Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmicrotubule plus-end binding

APC PAFAH1B1 MLPH

1.86e-04221023GO:0051010
GeneOntologyMolecularFunctioncytoskeleton-nuclear membrane anchor activity

SYNE1 SUN1

2.56e-0451022GO:0140444
GeneOntologyBiologicalProcessprotein localization to microtubule cytoskeleton

MAP1A APC CEP63 CEP72 GOLGB1

1.14e-05591035GO:0072698
GeneOntologyBiologicalProcessprotein localization to cytoskeleton

MAP1A APC CEP63 CEP72 GOLGB1

1.57e-05631035GO:0044380
GeneOntologyBiologicalProcessprotein localization to centrosome

APC CEP63 CEP72 GOLGB1

3.80e-05381034GO:0071539
GeneOntologyBiologicalProcessprotein localization to microtubule organizing center

APC CEP63 CEP72 GOLGB1

4.22e-05391034GO:1905508
GeneOntologyBiologicalProcessmeiotic telomere clustering

SUN1 CEP63 MLH1

4.23e-05141033GO:0045141
GeneOntologyBiologicalProcesschromosome localization to nuclear envelope involved in homologous chromosome segregation

SUN1 CEP63 MLH1

4.23e-05141033GO:0090220
GeneOntologyBiologicalProcesstelomere localization

SUN1 CEP63 MLH1

5.27e-05151033GO:0034397
GeneOntologyBiologicalProcessnuclear matrix anchoring at nuclear membrane

SYNE1 SUN1

7.38e-0531032GO:0090292
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

HSPG2 FN1 MAP1A SEMA7A RPS6KA5 SYNE1 OBSL1 APC TRIOBP PAFAH1B1 LRP1 EEF2K KIF5A

8.96e-0574810313GO:0048667
GeneOntologyBiologicalProcessnuclear matrix organization

SYNE1 SUN1

1.47e-0441032GO:0043578
GeneOntologyBiologicalProcesspositive regulation of axon extension

FN1 SEMA7A PAFAH1B1 LRP1

1.64e-04551034GO:0045773
GeneOntologyBiologicalProcessregulation of protein depolymerization

MAP1A APC TRIOBP LMOD3 ASPH

1.83e-041051035GO:1901879
GeneOntologyBiologicalProcessretrograde axonal transport

MAP1A PAFAH1B1 KIF5A

2.27e-04241033GO:0008090
GeneOntologyCellularComponentmicrotubule organizing center

OBSL1 APC TRIOBP SFI1 FIGN CEP63 USP2 CEP72 PAFAH1B1 NR0B1 LRP1 TNKS MPHOSPH9 MLPH MTUS2

4.86e-0591910415GO:0005815
GeneOntologyCellularComponentcentrosome

OBSL1 APC TRIOBP FIGN CEP63 USP2 CEP72 PAFAH1B1 NR0B1 TNKS MPHOSPH9 MTUS2

4.45e-0477010412GO:0005813
GeneOntologyCellularComponentM band

OBSL1 LMOD3 KCTD6

4.86e-04311043GO:0031430
GeneOntologyCellularComponentcentral region of growth cone

PAFAH1B1 KIF5A

5.07e-0471042GO:0090724
GeneOntologyCellularComponentmicrotubule organizing center attachment site

SYNE1 SUN1

1.31e-03111042GO:0034992
GeneOntologyCellularComponentsperm head plasma membrane

ADAM21 ADAM29

1.31e-03111042GO:1990913
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

SYNE1 SUN1

1.31e-03111042GO:0034993
GeneOntologyCellularComponentnuclear membrane protein complex

SYNE1 SUN1

1.31e-03111042GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

SYNE1 SUN1

1.31e-03111042GO:0106094
MousePhenoabnormal oogenesis

SUN1 PEG3 ZFY CEP63 MLH1 EEF2K PRLR BRWD1

1.42e-05186838MP:0001931
Domain-

PEG3 ZNF865 IKZF5 ZFY RLF ZNF250 ZNF14 ZFHX4 ZNF532 ZIC5 ZNF516 ZNF700 ZNF791 ZNF583

2.13e-05679103143.30.160.60
DomainZnf_C2H2/integrase_DNA-bd

PEG3 ZNF865 IKZF5 ZFY RLF ZNF250 ZNF14 ZFHX4 ZNF532 ZIC5 ZNF516 ZNF700 ZNF791 ZNF583

2.71e-0569410314IPR013087
DomainZINC_FINGER_C2H2_2

PEG3 ZNF865 IKZF5 ZFY RLF ZNF250 ZNF14 ZFHX4 ZNF532 ZIC5 ZNF516 ZNF700 ZNF791 ZNF583

8.93e-0577510314PS50157
DomainZINC_FINGER_C2H2_1

PEG3 ZNF865 IKZF5 ZFY RLF ZNF250 ZNF14 ZFHX4 ZNF532 ZIC5 ZNF516 ZNF700 ZNF791 ZNF583

9.18e-0577710314PS00028
Domain-

DMXL2 SEMA7A EDC4 TEP1 NBAS TULP4 TECPR2 PAFAH1B1 BRWD1

9.43e-0533310392.130.10.10
DomainWD40/YVTN_repeat-like_dom

DMXL2 SEMA7A EDC4 TEP1 NBAS TULP4 TECPR2 PAFAH1B1 BRWD1

9.87e-053351039IPR015943
DomainZnf_C2H2-like

PEG3 ZNF865 IKZF5 ZFY RLF ZNF250 ZNF14 ZFHX4 ZNF532 ZIC5 ZNF516 ZNF700 ZNF791 ZNF583

1.18e-0479610314IPR015880
DomainZnf_C2H2

PEG3 ZNF865 IKZF5 ZFY RLF ZNF250 ZNF14 ZFHX4 ZNF532 ZIC5 ZNF516 ZNF700 ZNF791 ZNF583

1.33e-0480510314IPR007087
DomainZnF_C2H2

PEG3 ZNF865 IKZF5 ZFY RLF ZNF250 ZNF14 ZFHX4 ZNF532 ZIC5 ZNF516 ZNF700 ZNF791 ZNF583

1.39e-0480810314SM00355
DomainWD_REPEATS_1

DMXL2 EDC4 TEP1 NBAS TULP4 TECPR2 PAFAH1B1 BRWD1

1.53e-042781038PS00678
DomainWD_REPEATS_2

DMXL2 EDC4 TEP1 NBAS TULP4 TECPR2 PAFAH1B1 BRWD1

1.57e-042791038PS50082
DomainWD_REPEATS_REGION

DMXL2 EDC4 TEP1 NBAS TULP4 TECPR2 PAFAH1B1 BRWD1

1.57e-042791038PS50294
Domainzf-C2H2

PEG3 ZNF865 ZFY RLF ZNF250 ZNF14 ZFHX4 ZIC5 ZNF516 ZNF700 ZNF791 ZNF583

4.32e-0469310312PF00096
DomainWD40

DMXL2 EDC4 TEP1 TULP4 TECPR2 PAFAH1B1 BRWD1

7.11e-042681037SM00320
DomainWD40_repeat

DMXL2 EDC4 TEP1 TULP4 TECPR2 PAFAH1B1 BRWD1

7.76e-042721037IPR001680
DomainINT_SG_DDX_CT_C

INTS6 SAGE1

8.25e-0481032PF15300
DomainINT_SG_DDX_CT_C

INTS6 SAGE1

8.25e-0481032IPR029307
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DCHS2 DMXL2 ERBB3 FN1 SYNE1 PEG3 OBSL1 APC TRIOBP RNF40 DNAJC7 CEP63 BEX3 USP2 ZNF532 LRP1 TTC17 TNKS KIF5A ZNF583 MTUS2 ZMYM5 BRWD1

