Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	olfactory receptor activity	OR1E2 OR8J3 OR2A5 OR4N2 OR56A1 OR5AK2 OR10S1 OR13F1 OR8U9 OR8G1	1.22e-08	431	41	10	GO:0004984
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR1E2 ADORA3 OR8J3 OR2A5 OR4N2 OR56A1 OR5AK2 OR10S1 OR13F1 OR8U9 OR8G1	1.12e-06	884	41	11	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR1E2 ADORA3 OR8J3 OR2A5 OR4N2 OR56A1 OR5AK2 OR10S1 EPHA2 OR13F1 OR8U9 OR8G1	1.11e-05	1353	41	12	GO:0004888
GeneOntologyMolecularFunction	odorant binding	OR8J3 OR5AK2 OR8U9 OR8G1	1.32e-04	127	41	4	GO:0005549
GeneOntologyMolecularFunction	potassium channel regulator activity	AKT1 WNK4 WNK3	2.18e-04	57	41	3	GO:0015459
GeneOntologyMolecularFunction	potassium channel inhibitor activity	WNK4 WNK3	2.24e-04	11	41	2	GO:0019870
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	MAOA LOXL2	4.85e-04	16	41	2	GO:0016641
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH2 group of donors	MAOA LOXL2	7.63e-04	20	41	2	GO:0016638
GeneOntologyMolecularFunction	protein kinase activity	AKT1 EEF2K AKT3 EPHA2 WNK4 WNK3	1.32e-03	600	41	6	GO:0004672
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	AKT1 EEF2K AKT3 WNK4 WNK3	2.10e-03	446	41	5	GO:0004674
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	AKT1 EEF2K AKT3 EPHA2 WNK4 WNK3	3.06e-03	709	41	6	GO:0016773
GeneOntologyMolecularFunction	ion channel inhibitor activity	WNK4 WNK3	4.37e-03	48	41	2	GO:0008200
GeneOntologyMolecularFunction	kinase activity	AKT1 EEF2K AKT3 EPHA2 WNK4 WNK3	4.41e-03	764	41	6	GO:0016301
GeneOntologyMolecularFunction	ion channel regulator activity	AKT1 WNK4 WNK3	4.46e-03	162	41	3	GO:0099106
GeneOntologyMolecularFunction	channel inhibitor activity	WNK4 WNK3	4.73e-03	50	41	2	GO:0016248
GeneOntologyMolecularFunction	transporter inhibitor activity	WNK4 WNK3	4.92e-03	51	41	2	GO:0141110
GeneOntologyMolecularFunction	channel regulator activity	AKT1 WNK4 WNK3	5.44e-03	174	41	3	GO:0016247
GeneOntologyMolecularFunction	transporter regulator activity	AKT1 WNK4 WNK3	5.70e-03	177	41	3	GO:0141108
GeneOntologyMolecularFunction	protein serine kinase activity	AKT1 AKT3 WNK4 WNK3	6.40e-03	363	41	4	GO:0106310
GeneOntologyMolecularFunction	protein kinase C binding	AKT1 AKT3	8.12e-03	66	41	2	GO:0005080
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR1E2 OR8J3 OR2A5 OR4N2 OR56A1 OR5AK2 OR10S1 OR13F1 OR8U9 OR8G1	7.08e-09	432	40	10	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of smell	OR1E2 OR8J3 OR2A5 OR4N2 OR56A1 OR5AK2 OR10S1 OR13F1 OR8U9 OR8G1	1.42e-08	465	40	10	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR1E2 OR8J3 OR2A5 OR4N2 OR56A1 OR5AK2 OR10S1 OR13F1 OR8U9 OR8G1	2.12e-08	485	40	10	GO:0050907
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR1E2 OR8J3 OR2A5 OR4N2 OR56A1 OR5AK2 OR10S1 OR13F1 OR8U9 OR8G1	4.39e-08	524	40	10	GO:0009593
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR1E2 OR8J3 OR2A5 OR4N2 OR56A1 OR5AK2 OR10S1 OR13F1 OR8U9 OR8G1	6.57e-08	547	40	10	GO:0007606
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR1E2 OR8J3 OR2A5 OR4N2 OR56A1 OR5AK2 OR10S1 OR13F1 OR8U9 OR8G1	1.17e-07	582	40	10	GO:0050906
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	ADCY10 OR1E2 ADORA3 AKT1 OR8J3 OR2A5 OR4N2 OR56A1 OR5AK2 OR10S1 PLPP1 OR13F1 OR8U9 OR8G1	1.72e-07	1395	40	14	GO:0007186
GeneOntologyBiologicalProcess	detection of stimulus	OR1E2 OR8J3 OR2A5 OR4N2 OR56A1 OR5AK2 OR10S1 OR13F1 OR8U9 OR8G1	8.49e-07	722	40	10	GO:0051606
GeneOntologyBiologicalProcess	regulation of cell junction assembly	EEF2K LRTM2 COL16A1 IL1B EPHA2 SIPA1L1	2.69e-05	309	40	6	GO:1901888
GeneOntologyBiologicalProcess	sensory perception	OR1E2 OR8J3 OR2A5 OR4N2 OR56A1 OR5AK2 OR10S1 OR13F1 OR8U9 OR8G1	2.80e-05	1072	40	10	GO:0007600
GeneOntologyBiologicalProcess	negative regulation of pancreatic juice secretion	WNK4 WNK3	3.65e-05	5	40	2	GO:0090188
GeneOntologyBiologicalProcess	regulation of sodium ion transport	AKT1 AKT3 WNK4 WNK3	4.32e-05	101	40	4	GO:0002028
GeneOntologyBiologicalProcess	peptidyl-threonine phosphorylation	ADCY10 AKT1 AKT3 WNK3	7.18e-05	115	40	4	GO:0018107
GeneOntologyBiologicalProcess	positive regulation of sodium ion transport	AKT1 AKT3 WNK3	7.36e-05	42	40	3	GO:0010765
GeneOntologyBiologicalProcess	positive regulation of potassium ion import across plasma membrane	WNK4 WNK3	7.65e-05	7	40	2	GO:1903288
GeneOntologyBiologicalProcess	peptidyl-threonine modification	ADCY10 AKT1 AKT3 WNK3	9.92e-05	125	40	4	GO:0018210
GeneOntologyBiologicalProcess	regulation of protein localization to plasma membrane	AKT1 EPHA2 WNK4 WNK3	1.09e-04	128	40	4	GO:1903076
GeneOntologyBiologicalProcess	female pregnancy	AKT1 FBN2 COL16A1 IL1B INTS1	1.15e-04	249	40	5	GO:0007565
GeneOntologyBiologicalProcess	regulation of glycogen metabolic process	ADCY10 AKT1 PPP1R3B	1.17e-04	49	40	3	GO:0070873
GeneOntologyBiologicalProcess	regulation of potassium ion import	WNK4 WNK3	1.31e-04	9	40	2	GO:1903286
GeneOntologyBiologicalProcess	regulation of pancreatic juice secretion	WNK4 WNK3	1.31e-04	9	40	2	GO:0090186
GeneOntologyBiologicalProcess	positive regulation of cell junction assembly	EEF2K LRTM2 COL16A1 EPHA2	1.37e-04	136	40	4	GO:1901890
GeneOntologyBiologicalProcess	regulation of polysaccharide metabolic process	ADCY10 AKT1 PPP1R3B	1.94e-04	58	40	3	GO:0032881
GeneOntologyBiologicalProcess	multi-organism reproductive process	AKT1 FBN2 COL16A1 IL1B INTS1	2.33e-04	290	40	5	GO:0044703
GeneOntologyBiologicalProcess	multi-multicellular organism process	AKT1 FBN2 COL16A1 IL1B INTS1	2.49e-04	294	40	5	GO:0044706
GeneOntologyBiologicalProcess	secretion by tissue	ADORA3 WNK4 WNK3	2.59e-04	64	40	3	GO:0032941
GeneOntologyBiologicalProcess	regulation of glycogen catabolic process	ADCY10 PPP1R3B	3.29e-04	14	40	2	GO:0005981
GeneOntologyBiologicalProcess	pancreatic juice secretion	WNK4 WNK3	3.29e-04	14	40	2	GO:0030157
GeneOntologyBiologicalProcess	regulation of protein localization to cell periphery	AKT1 EPHA2 WNK4 WNK3	3.30e-04	171	40	4	GO:1904375
GeneOntologyBiologicalProcess	positive regulation of protein localization to plasma membrane	AKT1 EPHA2 WNK3	3.38e-04	70	40	3	GO:1903078
GeneOntologyBiologicalProcess	endothelial cell migration	AKT1 AKT3 PLEKHG5 LOXL2 EPHA2	4.29e-04	331	40	5	GO:0043542
GeneOntologyBiologicalProcess	positive regulation of TOR signaling	AKT1 AKT3 CLEC16A	4.65e-04	78	40	3	GO:0032008
GeneOntologyBiologicalProcess	cell junction organization	AKT1 EEF2K SPG11 LRTM2 COL16A1 IL1B EPHA2 SIPA1L1	4.80e-04	974	40	8	GO:0034330
GeneOntologyBiologicalProcess	positive regulation of protein localization to cell periphery	AKT1 EPHA2 WNK3	5.38e-04	82	40	3	GO:1904377
GeneOntologyBiologicalProcess	spongiotrophoblast layer development	AKT1 BIRC6	5.50e-04	18	40	2	GO:0060712
GeneOntologyBiologicalProcess	negative regulation of digestive system process	WNK4 WNK3	6.82e-04	20	40	2	GO:0060457
GeneOntologyBiologicalProcess	cell junction assembly	EEF2K LRTM2 COL16A1 IL1B EPHA2 SIPA1L1	7.42e-04	569	40	6	GO:0034329
GeneOntologyBiologicalProcess	ameboidal-type cell migration	AKT1 AKT3 FBN2 PLEKHG5 LOXL2 EPHA2	7.98e-04	577	40	6	GO:0001667
GeneOntologyBiologicalProcess	negative regulation of sodium ion transport	WNK4 WNK3	8.27e-04	22	40	2	GO:0010766
GeneOntologyBiologicalProcess	sprouting angiogenesis	AKT1 AKT3 LOXL2 EPHA2	8.52e-04	220	40	4	GO:0002040
GeneOntologyBiologicalProcess	embryo implantation	FBN2 IL1B INTS1	8.78e-04	97	40	3	GO:0007566
