURKA AURKB	4.47e-06	2	74	2	25882311
Pubmed	Gene expression profiles of the aurora family kinases.	AURKA AURKB	4.47e-06	2	74	2	16572587
Pubmed	Aurora B expression in metastatic effusions from advanced-stage ovarian serous carcinoma is predictive of intrinsic chemotherapy resistance.	AURKA AURKB	4.47e-06	2	74	2	23114921
Pubmed	Polymorphisms in MicroRNA Binding Sites Predict Colorectal Cancer Survival.	RPS6KB1 ZNF839	4.47e-06	2	74	2	28138309
Pubmed	Activation of Mechanistic Target of Rapamycin (mTOR) in Human Endothelial Cells Infected with Pathogenic Spotted Fever Group Rickettsiae.	RPS6KB1 RPS6KB2	4.47e-06	2	74	2	33003310
Pubmed	Using ZINC08918027 inhibitor to determine Aurora kinase-chromosomal passenger complex isoforms in mouse oocytes.	AURKA AURKC	4.47e-06	2	74	2	35255953
Pubmed	Validating Aurora B as an anti-cancer drug target.	AURKA AURKB	4.47e-06	2	74	2	16912073
Pubmed	Aurora kinases as targets in drug-resistant neuroblastoma cells.	AURKA AURKB	4.47e-06	2	74	2	25268132
Pubmed	Differential expression of AURKA and AURKB genes in bone marrow stromal mesenchymal cells of myelodysplastic syndrome: correlation with G-banding analysis and FISH.	AURKA AURKB	4.47e-06	2	74	2	23092930
Pubmed	Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway.	RPS6KB1 RPS6KB2	4.47e-06	2	74	2	18758466
Pubmed	Different interactomes for p70-S6K1 and p54-S6K2 revealed by proteomic analysis.	RPS6KB1 RPS6KB2	4.47e-06	2	74	2	27493124
Pubmed	Purging human ovarian cortex of contaminating leukaemic cells by targeting the mitotic catastrophe signalling pathway.	AURKC AURKB	4.47e-06	2	74	2	33725274
Pubmed	Mantle cell lymphoma harboring Burkitt's-like translocations presents differential expression of aurora kinase genes compared with others 8q abnormalities.	AURKA AURKB	4.47e-06	2	74	2	24683001
Pubmed	Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells.	AURKC AURKB	4.47e-06	2	74	2	15499654
Pubmed	Aurora kinase genetic polymorphisms: an association study in Down syndrome and spontaneous abortion.	AURKA AURKC	4.47e-06	2	74	2	35218477
Pubmed	Deregulated expression of Aurora kinases is not a prognostic biomarker in papillary thyroid cancer patients.	AURKA AURKB	4.47e-06	2	74	2	25807528
Pubmed	An integrated genomic approach to identify predictive biomarkers of response to the aurora kinase inhibitor PF-03814735.	AURKA AURKB	4.47e-06	2	74	2	22222631
Pubmed	Overexpression of Aurora-C interferes with the spindle checkpoint by promoting the degradation of Aurora-B.	AURKC AURKB	4.47e-06	2	74	2	24603334
Pubmed	Targeting aurora kinases as a potential prognostic and therapeutical biomarkers in pediatric acute lymphoblastic leukaemia.	AURKA AURKB	4.47e-06	2	74	2	33277547
Pubmed	Identification and characterization of Aurora kinase B and C variants associated with maternal aneuploidy.	AURKC AURKB	4.47e-06	2	74	2	28369513
Pubmed	Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases.	AURKA AURKB	4.47e-06	2	74	2	11784863
Pubmed	Mitotic kinases as regulators of cell division and its checkpoints.	AURKA AURKB	4.47e-06	2	74	2	11413462
Pubmed	Association of the AURKA and AURKC gene polymorphisms with an increased risk of gastric cancer.	AURKA AURKB	4.47e-06	2	74	2	27270838
Pubmed	Functions and regulation of the 70kDa ribosomal S6 kinases.	RPS6KB1 RPS6KB2	4.47e-06	2	74	2	20932932
Pubmed	Aurora/Ipl1p-related kinases, a new oncogenic family of mitotic serine-threonine kinases.	AURKA AURKB	4.47e-06	2	74	2	10523496
Pubmed	Expression of mitotic kinases phospho-aurora A and aurora B correlates with clinical and pathological parameters in bladder neoplasms.	AURKA AURKB	4.47e-06	2	74	2	20865660
Pubmed	Single nucleotide polymorphisms rs911160 in AURKA and rs2289590 in AURKB mitotic checkpoint genes contribute to gastric cancer susceptibility.	AURKA AURKB	4.47e-06	2	74	2	28843004
Pubmed	S6 kinase deletion suppresses muscle growth adaptations to nutrient availability by activating AMP kinase.	RPS6KB1 RPS6KB2	4.47e-06	2	74	2	17550782
Pubmed	Removal of S6K1 and S6K2 leads to divergent alterations in learning, memory, and synaptic plasticity.	RPS6KB1 RPS6KB2	4.47e-06	2	74	2	18174371
Pubmed	High expression of AURKA and AURKB is associated with unfavorable cytogenetic abnormalities and high white blood cell count in patients with acute myeloid leukemia.	AURKA AURKB	4.47e-06	2	74	2	20732714
Pubmed	Growth suppression and mitotic defect induced by JNJ-7706621, an inhibitor of cyclin-dependent kinases and aurora kinases.	AURKA AURKB	4.47e-06	2	74	2	22463590
Pubmed	In vivo modulation of polo-like kinases supports a key role for PLK2 in Ser129 α-synuclein phosphorylation in mouse brain.	PLK2 PLK3	4.47e-06	2	74	2	24128992
Pubmed	Unique and Redundant Functions of p70 Ribosomal S6 Kinase Isoforms Regulate Mesenchymal Cell Proliferation and Migration in Pulmonary Fibrosis.	RPS6KB1 RPS6KB2	4.47e-06	2	74	2	27438654
Pubmed	Structures of collagen IV globular domains: insight into associated pathologies, folding and network assembly.	COL4A2 COL4A4	4.47e-06	2	74	2	30443360
Pubmed	Selective disruption of aurora C kinase reveals distinct functions from aurora B kinase during meiosis in mouse oocytes.	AURKC AURKB	4.47e-06	2	74	2	24586209
Pubmed	Aurora kinase A and B as new treatment targets in aromatase inhibitor-resistant breast cancer cells.	AURKA AURKB	4.47e-06	2	74	2	25667100
Pubmed	Loss of Aurora Kinase Signaling Allows Lung Cancer Cells to Adopt Endoreplication and Form Polyploid Giant Cancer Cells That Resist Antimitotic Drugs.	AURKA AURKB	4.47e-06	2	74	2	33172929
Pubmed	Investigation on PLK2 and PLK3 substrate recognition.	PLK2 PLK3	4.47e-06	2	74	2	22828320
Pubmed	Aurora B and C kinases regulate chromosome desynapsis and segregation during mouse and human spermatogenesis.	AURKC AURKB	4.47e-06	2	74	2	33172986
Pubmed	Pharmacogenetic profiling of Aurora kinase B is associated with overall survival in metastatic colorectal cancer.	AURKA AURKB	4.47e-06	2	74	2	20368716
