Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNHD1 KIF13B MYH6 MYH8 KIFC2 DNAH1 MYO15A	2.27e-05	118	143	7	GO:0003774
HumanPheno	Abnormal lower limb bone morphology	MYH8 ATR OBSL1 DAG1 SMPD4 ZSWIM6 CUL7 WNK1 BBS9 PALB2 BAP1 ALMS1 RTL1 KCNN3 FGFR1 LTBP3 TAF4 SPEN PLOD2 WNK3 HTT	5.24e-06	866	46	21	HP:0040069
HumanPheno	Positional foot deformity	MYH8 ATR FA2H ZSWIM6 BBS9 BAP1 TGFBR1 SNIP1 RTL1 IGHMBP2 FGFR1 LTBP3 SPEN PLOD2 WNK3 HTT	2.83e-05	587	46	16	HP:0005656
Domain	Cul7	CUL9 CUL7	1.69e-04	3	141	2	PF11515
Domain	CPH_domain	CUL9 CUL7	1.69e-04	3	141	2	IPR021097
Domain	F-box-like	SKP2 FBH1 FBXO8 FBXO42	3.34e-04	44	141	4	PF12937
Domain	HEAT	ATR HEATR1 IPO4 HTT	4.68e-04	48	141	4	PF02985
Domain	TAFH	RUNX1T1 TAF4	5.58e-04	5	141	2	SM00549
Domain	TAFH_NHR1	RUNX1T1 TAF4	5.58e-04	5	141	2	IPR003894
Domain	TAFH	RUNX1T1 TAF4	5.58e-04	5	141	2	PS51119
Domain	TAFH	RUNX1T1 TAF4	5.58e-04	5	141	2	PF07531
Domain	SMAD_FHA_domain	KIF13B IRF4 SNIP1 MCRS1	6.36e-04	52	141	4	IPR008984
Domain	OSR1_C	WNK1 WNK3	8.32e-04	6	141	2	PF12202
Domain	Kinase_OSR1/WNK_CCT	WNK1 WNK3	8.32e-04	6	141	2	IPR024678
Domain	HEAT	ATR HEATR1 IPO4 HTT	9.63e-04	58	141	4	IPR000357
Domain	APC_su10/DOC_dom	CUL9 CUL7	1.16e-03	7	141	2	IPR004939
Domain	DOC	CUL9 CUL7	1.16e-03	7	141	2	PS51284
Domain	ANAPC10	CUL9 CUL7	1.16e-03	7	141	2	PF03256
Domain	APC10	CUL9 CUL7	1.16e-03	7	141	2	SM01337
Domain	FHA	KIF13B SNIP1 MCRS1	1.20e-03	28	141	3	SM00240
Domain	Cullin_neddylation_domain	CUL9 CUL7	1.54e-03	8	141	2	IPR019559
Domain	Cullin_Nedd8	CUL9 CUL7	1.54e-03	8	141	2	PF10557
Domain	Cullin_Nedd8	CUL9 CUL7	1.54e-03	8	141	2	SM00884
Domain	FHA_DOMAIN	KIF13B SNIP1 MCRS1	1.62e-03	31	141	3	PS50006
Domain	FHA	KIF13B SNIP1 MCRS1	1.62e-03	31	141	3	PF00498
Domain	F-box	SKP2 FBH1 FBXO8 FBXO42	1.65e-03	67	141	4	PF00646
Domain	HEAT_REPEAT	ATR HEATR1 IPO4 HTT	1.94e-03	70	141	4	PS50077
Domain	Cullin_homology	CUL9 CUL7	1.97e-03	9	141	2	IPR016158
Domain	FBOX	SKP2 FBH1 FBXO8 FBXO42	2.15e-03	72	141	4	PS50181
Domain	Cullin	CUL9 CUL7	2.45e-03	10	141	2	PF00888
Domain	CULLIN_2	CUL9 CUL7	2.45e-03	10	141	2	PS50069
Domain	Ank_3	ANKRD23 ANKRD27	2.45e-03	10	141	2	PF13606
Domain	Cullin_N	CUL9 CUL7	2.45e-03	10	141	2	IPR001373
Domain	CULLIN_1	CUL9 CUL7	2.45e-03	10	141	2	PS01256
Domain	F-box_dom	SKP2 FBH1 FBXO8 FBXO42	2.50e-03	75	141	4	IPR001810
Domain	-	KIF13B SNIP1 MCRS1	2.51e-03	36	141	3	2.60.200.20
Domain	FHA_dom	KIF13B SNIP1 MCRS1	2.51e-03	36	141	3	IPR000253
Domain	SH3_9	ARHGAP32 RUSC1 SH3D19 ITSN2	2.88e-03	78	141	4	PF14604
Domain	Myosin_head_motor_dom	MYH6 MYH8 MYO15A	2.93e-03	38	141	3	IPR001609
Domain	MYOSIN_MOTOR	MYH6 MYH8 MYO15A	2.93e-03	38	141	3	PS51456
Domain	Myosin_head	MYH6 MYH8 MYO15A	2.93e-03	38	141	3	PF00063
Domain	MYSc	MYH6 MYH8 MYO15A	2.93e-03	38	141	3	SM00242
Domain	Oxysterol-bd_CS	OSBPL7 OSBPL10	3.55e-03	12	141	2	IPR018494
Domain	Oxysterol_BP	OSBPL7 OSBPL10	3.55e-03	12	141	2	PF01237
Domain	Oxysterol-bd	OSBPL7 OSBPL10	3.55e-03	12	141	2	IPR000648
Domain	OSBP	OSBPL7 OSBPL10	3.55e-03	12	141	2	PS01013
Domain	-	LPCAT4 CBLB TBC1D9 TBC1D8 PLCD3 NKD1 ITSN2	3.71e-03	261	141	7	1.10.238.10
Domain	Dynein_HC_stalk	DNHD1 DNAH1	4.85e-03	14	141	2	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DNAH1	4.85e-03	14	141	2	IPR013602
Domain	DHC_N2	DNHD1 DNAH1	4.85e-03	14	141	2	PF08393
Domain	MT	DNHD1 DNAH1	4.85e-03	14	141	2	PF12777
Domain	-	DAB2IP PLCD3 ESYT2 PIK3CG ITSN2	5.33e-03	148	141	5	2.60.40.150
Domain	DHC_fam	DNHD1 DNAH1	5.57e-03	15	141	2	IPR026983
Domain	Dynein_heavy	DNHD1 DNAH1	5.57e-03	15	141	2	PF03028
Domain	PI3/4_kinase_CS	ATR PIK3CG	5.57e-03	15	141	2	IPR018936
Domain	Myosin_N	MYH6 MYH8	5.57e-03	15	141	2	PF02736
Domain	Dynein_heavy_dom	DNHD1 DNAH1	5.57e-03	15	141	2	IPR004273
Domain	Myosin_N	MYH6 MYH8	5.57e-03	15	141	2	IPR004009
Domain	SH3	ARHGAP32 RUSC1 ARHGAP4 SH3D19 ITSN2 MYO15A	6.01e-03	216	141	6	SM00326
Domain	SH3	ARHGAP32 RUSC1 ARHGAP4 SH3D19 ITSN2 MYO15A	6.01e-03	216	141	6	PS50002
Domain	TBC	TBC1D9 TBC1D8 TBC1D4	6.02e-03	49	141	3	SM00164
Domain	EF-hand-dom_pair	LPCAT4 CBLB TBC1D9 TBC1D8 PLCD3 NKD1 ITSN2	6.19e-03	287	141	7	IPR011992
Domain	GRAM	TBC1D9 TBC1D8	6.34e-03	16	141	2	SM00568
Domain	P4Hc	P3H3 PLOD2	6.34e-03	16	141	2	SM00702
Domain	-	ATR PIK3CG	6.34e-03	16	141	2	1.10.1070.11
Domain	PI3Kc	ATR PIK3CG	6.34e-03	16	141	2	SM00146
Domain	Pro_4_hyd_alph	P3H3 PLOD2	6.34e-03	16	141	2	IPR006620
Domain	SH3_domain	ARHGAP32 RUSC1 ARHGAP4 SH3D19 ITSN2 MYO15A	6.55e-03	220	141	6	IPR001452
Domain	-	ATR CUL9 HEATR1 CUL7 IPO4 HTT	6.84e-03	222	141	6	1.25.10.10
Domain	FBOX	SKP2 FBH1 FBXO42	7.11e-03	52	141	3	SM00256
Domain	HEAT_type_2	ATR IPO4	7.15e-03	17	141	2	IPR021133
Domain	RabGAP-TBC	TBC1D9 TBC1D8 TBC1D4	7.49e-03	53	141	3	PF00566
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DAB2IP EPPK1 SZT2 MFHAS1 CUL9 GBX2 WNK1 KIFC2 TBC1D9 PHC2 BAP1 PLCD3 SLC12A4 NFKB2 FGFR1 LTBP3 SPEN CRAMP1 MED13 SOWAHB HTT	7.23e-09	1105	145	21	35748872
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	OBSL1 CUL9 SMPD4 HEATR1 CUL7 RUNX1T1 SKP2 BAP1 ZBTB37 ESYT2 KANSL2 TBC1D4 NFKB2 FBXO42 MCRS1 SPEN PLOD2	1.20e-07	857	145	17	25609649
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	KIF13B RAE1 OBSL1 CUL9 CUL7 IPO4 WNK1 TBC1D8 TBC1D4 ALMS1 NFKB2 FBXO42 SPEN ZNF574	1.92e-07	588	145	14	38580884
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	DAB2IP ARHGAP32 MAP4K3 DAG1 CBLB LRCH3 FAM171A1 RFTN1 ESYT2 WDR20 ITSN2 OSBPL10	2.25e-07	421	145	12	36976175
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	MED8 WHAMM ERMP1 HEATR1 IPO4 ANKZF1 PHC2 LRCH3 NGDN PLCD3 SNIP1 RFTN1 ESYT2 IGHMBP2 WDR20 ITSN2 MCRS1 TAF4 SPEN MED13 ZNF574	1.13e-06	1497	145	21	31527615
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	ARHGAP32 CUL9 CUL7 TBC1D4 ALMS1 ITSN2 MED13	1.30e-06	130	145	7	12421765
Pubmed	Tumor-associated antigen Prame targets tumor suppressor p14/ARF for degradation as the receptor protein of CRL2Prame complex.	CUL9 CUL7 SKP2 FBH1 FBXO42	1.74e-06	48	145	5	33504946
Pubmed	Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.	ARHGAP32 CBLB WNK1 ALMS1 SH3D19	5.34e-06	60	145	5	34761192
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KIF13B ARHGAP32 CUL7 WNK1 TBC1D9 PLCD3 RFTN1 KRBA1 FAT2 ALMS1 FBXO42	7.64e-06	493	145	11	15368895
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KIF13B MYH6 MYH8 LIMA1 HYOU1 MED8 LPCAT4 HEATR1 PALB2 TASOR2 NGDN RFTN1 MFNG SLC12A4 ITSN2 FGFR1 TAF4 SPEN MED13	9.40e-06	1442	145	19	35575683