GeneOntologyBiologicalProcess	regulation of cell size	ADCY10 AKT1 AKT3 WNK3	9.26e-04	225	40	4	GO:0008361
GeneOntologyBiologicalProcess	glycogen metabolic process	ADCY10 AKT1 PPP1R3B	9.32e-04	99	40	3	GO:0005977
GeneOntologyBiologicalProcess	positive regulation of glycogen metabolic process	ADCY10 AKT1	9.85e-04	24	40	2	GO:0070875
GeneOntologyBiologicalProcess	glucan metabolic process	ADCY10 AKT1 PPP1R3B	9.87e-04	101	40	3	GO:0044042
GeneOntologyBiologicalProcess	cAMP metabolic process	ADCY10 EPHA2	1.07e-03	25	40	2	GO:0046058
GeneOntologyBiologicalProcess	endothelial cell proliferation	AKT1 AKT3 LOXL2 EPHA2	1.09e-03	235	40	4	GO:0001935
GeneOntologyBiologicalProcess	regulation of protein localization to membrane	AKT1 EPHA2 WNK4 WNK3	1.12e-03	237	40	4	GO:1905475
GeneOntologyBiologicalProcess	positive regulation of monooxygenase activity	AKT1 IL1B	1.25e-03	27	40	2	GO:0032770
GeneOntologyBiologicalProcess	negative regulation of extrinsic apoptotic signaling pathway	AKT1 IL1B BIRC6	1.36e-03	113	40	3	GO:2001237
GeneOntologyBiologicalProcess	energy reserve metabolic process	ADCY10 AKT1 PPP1R3B	1.40e-03	114	40	3	GO:0006112
GeneOntologyBiologicalProcess	epithelial cell migration	AKT1 AKT3 PLEKHG5 LOXL2 EPHA2	1.42e-03	432	40	5	GO:0010631
GeneOntologyBiologicalProcess	regulation of nitric-oxide synthase activity	AKT1 IL1B	1.44e-03	29	40	2	GO:0050999
GeneOntologyBiologicalProcess	epithelium migration	AKT1 AKT3 PLEKHG5 LOXL2 EPHA2	1.46e-03	435	40	5	GO:0090132
GeneOntologyBiologicalProcess	tissue migration	AKT1 AKT3 PLEKHG5 LOXL2 EPHA2	1.55e-03	441	40	5	GO:0090130
GeneOntologyBiologicalProcess	negative regulation of protein localization to plasma membrane	WNK4 WNK3	1.65e-03	31	40	2	GO:1903077
GeneOntologyBiologicalProcess	negative regulation of protein localization	AKT1 IL1B WNK4 WNK3	1.65e-03	263	40	4	GO:1903828
GeneOntologyBiologicalProcess	body fluid secretion	ADORA3 WNK4 WNK3	1.66e-03	121	40	3	GO:0007589
GeneOntologyBiologicalProcess	positive regulation of monoatomic ion transport	AKT1 AKT3 WNK4 WNK3	1.72e-03	266	40	4	GO:0043270
GeneOntologyBiologicalProcess	positive regulation of peptidyl-threonine phosphorylation	ADCY10 WNK3	1.75e-03	32	40	2	GO:0010800
GeneOntologyBiologicalProcess	negative regulation of organic acid transport	AKT1 IL1B	1.75e-03	32	40	2	GO:0032891
GeneOntologyBiologicalProcess	cellular response to insulin stimulus	AKT1 EEF2K AKT3 IL1B	1.84e-03	271	40	4	GO:0032869
GeneOntologyBiologicalProcess	negative regulation of protein localization to cell periphery	WNK4 WNK3	1.86e-03	33	40	2	GO:1904376
GeneOntologyBiologicalProcess	polysaccharide metabolic process	ADCY10 AKT1 PPP1R3B	1.86e-03	126	40	3	GO:0005976
GeneOntologyBiologicalProcess	neuron projection organization	ADCY10 EEF2K SIPA1L1	1.91e-03	127	40	3	GO:0106027
GeneOntologyBiologicalProcess	sodium ion transport	AKT1 AKT3 WNK4 WNK3	1.94e-03	275	40	4	GO:0006814
GeneOntologyBiologicalProcess	negative regulation of lipid catabolic process	AKT1 IL1B	1.98e-03	34	40	2	GO:0050995
GeneOntologyBiologicalProcess	positive regulation of protein localization to membrane	AKT1 EPHA2 WNK3	2.04e-03	130	40	3	GO:1905477
GeneOntologyBiologicalProcess	glycogen catabolic process	ADCY10 PPP1R3B	2.10e-03	35	40	2	GO:0005980
GeneOntologyBiologicalProcess	negative regulation of macroautophagy	AKT1 CLEC16A	2.10e-03	35	40	2	GO:0016242
Domain	Olfact_rcpt	OR1E2 OR8J3 OR2A5 OR4N2 OR56A1 OR5AK2 OR10S1 OR13F1 OR8U9 OR8G1	9.51e-09	393	41	10	IPR000725
Domain	GPCR_Rhodpsn_7TM	OR1E2 ADORA3 OR8J3 OR2A5 OR4N2 OR56A1 OR5AK2 OR10S1 OR13F1 OR8U9 OR8G1	1.38e-07	670	41	11	IPR017452
Domain	7tm_1	OR1E2 ADORA3 OR8J3 OR2A5 OR4N2 OR56A1 OR5AK2 OR10S1 OR13F1 OR8U9 OR8G1	1.53e-07	677	41	11	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR1E2 ADORA3 OR8J3 OR2A5 OR4N2 OR56A1 OR5AK2 OR10S1 OR13F1 OR8U9 OR8G1	1.73e-07	685	41	11	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR1E2 ADORA3 OR8J3 OR2A5 OR4N2 OR56A1 OR5AK2 OR10S1 OR13F1 OR8U9 OR8G1	1.88e-07	691	41	11	PS50262
Domain	GPCR_Rhodpsn	OR1E2 ADORA3 OR8J3 OR2A5 OR4N2 OR56A1 OR5AK2 OR10S1 OR13F1 OR8U9 OR8G1	1.91e-07	692	41	11	IPR000276
Domain	Kinase_OSR1/WNK_CCT	WNK4 WNK3	7.01e-05	6	41	2	IPR024678
Domain	OSR1_C	WNK4 WNK3	7.01e-05	6	41	2	PF12202
Domain	Kinase-like_dom	AKT1 EEF2K AKT3 EPHA2 WNK4 WNK3	1.10e-03	542	41	6	IPR011009
Domain	Pkinase_C	AKT1 AKT3	2.98e-03	37	41	2	IPR017892
Domain	PROTEIN_KINASE_ATP	AKT1 AKT3 EPHA2 WNK4 WNK3	3.17e-03	459	41	5	PS00107
Domain	Pkinase_C	AKT1 AKT3	3.83e-03	42	41	2	PF00433
Domain	Prot_kinase_dom	AKT1 AKT3 EPHA2 WNK4 WNK3	4.15e-03	489	41	5	IPR000719
Domain	PROTEIN_KINASE_DOM	AKT1 AKT3 EPHA2 WNK4 WNK3	4.30e-03	493	41	5	PS50011
Domain	AGC-kinase_C	AKT1 AKT3	6.72e-03	56	41	2	IPR000961
Domain	AGC_KINASE_CTER	AKT1 AKT3	6.72e-03	56	41	2	PS51285
Domain	S_TK_X	AKT1 AKT3	6.72e-03	56	41	2	SM00133
Domain	Ser/Thr_kinase_AS	AKT1 AKT3 WNK4 WNK3	7.61e-03	357	41	4	IPR008271
Domain	S_TKc	AKT1 AKT3 WNK4 WNK3	7.76e-03	359	41	4	SM00220
Domain	PROTEIN_KINASE_ST	AKT1 AKT3 WNK4 WNK3	7.99e-03	362	41	4	PS00108
Domain	Pkinase	AKT1 AKT3 WNK4 WNK3	9.52e-03	381	41	4	PF00069
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR1E2 OR8J3 OR2A5 OR4N2 OR56A1 OR5AK2 OR10S1 OR13F1 OR8U9 OR8G1	1.17e-08	417	31	10	M4072
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR1E2 OR8J3 OR2A5 OR4N2 OR56A1 OR5AK2 OR10S1 OR13F1 OR8G1	9.96e-08	389	31	9	M14091
Pathway	REACTOME_SENSORY_PERCEPTION	OR1E2 OR8J3 OR2A5 OR4N2 OR56A1 OR5AK2 OR10S1 OR13F1 OR8U9 OR8G1	6.11e-07	636	31	10	M41834
Pathway	KEGG_MEDICUS_VARIANT_LOSS_OF_NKX3_1_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	4.66e-05	5	31	2	M48999
Pathway	KEGG_MEDICUS_REFERENCE_MAGI_PTEN_SIGNALING_PATHWAY	AKT1 AKT3	6.98e-05	6	31	2	M47523
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PI3K_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	9.76e-05	7	31	2	M47407
Pathway	KEGG_MEDICUS_REFERENCE_ACH_CHRN_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	9.76e-05	7	31	2	M47790
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	1.30e-04	8	31	2	M47399
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	1.30e-04	8	31	2	M47394
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	1.30e-04	8	31	2	M47395
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	1.30e-04	8	31	2	M47404
Pathway	KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	1.30e-04	8	31	2	M47405
Pathway	KEGG_MEDICUS_REFERENCE_P4_PR_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	1.30e-04	8	31	2	M47803
Pathway	REACTOME_RUNX2_REGULATES_GENES_INVOLVED_IN_CELL_MIGRATION	AKT1 AKT3	1.30e-04	8	31	2	M27806
Pathway	KEGG_MEDICUS_VARIANT_TGFA_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	1.30e-04	8	31	2	M47482
Pathway	KEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	1.30e-04	8	31	2	M47498
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_RET_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	1.30e-04	8	31	2	M47715
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	1.67e-04	9	31	2	M47397
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	1.67e-04	9	31	2	M47392
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	1.67e-04	9	31	2	M47391
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	1.67e-04	9	31	2	M47402
Pathway	KEGG_MEDICUS_REFERENCE_MEMBRANE_INITIATED_PROGESTERONE_SIGNALING_PATHWAY	AKT1 AKT3	1.67e-04	9	31	2	M47802
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_MET_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	1.67e-04	9	31	2	M47490
