Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	brain-derived neurotrophic factor receptor signaling pathway	FAM72D FAM72A ATP1A3 FAM72B	1.33e-07	14	72	4	GO:0031547
GeneOntologyBiologicalProcess	regulation of brain-derived neurotrophic factor-activated receptor activity	FAM72D FAM72A FAM72B	1.63e-07	4	72	3	GO:0031551
GeneOntologyBiologicalProcess	negative regulation of brain-derived neurotrophic factor receptor signaling pathway	FAM72D FAM72A FAM72B	4.06e-07	5	72	3	GO:0031549
GeneOntologyBiologicalProcess	regulation of brain-derived neurotrophic factor receptor signaling pathway	FAM72D FAM72A FAM72B	1.41e-06	7	72	3	GO:0031548
MousePheno	polycystic kidney	FAM72D DCTN5 JADE3 FAM72A PLEKHM1 FAM72B	1.38e-06	92	54	6	MP:0008528
MousePheno	abnormal somatic hypermutation frequency	FAM72D FAM72A FAM72B	5.05e-05	19	54	3	MP:0004815
MousePheno	kidney cyst	FAM72D DCTN5 JADE3 FAM72A PLEKHM1 FAM72B	5.91e-05	177	54	6	MP:0003675
MousePheno	abnormal conjunctiva goblet cell morphology	THBS1 MUC5AC	8.74e-05	4	54	2	MP:0012164
MousePheno	increased B cell apoptosis	FAM72D FAM72A FAM72B	1.67e-04	28	54	3	MP:0008782
Domain	FAM72	FAM72D FAM72A FAM72B	2.01e-07	4	70	3	PF14976
Domain	FAM72	FAM72D FAM72A FAM72B	2.01e-07	4	70	3	IPR026768
Domain	EPHD	KMT2C JADE3 JADE1 MLLT10	1.26e-06	22	70	4	PS51805
Domain	PHD	KMT2C JADE3 NSD2 JADE1 MLLT10	9.01e-06	75	70	5	PF00628
Domain	TIL	VWF MUC19 MUC5AC	1.08e-05	12	70	3	PF01826
Domain	C8	VWF MUC19 MUC5AC	1.08e-05	12	70	3	PF08742
Domain	Znf_PHD-finger	KMT2C JADE3 NSD2 JADE1 MLLT10	1.16e-05	79	70	5	IPR019787
Domain	VWC	THBS1 VWF MUC19 MUC5AC	1.21e-05	38	70	4	SM00214
Domain	VWFC_2	THBS1 VWF MUC19 MUC5AC	1.21e-05	38	70	4	PS50184
Domain	Unchr_dom_Cys-rich	VWF MUC19 MUC5AC	1.40e-05	13	70	3	IPR014853
Domain	C8	VWF MUC19 MUC5AC	1.40e-05	13	70	3	SM00832
Domain	TIL_dom	VWF MUC19 MUC5AC	1.78e-05	14	70	3	IPR002919
Domain	VWF_dom	THBS1 VWF MUC19 MUC5AC	1.82e-05	42	70	4	IPR001007
Domain	Znf_FYVE_PHD	KMT2C JADE3 NSD2 JADE1 MLLT10 PRDM14	1.86e-05	147	70	6	IPR011011
Domain	PHD	KMT2C JADE3 NSD2 JADE1 MLLT10	2.08e-05	89	70	5	SM00249
Domain	Znf_PHD	KMT2C JADE3 NSD2 JADE1 MLLT10	2.32e-05	91	70	5	IPR001965
Domain	VWD	VWF MUC19 MUC5AC	2.73e-05	16	70	3	SM00216
Domain	VWF_type-D	VWF MUC19 MUC5AC	2.73e-05	16	70	3	IPR001846
Domain	VWFD	VWF MUC19 MUC5AC	2.73e-05	16	70	3	PS51233
Domain	VWD	VWF MUC19 MUC5AC	2.73e-05	16	70	3	PF00094
Domain	ZF_PHD_2	KMT2C JADE3 NSD2 JADE1 MLLT10	2.85e-05	95	70	5	PS50016
Domain	ZF_PHD_1	KMT2C JADE3 NSD2 JADE1 MLLT10	3.00e-05	96	70	5	PS01359
Domain	CTCK_1	VWF MUC19 MUC5AC	3.95e-05	18	70	3	PS01185
Domain	VWC_out	VWF MUC19 MUC5AC	4.68e-05	19	70	3	SM00215
Domain	CT	VWF MUC19 MUC5AC	7.38e-05	22	70	3	SM00041
Domain	LamGL	PAPPA2 USH2A	8.27e-05	4	70	2	SM00560
Domain	LamG-like	PAPPA2 USH2A	8.27e-05	4	70	2	IPR006558
Domain	Zinc_finger_PHD-type_CS	JADE3 NSD2 JADE1 MLLT10	1.03e-04	65	70	4	IPR019786
Domain	Cys_knot_C	VWF MUC19 MUC5AC	1.09e-04	25	70	3	IPR006207
Domain	CTCK_2	VWF MUC19 MUC5AC	1.09e-04	25	70	3	PS01225
Domain	VWC	THBS1 VWF MUC5AC	1.54e-04	28	70	3	PF00093
Domain	Znf_C2H2	ZNF10 GTF2H2 FEZF1 ZNF175 GLI2 ZNF611 ZNF480 ZNF57 PRDM14 ZNF239 ZNF557	1.88e-04	805	70	11	IPR007087
Domain	-	ZNF10 FEZF1 ZNF175 GLI2 ZNF611 ZNF480 ZNF57 PRDM14 ZNF239 ZNF557	2.09e-04	679	70	10	3.30.160.60
Domain	zf-C2H2	ZNF10 FEZF1 ZNF175 GLI2 ZNF611 ZNF480 ZNF57 PRDM14 ZNF239 ZNF557	2.46e-04	693	70	10	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF10 FEZF1 ZNF175 GLI2 ZNF611 ZNF480 ZNF57 PRDM14 ZNF239 ZNF557	2.49e-04	694	70	10	IPR013087
Domain	VWFC_1	THBS1 VWF MUC5AC	3.29e-04	36	70	3	PS01208
Domain	EPL1	JADE3 JADE1	3.82e-04	8	70	2	PF10513
Domain	Enhancer_polycomb-like_N	JADE3 JADE1	3.82e-04	8	70	2	IPR019542
Domain	Somatomedin_B	TINAG ENPP2	3.82e-04	8	70	2	PF01033
Domain	Pectin_lyase_fold/virulence	FBXO11 CEMIP2	3.82e-04	8	70	2	IPR011050
Domain	EGF_1	THBS1 EYS SCUBE2 LAMC2 USH2A LRP1B	3.86e-04	255	70	6	PS00022
Domain	-	PAPPA2 THBS1 EYS USH2A	4.45e-04	95	70	4	2.60.120.200
Domain	SET	KMT2C NSD2 PRDM14	4.85e-04	41	70	3	PF00856
Domain	SO	TINAG ENPP2	4.90e-04	9	70	2	SM00201
Domain	ZINC_FINGER_C2H2_2	ZNF10 FEZF1 ZNF175 GLI2 ZNF611 ZNF480 ZNF57 PRDM14 ZNF239 ZNF557	5.94e-04	775	70	10	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF10 FEZF1 ZNF175 GLI2 ZNF611 ZNF480 ZNF57 PRDM14 ZNF239 ZNF557	6.06e-04	777	70	10	PS00028
Domain	Somatomedin_B_dom	TINAG ENPP2	6.11e-04	10	70	2	IPR001212
Domain	SMB_1	TINAG ENPP2	6.11e-04	10	70	2	PS00524
Domain	SMB_2	TINAG ENPP2	6.11e-04	10	70	2	PS50958