Pubmed	Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain.	WNK1 SLC12A4 WNK3	1.52e-05	12	145	3	27782176
Pubmed	Antigen-specific splenic CD4+ and CD8+ regulatory T cells generated via the eye, suppress experimental autoimmune encephalomyelitis either at the priming or at the effector phase.	CBLB MOG	1.73e-05	2	145	2	21273399
Pubmed	Natural history of facial and skeletal features from neonatal period to adulthood in a 3M syndrome cohort with biallelic CUL7 or OBSL1 variants.	OBSL1 CUL7	1.73e-05	2	145	2	34597859
Pubmed	Stabilization of MCRS1 by BAP1 prevents chromosome instability in renal cell carcinoma.	BAP1 MCRS1	1.73e-05	2	145	2	26300492
Pubmed	Regulation of ATR-dependent pathways by the FHA domain containing protein SNIP1.	ATR SNIP1	1.73e-05	2	145	2	17260016
Pubmed	Further expanding the mutational spectrum and investigation of genotype-phenotype correlation in 3M syndrome.	OBSL1 CUL7	1.73e-05	2	145	2	30980518
Pubmed	Regulation of Na+-K+-Cl- cotransporter type 2 by the with no lysine kinase-dependent signaling pathway.	WNK1 WNK3	1.73e-05	2	145	2	30917032
Pubmed	Analysis of an ethylnitrosourea-generated mouse mutation defines a cell intrinsic role of nuclear factor kappaB2 in regulating circulating B cell numbers.	TGFBR1 NFKB2	1.73e-05	2	145	2	12391023
Pubmed	The role of homeostatic regulation between tumor suppressor DAB2IP and oncogenic Skp2 in prostate cancer growth.	DAB2IP SKP2	1.73e-05	2	145	2	25115390
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	RAE1 P3H3 LPCAT4 OBSL1 CUL9 BCL11A CUL7 SNIP1 ARHGAP4 AGO3 ALMS1 WDR20 MCRS1 SIGLEC1 TAF4 ZNF574	1.82e-05	1116	145	16	31753913
Pubmed	FBXW7 modulates cellular stress response and metastatic potential through HSF1 post-translational modification.	RAE1 MED8 IPO4 NFKB2 MED13	1.94e-05	78	145	5	25720964
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	LIMA1 ATR PALB2 TBC1D9 PHC2 BAP1 ESYT2 KANSL2 TBC1D4 USP42 TJAP1 SPEN MED13	2.32e-05	774	145	13	15302935
Pubmed	14-3-3 proteins sequester a pool of soluble TRIM32 ubiquitin ligase to repress autoubiquitylation and cytoplasmic body formation.	RAE1 WNK1 TBC1D4 WDR20	2.87e-05	42	145	4	23444366
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	MYH8 SZT2 C1orf43 HEATR1 ZSWIM6 WNK1 BAP1 TGFBR1 SLC12A4 FBXO42 WDR20 TAF4 CRAMP1 MED13 SOWAHB HTT ZNF574	4.09e-05	1327	145	17	32694731
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	EPHX1 ATRN ZNF142 C1orf43 LPCAT4 DAG1 SMPD4 HEATR1 SNIP1 ESYT2 TBC1D4 NKD1 USP42 PEDS1 IL17RA ZNF574	4.49e-05	1203	145	16	29180619
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	BCL11A CUL7 SKP2 ANKRD27 PHC2 BAP1 KANSL2 FBH1 FBXO42 MCRS1	4.64e-05	495	145	10	27705803
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	AKAP6 DAB2IP OBSL1 WNK1 BAP1 ESYT2 ALMS1	4.68e-05	225	145	7	12168954
Pubmed	VEGF induces Tie2 shedding via a phosphoinositide 3-kinase/Akt dependent pathway to modulate Tie2 signaling.	TEK PIK3CG	5.16e-05	3	145	2	17901375
Pubmed	Manic fringe promotes a claudin-low breast cancer phenotype through notch-mediated PIK3CG induction.	MFNG PIK3CG	5.16e-05	3	145	2	25808869
Pubmed	Dimerization of CUL7 and PARC is not required for all CUL7 functions and mouse development.	CUL9 CUL7	5.16e-05	3	145	2	15964813
Pubmed	A rare cause of syndromic short stature: 3M syndrome in three families.	OBSL1 CUL7	5.16e-05	3	145	2	33258289
Pubmed	Complete inhibition of goiter in mice requires combined gene therapy modification of angiopoietin, vascular endothelial growth factor, and fibroblast growth factor signaling.	TEK FGFR1	5.16e-05	3	145	2	15817662
Pubmed	The conserved CPH domains of Cul7 and PARC are protein-protein interaction modules that bind the tetramerization domain of p53.	CUL9 CUL7	5.16e-05	3	145	2	17298945
Pubmed	Three M Syndrome	OBSL1 CUL7	5.16e-05	3	145	2	20301654
Pubmed	Coupling of Homologous Recombination and the Checkpoint by ATR.	ATR PALB2	5.16e-05	3	145	2	28089683
Pubmed	A novel p53-binding domain in CUL7.	CUL9 CUL7	5.16e-05	3	145	2	16875676
Pubmed	Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease.	TAF4 HTT	5.16e-05	3	145	2	11988536
Pubmed	Expression of a mutant p193/CUL7 molecule confers resistance to MG132- and etoposide-induced apoptosis independent of p53 or Parc binding.	CUL9 CUL7	5.16e-05	3	145	2	17229476
Pubmed	The genetics of 3-M syndrome: unravelling a potential new regulatory growth pathway.	OBSL1 CUL7	5.16e-05	3	145	2	22156540
Pubmed	Exome sequencing identifies CCDC8 mutations in 3-M syndrome, suggesting that CCDC8 contributes in a pathway with CUL7 and OBSL1 to control human growth.	OBSL1 CUL7	5.16e-05	3	145	2	21737058
Pubmed	Basic fibroblast growth factor in the bone microenvironment enhances cell motility and invasion of Ewing's sarcoma family of tumours by activating the FGFR1-PI3K-Rac1 pathway.	PIK3CG FGFR1	5.16e-05	3	145	2	20606682
Pubmed	Mutations in CUL7, OBSL1 and CCDC8 in 3-M syndrome lead to disordered growth factor signalling.	OBSL1 CUL7	5.16e-05	3	145	2	23018678
Pubmed	Genetic ablation of PI3Kγ results in defective IL-17RA signalling in T lymphocytes and increased IL-17 levels.	PIK3CG IL17RA	5.16e-05	3	145	2	22930133
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DAB2IP PEG3 OBSL1 CUL9 BCL11A ZSWIM6 ITSN2 ASB1 SPEN	5.63e-05	407	145	9	12693553
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	KIF13B ARHGAP32 LIMA1 HIPK4 WNK1 ANKRD27 FAM171A1 ESYT2 TBC1D4 ALMS1 SH3D19 OSBPL10 WNK3	6.89e-05	861	145	13	36931259
Pubmed	Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures.	HIPK4 ZSWIM6 TBC1D8 HTT	7.24e-05	53	145	4	36265442
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	AKAP6 MAP4K3 DAG1 CUL9 CUL7 KIFC2 RPUSD2 SPEN	7.63e-05	329	145	8	17474147
Pubmed	Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study.	DAB2IP KIF13B ZNF213 ALMS1	9.00e-05	56	145	4	23934736
Pubmed	Characterization of the zinc-induced Shank3 interactome of mouse synaptosome.	HYOU1 TASOR2 RFTN1 MYO15A MOG	9.69e-05	109	145	5	29111324
Pubmed	Protein kinase WNK1 promotes cell surface expression of glucose transporter GLUT1 by regulating a Tre-2/USP6-BUB2-Cdc16 domain family member 4 (TBC1D4)-Rab8A complex.	WNK1 TBC1D4	1.03e-04	4	145	2	20937822
Pubmed	WNK kinases, a novel protein kinase subfamily in multi-cellular organisms.	WNK1 WNK3	1.03e-04	4	145	2	11571656
