Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainVWC

CHRD PXDNL FCGBP

1.53e-0538243SM00214
DomainVWF_dom

CHRD PXDNL FCGBP

2.07e-0542243IPR001007
DomainVWC

CHRD PXDNL

5.86e-0428242PF00093
DomainVWFC_1

CHRD PXDNL

9.71e-0436242PS01208
DomainVWFC_2

CHRD PXDNL

1.08e-0338242PS50184
DomainSushi

CSMD2 SVEP1

2.02e-0352242PF00084
DomainCCP

CSMD2 SVEP1

2.17e-0354242SM00032
DomainSUSHI

CSMD2 SVEP1

2.34e-0356242PS50923
DomainSushi_SCR_CCP_dom

CSMD2 SVEP1

2.42e-0357242IPR000436
DomainPH

DGKK GAB4 PSD4

3.04e-03229243PF00169
DomainPH

DGKK GAB4 PSD4

5.24e-03278243SM00233
DomainPH_DOMAIN

DGKK GAB4 PSD4

5.29e-03279243PS50003
DomainPH_domain

DGKK GAB4 PSD4

5.34e-03280243IPR001849
Pubmed

MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing.

AMHR2 KMT2D

2.74e-06424220808952
Pubmed

Extracellular HIV-1 viral protein R affects astrocytic glyceraldehyde 3-phosphate dehydrogenase activity and neuronal survival.

PXDNL DGKK

1.25e-042424223728617
Pubmed

Defects in GPI biosynthesis perturb Cripto signaling during forebrain development in two new mouse models of holoprosencephaly.

CHRD AMHR2

2.83e-043624223213481
Pubmed

Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).

CSMD2 FBXL17

3.16e-043824222952603
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

CHRD ALX4 PRKCSH

4.00e-0421024316537572
InteractionKRTAP12-3 interactions

KPRP CHRD LMNTD2 ZNF837

2.51e-05146244int:KRTAP12-3
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CSMD2 SVEP1

1.61e-03571921179
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

GAB4 PSD4

1.94e-02206192682
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PXDNL ALX4 SVEP1

4.06e-05125243b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCell343B-Epithelial_cells-Epithelial-E_(AT2)|343B / Donor, Lineage, Cell class and subclass (all cells)

CHRD MICAL2 ZNF837

6.31e-05145243cb534333fba44b241b14fb0d7b74e843f4e7f9f8
ToppCell343B-Epithelial_cells-Epithelial-E_(AT2)-|343B / Donor, Lineage, Cell class and subclass (all cells)

CHRD MICAL2 ZNF837

6.31e-0514524380684ec249fa445c1b35f94608a4a6824d53f2d9
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHRD ABCG4 DGKK

6.71e-05148243dfd3f2c4b884ea9e23831a242a89ac985b409640
ToppCell367C-Lymphocytic-NK_cells-NK_cell_C|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PXDNL GAB4 KIF18B

7.84e-05156243e6798d2b9c2c1fc6525c24f596f25aa85a375651
ToppCell367C-Lymphocytic-NK_cells-NK_cell_C|367C / Donor, Lineage, Cell class and subclass (all cells)

PXDNL GAB4 KIF18B

7.84e-05156243a1b9e7621b646d354c2ccd850ce6a4fa9ff8a026
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS10 ABCG4 SVEP1

8.30e-051592432607b562903228274fbd96168ba826782fab0b53
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS10 ABCG4 SVEP1

8.30e-05159243e812cbde59188924c6277c3feadf1a9592fa62a4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GAB4 WRAP53 KIF18B

1.07e-041732439f892d756d05e573af018db64edb130ff187ad47
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6|TCGA-Ovary / Sample_Type by Project: Shred V9

ADAMTS10 CHRD SVEP1

1.16e-04178243142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

CSMD2 CHRD SVEP1

1.18e-04179243cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCellnucseq-Epithelial-Epithelial_Glandular|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SPRR1B PLA2G2F FCGBP

1.18e-04179243859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SPRR1B PLA2G2F FCGBP

1.20e-041802433dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SPRR1B PLA2G2F FCGBP

1.20e-04180243668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMHR2 PLA2G2F FCGBP

1.22e-04181243dae0d106f0eee5dba538617f8ed724925ea35f17
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMHR2 PLA2G2F FCGBP

1.26e-04183243ee9c88be88221b7ad4ea9f890b17d6156fb3432e
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-Goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMHR2 PLA2G2F FCGBP

1.26e-04183243c52b84034503d931f7b87312d2ff86daff14152d
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PXDNL ALX4 SVEP1

1.54e-0419624357df2a57b35be9851ac0b1e5731baa53052511f0
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRD PXDNL SVEP1

1.56e-0419724371786e9432e2d649f5d86f639abb25e7102deb67
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS10 CHRD PXDNL

1.59e-041982437d2fe57e0f9311ac1e6854402ebc154306eb1ba5
ToppCellSkin-Fibroblasts|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

ADAMTS10 CHRD SVEP1

1.63e-04200243f777eadf571a1a6d246da87346a9cb9d511c2e81
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell|GW12 / Sample Type, Dataset, Time_group, and Cell type.