Domain	NHL	TRIM2 LRP1B	6.11e-04	10	70	2	PF01436
Domain	NHL_repeat	TRIM2 LRP1B	6.11e-04	10	70	2	IPR001258
Domain	SET	KMT2C NSD2 PRDM14	6.82e-04	46	70	3	SM00317
Domain	Znf_C2H2-like	ZNF10 FEZF1 ZNF175 GLI2 ZNF611 ZNF480 ZNF57 PRDM14 ZNF239 ZNF557	7.31e-04	796	70	10	IPR015880
Domain	ZnF_C2H2	ZNF10 FEZF1 ZNF175 GLI2 ZNF611 ZNF480 ZNF57 PRDM14 ZNF239 ZNF557	8.20e-04	808	70	10	SM00355
Domain	SET_dom	KMT2C NSD2 PRDM14	8.71e-04	50	70	3	IPR001214
Domain	SET	KMT2C NSD2 PRDM14	8.71e-04	50	70	3	PS50280
Domain	EGF_CA	THBS1 EYS SCUBE2 LRP1B	1.14e-03	122	70	4	SM00179
Domain	EGF-like_Ca-bd_dom	THBS1 EYS SCUBE2 LRP1B	1.21e-03	124	70	4	IPR001881
Domain	Laminin_G	THBS1 EYS USH2A	1.34e-03	58	70	3	IPR001791
Domain	ConA-like_dom	PAPPA2 THBS1 EYS MDGA1 USH2A	1.38e-03	219	70	5	IPR013320
Domain	-	KMT2C TRIM2 JADE3 NSD2 JADE1 MLLT10 ZFPL1	1.44e-03	449	70	7	3.30.40.10
Domain	Post-SET_dom	KMT2C NSD2	1.61e-03	16	70	2	IPR003616
Domain	PostSET	KMT2C NSD2	1.61e-03	16	70	2	SM00508
Domain	POST_SET	KMT2C NSD2	1.61e-03	16	70	2	PS50868
Domain	Znf_RING/FYVE/PHD	KMT2C TRIM2 JADE3 NSD2 JADE1 MLLT10 ZFPL1	1.63e-03	459	70	7	IPR013083
Domain	C1	KMT2C PRKCE PLEKHM1	1.86e-03	65	70	3	SM00109
Domain	EGF	THBS1 EYS SCUBE2 LAMC2 LRP1B	1.88e-03	235	70	5	SM00181
Domain	PE/DAG-bd	KMT2C PRKCE PLEKHM1	1.95e-03	66	70	3	IPR002219
Domain	KRAB	ZNF10 ZNF175 ZNF611 ZNF480 ZNF57 ZNF557	2.22e-03	358	70	6	PS50805
Domain	KRAB	ZNF10 ZNF175 ZNF611 ZNF480 ZNF57 ZNF557	2.22e-03	358	70	6	PF01352
Domain	EGF-like_dom	THBS1 EYS SCUBE2 LAMC2 LRP1B	2.42e-03	249	70	5	IPR000742
Domain	KRAB	ZNF10 ZNF175 ZNF611 ZNF480 ZNF57 ZNF557	2.58e-03	369	70	6	SM00349
Domain	KRAB	ZNF10 ZNF175 ZNF611 ZNF480 ZNF57 ZNF557	2.62e-03	370	70	6	IPR001909
Domain	Growth_fac_rcpt_	EYS SCUBE2 LAMC2 LRP1B	2.80e-03	156	70	4	IPR009030
Domain	EGF-like_CS	THBS1 EYS SCUBE2 LAMC2 LRP1B	2.96e-03	261	70	5	IPR013032
Domain	EGF_2	THBS1 EYS SCUBE2 LAMC2 LRP1B	3.16e-03	265	70	5	PS01186
Pubmed	Fam72a enforces error-prone DNA repair during antibody diversification.	FAM72D FAM72A FAM72B	3.40e-08	4	72	3	34819671
Pubmed	Identification and characterisation of the novel amyloid-beta peptide-induced protein p17.	FAM72D FAM72A FAM72B	8.48e-08	5	72	3	19755123
Pubmed	All-or-(N)One - an epistemological characterization of the human tumorigenic neuronal paralogous FAM72 gene loci.	FAM72D FAM72A FAM72B	8.48e-08	5	72	3	26206078
Pubmed	FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation.	FAM72D FAM72A FAM72B	1.69e-07	6	72	3	34819670
Pubmed	Platr4 is an early embryonic lncRNA that exerts its function downstream on cardiogenic mesodermal lineage commitment.	THBS1 VWF LAMC2	3.05e-06	14	72	3	36347239
Pubmed	cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein.	FAM72D FAM72A FAM72B	3.80e-06	15	72	3	1741163
Pubmed	Relationship between thrombospondin gene variations, von Willebrand factor levels and the risk of coronary heart disease in an older population.	THBS1 VWF	4.23e-06	2	72	2	21518247
Pubmed	Thrombospondin-1 in von Willebrand factor function.	THBS1 VWF	4.23e-06	2	72	2	18855616
Pubmed	Interstitial macrophage-derived thrombospondin-1 contributes to hypoxia-induced pulmonary hypertension.	THBS1 EPAS1	4.23e-06	2	72	2	31710666
Pubmed	Role of thrombospondin-1 in control of von Willebrand factor multimer size in mice.	THBS1 VWF	4.23e-06	2	72	2	14981081
Pubmed	Hypoxia Increases ATX Expression by Histone Crotonylation in a HIF-2α-Dependent Manner.	ENPP2 EPAS1	4.23e-06	2	72	2	37108194
Pubmed	Thrombospondin 1 requires von Willebrand factor to modulate arterial thrombosis in mice.	THBS1 VWF	4.23e-06	2	72	2	25343959
Pubmed	Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosis.	VWF STXBP5	4.23e-06	2	72	2	21163921
Pubmed	Identification of Jade1, a gene encoding a PHD zinc finger protein, in a gene trap mutagenesis screen for genes involved in anteroposterior axis development.	JADE3 JADE1	1.27e-05	3	72	2	14612400
Pubmed	Association between variations in coagulation system genes and carotid plaque.	THBS1 VWF	1.27e-05	3	72	2	22982001
Pubmed	Evaluating von Willebrand factor and ADAMTS13 levels in thalassemia major patients and assessing a possible association with Thrombospondin-1.	THBS1 VWF	1.27e-05	3	72	2	37438087
Pubmed	Thrombospondin-1 and ADAMTS13 competitively bind to VWF A2 and A3 domains in vitro.	THBS1 VWF	1.27e-05	3	72	2	20705333
Pubmed	P-selectin can promote thrombus propagation independently of both von Willebrand factor and thrombospondin-1 in mice.	THBS1 VWF	1.27e-05	3	72	2	27943541