Pubmed	Human hypertension caused by mutations in WNK kinases.	WNK1 WNK3	1.03e-04	4	145	2	11498583
Pubmed	ETO, but not leukemogenic fusion protein AML1/ETO, augments RBP-Jkappa/SHARP-mediated repression of notch target genes.	RUNX1T1 SPEN	1.03e-04	4	145	2	18332109
Pubmed	SLC26A9 is a Cl(-) channel regulated by the WNK kinases.	WNK1 WNK3	1.03e-04	4	145	2	17673510
Pubmed	Direct role for the replication protein treslin (Ticrr) in the ATR kinase-mediated checkpoint response.	TICRR ATR	1.03e-04	4	145	2	23696651
Pubmed	Axon morphogenesis and maintenance require an evolutionary conserved safeguard function of Wnk kinases antagonizing Sarm and Axed.	WNK1 WNK3	1.03e-04	4	145	2	34384519
Pubmed	An integrated cell purification and genomics strategy reveals multiple regulators of pancreas development.	BCL11A RUNX1T1	1.03e-04	4	145	2	25330008
Pubmed	The 3M complex maintains microtubule and genome integrity.	OBSL1 CUL7	1.03e-04	4	145	2	24793695
Pubmed	Extended Synaptotagmin Interaction with the Fibroblast Growth Factor Receptor Depends on Receptor Conformation, Not Catalytic Activity.	ESYT2 FGFR1	1.03e-04	4	145	2	25922075
Pubmed	WNK1 phosphorylation sites in TBC1D1 and TBC1D4 modulate cell surface expression of GLUT1.	WNK1 TBC1D4	1.03e-04	4	145	2	31816312
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	TICRR RAE1 ATR FA2H HEATR1 PALB2 PHC2 BAP1 NGDN SNIP1 ESYT2 KANSL2 USP42 MCRS1 TAF4 SPEN	1.05e-04	1294	145	16	30804502
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	LIMA1 RAE1 CUL7 WNK1 SKP2 LRCH3 TBC1D4 ALMS1 NYNRIN	1.13e-04	446	145	9	24255178
Pubmed	Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D.	OBSL1 KANSL2 FBXO42	1.18e-04	23	145	3	31748650
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	DAB2IP BCL11A TBC1D9 PHC2 TASOR2 KANSL2 CACTIN-AS1 TJAP1 MCRS1 LTBP3	1.28e-04	560	145	10	21653829
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	C1orf43 RUSC1 IPO4 KANSL2 FBH1 SLC12A4 WDR20 OSBPL7 TJAP1 ASB1 FGFR1 LTBP3 PLOD2	1.40e-04	925	145	13	28986522
Pubmed	Large-scale concatenation cDNA sequencing.	LPCAT4 OBSL1 SMPD4 DBP RUNX1T1 KIFC2 TBC1D9 IGHMBP2 ITSN2 ASB1	1.44e-04	568	145	10	9110174
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	DAB2IP KIF13B ARHGAP32 C1orf43 DAG1 SMPD4 ESYT2 SLC12A4 WDR20 OSBPL10	1.46e-04	569	145	10	30639242
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	RAE1 ATR OBSL1 WNK1 RNF126 AGO3 NYNRIN PLOD2 WNK3	1.47e-04	462	145	9	31138677
Pubmed	Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation.	OBSL1 ZSWIM6 SKP2 PLCD3 FBH1	1.52e-04	120	145	5	27565346
Pubmed	A "double adaptor" method for improved shotgun library construction.	LPCAT4 OBSL1 SMPD4 DBP RUNX1T1 KIFC2 TBC1D9 IGHMBP2 ITSN2 ASB1	1.56e-04	574	145	10	8619474
Pubmed	Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution.	CUL9 DGLUCY AIFM3 SIGLEC1	1.71e-04	66	145	4	15790807
Pubmed	Mutant p53 perturbs DNA replication checkpoint control through TopBP1 and Treslin.	TICRR ATR	1.71e-04	5	145	2	28439015
Pubmed	Structural and biochemical characterization of the KLHL3-WNK kinase interaction important in blood pressure regulation.	WNK1 WNK3	1.71e-04	5	145	2	24641320
Pubmed	PARC and CUL7 form atypical cullin RING ligase complexes.	CUL9 CUL7	1.71e-04	5	145	2	17332328
Pubmed	Bikunin down-regulates heterodimerization between CD44 and growth factor receptors and subsequently suppresses agonist-mediated signaling.	TGFBR1 FGFR1	1.71e-04	5	145	2	15597342
Pubmed	Human claspin is required for replication checkpoint control.	ATR ITSN2	1.71e-04	5	145	2	12766152
Pubmed	DAB2IP coordinates both PI3K-Akt and ASK1 pathways for cell survival and apoptosis.	DAB2IP PIK3CG	1.71e-04	5	145	2	19903888
Pubmed	CUL9 mediates the functions of the 3M complex and ubiquitylates survivin to maintain genome integrity.	CUL9 CUL7	1.71e-04	5	145	2	24793696
Pubmed	Macrophage TGF-β signaling is critical for wound healing with heterotopic ossification after trauma.	TGFBR1 SIGLEC1	1.71e-04	5	145	2	36099022
Pubmed	WNK kinases sense molecular crowding and rescue cell volume via phase separation.	WNK1 WNK3	1.71e-04	5	145	2	36318922
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	AKAP6 DAB2IP PRRG1 KIF13B TICRR HYOU1 MAP4K3 FA2H PEG3 DAG1 HEATR1 WNK1 KIFC2 TGFBR1	1.86e-04	1084	145	14	11544199
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	HYOU1 RAE1 ATR P3H3 TBC1D9 PLOD2 HTT	2.03e-04	285	145	7	32838362
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	RUSC1 SMPD4 ANKRD27 WDR20 ITSN2 TJAP1 HTT	2.03e-04	285	145	7	34369648
Pubmed	Ankyrin repeats of ANKRA2 recognize a PxLPxL motif on the 3M syndrome protein CCDC8.	OBSL1 CUL7 HTT	2.15e-04	28	145	3	25752541
Pubmed	A genomic atlas of mouse hypothalamic development.	THSD4 ZSWIM6 TGFBR1 MFNG FGFR1 LTBP3	2.30e-04	205	145	6	20436479
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	DNHD1 EPPK1 SZT2 MED8 TBC1D4 SPEN	2.48e-04	208	145	6	33230847
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	ARHGAP32 OBSL1 CUL9 CUL7 CBLB TASOR2 LRCH3 DNAH1 AGO3	2.49e-04	496	145	9	31343991
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	TBC1D8 ESYT2 TBC1D4 ALMS1 NFKB2 FBXO42	2.55e-04	209	145	6	36779422
Pubmed	Opposing functions of circadian protein DBP and atypical E2F family E2F8 in anti-tumor Th9 cell differentiation.	DBP TGFBR1	2.56e-04	6	145	2	36241625
Pubmed	A small family of sushi-class retrotransposon-derived genes in mammals and their relation to genomic imprinting.	RTL1 NYNRIN	2.56e-04	6	145	2	16155747
Pubmed	Cooperation of TLR12 and TLR11 in the IRF8-dependent IL-12 response to Toxoplasma gondii profilin.	IRF4 NFKB2	2.56e-04	6	145	2	24078692
Pubmed	SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes.	SKP2 SNIP1	2.56e-04	6	145	2	17157259
Pubmed	Human transcription factor protein interaction networks.	ARHGAP32 LIMA1 MED8 CUL9 IRF4 BCL11A CUL7 BAP1 KANSL2 AGO3 ALMS1 NFKB2 WDR20 MCRS1 TAF4 SPEN	3.22e-04	1429	145	16	35140242
Pubmed	Ctip1 Controls Acquisition of Sensory Area Identity and Establishment of Sensory Input Fields in the Developing Neocortex.	GBX2 BCL11A DBP	3.53e-04	33	145	3	27100196
Pubmed	Serum and glucocorticoid-induced kinase (SGK) 1 and the epithelial sodium channel are regulated by multiple with no lysine (WNK) family members.	WNK1 WNK3	3.58e-04	7	145	2	20525693
Pubmed	RNF126-Mediated MRE11 Ubiquitination Activates the DNA Damage Response and Confers Resistance of Triple-Negative Breast Cancer to Radiotherapy.	ATR RNF126	3.58e-04	7	145	2	36563124
