Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	GTPase activator activity	ARHGAP32 ARAP3 ARHGAP35 AGAP7P RAPGEF2 AGAP4 AGAP6 RASAL2	7.25e-06	279	72	8	GO:0005096
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	ARHGAP32 ARAP3 RIMS1 ARHGAP35 AGAP7P RAPGEF2 AGAP4 AGAP6 RASAL2	8.40e-05	507	72	9	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	ARHGAP32 ARAP3 RIMS1 ARHGAP35 AGAP7P RAPGEF2 AGAP4 AGAP6 RASAL2	8.40e-05	507	72	9	GO:0030695
GeneOntologyMolecularFunction	enzyme activator activity	ARHGAP32 NLRP12 ARAP3 DGKQ ARHGAP35 AGAP7P RAPGEF2 AGAP4 AGAP6 RASAL2	1.17e-04	656	72	10	GO:0008047
GeneOntologyMolecularFunction	phospholipid binding	SPTBN4 ARHGAP32 ARAP3 SPTBN2 ARHGAP35 AGAP7P RAPGEF2 AGAP4 AGAP6	1.51e-04	548	72	9	GO:0005543
GeneOntologyMolecularFunction	molecular function activator activity	ARHGAP32 NLRP12 ARAP3 METRNL DGKQ SEMA3G ARHGAP35 AGAP7P RAPGEF2 AGAP4 AGAP6 RASAL2 SEMA3E	4.16e-04	1233	72	13	GO:0140677
GeneOntologyMolecularFunction	structural constituent of synapse	SPTBN2 RIMS1 SHANK3	4.66e-04	42	72	3	GO:0098918
GeneOntologyMolecularFunction	lipid binding	SPTBN4 ARHGAP32 ARAP3 SPTBN2 HSD17B1 ARHGAP35 AGAP7P RAPGEF2 AGAP4 AGAP6 SULT1E1	7.80e-04	988	72	11	GO:0008289
GeneOntologyMolecularFunction	guanyl ribonucleotide binding	GTPBP6 ACSM5 ARHGAP35 AGAP7P RAPGEF2 AGAP4 AGAP6	1.02e-03	439	72	7	GO:0032561
GeneOntologyMolecularFunction	guanyl nucleotide binding	GTPBP6 ACSM5 ARHGAP35 AGAP7P RAPGEF2 AGAP4 AGAP6	1.02e-03	439	72	7	GO:0019001
GeneOntologyBiologicalProcess	neuron projection morphogenesis	SPTBN4 ARHGAP32 TET1 LAMA5 MACF1 EEF2K RIMS1 SEMA3G ARHGAP35 RAPGEF2 SHANK3 SEMA3E	1.98e-05	802	72	12	GO:0048812
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	SPTBN4 ARHGAP32 TET1 LAMA5 MACF1 EEF2K RIMS1 SEMA3G ARHGAP35 RAPGEF2 SHANK3 SEMA3E	2.43e-05	819	72	12	GO:0120039
GeneOntologyBiologicalProcess	cell projection morphogenesis	SPTBN4 ARHGAP32 TET1 LAMA5 MACF1 EEF2K RIMS1 SEMA3G ARHGAP35 RAPGEF2 SHANK3 SEMA3E	2.64e-05	826	72	12	GO:0048858
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	SPTBN4 ARHGAP32 TET1 LAMA5 MACF1 EEF2K SEMA3G ARHGAP35 RAPGEF2 SHANK3 SEMA3E	5.33e-05	748	72	11	GO:0048667
GeneOntologyBiologicalProcess	regulation of cellular component size	SPTBN4 ARHGAP32 ICAM1 SPTBN2 MACF1 SEMA3G ARHGAP35 SHANK3	1.17e-04	426	72	8	GO:0032535
MousePheno	abnormal sensory capabilities/reflexes/nociception	SPTBN4 NELL1 ARHGAP32 FOXRED2 ARAP3 MAP4K5 NT5DC2 RBM6 PEDS1 IREB2 INO80 HSD17B1 AGAP7P CMYA5 AGAP4 AGAP6 SHANK3 PCM1 RASAL2 SEMA3E	3.40e-06	1486	62	20	MP:0002067
MousePheno	abnormal reflex	SPTBN4 NELL1 ARHGAP32 FOXRED2 ARAP3 NT5DC2 RBM6 PEDS1 INO80 HSD17B1 AGAP7P CMYA5 AGAP4 AGAP6 SHANK3 PCM1 RASAL2 SEMA3E	7.85e-06	1294	62	18	MP:0001961
MousePheno	abnormal social recognition	CMYA5 SHANK3 PCM1	2.92e-05	14	62	3	MP:0020396
MousePheno	absent pinna reflex	PEDS1 AGAP7P AGAP4 AGAP6 RASAL2	4.54e-05	89	62	5	MP:0006358
MousePheno	abnormal habituation to a novel odor	ARHGAP32 SHANK3	5.79e-05	3	62	2	MP:0011622
MousePheno	abnormal pinna reflex	PEDS1 AGAP7P AGAP4 AGAP6 RASAL2	8.32e-05	101	62	5	MP:0001485
MousePheno	fused cornea and lens	AGAP7P AGAP4 AGAP6	1.57e-04	24	62	3	MP:0001307
Domain	ArfGap	ARAP3 AGAP7P AGAP4 AGAP6	4.48e-06	29	72	4	SM00105
Domain	ArfGap	ARAP3 AGAP7P AGAP4 AGAP6	4.48e-06	29	72	4	PF01412
Domain	ARFGAP	ARAP3 AGAP7P AGAP4 AGAP6	4.48e-06	29	72	4	PS50115
Domain	ArfGAP	ARAP3 AGAP7P AGAP4 AGAP6	4.48e-06	29	72	4	IPR001164
Domain	ANK	ANKRD65 AGAP7P BCOR ANKZF1 AGAP4 AGAP6 SHANK3	5.10e-05	251	72	7	SM00248
Domain	ANK_REPEAT	ANKRD65 AGAP7P BCOR ANKZF1 AGAP4 AGAP6 SHANK3	5.36e-05	253	72	7	PS50088
Domain	Ankyrin_rpt-contain_dom	ANKRD65 AGAP7P BCOR ANKZF1 AGAP4 AGAP6 SHANK3	5.50e-05	254	72	7	IPR020683
Domain	ANK_REP_REGION	ANKRD65 AGAP7P BCOR ANKZF1 AGAP4 AGAP6 SHANK3	5.50e-05	254	72	7	PS50297
Domain	Ankyrin_rpt	ANKRD65 AGAP7P BCOR ANKZF1 AGAP4 AGAP6 SHANK3	6.68e-05	262	72	7	IPR002110
Domain	NIPSNAP	NIPSNAP3B NIPSNAP3A	8.75e-05	4	72	2	IPR012577
Domain	Znf_B-box_chordata	TRIM27 TRIM7	8.75e-05	4	72	2	IPR020457
Domain	Spectrin_bsu	SPTBN4 SPTBN2	8.75e-05	4	72	2	IPR016343
Domain	NIPSNAP	NIPSNAP3B NIPSNAP3A	8.75e-05	4	72	2	PF07978
Domain	Actinin_actin-bd_CS	SPTBN4 SPTBN2 MACF1	9.20e-05	23	72	3	IPR001589
Domain	Spectrin	SPTBN4 SPTBN2 MACF1	9.20e-05	23	72	3	PF00435
Domain	ACTININ_2	SPTBN4 SPTBN2 MACF1	9.20e-05	23	72	3	PS00020
Domain	ACTININ_1	SPTBN4 SPTBN2 MACF1	9.20e-05	23	72	3	PS00019
Domain	PH	SPTBN4 ARAP3 SPTBN2 AGAP7P AGAP4 AGAP6 RASAL2	9.68e-05	278	72	7	SM00233
Domain	PH_DOMAIN	SPTBN4 ARAP3 SPTBN2 AGAP7P AGAP4 AGAP6 RASAL2	9.90e-05	279	72	7	PS50003
Domain	PH_domain	SPTBN4 ARAP3 SPTBN2 AGAP7P AGAP4 AGAP6 RASAL2	1.01e-04	280	72	7	IPR001849
Domain	Spectrin_repeat	SPTBN4 SPTBN2 MACF1	1.87e-04	29	72	3	IPR002017
Domain	PDZ	MAGIX RIMS1 RAPGEF2 SHANK3 PDZD2	2.13e-04	141	72	5	PF00595
Domain	PH_dom-like	SPTBN4 MTMR6 ARAP3 SPTBN2 AGAP7P AGAP4 AGAP6 RASAL2	2.29e-04	426	72	8	IPR011993
Domain	Spectrin/alpha-actinin	SPTBN4 SPTBN2 MACF1	2.51e-04	32	72	3	IPR018159
Domain	SPEC	SPTBN4 SPTBN2 MACF1	2.51e-04	32	72	3	SM00150
Domain	PDZ	MAGIX RIMS1 RAPGEF2 SHANK3 PDZD2	2.67e-04	148	72	5	SM00228
Domain	-	MAGIX RIMS1 RAPGEF2 SHANK3 PDZD2	2.84e-04	150	72	5	2.30.42.10
Domain	PDZ	MAGIX RIMS1 RAPGEF2 SHANK3 PDZD2	2.92e-04	151	72	5	PS50106
Domain	PDZ	MAGIX RIMS1 RAPGEF2 SHANK3 PDZD2	3.02e-04	152	72	5	IPR001478