Pathway	KEGG_MEDICUS_REFERENCE_TGFA_EGFR_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	1.67e-04	9	31	2	M47481
Pathway	REACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING	AKT1 AKT3	1.67e-04	9	31	2	MM15666
Pathway	KEGG_MEDICUS_REFERENCE_ICOSLG_ICOS_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	1.67e-04	9	31	2	M47972
Pathway	KEGG_MEDICUS_VARIANT_EGFR_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	2.08e-04	10	31	2	M47400
Pathway	KEGG_MEDICUS_REFERENCE_HGF_MET_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	2.08e-04	10	31	2	M47401
Pathway	KEGG_MEDICUS_REFERENCE_CD80_CD86_CD28_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	2.08e-04	10	31	2	M47615
Pathway	REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_NUCLEUS	AKT1 AKT3	2.08e-04	10	31	2	M27095
Pathway	REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_NUCLEUS	AKT1 AKT3	2.08e-04	10	31	2	MM14778
Pathway	KEGG_MEDICUS_ENV_FACTOR_NICOTINE_NNK_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	2.54e-04	11	31	2	M47797
Pathway	KEGG_MEDICUS_REFERENCE_KITLG_KIT_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	2.54e-04	11	31	2	M47403
Pathway	KEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	2.54e-04	11	31	2	M47406
Pathway	WP_SEROTONIN_TRANSPORTER_ACTIVITY	MAOA IL1B	2.54e-04	11	31	2	M39451
Pathway	KEGG_MEDICUS_REFERENCE_IGF2_IGF1R_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	2.54e-04	11	31	2	M47484
Pathway	KEGG_MEDICUS_REFERENCE_EREG_EGFR_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	2.54e-04	11	31	2	M47499
Pathway	KEGG_MEDICUS_REFERENCE_NRG_ERBB4_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	2.54e-04	11	31	2	M47756
Pathway	KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01339	AKT1 AKT3	2.54e-04	11	31	2	M47791
Pathway	KEGG_MEDICUS_REFERENCE_AREG_EGFR_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	2.54e-04	11	31	2	M47501
Pathway	KEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	3.05e-04	12	31	2	M47393
Pathway	KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01350	AKT1 AKT3	3.05e-04	12	31	2	M47798
Pathway	KEGG_MEDICUS_REFERENCE_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY	AKT1 AKT3	3.05e-04	12	31	2	M47558
Pathway	KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY	AKT1 AKT3	3.05e-04	12	31	2	M47559
Pathway	REACTOME_SARS_COV_2_TARGETS_HOST_INTRACELLULAR_SIGNALLING_AND_REGULATORY_PATHWAYS	AKT1 AKT3	3.05e-04	12	31	2	M45022
Pathway	REACTOME_REGULATION_OF_LOCALIZATION_OF_FOXO_TRANSCRIPTION_FACTORS	AKT1 AKT3	3.05e-04	12	31	2	MM15657
Pathway	REACTOME_REGULATION_OF_LOCALIZATION_OF_FOXO_TRANSCRIPTION_FACTORS	AKT1 AKT3	3.05e-04	12	31	2	M27939
Pathway	REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL	AKT1 AKT3	3.05e-04	12	31	2	MM14777
Pathway	REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING	AKT1 AKT3	3.05e-04	12	31	2	MM14550
Pathway	KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	3.60e-04	13	31	2	M47398
Pathway	KEGG_MEDICUS_REFERENCE_IGF_IGF1R_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	3.60e-04	13	31	2	M47603
Pathway	REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING	AKT1 AKT3	3.60e-04	13	31	2	M549
Pathway	KEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	4.19e-04	14	31	2	M47390
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ASSOCIATION_WITH_CO_FACTORS	AKT1 AKT3	4.19e-04	14	31	2	MM15341
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ASSOCIATION_WITH_CO_FACTORS	AKT1 AKT3	4.19e-04	14	31	2	M27638
Pathway	KEGG_MEDICUS_REFERENCE_IGF_IGFR_PI3K_NFKB_SIGNALING_PATHWAY	AKT1 AKT3	4.19e-04	14	31	2	M47467
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_NFKB_SIGNALING_PATHWAY	AKT1 AKT3	4.19e-04	14	31	2	M47536
Pathway	REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL	AKT1 AKT3	4.19e-04	14	31	2	M3862
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	4.83e-04	15	31	2	M47389
Pathway	KEGG_MEDICUS_REFERENCE_RELN_VLDLR_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	4.83e-04	15	31	2	M47663
Pathway	REACTOME_ACTIVATION_OF_BAD_AND_TRANSLOCATION_TO_MITOCHONDRIA	AKT1 AKT3	4.83e-04	15	31	2	M26902
Pathway	KEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	4.83e-04	15	31	2	M47475
Pathway	WP_RIOK1_AND_RIOK2_IN_EGFR_AND_PI3KMEDIATED_TUMORIGENESIS	AKT1 AKT3	4.83e-04	15	31	2	M48306
Pathway	KEGG_MEDICUS_REFERENCE_BCR_BCAP_CD19_PI3K_SIGNALING_PATHWAY	AKT1 AKT3	4.83e-04	15	31	2	M47971
Pathway	WP_INVOLVEMENT_OF_SECRETASE_IN_NEURODEGENERATIVE_DISEASES	AKT1 AKT3	6.24e-04	17	31	2	M48086
Pathway	SA_PTEN_PATHWAY	AKT1 AKT3	6.24e-04	17	31	2	M12771
Pathway	SA_TRKA_RECEPTOR	AKT1 AKT3	6.24e-04	17	31	2	M18895
Pathway	WP_TGFBETA_SIGNALING_IN_THYROID_CELLS_FOR_EPITHELIALMESENCHYMAL_TRANSITION	AKT1 AKT3	7.82e-04	19	31	2	M39370
Pathway	KEGG_MEDICUS_REFERENCE_PP2A_AKT_SIGNALING_PATHWAY	AKT1 AKT3	7.82e-04	19	31	2	M47525
Pathway	KEGG_MEDICUS_REFERENCE_GF_RTK_PI3K_SIGNALING_PATHWAY	AKT1 AKT3 EPHA2	7.85e-04	83	31	3	M47961
Pathway	KEGG_APOPTOSIS	AKT1 AKT3 IL1B	9.01e-04	87	31	3	M8492
Pathway	REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS	AKT1 AKT3	9.58e-04	21	31	2	M14966
Pathway	REACTOME_CTLA4_INHIBITORY_SIGNALING	AKT1 AKT3	9.58e-04	21	31	2	M5876
Pathway	REACTOME_CTLA4_INHIBITORY_SIGNALING	AKT1 AKT3	9.58e-04	21	31	2	MM14996
Pathway	KEGG_MEDICUS_REFERENCE_GF_RTK_RAS_PI3K_SIGNALING_PATHWAY	AKT1 AKT3 EPHA2	9.62e-04	89	31	3	M47963
Pathway	REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING	AKT1 AKT3	1.05e-03	22	31	2	M13897
Pathway	REACTOME_FOXO_MEDIATED_TRANSCRIPTION	AKT1 AKT3	1.05e-03	22	31	2	MM15656
Pathway	KEGG_MEDICUS_REFERENCE_CD80_CD86_CTLA4_PP2A_SIGNALING_PATHWAY	AKT1 AKT3	1.05e-03	22	31	2	M47919
Pathway	WP_GPCRS_OTHER	ADORA3 OR2A5 OR8G1	1.09e-03	93	31	3	M39629
Pathway	WP_SIGNAL_TRANSDUCTION_OF_S1P_RECEPTOR	AKT1 AKT3	1.15e-03	23	31	2	MM15952
Pathway	WP_SILDENAFIL_TREATMENT	AKT1 AKT3	1.15e-03	23	31	2	M46455
Pathway	REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING	AKT1 AKT3	1.15e-03	23	31	2	MM14993
Pathway	KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS	AKT1 AKT3 PLPP1	1.20e-03	96	31	3	M16121
Pathway	WP_GPCRS_OTHER	OR1E2 ADORA3 OR8G1	1.20e-03	96	31	3	MM15939
Pathway	REACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING	AKT1 AKT3	1.25e-03	24	31	2	M27952
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_AKT_SIGNALING_PATHWAY	AKT1 AKT3	1.25e-03	24	31	2	M47460
Pathway	WP_REGULATION_OF_APOPTOSIS_BY_PARATHYROID_HORMONERELATED_PROTEIN	AKT1 AKT3	1.36e-03	25	31	2	M39533
Pathway	WP_RELATIONSHIP_BETWEEN_INFLAMMATION_COX2_AND_EGFR	AKT1 AKT3	1.36e-03	25	31	2	M39794
Pathway	WP_S1P_RECEPTOR_SIGNAL_TRANSDUCTION	AKT1 AKT3	1.36e-03	25	31	2	M39384
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA	AKT1 AKT3	1.36e-03	25	31	2	M14301
Pathway	KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY	AKT1 AKT3 IL1B	1.43e-03	102	31	3	M3261
Pathway	WP_TOLLLIKE_RECEPTOR_SIGNALING	AKT1 AKT3 IL1B	1.47e-03	103	31	3	M39434
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA	AKT1 AKT3	1.47e-03	26	31	2	MM15017
Pathway	REACTOME_CONSTITUTIVE_SIGNALING_BY_AKT1_E17K_IN_CANCER	AKT1 AKT3	1.47e-03	26	31	2	M27558
Pathway	REACTOME_DOWNREGULATION_OF_ERBB2_SIGNALING	AKT1 AKT3	1.47e-03	26	31	2	MM15501
Pathway	WP_GROWTH_FACTORS_AND_HORMONES_IN_BETA_CELL_PROLIFERATION	AKT1 AKT3	1.47e-03	26	31	2	M48092
Pathway	KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_PI3K_AKT_SIGNALING_PATHWAY	AKT1 AKT3	1.47e-03	26	31	2	M47456
Pathway	REACTOME_VEGFR2_MEDIATED_VASCULAR_PERMEABILITY	AKT1 AKT3	1.59e-03	27	31	2	M27422