Pubmed	Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumab.	TGFBR1 PIK3CG	3.58e-04	7	145	2	18625725
Pubmed	Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint.	ATR SKP2	3.58e-04	7	145	2	20818375
Pubmed	The mouse mahogany locus encodes a transmembrane form of human attractin.	ATRN SIGLEC1	3.58e-04	7	145	2	10086356
Pubmed	Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts.	MYH6 MYH8	3.58e-04	7	145	2	16819597
Interaction	AP2B1 interactions	LIMA1 WNK1 BAP1 TBC1D8 TGFBR1 ALMS1 SH3D19 ITSN2 OSBPL10 FGFR1 PLOD2 WNK3 HTT	2.46e-06	373	142	13	int:AP2B1
Interaction	GPR156 interactions	OBSL1 PLCD3 KANSL2 RPUSD2 MCRS1 ZNF574	1.08e-05	71	142	6	int:GPR156
Cytoband	14q12	AKAP6 MYH6 IPO4 NYNRIN	2.80e-05	55	144	4	14q12
GeneFamily	Cullins	CUL9 CUL7	7.65e-04	8	96	2	1032
GeneFamily	Cyclins\|F-boxes other	FBH1 FBXO8 FBXO42	1.15e-03	39	96	3	560
GeneFamily	Oxysterol binding proteins\|Pleckstrin homology domain containing	OSBPL7 OSBPL10	1.78e-03	12	96	2	670
GeneFamily	Ankyrin repeat domain containing	ANKRD23 ANKZF1 ANKRD27 NFKB2 ASB1 SOWAHB	1.84e-03	242	96	6	403
GeneFamily	WD repeat domain containing\|GRAM domain containing\|BEACH domain containing	TBC1D9 TBC1D8	2.09e-03	13	96	2	1146
GeneFamily	Myosin heavy chains	MYH6 MYH8	2.80e-03	15	96	2	1098
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	ZNF142 EPPK1 MFHAS1 OBSL1 DAG1 ERMP1 IPO4 FAM171A1 ESYT2 SLC12A4 NFKB2 FGFR1 IL17RA LTBP3 TMCO3 HTT	1.04e-06	681	143	16	M5314
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	ZNF142 EPPK1 MFHAS1 DAG1 ERMP1 IPO4 FAM171A1 ESYT2 SLC12A4 NFKB2 FGFR1 IL17RA LTBP3 TMCO3 HTT	7.37e-06	703	143	15	MM1055
Coexpression	GSE38304_MYC_NEG_VS_POS_GC_BCELL_UP	EPHX1 MAP4K3 CHDH BBS9 ZBTB37 RFTN1 ALMS1 MED13	1.47e-05	200	143	8	M9273
Coexpression	GSE8685_IL15_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_DN	CUL9 HEATR1 MFNG PIK3CG GAL3ST3 IL17RA XKRX	2.89e-05	160	143	7	M338
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IRF4 BCL11A TBC1D9 FCRL3 PIK3CG OSBPL10 KCNN3	3.67e-06	197	144	7	0f489d26e4013d1b5a90559856ed2de32a0bb772
ToppCell	BAL-Severe-cDC_10\|Severe / Compartment, Disease Groups and Clusters	IRF4 CBLB LRCH3 TBC1D8 RFTN1 TBC1D4 NFKB2	3.92e-06	199	144	7	54bdadd04abaf8caa948b0177c037bc089ca07e6
ToppCell	Transverse-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	DNHD1 MFHAS1 ZNF213 FBXO42 TJAP1 SIGLEC1 CRAMP1	3.92e-06	199	144	7	fd75dccb37d96448edf72b7d042b06833d4ead24
ToppCell	E18.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_B\|E18.5-samps / Age Group, Lineage, Cell class and subclass	THSD4 ZNF704 DNAH1 ALMS1 ASB1 FGFR1	5.64e-06	137	144	6	b553958e7e6dcd887d860e34d3983cbb85cefaa6
ToppCell	LPS_only-Myeloid-Dendritic_cells-mDC\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IRF4 BCL11A TBC1D8 RFTN1 TBC1D4 PIK3CG	8.45e-06	147	144	6	26bd9d89e2e7b841cc18030bb7cebb642b987183
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	ARHGAP32 LIMA1 ZNF213 ERMP1 PALB2 MYO15A	1.23e-05	157	144	6	2c1219ee19a6246a3b9f5c2c1a37f26ea934a822
ToppCell	droplet-Liver-LIVER-NPC-1m-Lymphocytic-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF13B ATR CIART CUL9 FGFR1 HSF4	1.63e-05	165	144	6	8c7a6f9e2ca0ce077426d3d0726e3f5a4c03b296
ToppCell	facs-Lung-EPCAM-24m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF13B ZNF446 ESYT2 TBC1D4 OSBPL10 KCNN3	1.74e-05	167	144	6	961e722442d786ab15d1e490941d2be265a9057a
ToppCell	facs-Lung-EPCAM-24m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF13B ZNF446 ESYT2 TBC1D4 OSBPL10 KCNN3	1.74e-05	167	144	6	3760efc35d4e7e9c2da1a20f9795ddea397e2206
ToppCell	LPS-antiTNF-Myeloid-Dendritic_cells-mDC\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IRF4 BCL11A TBC1D9 TBC1D8 FAT2 PIK3CG	1.80e-05	168	144	6	2dca1c4a33b6da9357fa3b2a523af19baab1c21c
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRG1 MAP4K3 WHAMM BCL11A RPUSD2 SPEN	1.87e-05	169	144	6	4e1322cc5e1733e9fb19e08f739a30206f43cea8
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HEATR1 ARHGAP4 PIK3CG IL17RA TAF4 PNPLA7	1.87e-05	169	144	6	305cedbd97059029d7d2a248a8a4b6cfe281aa54
ToppCell	NS-critical-d_0-4-Epithelial-FOXN4+\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DBP IPO4 ZNF446 NGDN PLCD3 PLOD2	2.06e-05	172	144	6	a00bb44d33658cb3a98accd6b60f3ce964c425b4
ToppCell	TCGA-Thymus-Primary_Tumor-Thymoma-Type_AB\|TCGA-Thymus / Sample_Type by Project: Shred V9	THSD4 MYH6 GBX2 RUNX1T1 GAL3ST3 FGFR1	2.27e-05	175	144	6	50f9b994bdd389158f92f891944ea81b2fb15eef
ToppCell	droplet-Lung-nan-18m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF142 TBC1D9 TBC1D8 DGLUCY TBC1D4 ASB1	2.35e-05	176	144	6	24b2e94ee5defcefb64a1f2447a2cc71b015b0fd
ToppCell	Control-B_cells\|Control / group, cell type (main and fine annotations)	IRF4 BCL11A TBC1D9 FCRL3 PIK3CG OSBPL10	2.35e-05	176	144	6	9125caa27bf790f6b1b960a86c09b4bcb1b58641
ToppCell	droplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZNF142 TBC1D9 TBC1D8 DGLUCY TBC1D4 ASB1	2.42e-05	177	144	6	f360f7099570d248531897b96e0de282e58f59e9
ToppCell	IIH-CD8-antiviral_CD4\|IIH / Condition, Cell_class and T cell subcluster	KIF13B MFHAS1 ZSWIM6 CBLB PHC2 KRBA1	2.42e-05	177	144	6	fe73608c40701eca88b260aeb5c0640d7bee72ba
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_4\|343B / Donor, Lineage, Cell class and subclass (all cells)	CUL9 IRF4 CUL7 TBC1D4 NFKB2 XKRX	2.58e-05	179	144	6	c09c3eed43d1aa3b7aa8f3021e6f2737840cde16
ToppCell	LV\|World / Chamber and Cluster_Paper	AKAP6 THSD4 BCL11A RUNX1T1 DGLUCY TBC1D4	2.66e-05	180	144	6	5ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCell	facs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHDH BCL11A TBC1D8 TGFBR1 CMAHP XKRX	2.66e-05	180	144	6	bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCell	facs-Marrow-B-cells-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHDH BCL11A TBC1D8 TGFBR1 CMAHP XKRX	2.66e-05	180	144	6	839defb40f7cfb2711e9025194de636533f51bcd
ToppCell	facs-Marrow-B-cells-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHDH BCL11A TBC1D8 TGFBR1 CMAHP XKRX	2.66e-05	180	144	6	82965ed1b72a1873c24dd4553d39681596057316
ToppCell	facs-Kidney-nan-3m\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRN MYH6 ERMP1 TEK FBH1 MOG	2.83e-05	182	144	6	4c5d14e33ebdf117b5aa9e2f57aaa89aa51f72bf