Pubmed	CLEC4M and STXBP5 gene variations contribute to von Willebrand factor level variation in von Willebrand disease.	VWF STXBP5	1.27e-05	3	72	2	25832887
Pubmed	KMT2C Induced by FABP5P3 Aggravates Keratinocyte Hyperproliferation and Psoriasiform Skin Inflammation by Upregulating the Transcription of PIK3R3.	KMT2C PIK3R3	1.27e-05	3	72	2	35870559
Pubmed	A splice variant of the human ion channel TRPM2 modulates neuroblastoma tumor growth through hypoxia-inducible factor (HIF)-1/2α.	TRPM2 EPAS1	1.27e-05	3	72	2	25391657
Pubmed	A thrombospondin-dependent pathway for a protective ER stress response.	THBS1 CSRP3	2.53e-05	4	72	2	22682248
Pubmed	TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension.	THBS1 EPAS1	4.21e-05	5	72	2	28555642
Pubmed	Osteoprotegerin (OPG) is localized to the Weibel-Palade bodies of human vascular endothelial cells and is physically associated with von Willebrand factor.	THBS1 VWF	4.21e-05	5	72	2	15799029
Pubmed	Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.	MUC19 MUC5AC	6.31e-05	6	72	2	19110483
Pubmed	Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium.	VWF STXBP5	6.31e-05	6	72	2	20231535
Pubmed	Distinctive functions of membrane type 1 matrix-metalloprotease (MT1-MMP or MMP-14) in lung and submandibular gland development are independent of its role in pro-MMP-2 activation.	VWF LAMC2	6.31e-05	6	72	2	15572153
Pubmed	HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction.	THBS1 EPAS1	6.31e-05	6	72	2	26503986
Pubmed	Impact on venous thrombosis risk of newly discovered gene variants associated with FVIII and VWF plasma levels.	VWF STXBP5	8.82e-05	7	72	2	21029358
Pubmed	Thbs1 induces lethal cardiac atrophy through PERK-ATF4 regulated autophagy.	THBS1 CSRP3	8.82e-05	7	72	2	34168130
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RALGAPA1 KMT2C JADE3 NSD2 JADE1 HERC4 CEMIP2	1.14e-04	529	72	7	14621295
Pubmed	Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma.	KMT2C FBXO11	1.88e-04	10	72	2	22421440
Pubmed	The centrosomal deubiquitylase USP21 regulates Gli1 transcriptional activity and stability.	SLF1 GLI2	2.30e-04	11	72	2	27621083
Pubmed	Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma.	FBXO11 USH2A	2.30e-04	11	72	2	24349473
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	THBS1 TINAG VWF LAMC2	4.09e-04	167	72	4	22159717
Pubmed	Sox9 in mouse urogenital sinus epithelium mediates elongation of prostatic buds and expression of genes involved in epithelial cell migration.	THBS1 EPAS1	4.98e-04	16	72	2	31669249
Pubmed	Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development.	GLI2 LAMC2	4.98e-04	16	72	2	12533516
Pubmed	The Poly(C) Binding Protein Pcbp2 and Its Retrotransposed Derivative Pcbp1 Are Independently Essential to Mouse Development.	THBS1 VWF	4.98e-04	16	72	2	26527618
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	RALGAPA1 STXBP5 OSBPL1A SNX19 PLEKHM1 CEMIP2	6.26e-04	504	72	6	34432599
Pubmed	Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.	MUC19 MUC5AC	6.33e-04	18	72	2	18834073
Pubmed	Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels.	VWF STXBP5	6.33e-04	18	72	2	21810271
Pubmed	Cyclin F-mediated degradation of ribonucleotide reductase M2 controls genome integrity and DNA repair.	FBXW4 FBXO11	7.84e-04	20	72	2	22632967
Pubmed	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	EYS USH2A LRP1B EPAS1	7.89e-04	199	72	4	23382691
Pubmed	KAT7/HBO1/MYST2 Regulates CENP-A Chromatin Assembly by Antagonizing Suv39h1-Mediated Centromere Inactivation.	JADE3 JADE1	8.65e-04	21	72	2	27270040
Pubmed	Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract.	GLI2 MUC5AC	9.50e-04	22	72	2	20430747
Pubmed	Genome-wide association study to identify single nucleotide polymorphisms (SNPs) associated with the development of erectile dysfunction in African-American men after radiotherapy for prostate cancer.	GLI2 LRP1B	1.04e-03	23	72	2	20932654
Pubmed	The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors.	VWF MSH3 SNX19	1.16e-03	99	72	3	19730683
Pubmed	DSCAM Deficiency Leads to Premature Spine Maturation and Autism-like Behaviors.	LRRTM1 MDGA1	1.33e-03	26	72	2	34848499
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	KMT2C FEZF1 PRDM14 PLEKHM1	1.41e-03	233	72	4	37704626
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	GTF2H2 ZNF175 JADE1 MLLT10 EPAS1 ZFPL1 ZNF239	1.42e-03	808	72	7	20412781
Pubmed	Analysis of the Tropism of SARS-CoV-2 Based on the Host Interactome of the Spike Protein.	THBS1 LAMC2	1.89e-03	31	72	2	37939376
