Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessneural precursor cell proliferation

FOXO3 NES GAK GRN ZNF335 ASPM LRP2 FGFR1 ARHGEF2

1.84e-06233999GO:0061351
GeneOntologyBiologicalProcesspositive regulation of neural precursor cell proliferation

NES GAK ZNF335 ASPM LRP2

4.16e-0580995GO:2000179
GeneOntologyBiologicalProcessregulation of neural precursor cell proliferation

FOXO3 NES GAK ZNF335 ASPM LRP2

4.79e-05135996GO:2000177
GeneOntologyBiologicalProcessneuroblast division

ASPM FGFR1 ARHGEF2

5.74e-0516993GO:0055057
GeneOntologyBiologicalProcessbrain morphogenesis

FOXO3 GAK DUOX2 ZNF335

8.96e-0549994GO:0048854
GeneOntologyBiologicalProcesscellular component maintenance

TPRN GRN SHROOM2 PRICKLE2 INAVA

1.27e-04101995GO:0043954
GeneOntologyCellularComponentATPase inhibitor complex

MAGOH MAGOHB

6.64e-053992GO:1903503
GeneOntologyCellularComponentexon-exon junction subcomplex mago-y14

MAGOH MAGOHB

6.64e-053992GO:1990501
Domain-

ARHGAP23 FRMD7 PLEKHA6 PLEKHN1 ARHGEF17 RASAL3 SHC2 ARHGEF3 ARHGEF2 EPB41L1 EPB41L2

4.28e-0639194112.30.29.30
DomainPH_dom-like

ARHGAP23 FRMD7 PLEKHA6 PLEKHN1 ARHGEF17 RASAL3 SHC2 ARHGEF3 ARHGEF2 EPB41L1 EPB41L2

9.64e-064269411IPR011993
Domain-

MAGOH MAGOHB

2.51e-0529423.30.1560.10
DomainFERM-adjacent

FRMD7 EPB41L1 EPB41L2

3.40e-0513943IPR014847
DomainFA

FRMD7 EPB41L1 EPB41L2

3.40e-0513943SM01195
DomainFA

FRMD7 EPB41L1 EPB41L2

3.40e-0513943PF08736
DomainASD1

SHROOM3 SHROOM2

7.49e-053942PF08688
DomainASD1_dom

SHROOM3 SHROOM2

7.49e-053942IPR014800
DomainMago_nashi

MAGOH MAGOHB

7.49e-053942IPR004023
DomainASD1

SHROOM3 SHROOM2

7.49e-053942PS51306
DomainMago_nashi

MAGOH MAGOHB

7.49e-053942PF02792
DomainASD2

SHROOM3 SHROOM2

1.49e-044942PF08687
DomainBand_4.1_C

EPB41L1 EPB41L2

1.49e-044942IPR008379
Domain4_1_CTD

EPB41L1 EPB41L2

1.49e-044942PF05902
DomainSAB_dom

EPB41L1 EPB41L2

1.49e-044942IPR007477
DomainASD2

SHROOM3 SHROOM2

1.49e-044942PS51307
DomainShroom_fam

SHROOM3 SHROOM2

1.49e-044942IPR027685
DomainSAB

EPB41L1 EPB41L2

1.49e-044942PF04382
DomainASD2_dom

SHROOM3 SHROOM2

1.49e-044942IPR014799
DomainEz/rad/moesin-like

FRMD7 EPB41L1 EPB41L2

1.54e-0421943IPR000798
DomainFERM_CS

FRMD7 EPB41L1 EPB41L2

2.31e-0424943IPR019747
DomainFERM_C

FRMD7 EPB41L1 EPB41L2

2.95e-0426943PF09380
DomainFERM_C

FRMD7 EPB41L1 EPB41L2

3.31e-0427943SM01196
DomainFERM_PH-like_C

FRMD7 EPB41L1 EPB41L2

3.31e-0427943IPR018980
DomainFERM_N

FRMD7 EPB41L1 EPB41L2

6.04e-0433943PF09379
DomainFERM_N

FRMD7 EPB41L1 EPB41L2

6.04e-0433943IPR018979
DomainFERM_M

FRMD7 EPB41L1 EPB41L2

1.60e-0346943PF00373
Domain-

FRMD7 EPB41L1 EPB41L2

1.92e-03499431.20.80.10
DomainFERM_central

FRMD7 EPB41L1 EPB41L2

1.92e-0349943IPR019748
DomainFERM_domain

FRMD7 EPB41L1 EPB41L2

1.92e-0349943IPR000299
DomainFERM_1

FRMD7 EPB41L1 EPB41L2

2.04e-0350943PS00660
DomainFERM_2

FRMD7 EPB41L1 EPB41L2

2.04e-0350943PS00661
DomainFERM_3

FRMD7 EPB41L1 EPB41L2

2.04e-0350943PS50057
DomainBand_41_domain

FRMD7 EPB41L1 EPB41L2

2.04e-0350943IPR019749
DomainB41

FRMD7 EPB41L1 EPB41L2

2.04e-0350943SM00295
DomainFERM/acyl-CoA-bd_prot_3-hlx

FRMD7 EPB41L1 EPB41L2

2.04e-0350943IPR014352
DomainLdl_recept_b

NID2 LRP2

2.19e-0314942PF00058
DomainLDLRB

NID2 LRP2

2.19e-0314942PS51120
DomainRasGAP

GAPVD1 RASAL3

2.52e-0315942PF00616
DomainRAS_GTPASE_ACTIV_1

GAPVD1 RASAL3

2.52e-0315942PS00509
DomainRAS_GTPASE_ACTIV_2

GAPVD1 RASAL3

2.52e-0315942PS50018
DomainLY

NID2 LRP2

2.52e-0315942SM00135
DomainLDLR_classB_rpt

NID2 LRP2

2.52e-0315942IPR000033
DomainPH

ARHGAP23 PLEKHA6 PLEKHN1 RASAL3 ARHGEF3 ARHGEF2

2.81e-03278946SM00233
DomainPH_DOMAIN

ARHGAP23 PLEKHA6 PLEKHN1 RASAL3 ARHGEF3 ARHGEF2

2.86e-03279946PS50003
Domain-

GAPVD1 RASAL3

2.87e-03169421.10.506.10
DomainPH_domain

ARHGAP23 PLEKHA6 PLEKHN1 RASAL3 ARHGEF3 ARHGEF2

2.91e-03280946IPR001849
DomainTF_T-box

TBX10 TBX6

3.24e-0317942IPR001699
DomainTBOX

TBX10 TBX6

3.24e-0317942SM00425
DomainTF_T-box_CS

TBX10 TBX6

3.24e-0317942IPR018186
Domain-

TBX10 TBX6

3.24e-03179422.60.40.820
DomainTBOX_3

TBX10 TBX6

3.24e-0317942PS50252
DomainT-box

TBX10 TBX6

3.24e-0317942PF00907
DomainTBOX_1

TBX10 TBX6

3.24e-0317942PS01283
DomainTBOX_2

TBX10 TBX6

3.24e-0317942PS01264
DomainRasGAP_dom

GAPVD1 RASAL3

3.64e-0318942IPR001936
DomainDH_1

ARHGEF17 ARHGEF3 ARHGEF2

3.94e-0363943PS00741
DomainRhoGEF

ARHGEF17 ARHGEF3 ARHGEF2

4.88e-0368943SM00325
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

CHD9 N4BP3 ARHGEF17 RUSC2 ZFYVE26 EPB41L1

5.87e-0710410069205841