Domain	Dimeric_a/b-barrel	NIPSNAP3B NIPSNAP3A	3.04e-04	7	72	2	IPR011008
Domain	RA	ARAP3 DGKQ RAPGEF2	3.58e-04	36	72	3	PF00788
Domain	Rho_GTPase_activation_prot	ARHGAP32 ARAP3 ARHGAP35 RASAL2	3.71e-04	88	72	4	IPR008936
Domain	-	ANKRD65 BCOR ANKZF1 AGAP4 AGAP6 SHANK3	3.88e-04	248	72	6	1.25.40.20
Domain	RA	ARAP3 DGKQ RAPGEF2	3.88e-04	37	72	3	PS50200
Domain	RA_dom	ARAP3 DGKQ RAPGEF2	4.90e-04	40	72	3	IPR000159
Domain	PH_dom-spectrin-type	SPTBN4 SPTBN2	5.18e-04	9	72	2	IPR001605
Domain	-	SPTBN4 MTMR6 ARAP3 SPTBN2 AGAP4 AGAP6 RASAL2	7.64e-04	391	72	7	2.30.29.30
Domain	Ank_2	ANKRD65 BCOR AGAP4 AGAP6 SHANK3	1.44e-03	215	72	5	PF12796
Domain	ConA-like_dom	NELL1 LAMA5 CMYA5 TRIM27 TRIM7	1.57e-03	219	72	5	IPR013320
Domain	RhoGAP	ARHGAP32 ARAP3 ARHGAP35	1.77e-03	62	72	3	SM00324
Domain	RhoGAP	ARHGAP32 ARAP3 ARHGAP35	1.85e-03	63	72	3	PF00620
Domain	PH	SPTBN4 ARAP3 SPTBN2 AGAP7P AGAP4	1.90e-03	229	72	5	PF00169
Domain	RHOGAP	ARHGAP32 ARAP3 ARHGAP35	1.93e-03	64	72	3	PS50238
Domain	RhoGAP_dom	ARHGAP32 ARAP3 ARHGAP35	1.93e-03	64	72	3	IPR000198
Domain	-	ARHGAP32 ARAP3 ARHGAP35	1.93e-03	64	72	3	1.10.555.10
Domain	CH	SPTBN4 SPTBN2 MACF1	2.02e-03	65	72	3	SM00033
Domain	CH	SPTBN4 SPTBN2 MACF1	2.50e-03	70	72	3	PF00307
Domain	HEAT_REPEAT	PDS5B SMG1 PDS5A	2.50e-03	70	72	3	PS50077
Domain	-	SPTBN4 SPTBN2 MACF1	2.60e-03	71	72	3	1.10.418.10
Domain	Semaphorin	SEMA3G SEMA3E	2.66e-03	20	72	2	IPR027231
Domain	CH	SPTBN4 SPTBN2 MACF1	2.82e-03	73	72	3	PS50021
Domain	CH-domain	SPTBN4 SPTBN2 MACF1	3.04e-03	75	72	3	IPR001715
Domain	SPRY	CMYA5 TRIM27 TRIM7	5.73e-03	94	72	3	PF00622
Domain	SPRY_dom	CMYA5 TRIM27 TRIM7	5.73e-03	94	72	3	IPR003877
Domain	B30.2/SPRY	CMYA5 TRIM27 TRIM7	5.90e-03	95	72	3	IPR001870
Domain	B302_SPRY	CMYA5 TRIM27 TRIM7	5.90e-03	95	72	3	PS50188
Domain	RA	DGKQ RAPGEF2	6.34e-03	31	72	2	SM00314
Domain	Sema	SEMA3G SEMA3E	6.34e-03	31	72	2	SM00630
Domain	Semap_dom	SEMA3G SEMA3E	6.34e-03	31	72	2	IPR001627
Domain	Sema	SEMA3G SEMA3E	6.34e-03	31	72	2	PF01403
Domain	SEMA	SEMA3G SEMA3E	6.34e-03	31	72	2	PS51004
Pathway	KEGG_MEDICUS_REFERENCE_ESTABLISHMENT_OF_COHESION	PDS5B PDS5A	2.77e-04	7	52	2	M47869
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	SPTBN4 SPTBN2 COL6A5	3.65e-04	38	52	3	MM14969
Pathway	REACTOME_NERVOUS_SYSTEM_DEVELOPMENT	SPTBN4 SPTBN2 COL6A5 ARHGAP35 SHANK3 SEMA3E	3.79e-04	261	52	6	MM15676
Pathway	REACTOME_COHESIN_LOADING_ONTO_CHROMATIN	PDS5B PDS5A	5.89e-04	10	52	2	M27178
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SPTBN4 SPTBN2	5.89e-04	10	52	2	MM15112
Pathway	REACTOME_COHESIN_LOADING_ONTO_CHROMATIN	PDS5B PDS5A	5.89e-04	10	52	2	MM14892
Pathway	REACTOME_ESTABLISHMENT_OF_SISTER_CHROMATID_COHESION	PDS5B PDS5A	7.19e-04	11	52	2	M27177
Pathway	REACTOME_ESTABLISHMENT_OF_SISTER_CHROMATID_COHESION	PDS5B PDS5A	7.19e-04	11	52	2	MM14891
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	ARHGAP32 SPTBN2 MACF1 RIMS1 AGAP7P RAPGEF2 AGAP4 AGAP6 SHANK3 RASAL2	4.60e-10	281	74	10	28706196
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SMG1 TET1 LAMA5 CACHD1 INO80 AGAP7P BCOR AGAP4 AGAP6 SEMA3E ZNF646	1.60e-08	529	74	11	14621295
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	SPTBN2 RIMS1 RAPGEF2 SEMA3E PDZD2 ZNF646	9.71e-08	104	74	6	9205841
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	SPTBN4 ARHGAP32 SPTBN2 MACF1 CACHD1 PDZD2	3.65e-07	130	74	6	12421765
Pubmed	GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.	AGAP7P AGAP4 AGAP6	7.70e-07	9	74	3	12640130
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SPTBN4 ARHGAP32 SENP1 SPTBN2 MACF1 RIMS1 JAKMIP3 RAPGEF2 BCOR SHANK3 PCM1 RASAL2	8.60e-07	963	74	12	28671696
Pubmed	AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.	AGAP7P AGAP4 AGAP6	1.10e-06	10	74	3	20664521
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	SPTBN4 ARHGAP32 SPTBN2 MACF1 RAPGEF2 SHANK3 RASAL2	1.12e-06	251	74	7	27507650
Pubmed	AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.	AGAP7P AGAP4 AGAP6	1.51e-06	11	74	3	15381706
Pubmed	The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin.	AGAP7P AGAP4 AGAP6	2.60e-06	13	74	3	27713690
Pubmed	GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.	AGAP7P AGAP4 AGAP6	3.31e-06	14	74	3	22453919
Pubmed	PDS5A and PDS5B differentially affect gene expression without altering cohesin localization across the genome.	PDS5B PDS5A	4.47e-06	2	74	2	35986423
Pubmed	PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection.	PDS5B PDS5A	4.47e-06	2	74	2	31757807
Pubmed	PDS5A and PDS5B in Cohesin Function and Human Disease.	PDS5B PDS5A	4.47e-06	2	74	2	34070827
Pubmed	Expression pattern and raft association of NIPSNAP3 and NIPSNAP4, highly homologous proteins encoded by genes in close proximity to the ATP-binding cassette transporter A1.	NIPSNAP3B NIPSNAP3A	4.47e-06	2	74	2	15177564
Pubmed	Pds5B is required for cohesion establishment and Aurora B accumulation at centromeres.	PDS5B PDS5A	1.34e-05	3	74	2	24141881
Pubmed	Pds5 Regulates Sister-Chromatid Cohesion and Chromosome Bi-orientation through a Conserved Protein Interaction Module.	PDS5B PDS5A	1.34e-05	3	74	2	28343969
Pubmed	Different attentional dysfunctions in eEF2K-/- , IL1RAPL1-/- and SHANK3Δ11-/- mice.	EEF2K SHANK3	1.34e-05	3	74	2	30838762
Pubmed	NT5DC2 promotes leiomyosarcoma tumour cell growth via stabilizing unpalmitoylated TEAD4 and generating a positive feedback loop.	NT5DC2 TRIM27	1.34e-05	3	74	2	33993634