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 ZNF704 PEG3 RUNX1T1 NKD1 FGFR1	2.92e-05	183	144	6	12daaea821e49bc94a01e2496331e92a80d27339
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	MAP4K3 ZNF213 SKP2 TGFBR1 SLC12A4 USP42	3.10e-05	185	144	6	daea170d827226dda6750bf1838ffd82f070c4d4
ToppCell	saliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway-secretory_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DAB2IP LPCAT4 TBC1D9 NYNRIN SH3D19 OSBPL10	3.30e-05	187	144	6	6e5c38425b6b1d4774f8dcea7e146f1eab785c3e
ToppCell	saliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DAB2IP LPCAT4 TBC1D9 NYNRIN SH3D19 OSBPL10	3.30e-05	187	144	6	43ef900b76f3c38bd8ce9858201124130c743d56
ToppCell	390C-Myeloid-Dendritic-cDC_activated\|390C / Donor, Lineage, Cell class and subclass (all cells)	IRF4 BCL11A TBC1D9 TBC1D8 RFTN1 TBC1D4	3.30e-05	187	144	6	60c2576f31a60f819deb9ec500d1f714b469df4e
ToppCell	COPD-Myeloid-DC_Mature\|COPD / Disease state, Lineage and Cell class	IRF4 BCL11A TBC1D8 TGFBR1 RFTN1 TBC1D4	3.40e-05	188	144	6	de93ccb53edb8599da9e312db0e3af604c21f673
ToppCell	343B-Lymphocytic-ILC-ILC-1\|343B / Donor, Lineage, Cell class and subclass (all cells)	HEATR1 TASOR2 ZBTB37 DPP9 SLC12A4 HTT	3.40e-05	188	144	6	8f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCell	CF-Lymphoid\|CF / Disease state, Lineage and Cell class	ATR IRF4 CBLB TASOR2 RFTN1 FCRL3	3.93e-05	193	144	6	11de07d13a7da223990b56fa89ba7fc1c3dd0122
ToppCell	facs-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	P3H3 PEG3 DBP ESYT2 FGFR1 LTBP3	4.16e-05	195	144	6	c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCell	droplet-Tongue-TONGUE\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CIART PEG3 LPCAT4 ERMP1 DBP WNK1	4.28e-05	196	144	6	44a30b1a5f3d8c845e5f3bd17d8102a7449f555b
ToppCell	droplet-Tongue-TONGUE-1m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CIART PEG3 LPCAT4 ERMP1 DBP WNK1	4.28e-05	196	144	6	9935bdb10789e8cfc922dca526ca3bf8317fe270
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CIART PEG3 LPCAT4 ERMP1 DBP WNK1	4.28e-05	196	144	6	a85f5f1e6acc798e9e02b1a21e0ffe87a323c333
ToppCell	facs-Lung-nan\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 DAG1 DBP ESYT2 FGFR1 LTBP3	4.28e-05	196	144	6	b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCell	facs-Lung-nan-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 DAG1 DBP ESYT2 FGFR1 LTBP3	4.28e-05	196	144	6	787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD4 PEG3 DAG1 NFKB2 KCNN3 FGFR1	4.41e-05	197	144	6	5bc11aff92da2a0aca8473f997fe7a99f3cae75d
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-B-B_cell-B_naive\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BCL11A TBC1D9 ARHGAP4 MFNG FCRL3 OSBPL10	4.41e-05	197	144	6	e4b4fa219322b3250b482f8e242f41e8b05485db
ToppCell	LPS_only-Hematopoietic_Myeloid-Dendritic_cells\|LPS_only / Treatment groups by lineage, cell group, cell type	IRF4 TBC1D8 RFTN1 TBC1D4 PIK3CG SIGLEC1	4.41e-05	197	144	6	59ddd8ff7dddf3747b988374e1a4d80959db803e
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	P3H3 IRF4 BCL11A PIK3CG AIFM3 IL17RA	4.53e-05	198	144	6	c64238379798ae6b292cc1914d60548c88e652de
ToppCell	COVID-19-Myeloid-Migratory_DC\|Myeloid / Condition, Lineage and Cell class	IRF4 BCL11A CBLB TBC1D8 RFTN1 TBC1D4	4.53e-05	198	144	6	90f3b227cbc61c268d6d94bc9945a08d83d2d3d5
ToppCell	Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	LIMA1 RUNX1T1 SH3D19 FGFR1 LTBP3 PLOD2	4.66e-05	199	144	6	40de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCell	facs-Trachea-nan-3m-Mesenchymal\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 PEG3 DAG1 FGFR1 LTBP3 PLOD2	4.66e-05	199	144	6	67f78c070c56e44fba36542041bf7fa1c291807c
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T\|COVID-19_Mild / Disease, condition lineage and cell class	LIMA1 IRF4 CBLB WNK1 TBC1D4 FGFR1	4.66e-05	199	144	6	f307d4887b28cf60a591439e278fd668409cb104
ToppCell	facs-Trachea-nan-3m-Mesenchymal-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 PEG3 DAG1 FGFR1 LTBP3 PLOD2	4.66e-05	199	144	6	1ae244b563f85c1ee8d22698f478c842a4d9c7f5
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-3\|TCGA-Cervix / Sample_Type by Project: Shred V9	TICRR ERMP1 SNIP1 FAT2 SPEN	4.81e-05	122	144	5	1ed865f0ecfe304fb86313ff51c04e9052357270
ToppCell	PBMC-Mild-cDC_2\|Mild / Compartment, Disease Groups and Clusters	DAB2IP THSD4 EPPK1 FA2H RUNX1T1	7.78e-05	135	144	5	cb9d834f8301cf53f20e09c3f4cb6a148690196a
ToppCell	Cerebellum-Hematopoietic-MICROGLIA\|Cerebellum / BrainAtlas - Mouse McCarroll V32	IRF4 ARHGAP4 PIK3CG SIGLEC1 CMAHP	8.93e-05	139	144	5	75cca1e6c1af289987d5d98455e9c6db81ecdd64
ToppCell	Cerebellum-Hematopoietic-MICROGLIA-MI1(C1qb)-MICROGLIA_Microglia.C1qb.Mrc1-Tmem119_(Resident_macrophage)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	IRF4 ARHGAP4 PIK3CG SIGLEC1 CMAHP	8.93e-05	139	144	5	a077ce50f6d6746d80de35abed5b6dc35b1145b9
ToppCell	Cerebellum-Hematopoietic-MICROGLIA-MI1(C1qb)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	IRF4 ARHGAP4 PIK3CG SIGLEC1 CMAHP	8.93e-05	139	144	5	de34e2f51f6fda638357abb662c111a20b83e70b
ToppCell	Cerebellum-Hematopoietic-MICROGLIA-MI1(C1qb)-MICROGLIA_Microglia.C1qb.Mrc1-Tmem119_(Resident_macrophage)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	IRF4 ARHGAP4 PIK3CG SIGLEC1 CMAHP	8.93e-05	139	144	5	0ae117308bd10d3a7d2688794c69dc5a31cfca5f
ToppCell	Cerebellum-Hematopoietic-MICROGLIA-MI1(C1qb)-MICROGLIA_Microglia.C1qb.Mrc1-Tmem119_(Resident_macrophage)--\|Cerebellum / BrainAtlas - Mouse McCarroll V32	IRF4 ARHGAP4 PIK3CG SIGLEC1 CMAHP	8.93e-05	139	144	5	fac6a3100a277efa1db250e0c576be1a0c901e6d
ToppCell	Cerebellum-Hematopoietic\|Cerebellum / BrainAtlas - Mouse McCarroll V32	IRF4 ARHGAP4 PIK3CG SIGLEC1 CMAHP	8.93e-05	139	144	5	3913c3828ad4cb5c71380519d0cf5f195e53c51d
ToppCell	LPS_only-Myeloid-Dendritic_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IRF4 BCL11A TBC1D8 PIK3CG SIGLEC1	1.20e-04	148	144	5	cb9365663f9cba35d47b5dd9079f42e88b70d915
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LMNTD2 BCL11A TBC1D9 ITSN2 LTBP3	1.24e-04	149	144	5	48fca6ae33d7722c024b43ce04f4dbce7b6b424b
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	SZT2 CBLB TASOR2 AGO3 SPEN	1.24e-04	149	144	5	768877bade04ca0321593b8470b5011ad8270431
