Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN10A SCN11A SCN1A SCN2A SCN3A

1.81e-0926415GO:0005248
GeneOntologyMolecularFunctionsodium channel activity

SCN10A SCN11A SCN1A SCN2A SCN3A

6.86e-0852415GO:0005272
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN2A SCN3A

2.88e-0614413GO:0031402
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

SCN10A SCN1A SCN2A

5.36e-0617413GO:0099508
GeneOntologyMolecularFunctionchromatin binding

NUCKS1 KMT2A H1-8 CHD6 TAF1 CTCF TAF1L CDCA5 POLR3G

1.50e-05739419GO:0003682
GeneOntologyMolecularFunctionalkali metal ion binding

SCN1A SCN2A SCN3A

2.02e-0526413GO:0031420
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SCN10A SCN11A SCN1A SCN2A SCN3A

2.54e-05171415GO:0015081
GeneOntologyMolecularFunctionlysine-acetylated histone binding

KMT2A TAF1 TAF1L

3.14e-0530413GO:0070577
GeneOntologyMolecularFunctionacetylation-dependent protein binding

KMT2A TAF1 TAF1L

3.47e-0531413GO:0140033
GeneOntologyMolecularFunctionH3K27me3 modified histone binding

TAF1 TAF1L

4.10e-055412GO:0061628
GeneOntologyMolecularFunctionhistone modifying activity

USP36 PHF2 KMT2A TAF1 TAF1L

1.02e-04229415GO:0140993
GeneOntologyMolecularFunctionRNA polymerase I general transcription initiation factor activity

TAF1 TAF1L

1.47e-049412GO:0001181
GeneOntologyMolecularFunctionhistone binding

PHF2 KMT2A CHD6 TAF1 TAF1L

2.01e-04265415GO:0042393
GeneOntologyMolecularFunctionmonoatomic ion channel activity

SCN10A SCN11A SCN1A SCN2A SCN3A GABRA1

3.25e-04459416GO:0005216
GeneOntologyMolecularFunctionbasal RNA polymerase II transcription machinery binding

TAF1 TAF1L CTR9

3.36e-0466413GO:0001099
GeneOntologyMolecularFunctionbasal transcription machinery binding

TAF1 TAF1L CTR9

3.36e-0466413GO:0001098
GeneOntologyMolecularFunctionmonoatomic cation channel activity

SCN10A SCN11A SCN1A SCN2A SCN3A

6.55e-04343415GO:0005261
GeneOntologyMolecularFunctionchannel activity

SCN10A SCN11A SCN1A SCN2A SCN3A GABRA1

6.60e-04525416GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

SCN10A SCN11A SCN1A SCN2A SCN3A GABRA1

6.67e-04526416GO:0022803
GeneOntologyMolecularFunctionmethylated histone binding

PHF2 TAF1 TAF1L

7.31e-0486413GO:0035064
GeneOntologyMolecularFunctiontranscription factor binding

NUCKS1 KMT2A TACC2 CHD6 TAF1 CTCF TAF1L

7.74e-04753417GO:0008134
GeneOntologyMolecularFunctionmethylation-dependent protein binding

PHF2 TAF1 TAF1L

7.81e-0488413GO:0140034
GeneOntologyMolecularFunctionmodification-dependent protein binding

PHF2 KMT2A TAF1 TAF1L

8.26e-04206414GO:0140030
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

NUCKS1 KMT2A TACC2 TAF1 CTCF TAF1L

1.13e-03582416GO:0140297
GeneOntologyMolecularFunctionRNA polymerase II core promoter sequence-specific DNA binding

TAF1 TAF1L

1.20e-0325412GO:0000979
GeneOntologyMolecularFunctionRNA polymerase II general transcription initiation factor binding

TAF1 TAF1L

1.40e-0327412GO:0001091
GeneOntologyMolecularFunctionactin monomer binding

MYL4 COBLL1

1.61e-0329412GO:0003785
GeneOntologyMolecularFunctionTBP-class protein binding

TAF1 TAF1L

2.09e-0333412GO:0017025
GeneOntologyMolecularFunctiontranscription regulator inhibitor activity

TAF1 TAF1L

2.48e-0336412GO:0140416
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SCN10A SCN11A SCN1A SCN2A SCN3A

2.52e-03465415GO:0046873
GeneOntologyMolecularFunctionubiquitin conjugating enzyme activity

TAF1 TAF1L

2.62e-0337412GO:0061631
GeneOntologyMolecularFunctionubiquitin-like protein conjugating enzyme activity

TAF1 TAF1L

3.52e-0343412GO:0061650
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SCN10A SCN11A SCN1A SCN2A SCN3A GABRA1

4.24e-03758416GO:0015318
GeneOntologyMolecularFunctiongated channel activity

SCN10A SCN1A SCN2A GABRA1

4.78e-03334414GO:0022836
GeneOntologyMolecularFunctionhistone acetyltransferase activity

TAF1 TAF1L

4.92e-0351412GO:0004402
GeneOntologyMolecularFunctionRNA polymerase II general transcription initiation factor activity

TAF1 TAF1L

5.11e-0352412GO:0016251
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SCN10A SCN11A SCN1A SCN2A SCN3A GABRA1

5.28e-03793416GO:0015075
GeneOntologyMolecularFunctioncore promoter sequence-specific DNA binding

TAF1 TAF1L

5.70e-0355412GO:0001046
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

TAF1 TAF1L

5.70e-0355412GO:0061733
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

SCN10A SCN1A SCN2A

6.16e-03182413GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

SCN10A SCN1A SCN2A

6.35e-03184413GO:0022832
GeneOntologyMolecularFunctionnuclear receptor binding

TACC2 TAF1 TAF1L

6.63e-03187413GO:0016922
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

TAF1 TAF1L

6.75e-0360412GO:0034212
GeneOntologyMolecularFunctiongeneral transcription initiation factor binding

TAF1 TAF1L

7.65e-0364412GO:0140296
GeneOntologyMolecularFunctiongeneral transcription initiation factor activity

TAF1 TAF1L

8.60e-0368412GO:0140223
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SCN10A SCN11A SCN1A SCN2A SCN3A

8.85e-03627415GO:0022890
GeneOntologyMolecularFunctionp53 binding

TAF1 TAF1L

1.09e-0277412GO:0002039
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SCN10A SCN11A SCN1A SCN2A SCN3A

1.12e-02664415GO:0008324
GeneOntologyMolecularFunctionN-acetyltransferase activity

TAF1 TAF1L

1.12e-0278412GO:0008080
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

TAF1 MB21D2 PDGFRL TAF1L MAP4K1 POLR3G

1.17e-02938416GO:0016772
GeneOntologyMolecularFunctionpromoter-specific chromatin binding

TAF1 TAF1L

1.26e-0283412GO:1990841
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SCN10A SCN11A SCN1A SCN2A SCN3A

5.84e-0936385GO:0086010
GeneOntologyBiologicalProcessmembrane depolarization

SCN10A KMT2A SCN11A SCN1A SCN2A SCN3A

8.52e-08121386GO:0051899
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

SCN10A SCN11A SCN1A SCN2A SCN3A

9.68e-0862385GO:0086002
GeneOntologyBiologicalProcessneuronal action potential

SCN10A SCN11A SCN1A SCN2A SCN3A

1.05e-0763385GO:0019228
GeneOntologyBiologicalProcesscardiac muscle cell action potential

SCN10A SCN11A SCN1A SCN2A SCN3A

5.35e-0787385GO:0086001
GeneOntologyBiologicalProcesscardiac muscle contraction

SCN10A SCN11A MYL4 SCN1A SCN2A SCN3A

5.73e-07167386GO:0060048
GeneOntologyBiologicalProcesscardiac muscle cell contraction

SCN10A SCN11A SCN1A SCN2A SCN3A

7.46e-0793385GO:0086003
GeneOntologyBiologicalProcesstransmission of nerve impulse

SCN10A SCN11A SCN1A SCN2A SCN3A

1.88e-06112385GO:0019226
GeneOntologyBiologicalProcessstriated muscle contraction

SCN10A SCN11A MYL4 SCN1A SCN2A SCN3A

2.64e-06217386GO:0006941
GeneOntologyBiologicalProcessactin-mediated cell contraction

SCN10A SCN11A SCN1A SCN2A SCN3A

3.49e-06127385GO:0070252
GeneOntologyBiologicalProcesschromatin organization

USP36 PHF2 NUCKS1 KMT2A H1-8 CHD6 TAF1 CTCF TAF1L CTR9

3.55e-068963810GO:0006325
GeneOntologyBiologicalProcesschromatin remodeling

USP36 PHF2 KMT2A H1-8 CHD6 TAF1 CTCF TAF1L CTR9

6.07e-06741389GO:0006338
GeneOntologyBiologicalProcessactin filament-based movement

SCN10A SCN11A SCN1A SCN2A SCN3A

8.67e-06153385GO:0030048
GeneOntologyBiologicalProcessprotein-DNA complex organization

USP36 PHF2 NUCKS1 KMT2A H1-8 CHD6 TAF1 CTCF TAF1L CTR9

9.29e-069993810GO:0071824
GeneOntologyBiologicalProcessheart contraction

SCN10A SCN11A MYL4 SCN1A SCN2A SCN3A

1.62e-05298386GO:0060047
GeneOntologyBiologicalProcessheart process

SCN10A SCN11A MYL4 SCN1A SCN2A SCN3A

1.99e-05309386GO:0003015
GeneOntologyBiologicalProcessbehavioral response to pain

SCN10A SCN11A SCN3A

2.76e-0532383GO:0048266
GeneOntologyBiologicalProcessaction potential

SCN10A SCN11A SCN1A SCN2A SCN3A

3.23e-05201385GO:0001508
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SCN10A SCN11A SCN1A SCN2A SCN3A

3.81e-05208385GO:0035725
GeneOntologyBiologicalProcessnegative regulation of heterochromatin formation

PHF2 KMT2A

4.93e-056382GO:0031452
GeneOntologyBiologicalProcessregulation of membrane potential

SCN10A KMT2A SCN11A SCN1A SCN2A SCN3A GABRA1

6.29e-05559387GO:0042391
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception of pain

SCN10A SCN11A SCN1A

6.77e-0543383GO:0062149
GeneOntologyBiologicalProcessnegative regulation of chromatin organization

PHF2 KMT2A

6.90e-057382GO:1905268
GeneOntologyBiologicalProcessmuscle contraction

SCN10A SCN11A MYL4 SCN1A SCN2A SCN3A

8.37e-05400386GO:0006936
GeneOntologyBiologicalProcessresponse to pain

SCN10A SCN11A SCN3A

1.13e-0451383GO:0048265
GeneOntologyBiologicalProcessresponse to insecticide

MAP1B SCN3A

1.18e-049382GO:0017085
GeneOntologyBiologicalProcessfacultative heterochromatin formation

PHF2 KMT2A CTCF

1.42e-0455383GO:0140718
GeneOntologyBiologicalProcesssodium ion transport

SCN10A SCN11A SCN1A SCN2A SCN3A

1.42e-04275385GO:0006814
GeneOntologyBiologicalProcessdetection of mechanical stimulus involved in sensory perception

SCN10A SCN11A SCN1A

1.58e-0457383GO:0050974
GeneOntologyBiologicalProcessepigenetic regulation of gene expression

PHF2 KMT2A H1-8 CTCF CTR9

3.31e-04330385GO:0040029
GeneOntologyBiologicalProcessdetection of mechanical stimulus

SCN10A SCN11A SCN1A

3.55e-0475383GO:0050982
GeneOntologyBiologicalProcesstranscription initiation at RNA polymerase II promoter

PHF2 KMT2A TAF1 TAF1L

3.72e-04186384GO:0006367
GeneOntologyBiologicalProcessmuscle system process

SCN10A SCN11A MYL4 SCN1A SCN2A SCN3A

4.54e-04547386GO:0003012
GeneOntologyBiologicalProcessnegative regulation of gene expression, epigenetic

PHF2 KMT2A CTCF CTR9

5.17e-04203384GO:0045814
GeneOntologyBiologicalProcessnucleolus organization

USP36 PHF2

6.79e-0421382GO:0007000
GeneOntologyBiologicalProcessDNA-templated transcription initiation

PHF2 KMT2A TAF1 TAF1L

8.39e-04231384GO:0006352
GeneOntologyBiologicalProcessregulation of heterochromatin formation

PHF2 KMT2A

8.89e-0424382GO:0031445
GeneOntologyBiologicalProcesssensory perception of pain

SCN10A SCN11A SCN1A

9.50e-04105383GO:0019233
GeneOntologyBiologicalProcessdetection of mechanical stimulus involved in sensory perception of pain