4.54e-1212851052335914814
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

SYNE1 APC RNF40 DNAJC7 CEP63 PAFAH1B1 TNKS

8.39e-08120105731413325
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

APC RNF40 RLF ZFHX4 ZNF532 ZNF516 NR0B1 LRP1 GOLGB1 ZMYM5

5.90e-074181051034709266
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

HSPG2 FN1 JADE3 SYNE1 TEP1 LRP1 MLPH

4.13e-06214105722199357
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

DMXL2 ERBB3 SAMD9 OBSL1 APC ACE2 SLC30A5 DSTYK ASPH SLTM MLH1

4.54e-066501051138777146
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AGAP5 JADE3 SUN1 TRIOBP RNF40 SFI1 HEPH ZNF532 TECPR2 ZNF516

4.83e-065291051014621295
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

SYNE1 DNAJC7 CEP63 PAFAH1B1 TNKS KIF5A

6.85e-06151105617043677
Pubmed

Mapping anti-müllerian hormone (Amh) and related sequences in the mouse: identification of a new region of homology between MMU10 and HSA19p.

FN1 ZFY MLPH

7.48e-061310531685136
Pubmed

Post-transcriptional Wnt Signaling Governs Epididymal Sperm Maturation.

APC CCNYL1

9.03e-062105226590424
Pubmed

Loss of RNF40 Decreases NF-κB Activity in Colorectal Cancer Cells and Reduces Colitis Burden in Mice.

APC RNF40

9.03e-062105230321325
Pubmed

Peroxisome proliferator-activated receptor gamma agonist troglitazone induces colon tumors in normal C57BL/6J mice and enhances colonic carcinogenesis in Apc1638 N/+ Mlh1+/- double mutant mice.

APC MLH1

9.03e-062105215818612
Pubmed

Accelerated growth of intestinal tumours after radiation exposure in Mlh1-knockout mice: evaluation of the late effect of radiation on a mouse model of HNPCC.

APC MLH1

9.03e-062105216623753
Pubmed

Differential deposition of basement membrane components during formation of the caudal neural tube in the mouse embryo.

HSPG2 FN1

9.03e-06210523665768
Pubmed

DRR drives brain cancer invasion by regulating cytoskeletal-focal adhesion dynamics.

MAP1A FAM107A

9.03e-062105220543869
Pubmed

Tumor-associated Apc mutations in Mlh1-/- Apc1638N mice reveal a mutational signature of Mlh1 deficiency.

APC MLH1

9.03e-062105211126362
Pubmed

Sulindac effects on inflammation and tumorigenesis in the intestine of mice with Apc and Mlh1 mutations.

APC MLH1

9.03e-062105219755659
Pubmed

Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance.

SERBP1 EEF2K

9.03e-062105234815424
Pubmed

Molecular interactions between perlecan LG3 and the SARS-CoV-2 spike protein receptor binding domain.

HSPG2 ACE2

9.03e-062105237996967
Pubmed

Tumor regionality in the mouse intestine reflects the mechanism of loss of Apc function.

APC MLH1

9.03e-062105215210940
Pubmed

The low density lipoprotein receptor-related protein mediates fibronectin catabolism and inhibits fibronectin accumulation on cell surfaces.

FN1 LRP1

9.03e-062105211867643
Pubmed

LRP1 is required for novobiocin-mediated fibronectin turnover.

FN1 LRP1

9.03e-062105230061663
Pubmed

Tumorigenesis in Mlh1 and Mlh1/Apc1638N mutant mice.

APC MLH1

9.03e-062105210096563
Pubmed

[Concurrent APC and MLH1mutations identified in a family affected with familial adenomatous polyposis].

APC MLH1

9.03e-062105229419868
Pubmed

Mlh1 deficiency enhances several phenotypes of Apc(Min)/+ mice.

APC MLH1

9.03e-062105210851078
Pubmed

Genetic enhancement of the Lis1+/- phenotype by a heterozygous mutation in the adenomatous polyposis coli gene.

APC PAFAH1B1

9.03e-062105218075263
Pubmed

The H2B ubiquitin ligase RNF40 cooperates with SUPT16H to induce dynamic changes in chromatin structure during DNA double-strand break repair.

RNF40 SUPT16H

9.03e-062105222031019
Pubmed

SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.

SYNE1 SUN1 PAFAH1B1

9.50e-0614105319874786
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

FN1 SEMA7A RPS6KA5 APC RNF40 ZFY INTS6 TNKS MTUS2

1.45e-05475105931040226
Pubmed

Modifier genes in mice and humans.

APC FIGN MLPH

1.46e-0516105311256068
Pubmed

CRL7SMU1 E3 ligase complex-driven H2B ubiquitylation functions in sister chromatid cohesion by regulating SMC1 expression.

OBSL1 APC RNF40

2.11e-0518105329507117
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

FN1 SUN1 PEG3 APC CEP63 NEUROD1 FAM107A CLCNKA SLTM PUM1 ARHGEF6 GOLGB1 BRWD1

2.40e-0510841051311544199
Pubmed

The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion.

SFI1 CEP63 CEP72 PAFAH1B1

2.55e-0556105411076968
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

JADE3 EDC4 RLF CEP72 ZNF516 SUPT16H SLTM MPHOSPH9 KIF5A ARHGEF6

2.67e-056451051025281560
Pubmed

Use of mononucleotide repeat markers for detection of microsatellite instability in mouse tumors.

APC MLH1

2.70e-053105216240453
Pubmed

The molecular basis of Turcot's syndrome.

APC MLH1

2.70e-05310527661930
Pubmed

The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.

SYNE1 SUN1

2.70e-053105216079285
Pubmed

Immunohistochemical localization of syndecan-1 in the dental follicle of postnatal mouse teeth.