Pubmed	Gene amplification of ribosomal protein S6 kinase-1 and -2 in gastric cancer.	RPS6KB1 RPS6KB2	4.47e-06	2	74	2	23393338
Pubmed	Expression of Aurora A (but not Aurora B) is predictive of survival in breast cancer.	AURKA AURKB	4.47e-06	2	74	2	18628459
Pubmed	Aurora kinase inhibition sensitizes melanoma cells to T-cell-mediated cytotoxicity.	AURKA AURKB	4.47e-06	2	74	2	33123754
Pubmed	High aurora kinase expression identifies patients with muscle-invasive bladder cancer who have poor survival after neoadjuvant chemotherapy.	AURKA AURKB	4.47e-06	2	74	2	31597600
Pubmed	Vesicular stomatitis virus oncolysis is potentiated by impairing mTORC1-dependent type I IFN production.	RPS6KB1 RPS6KB2	4.47e-06	2	74	2	20080710
Pubmed	Spindle assembly checkpoint gene expression in childhood adrenocortical tumors (ACT): Overexpression of Aurora kinases A and B is associated with a poor prognosis.	AURKA AURKB	4.47e-06	2	74	2	23788275
Pubmed	Expression of Aurora kinase A and B in normal and malignant cervical tissue: high Aurora A kinase expression in squamous cervical cancer.	AURKA AURKB	4.47e-06	2	74	2	19059698
Pubmed	Aurora kinases in childhood acute leukemia: the promise of aurora B as therapeutic target.	AURKA AURKB	4.47e-06	2	74	2	22940834
Pubmed	Midostaurin preferentially attenuates proliferation of triple-negative breast cancer cell lines through inhibition of Aurora kinase family.	AURKA AURKB	4.47e-06	2	74	2	26141684
Pubmed	Antitumor Activity of KW-2450 against Triple-Negative Breast Cancer by Inhibiting Aurora A and B Kinases.	AURKA AURKB	4.47e-06	2	74	2	26443806
Pubmed	Allosteric modulation of a human protein kinase with monobodies.	AURKA AURKB	4.47e-06	2	74	2	31239342
Pubmed	Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase.	RPS6KB1 RPS6KB2	4.47e-06	2	74	2	9822608
Pubmed	Protein kinase C phosphorylates ribosomal protein S6 kinase betaII and regulates its subcellular localization.	RPS6KB1 RPS6KB2	4.47e-06	2	74	2	12529391
Pubmed	Molecular cloning and characterization of a novel p70 S6 kinase, p70 S6 kinase beta containing a proline-rich region.	RPS6KB1 RPS6KB2	4.47e-06	2	74	2	9804755
Pubmed	A Dual Non-ATP Analogue Inhibitor of Aurora Kinases A and B, Derived from Resorcinol with a Mixed Mode of Inhibition.	AURKA AURKB	4.47e-06	2	74	2	26808391
Pubmed	New Treatment of Medullary and Papillary Human Thyroid Cancer: Biological Effects of Hyaluronic Acid Hydrogel Loaded With Quercetin Alone or in Combination to an Inhibitor of Aurora Kinase.	AURKA AURKB	4.47e-06	2	74	2	26660542
Pubmed	Clinical potential of the mTOR targets S6K1 and S6K2 in breast cancer.	RPS6KB1 RPS6KB2	4.47e-06	2	74	2	20953835
Pubmed	Aurora kinases as prognostic biomarkers in ovarian carcinoma.	AURKA AURKB	4.47e-06	2	74	2	19157502
Pubmed	Antiproliferative effect of Aurora kinase targeting in mesothelioma.	AURKA AURKB	4.47e-06	2	74	2	20371132
Pubmed	Spatial Compartmentalization Specializes the Function of Aurora A and Aurora B.	AURKA AURKB	4.47e-06	2	74	2	25987563
Pubmed	S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway.	RPS6KB1 RPS6KB2	4.47e-06	2	74	2	15060135
Pubmed	Maternally recruited Aurora C kinase is more stable than Aurora B to support mouse oocyte maturation and early development.	AURKC AURKB	4.47e-06	2	74	2	22778418
Pubmed	Constitutively active Akt1 expression in mouse pancreas requires S6 kinase 1 for insulinoma formation.	RPS6KB1 RPS6KB2	4.47e-06	2	74	2	18846252
Pubmed	Expression of aurora kinase A and B in chondrosarcoma and its relationship with the prognosis.	AURKA AURKB	4.47e-06	2	74	2	22809428
Pubmed	Boolean modeling identifies Greatwall/MASTL as an important regulator in the AURKA network of neuroblastoma.	AURKA MASTL	4.47e-06	2	74	2	26616283
Pubmed	Genetic variations in AURORA cell cycle kinases are associated with glioblastoma multiforme.	AURKC AURKB	4.47e-06	2	74	2	34465813
Pubmed	Metabolic control by S6 kinases depends on dietary lipids.	RPS6KB1 RPS6KB2	4.47e-06	2	74	2	22412899
Pubmed	Differential functions of the Aurora-B and Aurora-C kinases in mammalian spermatogenesis.	AURKC AURKB	4.47e-06	2	74	2	17192404
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	COL4A2 USP5 AARS1 ABCF1 TXNDC5 RPS6KB1 ETFA SLC25A10 MASTL CCT4	8.05e-06	807	74	10	30575818
Pubmed	Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis.	AURKA AURKB	1.34e-05	3	74	2	17726514
Pubmed	mTOR/S6 kinase pathway contributes to astrocyte survival during ischemia.	RPS6KB1 RPS6KB2	1.34e-05	3	74	2	19535330
Pubmed	BUB1 mRNA is significantly co-expressed with AURKA and AURKB mRNA in advanced-stage ovarian serous carcinoma.	AURKA AURKB	1.34e-05	3	74	2	24756216
Pubmed	The chromosome passenger complex is required for fidelity of chromosome transmission and cytokinesis in meiosis of mouse oocytes.	AURKC AURKB	1.34e-05	3	74	2	21123620
Pubmed	Specific interaction between S6K1 and CoA synthase: a potential link between the mTOR/S6K pathway, CoA biosynthesis and energy metabolism.	RPS6KB1 RPS6KB2	1.34e-05	3	74	2	15589845
Pubmed	Adhesion induced expression of the serine/threonine kinase Fnk in human macrophages.	PLK2 PLK3	1.34e-05	3	74	2	11039900
Pubmed	Dynamic localization and functional implications of Aurora-C kinase during male mouse meiosis.	AURKC AURKB	1.34e-05	3	74	2	16386730
Pubmed	Molecular distinctions between Aurora A and B: a single residue change transforms Aurora A into correctly localized and functional Aurora B.	AURKA AURKB	1.34e-05	3	74	2	19494039
Pubmed	Functional impact of Aurora A-mediated phosphorylation of HP1γ at serine 83 during cell cycle progression.	AURKA AURKB	1.34e-05	3	74	2	23829974
Pubmed	Collagen types in various layers of the human aorta and their changes with the atherosclerotic process.	COL4A2 COL4A4	1.34e-05	3	74	2	3089234