SCN11A SCN1A

1.04e-0326382GO:0050966
GeneOntologyBiologicalProcessdetection of temperature stimulus involved in sensory perception of pain

SCN10A SCN11A

1.04e-0326382GO:0050965
GeneOntologyBiologicalProcessresponse to mechanical stimulus

SCN10A SCN11A MAP1B SCN1A

1.08e-03247384GO:0009612
GeneOntologyBiologicalProcesscircadian rhythm

SCN10A KMT2A SCN11A RAI1

1.09e-03248384GO:0007623
GeneOntologyBiologicalProcessblood circulation

SCN10A SCN11A MYL4 SCN1A SCN2A SCN3A

1.10e-03648386GO:0008015
GeneOntologyBiologicalProcessactin filament-based process

SCN10A SCN11A FGD6 ARHGEF7 SCN1A SCN2A SCN3A

1.23e-03912387GO:0030029
GeneOntologyBiologicalProcessdetection of temperature stimulus involved in sensory perception

SCN10A SCN11A

1.39e-0330382GO:0050961
GeneOntologyBiologicalProcessregulation of presynaptic membrane potential

SCN10A SCN1A

1.58e-0332382GO:0099505
GeneOntologyBiologicalProcessmulticellular organismal response to stress

SCN10A SCN11A SCN3A

1.61e-03126383GO:0033555
GeneOntologyBiologicalProcessdetection of temperature stimulus

SCN10A SCN11A

1.68e-0333382GO:0016048
GeneOntologyBiologicalProcesscirculatory system process

SCN10A SCN11A MYL4 SCN1A SCN2A SCN3A

2.06e-03733386GO:0003013
GeneOntologyBiologicalProcesssensory perception of temperature stimulus

SCN10A SCN11A

2.23e-0338382GO:0050951
GeneOntologyBiologicalProcessregulation of chromatin organization

PHF2 KMT2A

2.47e-0340382GO:1902275
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN10A SCN11A SCN1A SCN2A SCN3A

1.20e-1017405GO:0001518
GeneOntologyCellularComponentsodium channel complex

SCN10A SCN11A SCN1A SCN2A SCN3A

2.27e-0929405GO:0034706
GeneOntologyCellularComponentC-fiber

SCN10A SCN11A

2.14e-054402GO:0044299
GeneOntologyCellularComponentMLL1 complex

KMT2A TAF1 TAF1L

3.10e-0532403GO:0071339
GeneOntologyCellularComponentMLL1/2 complex

KMT2A TAF1 TAF1L

3.40e-0533403GO:0044665
GeneOntologyCellularComponentnuclear DNA-directed RNA polymerase complex

TAF1 TAF1L CTR9 POLR3G

6.37e-05113404GO:0055029
GeneOntologyCellularComponentDNA-directed RNA polymerase complex

TAF1 TAF1L CTR9 POLR3G

7.05e-05116404GO:0000428
GeneOntologyCellularComponentmonoatomic ion channel complex

SCN10A SCN11A SCN1A SCN2A SCN3A GABRA1

7.67e-05378406GO:0034702
GeneOntologyCellularComponentRNA polymerase complex

TAF1 TAF1L CTR9 POLR3G

7.79e-05119404GO:0030880
GeneOntologyCellularComponentcation channel complex

SCN10A SCN11A SCN1A SCN2A SCN3A

8.21e-05235405GO:0034703
GeneOntologyCellularComponentintercalated disc

CTNNA1 SCN1A SCN2A

2.98e-0468403GO:0014704
GeneOntologyCellularComponenthistone methyltransferase complex

KMT2A TAF1 TAF1L

3.98e-0475403GO:0035097
GeneOntologyCellularComponenttransmembrane transporter complex

SCN10A SCN11A SCN1A SCN2A SCN3A GABRA1

4.44e-04523406GO:1902495
GeneOntologyCellularComponenttransporter complex

SCN10A SCN11A SCN1A SCN2A SCN3A GABRA1

5.79e-04550406GO:1990351
GeneOntologyCellularComponentRNA polymerase II, holoenzyme

TAF1 TAF1L CTR9

6.58e-0489403GO:0016591
GeneOntologyCellularComponentmain axon

MAP1B SCN1A SCN2A

6.58e-0489403GO:0044304
GeneOntologyCellularComponentnode of Ranvier

SCN1A SCN2A

6.64e-0420402GO:0033268
GeneOntologyCellularComponentcell-cell contact zone

CTNNA1 SCN1A SCN2A

7.71e-0494403GO:0044291
GeneOntologyCellularComponentmethyltransferase complex

KMT2A TAF1 TAF1L

1.15e-03108403GO:0034708
GeneOntologyCellularComponentpronucleus

TAF1 TAF1L

1.31e-0328402GO:0045120
GeneOntologyCellularComponentaxon

SCN10A SCN11A MAP1B ARHGEF7 SCN1A SCN2A SCN3A

1.36e-03891407GO:0030424
GeneOntologyCellularComponentaxon initial segment

SCN1A SCN2A

1.40e-0329402GO:0043194
GeneOntologyCellularComponentpresynaptic membrane

SCN10A SCN11A SCN1A SCN2A

1.89e-03277404GO:0042734
GeneOntologyCellularComponentplasma membrane protein complex

SCN10A SCN11A CTNNA1 SCN1A SCN2A SCN3A

3.55e-03785406GO:0098797
GeneOntologyCellularComponenttranscription factor TFIID complex

TAF1 TAF1L

3.65e-0347402GO:0005669
GeneOntologyCellularComponenttransferase complex, transferring phosphorus-containing groups

TAF1 TAF1L CTR9 POLR3G

3.76e-03335404GO:0061695
GeneOntologyCellularComponentsynaptic membrane

SCN10A SCN11A SCN1A SCN2A GABRA1

4.87e-03583405GO:0097060
GeneOntologyCellularComponentchromatin

NUCKS1 H1-8 CHD6 TAF1 TAF1L CDCA5 CTR9 HNRNPAB

6.20e-031480408GO:0000785
GeneOntologyCellularComponentsomatodendritic compartment

SCN11A MAP1B ARHGEF7 HNRNPAB SCN1A SCN3A GABRA1

8.04e-031228407GO:0036477
GeneOntologyCellularComponenttransferase complex

KMT2A TAF1 CDC27 TAF1L CTR9 POLR3G

9.45e-03963406GO:1990234
GeneOntologyCellularComponentlamellipodium

CTNNA1 FGD6 ARHGEF7

9.63e-03230403GO:0030027
GeneOntologyCellularComponentintracellular protein-containing complex

TAF1 CCT8L1P CDC27 TAF1L CTR9 POLR3G

9.87e-03972406GO:0140535
GeneOntologyCellularComponentT-tubule

SCN1A SCN2A

1.00e-0279402GO:0030315
HumanPhenoPhotosensitive myoclonic seizure

SCN1A SCN2A GABRA1

1.71e-068173HP:0001327
HumanPhenoCyanotic episode

SCN1A SCN2A GABRA1

1.71e-068173HP:0200048
HumanPhenoLimited neck range of motion

SCN1A SCN2A GABRA1

5.01e-0611173HP:0000466
HumanPhenoEpilepsia partialis continua

SCN1A SCN2A GABRA1

6.67e-0612173HP:0012847
HumanPhenoCompulsive behaviors

MAP1B CTCF SCN1A SCN2A RAI1 GABRA1

7.55e-06158176HP:0000722
HumanPhenoRestricted or repetitive behaviors or interests

KMT2A PPP2R5D MAP1B CTCF SCN1A SCN2A RAI1 GABRA1

9.37e-06368178HP:0031432
HumanPhenoPerseverative thought

KMT2A PPP2R5D MAP1B CTCF SCN1A SCN2A RAI1 GABRA1

1.12e-05377178HP:0030223
HumanPhenoShort attention span

KMT2A TAF1 MAP1B CTCF SCN1A SCN2A RAI1 SCN3A GABRA1

1.23e-05517179HP:0000736
HumanPhenoAutistic behavior

KMT2A TAF1 PPP2R5D MAP1B CTCF SCN1A SCN2A RAI1 SCN3A GABRA1

1.32e-056781710HP:0000729
HumanPhenoDisordered formal thought process

KMT2A PPP2R5D MAP1B CTCF SCN1A SCN2A RAI1 GABRA1

1.34e-05386178HP:0025769
HumanPhenoPhotosensitive tonic-clonic seizure

SCN1A SCN2A GABRA1

1.37e-0515173HP:0007207
HumanPhenoFacial tics

SCN1A SCN2A GABRA1

1.37e-0515173HP:0011468
HumanPhenoReduced attention regulation

KMT2A TAF1 MAP1B CTCF SCN1A SCN2A RAI1 SCN3A GABRA1

1.42e-05526179HP:5200044
HumanPhenoDysgenesis of the hippocampus

SCN1A SCN2A GABRA1

1.68e-0516173HP:0025101
HumanPhenoComplex febrile seizure

SCN1A SCN2A GABRA1

1.68e-0516173HP:0011172
HumanPhenoAbnormal thought pattern

KMT2A PPP2R5D MAP1B CTCF SCN1A SCN2A RAI1 GABRA1

1.88e-05404178HP:5200269
HumanPhenoFocal motor status epilepticus

SCN1A SCN2A GABRA1

2.04e-0517173HP:0032663
HumanPhenoBilateral tonic-clonic seizure with generalized onset

CTCF SCN1A SCN2A GABRA1

2.08e-0552174HP:0025190
HumanPhenoHyperactivity

KMT2A TAF1 MAP1B CTCF SCN1A SCN2A RAI1 SCN3A GABRA1

2.31e-05558179HP:0000752
HumanPhenoVisually-induced seizure

SCN1A SCN2A GABRA1

2.44e-0518173HP:0020216
HumanPhenoPes valgus

SCN1A SCN2A RAI1 GABRA1

2.80e-0556174HP:0008081
HumanPhenoDiagnostic behavioral phenotype

KMT2A TAF1 PPP2R5D MAP1B CTCF SCN1A SCN2A RAI1 SCN3A GABRA1

3.17e-057471710HP:0025783
HumanPhenoArachnoid cyst

PPP2R5D CTCF SCN1A SCN2A

3.23e-0558174HP:0100702
HumanPhenoAbnormal arachnoid mater morphology

PPP2R5D CTCF SCN1A SCN2A

3.45e-0559174HP:0100700
HumanPhenoReflex seizure

SCN1A SCN2A GABRA1

4.57e-0522173HP:0020207
HumanPhenoGeneralized tonic seizure

CTCF SCN1A SCN2A GABRA1

4.77e-0564174HP:0010818
HumanPhenoTibial torsion

SCN1A SCN2A GABRA1

5.25e-0523173HP:0100694
HumanPhenoAbnormal response to social norms

KMT2A TAF1 PPP2R5D MAP1B CTCF SCN1A SCN2A RAI1 SCN3A GABRA1

6.32e-058071710HP:5200123
HumanPhenoSocial disinhibition

KMT2A TAF1 PPP2R5D MAP1B CTCF SCN1A SCN2A RAI1 SCN3A GABRA1

6.32e-058071710HP:5200029
HumanPhenoDisinhibition

KMT2A TAF1 PPP2R5D MAP1B CTCF SCN1A SCN2A RAI1 SCN3A GABRA1

6.32e-058071710HP:0000734
HumanPhenoInappropriate behavior

KMT2A TAF1 PPP2R5D MAP1B CTCF SCN1A SCN2A RAI1 SCN3A GABRA1

6.32e-058071710HP:0000719
HumanPhenoPoor fine motor coordination

SCN1A SCN2A RAI1 GABRA1

6.43e-0569174HP:0007010
HumanPhenoFocal hemiclonic seizure

SCN1A SCN2A GABRA1

6.79e-0525173HP:0006813
HumanPhenoSimple febrile seizure

SCN1A SCN2A SCN3A

8.60e-0527173HP:0011171
HumanPhenoLimited knee extension

SCN1A SCN2A GABRA1

8.60e-0527173HP:0003066
HumanPhenoStatus epilepticus without prominent motor symptoms

SCN1A SCN2A GABRA1

8.60e-0527173HP:0031475
HumanPhenoImpulsivity

SCN1A SCN2A RAI1 SCN3A GABRA1

9.32e-05149175HP:0100710
HumanPhenoFocal aware seizure

SCN1A SCN2A GABRA1

9.61e-0528173HP:0002349
HumanPhenoAllodynia

SCN10A SCN11A

1.04e-045172HP:0012533
HumanPhenoStatus epilepticus with prominent motor symptoms