HSPG2 FN1

2.70e-053105217608588
Pubmed

Absence of post-translational aspartyl beta-hydroxylation of epidermal growth factor domains in mice leads to developmental defects and an increased incidence of intestinal neoplasia.

APC ASPH

2.70e-053105211773073
Pubmed

Angioinhibitory action of NK4 involves impaired extracellular assembly of fibronectin mediated by perlecan-NK4 association.

HSPG2 FN1

2.70e-053105219553700
Pubmed

EBV-infection in cardiac and non-cardiac gastric adenocarcinomas is associated with promoter methylation of p16, p14 and APC, but not hMLH1.

APC MLH1

2.70e-053105221538028
Pubmed

Mouse models of gastrointestinal tumors.

APC PTGS1

2.70e-053105216630131
Pubmed

Genetic disruption of Ptgs-1, as well as Ptgs-2, reduces intestinal tumorigenesis in Min mice.

APC PTGS1

2.70e-053105210987272
Pubmed

BET protein-dependent E2F pathway activity confers bell-shaped type resistance to tankyrase inhibitors in APC-mutated colorectal cancer.

APC TNKS

2.70e-053105238216082
Pubmed

Inhibitory effects of mofezolac, a cyclooxygenase-1 selective inhibitor, on intestinal carcinogenesis.

APC PTGS1

2.70e-053105212189188
Pubmed

EBV-infection in cardiac and non-cardiac gastric adenocarcinomas is associated with promoter methylation of p16, p14 and APC, but not hMLH1.

APC MLH1

2.70e-053105220978327
Pubmed

Epithelial-specific ERBB3 deletion results in a genetic background-dependent increase in intestinal and colon polyps that is mediated by EGFR.

ERBB3 APC

2.70e-053105234843459
Pubmed

Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium.

ERBB3 APC

2.70e-053105219690388
Pubmed

Cooperation of cyclooxygenase 1 and cyclooxygenase 2 in intestinal polyposis.

APC PTGS1

2.70e-053105212941808
Pubmed

Colorectal cancer prevention.

APC MLH1

2.70e-053105215375803
Pubmed

The cyclooxygenase-2-mediated prostaglandin signaling is causally related to epithelial carcinogenesis.

APC PTGS1

2.70e-053105217546626
Pubmed

The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation.

SFI1 CEP63 CEP72 PAFAH1B1

2.74e-0557105416462731
Pubmed

Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation.

SFI1 CEP63 CEP72 PAFAH1B1

2.94e-0558105412852856
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

DMXL2 SYNE1 APC TRIOBP EDC4 ZNF516 SUPT16H NT5C2 LRP1 TNKS KIF5A GOLGB1

3.49e-059631051228671696
Pubmed

Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function.

SFI1 CEP63 CEP72 PAFAH1B1

3.59e-056110547790358
Pubmed

DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation.

MAP1A SYNE1 CEP63

3.95e-0522105312812986
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

SGSM1 TRIOBP TEP1 RLF ANKRD44 INTS6 TULP4 ZNF532 TECPR2 ASPH NT5C2 LRP1 TTC17 MLPH GOLGB1

4.13e-0514891051528611215
Pubmed

Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex.

SFI1 CEP63 CEP72 PAFAH1B1

4.89e-0566105412221128
Pubmed

Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K.

APC EEF2K

5.40e-054105234895463
Pubmed

Mouse models expressing human carcinoembryonic antigen (CEA) as a transgene: evaluation of CEA-based cancer vaccines.

APC MLH1

5.40e-054105215888344
Pubmed

SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.

SYNE1 SUN1

5.40e-054105216648470
Pubmed

Pancreatic Cancer with Mutation in BRCA1/2, MLH1, and APC Genes: Phenotype Correlation and Detection of a Novel Germline BRCA2 Mutation.

APC MLH1

5.40e-054105235205366
Pubmed

Tankyrases maintain homeostasis of intestinal epithelium by preventing cell death.

APC TNKS

5.40e-054105230260955
Pubmed

Limiting oxidative DNA damage reduces microbe-induced colitis-associated colorectal cancer.

APC MLH1

5.40e-054105232286276
Pubmed

Hypermethylation of hMLH1, HPP1, p14(ARF), p16(INK4A) and APC in primary adenocarcinomas of the small bowel.

APC MLH1

5.40e-054105216619216
Pubmed

Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture.

SYNE1 SUN1

5.40e-054105228716842
Pubmed

A reciprocal relationship exists between non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) and cyclooxygenase-2.

APC PTGS1

5.40e-054105219375854
Pubmed

Mammalian sperm head formation involves different polarization of two novel LINC complexes.

SYNE1 SUN1

5.40e-054105220711465
Pubmed

Prelamin A causes aberrant myonuclear arrangement and results in muscle fiber weakness.

SYNE1 SUN1

5.40e-054105230282816
Pubmed

LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina.

SYNE1 SUN1

5.40e-054105223071752
Pubmed

Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.

SYNE1 SUN1

5.40e-054105220108321
Pubmed

Nesprin-1α-Dependent Microtubule Nucleation from the Nuclear Envelope via Akap450 Is Necessary for Nuclear Positioning in Muscle Cells.

SYNE1 SUN1

5.40e-054105228966089
Pubmed

Common variants in human CRC genes as low-risk alleles.

APC MLH1

5.40e-054105220149637
Pubmed

Missense mutations in MLH1, MSH2, KRAS, and APC genes in colorectal cancer patients in Malaysia.

APC MLH1

5.40e-054105222669205
Pubmed

Expression and promoter methylation status of hMLH1, MGMT, APC, and CDH1 genes in patients with colon adenocarcinoma.

APC MLH1

5.40e-054105225908636
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

DMXL2 SYNE1 OBSL1 TRIOBP HEPH CEP72

6.47e-05225105612168954
Pubmed

CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination.

SUN1 CEP63 MLH1

7.42e-0527105326158450
Pubmed

Epilepsy- and intellectual disability-associated CYFIP2 interacts with both actin regulators and RNA-binding proteins in the neonatal mouse forebrain.

SEMA7A SUN1 TRIOBP DNAJC7 PUM1

7.60e-05143105532560809
Pubmed

Functional proteomics mapping of a human signaling pathway.

HSPG2 FN1 DNAJC7 PRPF40A RLF LRP1 PUM1 GOLGB1 ZMYM5

7.86e-05591105915231748
Pubmed

Cholesteryl ester transfer protein (CETP) expression enhances HDL cholesteryl ester liver delivery, which is independent of scavenger receptor BI, LDL receptor related protein and possibly LDL receptor.

PDZK1 LRP1

8.97e-055105217055779
Pubmed

Promoter methylation profile in gallbladder cancer.

APC MLH1

8.97e-055105216699861
Pubmed

Semaphorin 7A promotes axon outgrowth through integrins and MAPKs.

