Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionreelin receptor activity

VLDLR LRP8

7.12e-0521692GO:0038025
GeneOntologyMolecularFunctionubiquitin protein ligase activity

VPS18 TRIM73 TRIM35 RNF181 RNF175 ZNRF2 RNF43 TRIM23 ZNRF1 TRIM50 TRIM74 RNF111

8.09e-0537216912GO:0061630
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

VPS18 TRIM73 TRIM35 RNF181 RNF175 ZNRF2 RNF43 TRIM23 ZNRF1 TRIM50 TRIM74 RNF111

1.52e-0439816912GO:0061659
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

VPS18 TRIM73 TRIM35 RNF181 RNF175 ZNRF2 RNF43 TRIM23 ZNRF1 TNFAIP1 TRIM50 TRIM74 RNF111

2.02e-0447316913GO:0004842
GeneOntologyMolecularFunctionmRNA regulatory element binding translation repressor activity

CPEB2 CPEB3 CPEB4

3.71e-04171693GO:0000900
GeneOntologyMolecularFunctionvery-low-density lipoprotein particle receptor activity

VLDLR LRP8

4.23e-0441692GO:0030229
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

VPS18 TRIM73 TRIM35 RNF181 RNF175 ZNRF2 RNF43 TRIM23 ZNRF1 TNFAIP1 TRIM50 TRIM74 RNF111

4.31e-0451216913GO:0019787
GeneOntologyMolecularFunctionaminoacyltransferase activity

VPS18 TRIM73 TRIM35 RNF181 RNF175 ZNRF2 RNF43 TRIM23 ZNRF1 TNFAIP1 TRIM50 TRIM74 RNF111

6.16e-0453216913GO:0016755
GeneOntologyMolecularFunctiontranslation factor activity, RNA binding

CPEB2 CPEB3 CPEB4 GCN1 EIF3M

7.78e-04851695GO:0008135
GeneOntologyBiologicalProcessprotein ubiquitination

VPS18 KLHL10 LZTR1 TRIM73 TRIM35 RNF181 ZNRF2 RNF43 TRIM23 USP44 DCAF10 USP7 ZNRF1 GAN TNFAIP1 TRIM50 TRIM74 RNF111 WDTC1

3.56e-0581116819GO:0016567
GeneOntologyBiologicalProcessprotein modification by small protein conjugation

VPS18 KLHL10 LZTR1 TRIM73 TRIM35 RNF181 RELA ZNRF2 RNF43 TRIM23 USP44 DCAF10 USP7 ZNRF1 GAN TNFAIP1 TRIM50 TRIM74 RNF111 WDTC1

4.12e-0589316820GO:0032446
GeneOntologyBiologicalProcessnegative regulation of cytoplasmic translation

CPEB2 CPEB3 CPEB4

6.11e-05101683GO:2000766
GeneOntologyBiologicalProcesspost-translational protein modification

VPS18 KLHL10 LZTR1 TRIM73 TRIM35 RNF181 RELA ZNRF2 RNF43 TRIM23 USP44 JAK2 DCAF10 USP7 ZNRF1 GAN TNFAIP1 TRIM50 USP3 TRIM74 RNF111 WDTC1

6.31e-05107416822GO:0043687
GeneOntologyBiologicalProcessnegative regulation of cytoplasmic translational elongation

CPEB2 CPEB3

6.60e-0521682GO:1900248
GeneOntologyBiologicalProcessprotein modification by small protein conjugation or removal

VPS18 KLHL10 LZTR1 TRIM73 TRIM35 RNF181 RELA ZNRF2 RNF43 TRIM23 USP44 DCAF10 USP7 ZNRF1 GAN TNFAIP1 TRIM50 USP3 TRIM74 RNF111 WDTC1

