Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

CCDC88C EGF RASGRF2 DOCK8 ARHGAP31 GNB5 LRRK2 ADGRB3 PLEKHG2 TBC1D17

1.04e-045079110GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

CCDC88C EGF RASGRF2 DOCK8 ARHGAP31 GNB5 LRRK2 ADGRB3 PLEKHG2 TBC1D17

1.04e-045079110GO:0030695
GeneOntologyBiologicalProcessintermediate filament cytoskeleton organization

EPPK1 KRT18 SYNM KRT84 KRT85 PLEC

5.36e-0699926GO:0045104
GeneOntologyBiologicalProcessintermediate filament-based process

EPPK1 KRT18 SYNM KRT84 KRT85 PLEC

5.68e-06100926GO:0045103
GeneOntologyBiologicalProcesspositive regulation of protein autoubiquitination

MTA1 LRRK2

5.89e-053922GO:1902499
GeneOntologyBiologicalProcessnegative regulation of organelle assembly

LRRK2 RBM14 CDK5RAP2 WDR44

8.52e-0552924GO:1902116
GeneOntologyCellularComponentsupramolecular fiber

SLAIN2 MYH3 SYNPO2 MTA1 EPPK1 KRT18 CLIP2 SYNM KRT84 KRT85 PPP1R12B FBF1 CDK5RAP2 KIF4B PLEC WDR44

5.16e-0511799216GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

SLAIN2 MYH3 SYNPO2 MTA1 EPPK1 KRT18 CLIP2 SYNM KRT84 KRT85 PPP1R12B FBF1 CDK5RAP2 KIF4B PLEC WDR44

5.60e-0511879216GO:0099081
GeneOntologyCellularComponentintermediate filament

EPPK1 KRT18 SYNM KRT84 KRT85 FBF1 PLEC

6.50e-05227927GO:0005882
GeneOntologyCellularComponentkeratin filament

EPPK1 KRT18 KRT84 KRT85 FBF1

6.93e-0597925GO:0045095
GeneOntologyCellularComponentanchoring junction

CCDC88C DCHS2 TRIM15 SYNPO2 EPPK1 KRT18 SYNM ARHGAP31 FBF1 NECTIN4 PCDHA10 ITGA3 PLEC FRMD5

8.98e-059769214GO:0070161
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

SLAIN2 MTA1 EPPK1 KRT18 CLIP2 SYNM KRT84 KRT85 FBF1 CDK5RAP2 KIF4B PLEC WDR44

1.52e-048999213GO:0099513
GeneOntologyCellularComponentintermediate filament cytoskeleton

EPPK1 KRT18 SYNM KRT84 KRT85 FBF1 PLEC

1.62e-04263927GO:0045111
GeneOntologyCellularComponentmicrotubule plus-end

SLAIN2 CLIP2 CDK5RAP2

2.50e-0428923GO:0035371
GeneOntologyCellularComponentmicrotubule end

SLAIN2 CLIP2 CDK5RAP2

6.22e-0438923GO:1990752
GeneOntologyCellularComponenthemidesmosome

EPPK1 PLEC

1.03e-0311922GO:0030056
GeneOntologyCellularComponentcell-cell junction

CCDC88C DCHS2 EPPK1 KRT18 SYNM FBF1 NECTIN4 PCDHA10 FRMD5

1.17e-03591929GO:0005911
DomainCA

FREM2 DCHS2 PCDHA10 PCDH7 PCDHB16

2.47e-04115915SM00112
DomainIntermediate_filament_CS

KRT18 SYNM KRT84 KRT85

2.52e-0463914IPR018039
DomainCadherin

FREM2 DCHS2 PCDHA10 PCDH7 PCDHB16

2.79e-04118915IPR002126
Domain-

EPPK1 PLEC

3.48e-0469123.90.1290.10
DomainFilament

KRT18 SYNM KRT84 KRT85

3.99e-0471914SM01391
DomainIF

KRT18 SYNM KRT84 KRT85

4.21e-0472914PS00226
DomainFilament

KRT18 SYNM KRT84 KRT85

4.44e-0473914PF00038
DomainPlectin_repeat

EPPK1 PLEC

4.85e-047912IPR001101
DomainPlectin

EPPK1 PLEC

4.85e-047912PF00681
DomainPLEC

EPPK1 PLEC

4.85e-047912SM00250
DomainIF

KRT18 SYNM KRT84 KRT85

5.18e-0476914IPR001664
DomainCadherin_CS

DCHS2 PCDHA10 PCDH7 PCDHB16

1.99e-03109914IPR020894
DomainCADHERIN_1

DCHS2 PCDHA10 PCDH7 PCDHB16

2.27e-03113914PS00232
DomainCadherin

DCHS2 PCDHA10 PCDH7 PCDHB16

2.27e-03113914PF00028
DomainCADHERIN_2

DCHS2 PCDHA10 PCDH7 PCDHB16

2.34e-03114914PS50268
Domain-

DCHS2 PCDHA10 PCDH7 PCDHB16

2.34e-031149142.60.40.60
DomainCadherin-like

DCHS2 PCDHA10 PCDH7 PCDHB16

2.49e-03116914IPR015919
DomainCadherin_2

PCDHA10 PCDH7 PCDHB16

3.93e-0365913PF08266
DomainCadherin_N

PCDHA10 PCDH7 PCDHB16

3.93e-0365913IPR013164
DomainQuino_amine_DH_bsu

LRRK2 ANAPC4

5.09e-0322912IPR011044
DomainPH

SPTBN5 RASGRF2 OSBPL5 PLEKHG2 CIT

5.25e-03229915PF00169
DomainActinin_actin-bd_CS

SPTBN5 PLEC

5.56e-0323912IPR001589
DomainACTININ_2

SPTBN5 PLEC

5.56e-0323912PS00020
DomainACTININ_1

SPTBN5 PLEC

5.56e-0323912PS00019
DomainZnf_FYVE_PHD

KDM5B GNB5 SHPRH ZFYVE26

5.80e-03147914IPR011011
DomainKeratin_2_head

KRT84 KRT85

6.04e-0324912IPR032444
DomainKeratin_2_head

KRT84 KRT85

6.04e-0324912PF16208
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

VWA5B2 GRAMD2A CCDC88C DACT1 NADSYN1 EPPK1 SLC12A4 ANXA11 OSBPL5 UBL4A ZFYVE26 ITGA3 PLEC PLXNB2 CIT TBC1D17

3.72e-081105931635748872
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

SLAIN2 VPS37C ABLIM1 MTA1 EPPK1 RASGRF2 DOCK8 ARHGAP31 KRT84 UGGT1 RBM5 UBL4A PLEKHG2 PLEC

1.51e-07916931432203420
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

SLAIN2 KANSL1L DACT1 MYH3 ABLIM1 RASGRF2 RBM5 CDK5RAP2 SOCS6 PLEC

9.09e-07497931023414517
Pubmed

Pathological glycogenesis through glycogen synthase 1 and suppression of excessive AMP kinase activity in myeloid leukemia cells.

