Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium ion binding	LRP2 F7 RGN FBN3 ADGRL4	5.49e-04	749	19	5	GO:0005509
GeneOntologyMolecularFunction	signaling receptor complex adaptor activity	GNB4 GNB1	1.19e-03	54	19	2	GO:0030159
GeneOntologyCellularComponent	heterotrimeric G-protein complex	GNB4 GNB1	5.08e-04	35	20	2	GO:0005834
GeneOntologyCellularComponent	GTPase complex	GNB4 GNB1	6.97e-04	41	20	2	GO:1905360
GeneOntologyCellularComponent	extrinsic component of cytoplasmic side of plasma membrane	GNB4 GNB1	1.30e-03	56	20	2	GO:0031234
Domain	EGF_Ca-bd_CS	LRP2 F7 FBN3 ADGRL4	1.98e-06	97	18	4	IPR018097
Domain	EGF_CA	LRP2 F7 FBN3 ADGRL4	2.15e-06	99	18	4	PS01187
Domain	ASX_HYDROXYL	LRP2 F7 FBN3 ADGRL4	2.23e-06	100	18	4	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	LRP2 F7 FBN3 ADGRL4	2.82e-06	106	18	4	IPR000152
Domain	EGF_CA	LRP2 F7 FBN3 ADGRL4	4.94e-06	122	18	4	SM00179
Domain	EGF-like_Ca-bd_dom	LRP2 F7 FBN3 ADGRL4	5.27e-06	124	18	4	IPR001881
Domain	Guanine_nucleotide-bd_bsu	GNB4 GNB1	8.76e-06	5	18	2	IPR016346
Domain	Gprotein_B	GNB4 GNB1	3.93e-05	10	18	2	IPR001632
Domain	EGF	LRP2 F7 FBN3 ADGRL4	6.51e-05	235	18	4	SM00181
Domain	EGF_3	LRP2 F7 FBN3 ADGRL4	6.51e-05	235	18	4	PS50026
Domain	EGF_CA	LRP2 FBN3 ADGRL4	7.32e-05	86	18	3	PF07645
Domain	EGF-like_dom	LRP2 F7 FBN3 ADGRL4	8.15e-05	249	18	4	IPR000742
Domain	EGF-like_CS	LRP2 F7 FBN3 ADGRL4	9.77e-05	261	18	4	IPR013032
Domain	EGF_2	LRP2 F7 FBN3 ADGRL4	1.04e-04	265	18	4	PS01186
Domain	EGF	LRP2 F7 FBN3	2.27e-04	126	18	3	PF00008
Domain	cEGF	LRP2 FBN3	2.81e-04	26	18	2	PF12662
Domain	cEGF	LRP2 FBN3	2.81e-04	26	18	2	IPR026823
Domain	-	LRP2 RGN	6.36e-04	39	18	2	2.120.10.30
Domain	6-blade_b-propeller_TolB-like	LRP2 RGN	8.85e-04	46	18	2	IPR011042
Domain	EGF_1	LRP2 F7 FBN3	1.76e-03	255	18	3	PS00022
Domain	G-protein_beta_WD-40_rep	GNB4 GNB1	2.99e-03	85	18	2	IPR020472
Domain	-	SEMA4B GNB4 GNB1	3.76e-03	333	18	3	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	SEMA4B GNB4 GNB1	3.82e-03	335	18	3	IPR015943
Domain	Growth_fac_rcpt_	LRP2 FBN3	9.71e-03	156	18	2	IPR009030
Domain	WD40_repeat_CS	GNB4 GNB1	1.07e-02	164	18	2	IPR019775
Pathway	REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR	GNB4 GNB1	2.31e-04	19	17	2	M926
Pathway	REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR	GNB4 GNB1	2.31e-04	19	17	2	MM15021
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_CDC42	GNB4 GNB1	2.57e-04	20	17	2	M27853
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_CDC42	GNB4 GNB1	2.57e-04	20	17	2	MM15572
Pathway	REACTOME_PRESYNAPTIC_FUNCTION_OF_KAINATE_RECEPTORS	GNB4 GNB1	2.84e-04	21	17	2	M27409
Pathway	REACTOME_PRESYNAPTIC_FUNCTION_OF_KAINATE_RECEPTORS	GNB4 GNB1	2.84e-04	21	17	2	MM15159
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_12	GNB4 GNB1	3.12e-04	22	17	2	M841