Pathway	SIG_IL4RECEPTOR_IN_B_LYPHOCYTES	AKT1 AKT3	1.59e-03	27	31	2	M1718
Pathway	REACTOME_INTERLEUKIN_4_AND_INTERLEUKIN_13_SIGNALING	AKT1 MAOA IL1B	1.82e-03	111	31	3	M27609
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR1E2 OR8J3 OR2A5 OR4N2 OR5AK2 OR10S1 OR13F1 OR8G1	5.54e-09	340	41	8	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR1E2 OR8J3 OR2A5 OR4N2 OR5AK2 OR10S1 OR13F1 OR8G1	5.54e-09	340	41	8	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR1E2 OR8J3 OR2A5 OR4N2 OR5AK2 OR10S1 OR13F1 OR8G1	5.94e-09	343	41	8	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR1E2 OR8J3 OR2A5 OR4N2 OR5AK2 OR10S1 OR13F1 OR8G1	6.35e-09	346	41	8	14611657
Pubmed	Serum and glucocorticoid-induced kinase (SGK) 1 and the epithelial sodium channel are regulated by multiple with no lysine (WNK) family members.	AKT1 WNK4 WNK3	5.30e-08	7	41	3	20525693
Pubmed	The human olfactory receptor gene family.	OR1E2 OR8J3 OR4N2 OR56A1 OR5AK2 OR10S1 OR13F1 OR8G1	1.98e-07	541	41	8	14983052
Pubmed	WNKs are potassium-sensitive kinases.	WNK4 WNK3	1.36e-06	2	41	2	33439774
Pubmed	AKT isoforms 1 and 3 regulate basal and epidermal growth factor-stimulated SGHPL-5 trophoblast cell migration in humans.	AKT1 AKT3	1.36e-06	2	41	2	23303682
Pubmed	Akt3 deletion in mice impairs spatial cognition and hippocampal CA1 long long-term potentiation through downregulation of mTOR.	AKT1 AKT3	1.36e-06	2	41	2	30053339
Pubmed	Akt1 and akt3 exert opposing roles in the regulation of vascular tumor growth.	AKT1 AKT3	1.36e-06	2	41	2	25388284
Pubmed	Rarity of AKT1 and AKT3 E17K mutations in squamous cell carcinoma of lung.	AKT1 AKT3	1.36e-06	2	41	2	20980808
Pubmed	Impaired Spatial Learning is Associated with Disrupted Integrity of the White Matter in Akt3 Knockout Mice.	AKT1 AKT3	1.36e-06	2	41	2	27671373
Pubmed	Distinct functional roles of Akt isoforms for proliferation, survival, migration and EGF-mediated signalling in lung cancer derived disseminated tumor cells.	AKT1 AKT3	1.36e-06	2	41	2	21777670
Pubmed	EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties.	AKT1 EPHA2	1.36e-06	2	41	2	24488013
Pubmed	Regulatory role of PI3K-protein kinase B on the release of interleukin-1β in peritoneal macrophages from the ascites of cirrhotic patients.	AKT1 IL1B	1.36e-06	2	41	2	25080058
Pubmed	WNK3 and WNK4 amino-terminal domain defines their effect on the renal Na+-Cl- cotransporter.	WNK4 WNK3	1.36e-06	2	41	2	18701621
Pubmed	Effects of the Ras homolog Rhes on Akt/protein kinase B and glycogen synthase kinase 3 phosphorylation in striatum.	AKT1 RASD2	1.36e-06	2	41	2	23380502
Pubmed	Deletion of PKBalpha/Akt1 affects thymic development.	AKT1 AKT3	4.06e-06	3	41	2	17912369
Pubmed	Differential activation of AKT isoforms by growth factors in human myotubes.	AKT1 AKT3	4.06e-06	3	41	2	37879895
Pubmed	Differential prognostic values of the three AKT isoforms in acute myeloid leukemia.	AKT1 AKT3	4.06e-06	3	41	2	38528080
Pubmed	The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex.	WNK4 WNK3	4.06e-06	3	41	2	17975670
Pubmed	Increased level of phosphorylated akt measured by chemiluminescence-linked immunosorbent assay is a predictor of poor prognosis in primary breast cancer overexpressing ErbB-2.	AKT1 AKT3	4.06e-06	3	41	2	15987444
Pubmed	Role of Akt isoforms in IGF-I-mediated signaling and survival in myoblasts.	AKT1 AKT3	4.06e-06	3	41	2	19703413
Pubmed	MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells.	AKT1 AKT3	4.06e-06	3	41	2	19825827
Pubmed	Kinetic mechanism of AKT/PKB enzyme family.	AKT1 AKT3	4.06e-06	3	41	2	16540465
Pubmed	Akt3 deficiency in macrophages promotes foam cell formation and atherosclerosis in mice.	AKT1 AKT3	4.06e-06	3	41	2	22632897
Pubmed	Molecular alterations in AKT1, AKT2 and AKT3 detected in breast and prostatic cancer by FISH.	AKT1 AKT3	4.06e-06	3	41	2	20102399
Pubmed	Distinct roles of the three Akt isoforms in lactogenic differentiation and involution.	AKT1 AKT3	4.06e-06	3	41	2	18561256
Pubmed	EphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with Akt.	AKT1 EPHA2	4.06e-06	3	41	2	19573808
Pubmed	Differential effects of Akt isoforms on somatic cell reprogramming.	AKT1 AKT3	4.06e-06	3	41	2	25037569
Pubmed	All Three AKT Isoforms Can Upregulate Oxygen Metabolism and Lactate Production in Human Hepatocellular Carcinoma Cell Lines.	AKT1 AKT3	4.06e-06	3	41	2	38396845
Pubmed	AKT isoforms have distinct hippocampal expression and roles in synaptic plasticity.	AKT1 AKT3	4.06e-06	3	41	2	29173281
Pubmed	Akt/PKB isoforms expression in the human lumbar herniated disc: correlation with clinical and MRI findings.	AKT1 AKT3	4.06e-06	3	41	2	21590431
Pubmed	Protein kinase Akt activity in human thyroid tumors.	AKT1 AKT3	4.06e-06	3	41	2	29235817
Pubmed	Immunohistological Examination of AKT Isoforms in the Brain: Cell-Type Specificity That May Underlie AKT's Role in Complex Brain Disorders and Neurological Disease.	AKT1 AKT3	4.06e-06	3	41	2	34296180
Pubmed	Sex differences in the mechanism of Met5-enkephalin-induced cardioprotection: role of PI3K/Akt.	AKT1 AKT3	4.06e-06	3	41	2	17982014
Pubmed	Opposing functions of Akt isoforms in lung tumor initiation and progression.	AKT1 AKT3	4.06e-06	3	41	2	24722238
Pubmed	The AKT genes and their roles in various disorders.	AKT1 AKT3	4.06e-06	3	41	2	24039187
Pubmed	Life with a single isoform of Akt: mice lacking Akt2 and Akt3 are viable but display impaired glucose homeostasis and growth deficiencies.	AKT1 AKT3	4.06e-06	3	41	2	16923958
Pubmed	Nonredundant role of Akt2 for neuroprotection of rod photoreceptor cells from light-induced cell death.	AKT1 AKT3	4.06e-06	3	41	2	17202487
Pubmed	Specific Targeting of Akt Kinase Isoforms: Taking the Precise Path for Prevention and Treatment of Cancer.	AKT1 AKT3	4.06e-06	3	41	2	26953242
Pubmed	Identification and quantification of AKT isoforms and phosphoforms in breast cancer using a novel nanofluidic immunoassay.	AKT1 AKT3	4.06e-06	3	41	2	23929892
Pubmed	Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer.	AKT1 AKT3	4.06e-06	3	41	2	19805051
Pubmed	Signalling specificity in the Akt pathway in breast cancer.	AKT1 AKT3	4.06e-06	3	41	2	25233414
Pubmed	Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation.	AKT1 AKT3	4.06e-06	3	41	2	21555366
Pubmed	Specific Akt Family Members Impair Stress-Mediated Transactivation of Viral Promoters and Enhance Neuronal Differentiation: Important Functions for Maintaining Latency.	AKT1 AKT3	4.06e-06	3	41	2	32796067
Pubmed	All Akt isoforms (Akt1, Akt2, Akt3) are involved in normal hearing, but only Akt2 and Akt3 are involved in auditory hair cell survival in the mammalian inner ear.	AKT1 AKT3	4.06e-06	3	41	2	25811375
Pubmed	Akt/Protein kinase B is required for lymphatic network formation, remodeling, and valve development.	AKT1 AKT3	4.06e-06	3	41	2	20724596
Pubmed	Akt Regulates Axon Wrapping and Myelin Sheath Thickness in the PNS.	AKT1 AKT3	4.06e-06	3	41	2	27098694
Pubmed	Optogenetic activation reveals distinct roles of PIP3 and Akt in adipocyte insulin action.	AKT1 AKT3	4.06e-06	3	41	2	27076519
Pubmed	Variation in Akt protein kinases in human populations.	AKT1 AKT3	4.06e-06	3	41	2	28931550
Pubmed	Cellular survival: a play in three Akts.	AKT1 AKT3	4.06e-06	3	41	2	10579998
Pubmed	Key signalling nodes in mammary gland development and cancer. Signalling downstream of PI3 kinase in mammary epithelium: a play in 3 Akts.	AKT1 AKT3	4.06e-06	3	41	2	20398329