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

NID2 ARHGAP23 TPRN WWP1 PRSS56 PHRF1 CHD9 TRIM27 PLEKHN1 GADD45GIP1 KIF7 RASAL3 ASPM LRP2 WDTC1

7.10e-0711161001531753913
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

FOXO3 NES GAPVD1 SHROOM3 MATK N4BP3 ARHGEF17 RUSC2 REEP4 ARHGEF2 EPB41L1 EPB41L2 PPP1R12C

1.17e-068611001336931259
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

RBM12B MATK GRN TRIM27 EIF3A PPP1R12C

1.23e-06118100621078624
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FOXO3 FAM193B SHROOM3 EPPK1 SPEG WWP1 KSR2 KIFC2 TMEM129 ZNF335 ZFYVE26 FGFR1 GPC2 ARHGEF2

3.43e-0611051001435748872
Pubmed

Genetic investigation of FOXO3A requires special attention due to sequence homology with FOXO3B.

FOXO3 FOXO3B

8.18e-062100222588664
Pubmed

Molecular cloning of FKHRL1P2, a member of the developmentally regulated fork head domain transcription factor family.

FOXO3 FOXO3B

8.18e-06210029852958
Pubmed

Genetic and functional analysis of SHROOM1-4 in a Chinese neural tube defect cohort.

SHROOM3 SHROOM2

8.18e-062100229423651
Pubmed

Expression profiling of metalloproteinases and their inhibitors in cartilage.

ADAMTS2 MMP28

8.18e-062100214730609
Pubmed

Two mammalian MAGOH genes contribute to exon junction complex composition and nonsense-mediated decay.

MAGOH MAGOHB

8.18e-062100223917022
Pubmed

The function of glutamatergic synapses is not perturbed by severe knockdown of 4.1N and 4.1G expression.

EPB41L1 EPB41L2

8.18e-062100219225127
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

FOXO3 GAPVD1 MAGOH MAGOHB N4BP3 SHROOM2 ARHGEF2

9.40e-06255100715324660
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

NES GAK ARHGAP23 MAP6 PLEKHA6 ARHGEF17 SHROOM2 NRXN2 PRICKLE2 EIF3A ARHGEF2 PRRC2A EPB41L1 EPB41L2 PPP1R12C

1.44e-0514311001537142655
Pubmed

Regulation of AMPA receptor GluR1 subunit surface expression by a 4. 1N-linked actin cytoskeletal association.

EPB41L1 EPB41L2

2.45e-053100211050113
Pubmed

A splice junction-targeted CRISPR approach (spJCRISPR) reveals human FOXO3B to be a protein-coding gene.

FOXO3 FOXO3B

2.45e-053100229925039
Pubmed

Developmental signals control chromosome segregation fidelity during pluripotency and neurogenesis by modulating replicative stress.

NES FGFR1

2.45e-053100239191776
Pubmed

CCDC88B interacts with RASAL3 and ARHGEF2 and regulates dendritic cell function in neuroinflammation and colitis.

RASAL3 ARHGEF2

2.45e-053100238200184
Pubmed

Assembly, disassembly and recycling: the dynamics of exon junction complexes.

MAGOH MAGOHB

2.45e-053100221289489
Pubmed

MAGOH and MAGOHB Knockdown in Melanoma Cells Decreases Nonsense-Mediated Decay Activity and Promotes Apoptosis via Upregulation of GADD45A.

MAGOH MAGOHB

2.45e-053100236497117
Pubmed

PTPN23 binds the dynein adaptor BICD1 and is required for endocytic sorting of neurotrophin receptors.

NES GRN ARHGEF2

2.54e-0520100332079660
Pubmed

BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A.

GAK HIRIP3 LRRC10 MAGOHB GADD45GIP1 ARHGEF2 NLRC3 PPP1R12C

2.94e-05419100833001583
Pubmed

Foxo4- and Stat3-dependent IL-10 production by progranulin in regulatory T cells restrains inflammatory arthritis.

FOXO3 GRN

4.89e-054100228011648
Pubmed

Cardiac muscle cell cytoskeletal protein 4.1: analysis of transcripts and subcellular location--relevance to membrane integrity, microstructure, and possible role in heart failure.

EPB41L1 EPB41L2

4.89e-054100215834631
Pubmed

Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily.

FOXO3 FOXO3B

4.89e-05410029479491
Pubmed

A new standard nomenclature for proteins related to Apx and Shroom.

SHROOM3 SHROOM2

4.89e-054100216615870
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

SPEG PLEKHA6 PRICKLE2 PRRC2A EPB41L1 EPB41L2

5.70e-05231100616452087
Pubmed

Megalin deficiency induces critical changes in mouse spinal cord development.

NES LRP2

8.14e-055100218388738
Pubmed

Expression of Epiplakin1 in the developing and adult mouse retina.

NES EPPK1

8.14e-055100220151282
Pubmed

Components of the CCR4-NOT complex function as nuclear hormone receptor coactivators via association with the NRC-interacting Factor NIF-1.

CNOT6 ZNF335

8.14e-055100218180299
Pubmed

Band 4.1 proteins regulate integrin-dependent cell spreading.

EPB41L1 EPB41L2

8.14e-055100222982319
Pubmed

The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.

MAGOH MAGOHB

8.14e-055100211532962
Pubmed

14-3-3 Integrates prosurvival signals mediated by the AKT and MAPK pathways in ZNF198-FGFR1-transformed hematopoietic cells.