7.50e-05100916821GO:0070647
GeneOntologyCellularComponentAP-3 adaptor complex

VPS18 AP3S1 VPS41 AP3S2

2.66e-06131674GO:0030123
Domain-

TRIM73 TRIM35 RNF181 RNF175 KDM5D FBXL19 SP110 ZNRF2 RNF43 TRIM23 USP44 VPS41 ZNRF1 TRIM50 USP3 TRIM74 RNF111

5.51e-07449166173.30.40.10
DomainZnf_RING/FYVE/PHD

TRIM73 TRIM35 RNF181 RNF175 KDM5D FBXL19 SP110 ZNRF2 RNF43 TRIM23 USP44 VPS41 ZNRF1 TRIM50 USP3 TRIM74 RNF111

7.47e-0745916617IPR013083
DomainZF_RING_1

VPS18 TRIM73 TRIM35 RNF181 RNF175 ZNRF2 RNF43 TRIM23 VPS41 ZNRF1 TRIM50 TRIM74 RNF111

2.10e-0629116613PS00518
DomainZF_RING_2

VPS18 TRIM73 TRIM35 RNF181 RNF175 ZNRF2 RNF43 TRIM23 VPS41 ZNRF1 TRIM50 TRIM74 RNF111

2.73e-0629816613PS50089
DomainCEBP_ZZ

CPEB2 CPEB3 CPEB4

2.74e-0641663PF16366
DomainRRM_7

CPEB2 CPEB3 CPEB4

2.74e-0641663PF16367
DomainCEBP_ZZ

CPEB2 CPEB3 CPEB4

2.74e-0641663IPR032296
Domainzf-C3HC4

TRIM73 TRIM35 RNF181 RNF175 ZNRF2 RNF43 TRIM23 ZNRF1 TRIM50 TRIM74 RNF111

5.12e-0622316611PF00097
DomainZnf_RING

VPS18 TRIM73 TRIM35 RNF181 RNF175 ZNRF2 RNF43 TRIM23 VPS41 ZNRF1 TRIM50 TRIM74 RNF111

7.24e-0632616613IPR001841
DomainRING

TRIM73 TRIM35 RNF181 RNF175 ZNRF2 RNF43 TRIM23 VPS41 ZNRF1 TRIM50 TRIM74 RNF111

1.88e-0530516612SM00184
DomainZnf_C3HC4_RING-type

TRIM73 TRIM35 RNF181 ZNRF2 RNF43 ZNRF1 TRIM50 TRIM74 RNF111

2.37e-051721669IPR018957
DomainBBOX

TRIM73 TRIM35 TRIM23 TRIM16 TRIM50 TRIM74

3.40e-05691666SM00336
Domainzf-B_box

TRIM73 TRIM35 TRIM23 TRIM16 TRIM50 TRIM74

4.33e-05721666PF00643
Domain-

VLDLR TMPRSS13 LRP8 TMPRSS3 TMPRSS7

5.33e-054616654.10.400.10
DomainLDLRA_1

VLDLR TMPRSS13 LRP8 TMPRSS3 TMPRSS7

6.56e-05481665PS01209
DomainLDrepeatLR_classA_rpt

VLDLR TMPRSS13 LRP8 TMPRSS3 TMPRSS7

7.26e-05491665IPR002172
DomainLDLa

VLDLR TMPRSS13 LRP8 TMPRSS3 TMPRSS7

7.26e-05491665SM00192
DomainLDLRA_2

VLDLR TMPRSS13 LRP8 TMPRSS3 TMPRSS7

7.26e-05491665PS50068
DomainZF_BBOX

TRIM73 TRIM35 TRIM23 TRIM16 TRIM50 TRIM74

7.86e-05801666PS50119
DomainZnf_B-box

TRIM73 TRIM35 TRIM23 TRIM16 TRIM50 TRIM74

8.43e-05811666IPR000315
Domainzf-RING_2

RNF181 ZNRF2 RNF43 ZNRF1 RNF111

9.68e-05521665PF13639
DomainARM-type_fold

DOCK11 RTTN HEATR1 LYST NCAPG2 ARID2 GCN1 UNC79 EIF3M GPRASP2 IPO11

2.32e-0433916611IPR016024
Domain-

TRIM73 TRIM35 TRIM16 TRIM50 TRIM74

4.24e-047116654.10.45.10
DomainLDLR_class-A_CS

VLDLR LRP8 TMPRSS3 TMPRSS7

4.29e-04401664IPR023415
Domain-

PSMD11 TOMM70 VPS41 GPSM2 STIP1 TTC22 CLUH WDTC1

5.38e-0420716681.25.40.10
DomainBTB

KLHL6 KLHL10 LZTR1 ZBTB8A MYNN GAN TNFAIP1

5.77e-041601667PS50097
DomainLdl_recept_a

VLDLR LRP8 TMPRSS3 TMPRSS7

6.75e-04451664PF00057
Domain-

SEMA3F APAF1 LYST DCAF10 WDR11 WDR20 VPS41 DMWD WDTC1 WDR72

8.11e-04333166102.130.10.10
DomainWD40/YVTN_repeat-like_dom

SEMA3F APAF1 LYST DCAF10 WDR11 WDR20 VPS41 DMWD WDTC1 WDR72

8.49e-0433516610IPR015943
DomainBTB

KLHL6 KLHL10 LZTR1 ZBTB8A MYNN GAN

1.13e-031311666PF00651
DomainBTB

KLHL6 KLHL10 LZTR1 ZBTB8A MYNN GAN TNFAIP1

1.15e-031801667SM00225
DomainTPR-like_helical_dom

PSMD11 TOMM70 VPS41 GPSM2 STIP1 TTC22 CLUH WDTC1

1.16e-032331668IPR011990
DomainTPR_1

TOMM70 GPSM2 STIP1 TTC22 WDTC1

1.25e-03901665IPR001440
DomainTPR_1

TOMM70 GPSM2 STIP1 TTC22 WDTC1

1.25e-03901665PF00515
DomainBTB/POZ_dom

KLHL6 KLHL10 LZTR1 ZBTB8A MYNN GAN TNFAIP1

1.35e-031851667IPR000210
Domain-

TMPRSS13 TMPRSS3 HHIPL1

1.37e-032516633.10.250.10
DomainSR

TMPRSS13 TMPRSS3 HHIPL1

1.37e-03251663SM00202
DomainWD40_repeat_dom

APAF1 LYST DCAF10 WDR11 WDR20 VPS41 DMWD WDTC1 WDR72

1.38e-032971669IPR017986
DomainSKP1/BTB/POZ

KLHL6 KLHL10 LZTR1 ZBTB8A MYNN GAN TNFAIP1

1.53e-031891667IPR011333
DomainSRCR-like_dom

TMPRSS13 TMPRSS3 HHIPL1

1.54e-03261663IPR017448
DomainSRCR_1

TMPRSS13 TMPRSS3 HHIPL1

1.54e-03261663PS00420
DomainSRCR_2

TMPRSS13 TMPRSS3 HHIPL1

1.54e-03261663PS50287
DomainClathrin

VPS18 VPS41

1.60e-0371662PF00637
DomainGS_dom

ACVR1C BMPR1B

1.60e-0371662IPR003605
DomainGS

ACVR1C BMPR1B

1.60e-0371662PS51256
DomainTGF_beta_GS

ACVR1C BMPR1B

1.60e-0371662PF08515
DomainSRCR_2

TMPRSS13 TMPRSS3

1.60e-0371662PF15494
DomainGS

ACVR1C BMPR1B

1.60e-0371662SM00467
DomainCHCR

VPS18 VPS41

1.60e-0371662PS50236
DomainAP_complex_ssu

AP3S1 AP3S2

1.60e-0371662IPR016635
DomainSRCR

TMPRSS13 TMPRSS3 HHIPL1

1.72e-03271663IPR001190
DomainHEAT

HEATR1 NCAPG2 GCN1 IPO11

1.76e-03581664IPR000357
DomainKelch

KLHL6 KLHL10 LZTR1 GAN

1.76e-03581664SM00612
DomainGal_Oxase/kelch_b-propeller

KLHL6 KLHL10 LZTR1 GAN

1.87e-03591664IPR011043
DomainClathrin_H-chain/VPS_repeat

VPS18 VPS41

2.12e-0381662IPR000547
DomainWD40

APAF1 LYST DCAF10 WDR11 WDR20 DMWD WDTC1 WDR72

2.25e-032591668PF00400
DomainCLAT_ADAPTOR_S

AP3S1 AP3S2

2.71e-0391662PS00989
DomainWD40

APAF1 LYST DCAF10 WDR11 WDR20 DMWD WDTC1 WDR72

2.78e-032681668SM00320
DomainARM-like

RTTN HEATR1 NCAPG2 KATNBL1 ARID2 GCN1 GPRASP2 IPO11

2.91e-032701668IPR011989
DomainWD40_repeat

APAF1 LYST DCAF10 WDR11 WDR20 DMWD WDTC1 WDR72

3.05e-032721668IPR001680
Domainzf-RING_UBOX

TRIM73 TRIM50 TRIM74

3.37e-03341663PF13445
DomainZnf-RING_LisH

TRIM73 TRIM50 TRIM74

3.37e-03341663IPR027370
DomainActivin_recp

ACVR1C BMPR1B

3.37e-03101662PF01064
DomainActivin_recp

ACVR1C BMPR1B

3.37e-03101662IPR000472
DomainWD_REPEATS_1

APAF1 LYST DCAF10 WDR11 WDR20 DMWD WDTC1 WDR72

3.48e-032781668PS00678
DomainHEAT_REPEAT

HEATR1 NCAPG2 GCN1 IPO11

3.50e-03701664PS50077
DomainKelch_1

KLHL6 KLHL10 LZTR1 GAN

3.50e-03701664PF01344
DomainKelch_1

KLHL6 KLHL10 LZTR1 GAN

3.50e-03701664IPR006652
DomainWD_REPEATS_2

APAF1 LYST DCAF10 WDR11 WDR20 DMWD WDTC1 WDR72

3.55e-032791668PS50082
DomainWD_REPEATS_REGION

APAF1 LYST DCAF10 WDR11 WDR20 DMWD WDTC1 WDR72

3.55e-032791668PS50294
DomainTPR_REGION

TOMM70 GPSM2 STIP1 TTC22 CLUH WDTC1

3.61e-031651666PS50293
DomainTPR

TOMM70 GPSM2 STIP1 TTC22 CLUH WDTC1

3.61e-031651666PS50005
DomainDEAD/DEAH_box_helicase_dom

DDX47 DDX31 TDRD9 DICER1

4.07e-03731664IPR011545
DomainDEAD

DDX47 DDX31 TDRD9 DICER1

4.07e-03731664PF00270
DomainZnF_UBP

USP44 USP3

4.10e-03111662SM00290
DomainTGFB_receptor

ACVR1C BMPR1B

4.89e-03121662IPR000333
DomainClathrin_sm-chain_CS

AP3S1 AP3S2

4.89e-03121662IPR000804
Domain-

VLDLR LRP8 HHIPL1

4.98e-033916632.120.10.30
DomainKinesin_motor_CS

STARD9 KIF2A KIF13A

5.74e-03411663IPR019821
DomainPkinase_Tyr

ACVR1C BLK JAK2 BMPR1B BMX

5.93e-031291665PF07714
DomainTPR

TOMM70 GPSM2 STIP1 TTC22 WDTC1

5.93e-031291665SM00028
DomainPRY

TRIM35 TRIM16 TRIM50

6.14e-03421663PF13765
DomainBTB-kelch_protein

KLHL6 KLHL10 GAN

6.56e-03431663IPR017096
DomainZnf_UBP

USP44 USP3

6.66e-03141662IPR001607
Domainzf-UBP

USP44 USP3

6.66e-03141662PF02148
DomainTUDOR

TDRD9 SND1

6.66e-03141662PF00567
DomainLdl_recept_b

VLDLR LRP8

6.66e-03141662PF00058
DomainLDLRB

VLDLR LRP8

6.66e-03141662PS51120
DomainZF_UBP

USP44 USP3

6.66e-03141662PS50271
DomainTPR_repeat

TOMM70 GPSM2 STIP1 TTC22 WDTC1

6.74e-031331665IPR019734
Domain-

STARD9 KIF2A KIF13A

6.99e-034416633.40.850.10
DomainKinesin

STARD9 KIF2A KIF13A

6.99e-03441663PF00225
DomainKISc

STARD9 KIF2A KIF13A

6.99e-03441663SM00129
DomainKINESIN_MOTOR_1

STARD9 KIF2A KIF13A

6.99e-03441663PS00411
DomainKinesin_motor_dom

STARD9 KIF2A KIF13A

6.99e-03441663IPR001752
DomainKINESIN_MOTOR_2

STARD9 KIF2A KIF13A

6.99e-03441663PS50067
DomainEGF_CA

VLDLR MATN2 LRP8 THBS4

7.26e-03861664PF07645
Domain-

KDM5D ARID2

7.64e-031516621.10.150.60
DomainBRIGHT

KDM5D ARID2

7.64e-03151662SM00501
DomainARID_dom

KDM5D ARID2

7.64e-03151662IPR001606
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

DDX47 MYH9 THNSL1 POLDIP3 POLR3H PSMD11 SRBD1 DICER1 NUP205 USP44 SND1 SSU72 AFP WDR20 USP7 STIP1 TNFAIP1 DMWD USP3 GCN1 EIF3M GPRASP2 WDTC1

9.00e-1010051702319615732
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

DDX47 EPRS1 MYH9 POLDIP3 OAS3 PSMD11 HEATR1 PPA1 SRBD1 EPB41L3 NCAPG2 ZBED5 NUP205 CDC45 RLF AP3S1 NOP14 SND1 WDR11 USP7 PRMT1 KIF2A USP3 GCN1 EIF3M

1.17e-0813531702529467282
Pubmed

CPEB2, a novel putative translational regulator in mouse haploid germ cells.

CPEB2 CPEB3 CPEB4

1.15e-073170312672660
Pubmed

Gene structure variation in segmental duplication block C of human chromosome 7q 11.23 during primate evolution.

TRIM73 TRIM50 TRIM74

1.15e-073170326196062
Pubmed

TRIM50 protein regulates vesicular trafficking for acid secretion in gastric parietal cells.

TRIM73 TRIM50 TRIM74

1.15e-073170322872646
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

KLHL6 VPS18 MYH9 HEATR1 NCAPG2 DICER1 GPR107 NUP205 CDC45 RLF TRIM16 LIMS1 THRB ARID2 WDR20 VPS41 USP7 PRMT1 STIP1 USP3 GCN1 EIF3M RABIF

1.50e-0713271702332694731
Pubmed

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.

KLHL6 VPS18 KLHL10 TRIM73 DNAAF9 ACVR1C BLK BMX VPS41 GAN TRIM74 RNF111

3.38e-073721701222939624
Pubmed

CPEB2-dependent translation of long 3'-UTR Ucp1 mRNA promotes thermogenesis in brown adipose tissue.

CPEB2 CPEB3 CPEB4

4.57e-074170330177570
Pubmed

Two previously undescribed members of the mouse CPEB family of genes and their inducible expression in the principal cell layers of the hippocampus.