SCN1A SCN2A GABRA1

1.07e-0429173HP:0032658
HumanPhenoAggressive behavior

KMT2A PPP2R5D CTCF SCN1A SCN2A RAI1 SCN3A GABRA1

1.12e-04516178HP:0000718
HumanPhenoAbnormal aggressive, impulsive or violent behavior

KMT2A PPP2R5D CTCF SCN1A SCN2A RAI1 SCN3A GABRA1

1.12e-04516178HP:0006919
HumanPhenoProgressive gait ataxia

SCN1A SCN2A GABRA1

1.19e-0430173HP:0007240
HumanPhenoProgressive ataxia

SCN1A SCN2A GABRA1

1.19e-0430173HP:0001329
HumanPhenoClonic seizure

SCN1A SCN2A SCN3A GABRA1

1.21e-0481174HP:0020221
HumanPhenoAbnormally increased volition

KMT2A TAF1 PPP2R5D MAP1B CTCF SCN1A SCN2A RAI1 SCN3A GABRA1

1.22e-048691710HP:5200263
HumanPhenoProminent forehead

KMT2A TAF1 PPP2R5D CTCF SCN1A RAI1

1.31e-04261176HP:0011220
HumanPhenoCogwheel rigidity

SCN1A SCN2A GABRA1

1.44e-0432173HP:0002396
HumanPhenoPoor motor coordination

SCN1A SCN2A RAI1 GABRA1

1.46e-0485174HP:0002275
HumanPhenoHypoplastic philtrum

MAP1B CTCF

1.56e-046172HP:0005326
HumanPhenoObsessive-compulsive trait

SCN1A SCN2A GABRA1

1.58e-0433173HP:0008770
HumanPhenoGeneralized clonic seizure

SCN1A SCN2A GABRA1

1.73e-0434173HP:0011169
HumanPhenoAbnormal social development

KMT2A TAF1 PPP2R5D MAP1B CTCF SCN1A SCN2A RAI1 SCN3A GABRA1

1.79e-049081710HP:0025732
HumanPhenoLimitation of knee mobility

SCN1A SCN2A GABRA1

1.89e-0435173HP:0010501
HumanPhenoMotor stereotypy

KMT2A PPP2R5D CTCF SCN1A RAI1 GABRA1

1.93e-04280176HP:0000733
HumanPhenoLimitation of neck motion

SCN1A SCN2A GABRA1

2.06e-0436173HP:0005986
HumanPhenoDisturbance of facial expression

SCN1A SCN2A GABRA1

2.06e-0436173HP:0005324
HumanPhenoAbnormal neck physiology

SCN1A SCN2A GABRA1

2.06e-0436173HP:0025669
HumanPhenoAttention deficit hyperactivity disorder

TAF1 MAP1B CTCF SCN1A RAI1 SCN3A GABRA1

2.08e-04413177HP:0007018
HumanPhenoAbnormal temper tantrums

PPP2R5D CTCF RAI1

2.24e-0437173HP:0025160
HumanPhenoFocal clonic seizure

SCN1A SCN2A GABRA1

3.27e-0442173HP:0002266
HumanPhenoSynophrys

KMT2A TAF1 MAP1B CTCF RAI1

3.32e-04195175HP:0000664
HumanPhenoOral-pharyngeal dysphagia

TAF1 COBLL1 RAI1

4.02e-0445173HP:0200136
HumanPhenoFacial hypertrichosis

KMT2A TAF1 MAP1B CTCF RAI1

4.28e-04206175HP:0002219
HumanPhenoAtypical absence seizure

SCN1A SCN2A GABRA1

4.29e-0446173HP:0007270
HumanPhenoAbnormality of upper lip vermillion

KMT2A TAF1 PPP2R5D MAP1B CTCF SCN1A RAI1

4.30e-04464177HP:0011339
HumanPhenoAbnormality of pain sensation

SCN10A SCN11A SCN1A RAI1

4.37e-04113174HP:0010832
HumanPhenoErythromelalgia

SCN10A SCN11A

4.64e-0410172HP:0032147
HumanPhenoBradykinesia

TAF1 SCN1A SCN2A GABRA1

4.83e-04116174HP:0002067
HumanPhenoAbnormal hippocampus morphology

SCN1A SCN2A GABRA1

4.87e-0448173HP:0025100
HumanPhenoProminent digit pad

KMT2A MAP1B CTCF

4.87e-0448173HP:0011298
HumanPhenoRigidity

TAF1 SCN1A SCN2A SCN3A GABRA1

5.11e-04214175HP:0002063
HumanPhenoAbnormal morphology of the limbic system

SCN1A SCN2A GABRA1

5.17e-0449173HP:0007343
HumanPhenoEpileptic encephalopathy

SCN1A SCN2A SCN3A GABRA1

5.33e-04119174HP:0200134
HumanPhenoReduced impulse control

KMT2A TAF1 PPP2R5D MAP1B CTCF SCN1A SCN2A RAI1 SCN3A GABRA1

5.37e-0410321710HP:5200045
HumanPhenoThin upper lip vermilion

KMT2A TAF1 PPP2R5D CTCF SCN1A RAI1

5.48e-04339176HP:0000219
HumanPhenoThin lips

KMT2A TAF1 PPP2R5D CTCF SCN1A RAI1

5.48e-04339176HP:0000213
HumanPhenoMaladaptive fear-related cognitions

KMT2A TAF1 CTCF SCN1A SCN2A RAI1 GABRA1

5.51e-04483177HP:5200230
HumanPhenoAnxiety

KMT2A TAF1 CTCF SCN1A SCN2A RAI1 GABRA1

5.51e-04483177HP:0000739
HumanPhenoBroad chin

TAF1 CTCF

5.67e-0411172HP:0011822
HumanPhenoFocal-onset seizure

PPP2R5D MAP1B SCN1A SCN2A SCN3A GABRA1

6.12e-04346176HP:0007359
HumanPhenoDecreased/absent ankle reflexes

SCN10A SCN11A RAI1

6.53e-0453173HP:0200101
HumanPhenoFocal impaired awareness seizure

SCN1A SCN2A SCN3A GABRA1

6.62e-04126174HP:0002384
HumanPhenoFocal automatism seizure

SCN1A SCN2A

6.78e-0412172HP:0032898
HumanPhenoMedial flaring of the eyebrow

KMT2A TAF1 MAP1B CTCF RAI1

6.84e-04228175HP:0010747
HumanPhenoGeneralized cerebral atrophy/hypoplasia

SCN1A SCN2A

8.00e-0413172HP:0007058
HumanPhenoPes planus

KMT2A CTCF SCN1A SCN2A RAI1 GABRA1

8.15e-04365176HP:0001763
HumanPhenoAbnormal judgment

KMT2A TAF1 CTCF SCN1A SCN2A RAI1 GABRA1

8.26e-04516177HP:5200401
HumanPhenoMyoclonic absence seizure

SCN1A GABRA1

9.32e-0414172HP:0011150
HumanPhenoParkinsonism

TAF1 SCN1A SCN2A GABRA1

9.33e-04138174HP:0001300
HumanPhenoTonic seizure

CTCF SCN1A SCN2A GABRA1

9.84e-04140174HP:0032792
HumanPhenoDialeptic seizure

SCN1A SCN2A RAI1 SCN3A GABRA1

1.06e-03251175HP:0011146
HumanPhenoAbnormal fear-induced behavior

KMT2A TAF1 CTCF SCN1A SCN2A RAI1 GABRA1

1.06e-03538177HP:0100852
HumanPhenoAortopulmonary collateral arteries

SCN1A SCN2A

1.07e-0315172HP:0031834
HumanPhenoInfection-related seizure

SCN1A SCN2A SCN3A GABRA1

1.12e-03145174HP:0032892
HumanPhenoSeizure precipitated by febrile infection

SCN1A SCN2A SCN3A GABRA1

1.12e-03145174HP:0032894
HumanPhenoFebrile seizure (within the age range of 3 months to 6 years)

SCN1A SCN2A SCN3A GABRA1

1.12e-03145174HP:0002373
HumanPhenoAbsence seizures with special features

SCN1A GABRA1

1.22e-0316172HP:0011148
HumanPhenoMultifocal epileptiform discharges

SCN1A SCN2A GABRA1

1.24e-0366173HP:0010841
HumanPhenoImpairment in personality functioning

KMT2A TAF1 PPP2R5D MAP1B CTCF SCN1A SCN2A RAI1 SCN3A GABRA1

1.25e-0311411710HP:0031466
MousePhenoabnormal nervous system electrophysiology

SCN10A SCN11A MAP1B CTCF SCN1A SCN2A RAI1

1.17e-05329347MP:0002272
MousePhenoembryonic lethality prior to organogenesis

USP36 KMT2A DIDO1 CTNNA1 SRBD1 MAP1B CTCF ARHGEF7 CDCA5 CTR9 RAI1 POLR3G

1.44e-0512043412MP:0013292
MousePhenoembryonic lethality prior to tooth bud stage

USP36 KMT2A DIDO1 CTNNA1 SRBD1 MAP1B CTCF ARHGEF7 CDCA5 CTR9 RAI1 POLR3G

5.79e-0513833412MP:0013293
MousePhenoabnormal posture

SCN10A KMT2A MAP1B SCN1A GABRA1

2.81e-04243345MP:0001504
MousePhenoabnormal action potential

SCN10A SCN11A SCN1A SCN2A

2.91e-04133344MP:0005402
MousePhenodecreased thermal nociceptive threshold

SCN10A SCN11A PPP2R5D

3.00e-0454343MP:0003998
DomainNa_channel_asu

SCN10A SCN11A SCN1A SCN2A SCN3A

8.69e-1210405IPR001696
DomainNa_trans_assoc

SCN10A SCN11A SCN1A SCN2A SCN3A

8.69e-1210405IPR010526
DomainNa_trans_assoc

SCN10A SCN11A SCN1A SCN2A SCN3A

8.69e-1210405PF06512
DomainChannel_four-helix_dom

SCN10A SCN11A SCN1A SCN2A SCN3A

1.34e-0757405IPR027359
Domain-

SCN10A SCN11A SCN1A SCN2A SCN3A

1.34e-07574051.20.120.350
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A

1.81e-076403PF11933
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A

1.81e-076403IPR024583
DomainIon_trans_dom

SCN10A SCN11A SCN1A SCN2A SCN3A

4.30e-06114405IPR005821
DomainIon_trans

SCN10A SCN11A SCN1A SCN2A SCN3A

4.30e-06114405PF00520
DomainTAF_II_230-bd

TAF1 TAF1L

4.47e-062402IPR009067
DomainDUF3591

TAF1 TAF1L

4.47e-062402PF12157
DomainTFIID_sub1_DUF3591

TAF1 TAF1L

4.47e-062402IPR022591
Domain-

TAF1 TAF1L

4.47e-0624021.10.1100.10
DomainTBP-binding

TAF1 TAF1L

4.47e-062402PF09247
DomainTAF1_animal

TAF1 TAF1L

4.47e-062402IPR011177
DomainPHD

PHF2 KMT2A DIDO1 RAI1

3.86e-0589404SM00249
DomainIQ_motif_EF-hand-BS

SCN10A SCN1A SCN2A SCN3A

4.04e-0590404IPR000048
DomainZnf_PHD

PHF2 KMT2A DIDO1 RAI1

4.21e-0591404IPR001965
DomainIQ

SCN10A SCN1A SCN2A SCN3A

4.59e-0593404PS50096
DomainZF_PHD_2

PHF2 KMT2A DIDO1 RAI1

4.99e-0595404PS50016
DomainZF_PHD_1

PHF2 KMT2A DIDO1 RAI1

5.20e-0596404PS01359
DomainBROMODOMAIN_2

KMT2A TAF1 TAF1L

9.17e-0541403PS50014
DomainBROMO

KMT2A TAF1 TAF1L

9.86e-0542403SM00297
DomainBromodomain

KMT2A TAF1 TAF1L

9.86e-0542403IPR001487
Domain-

KMT2A TAF1 TAF1L

9.86e-05424031.20.920.10
DomainZnf_FYVE_PHD

PHF2 KMT2A DIDO1 FGD6

2.70e-04147404IPR011011
DomainIQ

SCN10A SCN1A SCN3A

4.70e-0471403PF00612
DomainPHD

PHF2 KMT2A DIDO1

5.52e-0475403PF00628
DomainZnf_PHD-finger

PHF2 KMT2A DIDO1

6.43e-0479403IPR019787
DomainIQ

SCN1A SCN2A SCN3A

6.92e-0481403SM00015
DomainEPHD

KMT2A RAI1

1.01e-0322402PS51805
DomainBromodomain_CS

TAF1 TAF1L

1.41e-0326402IPR018359
DomainBROMODOMAIN_1

TAF1 TAF1L

2.84e-0337402PS00633
DomainBromodomain

TAF1 TAF1L

2.99e-0338402PF00439
DomainTPR_8

CDC27 CTR9

5.75e-0353402PF13181
DomainIg_I-set

IGSF22 IGFN1 PDGFRL

7.77e-03190403IPR013098
DomainI-set

IGSF22 IGFN1 PDGFRL

7.77e-03190403PF07679
DomainZinc_finger_PHD-type_CS

PHF2 DIDO1

8.54e-0365402IPR019786
DomainRhoGEF

FGD6 ARHGEF7

9.32e-0368402SM00325
DomainDH_2

FGD6 ARHGEF7

9.85e-0370402PS50010
DomainRhoGEF

FGD6 ARHGEF7

9.85e-0370402PF00621
DomainDH-domain

FGD6 ARHGEF7

1.01e-0271402IPR000219
Domain-

FGD6 ARHGEF7

1.01e-02714021.20.900.10
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN10A SCN11A SCN1A SCN2A SCN3A