Pubmed	Modulation of epigenetic factors during the early stages of HIV-1 infection in CD4+ T cells in vitro.	AURKC AURKB	1.34e-05	3	74	2	30077875
Pubmed	Cell cycle-dependent nuclear export of phosphatase and tensin homologue tumor suppressor is regulated by the phosphoinositide-3-kinase signaling cascade.	RPS6KB1 RPS6KB2	1.34e-05	3	74	2	18006852
Pubmed	The polo-like protein kinases Fnk and Snk associate with a Ca(2+)- and integrin-binding protein and are regulated dynamically with synaptic plasticity.	PLK2 PLK3	1.34e-05	3	74	2	10523297
Pubmed	High-throughput kinase inhibitor screening reveals roles for Aurora and Nuak kinases in neurite initiation and dendritic branching.	AURKA AURKB	1.34e-05	3	74	2	33854138
Interaction	AURKC interactions	AURKA AURKC FKBP5 AURKB	1.85e-05	43	74	4	int:AURKC
Interaction	SGK2 interactions	RPS6KB1 RPS6KB2 CCT4 FKBP5	1.85e-05	43	74	4	int:SGK2
Interaction	TCEAL4 interactions	AURKA ATXN2L USP5 AURKB	2.43e-05	46	74	4	int:TCEAL4
GeneFamily	Collagens	COL4A2 COL4A4 COL6A1 COL6A6	5.53e-06	46	46	4	490
GeneFamily	Proprotein convertase subtilisin/kexin family	PCSK1 PCSK6	2.25e-04	9	46	2	973
GeneFamily	Solute carriers	SLC25A32 SLC12A3 SLCO1C1 SLC22A23 SLC25A10	3.19e-03	395	46	5	752
GeneFamily	Ubiquitin specific peptidases	USP53 USP5	8.94e-03	56	46	2	366
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	AURKA ELL AURKB	1.09e-02	181	46	3	694
Coexpression	VANTVEER_BREAST_CANCER_BRCA1_UP	THEMIS2 VRK2 PIM2 KDM2B	2.55e-06	34	74	4	M16737
Coexpression	NABA_BASEMENT_MEMBRANES	COL4A2 COL4A4 COL6A1 COL6A6	4.95e-06	40	74	4	M5887
Coexpression	NABA_COLLAGENS	COL4A2 COL4A4 COL6A1 COL6A6	6.64e-06	43	74	4	MM17060
Coexpression	NABA_COLLAGENS	COL4A2 COL4A4 COL6A1 COL6A6	7.29e-06	44	74	4	M3005
Coexpression	FINETTI_BREAST_CANCER_KINOME_RED	AURKA MASTL AURKB	1.18e-05	16	74	3	M9389
Coexpression	GSE37534_UNTREATED_VS_GW1929_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN	COL4A2 KCTD3 CKAP5 TNFAIP1 POLQ AURKB	2.14e-05	199	74	6	M8979
Coexpression	MARTINEZ_RB1_AND_TP53_TARGETS_DN	ATXN2L AURKC AARS1 TENM4 SUPT6H DSTYK SLC25A10 ST14 FKBP5	5.43e-05	610	74	9	M3854
Coexpression	MARTINEZ_TP53_TARGETS_DN	ATXN2L AURKC AARS1 TENM4 SUPT6H DSTYK SLC25A10 ST14 FKBP5	5.78e-05	615	74	9	M8673
Coexpression	HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP	TRIM46 AURKA AARS1 CKAP5 AURKB	7.39e-05	153	74	5	M5588
Coexpression	HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP	TRIM46 AURKA AARS1 CKAP5 AURKB	7.86e-05	155	74	5	MM1259
Coexpression	MARTINEZ_RB1_AND_TP53_TARGETS_DN	ATXN2L AURKC AARS1 TENM4 SUPT6H DSTYK SLC25A10 ST14 FKBP5	8.82e-05	650	74	9	MM1042
Coexpression	MARTINEZ_TP53_TARGETS_DN	ATXN2L AURKC AARS1 TENM4 SUPT6H DSTYK SLC25A10 ST14 FKBP5	9.79e-05	659	74	9	MM1040
ToppCell	LA-01._Fibroblast_I\|LA / Chamber and Cluster_Paper	COL4A4 COL6A1 COL6A6 PCSK6 KIAA1755 KAZN FKBP5	2.02e-08	179	74	7	dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	COL4A2 COL4A4 COL6A1 COL6A6 PCSK6 KAZN FKBP5	2.72e-08	187	74	7	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	COVID-19-Heart-Fib_1\|Heart / Disease (COVID-19 only), tissue and cell type	COL4A4 COL6A1 TENM4 PCSK6 THUMPD1 KIAA1755 KAZN	3.63e-08	195	74	7	f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	COL4A2 COL4A4 SLC22A23 KHDRBS2 ADGRF5 PDZD2	3.99e-07	170	74	6	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	LV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	COL4A2 USP53 COL4A4 COL6A1 THUMPD1 FKBP5	7.65e-07	190	74	6	12992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCell	RV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	COL4A2 COL4A4 COL6A1 PCSK6 KAZN FKBP5	7.89e-07	191	74	6	70c067c54084bfb02c29bab085f4defd477194fb
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	COL4A2 HECW2 SLC22A23 PCSK6 ADGRF5 DENND3	8.38e-07	193	74	6	479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCell	LV-02._Fibroblast_II\|LV / Chamber and Cluster_Paper	COL4A2 USP53 COL4A4 COL6A1 KAZN FKBP5	8.64e-07	194	74	6	014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell	COVID-19-Heart-Fib_2\|Heart / Disease (COVID-19 only), tissue and cell type	COL4A4 COL6A1 TENM4 PCSK6 KIAA1755 KAZN	8.64e-07	194	74	6	d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell	LA-02._Fibroblast_II\|LA / Chamber and Cluster_Paper	COL4A2 USP53 COL4A4 PCSK6 KAZN FKBP5	8.64e-07	194	74	6	234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCell	RV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	COL4A2 COL4A4 COL6A1 PCSK6 KAZN FKBP5	8.90e-07	195	74	6	ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 PLK2 FCGRT HECW2 ADGRF5 TNFAIP1	9.17e-07	196	74	6	81900dcc9451ff6606ec940c16b559d73247590e
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 PLK2 FCGRT HECW2 ADGRF5 TNFAIP1	9.44e-07	197	74	6	d584d0334ea97e3fa8c4cd869f5eeea2c7a1ed04
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 PLK2 FCGRT HECW2 ADGRF5 TNFAIP1	9.44e-07	197	74	6	412091994196a06c2779b4c2cfed84be889a5f8d
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A4 COL6A1 PLK2 LCTL SOX30	4.52e-06	146	74	5	669001b772b6d6109a09727619ed5829122b48db
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AURKA CKAP5 MASTL POLQ AURKB	8.69e-06	167	74	5	d21635df8b74189e3309eaf435af381fbe412574
ToppCell	Control\|World / group, cell type (main and fine annotations)	SLC22A23 ATP2C2 KHDRBS2 ADGRF5 PDZD2	8.95e-06	168	74	5	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	COL4A2 COL4A4 KHDRBS2 DENND3 PDZD2	1.06e-05	174	74	5	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	367C-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SLC25A10 CKAP5 MASTL POLQ AURKB	1.09e-05	175	74	5	0b1aaa028ba844d4bcb4509fdab8bee648373935
ToppCell	facs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A4 COL6A1 TENM4 PCSK6 KIAA1755	1.12e-05	176	74	5	fee4e0f32aaf77294040c7af6c1f503571750d43
ToppCell	facs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A4 COL6A1 TENM4 PCSK6 KIAA1755	1.12e-05	176	74	5	f25251abd4ef9fb077a978f9f9f658af58e4e0d2