CPEB2 CPEB3 CPEB4

4.57e-074170312871996
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

DDX47 EPRS1 MYH9 HSP90AB4P POLDIP3 PSMD11 HEATR1 PPA1 EPB41L3 DICER1 NUP205 CDC45 TOMM70 SND1 STARD9 USP7 EHMT1 PRMT1 STIP1 KIF2A GCN1 CLUH EIF3M

5.22e-0714251702330948266
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

DDX47 VLDLR ACTR8 SPAM1 LZTR1 AOX1 L1TD1 OAS3 EPB41L3 SP110 DICER1 RNF43 AP3S1 ARID2 WDR20 CPEB4 USP7 EHMT1 WDTC1 WDR72

6.23e-0711161702031753913
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

EPRS1 MYH9 RAPH1 PCDHGB1 PPP1R12B HKDC1 MYNN HEATR1 SRBD1 DCC EPB41L3 LYST NDUFV2 NUP205 TRIM16 BMPR1B NOP14 LATS2 SND1 STARD9 TMPRSS7 DMWD TOP3B

6.40e-0714421702335575683
Pubmed

HAUSP regulates c-MYC expression via de-ubiquitination of TRRAP.

MYH9 MYNN SP110 DICER1 USP7

6.53e-0734170525925205
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

MYH9 RADX PPP1R12B HEATR1 DICER1 TBC1D24 TOMM70 DCAF10 SND1 WDR11 USP7 GCN1 EIF3M GPRASP2 IPO11 WDTC1

1.03e-067541701633060197
Pubmed

Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice.

TRIM73 TRIM50 TRIM74

1.14e-065170320049703
Pubmed

A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons.

CPEB2 CPEB3 CPEB4

1.14e-065170320639532
Pubmed

Williams-Beuren syndrome TRIM50 encodes an E3 ubiquitin ligase.

TRIM73 TRIM50 TRIM74

1.14e-065170318398435
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

VPS18 HSP90AB4P PPP1R12B PSMD11 PPA1 NCAPG2 DICER1 LRP8 NUP205 TRIM16 TBC1D8 JAK2 TOMM70 BMPR1B VPS41 STIP1 IPO11 GNPAT WDR72

1.23e-0610611701933845483
Pubmed

A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system.

TRIM35 RNF181 ZNRF2 RNF43 VPS41 ZNRF1 RNF111

1.97e-06118170719690564
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SEMA3F LZTR1 RTTN FBXL19 LYST RNF43 ADCY7 TBC1D24 JAK2 CCDC88C LATS2 SND1 SSU72 USP7 EHMT1 ZNRF1 DMWD GCN1 TOP3B

2.22e-0611051701935748872
Pubmed

TRIM50 regulates Beclin 1 proautophagic activity.

TRIM73 TRIM50 TRIM74

2.27e-066170329604308
Pubmed

TRIM50 promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization.

TRIM73 TRIM50 TRIM74

2.27e-066170336178239
Pubmed

Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression.

TRIM73 TRIM50 TRIM74

3.96e-067170326025256
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

LZTR1 DDX31 RAPH1 PPP1R12B RELA PSMD11 ARHGAP5 TOMM70 FBXL16 NOP14 WDR11 SSU72 WDR20 USP7 STIP1 DMWD GCN1 TOP3B

4.30e-0610491701827880917
Pubmed

Physiological and pathophysiological characteristics of ataxin-3 isoforms.

EPRS1 MYH9 POLDIP3 RELA PSMD11 USP7 PRMT1 STIP1 GCN1

1.10e-05281170930455355
Pubmed

Insight into bacterial virulence mechanisms against host immune response via the Yersinia pestis-human protein-protein interaction network.

MATN2 RELA PLSCR1

1.34e-0510170321911467
Pubmed

Deficiency of CPEB2-Confined Choline Acetyltransferase Expression in the Dorsal Motor Nucleus of Vagus Causes Hyperactivated Parasympathetic Signaling-Associated Bronchoconstriction.

CPEB2 CPEB3 CPEB4

1.34e-0510170327810937
Pubmed

HIV-1 Vpu inhibits accumulation of the envelope glycoprotein within clathrin-coated, Gag-containing endosomes.

AP3S1 CD63 AP3S2

1.34e-0510170318076669
Pubmed

An investigation into the human serum "interactome".

DCC DICER1 NLRC4 CDC45 RLF CACNA1I GCN1

1.59e-05162170715174051
Pubmed

Screening of 38 genes identifies mutations in 62% of families with nonsyndromic deafness in Turkey.

TMPRSS3 PCDH15

2.38e-052170221117948
Pubmed

The Drosophila ZNRF1/2 homologue, detour, interacts with HOPS complex and regulates autophagy.

ZNRF2 ZNRF1

2.38e-052170238360932
Pubmed

Stress-induced phosphoprotein-1 maintains the stability of JAK2 in cancer cells.

JAK2 STIP1

2.38e-052170227409672
Pubmed

Effect of photoperiodic alterations on depression-like behavior and the brain serotonin system in mice genetically different in tryptophan hydroxylase 2 activity.

HTR2A TPH2

2.38e-052170230685409
Pubmed

USP7 reduces the level of nuclear DICER, impairing DNA damage response and promoting cancer progression.

DICER1 USP7

2.38e-052170237867415
Pubmed

The reelin receptors VLDLR and ApoER2 regulate sensorimotor gating in mice.

VLDLR LRP8

2.38e-052170217261317
Pubmed

Linkage of schizophrenia with TPH2 and 5-HTR2A gene polymorphisms in the Malay population.

HTR2A TPH2

2.38e-052170220623453
Pubmed

Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomes.

CD63 AP3S2

2.38e-052170211907283
Pubmed

ApoER2 and VLDLR in the developing human telencephalon.

VLDLR LRP8

2.38e-052170221601501
Pubmed

Ternary complex of Kif2A-bound tandem tubulin heterodimers represents a kinesin-13-mediated microtubule depolymerization reaction intermediate.

KIF2A KIF13A

2.38e-052170229980677
Pubmed

The RNA binding protein CPEB2 regulates hormone sensing in mammary gland development and luminal breast cancer.

CPEB2 CPEB3

2.38e-052170232440535
Pubmed

Development of ET, primary myelofibrosis and PV in mice expressing JAK2 V617F.

DCC JAK2

2.38e-052170218033315
Pubmed

Differential Action of Reelin on Oligomerization of ApoER2 and VLDL Receptor in HEK293 Cells Assessed by Time-Resolved Anisotropy and Fluorescence Lifetime Imaging Microscopy.

VLDLR LRP8

2.38e-052170230873003
Pubmed

An emilin family extracellular matrix protein identified in the cochlear basilar membrane.

EMILIN2 THRB

2.38e-052170212837629
Pubmed

Heterozygous missense mutation in the rod cGMP phosphodiesterase beta-subunit gene in autosomal dominant stationary night blindness.

PDE6B RELA

2.38e-05217028075643
Pubmed

Sema3f Protects Against Subretinal Neovascularization In Vivo.

SEMA3F VLDLR

2.38e-052170228373097
Pubmed

The Reelin receptors Apoer2 and Vldlr coordinate the patterning of Purkinje cell topography in the developing mouse cerebellum.

VLDLR LRP8

2.38e-052170218301736
Pubmed

ZNRF proteins constitute a family of presynaptic E3 ubiquitin ligases.

ZNRF2 ZNRF1

2.38e-052170214561866
Pubmed

Identification and localization of a skeletal muscle secrotonin 5-HT2A receptor coupled to the Jak/STAT pathway.

HTR2A JAK2

2.38e-05217029169451
Pubmed

The association between serotonin-related gene polymorphisms and panic disorder.

HTR2A TPH2

2.38e-052170218436425
Pubmed

VLDLR and ApoER2 are receptors for multiple alphaviruses.

VLDLR LRP8

2.38e-052170234929721
Pubmed

JAK2-Mediated Phosphorylation of Stress-Induced Phosphoprotein-1 (STIP1) in Human Cells.

JAK2 STIP1

2.38e-052170235269562
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

EPRS1 COL5A2 DOCK11 PSMD11 LATS2 USP7 STIP1 GCN1 CLUH IPO11

2.94e-053991701037536630
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

DDX47 COL5A2 DOCK11 EPB41L3 VPS13D ARID2 USP7 GAN KIF2A TOP3B IPO11

3.65e-054971701136774506
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

EPRS1 MYH9 RAPH1 SWAP70 HEATR1 SND1 WDR20 GCN1

4.05e-05256170833397691
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

DDX47 MYH9 SWAP70 POLDIP3 OAS3 RELA PSMD11 PPA1 EPB41L3 NUP205 TOMM70 AP3S1 SND1 CD63 STIP1 GCN1 CLUH EIF3M IPO11

4.33e-0513671701932687490
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

CPEB2 DDX47 MYH9 DDX31 POLDIP3 RADX CPEB3 HEATR1 NOP14 SND1 CPEB4 PRMT1 GCN1 TOP3B

4.66e-058071701422681889
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

DDX31 TBC1D30 PPP1R12B RELA HEATR1 SRBD1 DICER1 NDUFV2 TOMM70 NOP14 SND1 WDR11 ARID2 WDR20 USP7 EHMT1 PRMT1 STIP1 KIF2A EIF3M

4.68e-0514971702031527615
Pubmed

Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family.

CDKN3 LZTR1 DOCK11 HEATR1 PPA1 NUP205 AP3S1 DCAF10 SND1 WDR11 PRMT1 STIP1 KIF2A CLUH EIF3M

5.73e-059311701527432908
Pubmed

The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome.

TRIM73 TRIM50 TRIM74

6.13e-0516170322792322
Pubmed

Proteome analysis of the HIV-1 Gag interactome.