Pubmed	In situ estrogen metabolism in proliferative endometria from untreated women with polycystic ovarian syndrome with and without endometrial hyperplasia.	HSD17B1 SULT1E1	2.67e-05	4	74	2	18467089
Pubmed	Structure and chromosomal localization of mouse G protein subunit gamma 4 gene.	LAMA5 TRIM27	2.67e-05	4	74	2	9570961
Pubmed	Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins.	PDS5B PDS5A	2.67e-05	4	74	2	29217591
Pubmed	Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay.	SMG1 UPF3A	2.67e-05	4	74	2	11544179
Pubmed	PDS5 proteins regulate the length of axial elements and telomere integrity during male mouse meiosis.	PDS5B PDS5A	2.67e-05	4	74	2	32285610
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	ARHGAP32 MACF1 AGAP7P RAPGEF2 AGAP4 AGAP6 SHANK3	3.71e-05	430	74	7	32581705
Pubmed	Successful inhibition of tumor development by specific class-3 semaphorins is associated with expression of appropriate semaphorin receptors by tumor cells.	SEMA3G SEMA3E	4.45e-05	5	74	2	18818766
Pubmed	Characterization of long cDNA clones from human adult spleen.	UNC13D SEMA3G ZNF160	4.82e-05	33	74	3	11214971
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SPTBN4 CACHD1 BCOR ZNF160	6.59e-05	101	74	4	10997877
Pubmed	Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates.	PDS5B PDS5A	6.66e-05	6	74	2	15837422
Pubmed	Characterization of human Smg5/7a: a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1.	SMG1 UPF3A	6.66e-05	6	74	2	12554878
Pubmed	In vivo assembly of the axon initial segment in motor neurons.	SPTBN4 SPTBN2	6.66e-05	6	74	2	23728480
Pubmed	Spectrins and ankyrinB constitute a specialized paranodal cytoskeleton.	SPTBN4 SPTBN2	6.66e-05	6	74	2	16687515
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SPTBN4 NELL1 GTPBP6 SPTBN2 MACF1 CACHD1 JAKMIP3 RAPGEF2 CMYA5 PCM1 RASAL2	8.30e-05	1285	74	11	35914814
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ARHGAP32 SPTBN2 MACF1 PDS5A ARHGAP35 ZNF160 SHANK3	8.74e-05	493	74	7	15368895
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	NELL1 ARHGAP32 MAGIX SPTBN2 RBM6 LAMA5 MACF1	9.08e-05	496	74	7	31343991
Pubmed	Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7.	SMG1 UPF3A	9.31e-05	7	74	2	14636577
Pubmed	Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts.	PDS5B PDS5A	9.31e-05	7	74	2	15855230
Pubmed	Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends.	SMG1 UPF3A	9.31e-05	7	74	2	17916692
Pubmed	Dosage effects of cohesin regulatory factor PDS5 on mammalian development: implications for cohesinopathies.	PDS5B PDS5A	9.31e-05	7	74	2	19412548
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	ARHGAP32 AGAP7P AGAP4 AGAP6 PCM1	1.05e-04	218	74	5	33378226
Pubmed	Distinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization.	PDS5B PDS5A	1.24e-04	8	74	2	29867216
Pubmed	Quantitative analysis of cohesin complex stoichiometry and SMC3 modification-dependent protein interactions.	PDS5B PDS5A	1.24e-04	8	74	2	21699228
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SENP1 NT5DC2 JAZF1 MACF1 INO80 RAPGEF2 BCOR TRIM27 PCM1 ZNF646	1.24e-04	1116	74	10	31753913
Pubmed	Expression of laminin alpha1, alpha2, alpha4, and alpha5 chains, fibronectin, and tenascin-C in skeletal muscle of dystrophic 129ReJ dy/dy mice.	ICAM1 LAMA5	1.59e-04	9	74	2	9882526
Pubmed	Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase.	PDS5B PDS5A	1.59e-04	9	74	2	17349791
Pubmed	Gene expression analysis of a panel of cell lines that differentially restrict HIV-1 CA mutants infection in a cyclophilin a-dependent manner.	TLL1 ICAM1	1.59e-04	9	74	2	24663101
Pubmed	Human Scc4 is required for cohesin binding to chromatin, sister-chromatid cohesion, and mitotic progression.	PDS5B PDS5A	1.59e-04	9	74	2	16682347
Pubmed	Human Wapl is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase.	PDS5B PDS5A	1.59e-04	9	74	2	17112726
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	SPTBN4 NELL1 MRPL21 LAMA5 AGAP7P TRIM27 SHANK3	1.92e-04	560	74	7	21653829
Pubmed	Scc1 sumoylation by Mms21 promotes sister chromatid recombination through counteracting Wapl.	PDS5B PDS5A	1.99e-04	10	74	2	22751501
Pubmed	Phosphorylation-enabled binding of SGO1-PP2A to cohesin protects sororin and centromeric cohesion during mitosis.	PDS5B PDS5A	1.99e-04	10	74	2	23242214
Pubmed	Sororin mediates sister chromatid cohesion by antagonizing Wapl.	PDS5B PDS5A	1.99e-04	10	74	2	21111234
Pubmed	Association of testicular germ cell tumor with polymorphisms in estrogen receptor and steroid metabolism genes.	HSD17B1 SULT1E1	2.43e-04	11	74	2	19776291
Pubmed	Brain proteins interacting with the tetramerization region of non-erythroid alpha spectrin.	SPTBN4 SPTBN2	2.43e-04	11	74	2	17607528
Pubmed	Wapl controls the dynamic association of cohesin with chromatin.	PDS5B PDS5A	2.43e-04	11	74	2	17113138
Pubmed	Variants in LRRC7 lead to intellectual disability, autism, aggression and abnormal eating behaviors.	MACF1 SHANK3	2.43e-04	11	74	2	39256359
Pubmed	APRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancer.	PDS5B PDS5A	2.43e-04	11	74	2	22293751
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ARHGAP32 CTPS2 MAP4K5 MACF1 CACHD1 RASAL2	2.81e-04	421	74	6	36976175
Pubmed	Semaphorin 3F is a bifunctional guidance cue for dopaminergic axons and controls their fasciculation, channeling, rostral growth, and intracortical targeting.	SEMA3G SEMA3E	2.91e-04	12	74	2	19812329