ToppCell	PND01-Immune-Immune_Myeloid-DC-cDC2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SZT2 ARHGAP4 RFTN1 PIK3CG FBXO42	1.36e-04	152	144	5	cefc0ab592e99badf145fb95adf9906cb81be81c
ToppCell	PND01-Immune-Immune_Myeloid-DC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SZT2 ARHGAP4 RFTN1 PIK3CG FBXO42	1.36e-04	152	144	5	c8faa83dcaddb2ce2bb890f90dd8e676f7dcb1b3
ToppCell	PND01-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SZT2 ARHGAP4 RFTN1 PIK3CG FBXO42	1.36e-04	152	144	5	c3f00beb8b6fde99263d5ed6bbe3c2415d02f91d
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MFHAS1 IRF4 MFNG TBC1D4 OSBPL7	1.44e-04	154	144	5	ec920cae12ea1d14b6c973f6e903f895f80e3c50
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRRG1 ZNF132 MAP4K3 PHC2 KCNN3	1.53e-04	156	144	5	d411116d54add2d4fe649a97ac54cb94c085312f
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHDH IRF4 BCL11A PALB2 XKRX	1.78e-04	161	144	5	ed93cb6c133855a5c244821e1a260aae8ab4df9a
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHDH IRF4 BCL11A PALB2 XKRX	1.78e-04	161	144	5	0089d7bb305c592392791862a3341fc92af8f3e2
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EPPK1 CHDH BCL11A CEMP1 PIK3CG	1.99e-04	165	144	5	34fd00be2b28716c871ad9fb356de84a299a0c01
ToppCell	droplet-Lung-LUNG-1m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP32 CHDH BCL11A TBC1D8 XKRX	2.05e-04	166	144	5	6e6075d0c913e2516083f6dcab21d5878bcef7a4
ToppCell	droplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP32 CHDH BCL11A TBC1D8 XKRX	2.05e-04	166	144	5	1ca888ae8168707493f19ee52a89d7c70e6cb51d
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP32 CHDH BCL11A TBC1D8 XKRX	2.05e-04	166	144	5	4fbe44e0aea197893614cd55f83119aa0f73ee53
ToppCell	droplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP32 CHDH BCL11A TBC1D8 XKRX	2.05e-04	166	144	5	4cba4ca1aa2321b9ef7cd230932b890d2434a252
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF13B KIFC2 ALMS1 FBXO42 SIGLEC1	2.11e-04	167	144	5	f5bffa77061baec0ba87bd688a047595f32534db
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	DAG1 ZNF213 ZSWIM6 KRBA1 MYO15A	2.16e-04	168	144	5	ca94b29c1030484143a77f2df06dad74d2c6136e
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PEG3 ANKRD23 KIFC2 AIFM3 SOWAHB	2.23e-04	169	144	5	d382a76d85875663502cc7dde2e3e0682605768e
ToppCell	droplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PALB2 TBC1D9 TBC1D8 TBC1D4 FGFR1	2.29e-04	170	144	5	bf589c4297ccc90e5f51e3d0fcc229548af4fcef
ToppCell	LPS-antiTNF-Myeloid-Dendritic_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IRF4 BCL11A TBC1D8 FAT2 PIK3CG	2.29e-04	170	144	5	3cbeea6bfa500928c413b1c6129f6dedc769cd1e
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATR FBH1 IGHMBP2 FBXO42 KCNN3	2.29e-04	170	144	5	833b4f44ea1fa673dfc6b43ce45a79fe68ae3b05
ToppCell	normal-na-Lymphocytic_B-B_plasma-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	HYOU1 IRF4 TBC1D9 FBH1 KCNN3	2.29e-04	170	144	5	c5b87974dfddf9780051f7f5693eeeb0c606a3fe
ToppCell	droplet-Spleen-nan-18m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP32 CHDH TBC1D8 FGFR1 PLOD2	2.35e-04	171	144	5	4e856441063e9825b6f87a1d3dd19c77dae4662c
ToppCell	Int-URO-Lymphocyte-T_NK-dnT\|Int-URO / Disease, Lineage and Cell Type	LIMA1 FBXO8 OSBPL7 RPUSD2 PNPLA7	2.41e-04	172	144	5	e70299573da1679d6d286c3a43699cbff76e207d
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP32 CHDH BCL11A CMAHP XKRX	2.48e-04	173	144	5	4f0c065e876197ad8cae7856669f09e37ecafa3f
ToppCell	droplet-Lung-nan-21m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHDH BCL11A ANKZF1 TBC1D8 XKRX	2.48e-04	173	144	5	8fb32a9f2dbec16de840d55b4db7e7718f5a2a7a
ToppCell	droplet-Lung-nan-21m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHDH BCL11A ANKZF1 TBC1D8 XKRX	2.48e-04	173	144	5	f663571aaae2365660a8b526c355f4bd1a124a74
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP32 CHDH BCL11A CMAHP XKRX	2.48e-04	173	144	5	9bbea566964281f47bf75d665b7d69ba8326e207
ToppCell	Healthy-Plasmablast\|World / disease group, cell group and cell class	TICRR HYOU1 FA2H IRF4 OSBPL10	2.55e-04	174	144	5	6becb456d8f44a1224c6d42be78d4c8cdb51f199
ToppCell	nucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-pDC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	IRF4 BCL11A TGFBR1 RFTN1 PIK3CG	2.61e-04	175	144	5	37c2d4e0b6e9a3171931797ce9a54f3347288e57
ToppCell	metastatic_Brain-Endothelial_cells-Stalk-like_ECs\|Endothelial_cells / Location, Cell class and cell subclass	LMNTD2 RUNX1T1 KRBA1 TAF4 PLOD2	2.61e-04	175	144	5	f6a6db992e803d36c866a91706b02f67e0fd3e09
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	HYOU1 FA2H IRF4 FBH1 KCNN3	2.61e-04	175	144	5	3b5346fba617292de71963b6175e85a4f182fe30
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 CHDH TEK NKD1 PIK3CG	2.61e-04	175	144	5	f24b664b9056b5976bf2222e8013f15c09e049ad
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	HYOU1 FA2H IRF4 FBH1 KCNN3	2.68e-04	176	144	5	dc4e939a07bad21ab36181f9588df3fa662f9a92
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 KIF13B MYH6 PEG3 TBC1D4	2.68e-04	176	144	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	Control-Lymphoid_P-Plasmablast\|Control / Disease group, lineage and cell class	HYOU1 FA2H IRF4 FBH1 KCNN3	2.68e-04	176	144	5	4b4416f342b732d2cc60133838728880326257d8
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-Plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HYOU1 IRF4 OOSP2 PLCD3 CMAHP	2.68e-04	176	144	5	606704098bfdf8bfef740a3544a372fae1e75969
ToppCell	Control-Lymphoid_P\|Control / Disease group, lineage and cell class	HYOU1 FA2H IRF4 FBH1 KCNN3	2.68e-04	176	144	5	d895a6b295cd649273ff80ad7785a3e0ae4c728a
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-plasma_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HYOU1 IRF4 OOSP2 PLCD3 CMAHP	2.68e-04	176	144	5	acb9e29773030f6452a069f8f7e53eab68ab7bd3
ToppCell	Control-Myeloid-pDC\|Control / Disease state, Lineage and Cell class	IRF4 BCL11A TGFBR1 RFTN1 PIK3CG	2.75e-04	177	144	5	3940663bb5b45b2ca9f772550380a516c53e410b
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_B-plasmablast-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TICRR HYOU1 FA2H IRF4 KCNN3	2.75e-04	177	144	5	d2c1f46913ac00bbc0bb9320d5652edc01b34179
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_B-plasmablast\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TICRR HYOU1 FA2H IRF4 KCNN3	2.75e-04	177	144	5	65e090aad0ffb737ce034e25bd5b12a0b1dd9684