EPRS1 MYH9 DICER1 SND1

6.42e-0544170425010285
Pubmed

Reelin together with ApoER2 regulates interneuron migration in the olfactory bulb.

VLDLR LRP8

7.10e-053170223209795
Pubmed

TPH2 -703G/T SNP may have important effect on susceptibility to suicidal behavior in major depression.

HTR2A TPH2

7.10e-053170219162119
Pubmed

The E3 ubiquitin ligase IDOL induces the degradation of the low density lipoprotein receptor family members VLDLR and ApoER2.

VLDLR LRP8

7.10e-053170220427281
Pubmed

Association of polymorphisms in HTR2A, HTR1A and TPH2 genes with suicide attempts in alcohol dependence: a preliminary report.

HTR2A TPH2

7.10e-053170221621273
Pubmed

Regulation of ApoE receptor proteolysis by ligand binding.

VLDLR LRP8

7.10e-053170215950758
Pubmed

Deubiquitination of NF-κB by Ubiquitin-Specific Protease-7 promotes transcription.

RELA USP7

7.10e-053170223267096
Pubmed

Functional consequences of hippocampal neuronal ectopia in the apolipoprotein E receptor-2 knockout mouse.

VLDLR LRP8

7.10e-053170218778775
Pubmed

Apelin is required for non-neovascular remodeling in the retina.

VLDLR PDE6B

7.10e-053170222067912
Pubmed

Phospholipid scramblase-1 regulates innate type 2 inflammation in mouse lungs via CRTH2-dependent mechanisms.

PLSCR1 IL7R

7.10e-053170237289545
Pubmed

Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells.

USP7 NLK

7.10e-053170230917315
Pubmed

IMPACT is a developmentally regulated protein in neurons that opposes the eukaryotic initiation factor 2α kinase GCN2 in the modulation of neurite outgrowth.

IMPACT GCN1

7.10e-053170223447528
Pubmed

CPEB4 is a cell survival protein retained in the nucleus upon ischemia or endoplasmic reticulum calcium depletion.

CPEB3 CPEB4

7.10e-053170220937770
Pubmed

C-Terminal Region Truncation of RELN Disrupts an Interaction with VLDLR, Causing Abnormal Development of the Cerebral Cortex and Hippocampus.

VLDLR LRP8

7.10e-053170228123028
Pubmed

Abnormal positioning of granule cells alters afferent fiber distribution in the mouse fascia dentata: morphologic evidence from reeler, apolipoprotein E receptor 2-, and very low density lipoprotein receptor knockout mice.

VLDLR LRP8

7.10e-053170211920707
Pubmed

Binding of purified Reelin to ApoER2 and VLDLR mediates tyrosine phosphorylation of Disabled-1.

VLDLR LRP8

7.10e-053170212670700
Pubmed

Fine mapping of a putative rd cDNA and its co-segregation with rd expression.

PDE6B AFP

7.10e-05317021974892
Pubmed

Global Analysis of CPEBs Reveals Sequential and Non-Redundant Functions in Mitotic Cell Cycle.

CPEB2 CPEB4

7.10e-053170226398195
Pubmed

Association between Serotonin-Related Polymorphisms in 5HT2A, TPH1, TPH2 Genes and Bipolar Disorder in Korean Population.

HTR2A TPH2

7.10e-053170220396435
Pubmed

Methylation of Smad6 by protein arginine N-methyltransferase 1.

BMPR1B PRMT1

7.10e-053170217118358
Pubmed

The Reelin receptors ApoER2 and VLDLR are direct target genes of HIC1 (Hypermethylated In Cancer 1).

VLDLR LRP8

7.10e-053170224076391
Pubmed

Up-regulation of ATP binding cassette transporter A1 expression by very low density lipoprotein receptor and apolipoprotein E receptor 2.

VLDLR LRP8

7.10e-053170222170052
Pubmed

Functional importance of covalent homodimer of reelin protein linked via its central region.

VLDLR LRP8

7.10e-053170221844191
Pubmed

MicroRNA-451 inhibits inflammation and proliferation of glomerular mesangial cells through down-regulating PSMD11 and NF-κB p65.

RELA PSMD11

7.10e-053170231652441
Pubmed

Antipsychotic-induced Hdac2 transcription via NF-κB leads to synaptic and cognitive side effects.

HTR2A RELA

7.10e-053170228783139
Pubmed

AP-3: an adaptor-like protein complex with ubiquitous expression.

AP3S1 AP3S2

7.10e-05317029118953
Pubmed

Type II transmembrane serine protease gene variants associate with breast cancer.

TMPRSS3 TMPRSS7

7.10e-053170225029565
Pubmed

Reelin controls neuronal positioning by promoting cell-matrix adhesion via inside-out activation of integrin α5β1.

VLDLR LRP8

7.10e-053170223083738
Pubmed

CPEB3 and CPEB4 in neurons: analysis of RNA-binding specificity and translational control of AMPA receptor GluR2 mRNA.

CPEB3 CPEB4

7.10e-053170217024188
Pubmed

Contributions of VLDLR and LRP8 in the establishment of retinogeniculate projections.

VLDLR LRP8

7.10e-053170223758727
Pubmed

ApoER2 function in the establishment and maintenance of retinal synaptic connectivity.

VLDLR LRP8

7.10e-053170221976526
Pubmed

Reelin and its receptors, VLDLR and ApoER2, in melanocytic nevi.

VLDLR LRP8

7.10e-053170228255385
Pubmed

Association analysis of TPH2, 5-HT2A, and 5-HT6 with executive function in a young Chinese Han population.

HTR2A TPH2

7.10e-053170221457069
Pubmed

Lats2 deficiency protects the heart against myocardial infarction by reducing inflammation and inhibiting mitochondrial fission and STING/p65 signaling.

RELA LATS2

7.10e-053170237497006
Pubmed

Evidence that Yih1 resides in a complex with ribosomes.

IMPACT GCN1

7.10e-053170222404850
Pubmed

Controlling autoimmune diabetes onset by targeting Protease-Activated Receptor 2.

PDE6B IL7R

7.10e-053170238653114
Pubmed

Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chain.

MYH9 RELA

7.10e-053170214508515
Pubmed

The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2.

VLDLR LRP8

7.10e-053170218039658
Pubmed

Loss of TET2 has dual roles in murine myeloproliferative neoplasms: disease sustainer and disease accelerator.

DCC JAK2

7.10e-053170225395421
Pubmed

The effects of SP110's associated genes on fresh cavitary pulmonary tuberculosis in Han Chinese population.

RELA SP110

7.10e-053170225612917
Pubmed

Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton.

VPS18 VPS41 CD63

7.42e-0517170314668490
InteractionALB interactions

MYH9 DDX31 MATN2 RNF181 DCC DICER1 NLRC4 TRIM23 LRP8 CDC45 RLF USP7 PRMT1 CACNA1I DMWD GCN1 WDTC1

3.76e-0839117017int:ALB
InteractionUBE2E1 interactions

RNF181 RELA ZNRF2 RNF43 TRIM23 USP7 ZNRF1 TRIM50 RNF111 IPO11

1.34e-0616417010int:UBE2E1
InteractionHSP90AA1 interactions

KLHL6 EPRS1 VPS18 MYH9 KLHL10 HSP90AB4P TRIM73 APAF1 DNAAF9 ACVR1C TRIM23 BLK JAK2 TOMM70 BMX LATS2 SND1 WDR20 VPS41 GAN PRMT1 STIP1 NLRP4 TRIM74 RNF111 PLCE1 WDTC1

7.38e-06126317027int:HSP90AA1
InteractionUBE2D4 interactions

TRIM35 RNF181 ZNRF2 RNF43 TRIM23 ZNRF1 TRIM50 RNF111

7.70e-061191708int:UBE2D4
InteractionUBE2E3 interactions

RNF181 ZNRF2 RNF43 USP7 ZNRF1 TRIM50 RNF111 IPO11

1.65e-051321708int:UBE2E3
InteractionCELSR3 interactions

SWAP70 PCDHGB1 GAN TOP3B CLUH

4.17e-05461705int:CELSR3
InteractionLZTR1 interactions

LZTR1 BMPR1B LIMS1 SND1 EHMT1 TOP3B PLSCR1

4.37e-051111707int:LZTR1
InteractionUBE2N interactions

RNF181 IMPACT PPA1 ZNRF2 RNF43 TRIM23 SND1 ZNRF1 STIP1 TRIM50 EIF3M RNF111

4.50e-0535117012int:UBE2N
InteractionAPBA2 interactions

RELA SP110 RNF43 LRP8 DMWD

5.14e-05481705int:APBA2
InteractionCOMTD1 interactions

EPRS1 HEATR1 NCAPG2 NUP205 TBC1D8 FBXL16 GCN1 TOP3B IPO11

5.19e-052001709int:COMTD1
GeneFamilyRing finger proteins

TRIM73 TRIM35 RNF181 RNF175 ZNRF2 RNF43 TRIM23 ZNRF1 TRIM50 TRIM74 RNF111

2.40e-062751211158
GeneFamilyBasic leucine zipper proteins|BTB domain containing

KLHL6 KLHL10 LZTR1 ZBTB8A MYNN GAN TNFAIP1

3.29e-051341217861
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM73 TRIM35 TRIM23 TRIM16 TRIM50 TRIM74

4.24e-0595121659
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

SWAP70 HEATR1 KDM5D SP110

3.74e-04511214870
GeneFamilyWD repeat domain containing

APAF1 LYST DCAF10 WDR11 WDR20 DMWD WDTC1 WDR72

3.84e-042621218362
GeneFamilyType 1 receptor serine/threonine kinases

ACVR1C BMPR1B

9.13e-0471212345
GeneFamilyActins|Deafness associated genes

MYH9 TBC1D24 TMPRSS3 PCDH15 GPSM2

9.75e-0411312151152
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TOMM70 GPSM2 STIP1 TTC22 WDTC1