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 PLK2 ADGRF5 TNFAIP1 POLQ	1.18e-05	178	74	5	ba2f0585626988b511046630bc16be5c5fec3fb2
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL4A2 COL4A4 KHDRBS2 DENND3 PDZD2	1.22e-05	179	74	5	4f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PLK2 SLC22A23 PCSK6 ADGRF5 DENND3	1.25e-05	180	74	5	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	Control-Endothelial_cells-Capillary_endothelial_cells\|Control / group, cell type (main and fine annotations)	COL4A2 HECW2 KHDRBS2 KCTD3 FKBP5	1.25e-05	180	74	5	b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TCF7L2 CKAP5 MASTL ALPG AURKB	1.35e-05	183	74	5	e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL4A2 COL4A4 KHDRBS2 DENND3 PDZD2	1.39e-05	184	74	5	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D122\|Adult / Lineage, Cell type, age group and donor	COL4A2 COL4A4 KHDRBS2 DENND3 PDZD2	1.39e-05	184	74	5	561592edc3083fad41b91811151b442207c65dd9
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL4A2 COL4A4 KHDRBS2 DENND3 PDZD2	1.39e-05	184	74	5	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AURKA TCF7L2 CKAP5 MASTL POLQ	1.39e-05	184	74	5	16aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL4A2 COL4A4 KHDRBS2 DENND3 PDZD2	1.43e-05	185	74	5	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL4A2 SLC22A23 PCSK6 PNPLA8 DENND3	1.43e-05	185	74	5	673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AURKA CKAP5 POLQ AURKB CNDP1	1.43e-05	185	74	5	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	IPF-Epithelial-ATI\|Epithelial / Disease state, Lineage and Cell class	COL4A2 COL4A4 KHDRBS2 ADGRF5 DENND3	1.46e-05	186	74	5	d436ee6cabbde8553ec5e6e55022274090d9f41a
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1\|Adult / Lineage, Cell type, age group and donor	COL4A2 COL4A4 KHDRBS2 DENND3 PDZD2	1.50e-05	187	74	5	77f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL4A4 COL6A1 TENM4 PCSK6 KIAA1755	1.54e-05	188	74	5	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AURKA TENM4 CKAP5 MASTL AURKB	1.54e-05	188	74	5	95d0a796d62ce6d121e2028c378faffc14b35275
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 PLK2 SLCO1C1 FCGRT ADGRF5	1.54e-05	188	74	5	4dc89c7843ebd078e3414e835c56f11fa27f0c5f
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 PLK2 SLCO1C1 FCGRT ADGRF5	1.54e-05	188	74	5	d577b3c2a844e3062c7ca9e9ebc1722d0ac95caa
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 PLK2 SLCO1C1 FCGRT ADGRF5	1.54e-05	188	74	5	1e788b60dd643bf220d8dfafa82d85fd083cbc71
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL4A4 COL6A1 COL6A6 PCSK6 KIAA1755	1.54e-05	188	74	5	bba6b273bd47dd0e27fde914e9e6fc9d76fd5176
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL4A2 HECW2 KHDRBS2 KCTD3 ADGRF5	1.58e-05	189	74	5	b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AURKA CKAP5 MASTL POLQ AURKB	1.58e-05	189	74	5	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D231\|Adult / Lineage, Cell type, age group and donor	COL4A2 COL4A4 KHDRBS2 DENND3 PDZD2	1.58e-05	189	74	5	5a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCell	Control-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	COL4A2 HECW2 KHDRBS2 ADGRF5 FKBP5	1.62e-05	190	74	5	7f3f419fffe02934b6f27b697f7a6401072491ed
ToppCell	facs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l27\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL4A2 PLK2 HECW2 ADGRF5 DENND3	1.62e-05	190	74	5	632d5dc11765053366d61f0a0c7916111cea4f50
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL4A2 COL4A4 KHDRBS2 DENND3 PDZD2	1.62e-05	190	74	5	30b50d183d7649146eb1e79b47ba897355f1998a
ToppCell	human_hepatoblastoma-Endothelial_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	COL4A2 PLK2 HECW2 ADGRF5 PDZD2	1.62e-05	190	74	5	8d6ef93d69e96cd6921816d152bea3b0710cf147
ToppCell	LV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	USP53 COL4A4 COL6A1 PCSK6 FKBP5	1.66e-05	191	74	5	d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	AURKA CKAP5 MASTL POLQ AURKB	1.70e-05	192	74	5	27723f4e320e49d4a3daafa2d8d3946ff79fab64
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A4 COL6A1 TXNDC5 PCSK6 KIAA1755	1.70e-05	192	74	5	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 SLCO1C1 FCGRT ADGRF5 DENND3	1.70e-05	192	74	5	9d53b42cdb537b30233cdfdc08052c8b13a1113f
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	COL4A2 COL4A4 COL6A1 KAZN FKBP5	1.70e-05	192	74	5	356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A4 PLK2 ADGRF5 TNFAIP1 DENND3	1.70e-05	192	74	5	2bfac6b3956265205ca47d06888851ed68b65999
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 COL6A1 TXNDC5 COL6A6 PCSK6	1.70e-05	192	74	5	beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCell	COVID-19_Severe-Plasmablast\|World / disease group, cell group and cell class	COL4A4 AARS1 TXNDC5 PIM2 POLQ	1.70e-05	192	74	5	a333053fe2bd206c32790916bfc5fce904ab7f57
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 SLCO1C1 FCGRT ADGRF5 DENND3	1.70e-05	192	74	5	042391162df2e3d0027688dd14163c4c6821afe0
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 SLCO1C1 FCGRT ADGRF5 DENND3	1.70e-05	192	74	5	9ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 SLCO1C1 FCGRT ADGRF5 DENND3	1.70e-05	192	74	5	71b0bfee0461ff64cef35881db3959c517e9731b
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A4 COL6A1 TXNDC5 PCSK6 KIAA1755	1.70e-05	192	74	5	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 SLCO1C1 FCGRT ADGRF5 DENND3	1.70e-05	192	74	5	a116db7dec495e5a0ba9c7537057cd1e567d7885
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 SLCO1C1 FCGRT ADGRF5 DENND3	1.70e-05	192	74	5	66defad13bd8e79319741e43ddb056841710b1d7
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A4 PLK2 ADGRF5 TNFAIP1 DENND3	1.70e-05	192	74	5	d525f7f088a53110912600a7c9f6d33b9270d534