FN1 SEMA7A

8.97e-055105212879062
Pubmed

MGMT and MLH1 promoter methylation versus APC, KRAS and BRAF gene mutations in colorectal cancer: indications for distinct pathways and sequence of events.

APC MLH1

8.97e-055105219164452
Pubmed

A molecular mechanism for LINC complex branching by structurally diverse SUN-KASH 6:6 assemblies.

SYNE1 SUN1

8.97e-055105233393904
Pubmed

LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins.

SYNE1 SUN1

8.97e-055105222632968
Pubmed

Mutations in APC, CTNNB1 and K-ras genes and expression of hMLH1 in sporadic colorectal carcinomas from the Netherlands Cohort Study.

APC MLH1

8.97e-055105216356174
Pubmed

LEF1 and B9L shield β-catenin from inactivation by Axin, desensitizing colorectal cancer cells to tankyrase inhibitors.

APC TNKS

8.97e-055105224419084
Pubmed

Spatial and temporal changes in chondroitin sulfate distribution in the sclerotome play an essential role in the formation of migration patterns of mouse neural crest cells.

HSPG2 FN1

8.97e-05510529915576
Pubmed

Heparan sulphate proteoglycan and the low-density lipoprotein receptor-related protein 1 constitute major pathways for neuronal amyloid-beta uptake.

HSPG2 LRP1

8.97e-055105221289173
Pubmed

Disruption of the talin gene arrests mouse development at the gastrulation stage.

HSPG2 FN1

8.97e-055105211084655
Pubmed

Introduction of cytogenetic tests in colorectal cancer screening.

APC MLH1

8.97e-055105219337631
Pubmed

Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.

SYNE1 SUN1

8.97e-055105218396275
Pubmed

Mapping of binding sites for nidogens, fibulin-2, fibronectin and heparin to different IG modules of perlecan.

HSPG2 FN1

8.97e-055105211493006
Pubmed

Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas.

APC MLH1

8.97e-055105215520370
Pubmed

An inter-species protein-protein interaction network across vast evolutionary distance.

RNF40 TUFT1 CEP63 ZNF250 CEP72 NT5C2 MLH1 MTUS2

1.12e-04483105827107014
Pubmed

A human MAP kinase interactome.

MAP1A RPS6KA5 SYNE1 APC DNAJC7 MPHOSPH9 KIF5A GOLGB1

1.17e-04486105820936779
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

HSPG2 ERBB3 SERBP1 FN1 SEMA7A MCFD2 RNF40 PRPF40A PTGS1 SLC30A5 ASPH SUPT16H NT5C2 LRP1

1.20e-0414511051430550785
Pubmed

The utility and predictive value of combinations of low penetrance genes for screening and risk prediction of colorectal cancer.

APC PTGS1 MLH1

1.24e-0432105320437058
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

HSPG2 SEMA7A RNF40 SFI1 EDC4 TEP1 ZNF865 MROH6 TULP4 ZNF516 TTC5 PUM1

1.29e-0411051051235748872
Pubmed

Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis.

TRIOBP PAFAH1B1

1.34e-046105231815665
Pubmed

The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin.

HSPG2 FN1

1.34e-046105211956183
InteractionNDEL1 interactions

SYNE1 OBSL1 APC TRIOBP CEP63 ZNF250 USP2 PAFAH1B1 KIF5A MTUS2

1.31e-0816410410int:NDEL1
InteractionPCNT interactions

DMXL2 SYNE1 TPTE2 OBSL1 DNAJC7 CEP63 CEP72 PAFAH1B1 MPHOSPH9

4.41e-062411049int:PCNT
InteractionKIAA0753 interactions

TPTE2 DNAJC7 IKZF5 CEP63 CEP72 MPHOSPH9 PUM1

1.72e-051571047int:KIAA0753
InteractionMYOM1 interactions

SGCA SYNE1 LMOD3 MTUS2

1.89e-05311044int:MYOM1
InteractionPDIA4 interactions

ERBB3 SERBP1 SYNE1 SUN1 OBSL1 RNF40 ACE2 PAFAH1B1 ASPH TTC17 ARHGEF6

3.01e-0546810411int:PDIA4
InteractionTUBB4B interactions

SERBP1 FN1 OBSL1 APC DNAJC7 ACE2 DSTYK PAFAH1B1 NT5C2 LRP1 MPHOSPH9 TTC5

3.19e-0556010412int:TUBB4B
InteractionWHAMMP3 interactions

DMXL2 SYNE1 TRIOBP RNF40 CEP63 KIF5A

3.54e-051191046int:WHAMMP3
InteractionMTDH interactions

HSPG2 SERBP1 FN1 JADE3 SYNE1 TEP1 ACE2 SUPT16H LRP1 MLPH MTUS2

5.99e-0550510411int:MTDH
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

PEG3 ZNF865 IKZF5 ZFY RLF ZNF250 ZNF14 ZNF532 ZIC5 ZNF516 ZNF700 ZNF791 ZNF583

3.80e-06718711328
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

DMXL2 SEMA7A SUN1 SFI1 ANKRD44 NBAS TTC17

2.69e-071851047a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

DMXL2 SEMA7A SUN1 SFI1 ANKRD44 NBAS TTC17

2.79e-0718610478571956890fc9894d766ba294a28e376b4aba428
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DCHS2 SYNE1 APC HEPH ZFHX4 FAM107A ASPH

4.56e-07200104707d942803360e1a1e8e131d6e31c726dd0db1a0b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DCHS2 SYNE1 APC HEPH ZFHX4 FAM107A ASPH

4.56e-072001047d0812817ef99608994193787a62d39adeb2070ca
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DCHS2 SYNE1 APC HEPH ZFHX4 FAM107A ASPH

4.56e-072001047cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCellfacs-Pancreas-Endocrine-3m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JADE3 PEG3 ACE2 BEX3 NEUROD1 TULP4

5.81e-061911046b3de0393d6510543533cd851e47a0f95739a0e4e
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RPS6KA5 SYNE1 SFI1 ANKRD44 ZNF14 BRWD1

6.17e-0619310469337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FN1 SGCA PEG3 FIGN ZFHX4 LRP1

6.54e-061951046ec12cfb2fce44cc2de4e198ef5af075e626f0329
ToppCellFibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

HSPG2 FN1 MAP1A BEX3 ZFHX4 LRP1

7.35e-06199104640de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCellThalamus|World / BrainAtlas - Mouse McCarroll V32

FIGN CACNA2D4 ZFHX4 ZIC5 TRIM40

7.84e-0611610455ddfb2dd5459ff6d7ae38163a38eae64fda283b7
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SGSM1 RPS6KA5 ANKRD44 LMOD3 GABPB2