1.06e-031151215769
GeneFamilyKelch like|BTB domain containing

KLHL6 KLHL10 GAN

2.78e-03421213617
GeneFamilyLow density lipoprotein receptors

VLDLR LRP8

3.30e-03131212634
GeneFamilyKinesins|Pleckstrin homology domain containing

STARD9 KIF2A KIF13A

3.60e-03461213622
GeneFamilyAT-rich interaction domain containing

KDM5D ARID2

4.41e-03151212418
GeneFamilyUbiquitin specific peptidases

USP44 USP7 USP3

6.26e-03561213366
GeneFamilyWD repeat domain containing|DDB1 and CUL4 associated factors

DCAF10 WDTC1

6.34e-03181212498
GeneFamilyF-box and leucine rich repeat proteins

FBXL19 FBXL16

8.58e-03211212558
GeneFamilyProteases, serine

TMPRSS13 TMPRSS3 TMPRSS7

8.67e-03631213738
CoexpressionGSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_UP

EPRS1 SWAP70 DOCK11 KDM5D CREB5 TBC1D24 PUS10 GNPAT AP3S2

5.93e-061971709M3136
CoexpressionAtlasDevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_k-means-cluster#5_top-relative-expression-ranked_1000

MYH9 TRIM35 DACH1 MYNN LATS2 ARID2 TSPAN8 USP7 ARHGAP29 KIF2A GCN1

1.83e-0622616711gudmap_developingKidney_e15.5_stage III -IV renal corpusc_1000_k5
ToppCellCV-Mild-7|Mild / Virus stimulation, Condition and Cluster

CPEB2 ATP13A4 TRIM73 HEATR1 ZNF619 ZBED5 NUP205 USP44 CPEB4

2.31e-081731709c9bbca9313a0fdf146c8c995624b94b937e818d8
ToppCell343B-Lymphocytic-ILC-ILC-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KLHL6 COL6A2 POLR3H PSMD11 HEATR1 TBC1D24 NUP205 TNFAIP1 CLUH

5.67e-081921709445985fe1bcd33e4f0a1704b27988fbfc9334538
ToppCellCV-Mild-7|CV / Virus stimulation, Condition and Cluster

ATP13A4 TRIM73 HEATR1 ZNF619 ZBED5 NUP205 USP44 CPEB4

3.07e-07170170825ebde7d2f8ae1afdfaf5876284ff20bb179eb10
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

VLDLR COL6A2 BMX VPS41 GPSM2 IPO11 PLCE1 WDTC1

9.01e-071961708a31e227de2dc077b81881295b012d22fedbd65ed
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

VLDLR COL6A2 BMX VPS41 GPSM2 IPO11 PLCE1 WDTC1

9.01e-071961708b04ca69b0ed44e09c989b575f747e1e819cd8008
ToppCelldroplet-Spleen-SPLEEN|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN3 KDM5D NCAPG2 CDC45 AP3S1 CD63 GPSM2

4.50e-061721707d32731a56e113ff0ef7167b23959d69baf2068f9
ToppCellfacs-MAT-Fat-18m-Lymphocytic-T_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR2A TDRD9 RNF43 LRP8 BMPR1B ZNRF1 IL7R

4.67e-06173170797391a763c17ce0107c9e2386e88c417ac75a72e
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RADX MATN2 NCAPG2 CREB5 LRP8 BMPR1B AFP

6.75e-06183170742dc31d587fbb9724b2f0be5ee8ed77233f67b86
ToppCellCV-Healthy-7|CV / Virus stimulation, Condition and Cluster

OAS3 CCDC88C LATS2 WDR11 GAN TOP3B RNF111

7.00e-0618417070e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN3 EMILIN2 PHYHIP NCAPG2 CDC45 TSPAN8 GPSM2

7.51e-0618617077cdcf507a9a1349ed2cf62b79116367c3fc732dd
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN3 EMILIN2 PHYHIP NCAPG2 CDC45 TSPAN8 GPSM2

7.51e-061861707ac6e32cf07f0f013101ca7aedae0c562857f182b
ToppCell343B-Lymphocytic-ILC-ILC-1|343B / Donor, Lineage, Cell class and subclass (all cells)

KLHL6 PSMD11 HEATR1 TBC1D24 NUP205 TNFAIP1 CLUH

8.05e-0618817078f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCell343B-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KLHL6 COL6A2 HEATR1 TBC1D24 NUP205 TNFAIP1 CLUH

8.33e-061891707c26428871dc3261327d89cacaba6e21e004ff1f3
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL5A2 COL6A2 AOX1 DCC PCDH15 GPSM2 FAM20A

8.93e-061911707b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

AOX1 HKDC1 DCC EPB41L3 CREB5 PCDH15 WDR72

8.93e-0619117071c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

AOX1 HKDC1 DCC EPB41L3 CREB5 PCDH15 WDR72

8.93e-0619117073c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

EPRS1 LZTR1 DNAAF9 TRIM23 GPR107 TBC1D8 DMWD

1.20e-0520017071fa8422fd820d21e285a7e7c4c6fbd8b7277d2af
ToppCellLPS_IL1RA-Endothelial-Endothelial-Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DACH1 TSPAN8 ARHGAP29 KIF2A LY6H KIF13A IL7R

1.20e-0520017077034f57e282982c19c13ee8ab78eabaffa069e30
ToppCell15-Trachea-Immune-Immune|Trachea / Age, Tissue, Lineage and Cell class

DDX47 CDKN3 EMILIN2 NCAPG2 NLRC4 CDC45

2.09e-051461706ca722a89c6601e78f253d9484d01931f26161820
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 RNF175 DCC BLK CCDC88C RABIF

2.43e-05150170617da17f01a3d41ac7df20f806e3eae30eca06982
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 RNF175 DCC BLK CCDC88C RABIF

2.43e-0515017068702d5bb419d5e997d388e8f7e0365ba5d1de8d5
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 RNF175 DCC BLK CCDC88C RABIF

2.43e-0515017068b781ec3e6c2adf052d46d724e2aef72b0c27d13
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Basophil|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KLHL6 EMILIN2 RNF43 AP3S1 CD63 IL7R

4.01e-051641706dc22b1fef49c1557a0b63c536eaba574dfcab715
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KLHL6 EMILIN2 RNF43 AP3S1 CD63 IL7R

4.01e-051641706f4de9f18134a06f3d7fcf5b50b8e21c1506e2083
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

DDX31 MATN2 EPB41L3 NCAPG2 TBC1D24 CD63

4.58e-0516817062fb2d916eb5000a637240d38e47a9b4f61f9f83f
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL5A2 VLDLR COL6A2 HTR2A MATN2 CD63

4.74e-051691706031465190cd3623a25ef2b868daab8d932c8ff08
ToppCellwk_20-22-Epithelial-Proximal_epithelial-intermediate_neuroendocrine|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ACVR1C USP44 FBXL16 TMPRSS3 LY6H UNC79

5.06e-051711706b7cddb8f726a43fb8a37f3e67a3f722e2178fd7a
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DACH1 OAS3 LYST RLF BMX CPEB4

5.23e-051721706d354424c1f861b6607dfd63b9724f4c237b30275
ToppCelldroplet-Lung-1m-Hematologic-myeloid-Basophil/Mast_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CPEB2 ACVR1C RNF43 CD63 TMPRSS7 IL7R

5.40e-051731706117163c5cd2b7aaa1c0682c8ac44b4249df4d2f8
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMILIN2 ACVR1C RNF43 LRP8 JAK2 CD63

5.40e-0517317063612772632ddf11eb48579cae9a8ccab6b3f1f52
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EMILIN2 ACVR1C RNF43 LRP8 JAK2 CD63

5.40e-0517317064dc261ebcdb9bdcfca1451da1bd254f0dc5de203
ToppCellEndothelial-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

REP15 BMX ARHGAP29 SCGB2B2 IPO11 PLCE1

5.40e-051731706a81992965137195d20fc498f750975303961a828
ToppCelldroplet-Lung-1m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CPEB2 ACVR1C RNF43 CD63 TMPRSS7 IL7R

5.40e-05173170601df9baeedf30e3a4891738554cdd300394dbb96
ToppCellpdx-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

AOX1 DNAAF9 THRB CPEB4 TRIM50 GNPAT

5.94e-0517617061e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DACH1 LYST CCDC88C ARHGAP5 CPEB4 ARHGAP29

6.32e-05178170601dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellPND28-Immune-Immune_Myeloid-Megakaryocyte/Platelet|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH9 LIMS1 KATNBL1 KIF2A NLK IPO11

6.52e-051791706362c003503190dc272fa89185a83a65e063d7a67
ToppCellPND28-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH9 LIMS1 KATNBL1 KIF2A NLK IPO11

6.52e-051791706e0eec8d48868c76c3e879f219357c62ceff1bc76
ToppCellPND28-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH9 LIMS1 KATNBL1 KIF2A NLK IPO11

6.52e-0517917067d2e6bde00a9ab4cb21bd48b140ce205e36f9d77
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DACH1 BMPR1B TSPAN8 GPSM2 USP3 WDR72

6.72e-051801706cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A2 COL6A2 DACH1 BMPR1B STARD9 HHIPL1

6.72e-051801706280ff5c8f292be1b88120db5ff1788b750644856
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A2 COL6A2 DACH1 BMPR1B STARD9 HHIPL1