Pubmed	Isoform-specific roles for AKT in affective behavior, spatial memory, and extinction related to psychiatric disorders.	AKT1 AKT3	4.06e-06	3	41	2	33325370
Pubmed	The Akt isoforms are present at distinct subcellular locations.	AKT1 AKT3	4.06e-06	3	41	2	20018949
Pubmed	Elevated levels of IL-1beta in Fanconi anaemia group A patients due to a constitutively active phosphoinositide 3-kinase-Akt pathway are capable of promoting tumour cell proliferation.	AKT1 IL1B	4.06e-06	3	41	2	19473116
Pubmed	Identification of AKT kinases as unfavorable prognostic factors for hepatocellular carcinoma by a combination of expression profile, interaction network analysis and clinical validation.	AKT1 AKT3	4.06e-06	3	41	2	24247267
Pubmed	Dissociation of gemcitabine sensitivity and protein kinase B signaling in pancreatic ductal adenocarcinoma models.	AKT1 AKT3	4.06e-06	3	41	2	17895832
Pubmed	Caspase-3-mediated cleavage of Akt: involvement of non-consensus sites and influence of phosphorylation.	AKT1 AKT3	4.06e-06	3	41	2	17544405
Pubmed	Sucrose, But Not Glucose, Blocks IL1-β-Induced Inflammatory Response in Human Chondrocytes by Inducing Autophagy via AKT/mTOR Pathway.	AKT1 IL1B	4.06e-06	3	41	2	27669541
Pubmed	Molecular cloning, expression and characterization of the human serine/threonine kinase Akt-3.	AKT1 AKT3	4.06e-06	3	41	2	10491192
Pubmed	Valproic acid induces monoamine oxidase A via Akt/forkhead box O1 activation.	AKT1 MAOA	4.06e-06	3	41	2	21775495
Pubmed	Striatum specific protein, Rhes regulates AKT pathway.	AKT1 RASD2	4.06e-06	3	41	2	22683505
Pubmed	Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/neu and MMTV-polyoma middle T transgenic mice.	AKT1 AKT3	4.06e-06	3	41	2	17210696
Pubmed	Role for Akt3/protein kinase Bgamma in attainment of normal brain size.	AKT1 AKT3	4.06e-06	3	41	2	15713641
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR1E2 OR8J3 OR2A5 OR10S1 OR8G1	5.89e-06	219	41	5	12213199
Pubmed	Differential expression of gastric MUC5AC in colonic epithelial cells: TFF3-wired IL1 β/Akt crosstalk-induced mucosal immune response against Shigella dysenteriae infection.	AKT1 IL1B	8.12e-06	4	41	2	22389405
Pubmed	Protein kinase Akt2/PKBβ is involved in blastomere proliferation of preimplantation mouse embryos.	AKT1 AKT3	8.12e-06	4	41	2	31552693
Pubmed	WNK kinases, a novel protein kinase subfamily in multi-cellular organisms.	WNK4 WNK3	8.12e-06	4	41	2	11571656
Pubmed	Differential effects of protein kinase B/Akt isoforms on glucose homeostasis and islet mass.	AKT1 AKT3	8.12e-06	4	41	2	19933838
Pubmed	Human hypertension caused by mutations in WNK kinases.	WNK4 WNK3	8.12e-06	4	41	2	11498583
Pubmed	Akt1 deletion prevents lung tumorigenesis by mutant K-ras.	AKT1 AKT3	8.12e-06	4	41	2	21242979
Pubmed	A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells.	AKT1 IL1B	8.12e-06	4	41	2	10748004
Pubmed	Impaired degradation of WNK by Akt and PKA phosphorylation of KLHL3.	AKT1 WNK4	8.12e-06	4	41	2	26435498
Pubmed	SLC26A9 is a Cl(-) channel regulated by the WNK kinases.	WNK4 WNK3	8.12e-06	4	41	2	17673510
Pubmed	Photoreceptor Neuroprotection: Regulation of Akt Activation Through Serine/Threonine Phosphatases, PHLPP and PHLPPL.	AKT1 AKT3	8.12e-06	4	41	2	26427440
Pubmed	Activator protein-1 has an essential role in pancreatic cancer cells and is regulated by a novel Akt-mediated mechanism.	AKT1 AKT3	8.12e-06	4	41	2	19435822
Pubmed	Nonredundant functions for Akt isoforms in astrocyte growth and gliomagenesis in an orthotopic transplantation model.	AKT1 AKT3	8.12e-06	4	41	2	21507933
Pubmed	Axon morphogenesis and maintenance require an evolutionary conserved safeguard function of Wnk kinases antagonizing Sarm and Axed.	WNK4 WNK3	8.12e-06	4	41	2	34384519
Pubmed	S6K inhibition renders cardiac protection against myocardial infarction through PDK1 phosphorylation of Akt.	AKT1 AKT3	8.12e-06	4	41	2	21906027
Pubmed	Conditional inactivation of Akt three isoforms causes tau hyperphosphorylation in the brain.	AKT1 AKT3	8.12e-06	4	41	2	26227811
Pubmed	Casein kinase 2-interacting protein-1, a novel Akt pleckstrin homology domain-interacting protein, down-regulates PI3K/Akt signaling and suppresses tumor growth in vivo.	AKT1 AKT3	8.12e-06	4	41	2	17942896
Pubmed	Specific beta1 integrin site selectively regulates Akt/protein kinase B signaling via local activation of protein phosphatase 2A.	AKT1 PLPP1	8.12e-06	4	41	2	12637511
Pubmed	Loss of 2 Akt (Protein Kinase B) Isoforms in Hematopoietic Cells Diminished Monocyte and Macrophage Survival and Reduces Atherosclerosis in Ldl Receptor-Null Mice.	AKT1 AKT3	8.12e-06	4	41	2	30567482
Pubmed	Human immunodeficiency virus type 1 induces lytic cycle replication of Kaposi's-sarcoma-associated herpesvirus: role of Ras/c-Raf/MEK1/2, PI3K/AKT, and NF-κB signaling pathways.	AKT1 AKT3	8.12e-06	4	41	2	21763505
Pubmed	GLUT5 regulation by AKT1/3-miR-125b-5p downregulation induces migratory activity and drug resistance in TLR-modified colorectal cancer cells.	AKT1 AKT3	8.12e-06	4	41	2	32649737
Pubmed	The E3 ligase TTC3 facilitates ubiquitination and degradation of phosphorylated Akt.	AKT1 AKT3	1.35e-05	5	41	2	20059950
Pubmed	Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha.	AKT1 AKT3	1.35e-05	5	41	2	9512493
Pubmed	Akt1-Inhibitor of DNA binding2 is essential for growth cone formation and axon growth and promotes central nervous system axon regeneration.	AKT1 AKT3	1.35e-05	5	41	2	27938661
Pubmed	Structural and biochemical characterization of the KLHL3-WNK kinase interaction important in blood pressure regulation.	WNK4 WNK3	1.35e-05	5	41	2	24641320
Pubmed	PI3K-Akt signaling pathway upregulates hepatitis C virus RNA translation through the activation of SREBPs.	AKT1 AKT3	1.35e-05	5	41	2	26855332
Pubmed	Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition.	AKT1 AKT3	1.35e-05	5	41	2	17442925
Pubmed	ADP-stimulated activation of Akt during integrin outside-in signaling promotes platelet spreading by inhibiting glycogen synthase kinase-3β.	AKT1 AKT3	1.35e-05	5	41	2	22814751
Pubmed	Leptin deficiency and beta-cell dysfunction underlie type 2 diabetes in compound Akt knockout mice.	AKT1 AKT3	1.35e-05	5	41	2	19289493
Pubmed	Platelet-derived growth factor protects neurons against gp120-mediated toxicity.	AKT1 AKT3	1.35e-05	5	41	2	18300076
Pubmed	The activity of the anti-apoptotic fragment generated by the caspase-3/p120 RasGAP stress-sensing module displays strict Akt isoform specificity.	AKT1 AKT3	1.35e-05	5	41	2	25246356
Pubmed	Brown fat organogenesis and maintenance requires AKT1 and AKT2.	AKT1 AKT3	1.35e-05	5	41	2	30833219
Pubmed	The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region.	AKT1 AKT3	1.35e-05	5	41	2	36640312
Pubmed	A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death.	AKT1 AKT3	1.35e-05	5	41	2	15579468
Pubmed	Spontaneous Hepatocellular Carcinoma after the Combined Deletion of Akt Isoforms.	AKT1 AKT3	1.35e-05	5	41	2	26996309
GeneFamily	Olfactory receptors, family 8	OR8J3 OR8U9 OR8G1	6.50e-05	49	29	3	155
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	AKT1 AKT3 PLEKHG5	4.28e-03	206	29	3	682
Coexpression	SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP	PAM ADORA3 AKT3 FBN2 COL16A1 LOXL2	1.47e-05	352	40	6	M17471
ToppCell	5'-Adult-Distal_Rectal-Epithelial-goblet-BEST2+_Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FCGBP COL16A1 PLEKHG5 WNK4 RASD2	4.95e-07	175	40	5	019ea30ac55748463d7917abf3d3f0e804189bfd