GYS1 PRKAA1

7.07e-06293225703587
Pubmed

Plakins in development and disease.

EPPK1 PLEC

7.07e-06293217499243
Pubmed

Interaction of FAM5C with UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1): Implication of N-glycosylation in FAM5C secretion.

BRINP3 UGGT1

7.07e-06293228351617
Pubmed

Cytokeratin 18-mediated disorganization of intermediate filaments is induced by degradation of plectin in human liver cells.

KRT18 PLEC

7.07e-06293221420381
Pubmed

Serum epidermal growth factor is associated with prognosis and hormone receptor status in patients with HER2-positive metastatic breast cancer treated with first-line trastuzumab plus taxane chemotherapy.

EGF PGR

7.07e-06293224036907
Pubmed

Hague (Hag). A new mouse hair mutation with an unstable semidominant allele.

KRT18 KRT84 KRT85

1.01e-051693312399393
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SLAIN2 ARHGAP31 FBF1 OSBPL5 ADGRB3 CDK5RAP2 GMEB2 KCNT1 EFR3A

1.26e-0552993914621295
Pubmed

Plakins: a family of versatile cytolinker proteins.

EPPK1 PLEC

2.12e-05393211854008
Pubmed

A functional role for AMPK in female fertility and endometrial regeneration.

PRKAA1 PGR

2.12e-05393230328345
Pubmed

AMPK is required for uterine receptivity and normal responses to steroid hormones.

PRKAA1 PGR

2.12e-05393232191914
Pubmed

Identification of the cytolinker plectin as a major early in vivo substrate for caspase 8 during CD95- and tumor necrosis factor receptor-mediated apoptosis.

KRT18 PLEC

2.12e-05393210891503
Pubmed

Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.

FREM2 MTA1 EPPK1 KRT18 XPC PLEC

2.81e-0521993631353912
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

NFE2L3 KDM5B DCHS2 ABLIM1 MTA1 CLIP2 SYNM CEP85L GNPTAB ADGRB3 XPC PLEC CIT

3.76e-051285931335914814
Pubmed

Histone demethylase KDM5B collaborates with TFAP2C and Myc to repress the cell cycle inhibitor p21(cip) (CDKN1A).

KDM5B TFAP2C

4.23e-05493222371483
Pubmed

Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP.

PRKAA1 LRRK2

4.23e-05493222012985
Pubmed

Leucine-rich repeat kinase 2 regulates tau phosphorylation through direct activation of glycogen synthase kinase-3β.

GYS1 LRRK2

4.23e-05493224165324
Pubmed

LRRK2 delays degradative receptor trafficking by impeding late endosomal budding through decreasing Rab7 activity.

EGF LRRK2

7.04e-05593225080504
Pubmed

Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene.

KRT18 KRT85

7.04e-05593211296228
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

ABLIM1 EPPK1 KRT18 KRT84 UGGT1 ANXA11 PRKAA1 RBM14 PLEC PLXNB2 CIT

9.21e-051024931124711643
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SLAIN2 CCDC88C KDM5B ABLIM1 KRT18 CEP85L RBM14 PLEKHG2 PLEC PCDH7

1.04e-04861931036931259
Pubmed

A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling.

EPPK1 KRT18 PLEC

1.04e-043493312577067
Pubmed

Characterization of human epiplakin: RNAi-mediated epiplakin depletion leads to the disruption of keratin and vimentin IF networks.

EPPK1 KRT18

1.05e-04693215671067
Pubmed

Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM.

SYNPO2 SYNM

1.05e-04693227470516
Pubmed

Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8.

ABCA4 ABCG8

1.05e-04693212111378
Pubmed

Epiplakin attenuates experimental mouse liver injury by chaperoning keratin reorganization.

EPPK1 KRT18

1.05e-04693225617501
Pubmed

Citron kinase interacts with LATS2 and inhibits its activity by occluding its hydrophobic phosphorylation motif.

ANXA11 TEAD3 CIT

1.70e-044093330865227
Pubmed

Differential regulation of estrogen receptor α expression in breast cancer cells by metastasis-associated protein 1.

MTA1 TFAP2C

1.96e-04893224413532
Pubmed

Cytokeratin, vimentin and E-cadherin immunodetection in the embryonic palate in two strains of mice with different susceptibility to glucocorticoid-induced clefting.

KRT18 KRT85

1.96e-04893211321598
Pubmed

SNPs in genes coding for ROS metabolism and signalling in association with docetaxel clearance.

EGF XPC

2.52e-04993220157331
Pubmed

Crucial role of fibroblasts in regulating epidermal morphogenesis.

EGF ITGA3

2.52e-04993212397374
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

EPPK1 RBM14 CDK5RAP2 PLEC CIT

2.58e-0421093516565220
Pubmed

Common variants at 1p36 are associated with superior frontal gyrus volume.

NFE2L3 RASGRF2

3.14e-041093225335168
Pubmed

Interaction of plectin with keratins 5 and 14: dependence on several plectin domains and keratin quaternary structure.

KRT18 PLEC

3.14e-041093224940650
Pubmed

A human MAP kinase interactome.

ABLIM1 SYNPO2 KRT18 CLIP2 ARHGAP31 PLEC WDR44

3.36e-0448693720936779
Pubmed

Antigen expression of human eccrine sweat glands.

EGF KRT18

3.83e-041193219032382
Pubmed

USP9X-mediated deubiquitination of B-cell CLL/lymphoma 9 potentiates Wnt signaling and promotes breast carcinogenesis.