Pubmed	Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination.	ENPP2 PIK3R3	2.01e-03	32	72	2	26928066
GeneFamily	PHD finger proteins	KMT2C JADE3 NSD2 JADE1 MLLT10	5.36e-06	90	51	5	88
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF10 FEZF1 ZNF175 GLI2 ZNF611 ZNF480 ZNF57 PRDM14 ZNF239 ZNF557	2.68e-05	718	51	10	28
GeneFamily	CD molecules\|Mucins	MUC19 MUC5AC	1.58e-03	21	51	2	648
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2C NSD2	4.13e-03	34	51	2	487
ToppCell	ASK454-Endothelial-Endothelium\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	VWF ENPP2 PIK3R3 ESAM PRKCE EPAS1 CEMIP2	3.10e-08	196	72	7	2b777a2026b56839112fd179f2db482c49f4594a
ToppCell	Control-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	VWF PIK3R3 ESAM PRKCE EPAS1 CEMIP2	6.50e-07	190	72	6	7f3f419fffe02934b6f27b697f7a6401072491ed
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWF SLF1 ENPP2 ESAM PRKCE EPAS1	7.12e-07	193	72	6	e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWF SLF1 ENPP2 ESAM PRKCE EPAS1	7.12e-07	193	72	6	6e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCell	ASK440-Endothelial-Endothelium\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	VWF ENPP2 PIK3R3 MUC19 ESAM EPAS1	7.56e-07	195	72	6	304f0dc91bb57e98b0ca31d6bfb3ff9364e4da56
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF PIK3R3 ESAM PRKCE EPAS1 CEMIP2	7.56e-07	195	72	6	667a2ed4b865e9a37674b3d154bb5bf2188b3ebf
ToppCell	ASK454-Endothelial\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	VWF PIK3R3 ESAM PRKCE EPAS1 CEMIP2	7.79e-07	196	72	6	14dd6956ef420b660be0baf52a66960e57d75d16
ToppCell	COPD-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	VWF PIK3R3 ESAM PRKCE EPAS1 CEMIP2	8.02e-07	197	72	6	30dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCell	Endothelial_cells-Endothelial-A\|Endothelial_cells / lung cells shred on cell class, cell subclass, sample id	VWF ENPP2 PIK3R3 ESAM EPAS1 CEMIP2	8.51e-07	199	72	6	2a1424c61ddcd1fea9574f7a3ad1955387458130
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF PIK3R3 ESAM PRKCE EPAS1 CEMIP2	8.76e-07	200	72	6	ec9a18576a3d08ddfceb70d114c4ab861fbb0d08
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KMT2C VWF SLF1 ENPP2 ESAM EPAS1	8.76e-07	200	72	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Transplant_Alveoli_and_parenchyma-Endothelial-Endothelial\|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X	VWF ENPP2 PIK3R3 ESAM EPAS1 CEMIP2	8.76e-07	200	72	6	2ae62c428728c1d9d4471d4be24bd6ab074fa22c
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF PIK3R3 ESAM PRKCE EPAS1 CEMIP2	8.76e-07	200	72	6	24e43d3d16d07571f77e0cd5b2e4758c6ff802cb
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_only / Treatment groups by lineage, cell group, cell type	VWF SLF1 ENPP2 ESAM PRKCE EPAS1	8.76e-07	200	72	6	b1fadb2b5e37e0f51e079d8409c2647eef68dc3b
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	VWF SLF1 ENPP2 ESAM PRKCE EPAS1	8.76e-07	200	72	6	89a6da2bdedc6b1ad0675c8753bf2b763a99af6a
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	VWF SLF1 ENPP2 ESAM PRKCE EPAS1	8.76e-07	200	72	6	58a7ece7dfdf6c46f2a50cbcb580574dec14c748
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	VWF CLCN1 EPAS1 FAM72B CEMIP2	7.37e-06	166	72	5	f7926ee266dcbf10df375cd921f1db5a2fa604f8
ToppCell	368C-Endothelial_cells-Endothelial-B_(Artery)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	VWF ENPP2 PIK3R3 ESAM EPAS1	9.01e-06	173	72	5	ec88e871b49331fca59bc610a8ae58e2d5e76bc1
ToppCell	368C-Endothelial_cells-Endothelial-B_(Artery)\|368C / Donor, Lineage, Cell class and subclass (all cells)	VWF ENPP2 PIK3R3 ESAM EPAS1	9.01e-06	173	72	5	22200fe74e33e2beae0eed289ca8476bbc0b1b2d
ToppCell	facs-Lung-Endomucin-24m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF ESAM LRP1B EPAS1 CEMIP2	9.27e-06	174	72	5	60a426bfe5625999f031776ab34f7bc0d2b331be
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF PIK3R3 ESAM EPAS1 CEMIP2	9.79e-06	176	72	5	27e6b3ae41068d6cfdda3d46da7df2a27567140e
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF PIK3R3 ESAM EPAS1 CEMIP2	9.79e-06	176	72	5	d6a5470af9592f34a741265f2ea9651c05c3add3
ToppCell	facs-Lung-EPCAM-18m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUGGC ESAM CSRP3 EPAS1 CEMIP2	1.01e-05	177	72	5	2433924dcb085ebbe2545d476ebd7ee68e6092fb
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FAM72D VWF PIK3R3 ESAM EPAS1	1.03e-05	178	72	5	360d7a987f91d6d721487a921824057ec31a7332