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_12	GNB4 GNB1	3.12e-04	22	17	2	MM15016
Pathway	KEGG_MEDICUS_REFERENCE_LPAR_GNB_G_RHO_SIGNALING_PATHWAY	GNB4 GNB1	3.41e-04	23	17	2	M47549
Pathway	REACTOME_ADRENALINE_NORADRENALINE_INHIBITS_INSULIN_SECRETION	GNB4 GNB1	3.41e-04	23	17	2	MM15033
Pathway	REACTOME_G_PROTEIN_ACTIVATION	GNB4 GNB1	3.72e-04	24	17	2	M13115
Pathway	REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR	GNB4 GNB1	3.72e-04	24	17	2	M18308
Pathway	REACTOME_G_PROTEIN_ACTIVATION	GNB4 GNB1	3.72e-04	24	17	2	MM14794
Pathway	REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR	GNB4 GNB1	3.72e-04	24	17	2	MM15088
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_AKT_SIGNALING_PATHWAY	GNB4 GNB1	3.72e-04	24	17	2	M47460
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA	GNB4 GNB1	4.04e-04	25	17	2	M14301
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_1	GNB4 GNB1	4.04e-04	25	17	2	M811
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_1	GNB4 GNB1	4.04e-04	25	17	2	MM15056
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA	GNB4 GNB1	4.37e-04	26	17	2	MM15017
Pathway	KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY	GNB4 GNB1	4.37e-04	26	17	2	M47561
Pathway	KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY	GNB4 GNB1	4.37e-04	26	17	2	M47562
Pathway	KEGG_MEDICUS_REFERENCE_CCR5_GNB_G_PLCB_G_PKC_SIGNALING_PATHWAY	GNB4 GNB1	4.37e-04	26	17	2	M47557
Pathway	KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_PI3K_AKT_SIGNALING_PATHWAY	GNB4 GNB1	4.37e-04	26	17	2	M47456
Pathway	REACTOME_GPER1_SIGNALING	GNB4 GNB1	4.72e-04	27	17	2	MM15664
Pathway	KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_ERK_SIGNALING_PATHWAY	GNB4 GNB1	4.72e-04	27	17	2	M47454
Pathway	REACTOME_ADRENALINE_NORADRENALINE_INHIBITS_INSULIN_SECRETION	GNB4 GNB1	5.08e-04	28	17	2	M10679
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_JNK_SIGNALING_PATHWAY	GNB4 GNB1	5.45e-04	29	17	2	M47466
Pathway	REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING	GNB4 GNB1	5.84e-04	30	17	2	M18193
Pathway	REACTOME_ACTIVATION_OF_G_PROTEIN_GATED_POTASSIUM_CHANNELS	GNB4 GNB1	5.84e-04	30	17	2	MM14542
Pathway	REACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS	GNB4 GNB1	6.24e-04	31	17	2	MM15094
Pathway	KEGG_MEDICUS_REFERENCE_CCR2_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY	GNB4 GNB1	6.24e-04	31	17	2	M47540
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY	GNB4 GNB1	6.24e-04	31	17	2	M47541
Pathway	KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY	GNB4 GNB1	6.24e-04	31	17	2	M47554
Pathway	KEGG_MEDICUS_REFERENCE_CCR_CXCR_GNB_G_PI3K_RAC_SIGNALING_PATHWAY	GNB4 GNB1	6.24e-04	31	17	2	M47455
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_ERK_SIGNALING_PATHWAY	GNB4 GNB1	6.24e-04	31	17	2	M47459
Pathway	REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING	GNB4 GNB1	6.65e-04	32	17	2	M14309