EPPK1 PLEC

3.83e-041193231073027
Pubmed

The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha6beta4 and may regulate the spatial organization of hemidesmosomes.

ITGA3 PLEC

3.83e-041193210811835
Pubmed

Characterization of a 300 kbp region of human DNA containing the type II hair keratin gene domain.

KRT84 KRT85

4.59e-041293210692104
Pubmed

rec-YnH enables simultaneous many-by-many detection of direct protein-protein and protein-RNA interactions.

SLAIN2 MTA1 RBM14 RBM5

5.87e-0414293430217970
Pubmed

The Stat6-regulated KRAB domain zinc finger protein Zfp157 regulates the balance of lineages in mammary glands and compensates for loss of Gata-3.

KRT18 PGR

6.30e-041493222588720
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

EPPK1 KRT18 SYNM PLEC EFR3A

6.37e-0425693533397691
Pubmed

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

SLAIN2 CEP85L FBF1 CDK5RAP2

6.51e-0414693421399614
Pubmed

New consensus nomenclature for mammalian keratins.

KRT18 KRT84 KRT85

6.54e-046393316831889
Pubmed

EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.

SLAIN2 CDK5RAP2 PLEC

6.54e-046393329162697
Pubmed

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.

KRT18 UGGT1 SHPRH CHCHD6 CCDC51

7.07e-0426293536880596
Pubmed

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.

NOL4 PTCHD1 DOCK8 FBF1 PRKAA1 XPC

7.51e-0440293624722188
Pubmed

SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.

SLAIN2 ABLIM1 MICU3 ARHGAP31 KRT84 PLEC CIT

7.60e-0455893727591049
Pubmed

A unique role of cohesin-SA1 in gene regulation and development.

PCDH7 PCDHB16

8.28e-041693222415368
Pubmed

Suppression of C/EBPalpha expression in periportal hepatoblasts may stimulate biliary cell differentiation through increased Hnf6 and Hnf1b expression.

KRT18 ITGA3

8.28e-041693217021047
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

ABLIM1 UGGT1 RBM5 PLEC PCDH7

8.65e-0427493534244482
Pubmed

Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality.

PRKAA1 RBM14 RBM5

9.27e-047193336305789
Pubmed

Gpr125 is a unifying hallmark of multiple mammary progenitors coupled to tumor latency.

KRT18 PGR

9.37e-041793235302059
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

ABLIM1 CEP85L PPP1R12B UGGT1 UBL4A CDK5RAP2 CCDC51 CIT

9.48e-0475493833060197
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDHA10 PCDH7 PCDHB16

1.05e-037493310817752
Pubmed

Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction.

KRT18 GYS1

1.05e-031893231917811
Pubmed

Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.

SPTBN5 ITGA3

1.05e-031893212119179
Pubmed

Hemidesmosome integrity protects the colon against colitis and colorectal cancer.

KRT18 PLEC

1.05e-031893227371534
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ABLIM1 MTA1 FBXO4 RBM14 XPC PLEC PCDH7 WDR44

1.12e-0377493815302935
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

PCDHA10 PCDH7 PCDHB16

1.17e-037793310835267
Pubmed

Reduction of Nipbl impairs cohesin loading locally and affects transcription but not cohesion-dependent functions in a mouse model of Cornelia de Lange Syndrome.

PCDH7 PCDHB16

1.17e-031993223920377
Pubmed

Systematic Determination of Human Cyclin Dependent Kinase (CDK)-9 Interactome Identifies Novel Functions in RNA Splicing Mediated by the DEAD Box (DDX)-5/17 RNA Helicases.

ABLIM1 KRT18 RBM14 UQCRFS1 PLEC

1.20e-0329593526209609
Pubmed

Vhl safeguards thymic epithelial cell identity and thymopoietic capacity by constraining Hif1a activity during development.

KRT18 GYS1

1.30e-032093239040069
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDHA10 PCDH7 PCDHB16

1.31e-038093310716726
Pubmed

Docking motif-guided mapping of the interactome of protein phosphatase-1.

KDM5B PCIF1 CHCHD6

1.31e-038093319389623
Pubmed

AP-2 factors act in concert with Notch to orchestrate terminal differentiation in skin epidermis.

KRT18 TFAP2C

1.44e-032193218824566
Pubmed

EEF1D Promotes Glioma Proliferation, Migration, and Invasion through EMT and PI3K/Akt Pathway.

RBM14 PLEC

1.44e-032193233029523
Pubmed

A novel functional role for MMSET in RNA processing based on the link between the REIIBP isoform and its interaction with the SMN complex.

CCDC88C PLEC

1.44e-032193224923560
Pubmed

An Alternative Splicing Program for Mouse Craniofacial Development.

SLAIN2 MTA1

1.44e-032193233013468
Pubmed

The Angiocrine Factor Rspondin3 Is a Key Determinant of Liver Zonation.

KRT18 CYP2F1

1.44e-032193226655896
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

KDM5B KRT18 CEP85L KRT84 KRT85 GYS1 SHPRH UBL4A PLEC

1.49e-03100593919615732
Pubmed

Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene.

SLAIN2 ABLIM1

1.58e-032293222305495
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

NFE2L3 MYH3 SLC12A4 KRT18 KRT84 PPP1R12B UGGT1 FBF1 RBM5 XPC PLEC

1.62e-031442931135575683
Pubmed

Fras1, a basement membrane-associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli.

FREM2 ITGA3

1.73e-032393218787044
Pubmed

A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior.

PTCHD1 PGR

1.73e-032393235065713
Pubmed

Cytokinesis involves a nontranscriptional function of the Hippo pathway effector YAP.

PLEC TEAD3

1.73e-032393226933062
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

MYH3 EPPK1 KRT18 UGGT1 GCDH ITGA3 PLEC

1.78e-0364793726618866
Pubmed

Quantitative interaction proteomics of neurodegenerative disease proteins.

KDM5B EPPK1 ANXA11 UBL4A PLEC

1.79e-0332393525959826
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

MTA1 ABCA4 CMTM4 FBF1 AGPAT3 RBM14 CDK5RAP2 TEAD3 PLXNB2 CIT

1.80e-031242931030973865
Pubmed

USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c.