ToppCell	390C-Endothelial_cells-Endothelial-E-\|390C / Donor, Lineage, Cell class and subclass (all cells)	VWF PIK3R3 ESAM PRKCE EPAS1	1.03e-05	178	72	5	804ac3725c1f88e2212172bfb9aa01d97a735621
ToppCell	367C-Endothelial_cells-Endothelial-B_(Artery)\|367C / Donor, Lineage, Cell class and subclass (all cells)	VWF ENPP2 PIK3R3 ESAM EPAS1	1.03e-05	178	72	5	e1e96a0e3ff718ebf676a982bc63e8ced6984059
ToppCell	367C-Endothelial_cells-Endothelial-B_(Artery)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	VWF ENPP2 PIK3R3 ESAM EPAS1	1.03e-05	178	72	5	363e8b23b3834692a8a79e5fdc7b43bd3a4dab5e
ToppCell	390C-Endothelial_cells-Endothelial-E\|390C / Donor, Lineage, Cell class and subclass (all cells)	VWF PIK3R3 ESAM PRKCE EPAS1	1.03e-05	178	72	5	ad6dc4a375664c919bd48c35c48a561fc5a7de8c
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF SLF1 ESAM EPAS1 CEMIP2	1.09e-05	180	72	5	baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF SLF1 ESAM EPAS1 CEMIP2	1.09e-05	180	72	5	2d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF SLF1 ESAM EPAS1 CEMIP2	1.09e-05	180	72	5	0f9b27054358c4737eed06c8ea01987cccc3cb55
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF PIK3R3 ESAM EPAS1 CEMIP2	1.12e-05	181	72	5	4d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCell	E12.5-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	THBS1 TINAG TRIM2 TMEM59L LAMC2	1.15e-05	182	72	5	204530444e35d4977a7239ac176f477e9e5c29ab
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF PIK3R3 ESAM EPAS1 CEMIP2	1.18e-05	183	72	5	3427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCell	E12.5-Epithelial-epithelial_progenitor_cell-epi_progenitor\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	THBS1 TINAG TRIM2 TMEM59L LAMC2	1.18e-05	183	72	5	031b4ffd95114dc10d2932c67d2cfef139b3fd2e
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF PIK3R3 ESAM EPAS1 CEMIP2	1.21e-05	184	72	5	087666ba949b129c53d7ace40f9e543e3875a7de
ToppCell	3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF ENPP2 PIK3R3 ESAM EPAS1	1.21e-05	184	72	5	842473fa415575441b595073a994b6d621169776
ToppCell	343B-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	VWF ESAM PRKCE EPAS1 CEMIP2	1.28e-05	186	72	5	dae6a98963c78bf7518ebab8dc02f173c3b0f7f7
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	KMT2C THBS1 MUC19 USH2A LRP1B	1.28e-05	186	72	5	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	343B-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	VWF ESAM PRKCE EPAS1 CEMIP2	1.28e-05	186	72	5	080e56113b89138277a2bd2eabddfa6cd1a18b61
ToppCell	COPD-Endothelial-VE_Arterial\|World / Disease state, Lineage and Cell class	VWF ENPP2 PIK3R3 ESAM EPAS1	1.31e-05	187	72	5	be42ee71d3412bb1f52593d8814de85c354a0efa
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF PIK3R3 ESAM EPAS1 CEMIP2	1.31e-05	187	72	5	6cf7be5401b81a4eeb30840fb3733d61a24af539
ToppCell	E12.5-Epithelial-epithelial_progenitor_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	THBS1 TINAG TRIM2 TMEM59L LAMC2	1.31e-05	187	72	5	ab6f4d387218b4651fdadbf269806c1ddc96a1d2
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D175\|Adult / Lineage, Cell type, age group and donor	VWF ESAM PRKCE EPAS1 CEMIP2	1.31e-05	187	72	5	f3548817f2fded5978137bb252cb628ac199e4f6
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF PIK3R3 ESAM EPAS1 CEMIP2	1.31e-05	187	72	5	63834420db930df91b62494c9d7aaa9a25bca530
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF PIK3R3 ESAM EPAS1 CEMIP2	1.31e-05	187	72	5	7170694a1b86fe8d84d96c880ffe57af09bdc026
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	EYS VWF MUC19 ESAM EPAS1	1.35e-05	188	72	5	366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCell	3'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF ENPP2 PIK3R3 ESAM EPAS1	1.35e-05	188	72	5	be3d287ca60ec9b42be1a8eb0a9b911c16cd8c3a
ToppCell	3'-Adult-Distal_Rectal-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF ENPP2 PIK3R3 ESAM EPAS1	1.38e-05	189	72	5	0c612ff5f882f2d8ec744a347780bbbe7cc471bd
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF PIK3R3 ESAM EPAS1 CEMIP2	1.38e-05	189	72	5	9da012fdfa9a8d488cab710a463a1d70e89f990c
ToppCell	3'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF ENPP2 PIK3R3 ESAM EPAS1	1.38e-05	189	72	5	bc8949bd4f425ed36e2c05e653c94cb1593c5bee
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF PIK3R3 ESAM EPAS1 CEMIP2	1.38e-05	189	72	5	1e1afa66b32ae752c0a42b02b80f10205464569c