2.86e-0931275M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN10A SCN11A SCN1A SCN2A SCN3A

3.39e-0932275M27455
PathwayREACTOME_MUSCLE_CONTRACTION

SCN10A SCN11A MYL4 SCN1A SCN2A SCN3A

1.90e-06203276M5485
PathwayREACTOME_L1CAM_INTERACTIONS

SCN10A SCN11A SCN1A SCN2A SCN3A

2.98e-06121275M872
PathwayREACTOME_CARDIAC_CONDUCTION

SCN10A SCN11A SCN1A SCN2A SCN3A

4.24e-06130275M27454
PathwayWP_DRAVET_SYNDROME

SCN1A SCN2A SCN3A

1.99e-0528273M45519
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

SCN10A SCN11A SCN1A SCN2A SCN3A GABRA1

5.57e-05367276M48346
PathwayKEGG_MEDICUS_REFERENCE_ESTABLISHMENT_OF_COHESION

CTCF CDCA5

7.38e-057272M47869
PathwayWP_MECP2_AND_ASSOCIATED_RETT_SYNDROME

TAF1 CTCF TAF1L

9.00e-0546273MM15949
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

SCN10A KMT2A SCN11A H1-8 CTNNA1 CTCF ARHGEF7 SCN1A SCN2A SCN3A

1.89e-0414322710M509
PathwayWP_DRAVET_SYNDROME_SCN1AA1783V_POINT_MUTATION_MODEL

SCN1A SCN3A GABRA1

3.56e-0473273MM16641
PathwayKEGG_MEDICUS_REFERENCE_COHESIN_DISSOCIATION_IN_PROPHASE

PPP2R5D CDCA5

4.17e-0416272M47870
PathwayREACTOME_RNA_POLYMERASE_II_PRE_TRANSCRIPTION_EVENTS

TAF1 TAF1L CTR9

4.84e-0481273M865
PathwayREACTOME_RNA_POLYMERASE_II_PRE_TRANSCRIPTION_EVENTS

TAF1 TAF1L CTR9

5.20e-0483273MM15314
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

SCN10A SCN11A ARHGEF7 SCN1A SCN2A SCN3A

6.38e-04575276M29853
PathwayPID_LIS1_PATHWAY

PPP2R5D MAP1B

1.29e-0328272M163
PathwayPID_AURORA_A_PATHWAY

PPP2R5D ARHGEF7

1.59e-0331272M242
PathwayWP_COHESIN_COMPLEX_CORNELIA_DE_LANGE_SYNDROME

PPP2R5D CDCA5

1.91e-0334272M42555
PathwayKEGG_BASAL_TRANSCRIPTION_FACTORS

TAF1 TAF1L

2.02e-0335272M4864
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN10A SCN11A SCN1A SCN2A SCN3A

2.52e-13942516382098
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

USP36 PHF2 KMT2A DIDO1 CHD6 QSER1 SRBD1 CDC27 CTCF TAF1L CDCA5 CTR9 HNRNPAB RAI1 KNOP1

1.28e-111294421530804502
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN10A SCN1A SCN2A SCN3A

2.75e-11642423652591
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

USP36 PHF2 KMT2A DIDO1 TAF1 QSER1 MAP1B CTCF TAF1L CDCA5 HNRNPAB RAI1 KNOP1

5.61e-11954421336373674
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN10A SCN1A SCN2A SCN3A

1.30e-091342415123669
Pubmed

Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

SCN1A SCN2A SCN3A

1.64e-09342312610651
Pubmed

SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.

SCN1A SCN2A SCN3A

1.64e-09342323859570
Pubmed

Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.

SCN1A SCN2A SCN3A

1.64e-09342314973256
Pubmed

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

SCN1A SCN2A SCN3A

1.64e-09342318784617
Pubmed

Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.

SCN1A SCN2A SCN3A

1.64e-09342317544618
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

PHF2 KMT2A DIDO1 CHD6 TAF1 QSER1 SRBD1 CDC27 RAI1 KNOP1

2.20e-09608421036089195
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN2A SCN3A

6.54e-09442317537961
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN2A SCN3A

6.54e-09442335031483
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN2A SCN3A

6.54e-09442329578003
Pubmed

Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.

SCN1A SCN2A SCN3A

6.54e-09442335801810
Pubmed

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

SCN1A SCN2A SCN3A

6.54e-0944238974318
Pubmed

Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.

SCN1A SCN2A SCN3A

1.63e-0854231679748
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

SCN1A SCN2A SCN3A

1.63e-0854238812438
Pubmed

Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.

SCN1A SCN2A SCN3A

1.63e-08542324337656
Pubmed

An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways.

SCN10A SCN11A SCN3A

3.27e-08642323711479
Pubmed

Pain without nociceptors? Nav1.7-independent pain mechanisms.

SCN10A SCN11A SCN3A

5.71e-08742324440715
Pubmed

Significant determinants of mouse pain behaviour.

SCN10A SCN11A SCN3A

9.13e-08842325101983
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN2A SCN3A

1.37e-07942315746173
Pubmed

Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.

SCN1A SCN2A SCN3A

3.58e-07124238169823
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1A SCN2A SCN3A

3.58e-071242330175250
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

KMT2A DIDO1 TAF1 MAP1B CTCF HNRNPAB RAI1

4.35e-0739442727248496
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

USP36 DIDO1 QSER1 MAP1B CTCF KNOP1 WDR46

5.68e-0741042726949251
Pubmed

Confirmation of quantitative trait loci for alcohol preference in mice.

SCN1A SCN2A SCN3A

7.38e-07154239726281
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

KMT2A SCN11A CHD6 SRBD1 ARMC3 MAP1B CDC27 CTR9 HNRNPAB RAI1 KNOP1

7.83e-071442421135575683
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

PHF2 KMT2A CHD6 SRBD1 MAP1B ARHGEF7 CDCA5 RAI1

9.07e-0764542825281560
Pubmed

The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.

KMT2A DIDO1 SRBD1 CDC27 CTR9 RAI1

1.08e-0628142624163370
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

USP36 PHF2 KMT2A DIDO1 CHD6 SRBD1 CDC27 CTCF TAF1L CTR9 KNOP1

1.13e-061497421131527615
Pubmed

The contribution of de novo coding mutations to autism spectrum disorder.

PHF2 PPP2R5D CTCF

1.32e-061842325363768
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

USP36 NUCKS1 KMT2A DIDO1 TACC2 MAP1B CTCF HNRNPAB KNOP1

1.41e-0693442933916271
Pubmed

Sodium Channel Nav1.8 Underlies TTX-Resistant Axonal Action Potential Conduction in Somatosensory C-Fibers of Distal Cutaneous Nerves.

SCN10A SCN11A

1.42e-06242228450535
Pubmed

Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders.

TAF1 TAF1L

1.42e-06242238804708
Pubmed

Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.

SCN1A SCN2A

1.42e-06242229649454
Pubmed

Assessing acute myeloid leukemia susceptibility in rearrangement-driven patients by DNA breakage at topoisomerase II and CCCTC-binding factor/cohesin binding sites.

KMT2A CTCF

1.42e-06242234405474
Pubmed

Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.

SCN2A SCN3A

1.42e-06242220346423
Pubmed

Heat-resistant action potentials require TTX-resistant sodium channels NaV1.8 and NaV1.9.

SCN10A SCN11A

1.42e-06242229970412
Pubmed

Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.

SCN1A SCN2A

1.42e-06242226311622
Pubmed

Exploring the role of nociceptor-specific sodium channels in pain transmission using Nav1.8 and Nav1.9 knockout mice.

SCN10A SCN11A

1.42e-06242219931571
Pubmed

TAFII250, Egr-1, and D-type cyclin expression in mice and neonatal rat cardiomyocytes treated with doxorubicin.

TAF1 TAF1L

1.42e-06242210070062
Pubmed

Tetrodotoxin-resistant voltage-gated sodium channels Na(v)1.8 and Na(v)1.9 are expressed in the retina.

SCN10A SCN11A

1.42e-06242218399542
Pubmed

Correlation of Nav1.8 and Nav1.9 sodium channel expression with neuropathic pain in human subjects with lingual nerve neuromas.

SCN10A SCN11A

1.42e-06242224144460
Pubmed

Sustained expression of a neuron-specific isoform of the Taf1 gene in development stages and aging in mice.

TAF1 TAF1L

1.42e-06242222842574
Pubmed

Contributions of NaV1.8 and NaV1.9 to excitability in human induced pluripotent stem-cell derived somatosensory neurons.

SCN10A SCN11A

1.42e-06242234930944
Pubmed

Dissecting the role of sodium currents in visceral sensory neurons in a model of chronic hyperexcitability using Nav1.8 and Nav1.9 null mice.

SCN10A SCN11A

1.42e-06242216857712
Pubmed

Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.

SCN1A SCN2A

1.42e-06242210827969
Pubmed

Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.

SCN1A SCN2A

1.42e-06242215249644
Pubmed

Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.

SCN1A SCN3A

1.42e-06242227690330
Pubmed

Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.

SCN1A SCN2A

1.42e-06242219694741
Pubmed

Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.

SCN2A SCN3A

1.42e-06242211245985
Pubmed

Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.

TAF1 TAF1L

1.42e-06242227571988
Pubmed

Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms.

TAF1 TAF1L

1.42e-06242234403156
Pubmed

The Nav1.9 channel is a key determinant of cold pain sensation and cold allodynia.

SCN10A SCN11A

1.42e-06242225959819
Pubmed

Maladaptive activation of Nav1.9 channels by nitric oxide causes triptan-induced medication overuse headache.

SCN10A SCN11A

1.42e-06242231534133
Pubmed

The developmental changes of Na(v)1.1 and Na(v)1.2 expression in the human hippocampus and temporal lobe.

SCN1A SCN2A

1.42e-06242221377452
Pubmed

Differential expression of two sodium channel subtypes in human brain.

SCN1A SCN2A

1.42e-0624221317301
Pubmed

Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.

SCN1A SCN3A

1.42e-06242223965409
Pubmed

Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.

SCN2A SCN3A

1.42e-06242223016767
Pubmed

Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.

SCN2A SCN3A

1.42e-06242227153334
Pubmed

Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.

SCN1A SCN2A

1.42e-06242233096315
Pubmed

Evaluating the Role of Genetic Variants on first-line antiepileptic drug response in North India: Significance of SCN1A and GABRA1 Gene Variants in Phenytoin Monotherapy and its Serum Drug Levels.

SCN1A GABRA1

1.42e-06242227245092
Pubmed

Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.

SCN1A SCN3A

1.42e-06242224990319
Pubmed

Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.

SCN1A SCN2A

1.42e-06242231439038
Pubmed

SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.

SCN1A SCN2A

1.42e-06242230693367
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

NUCKS1 DIDO1 TACC2 CDCA5 CTR9 HNRNPAB COBLL1

2.21e-0650342716964243
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

PHF2 KMT2A DIDO1 CHD6 MYL4 CDC27 CTR9 HNRNPAB KNOP1 WDR46

2.87e-061318421030463901
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

USP36 MAP1B CTCF RAI1 KNOP1 WDR46

3.78e-0634942625665578
Pubmed

Voltage-gated sodium channels in taste bud cells.

SCN2A SCN3A

4.27e-06342219284629
Pubmed

Gene-to-gene interaction between sodium channel-related genes in determining the risk of antiepileptic drug resistance.