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 PLK2 SLCO1C1 FCGRT ADGRF5	1.75e-05	193	74	5	e4b440d50ae7391b26924778be6d9d53e0692449
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 PLK2 SLCO1C1 FCGRT ADGRF5	1.75e-05	193	74	5	e523dc5751f6fdcd4fc1a62b1eecd43f6ae79da9
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AURKA TENM4 CKAP5 MASTL AURKB	1.75e-05	193	74	5	a332dfdcc48c405020014e644aa4d14fda98cc86
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM46 TMEM30B PLK2 TXNDC5 ATP2C2	1.75e-05	193	74	5	5a92697430f16c49e19a5f727d289d7bd1ece31c
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 PLK2 SLCO1C1 FCGRT ADGRF5	1.75e-05	193	74	5	1772f2ac217727de63c4a9303881b3a19a6bb0f0
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-secretory_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRIM46 TMEM30B PLK2 TXNDC5 ATP2C2	1.75e-05	193	74	5	64bcdbb422f8da6fc3275e82f6aaf562f546a180
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	COL4A2 COL4A4 COL6A1 KAZN FKBP5	1.75e-05	193	74	5	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	COVID-19_Severe-Plasmablast\|COVID-19_Severe / disease group, cell group and cell class	COL4A4 AARS1 TXNDC5 PIM2 POLQ	1.75e-05	193	74	5	8074bcede261b85f9ae03ee372bd6d4b40384537
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL4A2 USP53 COL6A1 KIAA1755 KAZN	1.75e-05	193	74	5	261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCell	BAL-Severe-Lymphocyte-B-Plasmablast-Plasmablast-Developping_Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL4A4 TXNDC5 PIM2 POLQ AURKB	1.75e-05	193	74	5	0373984547cefc0cbd77f8e795d508f6fcebc6c8
ToppCell	facs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 PLK2 ADGRF5 TNFAIP1 DENND3	1.79e-05	194	74	5	c8b9551b93a5aed62154b487db90130604a6125c
ToppCell	RV-02._Fibroblast_II\|RV / Chamber and Cluster_Paper	COL4A2 COL4A4 COL6A1 KAZN FKBP5	1.79e-05	194	74	5	11c79a8c56ece42713b04b321982e41e239f07a5
ToppCell	droplet-Heart-nan-3m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 TXNDC5 COL6A6 PCSK6 KIAA1755	1.79e-05	194	74	5	ce32e60bcea1b8baf496ce9050832bc8c77d8434
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CERK PLK2 SLC12A3 PIM2 KCTD3	1.79e-05	194	74	5	11709704079f24a730476572dc2f01e9d2226e2c
ToppCell	IPF-Stromal-Pericyte\|Stromal / Disease state, Lineage and Cell class	COL4A2 SLCO1C1 ADGRF5 DENND3 PDZD2	1.79e-05	194	74	5	3892b188f424ffb80f3c75a1b6709a21c1e1601d
ToppCell	droplet-Heart-nan-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A1 TXNDC5 COL6A6 PCSK6 KIAA1755	1.79e-05	194	74	5	a1dc157148885cc8d3685ac81a1f4e3562aeecc9
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CERK PLK2 SLC12A3 PIM2 KCTD3	1.79e-05	194	74	5	3a1f95639d5f239f001bd67d4213e8938e7f299d
ToppCell	nucseq-Epithelial-Epithelial_Alveolar\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL4A4 SLC22A23 KHDRBS2 ADGRF5 PDZD2	1.79e-05	194	74	5	53f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell	facs-Thymus-nan-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AURKA MASTL POLQ FKBP5 AURKB	1.84e-05	195	74	5	93c345e70d6c8ff5d12fd63d73228c1700b804a0
ToppCell	LA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	COL4A2 COL4A4 COL6A1 PCSK6 KAZN	1.84e-05	195	74	5	a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell	RA-02._Fibroblast_II\|RA / Chamber and Cluster_Paper	COL4A2 USP53 COL4A4 KAZN FKBP5	1.84e-05	195	74	5	6a02ebbeb3199447ddce64d92d8809436e040eba
ToppCell	facs-Lung-nan-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 HECW2 PCSK6 ADGRF5 DENND3	1.84e-05	195	74	5	7f9b7f15006610ad591063d90e90367bd6083c7f
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AURKA CKAP5 MASTL ADGRF5 AURKB	1.88e-05	196	74	5	20383d576708b7e4bfce3e9fe40548cce496e3cb
ToppCell	IPF-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	COL4A2 HECW2 KHDRBS2 ADGRF5 FKBP5	1.88e-05	196	74	5	8f0f72ead06abe02b575e443552eacc2151077ef
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AURKA CKAP5 MASTL ADGRF5 AURKB	1.88e-05	196	74	5	0644bd14a944b9c9759a295dfdd5e67a4775f20a
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL4A2 COL4A4 TXNDC5 HECW2 ADGRF5	1.88e-05	196	74	5	12d9028f90c057c6e5cff00301793fa550e86c5a
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 PLK2 FCGRT HECW2 ADGRF5	1.93e-05	197	74	5	deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 PLK2 FCGRT HECW2 ADGRF5	1.93e-05	197	74	5	a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL4A2 PLK2 HECW2 ADGRF5 TNFAIP1	1.93e-05	197	74	5	15d1e0dffee8f5ba8cee37adfbfa0551a0cd5e15
ToppCell	(0)_NK_cells-(0)_NK_Dividing\|(0)_NK_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	AURKA SLC25A10 MASTL POLQ AURKB	1.98e-05	198	74	5	d9cdbc7d420472cb1ffb36ad9c8e53a61b7dbdeb
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	AURKA SLC25A10 CKAP5 POLQ AURKB	1.98e-05	198	74	5	6981cd5b1585c8ae6febdf0c4fb83067127f106c
ToppCell	PBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast-Developping_Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	AURKA AARS1 TXNDC5 POLQ AURKB	1.98e-05	198	74	5	2d8d4eb21b4fe3cc178b3518b3ea39c2d9650f24
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 PLK2 FCGRT HECW2 ADGRF5	1.98e-05	198	74	5	f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A4 SLC22A23 ATP2C2 ADGRF5 PDZD2	2.02e-05	199	74	5	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Sepsis-Leuk-UTI-Lymphocyte-B-Plasmablast\|Leuk-UTI / Disease, condition lineage and cell class	TRIM46 TXNDC5 SLC25A10 POLQ AURKB	2.02e-05	199	74	5	1b17e6d5e6b994dec65efae2667f4f1f438161b1
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell\|2m / Sample Type, Dataset, Time_group, and Cell type.	AURKA CKAP5 MASTL POLQ AURKB	2.07e-05	200	74	5	0d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells\|2m / Sample Type, Dataset, Time_group, and Cell type.	AURKA CKAP5 MASTL POLQ AURKB	2.07e-05	200	74	5	0675f580ccef705875854247bbfd4ee2bcf126a1