6.72e-051801706fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL5A2 VLDLR COL6A2 THBS4 CD63 LY6H

6.93e-051811706e1ae9ada60ec89e7a7cde9c231c1a099ed2ffecc
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-club_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMPRSS13 RNF43 BMPR1B AFP CD63 TTC22

6.93e-0518117064a0f1b121570430afb100c589657d931184e124f
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-club_cell-club_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMPRSS13 RNF43 BMPR1B AFP CD63 TTC22

6.93e-05181170634b49092f71128898af3b311170c4ed8adfefcff
ToppCellfacs-Lung-EPCAM-18m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS13 RNF43 BMPR1B AFP CD63 TTC22

7.15e-0518217066685a0abd9c3a79d03b6a578e5d7fa86a9d74117
ToppCellfacs-Lung-EPCAM-18m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS13 RNF43 BMPR1B AFP CD63 TTC22

7.15e-051821706f8eb35eb7f2b8ad47d527ae9ff8a9ddbcd2eedce
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DACH1 CREB5 THRB ZNRF1 KIF13A IL7R

7.37e-051831706e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCellCV-Healthy-7|Healthy / Virus stimulation, Condition and Cluster

OAS3 LATS2 WDR11 GAN TOP3B RNF111

7.82e-0518517061979d189c204f4c2893e3170a514ee7d5523406c
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KLHL6 DCC CCDC88C SND1 CPEB4 EHMT1

7.82e-0518517063b77bc49cd3740acc025e162a36282ac09e12198
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

COL5A2 COL6A2 MATN2 DCC STARD9 PCDH15

8.30e-05187170613731298bc562ec29582f5da1b4c97261284f6f1
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RAPH1 EMILIN2 FBXL19 EPB41L3 LATS2 KIF13A

8.30e-0518717065917bdfe84cf5941e21b415aebbab3090cc5d576
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN3 PHYHIP NCAPG2 CDC45 TSPAN8 GPSM2

8.30e-051871706dceca7ae3dae96078cccc17a0d8a61b06fa6dffb
ToppCellCOVID-19-kidney-CD-IC-B|kidney / Disease (COVID-19 only), tissue and cell type

DACH1 BMPR1B LIMS1 TSPAN8 GPSM2 WDR72

8.30e-051871706ce05b89860573fe0356102e2998d1ef6d1968034
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL5A2 COL6A2 AOX1 PCDH15 GPSM2 FAM20A

8.80e-051891706e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL5A2 COL6A2 AOX1 PCDH15 GPSM2 FAM20A

8.80e-0518917062a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL5A2 COL6A2 AOX1 DCC PCDH15 GPSM2

9.06e-051901706841cd55861b43578d704418b9bc0af2e8b88323a
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL5A2 COL6A2 AOX1 PCDH15 GPSM2 FAM20A

9.06e-051901706d60395739458d7f47a3350ade751fe3819500320
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL5A2 COL6A2 AOX1 DCC PCDH15 GPSM2

9.59e-0519217063d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL5A2 COL6A2 AOX1 DCC PCDH15 GPSM2

9.59e-0519217066f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL5A2 COL6A2 AOX1 PCDH15 GPSM2 FAM20A

9.59e-051921706f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCellfacs-Aorta-Heart-3m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A2 VLDLR COL6A2 EMILIN2 CD63 PLCE1

9.59e-0519217060dc1f46e40346ed0b286e53b106a812441575100
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DACH1 THRB ARHGAP29 ZNRF1 KIF13A IL7R

9.87e-051931706a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCellRV-10._Endothelium_II|World / Chamber and Cluster_Paper

RAPH1 BMPR1B BMX PCDH15 ARHGAP29 PLSCR1

9.87e-0519317062531266bc57339d4e2b22a88817008e32b8c1598
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

RAPH1 BMPR1B BMX PCDH15 ARHGAP29 PLSCR1

9.87e-05193170601c2df9206f1527c578e808978e58196c35e72f5
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL5A2 COL6A2 AOX1 DCC PCDH15 GPSM2

9.87e-051931706fb28717fadd06c3840636d25409ce80c9254bd34
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL5A2 COL6A2 AOX1 DCC PCDH15 GPSM2

1.02e-04194170689b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL5A2 COL6A2 AOX1 DCC PCDH15 GPSM2

1.02e-04194170660622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell18-Distal-Mesenchymal-Mesenchyme_SERPINF1-high|Distal / Age, Tissue, Lineage and Cell class

COL5A2 COL6A2 MATN2 TSPAN8 CD63 LY6H

1.04e-041951706f86737bff21d81673238813df61a15cfe88d0b15
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A2 COL6A2 MATN2 DACH1 BMPR1B HHIPL1

1.04e-041951706803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A2 COL6A2 MATN2 DACH1 BMPR1B HHIPL1

1.04e-0419517064f70157d42a16ff0259bc24a62803c4df4285c44
ToppCellASK428-Epithelial-Transformed_epithelium|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

SEMA3F COL5A2 COL6A2 DOCK11 NLRC4 ARHGAP29

1.04e-041951706c750602c765a51075ba6ede78e3ba80b62374481
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN3 NCAPG2 CDC45 TMPRSS3 GPSM2 IL7R

1.04e-041951706294c74336fafc1bad237d851efb4a487475078eb
ToppCell(1)_Osterolineage_cells-(11)_OLC-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

COL5A2 COL6A2 MATN2 TSPAN8 CD63 GPSM2

1.04e-04195170678978d85273e5463a7f43e4c121e647fa6aba42b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 DOCK11 EMILIN2 ADCY7 BLK IL7R

1.04e-0419517067b6c69df943842b566a596e30bb50dbe80dccc83
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDKN3 NCAPG2 CDC45 TMPRSS3 GPSM2 IL7R

1.04e-0419517065749ea833be84e262e3d0a4fe1a9a373f0ef545f
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A2 COL6A2 MATN2 PPP1R12B DACH1 BMPR1B

1.07e-0419617062b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A2 VLDLR COL6A2 EMILIN2 CD63 PLCE1

1.07e-0419617062029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL5A2 VLDLR COL6A2 MATN2 PHYHIP CREB5

1.10e-0419717062744cc94883c5d0424677cf5093bbab622933e9b
ToppCellURO-Myeloid-cDC2|URO / Disease, Lineage and Cell Type

PPA1 NDUFV2 ARHGAP5 PRMT1 PLSCR1 EIF3M

1.10e-0419717067fee14356d7fba68a0515c8b9284568d14124b0a
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|lung / Disease (COVID-19 only), tissue and cell type

KLHL6 DOCK11 EMILIN2 EPB41L3 ADCY7 NLRC4

1.10e-0419717063896729740d151f0eb845f1961c7b969bfbdd28d
ToppCellCOVID-19_Severe-Classical_Monocyte|World / disease group, cell group and cell class

EMILIN2 OAS3 CREB5 KIF13A FAM20A PLSCR1

1.10e-041971706344801997b89bd81d8d5c3c872934de523233a8d
ToppCellInfluenza-Influenza_Severe-Lymphocyte-T/NK-CD4+_Tcm|Influenza_Severe / Disease, condition lineage and cell class

MATN2 HKDC1 ACVR1C FBXL16 CACNA1I IL7R

1.14e-041981706fc99f2e300d76126d05c0c43e11cdbbeb74f6f0d
ToppCellBLOOD--(3)_MNP-(3)_Intermediate_monocytes|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PPA1 EPB41L3 AP3S1 CD63 PLSCR1 EIF3M

1.14e-04198170670c3efd4f6026a6a6065be632160a265d9ecd1e4
ToppCellcontrol-HLA-DR+_CD83+_Monocyte|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

EMILIN2 OAS3 EPB41L3 NLRC4 JAK2 PLSCR1

1.17e-041991706f1b370d2869ad29c9d8ff41fdcc486fffa781ee2
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

PPA1 NCAPG2 RNF43 LRP8 STIP1 SPINDOC

1.17e-041991706cdcdef1d95a8e476de016b1e11ee010438834be0
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

DDX31 PPA1 NCAPG2 LRP8 CDC45 SND1

1.17e-04199170685b3b1ad01368dae4adbc9da7efc148e49992f69
ToppCell(5)_Fibroblast-D|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

COL5A2 COL6A2 MATN2 AOX1 PHYHIP TSPAN8

1.17e-0419917063f415620ad8b8d8c6871e1353e13f87b281fcc0e
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

PPP1R12B NDUFV2 LIMS1 ANKRD18A KIF2A EIF3M

1.17e-041991706a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellTCGA-Colorectal-Primary_Tumor|TCGA-Colorectal / Sample_Type by Project: Shred V9

DDX31 PPA1 NCAPG2 LRP8 CDC45 SND1

1.17e-041991706c7d6a8398f2419b726a0461585d1ee0561654e3b
ToppCell343B-Fibroblasts-Fibroblast-F|343B / Donor, Lineage, Cell class and subclass (all cells)

COL5A2 COL6A2 AOX1 PHYHIP TSPAN8 GPSM2

1.17e-041991706b877c1d24357249781032e99d4237f72789cc9b8
ToppCellSepsis-Leuk-UTI-Lymphocyte-T/NK-CD8+_T_naive|Leuk-UTI / Disease, condition lineage and cell class

CDKN3 KLHL10 THNSL1 KIF2A GPRASP2 IL7R

1.17e-041991706476daaa0b764f82a0dfb85cc94e5b07a091703bd
ToppCell343B-Fibroblasts-Fibroblast-F-|343B / Donor, Lineage, Cell class and subclass (all cells)