SCN1A SCN2A

4.27e-06342219270815
Pubmed

Diagnostic outcomes for genetic testing of 70 genes in 8565 patients with epilepsy and neurodevelopmental disorders.

SCN2A GABRA1

4.27e-06342229655203
Pubmed

Nav1.2 is expressed in caudal ganglionic eminence-derived disinhibitory interneurons: Mutually exclusive distributions of Nav1.1 and Nav1.2.

SCN1A SCN2A

4.27e-06342228784306
Pubmed

Identification of functional voltage-gated Na(+) channels in cultured human pulmonary artery smooth muscle cells.

SCN2A SCN3A

4.27e-06342216052353
Pubmed

Association of SCN1A, SCN2A, and UGT2B7 Polymorphisms with Responsiveness to Valproic Acid in the Treatment of Epilepsy.

SCN1A SCN2A

4.27e-06342232185219
Pubmed

Genetic Analysis of SCN11A, SCN10A, and SCN9A in Familial Episodic Pain Syndrome (FEPS) in Japan and Proposal of Clinical Diagnostic Criteria.

SCN10A SCN11A

4.27e-06342238999942
Pubmed

Clinical exome sequencing as the first-tier test for diagnosing developmental disorders covering both CNV and SNV: a Chinese cohort.

SCN1A SCN2A

4.27e-06342232005694
Pubmed

Association of SCN1A, SCN2A and ABCC2 gene polymorphisms with the response to antiepileptic drugs in Chinese Han patients with epilepsy.

SCN1A SCN2A

4.27e-06342225155934
Pubmed

TAFII55 binding to TAFII250 inhibits its acetyltransferase activity.

TAF1 TAF1L

4.27e-06342211592977
Pubmed

Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).

SCN1A SCN3A

4.27e-06342233895391
Pubmed

A disease mutation reveals a role for NaV1.9 in acute itch.

SCN10A SCN11A

4.27e-06342230395542
Pubmed

Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.

SCN1A SCN2A

4.27e-06342217928448
Pubmed

Yield of peripheral sodium channels gene screening in pure small fibre neuropathy.

SCN10A SCN11A

4.27e-06342230554136
Pubmed

Abnormal expression of voltage-gated sodium channels Nav1.7, Nav1.3 and Nav1.8 in trigeminal neuralgia.

SCN10A SCN3A

4.27e-06342219699781
Pubmed

Regulated expression of TAF1 in 1-cell mouse embryos.

TAF1 TAF1L

4.27e-06342216822332
Pubmed

Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis.

TAF1 TAF1L

4.27e-06342212217962
Pubmed

TAF7: a possible transcription initiation check-point regulator.

TAF1 TAF1L

4.27e-06342216407123
Pubmed

Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice.

SCN10A SCN3A

4.27e-06342217052333
Pubmed

Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.

SCN1A SCN2A

4.27e-06342232845893
Pubmed

Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.

SCN1A SCN2A

4.27e-06342228518218
Pubmed

GAPDH-mediated posttranscriptional regulations of sodium channel Scn1a and Scn3a genes under seizure and ketogenic diet conditions.

SCN1A SCN3A

4.27e-06342227816501
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

USP36 KMT2A PPP2R5D CDC27 WDR46

5.43e-0621042516565220
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

PHF2 NUCKS1 KMT2A DIDO1 QSER1 CDCA5 CTR9 HNRNPAB RAI1

5.46e-06110342934189442
Pubmed

Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms.

SCN1A SCN2A

8.53e-06442226637798
Pubmed

Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.

SCN1A SCN2A

8.53e-06442221156207
Pubmed

Gene trap expression and mutational analysis for genes involved in the development of the mammalian nervous system.

CTNNA1 MAP1B

8.53e-0644229626495
Pubmed

Dorsal root ganglia isolated from Nf1+/- mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels.

SCN10A SCN1A

8.53e-06442222260870
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

KMT2A DIDO1 CTNNA1 MAP1B CTCF RAI1 WDR46

1.21e-0565342722586326
Pubmed

Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function.