FOXO3 FGFR1

1.22e-046100217389761
Pubmed

Human major histocompatibility complex contains a minimum of 19 genes between the complement cluster and HLA-B.

PRRC2A GPANK1

1.22e-04610022813433
Pubmed

Low-density lipoprotein receptor-related protein (LRP)-2/megalin is transiently expressed in a subpopulation of neural progenitors in the embryonic mouse spinal cord.

NES LRP2

1.70e-047100216196028
Pubmed

Localization of the casein kinase II beta-subunit gene within the mouse H-2 complex class III region and comparison of expression with Bat genes.

PRRC2A GPANK1

1.70e-04710029196000
Pubmed

D2 and D3 dopamine receptor cell surface localization mediated by interaction with protein 4.1N.

EPB41L1 EPB41L2

1.70e-047100212181426
Pubmed

Mutation of ARHGAP9 in patients with coronary spastic angina.

ARHGEF17 ARHGEF3 ARHGEF2

1.81e-0438100319911011
Pubmed

Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.

ARHGEF17 ARHGEF3 ARHGEF2

1.81e-0438100311756498
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

WWP1 GRN N4BP3 TRIM27 KIF7 RUSC2 EIF3A PPP1R12C

2.19e-04560100821653829
Pubmed

Progranulin expression in the developing and adult murine brain.

NES GRN

2.27e-048100220737593
Pubmed

Rab22B is expressed in the CNS astroglia lineage and plays a role in epidermal growth factor receptor trafficking in A431 cells.

NES GAPVD1

2.27e-048100219725050
Pubmed

FGF10 promotes regional foetal cardiomyocyte proliferation and adult cardiomyocyte cell-cycle re-entry.

FOXO3 FGFR1

2.27e-048100225344367
Pubmed

Structural diversity of band 4.1 superfamily members.

EPB41L1 EPB41L2

2.27e-04810027983158
Pubmed

FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak.

FGFR1 TBX6

2.27e-048100211703922
Pubmed

PFGE mapping and RFLP analysis of the S/D region of the mouse H-2 complex.

PRRC2A GPANK1

2.27e-04810021351875
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

GAPVD1 SHROOM3 ARHGAP23 PHRF1

2.29e-04103100410819331
Pubmed

NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway.

ARHGEF17 ARHGEF3 ARHGEF2

2.62e-0443100312376548
Pubmed

LDL receptor-related protein as a component of the midkine receptor.

NID2 LRP2

2.91e-049100210772929
Pubmed

Ectopic expression of Gcm1 induces congenital spinal cord abnormalities.

FGFR1 TBX6

2.91e-049100212135932
Pubmed

Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions.

SHROOM3 SHROOM2

2.91e-049100217666436
Pubmed

USP40 deubiquitinates HINT1 and stabilizes p53 in podocyte damage.

NES LRP2 EPB41L1

3.00e-0445100335605301
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

FOXO3 GAPVD1 SHROOM3 TRIM27 KIF7 REEP4 ARHGEF2

3.13e-04446100724255178
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SHROOM3 MAGOH PHRF1 N4BP3 TRIM27 CNOT6 EIF3A REEP4 ARHGEF2 PRRC2A EPB41L1 EPB41L2 PPP1R12C

3.61e-0414971001331527615
Pubmed

Association between genetic variants of reported candidate genes or regions and risk of cleft lip with or without cleft palate in the polish population.

TBX10 FGFR1

3.63e-0410100220544801
Pubmed

Glypicans are differentially expressed during patterning and neurogenesis of early mouse brain.

FGFR1 GPC2

3.63e-0410100217107664
Pubmed

Ablation of cholesterol biosynthesis in neural stem cells increases their VEGF expression and angiogenesis but causes neuron apoptosis.

NES LRP2

4.43e-0411100219416849
Pubmed

A Smaug2-Based Translational Repression Complex Determines the Balance between Precursor Maintenance versus Differentiation during Mammalian Neurogenesis.

NES NANOS1

4.43e-0411100226609159
Pubmed

Overexpression of translocation-associated fusion genes of FGFRI, MYC, NPMI, and DEK, but absence of the translocations in acute myeloid leukemia. A microarray analysis.

GRN FGFR1

4.43e-0411100212031912
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NES SHROOM3 MAP6 KSR2 DDN KIF7 ARHGEF2 PRRC2A EPB41L1 EPB41L2

4.62e-049631001028671696
Pubmed

The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.

GAPVD1 WWP1 MYG1 EPB41L1 EPB41L2

4.95e-04225100525277244
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

PLEKHA6 RUSC2 PRICKLE2 ARHGEF2 PRRC2A EPB41L1

5.12e-04347100617114649
Pubmed

P1 and cosmid clones define the organization of 280 kb of the mouse H-2 complex containing the Cps-1 and Hsp70 loci.

PRRC2A GPANK1

5.30e-041210027993390
Pubmed

Variant heparan sulfates synthesized in developing mouse brain differentially regulate FGF signaling.

FGFR1 HS6ST3

5.30e-0412100212460940
Pubmed

Paracrine action of FGF4 during periimplantation development maintains trophectoderm and primitive endoderm.

FGFR1 TBX6

5.30e-0412100212748966
Pubmed

Fine mapping of the MHC Class III region demonstrates association of AIF1 and rheumatoid arthritis.

PRRC2A GPANK1

5.30e-0412100218835879
Pubmed

The initiation and propagation of Hes7 oscillation are cooperatively regulated by Fgf and notch signaling in the somite segmentation clock.

FGFR1 TBX6

6.25e-0413100217681139
Pubmed

Loss of Aspm causes increased apoptosis of developing neural cells during mouse cerebral corticogenesis.

NES ASPM

6.25e-0413100238019816
Pubmed

Global phosphoproteome of HT-29 human colon adenocarcinoma cells.

EPPK1 HIRIP3 PRRC2A

6.67e-0459100316083285
Pubmed

Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR).

ARHGEF17 ARHGEF3 ARHGEF2

7.01e-0460100312787561
Pubmed

Ischemic stroke is associated with the ABO locus: the EuroCLOT study.

F3 ASPM

7.28e-0414100223381943
Pubmed

A mechanism for gene-environment interaction in the etiology of congenital scoliosis.

FGFR1 TBX6

7.28e-0414100222484060
Pubmed

A physical map of the mouse H2 Bat5/Db interval.

PRRC2A GPANK1

7.28e-041410029021146
Pubmed

FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis.

FOXO3 ASPM

7.28e-0414100219896444
Pubmed

Commissural neurons transgress the CNS/PNS boundary in absence of ventricular zone-derived netrin 1.