Pathway	KEGG_MEDICUS_REFERENCE_GPCR_PI3K_SIGNALING_PATHWAY	GNB4 GNB1	6.65e-04	32	17	2	M47962
Pathway	REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS	GNB4 GNB1	6.65e-04	32	17	2	MM15148
Pathway	REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING	GNB4 GNB1	6.65e-04	32	17	2	MM15143
Pathway	REACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION	GNB4 GNB1	6.65e-04	32	17	2	MM14983
Pathway	REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS	GNB4 GNB1	6.65e-04	32	17	2	M861
Pathway	REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING	GNB4 GNB1	7.07e-04	33	17	2	MM15027
Pathway	REACTOME_SIGNAL_AMPLIFICATION	GNB4 GNB1	7.07e-04	33	17	2	MM15020
Pathway	REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS	GNB4 GNB1	7.07e-04	33	17	2	M10322
Pathway	REACTOME_SIGNAL_AMPLIFICATION	GNB4 GNB1	7.07e-04	33	17	2	M9379
Pathway	REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS	GNB4 GNB1	7.07e-04	33	17	2	MM15058
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNB_G_RHO_SIGNALING_PATHWAY	GNB4 GNB1	7.07e-04	33	17	2	M47550
Pathway	REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS	GNB4 GNB1	7.07e-04	33	17	2	MM15066
Pathway	REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION	GNB4 GNB1	7.07e-04	33	17	2	M11575
Pathway	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	GNB4 GNB1	7.96e-04	35	17	2	M1075
Pathway	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	GNB4 GNB1	8.42e-04	36	17	2	MM14544
Pathway	REACTOME_COOPERATION_OF_PDCL_PHLP1_AND_TRIC_CCT_IN_G_PROTEIN_BETA_FOLDING	GNB4 GNB1	9.38e-04	38	17	2	M27656
Pathway	REACTOME_CHAPERONIN_MEDIATED_PROTEIN_FOLDING	GNB4 GNB1	9.88e-04	39	17	2	MM15003
Pathway	REACTOME_AQUAPORIN_MEDIATED_TRANSPORT	GNB4 GNB1	1.04e-03	40	17	2	MM15115
Pathway	REACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION	GNB4 GNB1	1.15e-03	42	17	2	M791
Pathway	REACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS	GNB4 GNB1	1.20e-03	43	17	2	M933
Pathway	REACTOME_ADORA2B_MEDIATED_ANTI_INFLAMMATORY_CYTOKINES_PRODUCTION	GNB4 GNB1	1.20e-03	43	17	2	M29837
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	GNB4 GNB1	1.20e-03	43	17	2	M954
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	GNB4 GNB1	1.26e-03	44	17	2	MM15709
Pathway	REACTOME_CA2_PATHWAY	GNB4 GNB1	1.31e-03	45	17	2	MM15040
Pathway	REACTOME_GPER1_SIGNALING	GNB4 GNB1	1.31e-03	45	17	2	M45008
Pathway	REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS	GNB4 GNB1	1.49e-03	48	17	2	M10775
Pathway	REACTOME_AQUAPORIN_MEDIATED_TRANSPORT	GNB4 GNB1	1.75e-03	52	17	2	M920
Pathway	WP_VITAMIN_B12_METABOLISM	LRP2 F7	1.89e-03	54	17	2	M39337
Pathway	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	GNB4 GNB1	2.33e-03	60	17	2	MM14964
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	GNB4 GNB1	2.33e-03	60	17	2	M976