Pubmed	High-resolution mapping of mouse chromosome 8 identifies an evolutionary chromosomal breakpoint.	TLL1 PCM1	2.91e-04	12	74	2	9680377
Pubmed	Deletion of Sema3a or plexinA1/plexinA3 causes defects in sensory afferent projections of statoacoustic ganglion neurons.	SEMA3G SEMA3E	2.91e-04	12	74	2	23991118
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SPTBN4 SENP1 GTPBP6 TLL1 RBM6 MACF1 RIMS1 ARHGAP35 RAPGEF2 PCM1 PDZD2	2.99e-04	1489	74	11	28611215
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	USP30 GTPBP6 ZNF652 RBM6 LAMA5 MACF1 PDS5A INO80 BCOR ANKZF1 TRIM27	3.13e-04	1497	74	11	31527615
Pubmed	alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells.	SPTBN4 SPTBN2	3.43e-04	13	74	2	18796539
Pubmed	Semaphorin 3G Provides a Repulsive Guidance Cue to Lymphatic Endothelial Cells via Neuropilin-2/PlexinD1.	SEMA3G SEMA3E	3.43e-04	13	74	2	27880905
Pubmed	Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2.	DGKQ ZNF646	4.00e-04	14	74	2	22451204
Pubmed	Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay.	SMG1 UPF3A	4.00e-04	14	74	2	16452507
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	MTMR6 MRPL21 FOXRED2 GTPBP6 LAMA5 MACF1 PDS5A NIPSNAP3A ANKZF1 PCM1	4.13e-04	1297	74	10	33545068
Pubmed	Aurora B and Cdk1 mediate Wapl activation and release of acetylated cohesin from chromosomes by phosphorylating Sororin.	PDS5B PDS5A	4.61e-04	15	74	2	23901111
Pubmed	Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.	THSD4 NELL1 JAZF1	4.76e-04	71	74	3	23400010
Pubmed	Ontogeny of stromal organizer cells during lymph node development.	ICAM1 LAMA5	5.26e-04	16	74	2	20237296
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	CTPS2 NT5DC2 MACF1	5.81e-04	76	74	3	27542412
Pubmed	Polymorphisms in genes of the steroid hormone biosynthesis and metabolism pathways and endometrial cancer risk.	HSD17B1 SULT1E1	5.95e-04	17	74	2	20381444
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	ARHGAP32 SENP1 RBM6 BCOR	6.02e-04	180	74	4	35198878
Pubmed	Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.	SPTBN4 SPTBN2	6.68e-04	18	74	2	12119179
Pubmed	The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex.	SMG1 UPF3A	6.68e-04	18	74	2	25220460
Pubmed	Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity.	RASAL2 CHST8	8.28e-04	20	74	2	19079260
Pubmed	A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects.	METRNL NT5DC2	8.28e-04	20	74	2	34127677
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SPTBN4 ARHGAP32 SPTBN2 MACF1 RIMS1 ARHGAP35 RAPGEF2 SHANK3 PCM1 RASAL2	8.82e-04	1431	74	10	37142655
Pubmed	Motor neurons use push-pull signals to direct vascular remodeling critical for their connectivity.	SEMA3G SEMA3E	9.14e-04	21	74	2	36240771
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	MACF1 ARHGAP35 PCM1 RASAL2	1.05e-03	209	74	4	36779422
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	ARHGAP32 LAMA5 IREB2 ZNF112 ANKZF1	1.08e-03	363	74	5	14691545
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	MTMR6 SPTBN2 TET1 ARHGAP35 BCOR PCM1	1.13e-03	549	74	6	38280479
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	SENP1 MRPL21 MAP4K5 NT5DC2 SPTBN2 MACF1 EEF2K TRIM27 PCM1 RASAL2	1.18e-03	1487	74	10	33957083
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	PDS5B USP30 METRNL TET1 PEDS1 AGAP7P AGAP4 AGAP6 RASAL2	1.26e-03	1242	74	9	30973865
Pubmed	Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.	NT5DC2 SPTBN2 SEMA3G	1.36e-03	102	74	3	21926972
Pubmed	Functional interactions between ubiquitin E2 enzymes and TRIM proteins.	TRIM27 TRIM7	1.51e-03	27	74	2	21143188
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	EEF2K CACHD1 RAPGEF2 BCOR	1.54e-03	232	74	4	25515538
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	SENP1 MACF1 BCOR TRIM27	1.59e-03	234	74	4	36243803
Pubmed	Alternatively spliced isoforms of WT1 control podocyte-specific gene expression.	SEMA3G SEMA3E	1.63e-03	28	74	2	25993318
Pubmed	PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.	PDS5B RBM6 TRIM27 PCM1	1.94e-03	247	74	4	32989298
Pubmed	Integration of repulsive guidance cues generates avascular zones that shape mammalian blood vessels.	SEMA3G SEMA3E	2.00e-03	31	74	2	22076636
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	PDS5B SPTBN2 RBM6 MACF1 PDS5A UPF3A INO80 ARHGAP35	2.10e-03	1082	74	8	38697112
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	MTMR6 ZNF652 TET1 MACF1 UNC13D INO80 BCOR CHST8	2.12e-03	1084	74	8	11544199
Interaction	CPS1 interactions	MRPL21 NIPSNAP3B LDHAL6B ACSM5 NIPSNAP3A KIRREL2	1.17e-05	138	74	6	int:CPS1
Cytoband	10q11.23	AGAP7P AGAP6	1.35e-03	33	75	2	10q11.23
Cytoband	16p12.3	SMG1 ACSM5	1.43e-03	34	75	2	16p12.3
Cytoband	9q31.1	NIPSNAP3B NIPSNAP3A	2.07e-03	41	75	2	9q31.1
Cytoband	3p21.1	NT5DC2 SEMA3G	2.17e-03	42	75	2	3p21.1
Cytoband	Ensembl 112 genes in cytogenetic band chr16p12	SMG1 ACSM5 EEF2K	2.86e-03	172	75	3	chr16p12
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	SPTBN4 NLRP12 ZNF112 ARHGAP35 KIRREL2 ZNF160 CHST8	3.35e-03	1192	75	7	chr19q13
Cytoband	Ensembl 112 genes in cytogenetic band chr10q11	AGAP7P AGAP4 AGAP6	3.68e-03	188	75	3	chr10q11
GeneFamily	Ankyrin repeat domain containing	ANKRD65 ARAP3 AGAP7P BCOR ANKZF1 AGAP4 AGAP6 SHANK3	6.50e-07	242	55	8	403