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|kidney / Disease (COVID-19 only), tissue and cell type	VWF ENPP2 PIK3R3 ESAM EPAS1	1.42e-05	190	72	5	1519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF PIK3R3 ESAM EPAS1 CEMIP2	1.42e-05	190	72	5	d87b9e9ca863270a9c7f61674271a6440c97d1f4
ToppCell	3'-Child04-06-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF ENPP2 PIK3R3 ESAM EPAS1	1.42e-05	190	72	5	ec6b8e2852e1cce0217ff61243defe98b2351640
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF ENPP2 PIK3R3 ESAM EPAS1	1.45e-05	191	72	5	adb2e3efcad02889d8229325080da5e7830fd3ae
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF PIK3R3 ESAM EPAS1 CEMIP2	1.45e-05	191	72	5	3307dbccadb09c62b0e1c0235ec89bb294d748c3
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWF SLF1 ESAM PRKCE EPAS1	1.45e-05	191	72	5	a7b18bcf27c38ad2353c239ecb309c80f3ef3359
ToppCell	5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THBS1 VWF ENPP2 ESAM EPAS1	1.49e-05	192	72	5	eafead22bba48ac5ee568faa8946c444445c1034
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF PIK3R3 ESAM EPAS1 CEMIP2	1.49e-05	192	72	5	285a9d332a1e07b94f222d4b518dd56928b9e075
ToppCell	LPS-IL1RA+antiTNF-Endothelial\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWF SLF1 ESAM PRKCE EPAS1	1.49e-05	192	72	5	04f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCell	Control-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	VWF ENPP2 PIK3R3 LRP1B EPAS1	1.49e-05	192	72	5	7e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWF SLF1 ESAM PRKCE EPAS1	1.49e-05	192	72	5	c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	VWF PIK3R3 ESAM PRKCE EPAS1	1.53e-05	193	72	5	f582e939e3e08a8a3f71deec78c33715be8faa51
ToppCell	LPS-antiTNF-Endothelial-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWF SLF1 ESAM PRKCE EPAS1	1.53e-05	193	72	5	02f633b016ab19bfa65bfd0cf32f000549a62148
ToppCell	COPD-Endothelial-VE_Arterial\|COPD / Disease state, Lineage and Cell class	VWF ENPP2 PIK3R3 ESAM EPAS1	1.53e-05	193	72	5	1c701b6ab5f0f0239634adac94fa1c92bf3c36f4
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF ENPP2 PIK3R3 ESAM EPAS1	1.53e-05	193	72	5	1e6e2d786511cc40241197368f5df20c20b882f3
ToppCell	LPS_only-Endothelial-Endothelial-Gen_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWF SLF1 ENPP2 ESAM EPAS1	1.53e-05	193	72	5	af5108260783e69a7d67896c5bf64f862525926d
ToppCell	IPF-Endothelial-VE_Arterial\|IPF / Disease state, Lineage and Cell class	VWF ENPP2 PIK3R3 ESAM EPAS1	1.53e-05	193	72	5	bf83b1fe9d38408f30eee4eb634341c04ef82791
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)\|Adult / Lineage, Cell type, age group and donor	VWF ESAM PRKCE EPAS1 CEMIP2	1.53e-05	193	72	5	39c6c96a2a100b1b290a779d36cc6bc17245720b
ToppCell	LPS-antiTNF-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWF SLF1 ESAM PRKCE EPAS1	1.53e-05	193	72	5	5122b1ffba42de190061be34ecdc6176f84e56a3
ToppCell	Control-Endothelial-VE_Arterial\|World / Disease state, Lineage and Cell class	VWF ENPP2 PIK3R3 ESAM EPAS1	1.53e-05	193	72	5	52c0f2c7af57436f23e0c0e0c87086c47695e2c4
ToppCell	IPF-Endothelial-VE_Arterial\|World / Disease state, Lineage and Cell class	VWF ENPP2 PIK3R3 ESAM EPAS1	1.53e-05	193	72	5	70a9aadda83a97e06e9bc2d1327ce60dd3c58767
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	VWF PIK3R3 ESAM PRKCE EPAS1	1.53e-05	193	72	5	ad3f4fcc8e2816d696cbcde744dc16500e51ccac
ToppCell	(6)_Endothelial-B_(Artery)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	VWF ENPP2 PIK3R3 ESAM EPAS1	1.57e-05	194	72	5	0cf4e67d4024652794b5bfdd4a71a7d98900b4c8
ToppCell	LPS_only-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWF SLF1 ESAM PRKCE EPAS1	1.57e-05	194	72	5	58f069efdefa0366033764446b9d6ffd4a17807e
ToppCell	3'-Adult-LymphNode-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF ENPP2 OSBPL1A ESAM EPAS1	1.57e-05	194	72	5	622461e5f9c648252a2f6ec84e7565220a803132
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF FEZF1 ESAM EPAS1 CEMIP2	1.57e-05	194	72	5	e8102c8811333f04de7280b7d9b6b85cebb815ac
ToppCell	LPS_only-Endothelial-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWF SLF1 ESAM PRKCE EPAS1	1.57e-05	194	72	5	bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF FEZF1 ESAM EPAS1 CEMIP2	1.57e-05	194	72	5	4b0d63babb8a46ff45731d5f82b29ccaf6c9402d
ToppCell	Control-Endothelial-VE_Arterial\|Control / Disease state, Lineage and Cell class	VWF ENPP2 PIK3R3 ESAM EPAS1	1.61e-05	195	72	5	56c66a3655820961e1390b8f4bcc5618e8d0c5a8
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF ENPP2 PIK3R3 ESAM EPAS1	1.61e-05	195	72	5	83da75d210ae9c2a94018d70cb9e833b37004c4e