NES PRSS56

7.28e-0414100229343638
Pubmed

FGF signaling through FGFR1 is required for olfactory bulb morphogenesis.

NES FGFR1

7.28e-0414100212571102
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

NES GAPVD1 EPPK1 RBM12B GRN GADD45GIP1 KIF7 EIF3A ARHGEF2 EPB41L2

7.42e-0410241001024711643
Pubmed

PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.

GAPVD1 RBM12B TRIM27 GADD45GIP1 ASPM

7.55e-04247100532989298
Pubmed

Neural defects caused by total and Wnt1-Cre mediated ablation of p120ctn in mice.

NES SHROOM3

8.39e-0415100232741376
Pubmed

FAM188B enhances cell survival via interaction with USP7.

KIF7 EIF3A MINDY4

8.85e-0465100329795372
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

SHROOM3 CNOT6 FGFR1 ARHGEF2 PRRC2A EPB41L1 EPB41L2

9.25e-04536100715840001
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

SHROOM3 CNOT6 FGFR1 ARHGEF2 PRRC2A EPB41L1 EPB41L2

9.46e-04538100710512203
Pubmed

Fibroblast growth factor receptor 1 is required for the proliferation of hippocampal progenitor cells and for hippocampal growth in mouse.

NES FGFR1

9.57e-0416100215240797
Pubmed

Astroglial-Mediated Remodeling of the Interhemispheric Midline Is Required for the Formation of the Corpus Callosum.

NES FGFR1

9.57e-0416100227732850
Pubmed

Excitatory neuronal CHD8 in the regulation of neocortical development and sensory-motor behaviors.

NES MAP6

9.57e-0416100233626347
Pubmed

Growth/differentiation factor 15 promotes EGFR signalling, and regulates proliferation and migration in the hippocampus of neonatal and young adult mice.

NES FGFR1

9.57e-0416100224496615
Pubmed

Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice.

NES SHROOM3

9.57e-0416100215037549
Pubmed

A comprehensive family-based replication study of schizophrenia genes.

POM121L2 PRRC2A

1.08e-0317100223894747
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

SHROOM3 LRP2 ARHGEF3

1.14e-0371100333541421
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SPEG DDN CAMTA2 ARHGEF17 RUSC2 EPB41L1

1.17e-03407100612693553
Pubmed

Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain.

ARHGEF3 ARHGEF2

1.22e-0318100212799088
Pubmed

Midline radial glia translocation and corpus callosum formation require FGF signaling.

NES FGFR1

1.22e-0318100216715082
Pubmed

A beta-catenin gradient links the clock and wavefront systems in mouse embryo segmentation.

FGFR1 TBX6

1.22e-0318100218157121
Pubmed

Maternal hyperglycemia activates an ASK1-FoxO3a-caspase 8 pathway that leads to embryonic neural tube defects.

FOXO3 NES

1.22e-0318100223982205
Pubmed

A protein-RNA interaction atlas of the ribosome biogenesis factor AATF.

PHRF1 MAGOHB EIF3A PRRC2A

1.26e-03162100431363146
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

GAPVD1 GAK MAGOH HIRIP3 ARHGAP23 MAGOHB RTL1 FGFR1 ARHGEF2

1.26e-03910100936736316
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

GAPVD1 GRN ZNF831 ARHGEF17 PRICKLE2 LRP2 EIF3A EPB41L2

1.30e-03736100829676528
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

NES EPPK1 ARHGAP23 TRIM27 ARHGEF17 ARHGEF3 ARHGEF2 PRRC2A EPB41L2

1.32e-03916100932203420
Pubmed

Genetic mapping and physical cloning of UVB susceptibility region in mice.

PRRC2A GPANK1

1.36e-0319100210469308
Pubmed

Genomewide association study of an AIDS-nonprogression cohort emphasizes the role played by HLA genes (ANRS Genomewide Association Study 02).

PRRC2A GPANK1

1.36e-0319100219115949
Pubmed

α5β1 integrin-mediated adhesion to fibronectin is required for axis elongation and somitogenesis in mice.

FGFR1 TBX6

1.36e-0319100221799763
GeneFamilyErythrocyte membrane protein band 4.1|FERM domain containing

EPB41L1 EPB41L2

6.47e-054602951
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

FRMD7 EPB41L1 EPB41L2

6.09e-04506031293
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF17 ARHGEF3 ARHGEF2

1.37e-0366603722
GeneFamilyT-boxes

TBX10 TBX6

1.60e-0318602766
ToppCellNS-critical-d_0-4-Epithelial-unknown_epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NUDT19 EPPK1 PLEKHA6 N4BP3 PLEKHN1 MINDY4 ARHGEF3

9.84e-081661007dd02bbe4af609c6348dc92417254f4740f2900a8
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SHROOM3 ADAMTS2 ARHGEF17 F3 KIFC2 KIF7 FGFR1

1.98e-071841007e33e2a887aafba7b6a31f00bb0dbe974b4359fd6
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4|TCGA-Prostate / Sample_Type by Project: Shred V9

TRABD2B ARHGAP23 ARHGEF17 RUSC2 LIPE FGFR1 ARHGEF2

2.94e-0719510075562665dd3beb70e2358aa32611a337bef5731c1
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES ARHGAP23 SPEG DDN PAPOLB PRICKLE2

2.29e-06169100687116c33c5ca8cb1862e103e5607b1df4d264569
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NES ARHGAP23 MAP6 DDN F3 HS3ST3A1

2.53e-0617210066c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

CAMTA2 TRIM27 TMEM129 SPACA6 PRRC2A NLRC3

3.29e-06180100681d60f0fa9e3b5bfcec85139a0a49e9130145f0e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NES MAP6 DDN F3 ARHGEF3 HS3ST3A1

3.62e-061831006612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NES ARHGAP23 MAP6 DDN F3 HS3ST3A1

3.62e-061831006848fc6dd129150897ee339343e83c645b6e779eb
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NES ARHGAP23 MAP6 DDN F3 HS3ST3A1

3.85e-0618510069197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NES ARHGAP23 MAP6 DDN F3 HS3ST3A1

3.85e-061851006ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NES ARHGAP23 MAP6 DDN F3 HS3ST3A1

3.85e-061851006b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NES SHC2 PRICKLE2 ARHGEF3 HYAL2 EPB41L2