SCN10A SCN11A

1.42e-05542237117223
InteractionH3C1 interactions

USP36 NUCKS1 KMT2A DIDO1 TAF1 SRBD1 CDC27 CTCF CDCA5 CTR9 HNRNPAB COBLL1 KNOP1 WDR46

1.32e-099014114int:H3C1
InteractionH2BC21 interactions

PHF2 NUCKS1 KMT2A DIDO1 QSER1 SRBD1 MAP1B CDC27 CDCA5 CTR9 MAP4K1 RAI1

8.25e-096964112int:H2BC21
InteractionH2BC8 interactions

PHF2 NUCKS1 KMT2A DIDO1 CHD6 QSER1 SRBD1 CTCF CDCA5 RAI1 KNOP1

1.37e-085764111int:H2BC8
InteractionH3C3 interactions

PHF2 KMT2A DIDO1 CHD6 TAF1 QSER1 SRBD1 CDC27 RAI1 KNOP1

4.13e-084954110int:H3C3
InteractionSMC5 interactions

USP36 PHF2 KMT2A DIDO1 TAF1 QSER1 MAP1B CTCF TAF1L CDCA5 HNRNPAB RAI1 KNOP1

4.93e-0810004113int:SMC5
InteractionZNF330 interactions

USP36 PHF2 KMT2A TAF1 SRBD1 CDC27 CTR9 RAI1 KNOP1

2.20e-07446419int:ZNF330
InteractionPOLR1E interactions

USP36 PHF2 KMT2A CHD6 TAF1 CTCF CTR9 KNOP1

4.43e-07350418int:POLR1E
InteractionCENPA interactions

USP36 PHF2 KMT2A CHD6 TAF1 SRBD1 RAI1 KNOP1

7.76e-07377418int:CENPA
InteractionSCN10A interactions

SCN10A SCN11A SCN1A

1.28e-0611413int:SCN10A
InteractionH2BC3 interactions

USP36 KMT2A DIDO1 MAP1B CDC27 HNRNPAB RAI1 KNOP1

1.35e-06406418int:H2BC3
InteractionH3-3A interactions

PHF2 KMT2A DIDO1 TAF1 QSER1 SRBD1 CDC27 CDCA5 RAI1 KNOP1

1.87e-067494110int:H3-3A
InteractionSCN11A interactions

SCN10A SCN11A SCN1A

3.50e-0615413int:SCN11A
InteractionCFAP141 interactions

USP36 DIDO1 KNOP1 WDR46

4.66e-0655414int:CFAP141
InteractionMKI67 interactions

USP36 KMT2A DIDO1 QSER1 MB21D2 MAP1B CTCF KNOP1 WDR46

4.85e-06648419int:MKI67
InteractionPOLR1G interactions

USP36 PHF2 KMT2A TAF1 CTCF CTR9 RAI1 KNOP1

5.36e-06489418int:POLR1G
InteractionANAPC15 interactions

USP36 DIDO1 CDC27 KNOP1 WDR46

5.96e-06128415int:ANAPC15
InteractionPARP1 interactions

USP36 PHF2 NUCKS1 DIDO1 CHD6 CTNNA1 SRBD1 CTCF CTR9 HNRNPAB RAI1 KNOP1

7.66e-0613164112int:PARP1
InteractionH2AZ1 interactions

USP36 PHF2 NUCKS1 SRBD1 CDC27 CTCF RAI1

8.88e-06371417int:H2AZ1
InteractionLLPH interactions

USP36 H1-8 CTCF KNOP1 WDR46

8.91e-06139415int:LLPH
InteractionASF1A interactions

PHF2 KMT2A CHD6 TAF1 QSER1 RAI1

1.05e-05249416int:ASF1A
InteractionTERF2IP interactions

NUCKS1 KMT2A DIDO1 TAF1 QSER1 CTCF RAI1 KNOP1

1.30e-05552418int:TERF2IP
InteractionCACNA1D interactions

SCN10A SCN11A SCN1A

1.54e-0524413int:CACNA1D
InteractionHECTD1 interactions

DIDO1 TACC2 TAF1 PPP2R5D MB21D2 SRBD1 MAP1B CDC27 HNRNPAB KNOP1

2.07e-059844110int:HECTD1
InteractionRPL27 interactions

USP36 H1-8 MAP1B CTCF CTR9 RAI1 KNOP1

2.34e-05431417int:RPL27
InteractionSCN1A interactions

SCN10A SCN11A SCN1A

2.75e-0529413int:SCN1A
InteractionMEN1 interactions

KMT2A DIDO1 TAF1 PPP2R5D QSER1 SRBD1 CTCF HNRNPAB KNOP1 WDR46

3.04e-0510294110int:MEN1
InteractionLINC02910 interactions

USP36 DIDO1 KNOP1 WDR46

4.11e-0595414int:LINC02910
InteractionHECW2 interactions

KMT2A DIDO1 SRBD1 CDC27 CTR9 RAI1

4.46e-05322416int:HECW2
InteractionDDX23 interactions

USP36 PHF2 TAF1 MAP1B CTR9 GABRA1 KNOP1

4.64e-05480417int:DDX23
InteractionGAGE2E interactions

USP36 DIDO1 WDR46

5.33e-0536413int:GAGE2E
InteractionFEV interactions

KMT2A CHD6 TAF1 QSER1 CTCF

5.51e-05203415int:FEV
InteractionBRD3 interactions

PHF2 KMT2A TAF1 CDC27 CTCF RAI1 KNOP1

5.56e-05494417int:BRD3
InteractionCACNA1B interactions

SCN11A MAP1B SCN1A

5.79e-0537413int:CACNA1B
InteractionNUCKS1 interactions

NUCKS1 KMT2A DIDO1 CDC27 RAI1

8.06e-05220415int:NUCKS1
InteractionXRCC6 interactions

USP36 PHF2 KMT2A DIDO1 CTNNA1 TAF1 MAP1B TAF1L CDCA5

8.29e-05928419int:XRCC6
InteractionRPL32 interactions

USP36 NUCKS1 H1-8 CTCF MAP4K1 WDR46

8.52e-05362416int:RPL32
InteractionCTR9 interactions

KMT2A TACC2 PPP2R5D FGD6 CTR9

1.06e-04233415int:CTR9
InteractionCOIL interactions

USP36 PHF2 CHD6 TAF1 SRBD1 CTR9 KNOP1

1.12e-04552417int:COIL
InteractionSCN4B interactions

SCN1A SCN2A

1.12e-048412int:SCN4B
InteractionCACNA1A interactions

SCN10A SCN11A MAP1B SCN1A

1.12e-04123414int:CACNA1A
InteractionSCN5A interactions

SCN10A SCN11A SCN1A

1.19e-0447413int:SCN5A
InteractionCHD3 interactions

USP36 KMT2A CHD6 TAF1 CTR9 HNRNPAB RAI1 KNOP1

1.21e-04757418int:CHD3
InteractionNAA40 interactions

USP36 NUCKS1 KMT2A DIDO1 TACC2 MAP1B CTCF HNRNPAB KNOP1

1.24e-04978419int:NAA40
InteractionH2AJ interactions

USP36 DIDO1 KNOP1 WDR46

1.27e-04127414int:H2AJ
InteractionAR interactions

KMT2A DIDO1 CTNNA1 TAF1 QSER1 CDC27 CTR9 HNRNPAB RAI1

1.38e-04992419int:AR
InteractionDHX40 interactions

USP36 PHF2 TAF1 CTR9 RAI1

1.44e-04249415int:DHX40
InteractionTBP interactions

KMT2A TAF1 CDC27 TAF1L POLR3G

1.55e-04253415int:TBP
InteractionPUM3 interactions

USP36 H1-8 CTCF KNOP1 WDR46

1.58e-04254415int:PUM3
InteractionFGFBP1 interactions

USP36 KMT2A CTCF KNOP1 WDR46

1.67e-04257415int:FGFBP1
InteractionRPL13A interactions

USP36 KMT2A H1-8 MAP1B CTCF HNRNPAB KNOP1

1.70e-04591417int:RPL13A
InteractionUQCR11 interactions

DIDO1 KNOP1 WDR46

1.71e-0453413int:UQCR11
InteractionRRP8 interactions

USP36 H1-8 SRBD1 KNOP1 WDR46

1.73e-04259415int:RRP8
InteractionSGO1 interactions

PPP2R5D CDCA5 CTR9 HNRNPAB

1.75e-04138414int:SGO1
InteractionANOS1 interactions

USP36 KMT2A SRBD1 KNOP1

2.01e-04143414int:ANOS1
InteractionBRD2 interactions

PHF2 TAF1 QSER1 CDC27 CTCF KNOP1

2.15e-04429416int:BRD2
InteractionRPL26L1 interactions

H1-8 SRBD1 MAP1B CTCF KNOP1 WDR46

2.20e-04431416int:RPL26L1
InteractionNUP43 interactions

USP36 PHF2 KMT2A CHD6 CTCF CDCA5 KNOP1

2.40e-04625417int:NUP43
InteractionCSNK2B interactions

PHF2 KMT2A DIDO1 PPP2R5D CTCF CTR9 MAP4K1

2.40e-04625417int:CSNK2B
InteractionRPL22 interactions

USP36 NUCKS1 H1-8 MAP1B CTCF KNOP1

2.46e-04440416int:RPL22
InteractionRCOR2 interactions

TAF1 PDGFRL CTR9

2.47e-0460413int:RCOR2
InteractionRPL18A interactions

USP36 PHF2 DIDO1 SRBD1 CTCF KNOP1

2.68e-04447416int:RPL18A
InteractionH3-4 interactions

PHF2 KMT2A DIDO1 CHD6 TAF1 HNRNPAB

2.71e-04448416int:H3-4
InteractionCTCFL interactions

USP36 CTCF WDR46

2.72e-0462413int:CTCFL
InteractionRBBP5 interactions

USP36 NUCKS1 KMT2A TAF1 CDC27

2.79e-04287415int:RBBP5
InteractionTAF4 interactions

TAF1 CDC27 TAF1L CDCA5

2.80e-04156414int:TAF4
InteractionWDR5 interactions

USP36 NUCKS1 KMT2A CTNNA1 TAF1 CDC27 CTCF CDCA5 HNRNPAB

3.01e-041101419int:WDR5
InteractionANAPC7 interactions

NUCKS1 MAP1B CDC27 RAI1

3.23e-04162414int:ANAPC7
InteractionNALCN interactions

SCN11A SCN1A

3.62e-0414412int:NALCN
InteractionNR2C2 interactions

PHF2 KMT2A DIDO1 CHD6 MYL4 CDC27 CTR9 HNRNPAB KNOP1 WDR46

3.96e-0414034110int:NR2C2
InteractionKMT2A interactions

NUCKS1 KMT2A TAF1 CDC27 CTR9

4.21e-04314415int:KMT2A
InteractionADARB1 interactions

USP36 DIDO1 CTCF HNRNPAB KNOP1 WDR46

4.33e-04489416int:ADARB1
InteractionDDB1 interactions

USP36 NUCKS1 TAF1 MAP1B MAP4K1 COBLL1 WDR46

4.63e-04697417int:DDB1
InteractionH2BC12 interactions

USP36 KMT2A DIDO1 MAP1B KNOP1

4.72e-04322415int:H2BC12
InteractionLAS1L interactions

USP36 KMT2A TAF1 CTCF

5.02e-04182414int:LAS1L
InteractionRPL36 interactions

USP36 NUCKS1 KMT2A CTCF HNRNPAB KNOP1

5.08e-04504416int:RPL36
InteractionHP1BP3 interactions

USP36 NUCKS1 H1-8 CTCF WDR46

5.20e-04329415int:HP1BP3
InteractionH1-1 interactions

H1-8 TAF1 CDC27 CTCF CTR9 KNOP1

5.24e-04507416int:H1-1
InteractionIFI16 interactions

USP36 SRBD1 MAP1B CTCF HNRNPAB KNOP1 WDR46

5.35e-04714417int:IFI16
InteractionKAT6A interactions

NUCKS1 KMT2A SRBD1 CTCF CTR9 KNOP1

5.40e-04510416int:KAT6A
InteractionRPS3 interactions

USP36 NUCKS1 H1-8 SRBD1 MAP1B CTCF HNRNPAB

5.67e-04721417int:RPS3
InteractionNUP50 interactions

KMT2A TAF1 HNRNPAB RAI1 KNOP1

6.12e-04341415int:NUP50
InteractionFBXW7 interactions

USP36 KMT2A DIDO1 CHD6 SRBD1 CTCF ARHGEF7 MAP4K1 KNOP1

6.19e-041215419int:FBXW7
InteractionCHD8 interactions

KMT2A TAF1 CDC27 CTCF

6.26e-04193414int:CHD8
InteractionRRS1 interactions

USP36 DIDO1 H1-8 KNOP1 WDR46

6.45e-04345415int:RRS1
InteractionSIRT7 interactions

KMT2A DIDO1 CTNNA1 MAP1B CTCF RAI1 WDR46

6.83e-04744417int:SIRT7
InteractionTAF5 interactions

TAF1 CDC27 TAF1L

7.11e-0486413int:TAF5
InteractionCEBPA interactions

PHF2 NUCKS1 KMT2A DIDO1 QSER1 CDCA5 CTR9 HNRNPAB RAI1

7.38e-041245419int:CEBPA
InteractionSCN9A interactions

SCN11A SCN1A

8.27e-0421412int:SCN9A
InteractionTAF1L interactions

TAF1 TAF1L

9.09e-0422412int:TAF1L
InteractionMECP2 interactions

PHF2 NUCKS1 DIDO1 CHD6 SRBD1 MAP1B ARHGEF7 HNRNPAB KNOP1

9.36e-041287419int:MECP2
InteractionKRR1 interactions

USP36 KMT2A CTCF KNOP1 WDR46

9.84e-04379415int:KRR1
InteractionRBBP4 interactions

USP36 NUCKS1 KMT2A CTCF CDCA5 RAI1

9.92e-04573416int:RBBP4
InteractionRUVBL1 interactions

USP36 KMT2A MAP1B CTCF CDCA5 CTR9

1.01e-03575416int:RUVBL1
InteractionNCL interactions

USP36 KMT2A DIDO1 CDC27 CTCF HNRNPAB WDR46

1.03e-03798417int:NCL
InteractionZNF510 interactions

CTNNA1 PDGFRL

1.08e-0324412int:ZNF510
InteractionRPL37A interactions

USP36 H1-8 CTCF KNOP1 WDR46

1.13e-03391415int:RPL37A
InteractionKLF3 interactions

KMT2A CHD6 TAF1 QSER1

1.16e-03228414int:KLF3
InteractionIQCF2 interactions

TAF1 HNRNPAB

1.18e-0325412int:IQCF2
InteractionGAR1 interactions

USP36 TAF1 CTR9 WDR46

1.24e-03232414int:GAR1
InteractionFBP2 interactions

CTNNA1 PDGFRL

1.27e-0326412int:FBP2
Cytoband2q24.3

SCN1A COBLL1 SCN2A

3.95e-07164232q24.3
CytobandEnsembl 112 genes in cytogenetic band chr2q24

SCN1A COBLL1 SCN2A SCN3A

5.76e-06127424chr2q24
Cytoband3p22.2

SCN10A SCN11A

2.23e-04244223p22.2
Cytoband1q32.1

NUCKS1 IGFN1

4.44e-031084221q32.1
GeneFamilySodium voltage-gated channel alpha subunits

SCN10A SCN11A SCN1A SCN2A SCN3A

9.26e-1392951203
GeneFamilyPHD finger proteins

PHF2 KMT2A DIDO1

3.97e-049029388
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

IGSF22 IGFN1 PDGFRL

2.14e-03161293593
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

FGD6 ARHGEF7

5.00e-0366292722
CoexpressionZHENG_CORD_BLOOD_C10_MULTILYMPHOID_PROGENITOR

USP36 FGD6 ARHGEF7 COBLL1 SCN3A

4.77e-0797425M39219
CoexpressionGSE17721_POLYIC_VS_PAM3CSK4_2H_BMDC_UP

USP36 KMT2A ARHGEF7 MAP4K1 RAI1

1.66e-05200425M3830
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#2_top-relative-expression-ranked_500

MB21D2 CDC27 FGD6 SCN1A SCN3A GABRA1

2.26e-06206406gudmap_developingKidney_e15.5_Peripheral blastema_500_k2
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_1000

MB21D2 DTWD2 CDC27 FGD6 HNRNPAB SCN1A SCN2A SCN3A GABRA1

1.68e-05819409gudmap_developingKidney_e15.5_Peripheral blastema_1000
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MAP1B SCN1A SCN2A SCN3A GABRA1

1.17e-06198425c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MAP1B SCN1A SCN2A SCN3A GABRA1

1.17e-061984256d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MAP1B SCN1A SCN2A SCN3A GABRA1

1.17e-061984254ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TACC2 SCN1A SCN2A SCN3A

1.37e-0515542477fdae85d36efb776db977eb424b32487ef222e4
ToppCellAdult-Mesenchymal-chondrocyte-D175|Adult / Lineage, Cell type, age group and donor

IGFN1 MAP1B PDGFRL POLR3G

1.88e-0516842414071b961c9bdb54a8259b12a88237b802cbde36
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TACC2 COBLL1 SCN2A SCN3A

2.92e-05188424eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TACC2 COBLL1 SCN2A SCN3A

2.92e-05188424bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B SCN1A SCN2A GABRA1

2.98e-05189424f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

MAP1B ARHGEF7 COBLL1 SCN3A

3.04e-05190424a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B SCN1A SCN2A GABRA1

3.23e-051934245fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SCN1A COBLL1 SCN2A GABRA1

3.37e-05195424787e95fb59c40bba784544b662fac37606ae1427
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MAP1B SCN2A SCN3A GABRA1

3.43e-05196424676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TACC2 COBLL1 SCN2A SCN3A

3.43e-05196424c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MAP1B SCN1A SCN2A GABRA1

3.57e-051984248ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MAP1B SCN2A SCN3A GABRA1

3.57e-051984240ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellStriatum-Neuronal|Striatum / BrainAtlas - Mouse McCarroll V32

MAP1B SCN1A SCN2A GABRA1

3.72e-05200424c888fd487990cad482a4ca47601cdebc0ca3f3ce
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

MAP1B SCN2A SCN3A GABRA1

3.72e-0520042448d801219bc771d6c7e151dc88ca4c179988de85
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Intermediate|GW19 / Sample Type, Dataset, Time_group, and Cell type.

DTWD2 MAP4K1 WDR46

1.97e-04120423eb5b88c47dd4a6f9b55ace24f19d4e81d4ed31e1
ToppCellremission-unassigned|remission / disease stage, cell group and cell class

NUCKS1 IGSF22 TACC2

4.09e-041544234130769829b838cc8a075c87ff6c187f0f507f8b
ToppCellremission-unassigned|World / disease stage, cell group and cell class

NUCKS1 IGSF22 TACC2

4.17e-04155423d81bec894381e3e2d6249a567e8108b8423e5c54
ToppCellRV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

ARHGEF7 COBLL1 SCN3A

4.58e-0416042329c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

NUCKS1 CDCA5 MAP4K1

4.66e-041614230dd1401b4c990d49fccb702a9f9867590a58e203
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

NUCKS1 CDCA5 MAP4K1

4.66e-04161423b6a31c033edc74f23a20aab1f18e80cc83ffee4c
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

MAP1B ARHGEF7 SCN3A

4.66e-0416142347b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCellBac-SEP-Lymphocyte-B-B_intermediate|Bac-SEP / Disease, Lineage and Cell Type

MYL4 COBLL1 SCN2A

4.66e-04161423bcd122af09cbb99d1816200d9c367af8b7f36873
ToppCellPND07-Endothelial-Endothelial_lymphatic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN11A SCN1A SCN3A

4.66e-04161423133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN11A SCN1A SCN3A

4.66e-04161423cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

NUCKS1 CDCA5 MAP4K1

4.66e-04161423efb811dda4d73107983a5f68302bdcf4f408d5b4
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN11A SCN1A SCN3A

4.66e-041614239466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

NUCKS1 CDCA5 MAP4K1

4.66e-0416142328d5dbd20c9f8e0069f172d552997a044790e1a7
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-Plasma_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MB21D2 MYL4 COBLL1

4.75e-041624238278dccdb139396ede34b83b02ebce837f2489d6
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN11A SCN1A SCN3A

4.75e-0416242396c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCelldroplet-Lung-nan-18m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL4 SRBD1 COBLL1

4.83e-041634235efecdd8a069a822bc9d35b407092925a865e629
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYL4 SRBD1 COBLL1

4.83e-041634230d94a427f86e62aba12c397c6d7b8cd297f3a0e5
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TACC2 SCN1A COBLL1

4.92e-04164423b0ed8cb6000ce8bf94444307e4b7b3574fa3fab2
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NUCKS1 CDCA5 MAP4K1

4.92e-04164423249d8f75a64bce7db52ce0c563f496b9edf602a6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 SCN2A SCN3A

4.92e-041644236fb2136168f430babfeb81ca7e151ca7a8092ec4
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TACC2 SCN1A COBLL1