ToppCell	5'-Adult-Distal_Rectal-Epithelial-goblet\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FCGBP COL16A1 PLEKHG5 WNK4 RASD2	5.39e-07	178	40	5	9099b47e0756d6a1b7ba1c6aa7b47c5425f649e0
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL16A1 CLEC16A LOXL2 RASD2	1.77e-05	174	40	4	c529f3674b784f872f4387ffdeb46aecb619976b
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-chondrocyte\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PAM COL16A1 LOXL2 WNK4	2.11e-05	182	40	4	ed487f3a774812caa2903a646b60c86edcc1e65e
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	EEF2K AKT3 MAOA AADACL2	2.30e-05	186	40	4	6259f0f2d5bc863782d09a901d6be2f387d1f074
ToppCell	Fibroblast-C\|World / shred on cell class and cell subclass (v4)	PAM FBN2 COL16A1 LOXL2	2.45e-05	189	40	4	58e0400fbab5a0755504275aef5cf7986149abab
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAM FBN2 COL16A1 LOXL2	2.50e-05	190	40	4	947807863a9b247c301c6cf63d6fd5a2c8018e66
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAM FBN2 COL16A1 LOXL2	2.55e-05	191	40	4	db4943dd19207663fb9e27f8940fa4b06a933625
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAM FBN2 COL16A1 LOXL2	2.55e-05	191	40	4	75d2197076a9dfc868e8baf95bd4c5e44f438e3e
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAM FBN2 COL16A1 LOXL2	2.55e-05	191	40	4	4b50fdd310701251e64e16cd2d07ce03dbfd3e3e
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAM FBN2 COL16A1 LOXL2	2.60e-05	192	40	4	ad48c941a3ddfd9a5146bafc2209da577bb50531
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAM FBN2 COL16A1 LOXL2	2.60e-05	192	40	4	19b94f254d51b9bda3d9b7c6f85e27ecb58409c8
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-secretory_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKT1 FCGBP PLPP1 RASD2	2.66e-05	193	40	4	64bcdbb422f8da6fc3275e82f6aaf562f546a180
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKT1 FCGBP PLPP1 RASD2	2.66e-05	193	40	4	5a92697430f16c49e19a5f727d289d7bd1ece31c
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAM FBN2 COL16A1 LOXL2	2.88e-05	197	40	4	26475b9e4d6bfc0ae818dea13d139888ed7e92f1
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAM FBN2 COL16A1 LOXL2	2.88e-05	197	40	4	155e63b33302a87393ace699b2f6d73abe9c5763
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-B_(Myofibroblast)\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	PAM FBN2 COL16A1 LOXL2	2.94e-05	198	40	4	196257c4420ac801ed9fbb444f11718adb7560ae
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAM FBN2 COL16A1 LOXL2	2.94e-05	198	40	4	a699b365d3b6149f13f02b2e2ae9b6fdce761848
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAM FBN2 COL16A1 LOXL2	2.94e-05	198	40	4	a4005a49cf6709b543994ceb51ecd5dc46197fa9
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMTC2 COL16A1 PLPP1 LOXL2	3.00e-05	199	40	4	08bdcabc3fce787578a8eb66fc8412b0974fa6cc
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN2 COL16A1 PLPP1 LOXL2	3.00e-05	199	40	4	84545ced0c792bc77980a50d65e484eab648d47e
ToppCell	(02)_MMP9/10+-(1)_GFP\|(02)_MMP9/10+ / shred by cell type by condition	AKT1 IL1B LOXL2 EPHA2	3.00e-05	199	40	4	448ba982be804007f991d469eca9d885b21ae499
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMTC2 FBN2 COL16A1 PLPP1	3.00e-05	199	40	4	8d71e1fc92ee24deedf23fbb1a85a7fba0d8d436
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMTC2 FBN2 COL16A1 PLPP1	3.00e-05	199	40	4	49690494270981eec5b5261c59e0545dff90cc21
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN2 COL16A1 PLPP1 LOXL2	3.05e-05	200	40	4	3dacd0afe69bc16bb33336ea9ea99a9cd47731d9
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN2 COL16A1 PLPP1 LOXL2	3.05e-05	200	40	4	ac8a5d71acd4d401995babd233f0d3738e8ad2a5
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Basaloid_Squamous_Cell_Carcinoma-5\|TCGA-Lung / Sample_Type by Project: Shred V9	ADCY10 KYAT1 OR13F1	8.51e-05	95	40	3	25871a75ee78cf78143f91fac52ef7ae58679f1e
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAOA PPP1R3B RASD2	2.20e-04	131	40	3	7346d4121063cbe100505c81a5f0bc612150064a
ToppCell	10x5'-Lung-Myeloid_Mac-Intestinal_macrophages\|Lung / Manually curated celltypes from each tissue	ADORA3 FBN2 FCGBP	2.73e-04	141	40	3	7671d300b1722711fd2d8034b96a3aa7e3ccb560
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-6\|TCGA-Cervix / Sample_Type by Project: Shred V9	FBN2 IL1B LOXL2	2.85e-04	143	40	3	10955b54e4a87d035093a2756291ef1d6a14ab63
ToppCell	Substantia_nigra-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ADORA3 IL1B PPP1R3B	3.28e-04	150	40	3	edbc1d29d213bf5908592135700e0d80e123c923
ToppCell	Substantia_nigra-Hematopoietic-MICROGLIA\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ADORA3 IL1B PPP1R3B	3.28e-04	150	40	3	d44c02402e59a45e40b8fffbe71284032b5e7c92
ToppCell	Substantia_nigra-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ADORA3 IL1B PPP1R3B	3.28e-04	150	40	3	01c526e1e3007e71e416c317549fddd2919b14e9
ToppCell	Substantia_nigra-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ADORA3 IL1B PPP1R3B	3.28e-04	150	40	3	b7f5bf9af7ed50aad4da1c71d37b8b9709e6ce85
ToppCell	Substantia_nigra-Hematopoietic-MICROGLIA-MI2(C1qb)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ADORA3 IL1B PPP1R3B	3.28e-04	150	40	3	e020dbcf85c0ba7ad667b8bbeb6bbcfc135c9bb7
ToppCell	facs-Trachea-nan-24m-Myeloid-granulocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADORA3 IL1B PPP1R3B	3.34e-04	151	40	3	26fd55efb647c41436416d45952ee97b050e632c
ToppCell	PND01-Immune-Immune_Myeloid-DC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADORA3 IL1B FBXO42	3.41e-04	152	40	3	c8faa83dcaddb2ce2bb890f90dd8e676f7dcb1b3
ToppCell	PND01-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADORA3 IL1B FBXO42	3.41e-04	152	40	3	c3f00beb8b6fde99263d5ed6bbe3c2415d02f91d
ToppCell	PND01-Immune-Immune_Myeloid-DC-cDC2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADORA3 IL1B FBXO42	3.41e-04	152	40	3	cefc0ab592e99badf145fb95adf9906cb81be81c
ToppCell	facs-Trachea-24m-Hematologic-myeloid-granulocyte\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADORA3 IL1B PPP1R3B	3.75e-04	157	40	3	188d2f85babcd4eefe20e7a392d851b2e1185bab
ToppCell	367C-Fibroblasts-Fibroblast-F\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ADCY10 LOXL2 AADACL2	4.03e-04	161	40	3	c61283c301a87bb802f6f8ce79c26067032dd7d9
ToppCell	367C-Fibroblasts-Fibroblast-F-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ADCY10 LOXL2 AADACL2	4.03e-04	161	40	3	9864d8b0929dacf4be7a4e97d2527ac3120ea264
ToppCell	PND01-03-samps\|World / Age Group, Lineage, Cell class and subclass	IL1B PLPP1 BIRC6	4.03e-04	161	40	3	1973b112d8d67aacc02751797d0148e7b53bfa66
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|Fibroblasts / Location, Cell class and cell subclass	FBN2 COL16A1 LOXL2	4.25e-04	164	40	3	9b4a6007abae992db871d9f6f731d5af724de30d
ToppCell	droplet-Fat-Scat-21m\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMTC2 FBN2 FCGBP	4.33e-04	165	40	3	3f0c2486ea357d10dad0b703cf75cc29bdd5b5cf
ToppCell	facs-Marrow-T_cells-18m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADORA3 PLEKHG5 RASD2	4.41e-04	166	40	3	c22b0f3bf990d94b615a3aacee5de548da2db628
ToppCell	facs-Marrow-T_cells-18m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADORA3 PLEKHG5 RASD2	4.41e-04	166	40	3	0975fc165bcc7e85f053d9d0244fffe407c23571
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.1.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FCGBP IL1B WNK3	4.49e-04	167	40	3	8fede587572d465cb63f7828141a574185bbb819