EPPK1 KRT18 PLEC

1.84e-039093335654790
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

ABLIM1 EPPK1 KRT18 SYNM KRT84 KRT85 UGGT1 RBM14 PLEC CIT

1.96e-031257931036526897
Pubmed

Ephrin-As, Eph receptors and integrin α3 interact and colocalise at membrane protrusions of U251MG glioblastoma cells.

MYH3 KRT85 UGGT1 ITGA3

1.97e-0319793423686814
Pubmed

VAPB/ALS8 interacts with FFAT-like proteins including the p97 cofactor FAF1 and the ASNA1 ATPase.

UBL4A WDR44

2.04e-032593224885147
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

TAPT1 SYNM UGGT1 UBL4A CDK5RAP2 CHCHD6 PLXNB2 PCDH7 TBC1D17 MAST3 EFR3A

2.06e-031487931133957083
Pubmed

Tagging genes with cassette-exchange sites.

KDM5B UGGT1 RBM5 PLEC CIT

2.09e-0333593515741177
Pubmed

Replication of a genome-wide case-control study of esophageal squamous cell carcinoma.

MYH3 ABCA4

2.38e-032793218649358
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

CCDC88C EPPK1 LRRK2 CDK5RAP2

2.40e-0320893433230847
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

ABLIM1 CLIP2 ADGRB3 PLEC CIT

2.44e-0334793517114649
Pubmed

A protein interaction framework for human mRNA degradation.

VWA5B2 NADSYN1 KRT18 XPC PLEKHG2

2.44e-0334793515231747
Pubmed

Discovery and refinement of loci associated with lipid levels.

RBM5 PLEC ABCG8 FRMD5

2.52e-0321193424097068
Pubmed

Abnormal neocortex arealization and Sotos-like syndrome-associated behavior in Setd2 mutant mice.

PCDHA10 PCDHB16

2.56e-032893233523829
Pubmed

BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization.

KRT18 PGR

2.56e-032893223103586
Pubmed

Synemin acts as a regulator of signalling molecules during skeletal muscle hypertrophy.

KRT18 SYNM

2.56e-032893225179606
GeneFamilyEF-hand domain containing|Plakins

EPPK1 PLEC

3.51e-048652939
CoexpressionAtlasgudmap_RNAseq_p2_CD2APMEISWT_2500_K1

FUT10 ABLIM1 FBXO4 SLC12A4 RASGRF2 CLIP2 ARHGAP31 GNB5 PRKAA1 AGPAT3 XPC IFT43 PCDHB16 MAST3

1.14e-058508914gudmap_RNAseq_p2_CD2APMEISWT_2500_K1
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_top-relative-expression-ranked_500

NFE2L3 MYH3 SYNPO2 KRT18 SYNM DOCK8 PPP1R12B PCDH7 TFAP2C

3.63e-05388899gudmap_developingLowerUrinaryTract_P1_bladder_500_J
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#4

NFE2L3 PTCHD1 KRT18 CMTM4 AGPAT3 NECTIN4 PLEC TEAD3

8.05e-05334898Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K4
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_top-relative-expression-ranked_1000

NFE2L3 FREM2 MYH3 SYNPO2 KRT18 SYNM DOCK8 PPP1R12B NECTIN4 PCDH7 TFAP2C WDR44

8.92e-057728912gudmap_developingLowerUrinaryTract_P1_bladder_1000_J
CoexpressionAtlasDevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#3_top-relative-expression-ranked_500

FREM2 SYNPO2 SYNM PPP1R12B PCDH7

1.23e-04115895gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_500_k3
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PTCHD1 SYNPO2 PPP1R12B ADGRB3 PLEKHG2 TEAD3 PGR

1.16e-07183937667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTCHD1 NECTIN4 C8orf74 ITGA3 TEAD3 CIT

1.55e-06170936a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FUT10 ARHGAP31 CEP85L LRRK2 SHPRH PCDH7

2.77e-061889366468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FUT10 ARHGAP31 CEP85L LRRK2 SHPRH PCDH7

2.77e-061889367a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FUT10 ARHGAP31 CEP85L LRRK2 SHPRH PCDH7

2.77e-061889369cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FREM2 PTCHD1 SYNPO2 SYNM PPP1R12B PCDH7

3.22e-061939360256e8fe4a47f2e2a43ef9d19bfc047d20806d69
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FREM2 PTCHD1 SYNPO2 SYNM PPP1R12B PCDH7

3.32e-06194936d2bafd31bb8333f66b6c714944bceb2f1aa11740
ToppCelldistal-Epithelial-Club|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PTCHD1 KRT18 CYP2F1 NECTIN4 CIT TFAP2C

3.84e-06199936c63ccce1285352927fd8c4f7374ec5fff8d70cec
ToppCellPND01-03-samps-Epithelial-Alveolar_epithelial-AT1_-_meso|PND01-03-samps / Age Group, Lineage, Cell class and subclass

GRAMD2A EPPK1 KRT18 OSBPL5 ITGA3

1.58e-051509356a13e4c4b9c9e54a5016573a37132465ec1c8f99
ToppCellAT1-AT2_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

KDM5B ABCA4 NECTIN4 TFAP2C FRMD5

2.03e-051589353bc51cfd37b289cc3e866b54ce55a298e5eff690
ToppCellClub_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

CYP2F1 OSBPL5 NECTIN4 ZSWIM1 PLXNB2

2.09e-05159935a7bcff268b1962a561fd2848e01ae16565bce895
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue|TCGA-Bladder / Sample_Type by Project: Shred V9

SYNPO2 MICU3 SYNM PPP1R12B PGR

2.16e-051609358a41e2c96e0e170ac35daf6c403bf961b8d7c30b
ToppCellTCGA-Bladder-Solid_Tissue_Normal|TCGA-Bladder / Sample_Type by Project: Shred V9

SYNPO2 MICU3 SYNM PPP1R12B PGR

2.16e-05160935d6678996e12eaf2b735f1dfae32418cb2fabf268
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue|TCGA-Bladder / Sample_Type by Project: Shred V9

SYNPO2 MICU3 SYNM PPP1R12B PGR

2.16e-05160935c8dc575562b463fd30832d322c28006f18f7ab9c
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FUT10 BRINP3 SYNPO2 PPP1R12B WDR44