1.64e-0513510459f9d0787a2e99207a9caa88a85565189ab8b940a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SGSM1 RPS6KA5 ANKRD44 LMOD3 GABPB2

2.80e-0515110452f9b3e14c2fa6e2b1976ca6ab2031b63bf5e3e64
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RPS6KA5 PTGS1 ANKRD44 MLPH ARHGEF6

4.16e-0516410452c48c6e4eeee845f0563982d0bfa2a176ca5ef61
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS6KA5 TEP1 TUFT1 RLF ZFHX4

4.54e-051671045f5bffa77061baec0ba87bd688a047595f32534db
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 DCHS2 FIGN LRP1 PRLR

4.94e-0517010455570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellNS-moderate-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CLCNKA NR0B1 OTUD7A MTUS2 PRLR

5.66e-051751045a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCellCOVID-19-lung-MAST|COVID-19 / Disease (COVID-19 only), tissue and cell type

RPS6KA5 PTGS1 ANKRD44 MLPH ARHGEF6

5.82e-051761045473c45a381ca109207d66ed1635668b391ea0e1f
ToppCellmetastatic_Brain-Endothelial_cells-Lymphatic_ECs|Endothelial_cells / Location, Cell class and cell subclass

MAP1A SGCA LMOD3 ZFHX4 LRP1

5.82e-05176104542541dfe20eb29625d47c0bb79bf3c21a2460340
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6|TCGA-Ovary / Sample_Type by Project: Shred V9

FN1 SEMA7A SYNE1 HEPH LRP1

6.14e-051781045142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FN1 SYNE1 ANKRD44 ZFHX4 MTUS2

6.14e-0517810450fb36679cddc9ed8f4b5b34e174d5133c2ea1c76
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ERBB3 ABCA13 SUN1 TUFT1 GOLGB1

6.30e-0517910456e965e424eebef50f0202cff75f458be395cfca1
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 ERBB3 MAP1A FIGN ZFHX4

6.82e-051821045a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCellfacs-Skin-Telogen-3m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM45A PTGS1 ACE2 EEF2K CARD14

7.00e-051831045ed1e0b07475f9951728682ed70b85367cf2a744d
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 SFI1 FIGN ZFHX4 KIF5A

7.18e-0518410452cbed6462fea2622871bb7e49b0df3d984239281
ToppCellTransplant_Alveoli_and_parenchyma-Immune-Mast_cells|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

MAP1A SEMA7A RPS6KA5 PTGS1 MLPH

7.18e-051841045bc394eaa441fcaffcc4ace062741bca1da229324
ToppCellIPF-Myeloid-Mast|World / Disease state, Lineage and Cell class

SEMA7A RPS6KA5 PTGS1 NBAS ARHGEF6

7.18e-0518410457aefa182acad5a53c730945fec85329d7168606a
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 SFI1 FIGN ZFHX4 KIF5A

7.18e-051841045ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 SFI1 FIGN ZFHX4 KIF5A

7.18e-0518410452b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellIPF-Myeloid-Mast|IPF / Disease state, Lineage and Cell class

SEMA7A RPS6KA5 PTGS1 NBAS ARHGEF6

7.18e-051841045c3baf21f10b45cf91ac99997a59f353bcf3de8b7
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 RFTN2 FIGN LRP1 EEF2K

7.75e-051871045d591a3c216997663ab77710fed0d230ffc37e41a
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RFTN2 HEPH ZFHX4 FAM107A ZIC5

7.75e-0518710455d3d68519c8e19f10c29f9d81712125be78ca15a
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 RFTN2 FIGN LRP1 EEF2K

7.75e-051871045d1dc8c9a2c2cd10c640257161a75e7730ec5bb41
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 RFTN2 FIGN LRP1 EEF2K

7.75e-051871045ac8e092b37e042975e2ee057d3f7c6821e58e8b5
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RFTN2 HEPH ZFHX4 FAM107A ZIC5

7.75e-0518710455c73010fe4c85fb5cc1273f5504821229ca0cc4b
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RFTN2 HEPH ZFHX4 FAM107A ZIC5

7.75e-05187104593c78fc7f126132eb84feb47be2c4e8c568b9e91
ToppCellEndothelial-Endothelial-E|Endothelial / shred on cell class and cell subclass (v4)

HSPG2 FN1 TMEM45A PTGS1 EEF2K

7.95e-0518810452777eb7689b271c199021fe7d9db88ccebff14de
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FN1 BEX3 ADPRH LRP1 TTC5

7.95e-051881045e35104ca327c2d9eb6ffed658051f62f855a0a0e
ToppCell10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

HSPG2 FN1 SGCA FIGN ZFHX4

7.95e-051881045de6f4889e0c5f39fbbaefd85526f645c6afa09d5
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG3 NEUROD1 ZNF516 PRLR GOLGB1

7.95e-051881045a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RFTN2 HEPH ZFHX4 FAM107A ZIC5

8.35e-0519010455c64b727669b23d2a23c8ad1d5d6caab7af37d56
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RFTN2 HEPH ZFHX4 FAM107A ZIC5

8.35e-0519010453a55cc5dc2549788bfe55f649686887b21a1fdd2
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RFTN2 HEPH ZFHX4 FAM107A ZIC5

8.35e-0519010451c3d601422efa60fad8565f9ccd9032b847e4a91
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG3 BEX3 NEUROD1 PRLR GOLGB1

8.56e-051911045fd01a206763dfb6d52cca67123571936b4a8e1a0
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

SUN1 SFI1 ANKRD44 NBAS TTC17

8.56e-0519110459454f642c3621370fa23640b631301346b300950
ToppCell390C-Myeloid-Mast_cell-|390C / Donor, Lineage, Cell class and subclass (all cells)

SEMA7A RPS6KA5 PTGS1 MLPH ARHGEF6

8.56e-05191104588bcd0b85b2112cef15c9e44d1429f9fba4a3400
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG3 ACE2 BEX3 NEUROD1 TULP4

8.56e-051911045657297cd19d05a7e7bb74fc3a086fbd95f47aae4
ToppCell390C-Myeloid-Mast_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

SEMA7A RPS6KA5 PTGS1 MLPH ARHGEF6

8.56e-051911045c1517ea7b10a7f732725b4c0224fbfecae80d18b
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RFTN2 HEPH ZFHX4 FAM107A ZIC5

8.77e-051921045f7e4509003d71f805b9d4587098e90d2897b6739
ToppCelldroplet-Pancreas-Endocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG3 BEX3 NEUROD1 PRLR GOLGB1

8.77e-0519210450dfd1e9896c34aee0f842f8de5d0e3af62a15f68
ToppCelldroplet-Pancreas-Endocrine-18m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG3 BEX3 NEUROD1 PRLR GOLGB1