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ADORA3 FCGBP IL1B	4.64e-04	169	40	3	0867528101767fc65e93b3561480bf830c50368d
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-CD1c+_DCs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	LRTM2 IL1B LOXL2	4.72e-04	170	40	3	403b6b749d70d845838dcda7daf99971b50792a2
ToppCell	facs-Marrow-KLS-18m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADORA3 TMTC2 PLPP1	4.89e-04	172	40	3	979fd7b435f59b8a4d290a809cf76147d4c63d48
ToppCell	facs-Marrow-KLS-18m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADORA3 TMTC2 PLPP1	4.89e-04	172	40	3	f4d7f416802218ce56408fa4cb8a555d846bc85b
ToppCell	367C-Lymphocytic-ILC-ILC-2\|367C / Donor, Lineage, Cell class and subclass (all cells)	PLEKHG5 CLEC16A KYAT1	4.97e-04	173	40	3	0451450605521fecb27a958628870d268adfb023
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAM COL16A1 BIRC6	5.14e-04	175	40	3	8b498eea1ec1c1f27b171025c3d08adf3687bafc
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAM COL16A1 BIRC6	5.14e-04	175	40	3	a5db428b078938627e61b7e944c1e0c1d61ac2da
ToppCell	5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FCGBP PPP1R3B WNK4	5.31e-04	177	40	3	e1e45956887371b1c18f1eb479dd930031497520
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FBN2 IL1B WNK3	5.40e-04	178	40	3	c90e9048fc786ba8559972ae25c25ecab4bc1b7c
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FBN2 IL1B WNK3	5.40e-04	178	40	3	9e426ce23a4a33b91d139ad85685cf8483bcd01a
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet-BEST2+_Goblet_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FCGBP WNK4 RASD2	5.49e-04	179	40	3	c833ded1f9e87be2ba2037820d92a389560b711c
ToppCell	ILEUM-non-inflamed-(8)_Fibroblast-(8)_Activated_fibroblasts\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CLEC16A LOXL2 EPHA2	5.49e-04	179	40	3	5787ffba96918db80256ced076a455a84ba01384
ToppCell	367C-Lymphocytic-ILC-ILC-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PLEKHG5 CLEC16A KYAT1	5.49e-04	179	40	3	5aa8465e943b6b666c7f8b1937fcc3764bfe91f6
ToppCell	10x5'v1-week_17-19-Myeloid_macrophage-stroma-monocytoid_macrophage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ADORA3 FCGBP PLEKHG5	5.58e-04	180	40	3	ba4c1fb55e8f1095bea6968417fefcf5f700926b
ToppCell	(05)_Ciliated-(4)_1wkpi\|(05)_Ciliated / shred by cell type and Timepoint	PAM LOXL2 SIPA1L1	5.58e-04	180	40	3	85fc9b164147b28545e2397d32302eea03ef6346
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-nan\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCGBP PPP1R3B RASD2	5.58e-04	180	40	3	a0faed4cf23f6d5e6e8f6b0284cea8a5bd0680a0
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADORA3 EEF2K PLEKHG5	5.58e-04	180	40	3	41e8155cc7b3dac9d496e4077845ca6af1591a5c
ToppCell	(2)_5-FU-(4)_COL2.3+_osteoblasts\|(2)_5-FU / Stress and Cell class	TMTC2 COL16A1 LOXL2	5.67e-04	181	40	3	56ae86072858c156681507aecd1bc6cb0a3372d2
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Mesenchymal_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	TMTC2 FBN2 LOXL2	5.67e-04	181	40	3	9b2d207dc9fc2228a1555ed360286bb7c2d988ff
ToppCell	critical-Myeloid-Mast_cell\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	COL16A1 PLPP1 WNK3	5.67e-04	181	40	3	f0d81ae74d3f32979624a94b2ef93774831a7970
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-large_intestine_goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCGBP PLPP1 RASD2	5.67e-04	181	40	3	dae0d106f0eee5dba538617f8ed724925ea35f17
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ADORA3 FCGBP IL1B	5.76e-04	182	40	3	16186b7a0c33caa48631962381e3ab7e5d166163
ToppCell	facs-Skin-Anagen-3m-Epithelial-Basal_IFE\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAM FCGBP COL16A1	5.76e-04	182	40	3	22d6f4790950508e8aa27e02a8133af5f53f13c8
ToppCell	PND01-03-samps-Mesenchymal-Myofibroblast\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	FBN2 COL16A1 LOXL2	5.76e-04	182	40	3	812dac35b9aa05be48258082e007f6c00e7b4dd8
ToppCell	wk_08-11-Mesenchymal-Chondrocyte-Resting_chondrocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	COL16A1 WNK4 SIPA1L1	5.76e-04	182	40	3	00a148b1e499bf16325491536d187d4dd6b70c06
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_ISOC1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAM TMTC2 FBN2	5.85e-04	183	40	3	7961e05c6e9964da159059c6bfb4f7e7e14308c2
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-large_intestine_goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCGBP PLPP1 RASD2	5.85e-04	183	40	3	ee9c88be88221b7ad4ea9f890b17d6156fb3432e
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-Goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCGBP PLPP1 RASD2	5.85e-04	183	40	3	c52b84034503d931f7b87312d2ff86daff14152d
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBN2 PPP1R3B LOXL2	5.95e-04	184	40	3	e93633d89a9c54c8d2819f56372815b4ca149f06
ToppCell	(2)_5-FU-(4)_COL2.3+_osteoblasts\|World / Stress and Cell class	TMTC2 COL16A1 LOXL2	5.95e-04	184	40	3	684d05340a3dfb8aa08b881516a37f9627a10448
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_ISOC1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAM TMTC2 FBN2	6.04e-04	185	40	3	ae53aa2ecfe418a5dbd7d963a995bc06dab94f56
ToppCell	Fetal_29-31_weeks-Mesenchymal-chondrocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FBN2 COL16A1 WNK4	6.04e-04	185	40	3	b8052cebb73f41abe6faf0aa847be7c8ef23ae94
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADORA3 EEF2K PLEKHG5	6.04e-04	185	40	3	5527fa9d2e0b2f3607602e18ba94de4e9bbc6824
ToppCell	P03-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PAM FBN2 COL16A1	6.14e-04	186	40	3	c0a036096c2cb23305605b8aaf18869d6e0fb512
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-chondrocyte\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL16A1 LOXL2 WNK4	6.14e-04	186	40	3	80a0a42ca8585cdb1dda57a18c254316a126ee64
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-large_intestine_goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCGBP PLPP1 RASD2	6.14e-04	186	40	3	32d30f08b20a0a28e38b37bd52ab26d1d43736ce
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	PAM AKT3 LOXL2	6.14e-04	186	40	3	cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_granulocytic\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MAOA IL1B WNK3	6.33e-04	188	40	3	36ff615154d6d9e3ba6ccb73a0f11574bcbf5ece
ToppCell	Mesenchymal-chondrocyte\|World / Lineage, Cell type, age group and donor	FBN2 COL16A1 WNK4	6.33e-04	188	40	3	7b1e3f8a941eaa68e89c562129a92314642eec66
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ADORA3 FCGBP IL1B	6.33e-04	188	40	3	3f47395db7e6159fc95810545bad4b6e028464c5
ToppCell	Monocytes-Tissue-resident_macrophages\|World / Immune cells in Kidney/Urine in Lupus Nephritis	ADORA3 FCGBP IL1B	6.53e-04	190	40	3	07215e8f292cb54c670037aaf28393cddbe5548c
ToppCell	(2)_Dendritic_Cells\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	ADORA3 FCGBP IL1B	6.53e-04	190	40	3	5163a5be95fb6c2609bfa3d69166af172f74e724
ToppCell	ILEUM-non-inflamed-(8)_Activated_fibroblasts\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	COL16A1 LOXL2 EPHA2	6.53e-04	190	40	3	39fa110d19c97c7cac99f5fb91b26bc08e2f3b42
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EEF2K COL16A1 PLPP1	6.63e-04	191	40	3	2c51850f5c559d665b8a27a12b75af9ed58dffe1
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMTC2 FBN2 COL16A1	6.73e-04	192	40	3	f053b89bfd6048c227667ff01c38df7c51d8a496