2.36e-051639351e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NFE2L3 ABCA4 KRT18 KCNT1 FRMD5

3.14e-05173935ee7d1429f23f1b89a9a9f7bc07a84a44cf7acd1c
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BRINP3 SYNPO2 SYNM PPP1R12B PCDH7

3.14e-05173935cb6389536195443633adb06e5f1b7483530773d1
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NFE2L3 ABCA4 KRT18 KCNT1 FRMD5

3.14e-051739353725525b99a6011eda2ff5459b4fd2e1eab1f090
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)-|368C / Donor, Lineage, Cell class and subclass (all cells)

EGF KRT18 LRRK2 NECTIN4 CIT

3.50e-05177935ac8f774596068e66c0a9ea8a318be0ce5f5df834
ToppCellfacs-BAT-Fat-3m-Epithelial|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2L3 EPPK1 KRT18 GYS1 GNB5

3.50e-051779353e42f6236962dd9bb23dc0d09b460ec8347d1056
ToppCellfacs-BAT-Fat-3m-Epithelial-epithelial_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2L3 EPPK1 KRT18 GYS1 GNB5

3.50e-05177935128186bc996784e670194c07c5352e69af5f6d68
ToppCellfacs-BAT-Fat-3m-Epithelial-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2L3 EPPK1 KRT18 GYS1 GNB5

3.50e-051779357480e522cfae3f5c6c62720083750f8273725ab5
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)|368C / Donor, Lineage, Cell class and subclass (all cells)

EGF KRT18 LRRK2 NECTIN4 CIT

3.50e-05177935d9c4a93b0e04a13bf39992dd1c1ec8df2c5f89fe
ToppCellFetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BRINP3 SYNPO2 PPP1R12B ADGRB3 PCDH7

3.89e-0518193525915e2500430a902db37d79a749ce2990b69810
ToppCellASK454-Epithelial|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

GRAMD2A ABLIM1 KRT18 ITGA3 PCDHB16

3.99e-05182935ab15316cff989b61ff397a866d7ca8b49c13e981
ToppCelldroplet-Heart-4Chambers-18m-Neuronal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2L3 FREM2 EPPK1 KRT18 ITGA3

4.10e-051839352df1611c8acccb2a6f233d3d68bd9df2381a7278
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTCHD1 SYNPO2 SYNM PPP1R12B PCDH7

4.10e-0518393561a73de857f4ae02dcba3af348f436f602b28ff2
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-ACTC+_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PTCHD1 SYNPO2 SYNM PPP1R12B TFAP2C

4.21e-0518493539168ca2bbf1369c9fe87c67f0aaff5e3cd03151
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN5 KRT85 FRMD5 MAST3 PGR

4.43e-0518693502fbb02c495e7d64c4ab50e42e5197782f2c0816
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 DOCK8 ADGRB3 PLEKHG2 KCNT1

4.54e-0518793548bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2L3 KDM5B KRT18 NECTIN4 TFAP2C

4.54e-05187935aa336fb568a24e12c0454265ddd71ed10a6614cf
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 DOCK8 ADGRB3 PLEKHG2 KCNT1

4.54e-05187935958402fcc78f4c7a7d13d659d776f3817137975f
ToppCell343B-Lymphocytic-ILC-ILC-1|343B / Donor, Lineage, Cell class and subclass (all cells)

NADSYN1 SLC12A4 CEP85L CDK5RAP2 SOCS6

4.66e-051889358f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 DOCK8 ADGRB3 PLEKHG2 KCNT1

4.78e-05189935fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFE2L3 BRINP3 KRT18 KRT85 ITGA3

4.78e-05189935319e42f6e2322208de78bc666fb2c074707eb4da
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FREM2 SYNPO2 SYNM PPP1R12B TFAP2C

4.90e-05190935e102622f05c7f3e1bd8b224ea159d57033793ee0
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FREM2 SYNPO2 SYNM PPP1R12B PCDH7

5.15e-05192935d0fb6885f023d55a2b7984c99db9c6463258f788
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FREM2 SYNPO2 SYNM PPP1R12B TEAD3

5.28e-05193935a402e736440684ebe123673b6b0c6fcd8fa057b2
ToppCellfacs-Tongue-nan-3m-Epithelial-keratinocyte|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLAIN2 KDM5B ABLIM1 EPPK1 NECTIN4

5.28e-0519393533437fdb417d78463caee14a9f0e094da1733829
ToppCellcellseq-Epithelial-Epithelial_Alveolar-Secretory/RAS-RAS|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KRT18 CYP2F1 NECTIN4 CIT TFAP2C

5.28e-05193935525e0de0f25f3308daf49e7d4c8774562f1f40ad
ToppCellcellseq-Epithelial-Epithelial_Alveolar-Secretory/RAS|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KRT18 CYP2F1 NECTIN4 CIT TFAP2C

5.28e-051939352d18f39615043dfbff120a00f6540ffa93082c83
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABLIM1 KRT18 ANXA11 ITGA3 PCDH7

5.41e-0519493546070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABLIM1 KRT18 ANXA11 ITGA3 PCDH7

5.41e-05194935abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-keratinocyte|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM5B ABLIM1 CYP2F1 AGPAT3 NECTIN4

5.54e-05195935c54b19e31efe2c9ae690062569da7c0f1120a1d8
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

ABLIM1 EGF LRRK2 ITGA3 CIT

5.68e-0519693504f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTCHD1 SYNPO2 PPP1R12B PCDH7 PGR

5.68e-051969351522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-secretory_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABLIM1 EPPK1 NECTIN4 CIT TFAP2C

5.68e-05196935547901c7a665770eff78eede69b8625b416c8186
ToppCell(5)_Fibroblasts-(5)_Fibroblast-K_(Pericytes)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

SYNPO2 KRT18 SYNM PPP1R12B ITGA3

5.68e-05196935541b1fcf509e362f6f48720046cb5378aaf7c591
ToppCell11.5-Distal-Epithelial-Secretory_progenitor|Distal / Age, Tissue, Lineage and Cell class

FREM2 EPPK1 KRT18 NECTIN4 TFAP2C

5.68e-051969352648d64b0e7b59ae78182d55f32699ceea37ff8d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTCHD1 SYNPO2 PPP1R12B PCDH7 PGR