Drug	Amethopterin (R,S) [59-05-2]; Down 200; 8.8uM; HL60; HG-U133A	THEMIS2 COL4A2 AURKA TCF7L2 PIM2 DENND3 AURKB	3.04e-06	192	74	7	1599_DN
Drug	PHA-00851261E [724719-49-7]; Down 200; 10uM; PC3; HT_HG-U133A	COL4A2 COL6A1 SUPT6H TFIP11 TNFAIP1 PLK3 CBX8	3.04e-06	192	74	7	4330_DN
Drug	Progesterone [57-83-0]; Down 200; 12.8uM; PC3; HT_HG-U133A	COL4A2 USP5 CCSER2 TFIP11 PLK3 DENND3 CBX8	3.14e-06	193	74	7	6646_DN
Drug	Loracarbef [121961-22-6]; Up 200; 10.8uM; HL60; HT_HG-U133A	COL4A2 COL6A1 SUPT6H KAZN ZNF428 ST14 DENND3	3.36e-06	195	74	7	2970_UP
Drug	2-propylpentanoic acid; Down 200; 50uM; HL60; HT_HG-U133A	COL4A2 ATXN2L TCF7L2 DSTYK PCSK6 KAZN PLK3	3.60e-06	197	74	7	6181_DN
Drug	Dacarbazine [4342-03-4]; Down 200; 22uM; MCF7; HT_HG-U133A	PIM2 DSTYK PCSK6 TFIP11 ZNF839 PLK3 CBX8	3.72e-06	198	74	7	6816_DN
Drug	Mecamylamine hydrochloride [826-39-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A	COL6A1 USP5 PIM2 SUPT6H KAZN ZNF839 CBX8	3.72e-06	198	74	7	7023_UP
Drug	VX680	AURKA AURKC AURKB	5.34e-06	11	74	3	ctd:C484810
Drug	2-((3-((4-((5-(2-((3-fluorophenyl)amino)-2-oxoethyl)-1H-pyrazol-3-yl)amino)quinazolin-7-yl)oxy)propyl)(ethyl)amino)ethyl dihydrogen phosphate	AURKC AURKB	1.04e-05	2	74	2	ctd:C520647
Drug	Promethazine hydrochloride [58-33-3]; Down 200; 12.4uM; HL60; HT_HG-U133A	COL4A2 PCSK6 RPS6KB2 TNFAIP1 KAZN ZNF428	3.94e-05	193	74	6	3100_DN
Drug	pioglitazone HCl; Down 200; 10uM; PC3; HT_HG-U133A	AURKC PLK2 ATP2C2 CCSER2 TNFAIP1 DENND3	4.06e-05	194	74	6	6893_DN
Drug	Moricizine hydrochloride [31883-05-3]; Up 200; 8.6uM; HL60; HT_HG-U133A	ATXN2L COL6A1 DSTYK CCSER2 ST14 FKBP5	4.06e-05	194	74	6	2959_UP
Drug	Betonicine [515-25-3]; Down 200; 25.2uM; PC3; HT_HG-U133A	COL6A1 SUPT6H TFIP11 ADGRF5 PLK3 CBX8	4.06e-05	194	74	6	4301_DN
Drug	RH 1	RPS6KB1 RPS6KB2 CYB5R3 TNFAIP1	4.09e-05	59	74	4	CID000394347
Drug	Esculin Hydrate [531-75-9]; Down 200; 11.8uM; PC3; HT_HG-U133A	COL4A2 PIM2 FCGRT SUPT6H TFIP11 TNFAIP1	4.17e-05	195	74	6	6310_DN
Drug	Gossypol [303-45-7]; Down 200; 7.8uM; PC3; HT_HG-U133A	SUPT6H ATP2C2 ADGRF5 DENND3 CBX8 BAP1	4.29e-05	196	74	6	4296_DN
Drug	genistein; Down 200; 10uM; HL60; HT_HG-U133A	COL4A2 USP5 TCF7L2 PCSK6 KAZN ST14	4.42e-05	197	74	6	2695_DN
Drug	Raloxifene hydrochloride [82640-04-8]; Down 200; 7.8uM; HL60; HT_HG-U133A	COL4A2 TCF7L2 CCSER2 KAZN ST14 ELL	4.42e-05	197	74	6	2738_DN
Drug	Tetracycline hydrochloride [64-75-5]; Down 200; 8.4uM; PC3; HT_HG-U133A	TCF7L2 SUPT6H TFIP11 TNFAIP1 ZNF839 ELL	4.54e-05	198	74	6	2080_DN
Drug	clozapine; Up 200; 10uM; HL60; HT_HG-U133A	TCF7L2 SLCO1C1 PIM2 PLK3 ELL BAP1	4.54e-05	198	74	6	1170_UP
Drug	Hydrocotarnine hydrobromide [5985-00-2]; Down 200; 13.2uM; MCF7; HT_HG-U133A	ATXN2L USP5 TCF7L2 PIM2 SUPT6H CBX8	4.54e-05	198	74	6	6827_DN
Drug	Levopropoxyphene napsylate [5714-90-9]; Up 200; 7.4uM; HL60; HT_HG-U133A	ATXN2L PCSK6 RPS6KB2 BRD9 CCSER2 ZNF428	4.54e-05	198	74	6	2980_UP
Drug	Tolnaftate [2398-96-1]; Down 200; 13uM; MCF7; HT_HG-U133A	COL6A1 USP5 PIM2 SUPT6H DSTYK PCSK6	4.54e-05	198	74	6	4805_DN
Drug	Pyrimethamine [58-14-0]; Down 200; 16uM; PC3; HT_HG-U133A	COL6A1 PIM2 SUPT6H ZNF428 ELL CBX8	4.54e-05	198	74	6	4194_DN
Drug	rosiglitazone; Down 200; 10uM; HL60; HT_HG-U133A	COL4A2 ATXN2L USP5 TCF7L2 KHDRBS2 ZNF428	4.67e-05	199	74	6	2693_DN
Drug	Iproniazide phosphate [305-33-9]; Up 200; 14.4uM; PC3; HT_HG-U133A	SUPT6H KHDRBS2 ZNF428 PLK3 ELL DENND3	4.81e-05	200	74	6	6359_UP
Drug	Arcaine sulfate [14923-17-2]; Down 200; 14.8uM; HL60; HT_HG-U133A	COL4A2 COL6A1 TCF7L2 DSTYK KAZN PLK3	4.81e-05	200	74	6	3010_DN
Drug	MLN 8237	AURKA AURKB	6.23e-05	4	74	2	ctd:C550258
Drug	SQ20006	RPS6KB1 RPS6KB2	1.04e-04	5	74	2	CID000162356
Drug	x MC	RPS6KB1 RPS6KB2 CCT4	1.39e-04	31	74	3	CID000017563
Drug	VX-680	AURKA AURKC AURKB	1.39e-04	31	74	3	CID005494449
Drug	UKI-1D	FCGRT ST14	1.55e-04	6	74	2	CID003392032
Drug	SP600125	AURKA AURKC PIM2 RPS6KB1 RPS6KB2 TNFAIP1 PDZD2	1.75e-04	362	74	7	CID000008515
Drug	Dexamethasone acetate [1177-87-3]; Down 200; 9.2uM; PC3; HT_HG-U133A	TCF7L2 PIM2 SUPT6H TFIP11 ZNF839	3.70e-04	188	74	5	2079_DN
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A	COL4A2 USP53 SLCO1C1 PCSK6 DENND3	3.70e-04	188	74	5	5596_UP
Drug	LY 294002; Down 200; 10uM; HL60; HT_HG-U133A	ATXN2L PIM2 KAZN ZNF839 PLK3	3.70e-04	188	74	5	6186_DN
Drug	cupric oxide	AURKA PLK2 ABCF1 CKAP5 PNPLA8 TFIP11 ELL AURKB	3.76e-04	543	74	8	ctd:C030973
Drug	Ketoconazole [65277-42-1]; Up 200; 7.6uM; HL60; HT_HG-U133A	COL4A2 DSTYK RPS6KB2 KAZN ST14	3.79e-04	189	74	5	1285_UP
Drug	Leflunomide [75706-12-6]; Up 200; 14.8uM; HL60; HT_HG-U133A	ATXN2L AURKC DSTYK PCSK6 CCSER2	3.88e-04	190	74	5	2539_UP
Drug	GSK-3beta Inhibitor VIII; Down 200; 10uM; PC3; HT_HG-U133A	COL4A2 TENM4 DSTYK TNFAIP1 PDZD2	3.97e-04	191	74	5	7070_DN
Drug	Benzylpenicillin sodium [69-57-8]; Down 200; 11.2uM; MCF7; HT_HG-U133A	ATXN2L TCF7L2 PIM2 DSTYK ATP2C2	3.97e-04	191	74	5	6839_DN
Drug	Cotinine (-) [486-56-6]; Down 200; 22.6uM; PC3; HG-U133A	SLC25A32 PLK2 TCF7L2 KCTD3 THUMPD1	4.07e-04	192	74	5	1929_DN
Drug	Tolbutamide [64-77-7]; Down 200; 14.8uM; PC3; HT_HG-U133A	THEMIS2 AURKC ADGRF5 FKBP5 DENND3	4.07e-04	192	74	5	3804_DN
Drug	Etilefrine hydrochloride [534-87-2]; Down 200; 18.4uM; HL60; HT_HG-U133A	COL4A2 TCF7L2 KAZN ZNF428 ST14	4.17e-04	193	74	5	2930_DN
Drug	Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Up 200; 5.8uM; MCF7; HT_HG-U133A	PCSK6 TNFAIP1 KAZN CBX8 PDZD2	4.17e-04	193	74	5	6846_UP
Drug	Iodixanol [92339-11-2]; Down 200; 2.6uM; MCF7; HT_HG-U133A	PIM2 TNFAIP1 KAZN FKBP5 ELL	4.27e-04	194	74	5	4848_DN
Drug	chlorpromazine hydrochloride; Down 200; 1uM; PC3; HT_HG-U133A	USP5 TCF7L2 FCGRT KAZN POLQ	4.27e-04	194	74	5	1217_DN
Drug	Beta-Escin [11072-93-8]; Down 200; 3.2uM; PC3; HT_HG-U133A	ATXN2L TENM4 SOX30 DENND3 CBX8	4.27e-04	194	74	5	3807_DN
Drug	geldanamycin; Down 200; 1uM; HL60; HT_HG-U133A	SLC25A32 USP5 TCF7L2 CCSER2 FKBP5	4.27e-04	194	74	5	1169_DN