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	SPTBN4 ARAP3 SPTBN2 AGAP7P AGAP4 AGAP6 RASAL2	2.87e-06	206	55	7	682
GeneFamily	ArfGAPs	ARAP3 AGAP7P AGAP4 AGAP6	2.94e-06	33	55	4	395
GeneFamily	PDZ domain containing	MAGIX RIMS1 RAPGEF2 SHANK3 PDZD2	9.75e-05	152	55	5	1220
GeneFamily	EF-hand domain containing\|Spectrins	SPTBN4 SPTBN2	1.89e-04	7	55	2	1113
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	AGAP4 AGAP6	1.20e-03	17	55	2	1291
GeneFamily	Immunoglobulin like domain containing\|Semaphorins	SEMA3G SEMA3E	1.67e-03	20	55	2	736
GeneFamily	Immunoglobulin like domain containing	ICAM1 SEMA3G KIRREL2 SEMA3E	2.81e-03	193	55	4	594
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	CMYA5 TRIM27 TRIM7	3.03e-03	95	55	3	59
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP32 ARHGAP35	1.01e-02	50	55	2	721
ToppCell	AT1-AT2_cells-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	THSD4 NT5DC2 ICAM1 KIRREL2 SEMA3E PDZD2	5.12e-07	175	75	6	bdd85ba280648a0283c1984662a34c7b840f64dd
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	METRNL TLL1 MACF1 KCNMB4 ZNF160 SHANK3	6.04e-07	180	75	6	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D231\|Adult / Lineage, Cell type, age group and donor	THSD4 ICAM1 LAMA5 UNC13D SEMA3E PDZD2	8.03e-07	189	75	6	5a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCell	COVID-19-Endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	ARAP3 TLL1 KCNMB4 SEMA3G SHANK3 SULT1E1	8.28e-07	190	75	6	9fbd92cd6d4683b2490504d29c43cf42020433d4
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ARAP3 LAMA5 KCNMB4 RIMS1 SEMA3G SHANK3	9.35e-07	194	75	6	68004855b23fe1e31e8452d70effabc78a4a0bd3
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARAP3 TLL1 CACHD1 SEMA3G SHANK3 RASAL2	9.35e-07	194	75	6	74a9fdb73f279bebb6337510deab9aaaf9f7e957
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ARAP3 TLL1 ICAM1 SHANK3 RASAL2	9.93e-07	196	75	6	48b4a9cea97a55190217deaf51bf867608c5a9a7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ARAP3 TLL1 ICAM1 SHANK3 RASAL2	9.93e-07	196	75	6	473980c827443464d08a0be28c53e3536369b12a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARAP3 TLL1 CACHD1 SEMA3G SHANK3 RASAL2	9.93e-07	196	75	6	adee900dcd16dbaba15c58bdcace09ba20214950
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARAP3 TLL1 CACHD1 SEMA3G SHANK3 RASAL2	9.93e-07	196	75	6	22767bcf0095d9eb0cbed7cdc74e4d32d9357e1b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ARAP3 TLL1 ICAM1 SHANK3 RASAL2	9.93e-07	196	75	6	8f2031b1a9232c389517fbf3c29f47f9468b0077
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARAP3 TLL1 KCNMB4 SEMA3G SHANK3 SULT1E1	1.05e-06	198	75	6	002424b24dacac553e02d0f764a6e8a1e567b9df
ToppCell	droplet-Fat-Scat-21m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN4 MAGIX RAPGEF2 SHANK3 PDZD2	1.10e-05	173	75	5	f13124b4cf2ac1dc2895f90f5487d6ac681b0ba4
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARAP3 METRNL JAZF1 RAPGEF2 ANKZF1	1.16e-05	175	75	5	c1c722db42da9b8a2a46e516ddb83d9be5e2e504
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D175\|Adult / Lineage, Cell type, age group and donor	ARAP3 TLL1 KCNMB4 SEMA3G SHANK3	1.16e-05	175	75	5	0a65ddfa8c2e8efb5b5338cf07661cb78157a23c
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SMG1 ARHGAP32 MACF1 RIMS1 CMYA5	1.30e-05	179	75	5	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARAP3 TLL1 CACHD1 SHANK3 RASAL2	1.30e-05	179	75	5	8f9e538c822940785130297712b75131812a4603
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ARAP3 TLL1 SHANK3 RASAL2	1.44e-05	183	75	5	dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ARAP3 TLL1 SHANK3 RASAL2	1.44e-05	183	75	5	4759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCell	COVID-19-Endothelial_cells-Arterial_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	TLL1 KCNMB4 SEMA3G SHANK3 PDZD2	1.48e-05	184	75	5	0f19494789f38ab1a420545e15e748ca7eb345c3
ToppCell	Endothelial-A-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	TLL1 KCNMB4 SEMA3G SHANK3 SULT1E1	1.52e-05	185	75	5	dee0b7ba2f338f0979d2306aedf52ac35a36b60c
ToppCell	Adult-Endothelial-endothelial_cell_of_artery\|Adult / Lineage, Cell type, age group and donor	ARAP3 TLL1 KCNMB4 SEMA3G SHANK3	1.56e-05	186	75	5	2d1c4ea2e401db89971582ee54618a8b0c81b8ac
ToppCell	Control-Endothelial_cells-Endothelial_cells_(general)\|Control / group, cell type (main and fine annotations)	ARAP3 KCNMB4 RIMS1 SEMA3G SHANK3	1.60e-05	187	75	5	fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1\|Adult / Lineage, Cell type, age group and donor	THSD4 LAMA5 UNC13D SEMA3E PDZD2	1.60e-05	187	75	5	77f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell	Control-Endothelial_cells-Arterial_endothelial_cells\|Control / group, cell type (main and fine annotations)	ARAP3 TLL1 KCNMB4 SEMA3G SHANK3	1.60e-05	187	75	5	81affaab3fe3e1daea45ada6445e906ddd33950e
ToppCell	Endothelial-endothelial_cell_of_artery\|World / Lineage, Cell type, age group and donor	ARAP3 TLL1 KCNMB4 SEMA3G SHANK3	1.69e-05	189	75	5	fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARAP3 KCNMB4 SEMA3G SHANK3 SULT1E1	1.73e-05	190	75	5	bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCell	COVID-19-Heart-EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	LAMA5 RIMS1 RAPGEF2 SHANK3 PDZD2	1.73e-05	190	75	5	a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell	COVID-19-lung-Artery_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARAP3 TLL1 KCNMB4 SEMA3G SHANK3	1.73e-05	190	75	5	07b675befcd1d0a9c90cb17b5d22323468325d51