ToppCell	Posterior_cortex-Macroglia-OLIGODENDROCYTE-O2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FA2H CHDH SIGLEC1 MOG	2.77e-04	97	144	4	7b17dc28454949a23701ab127300a29a8899d7d6
ToppCell	Posterior_cortex-Macroglia-OLIGODENDROCYTE-O2-Tfr\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FA2H CHDH SIGLEC1 MOG	2.77e-04	97	144	4	4b74b3c5b9590a8215b7370b37e9723e9f040b9c
ToppCell	Control-Myeloid-pDC\|World / Disease state, Lineage and Cell class	IRF4 BCL11A TGFBR1 RFTN1 PIK3CG	2.83e-04	178	144	5	20ef63d925e67ddd5955832312ca8574a6f838a4
Drug	C768-0445; Up 200; 10uM; MCF7; HT_HG-U133A_EA	SZT2 CUL9 DBP ANKZF1 CBLB ZNF446 TBC1D8 RFTN1 ALMS1 TJAP1 ASB1	3.21e-08	189	143	11	973_UP
Drug	Merbromin [129-16-8]; Up 200; 5uM; MCF7; HT_HG-U133A	THSD4 MYH8 LPCAT4 OBSL1 RUNX1T1 WNK1 MFNG IGHMBP2 FGFR1	4.27e-06	196	143	9	4722_UP
Drug	pioglitazone HCl; Up 200; 10uM; MCF7; HT_HG-U133A	CUL7 SKP2 BBS9 TBC1D4 ALMS1 IGHMBP2 FBXO42 FGFR1 HTT	4.63e-06	198	143	9	7083_UP
Drug	Verteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT_HG-U133A	EPHX1 PRRG1 ATRN DAG1 ERMP1 DBP IL17RA PLOD2	8.32e-06	161	143	8	3556_DN
Drug	Cloperastine hydrochloride [14984-68-0]; Up 200; 11uM; PC3; HT_HG-U133A	HYOU1 P3H3 IRF4 RUNX1T1 CEMP1 TGFBR1 NYNRIN TJAP1	2.37e-05	186	143	8	4271_UP
Drug	Conessine [546-06-5]; Down 200; 11.2uM; MCF7; HT_HG-U133A	EPPK1 LPCAT4 WNK1 SKP2 MFNG TBC1D4 NFKB2 FGFR1	3.20e-05	194	143	8	2792_DN
Drug	Levamisole hydrochloride [16595-80-5]; Up 200; 16.6uM; HL60; HG-U133A	AKAP6 EPHX1 IRF4 RUNX1T1 ANKZF1 TBC1D4 FBXO42 ZNF574	3.32e-05	195	143	8	1410_UP
Drug	Sulfadimethoxine [122-11-2]; Up 200; 12.8uM; MCF7; HT_HG-U133A	DAG1 WNK1 RFTN1 MFNG NYNRIN IGHMBP2 TJAP1 FGFR1	3.45e-05	196	143	8	4724_UP
Drug	Tranylcypromine hydrochloride [1986-47-6]; Up 200; 23.6uM; MCF7; HT_HG-U133A	THSD4 OBSL1 CUL7 RUNX1T1 SKP2 RFTN1 FGFR1 HSF4	3.70e-05	198	143	8	5996_UP
Drug	Diperodon hydrochloride [537-12-2]; Down 200; 9.2uM; MCF7; HT_HG-U133A	ARHGAP32 CUL9 CUL7 SKP2 NGDN TGFBR1 RFTN1 NFKB2	3.84e-05	199	143	8	6836_DN
Drug	Lysergol [602-85-7]; Down 200; 15.8uM; HL60; HT_HG-U133A	MFHAS1 WNK1 SKP2 RFTN1 ALMS1 IGHMBP2 TJAP1 HTT	3.84e-05	199	143	8	1325_DN
Drug	betaine	P3H3 CHDH CBLB WNK1 MMAA NFKB2 PLOD2 CRAMP1	3.98e-05	200	143	8	CID000000247
Disease	Squamous cell carcinoma of lung	ATR MAP4K3 FGFR1 WNK3	1.62e-05	32	141	4	C0149782
Disease	hydroxy-leucine measurement	DAB2IP KIF13B ZNF213 ALMS1	6.39e-05	45	141	4	EFO_0005276
Disease	3-M syndrome	OBSL1 CUL7	6.78e-05	3	141	2	cv:C1848862
Disease	3-M syndrome (is_implicated_in)	OBSL1 CUL7	6.78e-05	3	141	2	DOID:0060241 (is_implicated_in)
Disease	nephrotic syndrome type 20 (implicated_via_orthology)	TBC1D9 TBC1D8	1.35e-04	4	141	2	DOID:0070357 (implicated_via_orthology)
Disease	pseudohypoaldosteronism (implicated_via_orthology)	WNK1 WNK3	3.36e-04	6	141	2	DOID:4479 (implicated_via_orthology)
Disease	Large cell carcinoma of lung	ATR FGFR1 WNK3	4.79e-04	32	141	3	C0345958
Disease	Bone neoplasms	BAP1 PLOD2	6.23e-04	8	141	2	C0005967
Disease	Malignant Bone Neoplasm	BAP1 PLOD2	6.23e-04	8	141	2	C0279530
Disease	blindness (implicated_via_orthology)	PNPLA7 MYO15A	6.23e-04	8	141	2	DOID:1432 (implicated_via_orthology)
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	DNHD1 CUL7 TEK BAP1 WNK3	7.42e-04	148	141	5	C0279702
Disease	Experimental Autoimmune Encephalomyelitis	CBLB MOG	7.98e-04	9	141	2	C0014072
Disease	autosomal dominant hyaline body myopathy (implicated_via_orthology)	MYH6 MYH8	9.95e-04	10	141	2	DOID:0111269 (implicated_via_orthology)
Disease	distal arthrogryposis type 2B3 (implicated_via_orthology)	MYH6 MYH8	9.95e-04	10	141	2	DOID:0111602 (implicated_via_orthology)
Disease	distal arthrogryposis type 1 (implicated_via_orthology)	MYH6 MYH8	9.95e-04	10	141	2	DOID:0111596 (implicated_via_orthology)
Disease	dilated cardiomyopathy 1S (implicated_via_orthology)	MYH6 MYH8	9.95e-04	10	141	2	DOID:0110454 (implicated_via_orthology)
Disease	congenital myopathy 6 (implicated_via_orthology)	MYH6 MYH8	9.95e-04	10	141	2	DOID:0080719 (implicated_via_orthology)
Disease	inclusion body myositis (implicated_via_orthology)	MYH6 MYH8	9.95e-04	10	141	2	DOID:3429 (implicated_via_orthology)
Disease	distal arthrogryposis type 2A (implicated_via_orthology)	MYH6 MYH8	9.95e-04	10	141	2	DOID:0111605 (implicated_via_orthology)
Disease	familial hypertrophic cardiomyopathy (implicated_via_orthology)	MYH6 MYH8	9.95e-04	10	141	2	DOID:0080326 (implicated_via_orthology)
Disease	Neoplasm of uncertain or unknown behavior of breast	PALB2 BAP1 FGFR1	9.97e-04	41	141	3	C0496956
Disease	Breast adenocarcinoma	PALB2 BAP1 FGFR1	9.97e-04	41	141	3	C0858252
Disease	Drug-induced agranulocytosis, response to clozapine	FAM171A1 KANSL2 CDH9	1.07e-03	42	141	3	GO_0097338, HP_0012235
Disease	nasopharynx carcinoma (is_marker_for)	DAB2IP ATR SPEN	1.15e-03	43	141	3	DOID:9261 (is_marker_for)
Disease	distal myopathy (implicated_via_orthology)	MYH6 MYH8	1.45e-03	12	141	2	DOID:11720 (implicated_via_orthology)
Disease	myotonia congenita (implicated_via_orthology)	MYH6 MYH8	1.45e-03	12	141	2	DOID:2106 (implicated_via_orthology)
Disease	cognitive function measurement, self reported educational attainment	AKAP6 BCL11A RUNX1T1 ALMS1 SH3D19 CMAHP CDH9	1.64e-03	355	141	7	EFO_0004784, EFO_0008354
Disease	restrictive cardiomyopathy (implicated_via_orthology)	MYH6 MYH8	1.71e-03	13	141	2	DOID:397 (implicated_via_orthology)
Disease	Medulloblastoma	SKP2 PALB2 PIK3CG	1.78e-03	50	141	3	C0025149
Disease	Hypodontia	FGFR1 LTBP3	1.99e-03	14	141	2	C0020608
Disease	diffuse large B-cell lymphoma	IRF4 ITSN2	1.99e-03	14	141	2	EFO_0000403
Disease	distal arthrogryposis (implicated_via_orthology)	MYH6 MYH8	2.29e-03	15	141	2	DOID:0050646 (implicated_via_orthology)
Disease	Diffuse Large B-Cell Lymphoma	SKP2 PIK3CG SPEN	2.34e-03	55	141	3	C0079744
Disease	clonal hematopoiesis mutation measurement	CBLB TBC1D4 AIFM3	2.34e-03	55	141	3	EFO_0020949
Disease	focal segmental glomerulosclerosis	IPO4 ALMS1	2.60e-03	16	141	2	EFO_0004236
Disease	Synostotic Posterior Plagiocephaly	BBS9 FGFR1	2.60e-03	16	141	2	C1833340
Disease	2-hydroxyglutarate measurement	DGLUCY GAL3ST3	2.60e-03	16	141	2	EFO_0021506
Disease	Craniosynostosis, Type 1	BBS9 FGFR1	2.60e-03	16	141	2	C4551902
Disease	Acrocephaly	BBS9 FGFR1	2.60e-03	16	141	2	C0030044