8.77e-0519210454510aa262da8dcf7c944b3907a51aba5a9397a4e
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RFTN2 HEPH ZFHX4 FAM107A ZIC5

8.77e-051921045705ce805cb00a53793b57bcf466d0fbec590a83c
ToppCellsevere_COVID-19|World / disease group, cell group and cell class (v2)

MAP1A TMEM45A PTGS1 BEX3 ASPH

8.99e-0519310459012cadd138be775fb167a5bc895e512619f8a95
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG3 NEUROD1 ZNF516 PRLR GOLGB1

8.99e-051931045471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG3 NEUROD1 ZNF516 PRLR GOLGB1

8.99e-051931045fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCelldroplet-Pancreas-Endocrine-21m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG3 NEUROD1 ZNF516 PRLR GOLGB1

9.21e-0519410453a3ecedcdc7691cf21775818b598208fcb980c29
ToppCellmedial-2-Hematologic-Basophil/Mast_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SEMA7A RPS6KA5 PTGS1 MLPH ARHGEF6

9.21e-05194104554d33508ce35b3d214214e4efbbb62f358667105
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG3 BEX3 NEUROD1 PRLR GOLGB1

9.21e-05194104592b39a935e8c577eb1123d706d168fa13cf3344c
ToppCellmedial-Hematologic-Basophil/Mast_1-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SEMA7A RPS6KA5 PTGS1 MLPH ARHGEF6

9.21e-051941045a89a03d4adebb9f644c27e199bff267180d8ef18
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG3 NEUROD1 ZNF516 PRLR GOLGB1

9.21e-0519410450b023de48ed8a550d169bbe954881eb04bf4f981
ToppCellmedial-Hematologic-Basophil/Mast_1|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SEMA7A RPS6KA5 PTGS1 MLPH ARHGEF6

9.21e-051941045ccfc142fe10b4ba16f3036f3f352983ee3e9c8ec
ToppCelldistal-Hematologic-Basophil/Mast_1-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MAP1A SEMA7A PTGS1 MLPH ARHGEF6

9.44e-0519510454f83449fce3717518e2acbba1a4b3bea765c0bdb
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG3 NEUROD1 TULP4 ZNF516 GOLGB1

9.44e-0519510457796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FN1 TMEM45A SYNE1 PEG3 BEX3

9.90e-0519710459af431323da6d099459b7360af40e5df998cffbd
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 INTS6 ASPH MLPH PRLR

9.90e-051971045bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FN1 TMEM45A SYNE1 PEG3 BEX3

1.01e-041981045a883e25cb7a78b2ecfb15cef4633bdd02dfafb12
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DCHS2 PEG3 BEX3 ZFHX4 MTUS2

1.01e-04198104512cd9f0bbad8dce5199ebfed1c4a8080710ca055
ToppCellfacs-Trachea-nan-3m-Mesenchymal-chondrocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 TMEM45A PEG3 RFTN2 FAM107A

1.01e-04198104571e847e8c24744d6df4a960348ad2ecf310373b4
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon-Radial_glial-oRG/Astroglia|6_mon / Sample Type, Dataset, Time_group, and Cell type.

OBSL1 APC ZFHX4 FAM107A ASPH

1.04e-0419910450b96fad1be02f0fe7a608207770cc56a6b6b291e
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid-Megakaryocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA7A RPS6KA5 SFI1 KCTD6 CCNYL1

1.06e-0420010450d76b006d8e8b32174e65e400acd0674354b962c
ToppCellSkin-Keratinocytes|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

ERBB3 SERBP1 TMEM45A PTGS1 TUFT1

1.06e-04200104559d72395199bc30df0e811fbc99149694e208860
ToppCellBronchial-10x5prime-Immune_Myeloid-Mast_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA7A RPS6KA5 PTGS1 MLPH ARHGEF6

1.06e-04200104596540be0e906bbc626049a41978be3dc051d2024
ToppCellBronchial-10x5prime-Immune_Myeloid-Mast_cell-Mast_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA7A RPS6KA5 PTGS1 MLPH ARHGEF6

1.06e-04200104541d7736427494cb30a2f23722ea2b86ff308cfd8
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA7A RPS6KA5 SFI1 KCTD6 CCNYL1

1.06e-042001045cc8368665bc6bb7c4f39632ccff07ceaa98a7b65
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_adventitial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FN1 MAP1A TMEM45A PTGS1 LRP1

1.06e-04200104574ad0ae592252060ee294d7483327d765a6ba1dd
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MAP1A TMEM45A SGCA ADAM21 PTGS1

1.06e-0420010453e0041c04e42a47257517dae8707a6454570c256
ToppCellParenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HSPG2 TMEM45A RFTN2 CACNA2D4 TTC5

1.06e-0420010458a4c210a3130f7baedf15ecbc0f4903b97da0352
ToppCellTracheal-10x5prime-Stromal-Fibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FN1 MAP1A TMEM45A PTGS1 LRP1

1.06e-0420010457ba292c30d915e66ebc8026fa76492cedf64700e
ToppCellASK428-Endothelial-Endothelium|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq

HSPG2 FAM107A TTC17

1.20e-04411043a72d926de3dc9e420b80764af88002e436517790
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf|Hippocampus / BrainAtlas - Mouse McCarroll V32

ERBB3 CACNA2D4 CCNYL1 CEP72

1.74e-0411910447367b6e4906d234ca864075443efe420ee407421
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Trf.Ctps_(Ctps)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ERBB3 CACNA2D4 CCNYL1 CEP72

1.74e-0411910440c9aff5442a1b1e51e142d6527d5a48211d94335
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P1-P1_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

ERBB3 CACNA2D4 CCNYL1 CEP72

1.74e-0411910440dd72dbded7ade911612d20e0c6e3f40e85fc890
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SGSM1 RPS6KA5 LMOD3 GABPB2

2.24e-041271044fbf7e6bea9991628e98f75c279e2992031dcb8db
DrugAustricine [10180-88-8]; Down 200; 14.2uM; MCF7; HT_HG-U133A

SAMD9 TMEM45A APC SFI1 SLC30A5 DSTYK PAFAH1B1 PRLR

3.86e-0620010484797_DN
DrugMagnetite Nanoparticles

SERBP1 FN1 SEMA7A RPS6KA5 RFTN2 SFI1 PRPF40A PTGS1 IKZF5 ANKRD44 USP2 ZFHX4 PAFAH1B1 ASPH SLTM NT5C2 LRP1 ARHGEF6 BRWD1

6.74e-06131010419ctd:D058185
Drugcamphene

TRIOBP IKZF5 SAGE1

1.49e-05111043CID000006616
DrugSuccimer

SERBP1 FN1 SEMA7A RPS6KA5 RFTN2 SFI1 PRPF40A PTGS1 IKZF5 ANKRD44 USP2 ZFHX4 PAFAH1B1 ASPH SLTM LRP1 ARHGEF6 BRWD1

1.56e-05126410418ctd:D004113
DrugLY 294002; Up 200; 10uM; PC3; HT_HG-U133A

RPS6KA5 SFI1 ZNF516 ASPH LRP1 PUM1 PRLR

2.36e-0518610474463_UP
DrugGanciclovir [82410-32-0]; Down 200; 15.6uM; MCF7; HT_HG-U133A