4.49e-0619010060e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

NES N4BP3 SHC2 PRICKLE2 ARHGEF3 EPB41L2

4.63e-061911006f229abf69a1217194f74b0502486907e07dba989
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NES ARHGAP23 MAP6 DDN F3

3.87e-051681005fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-regulatory_T_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MATK TEX22 RASAL3 ZC3H12D HS6ST3

3.87e-0516810052d2eab3190374f79f373e31c8b062ff4e1766396
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MATK TEX22 RASAL3 ZC3H12D HS6ST3

3.87e-051681005df58156721457b34af1e81c0eb8a7243cbbfb303
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NES ARHGAP23 MAP6 DDN F3

3.87e-051681005315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP23 MAP6 DDN F3 ARHGEF3

3.87e-051681005e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122|Adult / Lineage, Cell type, age group and donor

SHROOM2 SHC2 PRICKLE2 HYAL2 EPB41L2

4.21e-051711005bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-regulatory_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATK RASAL3 ZC3H12D SPACA6 REEP4

4.32e-05172100510a1d1838492b8ce6dea08844353b51571432c56
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MATK RASAL3 ZC3H12D SPACA6 REEP4

4.32e-051721005d824e46c8040b0bb9235f9b8a2b35386b303caa0
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES DDN JSRP1 PRICKLE2 HS3ST3A1

4.32e-051721005073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NES MAP6 DDN F3 HS3ST3A1

4.32e-051721005381ae1c3c07d0a424f43455ec571653b192a946a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NES MAP6 DDN F3 HS3ST3A1

4.57e-051741005dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

TRABD2B SHROOM3 PLEKHA6 LRP2 EPB41L1

4.82e-05176100536f77d878a53b30465b0dea8333a3865dba75613
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGEF17 PRICKLE2 FGFR1 HS3ST3A1 EPB41L2

4.96e-051771005bd602db857f37869ef76d14c05ef522c509f08ee
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NES MAP6 DDN F3 HS3ST3A1

4.96e-0517710054d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NES MAP6 DDN F3 HS3ST3A1

5.09e-051781005edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCellfacs-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 MAP6 DDN ARHGEF17 NANOS1

5.23e-0517910057078022e60faa86444f2a2c6eb9f767cc66b5cfa
ToppCellfacs-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 MAP6 DDN ARHGEF17 NANOS1

5.23e-051791005d4a975d8ffa5e77fb5c0ec05bf9c8f843c77ce07
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 SHROOM3 MAP6 FJX1 ARHGEF17

5.66e-0518210059edaccf1154cec92ca9a28e9b1f9075cfd422bfd
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 SHROOM3 MAP6 FJX1 ARHGEF17

5.66e-051821005aba4c06d5d7618ac21b2695bca8e7a1346a91090
ToppCellCOVID-19-kidney-Podocyte|kidney / Disease (COVID-19 only), tissue and cell type

NES MAP6 DDN F3 HS3ST3A1

5.80e-051831005fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP6 DDN F3 ARHGEF3 HS3ST3A1

5.80e-051831005eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCelldroplet-Lung-1m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NID2 SHROOM3 MAP6 FJX1 ARHGEF17

5.96e-0518410054cb5f299dd7413e0be1ad7af817ee614b23a18ae
ToppCelldroplet-Lung-1m-Mesenchymal-myofibroblast-pericyte_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NID2 SHROOM3 MAP6 FJX1 ARHGEF17

5.96e-05184100539bb0eb55bdc2cea46e41c7f21d8c5883f14e6bd
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS2 ARHGEF17 KIF7 RUSC2 PRICKLE2

6.11e-0518510059faa35ceb89ccd2979072286f063687c9f846ce3
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FRMD7 PLEKHA6 F3 SHC2 FGFR1

6.11e-0518510051b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCellControl-Endothelial-VE_Capillary_A|Control / Disease state, Lineage and Cell class

NES SHROOM2 PRICKLE2 HYAL2 EPB41L2

6.43e-05187100554d7588172ac145ff5045ad9771636729ca3f0ca
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|343B / Donor, Lineage, Cell class and subclass (all cells)

NES N4BP3 PRICKLE2 HYAL2 INKA1

6.59e-051881005fe7143c36e4a883745862d3c3147cf751b440e46
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|343B / Donor, Lineage, Cell class and subclass (all cells)

NES N4BP3 PRICKLE2 HYAL2 INKA1

6.59e-051881005cbf32b675a7cd0c808d5c9c22dfa7fa79fbe2437
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NES SHROOM2 PRICKLE2 HYAL2 EPB41L2

6.76e-051891005b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCellIPF-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

NES N4BP3 SHROOM2 PRICKLE2 HYAL2

6.76e-051891005ea3aa3ef38f1d405bb527ae383cd12c551a3dd6f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FOXO3 ADAMTS2 KIF7 FGFR1 EPB41L2

6.93e-0519010051121eb607a984c59fbffe7220837fc178745aa55
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES NID2 FJX1 ARHGEF17 EPB41L2

6.93e-0519010057e4d80a3a7f83b6a50f1d0fe82fb6c242c39d5b0
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES MAP6 FJX1 ARHGEF17 EPB41L2

6.93e-0519010051004e89d99c9d46c78b7d3532d8d4aadb81a96fd
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FOXO3 ADAMTS2 KIF7 FGFR1 EPB41L2

6.93e-051901005048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellIPF-Endothelial-VE_Capillary_A|IPF / Disease state, Lineage and Cell class

NES N4BP3 SHROOM2 PRICKLE2 HYAL2

6.93e-051901005b4e35cbfe4d43d2cd51f29c3085e4d9b1012e6f0
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES GAPVD1 ADAMTS2 EIF3A EPB41L2

6.93e-051901005d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES NID2 FJX1 ARHGEF17 EPB41L2

6.93e-0519010057fec459cd2ad12c2923a03d098289337c0a4c1d3
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES MAP6 FJX1 ARHGEF17 EPB41L2

6.93e-05190100510b02c62e72bfea9767e3e751011436925da823e
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NID2 ADAMTS2 FJX1 PLEKHA6 NRXN2

6.93e-0519010054f775ee24b14733f06ae40b45f2dc1a0f0df0705
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NES NID2 FJX1 ARHGEF17 EPB41L2

6.93e-05190100584fbd5664ec886120963d4f50dfa1fd1851d36c1
ToppCellfacs-Heart-LV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS2 PLEKHA6 ARHGEF17 FGFR1 EPB41L1

7.11e-051911005b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NES MAP6 DDN F3 ARHGEF3