4.92e-041644233aea6207a011ad55a1aeb2ed9fb54d31b23694b5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 SCN2A SCN3A

5.01e-041654239bd332e5ede759a00a47728ea5558c215efdd77a
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

MAP4K1 SCN2A GABRA1

5.01e-041654239795ce31689bc63f5a2d68725ef00b23a90c3846
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

TACC2 SCN1A COBLL1

5.27e-04168423e20e1936573fdde78426d7a4eb45c458d5c4dbb4
ToppCellControl|World / group, cell type (main and fine annotations)

TACC2 SCN1A COBLL1

5.27e-04168423a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

TACC2 SCN1A COBLL1

5.27e-0416842316b517e3159ad6e6d25fd48f7d5f46e77b2b318d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 SCN2A SCN3A

5.37e-041694230332f539a2f7d6dcd081a5d2f567290721f5a329
ToppCell5'-Adult-SmallIntestine-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FGD6 CDCA5 MAP4K1

5.37e-04169423a34aff9257ae9746226ee7af595c4678a4b0c896
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDCA5 MAP4K1 POLR3G

5.65e-04172423ca0cc0e92b6cdce5016f18fcb2ec1508cb222502
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYL4 CDCA5 MAP4K1

5.65e-0417242376c06a968d3333441eed103abef1e636a1c3e7a1
ToppCell3'_v3-blood-Lymphocytic_B-Naive_B_cells|blood / Manually curated celltypes from each tissue

ARMC3 COBLL1 SCN3A

5.65e-04172423f16f90d17feac1ee52fd513907b28456865fd31d
ToppCellEndothelial-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

SCN11A MAP1B SCN3A

5.65e-04172423d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-regulatory_T_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDCA5 MAP4K1 POLR3G

5.65e-04172423425970e9ce8943f7e2ba6ca958e7a3a29baa798c
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MAP1B SCN1A GABRA1

5.74e-041734237e3897868dd3f6e4974f593c60649a543ffc8693
ToppCellBL-critical-LOC-Lymphoid-PC|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

COBLL1 SCN3A POLR3G

5.74e-0417342390700a876d997f7c0f7b3899dffcda7fdafee547
ToppCell3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDGFRL SCN2A SCN3A

5.84e-04174423a62531ebf16b32b249168dca11b870f63a8aa81c
ToppCellCOVID-19-Heart-VSMC|COVID-19 / Disease (COVID-19 only), tissue and cell type

MAP1B ARHGEF7 SCN3A

5.94e-041754231125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 SCN2A SCN3A

5.94e-04175423787ac1a12cda10af5c8830471702a4cbaf43e79e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 SCN2A SCN3A

6.04e-04176423b942227abf9902ba13fac6c3e9efb0cacc82af94
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B SCN1A SCN3A

6.14e-041774231dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 SCN2A SCN3A

6.14e-04177423dc846d0feb94d4c289553cc3ac9dac81d10409cb
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B SCN1A SCN3A

6.14e-04177423426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCelldroplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B COBLL1 SCN3A

6.14e-04177423dbdbdc8ed9ef0b529694242ef9f9f07a42e16005
ToppCellfacs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B COBLL1 SCN3A

6.34e-041794238da6863edc756540bb097cc7221c1408640d9bb4
ToppCell3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCN11A MAP1B SCN3A

6.34e-041794238ce5000088b727783a0619baa16a2cd036d21f54
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 SCN2A SCN3A

6.34e-04179423666072c0e8448dbaec1683d18368ec2502453f90
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SCN1A SCN2A SCN3A

6.34e-04179423af0b54c9ea0b6e4210f22dbb6e88ecd3276a5f86
ToppCellfacs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B COBLL1 SCN3A

6.34e-04179423f39c13c99a07d009cc677e363ffe089089c64916
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDCA5 SCN2A SCN3A

6.45e-04180423401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 SCN2A SCN3A

6.45e-04180423788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN1A SCN2A GABRA1

6.45e-04180423f6a2208960d0df1500c974cc44c3c054cd7475a9
ToppCellfacs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B COBLL1 SCN3A

6.55e-04181423429df38438d5a7ff490c9ede34b69e2970c7ded2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ARMC3 CDCA5 CTR9

6.55e-041814236873c1138b28c130637d06b64981ad11c262e85f
ToppCellRA-07._Pericyte|RA / Chamber and Cluster_Paper

MAP1B ARHGEF7 SCN3A

6.55e-041814238dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCellfacs-Heart-RA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B COBLL1 SCN3A

6.55e-04181423395cf5aa2d89b05328ab516b8c89401020b6d830
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast|PND01-03-samps / Age Group, Lineage, Cell class and subclass

MAP1B PDGFRL SCN2A

6.66e-04182423812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 SCN2A SCN3A

6.66e-041824235f513bbb7125956eb528e3120de3fd776770a7c3
ToppCellGlobus_pallidus-Neuronal-Inhibitory|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MAP1B SCN1A GABRA1

6.66e-0418242304ccfa951eaa31fed6d140edb6c702d49363c5fa
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN11A MAP1B SCN3A

6.66e-04182423398ce074a04f6482470b488f1affae4af7d2ec58
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 SCN2A SCN3A

6.76e-04183423b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 SCN2A SCN3A

6.76e-04183423d340ab5a77e8d819a1dfb4ca3e9a4b9bc988923c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CHD6 CDCA5 POLR3G

6.76e-04183423ba7753e9fe2a6a87c5264f299ac97da2ddbda178
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

ARHGEF7 COBLL1 SCN3A

6.76e-04183423818fd886e0188091310825f9145fa53328f2c979
ToppCellLV-07._Pericyte|World / Chamber and Cluster_Paper

MAP1B ARHGEF7 SCN3A

6.76e-04183423273db6a3b00a93ca852498471187b642b5368185
ToppCellLA-07._Pericyte|World / Chamber and Cluster_Paper

MAP1B ARHGEF7 SCN3A

6.76e-04183423e3835db4795362b0442d5893baf2a78efcc20428
ToppCellfacs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B COBLL1 SCN3A

6.76e-041834238d45dff06a199b1369576657f7f9dc0249c5f841
ToppCellfacs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B COBLL1 SCN3A

6.76e-04183423421265fa15d5a028cb567bb0904e670473ef102b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 SCN2A SCN3A

6.76e-041834232e831a4d99c6f983793df71c0994124c943c6da9
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

ARHGEF7 COBLL1 SCN3A

6.76e-04183423cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

TACC2 SCN1A COBLL1

6.87e-041844230ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN11A MAP1B SCN3A

6.87e-041844233da93e7d8b62463e307cc0425c47dbd3bef66799
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 SCN2A SCN3A

6.87e-041844239690d4290e70f9bda889754ffb30b0af1f7cb94b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN1A SCN2A GABRA1

6.87e-041844237d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

TACC2 SCN1A COBLL1

6.87e-041844232a8338e94937686a148b5433515700ca0f674058
ToppCellLA-07._Pericyte|LA / Chamber and Cluster_Paper

MAP1B ARHGEF7 SCN3A

6.98e-04185423ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 SCN2A SCN3A

6.98e-041854233d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCell18-Distal-Epithelial-Neuroendocrine|Distal / Age, Tissue, Lineage and Cell class

SCN2A SCN3A GABRA1

6.98e-04185423f8fc7b12b4e18d23d84e95488be93c4352d325f3
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN1A SCN2A GABRA1

6.98e-0418542370de48988c1f8e0809afc8092b663aa439d8e528
ToppCellLV-07._Pericyte|LV / Chamber and Cluster_Paper

MAP1B ARHGEF7 SCN3A

6.98e-04185423acb38eba871ec72f2a8136a33b87d33b8c85465d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 SCN2A SCN3A

7.09e-04186423d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1B SCN2A GABRA1

7.09e-04186423d1d01ce46e62944aa9864eda47e8401b5f0d2bdc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 SCN2A SCN3A

7.09e-0418642308632045d499e61dd96ff29a5a9a208afe58dc58
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 SCN2A SCN3A

7.09e-04186423b3358e0fa6d845c81e94d56c8575f016621d28ff
DrugZonisamide

SCN11A SCN1A SCN2A SCN3A

2.12e-0817414DB00909
DrugAPETx1, Anthopleura elegantissima

SCN10A SCN2A SCN3A

1.08e-076413ctd:C475726
Drugfenpropathrin

SCN10A SCN2A SCN3A

1.08e-076413ctd:C044267
Drug2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate

SCN10A SCN2A SCN3A

3.02e-078413ctd:C489827
DrugMfpa

TAF1 TAF1L

9.48e-063412CID003035615
DrugSodium

SCN10A SCN11A SCN2A SCN3A

1.57e-0584414ctd:D012964
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

PHF2 DIDO1 TACC2 CTCF COBLL1

1.60e-051774153227_DN
Drugtrichostatin A; Down 200; 0.1uM; MCF7; HG-U133A

PHF2 TACC2 CDC27 CTCF COBLL1

1.69e-05179415331_DN
DrugAPETx2 protein, Anthopleura elegantissima

SCN10A SCN2A

1.89e-054412ctd:C501880
Drugcyfluthrin

SCN10A SCN2A SCN3A

1.92e-0529413ctd:C052570
DrugDinoprost trometamol [38362-01-5]; Down 200; 8.4uM; HL60; HT_HG-U133A

PDGFRL MAP4K1 COBLL1 KNOP1 POLR3G

2.55e-051954152446_DN
DrugMelatonin [73-31-4]; Down 200; 17.2uM; HL60; HT_HG-U133A

QSER1 MYL4 PDGFRL COBLL1 POLR3G

2.62e-051964152431_DN
DrugTopiramate

SCN1A GABRA1

3.15e-055412DB00273
Drugbenzocaine

SCN10A SCN2A SCN3A

4.04e-0537413CID000002337
Druglamotrigine

SCN10A SCN2A SCN3A GABRA1

5.60e-05116414CID000003878
DrugCocaine

SCN10A SCN11A

8.80e-058412DB00907
Drugdecamethrin

SCN10A SCN1A SCN2A SCN3A

1.37e-04146414ctd:C017180
DrugNitrazepam

SCN1A GABRA1

1.72e-0411412DB01595
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

PHF2 DIDO1 CTCF COBLL1

2.09e-041634147453_DN
Drugsaxitoxin

SCN10A SCN2A SCN3A

2.19e-0465413CID000037165
Drug2-phenylindole

TAF1 TAF1L

2.44e-0413412CID000013698
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

PHF2 DIDO1 TACC2 CTCF

2.45e-041704141050_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

PHF2 TAF1 CTCF COBLL1

2.50e-041714145441_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA

PHF2 DIDO1 TACC2 CTCF

2.56e-041724141072_DN
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

PHF2 DIDO1 TAF1 CTCF

2.56e-041724145903_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

USP36 PHF2 QSER1 CTCF

2.62e-041734142881_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

PHF2 DIDO1 MYL4 CTCF

2.68e-041744143993_DN
Drug1,2-Dsmgg

SCN10A SCN11A

2.84e-0414412CID000193820
DrugT2755

SCN10A SCN3A GABRA1

2.85e-0471413CID000005514
Drugflecainide

SCN10A SCN11A SCN3A

2.85e-0471413CID000003355
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

PHF2 DIDO1 TACC2 CTCF

2.92e-04178414992_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

PHF2 DIDO1 CTCF COBLL1

2.92e-041784141112_DN
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; PC3; HT_HG-U133A

DIDO1 TACC2 CTCF ARHGEF7

3.04e-041804144541_DN
Druggeldanamycin; Up 200; 1uM; MCF7; HT_HG-U133A_EA

DIDO1 MYL4 MAP1B PDGFRL

3.18e-041824141008_UP
Drugapholate

SCN10A SCN11A

3.27e-0415412CID000005845
DrugAmpyrone [83-07-8]; Down 200; 19.6uM; PC3; HT_HG-U133A

USP36 KMT2A TAF1 MAP1B

3.74e-041904144507_DN
DrugChloroquine diphosphate [50-63-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A

USP36 KMT2A MYL4 POLR3G

3.74e-041904142869_DN
Drug2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A_EA

KMT2A QSER1 PDGFRL POLR3G

3.81e-04191414994_UP
DrugPronethalol hydrochloride [51-02-5]; Down 200; 15uM; MCF7; HT_HG-U133A

USP36 KMT2A TAF1 CDC27

3.89e-041924144104_DN
DrugForskolin, from Coleus forskohlii; Down 200; 0.5uM; PC3; HT_HG-U133A