Drug	Oxyphenbutazone [129-20-4]; Down 200; 12.4uM; HL60; HT_HG-U133A	PCSK6 CCSER2 KAZN ZNF428 PLK3	4.27e-04	194	74	5	6160_DN
Drug	Skimmianine [83-95-4]; Down 200; 15.4uM; HL60; HT_HG-U133A	COL4A2 PIM2 PCSK6 TNFAIP1 KAZN	4.27e-04	194	74	5	2504_DN
Drug	Tetramisole hydrochloride [16595-80-5]; Down 200; 16.6uM; MCF7; HT_HG-U133A	ATXN2L PIM2 DSTYK ELL CBX8	4.37e-04	195	74	5	4412_DN
Drug	Phenelzine sulfate [156-51-4]; Down 200; 17uM; PC3; HT_HG-U133A	COL6A1 TCF7L2 TENM4 KAZN PLK3	4.37e-04	195	74	5	3802_DN
Drug	Metaraminol bitartrate [33402-03-8]; Down 200; 8.6uM; PC3; HT_HG-U133A	COL6A1 PIM2 DSTYK TFIP11 DENND3	4.37e-04	195	74	5	3669_DN
Drug	Trimethoprim [738-70-5]; Up 200; 13.8uM; PC3; HT_HG-U133A	USP5 TCF7L2 ATP2C2 ZNF428 ELL	4.37e-04	195	74	5	7377_UP
Drug	haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A	COL6A1 PIM2 DSTYK POLQ ALPG	4.37e-04	195	74	5	5200_UP
Drug	Doxylamine succinate [562-10-7]; Down 200; 10.2uM; PC3; HT_HG-U133A	ATXN2L COL6A1 FKBP5 ELL CBX8	4.37e-04	195	74	5	4235_DN
Drug	Nialamide [51-12-7]; Down 200; 13.4uM; MCF7; HT_HG-U133A	ATXN2L USP5 ZNF428 ST14 ELL	4.37e-04	195	74	5	3871_DN
Drug	Procyclidine hydrochloride [1508-76-5]; Up 200; 12.4uM; MCF7; HT_HG-U133A	SUPT6H DSTYK PLK3 CBX8 BAP1	4.37e-04	195	74	5	4817_UP
Drug	sodium 4-phenylbutyrate; Down 200; 1000uM; PC3; HG-U133A	COL6A1 SUPT6H DSTYK CCSER2 TFIP11	4.37e-04	195	74	5	434_DN
Drug	Clofazimine [2030-63-9]; Up 200; 8.4uM; PC3; HT_HG-U133A	ATXN2L PCSK6 SOX30 ATP2C2 DENND3	4.37e-04	195	74	5	4682_UP
Drug	Dilazep dihydrochloride [20153-98-4]; Up 200; 6uM; HL60; HT_HG-U133A	DSTYK PCSK6 ADGRF5 KAZN ZNF428	4.37e-04	195	74	5	2333_UP
Drug	Betulinic acid [472-15-1]; Up 200; 8.8uM; HL60; HT_HG-U133A	COL4A2 BRD9 KAZN ZNF839 PLK3	4.37e-04	195	74	5	1345_UP
Drug	Oxybutynin chloride [1508-65-2]; Down 200; 10.2uM; MCF7; HT_HG-U133A	SUPT6H PCSK6 ZNF428 FKBP5 CBX8	4.37e-04	195	74	5	6770_DN
Drug	Etofenamate [30544-47-9]; Down 200; 10.8uM; MCF7; HT_HG-U133A	TCF7L2 PIM2 SUPT6H DSTYK TFIP11	4.37e-04	195	74	5	7327_DN
Drug	quercetin dihydrate; Up 200; 1uM; MCF7; HT_HG-U133A_EA	CERK TENM4 KHDRBS2 TNFAIP1 ELL	4.47e-04	196	74	5	917_UP
Drug	rosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A	COL6A1 PIM2 DSTYK PCSK6 PLK3	4.47e-04	196	74	5	5230_UP
Drug	Harpagoside [19210-12-9]; Down 200; 8uM; HL60; HT_HG-U133A	TCF7L2 SUPT6H PCSK6 ZNF428 ZNF839	4.47e-04	196	74	5	2935_DN
Drug	Chlorpromazine hydrochloride [69-09-0]; Down 200; 11.2uM; HL60; HT_HG-U133A	FCGRT TFIP11 ZNF428 ZNF839 BAP1	4.47e-04	196	74	5	1864_DN
Drug	Piperine [94-62-2]; Up 200; 14uM; MCF7; HT_HG-U133A	COL6A1 PIM2 PCSK6 ZNF428 PLK3	4.47e-04	196	74	5	3263_UP
Drug	Orphenadrine hydrochloride [341-69-5]; Down 200; 13uM; MCF7; HT_HG-U133A	ATXN2L COL6A1 TCF7L2 PIM2 DSTYK	4.47e-04	196	74	5	2318_DN
Drug	Gossypol [303-45-7]; Down 200; 7.8uM; PC3; HT_HG-U133A	THEMIS2 TFIP11 ADGRF5 ELL CBX8	4.47e-04	196	74	5	3740_DN
Drug	Hesperidin [520-26-3]; Down 200; 6.6uM; HL60; HT_HG-U133A	TCF7L2 PIM2 FCGRT SUPT6H DSTYK	4.47e-04	196	74	5	1294_DN
Drug	Diclofenac sodium [15307-79-6]; Down 200; 12.6uM; PC3; HT_HG-U133A	COL4A2 TENM4 CCSER2 THUMPD1 PDZD2	4.47e-04	196	74	5	5861_DN
Drug	Fenspiride hydrochloride [5053-08-7]; Down 200; 13.4uM; PC3; HT_HG-U133A	COL6A1 TCF7L2 PIM2 DSTYK ZNF839	4.47e-04	196	74	5	7298_DN
Drug	Triamterene [396-01-0]; Down 200; 15.8uM; PC3; HT_HG-U133A	SUPT6H ADGRF5 ZNF839 PLK3 ELL	4.47e-04	196	74	5	1819_DN
Drug	PNU-0293363 [326823-19-2]; Down 200; 10uM; PC3; HT_HG-U133A	COL4A2 AURKA TCF7L2 CCSER2 AURKB	4.47e-04	196	74	5	6563_DN
Drug	(d,l)-Tetrahydroberberine [522-97-4]; Down 200; 11.8uM; MCF7; HT_HG-U133A	COL6A1 TCF7L2 PIM2 PCSK6 KAZN	4.47e-04	196	74	5	2818_DN
Drug	Prilocaine hydrochloride [1786-81-8]; Down 200; 15.6uM; MCF7; HT_HG-U133A	ATXN2L TCF7L2 DSTYK FKBP5 BAP1	4.47e-04	196	74	5	2314_DN
Drug	Tocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A	PIM2 SUPT6H PCSK6 ZNF428 ELL	4.47e-04	196	74	5	3256_UP
Drug	Butamben [94-25-7]; Down 200; 20.6uM; HL60; HT_HG-U133A	COL4A2 TCF7L2 FCGRT KHDRBS2 FKBP5	4.47e-04	196	74	5	2531_DN
Drug	Lymecycline [992-21-2]; Down 200; 6.6uM; HL60; HT_HG-U133A	THEMIS2 TCF7L2 RPS6KB2 TFIP11 BAP1	4.47e-04	196	74	5	2953_DN
Drug	Sulfaguanidine [57-67-0]; Up 200; 18.6uM; PC3; HT_HG-U133A	SLCO1C1 PCSK6 KHDRBS2 KAZN ALPG	4.47e-04	196	74	5	4257_UP
Drug	Nortriptyline hydrochloride [894-71-3]; Up 200; 13.4uM; PC3; HT_HG-U133A	THEMIS2 USP5 CCSER2 ZNF428 DENND3	4.47e-04	196	74	5	7300_UP
Drug	Raloxifene hydrochloride [82640-04-8]; Down 200; 7.8uM; PC3; HT_HG-U133A	COL6A1 TFIP11 KAZN ZNF428 ZNF839	4.47e-04	196	74	5	5759_DN
Drug	CGX 0596987; Down 200; 20uM; MCF7; HT_HG-U133A	ATXN2L COL6A1 PCSK6 ADGRF5 ELL	4.58e-04	197	74	5	6412_DN
Drug	Ioversol [87771-40-2]; Down 200; 5uM; HL60; HT_HG-U133A	ATXN2L USP5 TCF7L2 ZNF428 ELL	4.58e-04	197	74	5	3026_DN
Drug	Metoclopramide monohydrochloride [7232-21-5]; Down 200; 11.8uM; PC3; HT_HG-U133A	COL6A1 DSTYK TFIP11 ZNF428 ELL	4.58e-04	197	74	5	3728_DN
Drug	Diazoxide [364-98-7]; Down 200; 17.4uM; PC3; HT_HG-U133A	USP5 SUPT6H ATP2C2 CCSER2 ST14	4.58e-04	197	74	5	5810_DN
Drug	Chlorthalidone [77-36-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A	TCF7L2 PIM2 TFIP11 TNFAIP1 KAZN	4.58e-04	197	74	5	6800_DN
Drug	Trolox [53188-07-1]; Up 200; 16uM; PC3; HT_HG-U133A	COL6A1 ATP2C2 CCSER2 ZNF428 ELL	4.58e-04	197	74	5	7304_UP
Drug	Demeclocycline hydrochloride [64-73-3]; Down 200; 8uM; HL60; HT_HG-U133A	ATXN2L USP5 TCF7L2 PCSK6 CCSER2	4.58e-04	197	74	5	2545_DN
Drug	rottlerin; Down 200; 10uM; MCF7; HT_HG-U133A_EA	USP5 TCF7L2 PIM2 TFIP11 ST14	4.58e-04	197	74	5	825_DN
Drug	Trimetazidine dihydrochloride [13171-25-0]; Down 200; 11.8uM; MCF7; HT_HG-U133A	USP5 PIM2 PCSK6 CCSER2 TNFAIP1	4.58e-04	197	74	5	5479_DN
Drug	Furaltadone hydrochloride [3759-92-0]; Down 200; 11uM; HL60; HT_HG-U133A	COL4A2 TCF7L2 CCSER2 ZNF428 CBX8	4.58e-04	197	74	5	2554_DN