ToppCell	COVID-19-kidney-VWF+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARAP3 TLL1 KCNMB4 SHANK3 RASAL2	1.77e-05	191	75	5	2f00d0b7b2ffce8eb3eb5bbae49a0d425b23c982
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ARAP3 TLL1 KCNMB4 SEMA3G SHANK3	1.77e-05	191	75	5	50601ef0a5a8f2c2120922989e08e85bf2d9b4ab
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ARAP3 SEMA3G SHANK3 SULT1E1	1.77e-05	191	75	5	b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ARAP3 TLL1 SHANK3 RASAL2	1.91e-05	194	75	5	ad6c04ad0621689e3bf4c94ccd6e60653bbd02c7
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ARAP3 KCNMB4 RIMS1 SEMA3G SHANK3	1.91e-05	194	75	5	71ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCell	Adult-Endothelial\|Adult / Lineage, Cell type, age group and donor	ARAP3 TLL1 KCNMB4 SEMA3G SHANK3	1.91e-05	194	75	5	963b3fbee0575af8379baa397ace65949eaf34f7
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ARAP3 KCNMB4 RIMS1 SEMA3G SHANK3	1.91e-05	194	75	5	40842a7160f337bfc191ee15fbda3e3d38a04c57
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARAP3 TLL1 KCNMB4 SEMA3G SHANK3	2.01e-05	196	75	5	915e4a7422058be246b54760df31e8a607310625
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ARAP3 TLL1 CACHD1 SHANK3	2.01e-05	196	75	5	e224338490691d92c1f70b57112fabdcc92b06a9
ToppCell	COVID-19-lung-Capillary_Aerocytes\|lung / Disease (COVID-19 only), tissue and cell type	THSD4 ARAP3 LAMA5 SHANK3 RASAL2	2.01e-05	196	75	5	4ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ARAP3 TLL1 CACHD1 SHANK3	2.06e-05	197	75	5	c10dd1aaec01fb662eac83dfde90e3e426665d65
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ARAP3 TLL1 CACHD1 SHANK3	2.06e-05	197	75	5	2844dbcd0a673ed81c99920aa45858651a00736d
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_capillary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARAP3 KCNMB4 RIMS1 SEMA3G SHANK3	2.06e-05	197	75	5	81718164c9802ee20c860ffbda7e62d5e9a76f16
ToppCell	COVID-19-lung-Capillary_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARAP3 TLL1 LAMA5 KCNMB4 SHANK3	2.11e-05	198	75	5	45419f2804b4be79bae6632e71c54e1af482d115
ToppCell	Endothelial-A\|World / lung cells shred on cell class, cell subclass, sample id	TLL1 KCNMB4 SEMA3G SHANK3 SULT1E1	2.11e-05	198	75	5	dd096d4b9f428615f927f7df7cbf5cede0e0e605
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	NELL1 DGKQ MACF1 COL6A5 JAKMIP3	2.11e-05	198	75	5	0c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Capillary\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ARAP3 LAMA5 KCNMB4 SEMA3G SHANK3	2.16e-05	199	75	5	3fea92affacd4c1f588fa81807df35d6c69b7241
ToppCell	COVID-19-lung-Capillary_2\|lung / Disease (COVID-19 only), tissue and cell type	ARAP3 TLL1 LAMA5 KCNMB4 SHANK3	2.16e-05	199	75	5	793ce71b78a68033ef4419ed571e1dd86b40124f
ToppCell	Lung_Parenchyma-Control-Endothelial-Endothelial-Capillary-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ARAP3 LAMA5 KCNMB4 SEMA3G SHANK3	2.16e-05	199	75	5	993999adf346b4fd557989bc53c17eb0ccb996c9
ToppCell	Parenchyma_Control_(B.)-Endothelial-TX-Capillary\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	ARAP3 LAMA5 KCNMB4 SEMA3G SHANK3	2.16e-05	199	75	5	89f4db619fbed90f7fdf6ece7a671e514b5c6d76
ToppCell	5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARAP3 TLL1 LAMA5 SEMA3G SHANK3	2.21e-05	200	75	5	cd3c638961144a2fc91c437a173cc37c7452fa74
ToppCell	Control-NK\|World / Disease group and Cell class	SPTBN4 KCNMB4 CACHD1 RASAL2	9.98e-05	143	75	4	fe08adc9472dfd4242497d6c614d0490713261da
ToppCell	Control-Plasmablast\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	NELL1 NT5DC2 LAMA5 SEMA3G	1.05e-04	145	75	4	fe68582f5a15b9714cb84fa32ac880e13cb69895
ToppCell	LPS-IL1RA-Endothelial-Mes-Like-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KCNMB4 RIMS1 HSD17B1 PPWD1	1.05e-04	145	75	4	90ca38c02325c5c637c32efdef634b54cc3cd105
ToppCell	Control-B_intermediate-10\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SPTBN4 METRNL JAZF1 ACSM5	1.61e-04	162	75	4	aa80452b972bb8ad3670ffaba4ce26fadb33b185
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TLL1 CACHD1 SHANK3 RASAL2	1.61e-04	162	75	4	c399b9e4854916a59f5cae2d8dbf19660f8759be
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar-Club_cell\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	STX19 MAGIX ZNF112 CMYA5	1.61e-04	162	75	4	aed15eef32419b8a4e2afdb9776c2bf2802e96f1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TLL1 CACHD1 SHANK3 RASAL2	1.61e-04	162	75	4	a291248b693c771845174393934a782f1d8bd7ce
ToppCell	facs-Marrow-Granulocytes-18m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NLRP12 SPTBN2 JAZF1 SEMA3G	1.65e-04	163	75	4	7a04192710f55acf5a4681d5f09942358fdb02ff
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD4 USP30 KIRREL2 ANKZF1	1.69e-04	164	75	4	b895674ed2df87db8fbfb30b7e31620945588491
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TLL1 JAKMIP3 SHANK3 SULT1E1	1.81e-04	167	75	4	d7fe24cdc4b55a9555ce9e20699f5036b88148e9