ToppCell	5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF ENPP2 PIK3R3 ESAM EPAS1	1.65e-05	196	72	5	c5fe470f11ee4962bcfb30cddfd8c078af5b1222
ToppCell	ASK428-Endothelial-Endothelium\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	THBS1 VWF ENPP2 PIK3R3 EPAS1	1.65e-05	196	72	5	b1a81eddb91fb462360692b7b0a3ba4a947eac40
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	VWF ENPP2 PIK3R3 ESAM EPAS1	1.65e-05	196	72	5	a20a56d8997d6db2a10046c8801c619a379de83c
ToppCell	IPF-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	PIK3R3 ESAM PRKCE EPAS1 CEMIP2	1.65e-05	196	72	5	8f0f72ead06abe02b575e443552eacc2151077ef
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF ENPP2 PIK3R3 ESAM EPAS1	1.69e-05	197	72	5	61b1b10a017cbeb17f8529fcae66cba77ee2f115
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF ENPP2 PIK3R3 ESAM EPAS1	1.69e-05	197	72	5	87eda06344498dc66cac292cf89746dc90b5cf67
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF ENPP2 PIK3R3 PRKCE EPAS1	1.69e-05	197	72	5	1ab86f5c05a3d8f352420e62277d5c79933063d8
ToppCell	(4)_Blood_vessel\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	VWF ENPP2 PIK3R3 ESAM EPAS1	1.69e-05	197	72	5	1b82979a41ef46c814c82527a585900586d71260
ToppCell	(4)_Endothelial_cells\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	VWF ENPP2 PIK3R3 ESAM EPAS1	1.69e-05	197	72	5	dd9abb43c23e7698433e455eacbf5b23b0a756c2
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF ENPP2 PIK3R3 ESAM EPAS1	1.69e-05	197	72	5	c29ed0e706999d4c2b93e6e3bf46c42aeceb4813
ToppCell	cellseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	VWF ENPP2 PIK3R3 ESAM EPAS1	1.69e-05	197	72	5	56afed433887cb2766eb30f22aec195148db33ab
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF ENPP2 PIK3R3 ESAM EPAS1	1.73e-05	198	72	5	1b9200e30f1d9b91bb0c6411c4f95208aedbe161
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	VWF ENPP2 PIK3R3 ESAM EPAS1	1.73e-05	198	72	5	5e781583908c4ee107d986904a646a7c6b8e3591
ToppCell	ASK452-Endothelial-Endothelium\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	VWF ENPP2 ESAM EPAS1 CEMIP2	1.73e-05	198	72	5	e282769f5fa1765bcce79a0ed9d761bf2e14b012
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VWF ENPP2 PIK3R3 ESAM EPAS1	1.73e-05	198	72	5	9e103228ac2cc86eec58bc6b8e142965228e8853
ToppCell	3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF ENPP2 PIK3R3 ESAM EPAS1	1.73e-05	198	72	5	5b86dc00acf8ac2ede008f5d79c09996485bf250
ToppCell	5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF ENPP2 PIK3R3 ESAM EPAS1	1.73e-05	198	72	5	8a55589b9244283e4b0b423a4a6d6202e8e0fec9
ToppCell	5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF ENPP2 PIK3R3 ESAM EPAS1	1.73e-05	198	72	5	d1f54ed3ef5e05ebda7da999e172d168dc6802cd
Drug	Protriptyline hydrochloride [1225-55-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A	TRIM2 TRPM2 LAMC2 ATP1A3 ZMYM6 ZFPL1 CEMIP2	2.43e-06	191	72	7	6498_UP
Drug	Thioridazine hydrochloride [130-61-0]; Down 200; 9.8uM; PC3; HG-U133A	THBS1 SURF2 FBXW4 FBXO11 SNX19 ZNF239 NMD3	2.70e-06	194	72	7	1905_DN
Drug	Arecoline hydrobromide [300-08-3]; Down 200; 17uM; HL60; HT_HG-U133A	EXOC5 DCTN5 JADE3 NSD2 PIK3R3 MLLT10 ZNF557	2.79e-06	195	72	7	1303_DN
Drug	Gly-His-Lys acetate salt; Up 200; 1uM; PC3; HT_HG-U133A	EXOC5 THBS1 NSD2 LAMC2 MLLT10 HERC4 NMD3	2.89e-06	196	72	7	6570_UP
Drug	rofecoxib; Down 200; 10uM; HL60; HG-U133A	NSD2 ZNF480 PRKCE FBXO11 MLLT10 SNX19 ZNF557	2.99e-06	197	72	7	371_DN
Drug	indomethacin, USP; Down 200; 100uM; SKMEL5; HG-U133A	RALGAPA1 THBS1 SURF2 TMEM59L LAMC2 MLLT10 PRDM14	2.99e-06	197	72	7	503_DN
Drug	17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A	PAPPA2 ZNF10 TRIM2 TRPM2 OSBPL1A HERC4	1.94e-05	175	72	6	5222_UP
Drug	Mepenzolate bromide [76-90-4]; Down 200; 9.6uM; PC3; HT_HG-U133A	RALGAPA1 ZNF611 FBXO11 LAMC2 MSH3 HERC4	3.00e-05	189	72	6	4304_DN
Drug	CP-944629 [668990-94-1]; Down 200; 10uM; PC3; HT_HG-U133A	EXOC5 THBS1 ZNF480 MLLT10 HERC4 NMD3	3.18e-05	191	72	6	7549_DN
Drug	Glycopyrrolate [596-51-0]; Up 200; 10uM; MCF7; HT_HG-U133A	THBS1 PIK3R3 PRKCE LAMC2 MUC5AC ZFPL1	3.47e-05	194	72	6	4709_UP
Drug	Benzocaine [94-09-7]; Down 200; 24.2uM; PC3; HT_HG-U133A	NSD2 GLI2 FBXO11 LAMC2 MLLT10 CEMIP2	3.57e-05	195	72	6	4224_DN
Drug	Articaine hydrochloride [23964-57-0]; Up 200; 12.4uM; MCF7; HT_HG-U133A	TRIM2 NSD2 TRPM2 MUC5AC EPAS1 ZMYM6	3.89e-05	198	72	6	6517_UP
Drug	cobalt(II) chloride hexahydrate; Down 200; 100uM; MCF7; HG-U133A	TRIM2 SURF2 TRPM2 PRKCE PRDM14 ZFPL1	3.89e-05	198	72	6	383_DN