7.28e-051921005ef0aba777072429a6ab7dcfcc305673975946580
ToppCellEndothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|World / Lineage, Cell type, age group and donor

NES N4BP3 SHC2 PRICKLE2 EPB41L2

7.28e-0519210051e156bab5ecf64627890d2de9b27603d9a01f28d
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NES SHROOM2 PRICKLE2 HYAL2 EPB41L2

7.46e-051931005f582e939e3e08a8a3f71deec78c33715be8faa51
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NES MAP6 DDN F3 ARHGEF3

7.46e-0519310053eaa0461618582a1754400624350d269d24e750a
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRABD2B ADAMTS2 F3 SHC2 FGFR1

7.46e-051931005fe9720185929ef849edd1b8eb4854306b392e5a2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRABD2B SHROOM3 PLEKHA6 LRP2 EPB41L1

7.46e-0519310053866667dd221612589ae50f5c52f73a183a49ce6
ToppCellChildren_(3_yrs)-Immune-natural_killer_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

MATK ZNF831 RASAL3 ARHGEF3 NLRC3

7.46e-0519310051cb666375bc4e1b11a146d20896c9b5ae6fd0887
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRABD2B ADAMTS2 F3 SHC2 FGFR1

7.65e-0519410055594f7437448cb4b37d2d100f44d30c4a367df26
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRABD2B SHROOM3 PLEKHA6 LRP2 EPB41L1

7.65e-0519410057002937e8903e037332a215d00fbc7c7843b33f2
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES NID2 FJX1 ARHGEF17 NRXN2

7.83e-0519510054a5d2f62aad5817d077177bf8b4ff0e46d3b8d97
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES NID2 FJX1 ARHGEF17 NRXN2

7.83e-0519510057a32a8535c29b819dacba901d0658280a2631c94
ToppCellCOVID-19-lung-Capillary_Aerocytes|COVID-19 / Disease (COVID-19 only), tissue and cell type

N4BP3 SHROOM2 SHC2 PRICKLE2 EPB41L2

8.03e-05196100549cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCellCOVID-19-lung-Capillary_Aerocytes|lung / Disease (COVID-19 only), tissue and cell type

N4BP3 SHROOM2 SHC2 PRICKLE2 EPB41L2

8.03e-0519610054ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCellHealthy_Control-Lymphoid|Healthy_Control / Condition, Lineage, Cell class and cell subclass

MATK ZNF831 RASAL3 ASPM NLRC3

8.42e-051981005c176c583f426e4373daca4a696ab8832e838cfbf
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 TRABD2B ADAMTS2 MMP28 HS3ST3A1

8.42e-0519810058b9e8eaeffda40912a0163fdf39b93bc5e64751c
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NES N4BP3 SHC2 PRICKLE2 EPB41L2

8.62e-051991005dc88ce36cc066eb6c28cfd5b9b60fe07f8cc7b53
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MATK KLHDC7B RASAL3 SPACA6 ARHGEF3

8.62e-05199100526bb93347e6722abd174dfa62cab692ce2b7eb23
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NES N4BP3 ARHGEF3 HYAL2 INKA1

8.83e-052001005bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRABD2B ADAMTS2 FGFR1 HS3ST3A1 EPB41L2

8.83e-052001005389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NES N4BP3 ARHGEF3 HYAL2 INKA1

8.83e-052001005b7533c571eeea0cb3678e1a57d3dc036fa8d0f49
ToppCellLPS-IL1RA-Endothelial-Epi-like-Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NES LRP2 HS6ST3 GPANK1

2.64e-0413810045f8ac8f67e34a7cf560099208e6884102532391e
ToppCellTCGA-Bladder|World / Sample_Type by Project: Shred V9

ARHGAP23 KLHDC7B PLEKHN1 TBX6

2.95e-04142100458d1fdc5ec4e5bf307b7a502c081a8a84d7560cd
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-Tfh|Lung / Manually curated celltypes from each tissue

EPPK1 KSR2 ZNF831 LRP2

2.95e-041421004319812c84fad93276bf093f2ad78db02ae745bf4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_low-phase|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG KIF7 TEX22 ASPM

3.11e-041441004f6061dd965a2b2fe6ad864f8aecc06d2e74881ce
ToppCellNS-critical-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIF7 TEX22 ASPM GPC2

3.11e-0414410040fde5cd82df9b90aefde19275cff6c2ec3c9d5cb
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|368C / Donor, Lineage, Cell class and subclass (all cells)

JSRP1 ZC3H12D ASPM NLRC3

3.45e-04148100480470353e12599440f711b6e107730763376d04d
ToppCellLPS_only-Hematopoietic_Mast-Mast_cells-T-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MATK ZNF831 RASAL3 NLRC3

3.63e-041501004ccb782fbcb3122266354a112a9a850506664f44d
ToppCellPND01-03-samps-Epithelial-Alveolar_epithelial-AT1_-_meso|PND01-03-samps / Age Group, Lineage, Cell class and subclass

EPPK1 MAP6 F3 RUSC2

3.63e-0415010046a13e4c4b9c9e54a5016573a37132465ec1c8f99
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Mast-Mast_cells-T-cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MATK PRSS56 RASAL3 NLRC3

3.72e-041511004b85a763459a0f019d1f9975d09b9f2247d62c9d3
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related-Oligodendrocyte/OPC|GW10 / Sample Type, Dataset, Time_group, and Cell type.

NID2 SHFL TEX22 HS3ST3A1

3.72e-0415110044533bccc996395f74b16af939ce79b6fe253c073
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related|GW10 / Sample Type, Dataset, Time_group, and Cell type.