Disease	Trigonocephaly	BBS9 FGFR1	2.60e-03	16	141	2	C0265535
Disease	Scaphycephaly	BBS9 FGFR1	2.60e-03	16	141	2	C0265534
Disease	Synostotic Anterior Plagiocephaly	BBS9 FGFR1	2.60e-03	16	141	2	C2931150
Disease	Metopic synostosis	BBS9 FGFR1	2.60e-03	16	141	2	C1860819
Disease	PR interval	AKAP6 KIF13B DAG1 CUL9 NGDN TJAP1 FGFR1 CMAHP	2.69e-03	495	141	8	EFO_0004462
Disease	information processing speed, response to cranial radiation therapy	CUL9 FAM171A1 SIGLEC1	2.72e-03	58	141	3	EFO_0004363, EFO_0010950
Disease	Pulmonary Emphysema	EPHX1 TGFBR1	2.94e-03	17	141	2	C0034067
Disease	Brachycephaly	BBS9 FGFR1	2.94e-03	17	141	2	C0221356
Disease	Malignant Neoplasms	ATR SKP2 BAP1 FGFR1	3.37e-03	128	141	4	C0006826
Disease	arterial stiffness measurement	DAB2IP RNF126 TAF4	3.60e-03	64	141	3	EFO_0004517
Disease	Hereditary Non-Polyposis Colon Cancer Type 2	EPHX1 PALB2	3.68e-03	19	141	2	C1333991
Disease	Colorectal cancer, hereditary nonpolyposis, type 1	EPHX1 PALB2	3.68e-03	19	141	2	C2936783
Disease	Craniosynostosis	BBS9 FGFR1	4.07e-03	20	141	2	C0010278
Disease	periodontitis	AKAP6 DAB2IP THSD4 EPPK1 OSBPL10	4.44e-03	223	141	5	EFO_0000649
Disease	Infiltrating duct carcinoma of female breast	ATR FGFR1	4.49e-03	21	141	2	C3165106

Protein segments in the cluster

Peptide	Gene	Start	Entry
HLEKRERPPDHQHSA	ESYT2	656	A0FGR8
PAVPRLTSAEDRHRH	SLC4A9	356	Q96Q91
STPLHVAVRTRHPDC	ANKRD23	211	Q86SG2
ARHFHTEERLSTPHP	AIFM3	46	Q96NN9
DVNHHLTPDVQPRFS	ASB1	171	Q9Y576
TSEHPQLDRHPCAFR	ALMS1	2591	Q8TCU4
ELAKAHNSHARPEPR	BAP1	136	Q92560
VPERVFHLSAFRHPR	DNHD1	4576	Q96M86
IHNIDEQPRPLTDSH	AGO3	241	Q9H9G7
QRPRSDHQLHRSPFT	CACTIN-AS1	16	Q8N1I8
DHQLHRSPFTVPPRT	CACTIN-AS1	21	Q8N1I8
HITPHIPEINDSIRA	ERMP1	721	Q7Z2K6
HFLPSQVIDHGRVPT	CHDH	401	Q8NE62
NPTRSRSHEPEAIHI	NKD1	291	Q969G9
PSEFRRIESPLKHQH	RAE1	201	P78406
ALHPFVQPTHEREKT	RFTN1	81	Q14699
PSSDEPVFHISHIDR	ITSN2	1506	Q9NZM3
RSPHTPHERFEGLTV	P3H3	501	Q8IVL6
FTPRNIDHDPQEIHL	OOSP2	96	Q86WS3
PFSRDDRGHTPLHVA	ANKRD27	456	Q96NW4
PTHSLVIHDVRPEDQ	OBSL1	1861	O75147
EFHNLPPLRTVTVHL	DAB2IP	261	Q5VWQ8
EPHPVLEAEETRHNR	FBXO42	31	Q6P3S6
HIPAPRPEEFHQRSN	IL17RA	251	Q96F46
EPLVAVPHRIHSTSR	MAP4K3	306	Q8IVH8
PAASPHQRRSAHEEE	FAM171A1	846	Q5VUB5
QPHRSHSEEATREPV	KRBA1	426	A5PL33
LANHVRPRSVPSIHV	LRCH3	691	Q96II8
SPNPFVHELHLSRLQ	LPCAT4	21	Q643R3
RNSSTEIRHRADHPP	LIMA1	91	Q9UHB6
EIRHRADHPPAEVTS	LIMA1	96	Q9UHB6
AEHREIFPNLHRVLP	MFHAS1	646	Q9Y4C4
PEHISNPEDYHRSIR	IRF4	431	Q15306
VLFPEPARTHEEQHN	ERVS71-1	76	P61550
ESHERISPSAALRHP	HIPK4	331	Q8NE63
PDPVALDAHREFLHR	RUNX1T1	421	Q06455
RTPLTQLPAEHHAEA	MYO15A	2071	Q9UKN7
SVLPRPDLHHDVNRF	ATRN	601	O75882
THHPSAFDRVLRLNP	BCL11A	291	Q9H165
FEIHVHRRPQGDRAP	DAG1	591	Q14118
PPDNRLSRHIHHVES	CBLB	566	Q13191
RSTHPHFVRCIIPNE	MYH8	666	P13535
VTIHVEDGNLHPPRF	FAT2	1541	Q9NYQ8
PPEIVISSREDNHAH	KCNN3	216	Q9UGI6
LARQHPEAFSHIPEA	KXD1	91	Q9BQD3
TVHHPARRPISISRD	PDZD9	171	Q8IXQ8
EDHRRTHQPINIPFF	CUL7	806	Q14999
PNALREFFRHIHAPE	FBXO8	211	Q9NRD0
PFREHHIDPTAITRH	PEDS1	116	A5PLL7
ECHRQFRAQPVPAHV	FAM161B	211	Q96MY7
LEHFRTHPTVREQIP	MMAA	376	Q8IVH4
HPPRDHRASSEQALV	LMNTD2	301	Q8IXW0
DFVPELHRNVHPRER	ARHGAP32	51	A7KAX9
ENLHRTFDPHFLRVP	MOG	191	Q16653
RNRRESSPPHSVHSF	PEG3	146	Q9GZU2
KHVFQRPPDRHSDFS	PNPLA7	901	Q6ZV29
NHRHLTAETPRPEVS	BBS9	866	Q3SYG4
PELVIPHRQHRLFTA	SMPD4	531	Q9NXE4
SPERQRSLRPHHDAS	PLOD2	656	O00469
LPIQRTDDTQEHFPH	PALB2	116	Q86YC2
HQPVTRPIRLFHSDL	FA2H	146	Q7L5A8
RPPHVLASHLRFDRA	GAL3ST3	121	Q96A11
RERVPGAPHIAHFTE	DNAH1	2396	Q9P2D7
FPEHVREILEPHLNT	ATR	1446	Q13535
IPAPHTSQEVRIHIR	CEMP1	66	Q6PRD7
PIPVHVSRFAIRSQH	GBX2	326	P52951
PEHELTFDPQRQTVH	HYOU1	121	Q9Y4L1
RHNLPQLPHFRVESF	FBH1	896	Q8NFZ0
SHEPPVQDFISAVHR	HTT	1931	P42858
HDLHQRIDKFRFTPP	EPHX1	61	P07099
RTSEIPFHSEGRHPR	C1orf43	111	Q9BWL3
EDPREAVRLHSPQTH	ANKZF1	351	Q9H8Y5
HTYQLDVVERSPHRP	FGFR1	241	P11362
VPPEIFHFHTRSDVR	DPP9	606	Q86TI2
PQDQHHFLRSSVRPQ	CRAMP1	76	Q96RY5
HFDHSAKRAPRPLID	C1orf100	41	Q5SVJ3
RVHHPPEASVQVHRI	LTBP3	231	Q9NS15
SHPVLTFRAPRAHTV	FCRL3	381	Q96P31
LLRPERDHVEFQHPS	HSF4	91	Q9ULV5
PTLETFQDLLHRHPD	MCRS1	226	Q96EZ8
RPFPVSEHEARHSFQ	ACOD1	321	A6NK06
THRPCSHPRLEGQEF	KANSL2	31	Q9H9L4
DHRRTHQPINIPFFD	CUL9	1136	Q8IWT3
SIPGHETFDPRRHRF	DBP	216	Q10586
LTRAHVECPPAHTRV	CRIPAK	56	Q8N1N5
SVFVDALPHVPEHRR	HEATR1	1381	Q9H583
LTPERIPEVHHISQD	DGLUCY	266	Q7Z3D6
RVDASNTHPDPRFLH	CDH9	346	Q9ULB4
VTSRPEAFQPHHREL	IPO4	146	Q8TEX9
AALRAHRPHVPFRDS	KIFC2	671	Q96AC6
HRPHVPFRDSQLTRL	KIFC2	676	Q96AC6
IHASEPQPHNRTRLV	MFNG	176	O00587
FSVHDIPLGAHQRPE	NYNRIN	1546	Q9P2P1
RGFRFISEQVSHHPP	OSBPL7	571	Q9BZF2
RVPVFSHEVVPDHLR	MED8	96	Q96G25
VRPLRAPRTHETFHE	KIF13B	1061	Q9NQT8
EPVPHRTITSFHELA	RUSC1	306	Q9BVN2
FLRNTVHRHEPPVTA	RPUSD2	206	Q8IZ73
LPSEVHPDINRAHLF	RTL1	396	A6NKG5
HHLAPRTPEVRAAAA	TAF4	41	O00268
EISRLHFRTVPSNPH	SZT2	1441	Q5T011
HRRIADIPIDHPSCS	SNIP1	286	Q8TAD8
TKPRDSTIPRADHHF	TMCO3	256	Q6UWJ1
DEHLRSRPNDPSHAQ	SH3D19	476	Q5HYK7
DPVHSHRVPVDVAYR	EPPK1	731	P58107
DPVHSHRVPVDVAYR	EPPK1	3951	P58107
SRPPLEHVDQHLFTL	RNF126	61	Q9BV68
AVRPPHASINEHILA	WHAMM	731	Q8TF30
DILFPHQPLSRARTH	WDR20	386	Q8TBZ3
RPLTPFHHRVSVSDD	MED13	471	Q9UHV7
TTHPHFVRCIIPNER	MYH6	666	P13533
DPDASPSQHQHRREL	SOWAHB	36	A6NEL2
LRFVAEQVSHHPPIS	OSBPL10	526	Q9BXB5
HRRRCLVPASPEQHV	ARHGAP4	851	P98171
PSHAPDNFRELVHIK	SLC12A4	996	Q9UP95
RTVIHHRVPNEEDPS	TGFBR1	151	P36897
DVPPHERILASASHE	AKAP6	1521	Q13023
HREQQRSHPPVAADA	CIART	366	Q8N365
RPQREHPYEEIHSRV	CMAHP	401	Q9Y471
HLVQRHPPSEESQAF	PIK3CG	136	P48736
DQPLAEHFSPFRVQH	SKP2	171	Q13309
RDALPELQRHFAHSP	TJAP1	436	Q5JTD0
LPNHLRTHSEEIPFT	ZNF132	251	P52740
PHTPQRRFQHTSAVI	PHC2	441	Q8IXK0
APHPDRFSHDRTALV	USP42	1126	Q9H9J4
HQQPHVLRAARAEEP	TICRR	1266	Q7Z2Z1
TRTKHQERPPESHRV	ZBTB37	141	Q5TC79
DHERRPIERSQSPVH	SPEN	716	Q96T58
APEEIRDARHPHVTR	NGDN	216	Q8NEJ9
PRAPSQHIFFVQHIE	PLCD3	101	Q8N3E9
FPPSLNSHDRLRVHQ	IGHMBP2	746	P38935
ERDLHRSLPEHPAFQ	TBC1D8	551	O95759
PFNSPANLARHRLTH	ZNF574	531	Q6ZN55
ERDLHRSLPEHPAFQ	TBC1D9	561	Q6ZT07
RRLHAEPVPTLAFTH	SIGLEC1	1486	Q9BZZ2
FIHSVPRHEVPDILE	TEK	161	Q02763
RRRHASAPSHVQPSD	TBC1D4	336	O60343
EQRQHAHTVLSSPPR	ZNF704	356	Q6ZNC4
QGEVAFPHHPRRSLT	ZNF446	376	Q9NWS9
RRQTVTEGHIPFPQH	PRRG1	111	O14668
DLTRPHHIASVVPNR	ZSWIM6	806	Q9HCJ5
RRRPSVPQEQHSHSA	ZNF213	161	O14771
PEERIHPNTLVKRHF	TASOR2	196	Q5VWN6
VVKHVRRHHPDQADP	ZNF142	1636	P52746
QFLHTRTPPIIHRDL	WNK1	336	Q9H4A3
AQTFPVRHPDRFSPH	THSD4	586	Q6ZMP0
HQHPRTRVENSEPPF	XKRX	426	Q6PP77
RTPPYQVHISHQEAR	SPAG11A	66	Q6PDA7
DHLITHSEERPFRCP	ZNF584	176	Q8IVC4
LQFLHTRTPPIIHRD	WNK3	261	Q9BYP7
IEVDLVTHSDPPRAH	NFKB2	91	Q00653