Drug	Bephenium hydroxynaphthoate [3818-50-6]; Down 200; 9uM; MCF7; HT_HG-U133A	USP5 TCF7L2 DSTYK KHDRBS2 ELL	4.58e-04	197	74	5	6466_DN
Drug	Fenofibrate [49562-28-9]; Up 200; 11uM; HL60; HT_HG-U133A	USP53 ATXN2L TCF7L2 SOX30 ST14	4.58e-04	197	74	5	2401_UP
Drug	aspirin, USP; Down 200; 100uM; HL60; HT_HG-U133A	USP5 TCF7L2 BRD9 FKBP5 AURKB	4.58e-04	197	74	5	1145_DN
Drug	Benzylpenicillin sodium [69-57-8]; Down 200; 11.2uM; PC3; HT_HG-U133A	AURKC COL6A1 SUPT6H ELL DENND3	4.58e-04	197	74	5	4501_DN
Drug	Cefmetazole sodium salt [56796-39-5]; Up 200; 8.2uM; HL60; HT_HG-U133A	ATXN2L TCF7L2 CCSER2 TNFAIP1 ST14	4.58e-04	197	74	5	2524_UP
Disease	body mass index, fasting blood glucose measurement	PCSK1 TCF7L2 ETFA KDM2B	7.89e-06	51	73	4	EFO_0004340, EFO_0004465
Disease	multiple acyl-CoA dehydrogenase deficiency (implicated_via_orthology)	SLC25A32 ETFA	1.81e-05	3	73	2	DOID:0060358 (implicated_via_orthology)
Disease	brain cancer (implicated_via_orthology)	AURKA AURKC AURKB	3.63e-05	26	73	3	DOID:1319 (implicated_via_orthology)
Disease	prostate carcinoma in situ (is_marker_for)	AURKA ST14 AURKB	4.55e-05	28	73	3	DOID:8634 (is_marker_for)
Disease	Aneuploidy	AURKA CKAP5	6.01e-05	5	73	2	C0002938
Disease	migraine disorder, HOMA-B	TCF7L2 ETFA	6.01e-05	5	73	2	EFO_0004469, MONDO_0005277
Disease	type 2 diabetes mellitus (implicated_via_orthology)	PCSK1 TCF7L2 RPS6KB1 RPS6KB2	1.36e-04	105	73	4	DOID:9352 (implicated_via_orthology)
Disease	Chromosomal Instability	AURKA CKAP5	1.67e-04	8	73	2	C1257806
Disease	alcohol dependence (implicated_via_orthology)	RPS6KB1 RPS6KB2	2.15e-04	9	73	2	DOID:0050741 (implicated_via_orthology)
Disease	Alzheimer disease, fasting blood glucose measurement	TCF7L2 ETFA	2.15e-04	9	73	2	EFO_0004465, MONDO_0004975
Disease	brain measurement, neuroimaging measurement	ATXN2L VRK2 TCF7L2 DSTYK KIAA1755 DENND3 CBX8	4.24e-04	550	73	7	EFO_0004346, EFO_0004464
Disease	ovary epithelial cancer (is_marker_for)	AURKA PLK3	4.63e-04	13	73	2	DOID:2152 (is_marker_for)
Disease	urinary albumin to creatinine ratio	TRIM46 COL4A4 TCF7L2 KAZN	1.03e-03	179	73	4	EFO_0007778
Disease	corneal hysteresis	COL6A1 TCF7L2	1.11e-03	20	73	2	EFO_0010066
Disease	Renal glomerular disease	COL4A4 SLC12A3	1.48e-03	23	73	2	C0268731
Disease	Glomerulopathy Assessment	COL4A4 SLC12A3	1.48e-03	23	73	2	C4521256
Disease	cortical thickness	COL4A2 VRK2 TCF7L2 KCTD3 KIAA1755 ELL DENND3 CBX8 PDZD2	1.67e-03	1113	73	9	EFO_0004840
Disease	aspartate aminotransferase measurement	TRIM46 PCSK1 FCGRT DSTYK ETFA KHDRBS2 KAZN ELL	1.74e-03	904	73	8	EFO_0004736
Disease	fasting blood glucose measurement, HOMA-B, fasting blood insulin measurement	TCF7L2 ETFA	1.75e-03	25	73	2	EFO_0004465, EFO_0004466, EFO_0004469
Disease	grip strength measurement	ATXN2L TCF7L2 SLCO1C1 KCTD3 KDM2B	1.77e-03	350	73	5	EFO_0006941
Disease	glucose metabolism disease (implicated_via_orthology)	RPS6KB1 RPS6KB2	2.19e-03	28	73	2	DOID:4194 (implicated_via_orthology)
Disease	primary biliary cholangitis (biomarker_via_orthology)	SLCO1C1 RPS6KB1	2.19e-03	28	73	2	DOID:12236 (biomarker_via_orthology)
Disease	handedness	ATXN2L VRK2 PCSK6	2.33e-03	106	73	3	EFO_0009902

Protein segments in the cluster

Peptide	Gene	Start	Entry
RYGLVGPNGKGKTTL	ABCF1	331	Q8NE71
GRPLGKGKFGNVYLA	AURKC	46	Q9UQB9
AGGRYLGKKVQFRKP	ELL	151	P55199
GRPLGKGKFGNVYLA	AURKA	136	O14965
KGGGLGNKYVQLNVG	TNFAIP1	21	Q13829
RFLPGGKMGYLKRNG	BRD9	316	Q9H8M2
ISRGAFGKVYLGQKG	MASTL	41	Q96GX5
VYGSGKKYIGPCGGR	COL4A4	36	P53420
KGFGPGYLGGFLLVL	COL4A4	1456	P53420
LKGYLGAKGIQGMPG	COL4A2	1001	P08572
GDKGAPGIFGLKGYR	COL4A2	1281	P08572
LRYKGKGTGKPGALS	BAP1	416	Q92560
KLGPLAFYKGLVPAG	SLC25A10	246	Q9UBX3
GSRGLGQGTPKGKIY	DENND3	1136	A2RUS2
KKLGFSGGGRQYQAL	ATP2C2	11	O75185
SVPGQQGKYRGAKGS	ATXN2L	736	Q8WWM7
EFRGPSGLLVYQGKG	CYB5R3	141	P00387
RKEGVGGFYKGIAPN	SLC25A32	271	Q9H2D1
YRKLETKGYGQGPGK	HECW2	1201	Q9P2P5
PRYGFGEAGKPKFGI	FKBP5	221	Q13451
KYKAGRLPLGKIGRG	KAZN	716	Q674X7
GKGRTYGSKYPGLIK	KIAA1755	236	Q5JYT7
AFKALGGKGPYTLQG	FCGRT	101	P55899
FEYGIKKGRQGLGSI	PCSK6	326	P29122
RNGGVYPGPSGEKKL	KCNQ2	6	O43526
GAGAGKPPKRNAFYR	KCNQ2	61	O43526
APGLKLRGTGLYKAA	LCTL	216	Q6UWM7
PVFGDYGEKRRGGKK	PDZD2	91	O15018
FELLRVLGKGGYGKV	RPS6KB1	91	P23443
VLGKGGYGKVFQVRK	RPS6KB1	96	P23443
KPKLGQELGRGQYGV	DSTYK	651	Q6XUX3
LYGNGPGYVLKDGAR	ALPG	411	P10696
LGYGFNRPYAAGGKK	CCSER2	286	Q9H7U1
GLAVGLRKKFGQYAG	CKAP5	346	Q14008
QKRGPGFKYASNLPG	KDM2B	731	Q8NHM5
GEPSAGLGEYLKGRK	CBX8	216	Q9HC52
DIAPRGVKGAKGYRG	COL6A1	561	P12109
FINPFGGKGQGKRIY	CERK	136	Q8TCT0
QAVGKGLLPMGRGKY	POLQ	2271	O75417
GGKNPFLGIAYLVVG	TMEM30B	311	Q3MIR4
YPKFNFVGKLLGPRG	KHDRBS2	71	Q5VWX1
GNGKRLFYRMPGGKE	EML5	471	Q05BV3
GPGYIDIPKGKGKQF	FAM135B	841	Q49AJ0
GGGFLGRKKVPYLAS	KCTD3	761	Q9Y597
CYGTKGPKGNRGLNG	COL6A6	1441	A6NMZ7
KNPYAQGRGKFFGLF	OR2H1	261	Q9GZK4
LVGGYIGGLVPKLKY	PNPLA8	301	Q9NP80
LKSGFGTYPGRKRGA	TRIM46	106	Q7Z4K8
CFELLRVLGKGGYGK	RPS6KB2	66	Q9UBS0
RVLGKGGYGKVFQVR	RPS6KB2	71	Q9UBS0
PFLGGLGGGYQKTLV	SLC22A23	86	A1A5C7
EYRLGPLLGKGGFGT	PIM2	31	Q9P1W9
GGRGLKSGENFKLLY	ETFA	221	P13804
AGGRGKGAYQDRDKP	CCT4	16	P50991
PGPALGYFRGDEKGK	SOX30	171	O94993
RKGYGILPGFKGVTV	ADGRF5	206	Q8IZF2
GKLYGRGATDNKGPV	CNDP1	156	Q96KN2
DFEIGRPLGKGKFGN	AURKB	76	Q96GD4
RPLGKGKFGNVYLAR	AURKB	81	Q96GD4
FLRKPGGNLGKVYQP	USP53	6	Q70EK8
KELPGKFLLGYQPRG	SUPT6H	1466	Q7KZ85
YDPGYKVKQRLGGGR	ZNF428	61	Q96B54
TYLKGRLLGKGGFAR	PLK3	61	Q9H4B4
QKGTGARPYTGKVGA	AARS1	271	P49588
KGRKVPRHFLVSGGY	THEMIS2	306	Q5TEJ8
PYLAGGDARGKKLPN	SOGA1	941	O94964
YFGAKLHRPKIIGAG	SLCO1C1	101	Q9NYB5
GGPKDFGAGLKYNSR	ST14	11	Q9Y5Y6
AAKRQDGGLFKGPPY	TCF7L2	86	Q9NQB0
GKAALVGIYGRKGLP	TENM4	471	Q6N022
LIGFFGKGYGKNKEP	SLC12A3	491	P55017
GKGYGKNKEPVRGYL	SLC12A3	496	P55017
YIGKGGLARHFKLNP	ZNF839	206	A8K0R7
QGVRGYPTLKLFKPG	TXNDC5	131	Q8NBS9
RYCRGKVLGKGGFAK	PLK2	81	Q9NYY3
GGCGRVGYLKKAFNL	PTCD1	181	O75127
LLQKMGYVPGRGLGK	TFIP11	156	Q9UBB9
GPKVRDGPGKYQLFA	USP5	791	P45974
LGKKIGSGGFGLIYL	VRK2	31	Q86Y07
PGGGKRKGKAQYVLA	THUMPD1	11	Q9NXG2
KPPKRRGGGKILGYF	MYOM3	721	Q5VTT5
KAFEYGVKQGRQGKG	PCSK1	286	P29120