SUN1 APC TEP1 ZFHX4 DSTYK ASPH PRLR

2.45e-0518710473368_DN
Drugestradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A

SAMD9 APC SFI1 PTGS1 USP2 NEUROD1 ASPH

2.90e-0519210475238_UP
Drug(+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Down 200; 11uM; MCF7; HT_HG-U133A

HSPG2 TMEM45A APC SFI1 SLC30A5 ZFHX4 ASPH

3.10e-0519410473384_DN
DrugHymecromone [90-33-5]; Down 200; 22.8uM; MCF7; HT_HG-U133A

DMXL2 SEMA7A SFI1 TEP1 ZNF250 USP2 SLC30A5

3.30e-0519610473383_DN
DrugIsoxsuprine hydrochloride [579-56-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A

FN1 APC ZNF250 SLC30A5 ZNF516 PRLR ZMYM5

3.41e-0519710471485_UP
DrugFludrocortisone acetate [514-36-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A

HSPG2 ERBB3 SUN1 OBSL1 APC SFI1 CARD14

3.41e-0519710472328_UP
DiseaseMalignant Central Nervous System Neoplasm

APC MLH1

1.11e-052992C0348374
Diseasecortical surface area measurement

DCHS2 ERBB3 SAMD9 SGCA CALHM1 APC TRIOBP RFTN2 DSTYK PAFAH1B1 NT5C2 MLH1 TNKS MPHOSPH9 PRLR

4.15e-0513459915EFO_0010736
DiseaseCentral Nervous System Neoplasms

APC MLH1

6.66e-054992C0085136
DiseaseIntestinal Polyps

APC PTGS1

1.11e-045992C0021846
DiseaseTurcot syndrome (disorder)

APC MLH1

1.11e-045992C0265325
DiseaseLynch Syndrome

APC MLH1

3.95e-049992C4552100
Diseaserenovascular hypertension (implicated_via_orthology)

FN1 PTGS1

3.95e-049992DOID:1591 (implicated_via_orthology)
DiseaseOligospermia

NR0B1 BRWD1

7.20e-0412992C0028960
DiseaseIntellectual Disability

SYNE1 APC ACE2 SUPT16H NT5C2 KIF5A PUM1

7.85e-04447997C3714756
DiseaseDEAFNESS, AUTOSOMAL RECESSIVE (disorder)

DMXL2 TRIOBP

8.48e-0413992C1846647
DiseaseSpastic Paraplegia, Hereditary

TECPR2 KIF5A

9.88e-0414992C0037773
Diseaseresponse to triptolide, cytotoxicity measurement

ZNF532 MTUS2

1.30e-0316992EFO_0006952, EFO_0007662
DiseaseBenign neoplasm of stomach

ERBB3 APC

1.47e-0317992C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

ERBB3 APC

1.47e-0317992C0496905
Diseasemuscular dystrophy (is_implicated_in)

SGCA SYNE1

1.47e-0317992DOID:9884 (is_implicated_in)
DiseaseCarcinoma in situ of stomach

ERBB3 APC

1.47e-0317992C0154060
Diseasedehydroepiandrosterone sulphate measurement

SERBP1 ABCA13 PRLR

1.57e-0368993EFO_0007001
Diseaselaryngeal squamous cell carcinoma (is_marker_for)

ERBB3 MLH1

1.84e-0319992DOID:2876 (is_marker_for)
Diseaseglaucoma (is_marker_for)

PTGS1 HEPH

2.04e-0320992DOID:1686 (is_marker_for)
Diseaseunipolar depression, bipolar disorder, schizophrenia, sex interaction measurement

DNAJC7 NBAS SLTM

2.16e-0376993EFO_0003761, EFO_0008343, MONDO_0004985, MONDO_0005090
DiseaseStomach Carcinoma

ERBB3 APC

2.24e-0321992C0699791
DiseaseDisease Exacerbation

ERBB3 SERBP1 ABCA13 NBAS

2.35e-03165994C0235874
Diseasecholangiocarcinoma (is_implicated_in)