Drug	Conessine [546-06-5]; Up 200; 11.2uM; MCF7; HT_HG-U133A	RALGAPA1 TRIM2 LAMC2 MUC5AC HERC4 ZFPL1	4.00e-05	199	72	6	4777_UP
Drug	Imipramine hydrochloride [113-52-0]; Up 200; 12.6uM; MCF7; HT_HG-U133A	ZNF10 TRIM2 FBXO11 JADE1 MUC5AC ZFPL1	4.11e-05	200	72	6	1685_UP
Drug	Lysophosphatidylcholines	ENPP2 PRKCE LAMC2	4.47e-05	22	72	3	ctd:D008244
Disease	lung non-small cell carcinoma (is_implicated_in)	KMT2C NSD2 FBXO11 MSH3 LRP1B PRDM14 EPAS1	3.74e-08	139	69	7	DOID:3908 (is_implicated_in)
Disease	interstitial lung disease	IVD MUC5AC EPAS1	5.27e-04	67	69	3	EFO_0004244
Disease	migraine disorder, endometriosis	EYS MLLT10 LRP1B	6.77e-04	73	69	3	EFO_0001065, MONDO_0005277
Disease	Muscle hypotonia	RALGAPA1 NSD2	7.16e-04	17	69	2	C0026827
Disease	Sjogren's syndrome (implicated_via_orthology)	THBS1 MUC19	7.16e-04	17	69	2	DOID:12894 (implicated_via_orthology)
Disease	venous thromboembolism	PAPPA2 NUGGC VWF STXBP5 FAM72A PRKCE	7.27e-04	460	69	6	EFO_0004286
Disease	factor VIII measurement, Ischemic stroke	VWF STXBP5	8.98e-04	19	69	2	EFO_0004630, HP_0002140
Disease	alpha-tocopherol measurement	PRKCE USH2A	9.96e-04	20	69	2	EFO_0007898
Disease	venous thromboembolism, tissue plasminogen activator measurement	VWF STXBP5	1.32e-03	23	69	2	EFO_0004286, EFO_0004791
Disease	Sjogren's syndrome (is_marker_for)	MUC19 MUC5AC	1.44e-03	24	69	2	DOID:12894 (is_marker_for)
Disease	cerebral amyloid deposition measurement	CCDC60 MUC19 PRKCE	1.45e-03	95	69	3	EFO_0007707
Disease	factor VIII measurement, von Willebrand factor measurement	VWF STXBP5	1.82e-03	27	69	2	EFO_0004629, EFO_0004630
Disease	retinitis pigmentosa (implicated_via_orthology)	EYS USH2A	1.82e-03	27	69	2	DOID:10584 (implicated_via_orthology)
Disease	pulmonary hypertension (is_implicated_in)	VWF EPAS1	2.25e-03	30	69	2	DOID:6432 (is_implicated_in)
Disease	Ischemic stroke, von Willebrand factor measurement	VWF STXBP5	2.25e-03	30	69	2	EFO_0004629, HP_0002140

Protein segments in the cluster

Peptide	Gene	Start	Entry
ACVEAYVKEAEQQAC	TMEM59L	106	Q9UK28
IKVYQQHCGGENLCV	ERICH3	311	Q5RHP9
KVLHCTGQVKVYNNC	EPAS1	191	Q99814
CHSCPKAIEVVVNAY	ASB4	331	Q9Y574
NCDINIHYKSGVCNT	CCDC60	371	Q8IWA6
NTCHFEDEKICGYTQ	MDGA1	751	Q8NFP4
QQHKDAVLCVECGYK	MSH3	241	P20585
YINHSCAPNCVAEVV	KMT2C	4846	Q8NEZ4
HQCINVEGSYKCVCD	LRP1B	3856	Q9NZR2
CVVNVDYCLGNHSIS	EYS	601	Q5T1H1
DIACLKCGNIVGYHV	FAM72D	71	Q6L9T8
LVIINEYGSCTCHQQ	LRRTM1	501	Q86UE6
KQGYQCQVCTCVVHK	PRKCE	196	Q02156
AGVQCTCQHYTVREE	LBHD1	246	Q9BQE6
CEDGIQHCNKIIGTY	MUC19	641	Q7Z5P9
SQKIVYICCGEDHTA	HERC4	241	Q5GLZ8
VVTQCGKFYHEACVK	NSD2	731	O96028
CKQEAEVVIYETNCH	GLI2	426	P10070
CTAVAAYAQACHEVG	MUC5AC	1136	P98088
KAEACVCTYNGQRFH	MUC5AC	1271	P98088
ICGYSHQNSQCKAVT	MS4A5	146	Q9H3V2
DIACLKCGNIVGYHV	FAM72A	71	Q5TYM5
QYVYNVAKACDEGHC	IVD	341	P26440
IYRQGCKHLTQAVCT	OSBPL1A	276	Q9BXW6
YCAGHIIKNCICTNV	OR56A5	171	P0C7T3
CLQDNHDVGTICKYE	PAPPA2	1541	Q9BXP8
YACSVVADGEVKHCV	PIK3R3	391	Q92569
SHCVDVYIKQCQEGA	EXOC5	226	O00471
KHCNISDCENVGLYI	FBXO11	401	Q86XK2
HSYCSSQGCERVKIQ	CEMIP2	1141	Q9UHN6
AAQIGSYVHVGKNCV	DCTN5	101	Q9BTE1
VYVCKAHNEVGTAQC	ESAM	221	Q96AP7
VKYSAHEQEVNCVDC	FBXW4	196	P57775
VCRKYNTDCVQGLTH	ATP1A3	41	P13637
CIHNTAGIYCDQCKA	LAMC2	541	Q13753
GACEKTVYHAEEIQC	CSRP3	11	P50461
QVCVNTVGSYECQCH	SCUBE2	416	Q9NQ36
CTNYQVVCKGESHWV	ENPP2	131	Q13822
DKCNVCVHQACYGIL	JADE3	221	Q92613
DIACLKCGNIVGYHV	FAM72B	71	Q86X60
TVFHQSCQAVVKKGC	PLEKHM1	1026	Q9Y4G2
HVYVCAVCQNVFCVD	GTF2H2C;	356	Q6P1K8
QVEVCTIYACVKSNG	USH2A	3086	O75445
QVSSGCCVQYEAKIH	NUGGC	141	Q68CJ6
AVQCQGHIFYESCKE	PRDM14	341	Q9GZV8
TCEVCGKVFNAHYNL	FEZF1	261	A0PJY2
CQKQGVEYVPACLVH	SURF2	116	Q15527
CNICVHQACYGILKV	JADE1	226	Q6IE81
CYCQHDSGAAVIQLQ	STXBP5	91	Q5T5C0
GCSVAVHQACYGIVQ	MLLT10	46	P55197
YSKCQDCIHRLGQVV	CLCN1	96	P35523
ENLVCVANATYHCKK	THBS1	701	P07996
CKVCQAYLGQLEHED	TTLL8	271	A6PVC2
KVLHGCVYGAQCFSN	RALGAPA1	1431	Q6GYQ0
SEVEVDIHYCQGKCA	VWF	2741	P04275
HVYVCAVCQNVFCVD	GTF2H2	356	Q13888
LSDAGKVVCQCGYTH	TRPM2	81	O94759
KVVCQCGYTHEQHLE	TRPM2	86	O94759
LCGCHLQSYIQAKEA	SNX19	161	Q92543
HEACNYGNTVCVQEI	SLF1	846	Q9BQI6
AQVKCYRCGEIGHVA	ZCCHC13	126	Q8WW36
CTVTYYCGVVHQKAD	ZMYND12	31	Q9H0C1
HVGEETYKCNQCGII	ZNF10	511	P21506
YKCNECGKVFIQNSH	ZNF480	371	Q8WV37
VKYQNVVHGLCSDAC	ZMYM6	206	O95789
HTQEQLYKCEQCGKA	ZNF57	386	Q68EA5
CDVCGKLFNHEQYLA	ZNF611	261	Q8N823
GAECYCGHKIQATNV	WSCD2	176	Q2TBF2
HTAEKQYECSQCGKN	ZNF239	201	Q16600
HYEEGSVIKENCNSC	TINAG	126	Q9UJW2
NGHIIVVDNKACCVF	TRIM2	586	Q9C040
KRVHTGEGHYVCNQC	ZNF557	276	Q8N988
HCLVANHAKCIVQSY	ZFPL1	26	O95159
HSGQKSYVCIECGQA	ZNF175	441	Q9Y473
VVDYVVQSQMCGDCH	NMD3	131	Q96D46