ADAMTS10 ZNF837 WRAP53

1.63e-042002436b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3-Excitatory_Neuron.Slc17a7.Pvrl3-Grm5_(CA3_Principal_cells)|Hippocampus / BrainAtlas - Mouse McCarroll V32

PLA2G2F FCGBP

1.89e-0438242b76689fb0e0845e0e42e332b3dca02bc0ad241b9
ComputationalNeighborhood of RFC1

KMT2D PRKCSH PSD4

2.09e-04109123MORF_RFC1
ComputationalNeighborhood of IKBKG

KMT2D PRKCSH PSD4

4.10e-04137123MORF_IKBKG
ComputationalNeighborhood of RPA2

KMT2D PRKCSH PSD4

1.11e-03193123MORF_RPA2
Diseaseesophagus squamous cell carcinoma (is_marker_for)

KMT2D WRAP53

1.39e-0374222DOID:3748 (is_marker_for)
Diseasecolorectal cancer (is_implicated_in)

ALX4 WRAP53

3.65e-03121222DOID:9256 (is_implicated_in)
Diseaselung non-small cell carcinoma (is_implicated_in)

KMT2D WRAP53

4.78e-03139222DOID:3908 (is_implicated_in)
Diseaseresting heart rate

FBXL17 MICAL2

5.48e-03149222EFO_0004351
Diseaseresponse to xenobiotic stimulus

CSMD2 FBXL17

8.06e-03182222GO_0009410
Diseasebreast cancer (is_marker_for)

KMT2D WRAP53

8.32e-03185222DOID:1612 (is_marker_for)
Diseasebody composition measurement

ADAMTS10 PXDNL

9.02e-03193222EFO_0005106
Diseasegout

PXDNL ALX4

9.29e-03196222EFO_0004274

Protein segments in the cluster

PeptideGeneStartEntry
SPVPACVVPCDPVPA

ALX4

316

Q9H161
CPPCPPEVDPIESHT

ABCG4

351

Q9H172
GPPPICEVHCPTNEL

CSMD2

2346

Q7Z408
PRPPVLEACHGPTCP

ADAMTS10

931

Q9H324
PPLCPEDCTSIPAPT

AMHR2

526

Q16671
PPETGVSHLCPEPPE

FAM47C

346

Q5HY64
PPETGVSHLCPEPPE

FAM47C

466

Q5HY64
PEPPETGVSHLCPEP

FAM47C

596

Q5HY64
EPCPELAPGPCPEAT

DGKK

56

Q5KSL6
ACPEPPPEAPTEDDH

PRKCSH

511

P14314
ETPTCLPDTTPHPAP

LMNTD2

31

Q8IXW0
PPEEVTCSHQSPAPP

PLA2G2F

151

Q9BZM2
CSESIPVPSPLCPEP

KIF18B

571

Q86Y91
CVVEICPPAPCPSPE

PXDNL

1426

A1KZ92
PTPCPPGSEDCIPSH

FCGBP

1431

Q9Y6R7
EEVVPDSPCLPPPTC

FCGBP

2621

Q9Y6R7
EPTSEPPVSHCVPPT

GAB4

191

Q2WGN9
NPCDCHREPPPETPD

FBXL17

306

Q9UF56
EIPEPRPCLQPCEHP

KPRP

456

Q5T749
PPVHSCCPKPEEATP

MICAL2

756

O94851
PDCCPSDQDPAPAHP

WRAP53

11

Q9BUR4
ECPRETCSHEDPPEP

PSD4

31

Q8NDX1
PLPHCERISCGVPPP

SVEP1

1681

Q4LDE5
PLPECVPVECPQPEE

SVEP1

2431

Q4LDE5
VICDPVVCPPPSCPH

CHRD

736

Q9H2X0
APAGETPPVCDPCPE

ZNF837

136

Q96EG3
VPEPCHPKVPEPCPS

SPRR1B

61

P22528
EEPHLSPQPEEPCLC

KMT2D

766

O14686
EPCLCAVPEEPHLSP

KMT2D

776

O14686