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	GNB4 GNB1	2.33e-03	60	17	2	MM15708
Pathway	REACTOME_REGULATION_OF_INSULIN_SECRETION	GNB4 GNB1	2.40e-03	61	17	2	MM15071
Pathway	REACTOME_CA2_PATHWAY	GNB4 GNB1	2.48e-03	62	17	2	M27321
Pathway	REACTOME_OPIOID_SIGNALLING	GNB4 GNB1	3.24e-03	71	17	2	MM14491
Pathway	REACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING	GNB4 GNB1	3.24e-03	71	17	2	MM15590
Pathway	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM	GNB4 GNB1	3.33e-03	72	17	2	MM14631
Pathway	REACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING	GNB4 GNB1	3.61e-03	75	17	2	M27874
Pathway	REACTOME_PLATELET_HOMEOSTASIS	GNB4 GNB1	3.70e-03	76	17	2	MM15051
Pathway	REACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS	GNB4 GNB1	3.80e-03	77	17	2	MM15044
Pathway	REACTOME_REGULATION_OF_INSULIN_SECRETION	GNB4 GNB1	3.90e-03	78	17	2	M1921
Pathway	REACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS	GNB4 GNB1	4.09e-03	80	17	2	M800
Pathway	REACTOME_PLATELET_HOMEOSTASIS	GNB4 GNB1	4.71e-03	86	17	2	M916
Pathway	REACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS	GNB4 KDM1B GNB1	5.01e-03	296	17	3	M27869
Pathway	REACTOME_OPIOID_SIGNALLING	GNB4 GNB1	5.15e-03	90	17	2	M6467
Pathway	REACTOME_VISUAL_PHOTOTRANSDUCTION	LRP2 GNB1	5.38e-03	92	17	2	MM14881
Pathway	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	GNB4 GNB1	5.61e-03	94	17	2	M797
Pathway	REACTOME_PROTEIN_FOLDING	GNB4 GNB1	6.08e-03	98	17	2	M776
Pathway	REACTOME_POTASSIUM_CHANNELS	GNB4 GNB1	6.08e-03	98	17	2	MM14545
Pathway	REACTOME_VISUAL_PHOTOTRANSDUCTION	LRP2 GNB1	6.32e-03	100	17	2	M27158
Pathway	PID_CXCR4_PATHWAY	SSH1 GNB1	6.32e-03	100	17	2	M124
Pathway	REACTOME_POTASSIUM_CHANNELS	GNB4 GNB1	6.69e-03	103	17	2	M1073
Pathway	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM	GNB4 GNB1	7.34e-03	108	17	2	M17034
Pathway	REACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING	GNB4 GNB1	9.43e-03	123	17	2	MM14988
Pathway	REACTOME_ESR_MEDIATED_SIGNALING	GNB4 GNB1	1.10e-02	133	17	2	MM15529
Pathway	REACTOME_ANTI_INFLAMMATORY_RESPONSE_FAVOURING_LEISHMANIA_PARASITE_INFECTION	GNB4 GNB1	1.11e-02	134	17	2	M29840
Pubmed	Diversity among the beta subunits of heterotrimeric GTP-binding proteins: characterization of a novel beta-subunit cDNA.	GNB4 GNB1	1.70e-06	4	19	2	1543505
Pubmed	The role of G protein beta subunits in the release of ATP from human erythrocytes.	GNB4 GNB1	1.70e-06	4	19	2	12512701
Pubmed	Gbeta gamma isoforms selectively rescue plasma membrane localization and palmitoylation of mutant Galphas and Galphaq.	GNB4 GNB1	2.82e-06	5	19	2	11294873
Pubmed	Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors.	GNB4 GNB1	4.24e-06	6	19	2	16371464
Pubmed	Identification of Gnr1p, a negative regulator of G alpha signalling in Schizosaccharomyces pombe, and its complementation by human G beta subunits.	GNB4 GNB1	4.24e-06	6	19	2	16884933