NID2 SHFL TEX22 HS3ST3A1

3.72e-041511004edb2f59789c295838d2030b80c792cbea25eaa3d
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TRABD2B SPEG KIF7 HS3ST3A1

3.91e-0415310041524557514668f515ac1bbe847611f564b265b42
ToppCell10x5'-bone_marrow-Lymphocytic_B-Pro-B|bone_marrow / Manually curated celltypes from each tissue

NID2 FJX1 NRXN2 GPC2

4.01e-0415410048a8c3851888ab86ca2b13ccc042cde1fef8d88f8
ToppCell(6)_Endothelial_cells-(6)_Endothelial-C_(Capillary_Aerocyte_)|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

SHROOM3 MATK N4BP3 PRICKLE2

4.31e-04157100484f629b7f589ca8a1abc220fa740c4a6fdc1b579
ToppCelldroplet-Liver-Hepatocytes-24m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF831 RASAL3 GPC2 GPANK1

4.31e-041571004cbb08d5c151f0622123276926a2a15bb7d271e90
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXO3 MATK CC2D2A GPC2

4.31e-041571004d8e283414a770f05d71f0455d0822e9a9660b115
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXO3 MATK CC2D2A GPC2

4.31e-041571004165e98bf944572cafbc06ef43c9eab7bd6bea1c2
ToppCelldroplet-Liver-Hepatocytes-24m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF831 RASAL3 GPC2 GPANK1

4.31e-04157100416581e2399a211633f870dce326c75ff4b6a5fe6
ToppCellBasal_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

FJX1 KIF7 LIPE INKA1

4.42e-04158100451e3ed1b91b010404d66e3e7efdbffc0c815e25b
ToppCellControl-Endothelial_cells-Inflamed_endothelial_cells|Control / group, cell type (main and fine annotations)

NES PRICKLE2 HYAL2 EPB41L2

4.63e-041601004958256e3d3836160763b82bb48f794087918d935
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MATK COLGALT1 SHC2 ARHGEF3

4.63e-0416010046d941e584360975e1fdbb2fc67af8e31f18759d8
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAP6 F3 HS6ST3 EPB41L1

4.97e-04163100456b8668dbf06faa6866ec71f29b92907b73f074d
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tfh|GI_large-bowel / Manually curated celltypes from each tissue

MMP28 KSR2 FGFR1 NANOS1

4.97e-0416310044104d3b9748b39cb0744c9be76db21bdda566a0d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF17 KIF7 HS3ST3A1 EPB41L2

5.08e-041641004b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCellT_cells-TFH-like_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

KSR2 ZNF831 ZC3H12D FGFR1

5.08e-041641004b10cf59f4cc37ca6cd0ecf71d7de278cc2bdd8b5
ToppCelldroplet-Lung-nan-3m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTCRA MAP6 PAPOLB PLEKHN1

5.08e-04164100478de403446fe0eb375c82ff1832cc5fbb8e20afa
Diseasedermoid cyst of ovary (implicated_via_orthology)

FOXO3 FOXO3B

1.07e-052972DOID:5117 (implicated_via_orthology)
Diseaseregulator of microtubule dynamics protein 1 measurement

WWP1 ARHGEF3

1.06e-045972EFO_0801998
Diseaseprocollagen galactosyltransferase 1 measurement

COLGALT1 ARHGEF3

2.96e-048972EFO_0801922
Diseasecreativity measurement

HS6ST3 EPB41L2

4.73e-0410972EFO_0010650
Diseasecleft lip (is_implicated_in)

KIF7 FGFR1

1.09e-0315972DOID:9296 (is_implicated_in)
DiseaseAutosomal recessive primary microcephaly

ZNF335 ASPM

1.09e-0315972cv:C3711387
Diseaseurolithiasis

SHROOM3 MINDY4 EPB41L2

1.19e-0363973MONDO_0024647
Diseaseparental longevity

GAPVD1 SHROOM3 SHFL KSR2 PRICKLE2 HS6ST3 GPANK1

1.24e-03494977EFO_0007796
Diseasevision disorder

TRABD2B F3

1.25e-0316972MONDO_0021084
Diseasetransferrin saturation measurement

DUOX2 F3

1.25e-0316972EFO_0006333
DiseaseSclerocystic Ovaries

ARHGAP23 PTCRA JSRP1 ASPM

1.33e-03144974C1136382
DiseasePolycystic Ovary Syndrome

ARHGAP23 PTCRA JSRP1 ASPM

1.33e-03144974C0032460
Diseaseobesity (biomarker_via_orthology)

FOXO3 FOXO3B LIPE FGFR1

1.43e-03147974DOID:9970 (biomarker_via_orthology)
Diseasecreatinine measurement

NUDT19 FOXO3 GAPVD1 SHROOM3 SPEG FRMD7 CHD9 NRXN2 LRP2 NLRC3

1.62e-039959710EFO_0004518
Diseasehemifacial microsomia

NID2 SHROOM3

1.76e-0319972MONDO_0015398
Diseasecoagulation factor measurement

F3 ASPM

1.96e-0320972EFO_0004634
DiseaseFamilial aplasia of the vermis

KIF7 CC2D2A

1.96e-0320972cv:C0431399
Diseasetotal iron binding capacity

DUOX2 POM121L2 F3

2.19e-0378973EFO_0006334
Diseasenephrosis (biomarker_via_orthology)

NES LRP2

2.37e-0322972DOID:2527 (biomarker_via_orthology)
Diseaseinflammatory bowel disease (implicated_via_orthology)

EPB41L1 EPB41L2

3.05e-0325972DOID:0050589 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
ESRPDILAPRPWSRN