APC ASPH

2.46e-0322992DOID:4947 (is_implicated_in)
DiseaseNasopharyngeal carcinoma

ERBB3 SYNE1

2.46e-0322992C2931822
DiseaseColorectal Carcinoma

FN1 ABCA13 SYNE1 PEG3 APC ADAM29 LRP1 MLH1

2.53e-03702998C0009402
Diseaseblood phosphate measurement

HSPG2 SEMA7A RPS6KA5 GOLGB1

2.85e-03174994EFO_0010972

Protein segments in the cluster

PeptideGeneStartEntry
AHHLGHNLGMNHDED

ADAM29

331

Q9UKF5
VTDHMLAIGSLDHAH

ERBB3

756

P21860
NSHLRHIEHMESDEL

RNF40

421

O75150
ERHMEDTHPDHQDIL

ARHGEF6

391

Q15052
HESTVEHTHVDINEM

NT5C2

486

P49902
RILMGELSNHHDHHD

BEX3

91

Q00994
HELGHTLGMQHDEEF

ADAM21

341

Q9UKJ8
PRLHTSHDHVEDGMD

ABCA13

186

Q86UQ4
FEAMNHDLELGHTHG

CALHM1

251

Q8IU99
HEMVHAEHVEGEDLQ

ASPH

156

Q12797
AREMSEVTAELHHTH

CEP72

496

Q9P209
PDQTAMHEVQRHISH

DMXL2

336

Q8TDJ6
FGQEHARVLSSHLMH

DMXL2

1506

Q8TDJ6
HHLQHISDREMPEDL

CCNYL1

61

Q8N7R7
DDHDHKVQELMSTHE

MTUS2

1161

Q5JR59
THGSHLRLHQMSVAD

HSPG2

2676

P98160
HDGDIESMLHVRHGS

RFTN2

176

Q52LD8
HLDHSDPITRDHMGS

EDC4

1346

Q6P2E9
SRSHQELHRELLMNH

FAM107A

41

O95990
ERPTNHMEALGHDHL

INTS6

746

Q9UL03
HMEALGHDHLGTNDL

INTS6

751

Q9UL03
RTMHGHDHNVSSVAI

PAFAH1B1

186

P43034
ESNHDSHMAKERAHS

PDZK1

491

Q5T2W1
PHDSRLSMAQDGHIH

OBSL1

1491

O75147
EEAHAEDSVMDHHFR

SERBP1

331

Q8NC51
VMSEHGDEHRQLLSH

FIGN

426

Q5HY92
EMGHLMQAEDTSHHT

MAP1A

1236

P78559
LDKNTVHDQEHIMEH

MCFD2

41

Q8NI22
VHDQEHIMEHLEGVI

MCFD2

46

Q8NI22
HNQRHMLGHHAEMEI

LMOD3

346

Q0VAK6
SGHMEVLRGHEFLSH

LRP1

1466

Q07954
EHENMLSLRHNSRIH

MPHOSPH9

646

Q99550
AVSHMHDVGVVHRDL

RPS6KA5

531

O75582
LASAMVAHADHHLRG

MROH6

346

A6NGR9
RTALHHAALNGHVEM

ANKRD44

141

Q8N8A2
LLTSHRHQFHEEMIG

OTUD7A

641

Q8TE49
GRNMDHHILHVAVDV

PTGS1

436

P23219
YERHLEAHMRSHTGE

IKZF5

121

Q9H5V7
MELLESSHHEAEFQH

NBAS

2161

A2RRP1
AAHVLAELEVTMHHA

DSTYK

201

Q6XUX3
HSSALNEHMRLHRED

PEG3

1236

Q9GZU2
IHAEHQVRSMDELNH

PUM1

116

Q14671
ALDREHRGHHEMTVL

DCHS2

1251

Q6V1P9
HRGHHEMTVLVTDRG

DCHS2

1256

Q6V1P9
IFLDELHEHGQLHSM

PRPF40A

616

O75400
LSEHTRMTHQGPHDR

NR0B1

411

P51843
DHSRMKREVSAHFHE

CARD14

176

Q9BXL6
NVNDTFHKRHEEGHM

FN1

526

P02751
HVLSRPMVINHDHDI

CACNA2D4

471

Q7Z3S7
THKEVGMLHQQVEEH

CEP63

71

Q96MT8
MDDFLTAHHEMGHIQ

ACE2

366

Q9BYF1
EDMLNSEHKHRHTNI

BRWD1

2021

Q9NSI6
LMHHPDRHSGASAEV

DNAJC7

406

Q99615
HHMSERANENTVEHN

KCTD6

211

Q8NC69
LQMESHREAHHRQLA

KIF5A

701

Q12840
MASRDHDHLDNHRES

EEF2K

421

O00418
ERHCHENMNHAIETE

JADE3

176

Q92613
EESIRAHVMASHHSK

MLPH

316

Q9BV36
DRTPLHMAAADGHAH

GABPB2

71

Q8TAK5
HMAAADGHAHIVELL

GABPB2

76

Q8TAK5
AQFEMAEEHHRHSQL

SFI1

371

A8K8P3
SPEHMSHHELTIENA

TRIM40

96

Q6P9F5
IMDHQVALTRHKDHA

SYNE1

1796

Q8NF91
PDHHEELHAEQMRCK

SYNE1

7701

Q8NF91
MHTLLLTRHRDEHEG

SAMD9

1031

Q5K651
LAMGQDVDLHTIHFH

HEPH

991

Q9BQS7
ADHTAHEEMEAHTTV

SLTM

221

Q9NWH9
QGHEVLREMLHNHSF

MLH1

516

P40692
EITTDLGKHQHMHDR

SUPT16H

746

Q9Y5B9
MVHHCTIHGNTEELR

SGCA

331

Q16586
SHQQVMEELQRHHER

TRIOBP

2121

Q9H2D6
VEVGEDLHMHHIRDQ

AGAP5

56

A6NIR3
LIQVSIESGRMTHHH

ADPRH

151

P54922
HKIHSANHMDDNDGE

APC

1006

P25054
HHHFGREAEMRELIQ

CLEC4F

91

Q8N1N0
GSHHVRVEHFMNHSI

CLCNKA

541

P51800
IFQRHAHEQDTKMHE

UHRF1BP1L

656

A0JNW5
HDRMEHLIEKQISHG

TUFT1

341

Q9NNX1
CHGRMLAHVLLHESD

TULP4

196

Q9NRJ4
GHLRAHMRAHSVVFE

ZNF516

1111

Q92618
ESGHDDHESHMKQNA

ZNF532

31

Q9HCE3
DHESHMKQNAHGEDD

ZNF532

36

Q9HCE3
ASHLRMHERTHTGEK

ZNF700

576

Q9H0M5
HAVHDHRMTLNDEEQ

ZFHX4

296

Q86UP3
RMFSEREHSLHHSHE

TMEM196

141

Q5HYL7
REHSLHHSHEMAEKE

TMEM196

146

Q5HYL7
SSHLVQHMLVHSGER

ZNF865

236

P0CJ78
HTSVLTHMITHNGDR

ZNF791

256

Q3KP31
HRSTLMNHERIHTEE

ZNF250

406

P15622
EHGASHLLEHVGQMD

TEP1

846

Q99973
HHLMEQHNIEGEIHS

RLF

1426

Q13129
TVNHHVHEARMENGQ

SAGE1

436

Q9NXZ1
MPAFLHEEEQHHLER

TRIM51

186

Q9BSJ1
AERAHNDVMEVLHKH

TNKS

566

O95271
EDQHLMSVHSKEHPS

PRLR

321

P16471
VGMSHDRHVAATAHN

TMED6

76

Q8WW62
EHSHHVMDSVRQAKL

TTC5

156

Q8N0Z6
VAVHRMQASHGETFH

SEMA7A

411

O75326
AEEDDIRTEMPHCHH

TECPR2

561

O15040
SHLHRAMAHHEESVR

RHPN2P1

326

A8MT19
GASLDSHLHRMLHRD

SGSM1

686

Q2NKQ1
SMHTLDHLHGVSNRA

TTC17

956

Q96AE7
SHILSKHEESEMHVN

ZMYM5

616

Q9UJ78
AEHPEGHHDSALTHM

SLC30A5

176

Q8TAD4
HFHNRVSRIMIDDHN

TPTE2

276

Q6XPS3
AFHQEHEVRMSHLED

SUN1

426

O94901
MRDLHHGSNAHTALV

USP2

301

O75604
HTHGREMLDIFVHQL

TMEM45A

141

Q9NWC5
EDVADVHMLVHSPAH

UHRF1BP1

811

Q6BDS2
QRAHLAHHERIHTME

ZNF583

531

Q96ND8
IGHVEHMVHDSVVEA

ZFY

146

P08048
SSSHFRLHERTHMGE

ZNF14

626

P17017
GTMHELVNHVTVEHV

ZIC5

436

Q96T25
HLHHDAGIMRNETET

GOLGB1

2686

Q14789
DNIMSFDSHSHHERV

NEUROD1

331

Q13562