Pubmed	Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium.	GNB4 GNB1	5.93e-06	7	19	2	10570481
Pubmed	The gene for the beta-subunit of retinal transducin (Gnb-1) maps to distal mouse chromosome 4, and related sequences map to mouse chromosomes 5 and 8.	GNB4 GNB1	7.90e-06	8	19	2	2328987
Pubmed	Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11.	GNB4 GNB1	1.02e-05	9	19	2	10339615
Pubmed	Expression of olfactory receptors, G-proteins and AxCAMs during the development and maturation of olfactory sensory neurons in the mouse.	GNB4 GNB1	1.27e-05	10	19	2	9733924
Pubmed	Gβ2 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Neocortex.	GNB4 GNB1	1.27e-05	10	19	2	28334111
Pubmed	The G protein subunit gene families.	GNB4 GNB1	1.55e-05	11	19	2	10644457
Pubmed	A Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation.	GNB4 GNB1	1.55e-05	11	19	2	25982117
Pubmed	Specificities of Gβγ subunits for the SNARE complex before and after stimulation of α2a-adrenergic receptors.	GNB4 GNB1	1.55e-05	11	19	2	34932372
Pubmed	Human Multisubunit E3 Ubiquitin Ligase Required for Heterotrimeric G-Protein β-Subunit Ubiquitination and Downstream Signaling.	GNB4 GNB1	1.86e-05	12	19	2	34342229
Pubmed	Neural tube defects and impaired neural progenitor cell proliferation in Gbeta1-deficient mice.	GNB4 GNB1	1.86e-05	12	19	2	20186915
Pubmed	Differential sensitivity of P-Rex1 to isoforms of G protein betagamma dimers.	GNB4 GNB1	1.86e-05	12	19	2	16301321
Pubmed	Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families.	GNB4 GNB1	1.86e-05	12	19	2	8636150
Pubmed	The human G protein beta4 subunit: gene structure, expression, Ggamma and effector interaction.	GNB4 GNB1	2.20e-05	13	19	2	12782285
Pubmed	Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta.	GNB4 GNB1	2.96e-05	15	19	2	12486123
Pubmed	Role of molecular chaperones in G protein beta5/regulator of G protein signaling dimer assembly and G protein betagamma dimer specificity.	GNB4 GNB1	3.83e-05	17	19	2	19376773
Pubmed	Integral and associated lysosomal membrane proteins.	LRP2 GNB4 GNB1	4.31e-05	126	19	3	17897319
Pubmed	Characterization of 458 single nucleotide polymorphisms of disease candidate genes in the Korean population.	LRP2 F7	6.49e-05	22	19	2	12768436
Pubmed	KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression.	GNB4 GNB1	7.75e-05	24	19	2	23209302
Pubmed	Human transcription factor protein interaction networks.	LRP2 C15orf39 GNB4 KCMF1 KDM1B ZNF3	8.14e-05	1429	19	6	35140242
Pubmed	G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development.	GNB4 GNB1	1.06e-04	28	19	2	8858601
Pubmed	Purification and identification of G protein-coupled receptor protein complexes under native conditions.	GNB4 GNB1	1.30e-04	31	19	2	17215244
Pubmed	Multiple genes encoding zinc finger domains are expressed in human T cells.	ZNF17 ZNF3	1.30e-04	31	19	2	2288909