5.68e-051969351c8294014713684b50885e638668f2ce75f357f0
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABLIM1 EPPK1 NECTIN4 CIT TFAP2C

5.68e-051969356e08d7ba67da161c2dca1a17c440ffb9d9b5bc3b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1L ABLIM1 KRT18 LRRK2 ITGA3

5.82e-051979357e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNPO2 SYNM PPP1R12B TEAD3 PCDH7

5.82e-0519793594a7270ea6d4b586f58875c9e4071ce0f683ef7e
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DACT1 CLIP2 PPP1R12B PCDH7 ABCG8

5.82e-0519793531c8d6e565bbdc37843ce871fe91845b0cc18a9f
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

ABCA4 KRT18 LRRK2 GCDH PLXNB2

5.82e-051979356b6504c47c309bac4f790e2f372d454bbdea49e8
ToppCelldistal-3-mesenchymal-Fibromyocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

VWA5B2 DACT1 BRINP3 SYNPO2 PCDH7

5.96e-05198935dc93886439a378a0c71e99acb8081bfb6b6d467b
ToppCelldistal-Epithelial-Club-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PTCHD1 KRT18 CYP2F1 NECTIN4 CIT

5.96e-05198935e56a5ffadfa4d1e34d34aec43eaf560cd80286e1
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BRINP3 SYNPO2 SYNM PPP1R12B PCDH7

5.96e-05198935e9f434bfd072e590fe44d518057ee5aa653038f3
ToppCelldistal-1-Epithelial-Club|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KRT18 CYP2F1 NECTIN4 CIT TFAP2C

6.10e-051999358f0a72a95d0310ef2324c6975495c294b5a47cc8
ToppCellsaliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABLIM1 KRT18 ANXA11 NECTIN4 PLXNB2

6.10e-05199935667e1a56c33a2681af8dc1b7dbc3a9858e2c3c05
ToppCellsaliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABLIM1 KRT18 ANXA11 NECTIN4 PLXNB2

6.10e-05199935245b37df56dfbbdbac88f0e2fc3dfa0ed1abd588
ToppCelldistal-3-Epithelial-Club|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PTCHD1 KRT18 CYP2F1 NECTIN4 CIT

6.10e-051999351a0c3506df2438f5be40a8ea72effe5f8ebd35c4
ToppCellsaliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway-squamous_epithelial_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABLIM1 KRT18 ANXA11 NECTIN4 PLXNB2

6.10e-051999352dae9db4d25f1a390134da2b6621564b274fe910
ToppCellsaliva-Mild-Moderate_progression_d12-25-Epithelial|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ABLIM1 KRT18 ANXA11 NECTIN4 PLXNB2

6.10e-05199935dbb33f0e151b150ba9ca4612973f8034c62e762b
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EGF CEP85L GNPTAB ADGRB3 FRMD5

6.25e-052009357c2d499af60654b7b28f172ac2c914ad49fb74b4
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-4|TCGA-Cervix / Sample_Type by Project: Shred V9

FREM2 ABCA4 CYP2F1 KCNT1

1.50e-041289343ca9ae69fb8cb7f8acb7540aa71778bc917da4df
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

VPS37C CMTM4 OSBPL5 KCNT1

2.62e-04148934c240d506151fa90c59f40008c5fb31984c6f6f8f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 SYNPO2 SLC12A4 CLIP2

2.75e-041509341270f33f9d7e46e55adf1a96e8beee858b95589d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 SYNPO2 SLC12A4 CLIP2

2.75e-04150934156118ce1d69522624196410cba18b8354cd0bb4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DACT1 MYH3 SYNPO2 ZSWIM1

2.82e-04151934ea62e92ccb984f44559b434f35c1c4450767c8f1
ToppCellP07-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

VWA5B2 GRAMD2A KRT18 GNPTAB

2.97e-041539345501095bcf73080872ae01128f21399f9cfc5dd1
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VPS37C SYNPO2 TAPT1 LRRK2

2.97e-041539346a2a2379238133ce0ad714af130ffe02dd317247
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VPS37C SYNPO2 TAPT1 LRRK2

2.97e-04153934faa442dd925b2b09919e93c492ccc3f19803ad24
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLAIN2 BRINP3 ABCA4 CMTM4

3.19e-04156934d411116d54add2d4fe649a97ac54cb94c085312f
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KRT18 NECTIN4 CHCHD6 PCDH7

3.27e-0415793410989c7046fc859f137c7cef3296508d4476f11f
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-cortical_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

PTPN5 NADSYN1 ITGA3 ZSWIM1

3.35e-041589341f94622186d8329357fa06785e03eeacf29ab1ce
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 CEP85L PLEKHG2 PGR

3.43e-041599345ca96db4281abb5f646150ccf36adc66ab201c78
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

ABLIM1 SYNPO2 CMTM4 PLEC

3.60e-04161934347edb0de10850b7d16c40945751033289289c9b
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 KRT18 TEAD3 TFAP2C

3.69e-041629343dc39db0d5f6f3d7bcc312a6bce7aaeb914138d1
ToppCellfacs-Thymus-Epithelium-3m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 KRT18 TEAD3 TFAP2C

3.69e-041629340a7138266054ea5954649c8b61ef93905d56b068
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 BRINP3 KRT18 LRRC53

3.69e-041629349f568836199a05f696294caac1ea3fa413984423
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 KRT18 TEAD3 TFAP2C

3.69e-0416293425323785dd33337bcefd05958a4a1a208a9ceb04
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar-Club_cell|PND07-28-samps / Age Group, Lineage, Cell class and subclass

EPPK1 KRT18 CYP2F1 FBF1

3.69e-04162934aed15eef32419b8a4e2afdb9776c2bf2802e96f1
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BRINP3 ANXA11 LRRK2 MAST3

3.77e-041639341e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BRINP3 ANXA11 LRRK2 MAST3

3.77e-04163934431221a41d396b09170476179590eaf8a55266d8
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FREM2 SYNPO2 PPP1R12B PCDH7

3.77e-04163934e526104a3a574ee860078ce7c049e7fec9443f37
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Basal_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

SPTBN5 DCHS2 FBF1 PCDH7

3.77e-04163934f21951e63188eb0c04675a8f81a0da495c26c007
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Brinp3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SPTBN5 MYH3 SLC12A4 ARHGAP31