COL5A2 COL6A2 AOX1 PHYHIP TSPAN8 GPSM2

1.17e-041991706e32fa66f3361474088ba1dd58574822537950d59
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

COL5A2 COL6A2 DOCK11 PPP1R12B DMWD PLCE1

1.20e-042001706b5b5a32925f225610fe25a021a742d6397162863
ToppCellTransverse-(2)_B_cell-(24)_B_cell_cycling|Transverse / shred on region, Cell_type, and subtype

CPEB2 CDKN3 CREB5 CDC45 NLK RNF111

1.20e-042001706e3f9736227151f23f0e331eec0a7a15ce464b517
ToppCellTransverse-B_cell-B_cell_cycling|Transverse / Region, Cell class and subclass

CPEB2 CDKN3 CREB5 CDC45 NLK RNF111

1.20e-0420017060e270f8019d9f22068ca426d661937262a5cd331
ToppCellSigmoid-(3)_ILC|Sigmoid / shred on region, Cell_type, and subtype

MATN2 DACH1 BMX IL7R TRIM74 WDR72

1.20e-042001706a7326c43987a5eb4f4f5b48c4252cf4870432e5d
ToppCellSigmoid-ILC-ILC|Sigmoid / Region, Cell class and subclass

MATN2 DACH1 BMX IL7R TRIM74 WDR72

1.20e-0420017064ac1e6d7f358003e2448eb69e545772cd261c55f
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_only / Treatment groups by lineage, cell group, cell type

COL5A2 COL6A2 SWAP70 DOCK11 STARD9 PLCE1

1.20e-04200170669edc375d85689300d1dbc1217fedc40063ecdcb
ToppCellsevere-CD163+_Monocytes_(Sample_ID1_d7)|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TDRD9 EMILIN2 OAS3 CREB5 KIF13A PLSCR1

1.20e-042001706a3f22826f3d8f917ff0594bdadd93b60763bcaa2
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

APAF1 LYST CREB5 BMX CPEB4 PLSCR1

1.20e-042001706808571d74bb5c4d765ff13fc9393f88020d4e90d
DiseaseMajor depressive disorder

HTR2A TPH2

8.95e-0531622cv:C1269683
DiseaseMAJOR DEPRESSIVE DISORDER

HTR2A TPH2

8.95e-0531622608516
Diseasehydantoin-5-propionate measurement

AOX1 AMDHD1

1.78e-0441622EFO_0800051
DiseaseNoonan syndrome (implicated_via_orthology)

LZTR1 APAF1

1.78e-0441622DOID:3490 (implicated_via_orthology)
DiseaseSchizophrenia

VLDLR HTR2A RELA DCC DICER1 ADCY7 NDUFV2 LRP8 WDR11 TPH2 TSPAN8 KIF2A TOP3B GNPAT

3.85e-0488316214C0036341
DiseaseUlcerative Colitis

RELA ADCY7 JAK2 IL7R

4.05e-04631624C0009324
DiseaseMajor Depressive Disorder

HTR2A RAPH1 APAF1 ADCY7 NDUFV2 LRP8 TPH2

4.07e-042431627C1269683
DiseaseCarcinoma, Lobular

MYH9 PPP1R12B

4.43e-0461622C0206692
DiseaseUnipolar Depression

HTR2A RAPH1 APAF1 ADCY7 NDUFV2 LRP8 TPH2

5.95e-042591627C0041696
Diseasereticulocyte count

SEMA3F CDKN3 EPRS1 MYH9 KLHL10 SWAP70 DNAAF9 ACVR1C TBC1D8 CCM2 THRB DCAF10 WDR20 CPEB4 USP3

6.71e-04104516215EFO_0007986
Diseasesensorineural hearing loss (is_implicated_in)

MYH9 TMPRSS3 GPSM2

7.85e-04331623DOID:10003 (is_implicated_in)
DiseaseNonsyndromic genetic hearing loss

MYH9 TMPRSS3 PCDH15 GPSM2

8.26e-04761624cv:C5680182
DiseaseDepression, Bipolar

HTR2A NDUFV2 STARD9 TPH2

9.55e-04791624C0005587
DiseaseLiver Cirrhosis, Experimental

CDKN3 COL5A2 COL6A2 APAF1 RELA JAK2 AP3S1 AFP TSPAN8 CD63 PLSCR1 IL7R

1.22e-0377416212C0023893
Diseasecolon cancer (biomarker_via_orthology)

APAF1 JAK2 MUC2

1.28e-03391623DOID:219 (biomarker_via_orthology)
Diseasegastric adenocarcinoma (is_implicated_in)

RNF43 PLCE1

1.59e-03111622DOID:3717 (is_implicated_in)
Diseasebirth weight

VLDLR HKDC1 ACVR1C DCC ADCY7 LIMS1 SND1 PLCE1

1.69e-033991628EFO_0004344
Diseasedementia (is_implicated_in)

VLDLR LRP8

1.91e-03121622DOID:1307 (is_implicated_in)
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

TMPRSS3 PCDH15 GPSM2

2.79e-03511623cv:CN043650
Diseasehepatocellular carcinoma (is_implicated_in)

CDKN3 LZTR1 DICER1 RNF43 ARID2

3.31e-031811625DOID:684 (is_implicated_in)
Diseasephenylalanine measurement

VPS18 PCDH15 KIF13A

3.46e-03551623EFO_0005001
DiseaseEye Abnormalities

APAF1 BMPR1B

3.86e-03171622C0015393
Diseasemajor depressive disorder (is_implicated_in)

HTR2A TPH2

3.86e-03171622DOID:1470 (is_implicated_in)
Diseasehyperglycemia (implicated_via_orthology)

HTR2A HKDC1

3.86e-03171622DOID:4195 (implicated_via_orthology)
DiseaseAmelogenesis imperfecta

FAM20A WDR72

3.86e-03171622cv:C0002452
Diseasemean platelet volume

SEMA3F MYH9 DOCK11 PCDHGB1 RTTN ANKMY1 JAK2 LIMS1 CPEB4 USP7 STIP1 KIF2A PLCE1

4.25e-03102016213EFO_0004584
Diseasecolorectal cancer (is_implicated_in)