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D122\|Adult / Lineage, Cell type, age group and donor	ARAP3 KCNMB4 SEMA3G SHANK3	1.85e-04	168	75	4	8c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARAP3 KCNMB4 SEMA3G SHANK3	1.90e-04	169	75	4	987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	RBM6 LAMA5 UNC13D RASAL2	1.90e-04	169	75	4	6614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	RBM6 LAMA5 UNC13D RASAL2	1.90e-04	169	75	4	665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	ICAM1 LAMA5 RASAL2 PDZD2	1.94e-04	170	75	4	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ARAP3 TLL1 KCNMB4 SHANK3	1.98e-04	171	75	4	1597459c971d6befa991d59dc66b41b6a522f797
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARAP3 KCNMB4 SHANK3 RASAL2	2.07e-04	173	75	4	f193c63cc536d891c9d23043765e320252bb6e65
ToppCell	droplet-Lung-30m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	JAZF1 UNC13D EEF2K HSD17B1	2.12e-04	174	75	4	009e88a6c79689a5d88b0af50aa89aa03b33f800
ToppCell	droplet-Lung-30m-Hematologic-myeloid-Basophil/Mast_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	JAZF1 EEF2K HSD17B1 BCOR	2.12e-04	174	75	4	e9e4532a474b4b0938a50ff85c9508aca53cd3ae
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NLRP12 ICAM1 SHANK3 RASAL2	2.12e-04	174	75	4	42735f6a8e5ec36dd3d35aceea6d37cf3eaa1871
ToppCell	P03-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ICAM1 MACF1 CHST8 SEMA3E	2.21e-04	176	75	4	f3a54038cde58326f1caed96ecca33c141bcc8b3
ToppCell	Adult-Endothelial-endothelial_cell_of_vein\|Adult / Lineage, Cell type, age group and donor	ARAP3 TLL1 SHANK3 SULT1E1	2.21e-04	176	75	4	043683c61c5d1a7f8a4666a612310246bd3d83a2
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARAP3 SEMA3G SHANK3 SULT1E1	2.26e-04	177	75	4	5ff8dcfb030312126695d53a026d2e104a401b83
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA5 CACHD1 SEMA3G TRIM7	2.36e-04	179	75	4	a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 NELL1 RIMS1 HSD17B1	2.36e-04	179	75	4	02c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_Erythro-Mega\|lymph-node_spleen / Manually curated celltypes from each tissue	NT5DC2 SPTBN2 PEDS1 SHANK3	2.36e-04	179	75	4	957c08ad4b46eb4cc1717c45056fc3db50015fdc
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SEMA3G RAPGEF2 SHANK3 PDZD2	2.36e-04	179	75	4	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TLL1 KCNMB4 SHANK3 SULT1E1	2.41e-04	180	75	4	27e8bbee388e64dd79d70b160b76d45b1f398006
ToppCell	COVID-19-Endothelial_cells-Capillary_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	THSD4 ARAP3 LAMA5 SHANK3	2.46e-04	181	75	4	c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(other)\|COVID-19 / group, cell type (main and fine annotations)	LAMA5 KCNMB4 SEMA3G SHANK3	2.46e-04	181	75	4	26eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCell	COVID-19-Heart-EC_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARAP3 TLL1 SHANK3 RASAL2	2.57e-04	183	75	4	ff95382cfed592190d0636d2b750328471f82e0d
ToppCell	Control-Endothelial_cells-Pulmonary_venous_endothelial_cells\|Control / group, cell type (main and fine annotations)	TLL1 KCNMB4 SHANK3 SULT1E1	2.57e-04	183	75	4	46be9f96755c7b65aeac061d95d15abeb6466034
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D122\|Adult / Lineage, Cell type, age group and donor	LAMA5 UNC13D SEMA3E PDZD2	2.62e-04	184	75	4	561592edc3083fad41b91811151b442207c65dd9
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 MACF1 PDS5A PCM1	2.62e-04	184	75	4	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	COVID-19-Endothelial_cells-Systemic_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	TLL1 KCNMB4 CACHD1 SHANK3	2.68e-04	185	75	4	f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D231\|Adult / Lineage, Cell type, age group and donor	ARAP3 RIMS1 SEMA3G SHANK3	2.68e-04	185	75	4	07f9f38f0739d7c830641723a38385550ac1ac92
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	THSD4 ICAM1 RASAL2 SEMA3E	2.68e-04	185	75	4	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TLL1 KCNMB4 SEMA3G SHANK3	2.68e-04	185	75	4	a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	METRNL TLL1 KCNMB4 SHANK3	2.68e-04	185	75	4	673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCell	Control-Endothelial_cells-Endothelial_cells_(other)\|Control / group, cell type (main and fine annotations)	ARAP3 TLL1 KCNMB4 SHANK3	2.73e-04	186	75	4	c6075fe84226b370c5139066793844ad33ae2db1
ToppCell	Control-Myeloid-MoAM3,_VCAN\|Myeloid / Condition, Lineage and Cell class	NLRP12 NT5DC2 CACHD1 TRIM7	2.73e-04	186	75	4	0bf16ac48931b62bb3c33d63ff4279654148e293
ToppCell	Epithelial-alveolar_epithelial_cell_type_1\|World / Lineage, Cell type, age group and donor	ICAM1 LAMA5 UNC13D SEMA3E	2.73e-04	186	75	4	09d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	METRNL ICAM1 NIPSNAP3A PDZD2	2.73e-04	186	75	4	b9e0a819cd0b250f077b26eba99e6986d68d647b
ToppCell	Adult-Epithelial-club_cell-D231\|Adult / Lineage, Cell type, age group and donor	NELL1 TLL1 RIMS1 SEMA3E	2.79e-04	187	75	4	ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCell	COPD-Endothelial-VE_Arterial\|World / Disease state, Lineage and Cell class	TLL1 KCNMB4 SEMA3G SHANK3	2.79e-04	187	75	4	be42ee71d3412bb1f52593d8814de85c354a0efa
ToppCell	Endothelial-A-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	KCNMB4 SEMA3G SHANK3 SULT1E1	2.79e-04	187	75	4	fd93f3f4b82dae3bf4eef245bfedc2a9e3251b61