3.77e-04163934b0aa4a620bd58011225b42ea6dda04e3101ba342
ToppCellTCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma-3|TCGA-Uterus / Sample_Type by Project: Shred V9

DOCK8 GNPTAB NECTIN4 TFAP2C

3.77e-04163934d64dd39b077105c73e570ccef70f0e74a2c586ac
ToppCell368C-Epithelial_cells-Epithelial-A_(AT2)-|368C / Donor, Lineage, Cell class and subclass (all cells)

FREM2 EPPK1 KRT18 LRRK2

3.86e-0416493485f53d184fa70e3eb1af655807f32b17ddbfb304
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

BRINP3 SYNPO2 ADGRB3 PCDH7

3.86e-04164934e3983f655cdba308fb192182829f17bef99ce0ba
ToppCell368C-Epithelial_cells-Epithelial-A_(AT2)|368C / Donor, Lineage, Cell class and subclass (all cells)

FREM2 EPPK1 KRT18 LRRK2

3.86e-04164934144ba070a1ede71684224cc6d4ead3b7e6a7b4c6
ToppCelldroplet-Fat-Scat-21m|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN5 KRT18 TFAP2C PGR

3.95e-041659343f0c2486ea357d10dad0b703cf75cc29bdd5b5cf
ToppCellPND01-03-samps-Epithelial-Alveolar_epithelial-AT1|PND01-03-samps / Age Group, Lineage, Cell class and subclass

GRAMD2A KRT18 CMTM4 ITGA3

3.95e-04165934b9b6b7b8cd65ba6948a5dd8b715cc7092e0be637
ToppCellICU-NoSEP-Lymphocyte-T_NK-CD4_Naive|ICU-NoSEP / Disease, Lineage and Cell Type

DACT1 ABLIM1 MICU3 RASGRF2

3.95e-041659343d2f6f91a5eee64d01366f35d2cc3cf9ac37ac16
ToppCellBAL-Mild-Myeloid-MoAM-MoAM5-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MICU3 EPPK1 SYNM TEAD3

4.04e-04166934006ced12f69ef13ddcba5a3891ddc7c18c384863
ToppCellBAL-Mild-Myeloid-MoAM-MoAM5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MICU3 EPPK1 SYNM TEAD3

4.04e-04166934ac28c8cac1e94be0c47fb862c5809c92cdaa11f3
ToppCellBAL-Mild-Myeloid-MoAM-MoAM5-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MICU3 EPPK1 SYNM TEAD3

4.04e-041669346bb3410e65c971acc458c472015afcec6de6e310
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DACT1 DCHS2 FBXO4 TFAP2C

4.04e-04166934c11dcf9705b85ac3da6ae86358f5ffd64ae8327e
ToppCellBAL-Mild-Myeloid-MoAM-MoAM5|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

MICU3 EPPK1 SYNM TEAD3

4.04e-04166934823ec03714884cb860a1260410feac8c536b6d06
Diseaseepilepsy (implicated_via_orthology)

SLC12A4 KIF4B ITGA3 CIT KCNT1

1.53e-04163915DOID:1826 (implicated_via_orthology)
Diseaseanxiety, vitamin D measurement

DOCK8 GNB5

1.96e-047912EFO_0004631, EFO_0005230
Diseasehigh grade glioma (is_implicated_in)

KDM5B NADSYN1 EGF

2.99e-0442913DOID:3070 (is_implicated_in)
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

NFE2L3 PCIF1 MAST3

3.91e-0446913EFO_0008317, EFO_0008596, EFO_0020943
Diseasephospholipids:total lipids ratio

NFE2L3 SLC12A4 PCIF1 ABCG8 FRMD5

7.01e-04227915EFO_0020946
Diseasesalicylurate measurement

SLAIN2 ABLIM1

7.18e-0413912EFO_0010532
Diseasefree cholesterol to total lipids in medium VLDL percentage

NFE2L3 PCIF1 ABCG8

7.36e-0457913EFO_0022284
Diseasesuperior frontal gyrus grey matter volume measurement

NFE2L3 RASGRF2

8.36e-0414912EFO_0006516
Diseasevery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

NFE2L3 SLC12A4 PCIF1 ABCG8 FRMD5

8.83e-04239915EFO_0008317, EFO_0020945
Diseasefree cholesterol to total lipids in small VLDL percentage

NFE2L3 PCIF1 ABCG8

1.63e-0375913EFO_0022287
DiseasePrimary microcephaly

CDK5RAP2 CIT

2.09e-0322912C0431350
DiseaseAutosomal Recessive Primary Microcephaly

CDK5RAP2 CIT

2.09e-0322912C3711387
Diseaseclinical and behavioural ideal cardiovascular health