ARHGEF3

76

Q9NR81
AEAPWARRPVDPRRR

ARHGEF2

871

Q92974
EAPRWDAPLRDPALR

GRN

576

P28799
CPLLPPERLRWNTNE

CAMTA2

31

O94983
PPRRPWASRVLQEAT

DDN

81

O94850
WEVSPTERRPPAGLR

ASPM

11

Q8IZT6
VVQWLSRPDPDSPIR

ADAMTS2

1041

O95450
RRPWEEDFRRPPEDD

RBM12B

596

Q8IXT5
DWRRPLEEDFRRSPT

RBM12B

626

Q8IXT5
DFRRPPEEDWRRPPE

RBM12B

666

Q8IXT5
PEEDWRRPPEEDFRR

RBM12B

671

Q8IXT5
WRRPPEDDFRRPPEE

RBM12B

691

Q8IXT5
SWARPRPDEERPLRR

RASAL3

796

Q86YV0
AAWEPPARESRQPPT

ARHGEF17

156

Q96PE2
LNLPVWDPRVNPSDR

PAPOLB

296

Q9NRJ5
DWERERRLPSSPASP

EPB41L1

531

Q9H4G0
WREEELPVSQRPAPS

INKA1

106

Q96EL1
EATSSPRPQPRDRRW

PTCRA

206

Q6ISU1
RQLVASRHPDWPPDR

HYAL2

156

Q12891
RRRTAWNPLGEAAPP

HIRIP3

506

Q9BW71
WEAEPARRPPFRKLA

MATK

461

P42679
RAWKVQRPEPSCRPR

MAP6

126

Q96JE9
REPREALPQRWESRE

JSRP1

271

Q96MG2
WVSPRRPDEEQRPGS

JSRP1

306

Q96MG2
RTGPQDAELWPPRTL

NLRC3

346

Q7RTR2
ERPPRVATLSWREER

GPANK1

321

O95872
PPGLASWRDRVRQDP

NUDT19

161

A8MXV4
NRRAPPPREEAGRLW

GPC2

356

Q8N158
RLPLPEPWRGLRDEA

MYG1

316

Q9HB07
LWPPPDRVGRQELEI

MAGOH

76

P61326
PRWSPQIPRRDLGNS

KSR2

396

Q6VAB6
PRWSPIRAEERTSPH

FRMD7

506

Q6ZUT3
PSWNRRPGNEERELP

GAPVD1

916

Q14C86
RWDPETGRSPSNPRD

DUOX2

156

Q9NRD8
EPRPNEWEKRRITPL

EPB41L2

661

O43491
PREERAPAWAAEPRL

NANOS1

181

Q8WY41
NRATVNWRPEAERPP

KIF7

351

Q2M1P5
RLRRPSPPEPWDEED

PHRF1

931

Q9P1Y6
SRDPWEPPREGREES

NES

1161

P48681
WRRRRPPAPRDDGEE

HS3ST3A1

96

Q9Y663
RVGRWAEETPEPDPR

LRRC10

236

Q5BKY1
VNDRPPDRRCIPQSW

LRP2

2956

P98164
RQESPWRSPGQRARP

POM121L12

146

Q8N7R1
PRRVQRRAWPPDKEQ

TK2

31

O00142
RRAQAPPEEWERRPQ

HS6ST3

56

Q8IZP7
PTQRPPTICERWREN

NID2

1011

Q14112
WPPNDRPSTRMDRLA

NRXN2

106

P58401
PSLNRDPIWRSREEP

PRICKLE2

386

Q7Z3G6
PRWHVSARQPRPEES

FJX1

101

Q86VR8
PRDRPSREAPPWENS

GAK

711

O14976
SRPRSCTWPLQRPEL

FOXO3B

111

A0A2Z4LIS9
RPDTRRLDRPPSNIW

CHD9

831

Q3L8U1
ERAAQSRRRPWEPTL

CC2D2A

636

Q9P2K1
SRRRPWEPTLVPELS

CC2D2A

641

Q9P2K1
RPSWRNTDDDRPPRR

EIF3A

986

Q14152
PPRESRPSEEREWDR

EIF3A

1191

Q14152
SREPRPARERLLEWP

FAM193B

526

Q96PV7
PEDPRWELPRDRLVL

FGFR1

466

P11362
DPEDLLTPRWQLGPR

GADD45GIP1

41

Q8TAE8
TWRPLTQVPEEAPLR

KLHDC7B

331

Q96G42
ERWSPESPLQAPRVL

COLGALT1

41

Q8NBJ5
APRDAELIEPWRPSL

SPACA6

266

W5XKT8
AESPLPPGEWELRRA

INAVA

526

Q3KP66
PRSWIMLQEPDRTRP

CNOT6

171

Q9ULM6
RRRPDLPAPELWTEL

KIFC2

41

Q96AC6
LELWPRPQQAPRSRS

LIPE

631

Q05469
SREPSCRELLAWDPP

PRSS56

341

P0CW18
WSDTEAVPRAPARPR

REEP4

201

Q9H6H4
VSEPRPLQERWVGLP

MMP28

356

Q9H239
SRPRSCTWPLQRPEL

FOXO3

26

O43524
DALWPPPDRVGRQEL

MAGOHB

76

Q96A72
QREARPTNRLPSDWL

RUSC2

1396

Q8N2Y8
PPEARPRNLTWIDSP

RTL1

371

A6NKG5
SRAERIRIPEPWITP

TRIM27

256

P14373
EPWLPLTDGRSPRRS

PLEKHN1

561

Q494U1
RQRWQRDLNPEPEPE

PPP1R12C

661

Q9BZL4
ARPQLQDAWRGPREP

EPPK1

3651

P58107
ARPQLQDAWRGPREP

EPPK1

4721

P58107
PRRESRTETRWGPRP

PRRC2A

916

P48634
RSWPSPKNRSRPPEE

PRRC2A

1431

P48634
QPRGDRRPELTDRPW

SHROOM2

356

Q13796
RRPELTDRPWRSAHP

SHROOM2

361

Q13796
SEPEREPEWRDRPGS

SHROOM3

896

Q8TF72
RDRDSSWAPPPREPV

SPATA31E1

1396

Q6ZUB1
VRRRPNLDPANPTTW

POM121L2

56

Q96KW2
RAPFTPTWPRSRERE

CTSO

26

P43234
RESDLDSWPVAPRPL

TBX10

251

O75333
ILPPRWDRDPDRRST

SHFL

186

Q9NUL5
WVNLRRGVPPPEDLR

PLEKHA6

321

Q9Y2H5
QTQDWVCEPPERRRP

TEX22

46

C9J3V5
DPVVRLWNPRPESED

WDTC1

601

Q8N5D0
WDRARPRDPSEDTPA

MINDY4

301

Q4G0A6
RLRRTPPAQRHPAWE

SPEG

2416

Q15772
LEDQWPSPPTRRAPV

SHC2

461

P98077
RDLNSFLWTIRRDPP

TRABD2B

36

A6NFA1
SQDRLEEVAAPRPWP

ARHGAP23

316

Q9P227
REESPEPQRPNWARS

STYXL2

1051

Q5VZP5
PDFRDLPEWEPRIRE

SOGA1

536

O94964
RRWEPSGKAEPRLPD

TBX6

156

O95947
WPRVPRPETAVARTL

F3

6

P13726
WRKDPPRADTPIREQ

ZC3H12D

136

A2A288
VENLLNPDSPRRPWL

XNDC1N

21

Q6ZNB5
PTPPLQLRWERDERP

nan

261

A8MUA0
QLRWERDERPPPAKL

nan

266

A8MUA0
LADRAIRWQRPSSPP

TPRN

406

Q4KMQ1
QDPLRPDTWLASRVP

TMEM129

331

A0AVI4
EGSRTWLEPREPRDP

ZNF831

511

Q5JPB2
QPLPPGWERRVDDRR

WWP1

381

Q9H0M0
DPTLRDPEAVARRWP

PRSS50

111

Q9UI38
EEWGRRHPEEPPSRR

ZNF335

706

Q9H4Z2
PDGNPRRESWTPRLS

ZFYVE26

136

Q68DK2
PPRHRLRNLRTESPW

ZNF669

26

Q96BR6
LEQELRALREPPTPW

N4BP3

521

O15049