Pubmed	Glucagon and regulation of glucose metabolism.	GNB4 GNB1	1.30e-04	31	19	2	12626323
Pubmed	The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety.	GNB4 GNB1	2.52e-04	43	19	2	26487511
Interaction	GNGT2 interactions	GNB4 GNB1	5.53e-05	12	19	2	int:GNGT2
Interaction	GNG11 interactions	GNB4 GNB1	1.14e-04	17	19	2	int:GNG11
Interaction	RGS6 interactions	GNB4 GNB1	1.28e-04	18	19	2	int:RGS6
Interaction	GNG7 interactions	GNB4 GNB1	1.58e-04	20	19	2	int:GNG7
Interaction	GNG3 interactions	GNB4 GNB1	2.30e-04	24	19	2	int:GNG3
Interaction	GNG4 interactions	GNB4 GNB1	2.49e-04	25	19	2	int:GNG4
Interaction	GNGT1 interactions	GNB4 GNB1	2.70e-04	26	19	2	int:GNGT1
GeneFamily	Keratin associated proteins	KRTAP1-5 KRTAP21-3	3.59e-03	109	15	2	619
GeneFamily	WD repeat domain containing	GNB4 GNB1	1.94e-02	262	15	2	362
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_induced-Ectoderm_top-relative-expression-ranked_100	LRP2 FBN3 KLHL14	7.62e-05	99	18	3	PCBC_ECTO_100
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_induced-Ectoderm_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_100	LRP2 FBN3 KLHL14	7.62e-05	99	18	3	PCBC_ECTO_fibroblast_100
Disease	colorectal cancer, inflammatory bowel disease	BMP3 DTWD1	6.67e-05	19	19	2	EFO_0003767, MONDO_0005575
Disease	anorexia nervosa	LRP2 ADGRL4	9.24e-04	70	19	2	MONDO_0005351
Disease	Kidney Diseases	LRP2 RGN	1.45e-03	88	19	2	C0022658
Disease	Intellectual Disability	LRP2 TMEM94 GNB1	2.79e-03	447	19	3	C3714756
Disease	Global developmental delay	TMEM94 GNB1	3.28e-03	133	19	2	C0557874
Disease	Paroxysmal atrial fibrillation	GNB4 KDM1B	4.48e-03	156	19	2	C0235480
Disease	Persistent atrial fibrillation	GNB4 KDM1B	4.48e-03	156	19	2	C2585653
Disease	familial atrial fibrillation	GNB4 KDM1B	4.48e-03	156	19	2	C3468561
Disease	Atrial Fibrillation	GNB4 KDM1B	4.70e-03	160	19	2	C0004238
Disease	vital capacity	LRP2 FBN3 ADGRL4 GNB1	7.17e-03	1236	19	4	EFO_0004312
Disease	optic disc size measurement	LRP2 BMP3	7.60e-03	205	19	2	EFO_0004832

Protein segments in the cluster

Peptide	Gene	Start	Entry
TNTEGSYYCMCVPGF	ADGRL4	76	Q9HBW9
SYYCMCVPGFRSSSN	ADGRL4	81	Q9HBW9
AYYCSGACQFPMPKS	BMP3	396	P12645
SYRCSCGQGYSLMPD	FBN3	1176	Q75N90
MTCCQTSFCGYPSFS	KRTAP1-5	1	Q9BYS1
MTCAYAPSGNYVACG	GNB4	101	Q9HAV0
TSFYCSCRPGYKLMS	LRP2	3131	P98164
CPSGYTGKYCEMAFS	LRP2	4401	P98164
SMGAYKSSTICYCPE	KLHL14	581	Q9P2G3
SAYYPDCVGMSPSCT	KDM1B	221	Q8NB78
MTCAYAPSGNYVACG	GNB1	101	P62873
QSFTCPYCGKMGYTE	KCMF1	76	Q9P0J7
MYFNYKSVCGSCGFG	KRTAP21-3	1	Q3LHN1
CGGSRMFYCYTCYVP	DTWD1	61	Q8N5C7
YMFCAGYSDGSKDSC	F7	386	P08709
LFTCGTAAFSPMCTY	SEMA4B	146	Q9NPR2
TSCCFGGKNYSEMYV	RGN	246	Q15493
YKSCADCMYPTASGA	SSH1	646	Q8WYL5
CTYKGSYFSCPMAGT	C15orf39	41	Q6ZRI6
KPYECMECGGKFTYS	ZNF3	366	P17036
CLSGYCSAFAYKPMN	TMEM94	741	Q12767
GCNECGKYFMYSSAL	ZNF17	331	P17021