BRINP3 ABCG8

2.28e-0323912EFO_0007654
Diseaseplatelet measurement

EPPK1 EGF DOCK8 LRRK2 PLEC

2.95e-03315915EFO_0005036

Protein segments in the cluster

PeptideGeneStartEntry
AASYFIDRDSTLRRL

BRINP3

181

Q76B58
LYRDTRSEDSTRRLF

ANAPC4

556

Q9UJX5
RSETDLLDIRSEYKR

ANXA11

461

P50995
QRDSRRSILLDTLYE

C8orf74

36

Q6P047
VSARRDAYRRSDLLL

TFAP2C

136

Q92754
ESRERSSLLASRYDS

ABLIM1

626

O14639
RAYASLFRELEETLA

ABCA4

1241

P78363
ELRRTVYLCTDDNLR

ADGRB3

1276

O60242
LYSTTRKERDRAREE

FBXO4

236

Q9UKT5
YVDLTSIDRRSREQE

ABCG8

321

Q9H221
LSDQRRYSLIDRSSA

CLIP2

966

Q9UDT6
LEEDLVSARRRSDLY

CIT

571

O14578
VSARRRSDLYESELR

CIT

576

O14578
RSDLYESELRESRLA

CIT

581

O14578
LDRIGSYLAERLSRD

EFR3A

51

Q14156
RRREEESFSLYSDQT

CDK5RAP2

616

Q96SN8
DRSREQYARDLAALE

GMEB2

306

Q9UKD1
RRLAELSDYRRLSES

RBM14

606

Q96PK6
SRFDYDDERLLTIIR

CYP2F1

186

P24903
DDATCRLYDLRADRE

GNB5

301

O14775
EESAREYLLSASRVL

PTPN5

271

P54829
RRRLRSESSYDIDNI

KANSL1L

761

A0AUZ9
SLNDRLASYLDRVRS

KRT18

86

P05783
EIATYRRLLEGEESR

KRT84

461

Q9NSB2
SRFEDNEELRYSLRS

GNPTAB

321

Q3T906
EESSFLRRLYEEEIR

KRT85

251

P78386
RTEDISSDIFRRRYA

LRRC53

471

A6NM62
DDISLRRSYDRSSRS

KIAA1109

3816

Q2LD37
LRYTDLDTDDRELRY

FREM2

726

Q5SZK8
RLSLYRRSERQELSE

KCNT1

1111

Q5JUK3
LAADARSARAYRDEL

CCDC88C

301

Q9P219
RSARAYRDELDSLRE

CCDC88C

306

Q9P219
RLLDRTDSREAFEAY

PLXNB2

186

O15031
NITLAYTLEADRDRR

ITGA3

511

P26006
LDREQRDSYELTLRV

PCDH7

266

O60245
LLRFSELISDDIRRY

PERCC1

86

A0A1W2PR82
RYLEDTDRNLSRDEQ

NFE2L3

526

Q9Y4A8
REYITSLDLSANELR

LRRK2

981

Q5S007
LERERSYELVRSAET

KDM5B

1451

Q9UGL1
EDLDLYATSRERRFR

MICU3

136

Q86XE3
DERESRSRRRDSDYK

RBM5

26

P52756
TALYLARAEDRDSGR

DCHS2

996

Q6V1P9
LVLDSALDRERVSAY

PCDHA10

406

Q9Y5I2
LAARTRQLLEDESYD

PGR

316

P06401
YTLVTERALDREARA

PCDHB16

401

Q9NRJ7
RSLEREYSCTVRLLD

FRMD5

11

Q7Z6J6
RLRRENEELSARYLS

FBF1

646

Q8TES7
DLDEELRYSLATSRA

IFT43

6

Q96FT9
SSAEISYEEALRRAR

DACT1

681

Q9NYF0
YAEAARRLIESRSAS

PCIF1

291

Q9H4Z3
RRSLRTILAYSEEDT

DOCK8

1571

Q8NF50
LARELERVDSGYRSA

GCDH

126

Q92947
YEESSRDVRSRRPAD

EGF

1071

P01133
RELASYIRRLDSDDR

FUT10

331

Q6P4F1
RDIDELRTTISDRYA

CEP85L

781

Q5SZL2
ERSEVDYGRRLSADI

MAST3

736

O60307
EETLSTLRYADRARK

KIF4B

321

Q2VIQ3
YILDRRFRSLDDSCS

GYS1

551

P13807
VSLLSRDSVYDLLRR

GRAMD2A

161

Q8IUY3
DLLSRAAVEEDAYSR

OSBPL5

411

Q9H0X9
EESLRQEYAATTSRR

SLAIN2

286

Q9P270
IGEDSTIARESYRDR

SYNM

461

O15061
RLDRVSREDSQYLEL

CCDC51

136

Q96ER9
EKRLRTAYLRAEDSE

CCDC51

161

Q96ER9
TNREELYDLLETLRR

PTCHD1

656

Q96NR3
YASVERLLERLTDLR

RASGRF2

641

O14827
LESREAELRRRDTFY

CHCHD6

141

Q9BRQ6
REVSEDRRQDLLSRY

EPPK1

2461

P58107
DVLFSSYLSEARRDE

EPPK1

2661

P58107
YREVSEDRRQDLLSR

EPPK1

2996

P58107
DVLFSSYLSEARRDE

EPPK1

3726

P58107
YREVSEDRRQDLLSR

EPPK1

4061

P58107
VLFSSYLSEARRDEL

EPPK1

4261

P58107
REVSEDRRQDLLSRY

EPPK1

4596

P58107
ALAAELYREVLRSSE

SHPRH

1041

Q149N8
QRSDYARELEELSER

MYH3

1136

P11055
YRRRDISSTLIALAD

MTA1

46

Q13330
YRESAAFLLRSADEL

NOL4

616

O94818
RHSALRLESLYSDEE

SLC12A4

956

Q9UP95
SRDYGRDEAATLRLI

SPTBN5

1651

Q9NRC6
DSRTYLLDFRSIDDE

PRKAA1

466

Q13131
DYIRARTESRDVDSR

CMTM4

186

Q8IZR5
YRSLIERDVSRTDRT

TBC1D17

371

Q9HA65
YRRLEVLDSTKSSRE

UQCRFS1

91

P47985
DRDTVVEGLRRLSDY

AGPAT3

151

Q9NRZ7
YDSSERIASRDERIS

SYNPO2

661

Q9UMS6
QDRTIASSRLRLLEY

TEAD3

216

Q99594
YRDRLRSRLEALSTE

TRIM15

126

Q9C019
SNDSRIRLYDLRDLS

WDR44

761

Q5JSH3
REDSSRKLRTDLYID

ARHGAP31

806

Q2M1Z3
DRLLSAERAVTGYRD

PLEC

3896

Q15149
SLSSAEYEARVRARR

VWA5B2

286

Q8N398
RDYERSLSRLTLDDI

UBL4A

121

P11441
LTETLGFYESDRRRE

TAPT1

46

Q6NXT6
ERTASRVRELARLYS

PLEKHG2

811

Q9H7P9
TTLERRFAIYSARDD

XPC

281

Q01831
EFERRYSTLRELADS

ZSWIM1

461

Q9BR11
EISRSNLSDRYQELR

VPS37C

61

A5D8V6
DDYFATLRELEATLR

ZFYVE26

2126

Q68DK2
FLVRDSSDDRYLLSL

SOCS6

406

O14544
NSRILTAERDYLDLT

UGGT1

696

Q9NYU2
RSSLEYRASSRLKEL

THEG

221

Q9P2T0
EDVRSYRAEISSRNL

NADSYN1

276

Q6IA69
TDSSVEAREKRRSYL

PPP1R12B

606

O60237
YEEELTLTRENSIRR

NECTIN4

386

Q96NY8