USP36 QSER1 MYL4 MAP1B

3.97e-041934147059_DN
Drug5211181; Up 200; 12uM; MCF7; HT_HG-U133A_EA

QSER1 MAP1B PDGFRL POLR3G

3.97e-04193414950_UP
Drug2-propylpentanoic acid; Up 200; 200uM; HL60; HT_HG-U133A

SCN10A PDGFRL MAP4K1 COBLL1

4.04e-041944146173_UP
DrugStachydrine hydrochloride; Down 200; 22.2uM; MCF7; HT_HG-U133A

KMT2A TAF1 ARHGEF7 COBLL1

4.04e-041944142743_DN
Drug(-)-Quinpirole hydrochloride [85760-74-3]; Down 200; 15.6uM; MCF7; HT_HG-U133A

USP36 QSER1 MYL4 COBLL1

4.04e-041944143539_DN
DrugRolipram [61413-54-5]; Up 200; 14.6uM; MCF7; HT_HG-U133A

CTNNA1 TAF1 MYL4 MAP1B

4.12e-041954145330_UP
DrugOxymetazoline hydrochloride [2315-02-8]; Down 200; 13.4uM; MCF7; HT_HG-U133A

USP36 TAF1 ARHGEF7 COBLL1

4.12e-041954142278_DN
DrugBiperiden hydrochloride [1235-82-1]; Down 200; 11.4uM; HL60; HT_HG-U133A

MYL4 MAP1B MAP4K1 COBLL1

4.12e-041954142460_DN
DrugProcarbazine hydrochloride [366-70-1]; Down 200; 15.6uM; HL60; HT_HG-U133A

KMT2A QSER1 MYL4 KNOP1

4.12e-041954142971_DN
DrugPhenethicillin potassium salt [132-93-4]; Down 200; 10uM; PC3; HT_HG-U133A

SCN10A SCN11A TAF1 MYL4

4.12e-041954145763_DN
DrugTolazoline hydrochloride [59-97-2]; Down 200; 20.4uM; MCF7; HT_HG-U133A

USP36 KMT2A PPP2R5D CDC27

4.20e-041964144844_DN
DrugMesoridazine besylate [32672-69-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A

USP36 PPP2R5D ARHGEF7 POLR3G

4.20e-041964147017_DN
DrugRapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A

QSER1 PDGFRL COBLL1 GABRA1

4.20e-041964142681_UP
DrugPD 150606

SCN2A SCN3A

4.23e-0417412ctd:C100442
Drugclf2

MYL4 CDC27

4.23e-0417412CID000141144
DrugVigabatrin [60643-86-9]; Down 200; 31uM; HL60; HT_HG-U133A

QSER1 MYL4 MAP1B MAP4K1

4.29e-041974142452_DN
DrugHexetidine [141-94-6]; Down 200; 11.8uM; HL60; HT_HG-U133A

QSER1 MYL4 MAP4K1 COBLL1

4.29e-041974142457_DN
DrugVancomycin hydrochloride [1404-93-9]; Up 200; 2.6uM; MCF7; HT_HG-U133A

SCN10A USP36 KMT2A TAF1

4.29e-041974142858_UP
DrugRetrorsine [480-54-6]; Up 200; 11.4uM; HL60; HT_HG-U133A

KMT2A MYL4 MAP4K1 POLR3G

4.29e-041974142129_UP
DrugHexylcaine hydrochloride [532-76-3]; Up 200; 13.4uM; MCF7; HT_HG-U133A

SCN10A USP36 DIDO1 MYL4

4.29e-041974143447_UP
DrugClofazimine [2030-63-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A

MYL4 MAP1B PDGFRL POLR3G

4.29e-041974143239_DN
DrugParomomycin sulfate [1263-89-4]; Up 200; 5.6uM; HL60; HT_HG-U133A

CTNNA1 MAP4K1 RAI1 GABRA1

4.37e-041984143017_UP
Drugnocodazole; Down 200; 1uM; MCF7; HG-U133A

KMT2A DIDO1 TACC2 SRBD1

4.37e-04198414621_DN
Drug9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A

PHF2 DIDO1 TAF1 PDGFRL

4.37e-041984147557_DN
DrugEthoxyquin [91-53-2]; Up 200; 18.4uM; HL60; HT_HG-U133A

SCN11A CTNNA1 MYL4 MAP1B

4.37e-041984142559_UP
DrugGlimepiride [93479-97-1]; Up 200; 8.2uM; HL60; HT_HG-U133A

SCN10A MYL4 MAP4K1 COBLL1

4.37e-041984142154_UP
DrugMyricetin [529-44-2]; Down 200; 12.6uM; PC3; HT_HG-U133A

DIDO1 TACC2 QSER1 MAP1B

4.37e-041984144090_DN
DrugCeforanide [60925-61-3]; Down 200; 7.6uM; HL60; HT_HG-U133A

QSER1 MYL4 COBLL1 POLR3G

4.37e-041984142447_DN
Drugchlorpromazine hydrochloride; Down 200; 1uM; MCF7; HG-U133A

KMT2A TAF1 ARHGEF7 COBLL1

4.37e-04198414426_DN
DrugMevalonic-D, L acid lactone [674-26-0]; Down 200; 30.8uM; PC3; HT_HG-U133A

SCN10A SCN11A MYL4 MAP1B

4.37e-041984145738_DN
DrugTrimethoprim [738-70-5]; Up 200; 13.8uM; MCF7; HT_HG-U133A

TAF1 QSER1 MAP4K1 COBLL1

4.37e-041984144701_UP
DrugOxybenzone [131-57-7]; Down 200; 17.6uM; HL60; HT_HG-U133A

SCN10A KMT2A QSER1 MYL4

4.37e-041984143092_DN
Drug(-)-MK 801 hydrogen maleate [77086-19-2]; Up 200; 11.8uM; PC3; HT_HG-U133A

SCN11A CTNNA1 COBLL1 SCN2A

4.37e-041984146657_UP
DrugHydroxyzine dihydrochloride [2192-20-3]; Down 200; 9uM; HL60; HG-U133A

KMT2A DIDO1 CDC27 ARHGEF7

4.45e-041994142024_DN
DrugPropylthiouracil [51-52-5]; Up 200; 23.4uM; HL60; HT_HG-U133A

SCN10A SCN11A CTNNA1 COBLL1

4.45e-041994142476_UP
DrugScorpion Venoms

SCN2A SCN3A

4.75e-0418412ctd:D012604
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN10A SCN11A SCN1A SCN2A SCN3A

1.14e-1210425DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN10A SCN11A SCN1A SCN2A SCN3A

1.14e-1210425DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN10A SCN11A SCN1A SCN2A SCN3A

3.59e-1212425DOID:0060170 (implicated_via_orthology)
DiseaseNeurodevelopmental Disorders

PHF2 KMT2A PPP2R5D SCN1A SCN2A

2.16e-0793425C1535926
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A SCN2A GABRA1

7.59e-0713423C0751122
DiseaseIntellectual Disability

TAF1 PPP2R5D MAP1B CTCF SCN1A RAI1 SCN3A

2.98e-06447427C3714756
Diseaseepilepsy (implicated_via_orthology)

SCN10A SCN11A SCN1A SCN2A SCN3A

3.49e-06163425DOID:1826 (implicated_via_orthology)
Diseaseanxiety disorder (implicated_via_orthology)

SCN1A SCN2A SCN3A

4.05e-0622423DOID:2030 (implicated_via_orthology)
DiseasePAROXYSMAL EXTREME PAIN DISORDER

SCN10A SCN11A

5.93e-063422C1833661
DiseasePrimary Erythermalgia

SCN10A SCN11A

5.93e-063422C0014805
DiseaseHereditary Sensory Autonomic Neuropathy, Type 5

SCN10A SCN11A

4.13e-057422C0020075
DiseaseSeizure, Febrile, Simple

SCN1A SCN2A

4.13e-057422C0149886
DiseaseSeizure, Febrile, Complex

SCN1A SCN2A

4.13e-057422C0751057
DiseaseCongenital Pain Insensitivity

SCN10A SCN11A

4.13e-057422C0002768
DiseaseFebrile Convulsions

SCN1A SCN2A

7.08e-059422C0009952
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN2A

7.08e-059422C3502809
Diseasesleep time

MB21D2 ARMC3

8.84e-0510422EFO_0005274
Diseasetransient cerebral ischemia (implicated_via_orthology)

KMT2A HNRNPAB MAP4K1

1.05e-0464423DOID:224 (implicated_via_orthology)
Diseasecongenital heart disease (implicated_via_orthology)

USP36 KMT2A CHD6

1.32e-0469423DOID:1682 (implicated_via_orthology)
Diseaseinterleukin 18 measurement

SCN10A SCN11A MAP1B

1.75e-0476423EFO_0004581
DiseaseMMR-related febrile seizures

SCN1A SCN2A

2.05e-0415422EFO_0006519
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

SCN1A SCN2A

2.34e-0416422C0393706
Diseaseuridine diphosphate galactose measurement, uridine diphosphate glucose measurement

IGFN1 SRBD1

2.65e-0417422EFO_0010543, EFO_0010544
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

SCN1A SCN2A

2.98e-0418422HP_0002373
Diseasesocial communication impairment

SCN10A SCN11A

9.55e-0432422EFO_0005427
Diseaseautism spectrum disorder (implicated_via_orthology)

CHD6 SCN1A SCN2A

1.33e-03152423DOID:0060041 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
PPEKQKRKKKKMPEI

CDCA5

211

Q96FF9
VGNMKPPKPTKIKKK

CTCF

246

P49711
MPYKLKKEKEPPKVA

PPP2R5D

1

Q14738
SPKTMKKLLPKRKPE

ARHGEF7

676

Q14155
MGKKIKKEVEPPPKD

ARMC3

1

Q5W041
PKPMPKNKRKLRKME

DTWD2

276

Q8NBA8
VILKPKMLDKKKPTP

COBLL1

126

Q53SF7
KMLDKKKPTPIIPEK

COBLL1

131

Q53SF7
CLPKKKPKLKEKVRP

RAI1

1711

Q7Z5J4
KVKQPKVKAEPPPKK

QSER1

1486

Q2KHR3
MVKKSKPERKEKKMP

NUCKS1

156

Q9H1E3
KPERKEKKMPKPRLK

NUCKS1

161

Q9H1E3
KLVPKHKKKIQPRKM

H1-8

126

Q8IZA3
KPPKVESKEKVMVKK

MAP1B

576

P46821
KKPQRGMPKVEKVEK

MB21D2

201

Q8IYB1
GQAPEMPLVKKKKKK

KNOP1

56

Q1ED39
PEKPKKVKDPLIKKN

GABRA1

351

P14867
MAPKKPEPKKEAAKP

MYL4

1

P12829
FKKMLKKRAPPAPKK

IGSF22

166

Q8N9C0
MKAPEKKPLVKREKQ

CTNNA1

861

P35221
EPKEPRKAKEPKKAK

CHD6

126

Q8TD26
KKKAPKPERLPPSMK

CTR9

991

Q6PD62
EKMKMKPEKPSLPKC

DIDO1

441

Q9BTC0
KQKPKEKEKPPPVNK

KMT2A

1356

Q03164
KKRAPPAPKKKMDLE

IGFN1

151

Q86VF2
LKMKFPPKIPNRKTK

CDC27

396

P30260
LDKPPLLPPKKEKMK

MAP4K1

466

Q92918
PKKAMAMKKDPVKKI

HNRNPAB

141

Q99729
KKTPKTVKMPKPSKI

PHF2

491

O75151
PEKKPKKMKERPDLK

TAF1L

1266

Q8IZX4
PPEKKPKKMKERPDL

TAF1

1246

P21675
KKRPPPVEKKKILGM

CCT8L1P

541

A6NM43
MKKLGSKKPQKPIPR

SCN3A

1496

Q9NY46
TNKKVKPKIPKMKDR

PDGFRL

41

Q15198
PKESKPKRMPRVKKN

SRBD1

56

Q8N5C6
MKKLGSKKPQKPIPR

SCN1A

1511

P35498
MKKLGSKKPQKPIPR

SCN10A

1446

Q9Y5Y9
KKMKPAIAPKPKVLK

FGD6

46

Q6ZV73
MKKLGSKKPQKPIPR

SCN2A

1501

Q99250
MPRNKCKKAGPKPKK

POLR3G

111

O15318
KKPVAKMPLRRPKMK

TACC2

2291

O95359
KMPLRRPKMKKTPEK

TACC2

2296

O95359
VPPKKDKLQTKRKKP

WDR46

11

O15213
MKKLGSKKPQKPIPR

SCN11A

1336

Q9UI33
PEAMEESPRKKKKKK

USP36

946

Q9P275