DCC DICER1 RNF43 ARID2

4.52e-031211624DOID:9256 (is_implicated_in)
Diseaseprion disease

CPEB4 ADAMTS14

4.82e-03191622EFO_0004720

Protein segments in the cluster

PeptideGeneStartEntry
LEIKAHEDEVLCCAF

APAF1

651

O14727
TNCCLELDDEGKVIK

ERV3-1

571

Q14264
FKDLGVTDVLCEACD

DDX47

26

Q9H0S4
SQEEACAIVLLECGA

ANKRD18A

111

Q8IVF6
RVLFIKDVIGDEICC

TNFAIP1

196

Q13829
VLFCGTEVIQAKAAC

ATP13A4

346

Q4VNC1
IVDVGDQKTSVCCVE

ACTR8

281

Q9H981
NCLVDRDLCVKVSDF

BMX

541

P51813
AVICKESCNEDVIGA

HTR2A

346

P28223
VKKCETCAIADLGLA

ACVR1C

331

Q8NER5
LCKAEDNGVLICEYV

ARID2

381

Q68CP9
TLDKCFENVCELDLI

AP3S2

96

P59780
NELFCSKIELCEEHG

C14orf28

191

Q4W4Y0
ESKVAAEELCCLLGQ

CCM2

201

Q9BSQ5
FYTECDVNKEGLECL

ADCY7

891

P51828
TLDKCFENVCELDLI

AP3S1

96

Q92572
DKSIADCVEALLGCY

DICER1

1556

Q9UPY3
CCIADLGLAVKFISD

BMPR1B

346

O00238
AKVASFTVEGCELIC

DACH1

196

Q9UI36
FLEDCIITACQEGLI

DMWD

611

Q09019
CELICQSADTGDVVF

ADAMTS14

646

Q8WXS8
IDLDFKGQLCELSCS

PRMT1

351

Q99873
DKVFCVGQLVCAVLA

AOX1

666

Q06278
AVCLLCGEAGKEDTV

FBXL19

86

Q6PCT2
KEVLLEECFCGSSVT

RAPH1

381

Q70E73
KDSLFLVDLLCCGAI

GPR107

401

Q5VW38
EYVAEEICIAASKAC

JAK2

61

O60674
CVCGDENILVQEFVK

JAK2

616

O60674
KLMAGFVECLDCEDA

NUP205

946

Q92621
ENCICDVIGLLVFVG

RADX

371

Q6NSI4
VEVLGIVFACCLVKS

CD63

216

P08962
LKNCEEVGLFSELDC

CREB5

66

Q02930
GCQLIKFDSVEVCVC

FAM189A1

126

O60320
AIEGKDAVLECCVSG

DCC

251

P43146
EEKQYISLGCCVDLL

KATNBL1

206

Q9H079
TLKVLGNFDEAIVCC

GPSM2

111

P81274
GCTKDERFVAEVTCL

KLHL6

326

Q8WZ60
VCQCSEGFLINEDLK

MATN2

466

O00339
QFCDVEFVLGEKEEC

LZTR1

441

Q8N653
DGLGCESCNVLAVEK

LPAR2

261

Q9HBW0
ICCEKVEQDAARGII

NLRC4

41

Q9NPP4
ADAKGCLQLCLEEVA

HHIPL1

176

Q96JK4
IGAFGEVCLACKVDT

LATS2

676

Q9NRM7
ICDIIGECKEQVANS

HSP90AB4P

391

Q58FF6
AVGLCQSFCELLKEI

IPO11

726

Q9UI26
DLAQIIEACDVCLKE

EIF3M

41

Q7L2H7
YLCDVEDCEALGALV

FRMD8P1

161

Q9BZ68
ICQVCSRGDEDDKLL

KDM5D

316

Q9BY66
VGNIKFLVCADCEIG

RABIF

86

P47224
LVLGCAVQCERKEEF

CCDC88C

126

Q9P219
VCSCCGDVDFEIKSL

PLSCR1

236

O15162
KICGRKLECALEFET

PCDHGB1

91

Q9Y5G3
VCDVSVGLICKNEDQ

MUC2

1841

Q02817
FSDLECTELDLVKCG

PDE6B

506

P35913
RLLGFDKQCSELVDC

DCAF10

496

Q5QP82
GVSCCELAEEDFLAV

NSUN5P2

91

Q63ZY6
KQREAGFLCDCTIVI

MYNN

16

Q9NPC7
FEICGALVEVKCLNF

IL7R

71

P16871
CAFAEQEEVDVLLCA

GCN1

1076

Q92616
DLKITDVIIGFQACC

MYH9

776

P35579
LCLVKCFITAAGCED

NLRP4

841

Q96MN2
CVLKICDFGLARVEE

NLK

276

Q9UBE8
EDILCVLTRDDCFKG

DDX31

656

Q9H8H2
QDVVKGLFVCCLFLE

NOP14

586

P78316
DDCAKIFCIRISDDI

IMPACT

31

Q9P2X3
GFINSGILKVDVDCC

LY6H

91

O94772
CVEDVLKLIDIGNSC

KIF2A

406

O00139
FEICLGQYDDDCKLA

PCDH15

21

Q96QU1
VCLGILQEFCEKDFI

PUS10

111

Q3MIT2
VVFQGVECEECLLVC

ARHGAP29

631

Q52LW3
DVDALCACKILQALF

CDC45

26

O75419
CEIFNELRLEGKLCD

KLHL10

26

Q6JEL2
ESKGCIYLDACIDVV

DOCK11

216

Q5JSL3
LIDACIEEDGKLYLC

CPEB2

391

Q7Z5Q1
FEEGCYLLCKSEAIQ

GNPAT

536

O15228
IDACLEEDGKLYLCV

CPEB3

501

Q8NE35
DLKTLCCEFLEGCIA

GAN

116

Q9H2C0
ILVSEALCCKIADFG

BLK

366

P51451
DCLSDRCKILQVFDD

CACNA1I

106

Q9P0X4
LKEQGRECCLSKDDV

CACNA1I

286

Q9P0X4
DCEKRCGALDVVFVI

COL6A2

606

P12110
QECYLVFIGCSLKED

DNAAF9

1061

Q5TEA3
LLLDCGADVNKCSDE

ANKMY1

311

Q9P2S6
NGAILCDKIECQDVL

COL5A2

66

P05997
DSQCCSFKLLVEEEG

LYST

1206

Q99698
ETFEEIIDCSGKCIL

AMDHD1

66

Q96NU7
DVCEIGSKVCARGEI

PPA1

121

Q15181
LIDACIEEDGKLYLC

CPEB4

531

Q17RY0
DVCIADGVCIDAFLK

SPAM1

456

P38567
LEEVGKTENCIIDCL

HEATR1

1886

Q9H583
VISELDACKECTQGV

EMILIN2

681

Q9BXX0
AKEVLDCYGCVDILI

DHRS7C

111

A6NNS2
ELKSCGIQDIFVFCT

CDKN3

66

Q16667
SGCVDIAEILLAAKC

EHMT1

916

Q9H9B1
QCKVILLDGSEYTCD

EPB41L3

111

Q9Y2J2
VIADFSGLLEKCCQG

AFP

571

P02771
FQLLDQKTCGDIDEC

LRP8

366

Q14114
VTEEDIVELFCVCGA

POLDIP3

291

Q9BY77
GCDVELIIFLNCFTD

OAS3

471

Q9Y6K5
GVANVFLECLFCDVK

KIF13A

791

Q9H1H9
FCLVGVSDLDICEFI

FBXL16

171

Q8N461
EDCSVVTEVGALFCL

RTTN

936

Q86VV8
GQLSLFCLEDKELLC

TRIM35

106

Q9UPQ4
KIVQIPFCGEIDCED

EPRS1

1441

P07814
IEECVLSGKDVNGEC

SEMA3F

101

Q13275
DCEECIQLEPTFIKG

STIP1

416

P31948
QAELKCPVCLLEFEE

RNF181

71

Q9P0P0
VFGCLDECLIIAAAL

TDRD9

616

Q8NDG6
TCEDSIVVKEVCGAV

HKDC1

811

Q2TB90
CGVFLKELCEVLDGA

PLCE1

706

Q9P212
DEKALLGACDCTQIV

FAM20A

201

Q96MK3
CIQCELKIGSEEFEE

GPRASP2

586

Q96D09
AATGQEVELCLECIE

PSMD11

101

O00231
VCAICLEEFSEGQEL

RNF43

271

Q68DV7
KETCLITFLLAGIEC

SND1

546

Q7KZF4
EGAALDCFEVTLKCE

SPINDOC

6

Q9BUA3
CNKFLTCSVEDGELV

PHYHIP

261

Q92561
NVGLCICLFDITKLE

POLR3H

41

Q9Y535
FLEDCIVTACQEGFI

WDR20

541

Q8TBZ3
CVEFIEDTGLCTEGL

ARHGAP5

1281

Q13017
ICEGLFVREKDCASL

STARD9

126

Q9P2P6
RCDLCQEVLADIGFV

LIMS1

96

P48059
GELLKRKNSDECEVC

SP110

526

Q9HB58
ECVSFVGVDINICSE

SRBD1

701

Q8N5C6
LKACVASNDIEGIVC

NCAPG2

1066

Q86XI2
EEVELCSSVECKGII

CLUH

541

O75153
IDEAECFEKACRILA

TBC1D24

146

Q9ULP9
IELIARCDGVSDCKD

TMPRSS3

86

P57727
LSLFCEKDQELICGL

TRIM74

96

Q86UV6
LDCDKEGENICFEVL

TOP3B

116

O95985
KDIFGDACDNCLSVL

THBS4

536

P35443
VCIIDGLCYVEGDKN

VWDE

1056

Q8N2E2
DLTEYCGQLVEAKCL

WDTC1

176

Q8N5D0
VLSKDAGECAICLEE

ZNRF2

191

Q8NHG8
DVFCDCSILVEGKVF

ZBTB8A

21

Q96BR9
DCKLKSDELGCVRFD

TMPRSS13

216

Q9BYE2
CKEVLDIICNLESEG

RLF

276

Q13129
KCTICLSILEEGEDV

RNF111

941

Q6ZNA4
FCEDCVAAILKDSIQ

TMPRSS7

191

Q7RTY8
ICAVCGQKIIVELDE

RNF175

226

Q8N4F7
VEESLGKCCLVTEEI

TBC1D8

536

O95759
LDELVAAECVYCGEL

VPS18

936

Q9P253
LDKDELCVVCGDKAT

THRB

101

P10828
LDKLICGCEDGTIII

WDR72

416

Q3MJ13
GQKLGCCVIDVDDDI

THNSL1

76

Q8IYQ7
CLEDVTAVCILEGFQ

TOMM70

206

O94826
KLGEQIECCETADEF

TBC1D30

471

Q9Y2I9
DKLEEFCNLIGEDCL

REP15

146

Q6BDI9
KGVLVDEENICESCL

VPS41

781

P49754
VEIFVDCECGKTEFN

TPH2

106

Q8IWU9
DCECGKTEFNELIQL

TPH2

111

Q8IWU9
EVNCLICGTESRKFD

USP3

321

Q9Y6I4
EELVCRLKICDGFSL

ZBED5

261

Q49AG3
LSLFCEKDQELICGL

TRIM73

96

Q86UV7
EGKEVLCDFCLDDTR

TRIM16

71

O95361
KGDILLDENCCVESL

SWAP70

251

Q9UH65
FLELCELVAELCSQK

nan

41

Q9H521
VKVLECGVCEDVFSL

TRIM23

26

P36406
CGVCEDVFSLQGDKV

TRIM23

31

P36406
GVQLLCLIDKAADAC

WDR11

1066

Q9BZH6
CSVQLGDACLDIDKL

SCGB2B2

16

Q4G0G5
CLGGDEIFLLCDKVQ

RELA

206

Q04206
ICNIRCLEKVDAFEE

TPMT

211

P51580
LSLFCEKDQELICGL

TRIM50

96

Q86XT4
LACAKADLEEVVRVC

TTC22

366

Q5TAA0
DAGELCKCDFLVSIS

ZNF619

16

Q8N2I2
GCVRDLLEECKKAVE

USP7

916

Q93009
EEATLGAFLICELCQ

SSU72

146

Q9NP77
ETEALEGKIYVCDQC

USP44

526

Q9H0E7
VLTKDAGECVICLEE

ZNRF1

176

Q8ND25
AIIVFQEEFKCCGLV

TSPAN8

141

P19075
ECGAEELVCAVEAVI

UNC79

436

Q9P2D8
LCLCLDFQFDTVVKD

UNC79

1126

Q9P2D8
FELIDRKTCGDIDEC

VLDLR

386

P98155
ISGVEIKAESVCICF

VPS13D

2701

Q5THJ4
FLCEVKLAFKCDGEI

L1TD1

276

Q5T7N2
GVKEACSILAEALCD

PPP1R12B

261

O60237
DKLFTLIEVECLGAC

NDUFV2

166

P19404