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ICAM1 LAMA5 UNC13D SEMA3E	2.79e-04	187	75	4	4ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARAP3 TLL1 SHANK3 RASAL2	2.79e-04	187	75	4	35c382c0aabd46906113e5db30ea24bb8e658899
ToppCell	COVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	TLL1 KCNMB4 SHANK3 SULT1E1	2.79e-04	187	75	4	2d20193a6cacdfa4877457c97b0077408942186c
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ICAM1 LAMA5 UNC13D SEMA3E	2.85e-04	188	75	4	eea652bab161f19148a883e7e3fe2523b36b3cea
Computational	Genes in the cancer module 67.	SPTBN4 SMG1 GTPBP6 ZNF652 NIPSNAP3A ZNF112 PDZD2	3.36e-05	227	44	7	MODULE_67
Disease	cerebral palsy (implicated_via_orthology)	AGAP7P AGAP4 AGAP6	1.58e-06	10	71	3	DOID:1969 (implicated_via_orthology)
Disease	RNA polymerase II subunit A C-terminal domain phosphatase SSU72 measurement	NLRP12 DGKQ	5.71e-06	2	71	2	EFO_0802029
Disease	spinocerebellar ataxia type 5 (implicated_via_orthology)	SPTBN4 SPTBN2	3.41e-05	4	71	2	DOID:0050882 (implicated_via_orthology)
Disease	spine bone mineral density change measurement, response to combination chemotherapy	NELL1 TLL1	5.68e-05	5	71	2	EFO_0007965, EFO_0008474
Disease	neural cell adhesion molecule 1, 120 kda isoform measurement	MAP4K5 NT5DC2	8.51e-05	6	71	2	EFO_0020593
Disease	neuropilin-1 measurement	NELL1 MAP4K5	1.19e-04	7	71	2	EFO_0020603
Disease	sialic acid-binding Ig-like lectin 12 measurement	NLRP12 MAP4K5	1.58e-04	8	71	2	EFO_0802066
Disease	response to hydrochlorothiazide, triglyceride measurement	THSD4 NELL1 JAZF1	2.01e-04	47	71	3	EFO_0004530, EFO_0005202
Disease	Prostatic Neoplasms	ICAM1 JAZF1 PDS5A UNC13D HSD17B1 ZNF160 SULT1E1	6.99e-04	616	71	7	C0033578
Disease	Malignant neoplasm of prostate	ICAM1 JAZF1 PDS5A UNC13D HSD17B1 ZNF160 SULT1E1	6.99e-04	616	71	7	C0376358
Disease	urate measurement, bone density	THSD4 NELL1 MAP4K5 RBM6 LAMA5 COL6A5 PDZD2	7.20e-04	619	71	7	EFO_0003923, EFO_0004531
Disease	lung carcinoma	PDS5B SENP1 ARAP3 COL6A5 RIMS1 TRIM27	1.08e-03	482	71	6	EFO_0001071
Disease	serum alanine aminotransferase measurement	PDS5B MAP4K5 TET1 RBM6 JAZF1 LAMA5 CMYA5 SEMA3E	1.13e-03	869	71	8	EFO_0004735
Disease	HbA1c measurement	HAUS8 SENP1 METRNL MAP4K5 TET1 JAZF1 MACF1	1.19e-03	675	71	7	EFO_0004541
Disease	inflammatory bowel disease (implicated_via_orthology)	ANKZF1 PDZD2	1.65e-03	25	71	2	DOID:0050589 (implicated_via_orthology)
Disease	pulse pressure measurement	THSD4 SPTBN4 SENP1 TET1 LAMA5 UNC13D UPF3A INO80 HSD17B1 PCM1	1.77e-03	1392	71	10	EFO_0005763
Disease	alpha fetoprotein measurement	MAP4K5 TET1 JAZF1	1.83e-03	100	71	3	EFO_0010583
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	PDS5B TET1 MACF1 JAKMIP3 HSD17B1	1.86e-03	364	71	5	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946

Protein segments in the cluster

Peptide	Gene	Start	Entry
RHVETTVDELVRHFF	nan	146	A8MT66
LEIPHHITQRDADRS	AGAP4	146	Q96P64
TFEIREHGELERPLH	ARAP3	1166	Q8WWN8
RFIAAVIERHAHSPE	CACHD1	1166	Q5VU97
EEVLEAALRAHHIPE	DGKQ	326	P52824
SHDPEALTRELQEHV	ACSM5	526	Q6NUN0
TRPLHDAVENDHLEI	BCOR	1531	Q6W2J9
LEIPHHITQRDADRT	AGAP6	146	Q5VW22
KVRSHDPEEAIRHDV	PDS5B	356	Q9NTI5
HKSHEDPRVVAAVRE	NIPSNAP3A	211	Q9UFN0
KVRSHDPEEAIRHDV	PDS5A	366	Q29RF7
PSREEVHRVEEEHVI	IREB2	666	P48200
RDEELSSEESPRRHH	INO80	231	Q9ULG1
EVTDSRLPHATIVDH	MAGIX	76	Q9H6Y5
DLILHVRDVSHPEAE	GTPBP6	376	O43824
RTVHFIVPRERDCHD	MTMR6	76	Q9Y217
EHIEDNHIDTDPRVL	JAZF1	31	Q86VZ6
HRSSLVDEHPEDAEF	PCM1	641	Q15154
ELIERFTSEKPVHHS	LDHAL6B	56	Q9BYZ2
VSQRLHVADHEDPDR	PDZD2	1931	O15018
HKSHEDPRVVAAVRE	NIPSNAP3B	211	Q9BS92
HIDPTAITRHDFIET	PEDS1	121	A5PLL7
SEDFSRRHTVPDRHI	RASAL2	841	Q9UJF2
HLDHREPQSESVTLE	MACF1	181	O94854
EERERKSPAISFHHT	JAKMIP3	616	Q5VZ66
HEPERQDSAIHLRVS	METRNL	216	Q641Q3
SVEERDHAGRTPLHL	ANKRD65	66	E5RJM6
LHHLRLELEEAATPE	LAMA5	871	O15230
RPTAIHHIVEDFLTD	FOXRED2	556	Q8IWF2
HSEEDDFVPELHRNV	ARHGAP32	46	A7KAX9
QRLRHEFDSEHVPDL	ARHGAP32	416	A7KAX9
DTTRHELPVRSIHLE	HAUS8	241	Q9BT25
HRSLSHELEDLEIRP	OOSP4A	141	A0A2R8YFL7
QDIEREIHAAPHVSE	NELL1	61	Q92832
HERRHSDVALPRTEA	RIMS1	386	Q86UR5
LHVYEEDPREAVRLH	ANKZF1	346	Q9H8Y5
PEEVLDRTDIHTFHR	HSD17B1	201	P14061
IAVLVTHRPSDDEVH	COL6A5	341	A8TX70
PFEDTHHVLERADEA	CMYA5	3341	Q8N3K9
LEIPHHITQRDADRS	AGAP7P	146	Q5VUJ5
PDDVLLHRTHDEIVL	KCNMB4	156	Q86W47
HDLHIRPVELEDEAS	KIRREL2	86	Q6UWL6
PAEVTTTVLVRRDHH	ICAM1	166	P05362
EFHLEDIATERATRH	EEF2K	101	O00418
ADDDDFEPHAIIRHT	MAP4K5	306	Q9Y4K4
NRREESTHDHTIERP	RBM6	311	P78332
SREHRGHSVLPLEEA	TRIM27	121	P14373
PTRKLFEVESVTHHD	SPAG8	371	Q99932
EHTRPDRDNHVTIIR	TLL1	251	O43897
SHVEREDAVHIIPEN	NBPF9	516	P0DPF3
AHHEPERLSRRSEDE	UPF3A	371	Q9H1J1
EFEDEFHSTLRHDRP	PPWD1	561	Q96BP3
EDDPRLHLSHRVEQS	SMG1	1766	Q96Q15
SVHDSVELHLRVPLE	SENP1	381	Q9P0U3
RFVRPSADEFHLDHT	ARHGAP35	41	Q9NRY4
ECARRELHATTPVEH	TET1	2021	Q8NFU7
VTPRHVSRIFVEDRH	CHST8	176	Q9H2A9
DSVPVSLHDERRQRH	RAPGEF2	1161	Q9Y4G8
VPFIEERHRHRFEVN	CTPS2	471	Q9NRF8
AVFHTVVLERHESPD	ZNF160	111	Q9HCG1
REHREHAVLPLDEAV	TRIM7	156	Q9C029
DHEHPESTRISIRQA	SPTBN2	1656	O15020
ERKPSEELVDRIIHH	SULT1E1	211	P49888
RDRFEDHEIEGAHLP	SHANK3	1686	Q9BYB0
YEREPVAERHLHEIQ	STX19	41	Q8N4C7
RHLREHEETEREPAN	ZNF646	1381	O15015
RPERQESAEHEAAHS	SPTBN4	2266	Q9H254
LPDPVEETRHHAEVV	MRPL21	66	Q7Z2W9
HPEIFSTARDILIEH	NT5DC2	86	Q9H857
SIFRVHTRDEPHEYE	ZNF112	376	Q9UJU3
ERDRQPRVTHLFDVH	USP30	176	Q70CQ3
HIRTEHDDERLLKEP	SEMA3E	211	O15041
SRVHAEHNRTPREVE	SEMA3G	766	Q9NS98
IFRCVHRSTHEEAPE	THSD4	641	Q6ZMP0
HLHETEEQPYFRETR	ZNF652	71	Q9Y2D9
VRHTIPEEETHRTQV	UNC13D	161	Q70J99
HPRHVEILGFSEAER	NLRP12	356	P59046