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAM TMTC2 FBN2	6.73e-04	192	40	3	dc40ef2341e5d6a6d479f140e023fe1bf687928d
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAM TMTC2 FBN2	6.83e-04	193	40	3	c7e9e6e4bf5e07c9cbdf1aa7c8828f4b2500e3ff
ToppCell	Monocytes-Tissue-resident_macrophages\|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis	ADORA3 FCGBP PPP1R3B	6.83e-04	193	40	3	198552810dcac8d0ca63a78badd6702b49ff6edf
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAM COL16A1 LOXL2	6.83e-04	193	40	3	428b1a3ad87dff7f65de5161d40f102572a9341b
ToppCell	3'-Adult-LargeIntestine-Epithelial-goblet\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FCGBP WNK4 RASD2	6.93e-04	194	40	3	1a188e52f2f0b6eca3e8d4a4671d9beab0fbbb88
ToppCell	356C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	ADORA3 FBN2 FCGBP	6.93e-04	194	40	3	11ff53a748160570d2908ea9eb9779c038e5b676
ToppCell	medial-2-Hematologic-EREG+_Dendritic\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADORA3 IL1B LOXL2	6.93e-04	194	40	3	b2b4e4c3ac0df0d9f17b930ffb60c0fd85b3dd78
Drug	benzylhydrazine	PAM MAOA LOXL2	1.80e-06	14	40	3	CID000011157
Drug	paeonol	AKT1 MAOA IL1B	4.77e-06	19	40	3	ctd:C013638
Drug	Clenbuterol	AKT1 AKT3 IL1B	9.91e-06	24	40	3	ctd:D002976
Drug	thallium	MAOA BIRC6 LOXL2	1.12e-05	25	40	3	CID000105005
Drug	sumatriptan	ADCY10 ADORA3 MAOA LOXL2	1.17e-05	80	40	4	CID000005358
Drug	desipramine	ADORA3 MAOA IL1B PLPP1 LOXL2	1.89e-05	188	40	5	CID000002995
Drug	Dicumarol [66-76-2]; Up 200; 11.8uM; MCF7; HT_HG-U133A	ADCY10 PAM ADORA3 IL1B LOXL2	2.43e-05	198	40	5	3941_UP
Drug	beta-tricalcium phosphate	AKT1 IL1B	3.00e-05	5	40	2	ctd:C485817
Drug	DOPEG	EEF2K MAOA LOXL2	3.45e-05	36	40	3	CID000091528
Drug	eye gene	ADCY10 ADORA3 AKT1 MAOA IL1B LOXL2	4.19e-05	369	40	6	CID000004782
Drug	1-benzyl-2-methyl-5-methoxytryptamine	MAOA LOXL2	4.49e-05	6	40	2	CID000009925
Drug	BU99006	MAOA LOXL2	4.49e-05	6	40	2	CID006603748
Drug	5-hydroxyisatin	MAOA LOXL2	4.49e-05	6	40	2	CID010352011
Drug	T 794	MAOA LOXL2	4.49e-05	6	40	2	CID003077680
Drug	quercetagetin	AKT1 IL1B	4.49e-05	6	40	2	ctd:C079163
Drug	NSD 2023	MAOA LOXL2	4.49e-05	6	40	2	CID000019831
Drug	1-PCPA	MAOA LOXL2	4.49e-05	6	40	2	CID000194548
Drug	N-cyclopropyl-5,6-dimethoxytryptamine	MAOA LOXL2	4.49e-05	6	40	2	CID000156277
Drug	N-cyclopropyl-6,7-dimethoxytryptamine	MAOA LOXL2	4.49e-05	6	40	2	CID000156278
Drug	N-cyclopropyl-alpha-methylbenzylamine	MAOA LOXL2	4.49e-05	6	40	2	CID000362778
Drug	Iron	PAM AKT1 EEF2K MAOA IL1B PLPP1	5.08e-05	382	40	6	ctd:D007501
Drug	dimethylphenethylamine	MAOA LOXL2	6.28e-05	7	40	2	CID000025124
Drug	BU 224	MAOA LOXL2	6.28e-05	7	40	2	CID000002457
Drug	M 2113	MAOA LOXL2	6.28e-05	7	40	2	CID000072895
Drug	N-(2-aminoethyl)benzamide	MAOA LOXL2	6.28e-05	7	40	2	CID000423156
Drug	cimoxatone	MAOA LOXL2	6.28e-05	7	40	2	CID000052542
Drug	iproclozide	MAOA LOXL2	6.28e-05	7	40	2	CID000019063
Drug	brofaromine	MAOA LOXL2	6.28e-05	7	40	2	CID000044570
Drug	tetrahydroharmine	MAOA LOXL2	6.28e-05	7	40	2	CID000159809
Drug	4'-amino-MPTP	MAOA LOXL2	6.28e-05	7	40	2	CID000086263
Drug	4-methoxytranylcypromine	MAOA LOXL2	6.28e-05	7	40	2	CID003082143
Drug	1-Phenylcyclobutylamine	MAOA LOXL2	6.28e-05	7	40	2	CID000152214
Drug	JB 835	MAOA LOXL2	6.28e-05	7	40	2	CID000152988
Drug	1-benzylcyclopropylamine	MAOA LOXL2	6.28e-05	7	40	2	CID000152923
Drug	RS-2232	MAOA LOXL2	6.28e-05	7	40	2	CID000134882
Drug	SR 95191	MAOA LOXL2	6.28e-05	7	40	2	CID000072119
Drug	MPTP-3-ol	MAOA LOXL2	6.28e-05	7	40	2	CID000100194
Drug	efaroxan	MAOA LOXL2 RASD2	7.24e-05	46	40	3	CID000072016
Drug	AC1O5VTH	MAOA LOXL2	8.37e-05	8	40	2	CID006441710
Drug	Dithionite	PAM AKT1	8.37e-05	8	40	2	ctd:D004227
Drug	AC1Q6B1A	MAOA LOXL2	8.37e-05	8	40	2	CID000088562
Drug	amezinium	MAOA LOXL2	8.37e-05	8	40	2	CID000071926
Drug	mebanazine	MAOA LOXL2	8.37e-05	8	40	2	CID000006179
Drug	mofegiline	MAOA LOXL2	8.37e-05	8	40	2	CID006437850
Drug	pyrazidol	MAOA LOXL2	8.37e-05	8	40	2	CID000068802
Drug	4-fluorotranylcypromine	MAOA LOXL2	8.37e-05	8	40	2	CID003082666
Drug	ranbezolid	MAOA LOXL2	8.37e-05	8	40	2	CID000496993
Drug	2-propyl-pentylamine	MAOA LOXL2	8.37e-05	8	40	2	CID000170419
Drug	phlorofucofuroeckol A	AKT1 IL1B	8.37e-05	8	40	2	ctd:C064093
Drug	amitriptyline	ADORA3 MAOA IL1B LOXL2	1.05e-04	140	40	4	CID000002160
Drug	Lilly 51641	MAOA LOXL2	1.08e-04	9	40	2	CID000021485
Drug	3-amino-2-oxazolidinone	MAOA LOXL2	1.08e-04	9	40	2	CID000065725
Drug	toloxatone	MAOA LOXL2	1.08e-04	9	40	2	CID000034521
Drug	MDL 72392	MAOA LOXL2	1.08e-04	9	40	2	CID006439254
Drug	AC1L4KA6	MAOA LOXL2	1.08e-04	9	40	2	CID000158620
Drug	AC1L1BMC	MAOA LOXL2	1.08e-04	9	40	2	CID000001500
Drug	FLA 336	MAOA LOXL2	1.08e-04	9	40	2	CID000123706
Drug	Zyflamend	AKT1 IL1B	1.08e-04	9	40	2	ctd:C519312
Drug	RS-8359	MAOA LOXL2	1.08e-04	9	40	2	CID000164116
Drug	pinoline	MAOA LOXL2	1.08e-04	9	40	2	CID000001868
Drug	Ro 16-6491	MAOA LOXL2	1.08e-04	9	40	2	CID000004289
Drug	Harmaline	MAOA IL1B	1.08e-04	9	40	2	ctd:D006246
Drug	FLA 365	MAOA LOXL2	1.08e-04	9	40	2	CID000072776
Drug	J 508	MAOA LOXL2	1.08e-04	9	40	2	CID000155219
Drug	EXP 561	MAOA LOXL2	1.34e-04	10	40	2	CID000027696
Drug	U-0521	MAOA LOXL2	1.34e-04	10	40	2	CID000021632
Drug	acetylcadaverine	MAOA LOXL2	1.34e-04	10	40	2	CID000189087
Drug	Monase	MAOA LOXL2	1.34e-04	10	40	2	CID000008366
Drug	3-dimethylamino-1-propyne	MAOA LOXL2	1.34e-04	10	40	2	CID000081643
Drug	N-cyclopropylbenzylamine	MAOA LOXL2	1.34e-04	10	40	2	CID000025866
Drug	safrazine	MAOA LOXL2	1.34e-04	10	40	2	CID000034041
Drug	NmiQ	MAOA LOXL2	1.34e-04	10	40	2	CID000019850
Drug	NSC-169892	MAOA LOXL2	1.34e-04	10	40	2	CID000043479
Drug	Adenosine	ADCY10 ADORA3 IL1B	1.53e-04	59	40	3	ctd:D000241
Drug	piperine	AKT1 MAOA IL1B	1.53e-04	59	40	3	ctd:C008922
Drug	nortriptyline	MAOA IL1B LOXL2	1.53e-04	59	40	3	CID000004543
Drug	befloxatone	MAOA LOXL2	1.64e-04	11	40	2	CID000060824
Drug	4-hydroxy-3-methoxyphenylglycol-piperazine	MAOA LOXL2	1.64e-04	11	40	2	CID002723890
Drug	Geraniin	AKT1 IL1B	1.64e-04	11	40	2	ctd:C024603
Drug	Amiflamina	MAOA LOXL2	1.64e-04	11	40	2	CID000071221
Drug	meperidine	MAOA IL1B LOXL2	1.85e-04	63	40	3	CID000004058
Drug	FNPA	MAOA LOXL2	1.96e-04	12	40	2	CID000093121
Drug	2-(2-benzofuranyl)-2-imidazoline	MAOA LOXL2	1.96e-04	12	40	2	CID003080926
Drug	HLA20	MAOA LOXL2	1.96e-04	12	40	2	CID006918819
Drug	tylciprine	MAOA LOXL2	1.96e-04	12	40	2	CID000026069
Drug	pheniprazine	MAOA LOXL2	1.96e-04	12	40	2	CID000005929
Drug	viloxazine	MAOA LOXL2	1.96e-04	12	40	2	CID000005666
Drug	MPDP	MAOA LOXL2	1.96e-04	12	40	2	CID000150458
Drug	S-(-)-Lisuride	ADCY10 MAOA LOXL2	2.03e-04	65	40	3	CID000003938
Drug	amiloride	MAOA IL1B LOXL2 WNK4 WNK3	2.17e-04	315	40	5	CID000016230
Drug	diethyl maleate	ADORA3 EEF2K LRTM2 MAOA PPP1R3B	2.27e-04	318	40	5	ctd:C014476
Drug	sulfallate	IL1B KYAT1	2.32e-04	13	40	2	CID000007216
Drug	SKF 64139	MAOA LOXL2	2.32e-04	13	40	2	CID000123919
Drug	fenfluramine	MAOA PLPP1 BIRC6 LOXL2	2.65e-04	178	40	4	CID000003337
Drug	isocarboxazid	MAOA LOXL2	2.70e-04	14	40	2	CID000003759
Drug	kynuramine	MAOA LOXL2	2.70e-04	14	40	2	CID000009692
Drug	FMMT	MAOA LOXL2	2.70e-04	14	40	2	CID006438682
Drug	MDL 72145	MAOA LOXL2	2.70e-04	14	40	2	CID006438383
Drug	lazabemide	MAOA LOXL2	2.70e-04	14	40	2	CID000071307
Drug	2'CH3-MPTP	MAOA LOXL2	2.70e-04	14	40	2	CID000091767
Disease	Malignant Neoplasms	AKT1 IL1B BIRC6 EPHA2	1.79e-05	128	36	4	C0006826
Disease	pseudohypoaldosteronism (implicated_via_orthology)	WNK4 WNK3	2.16e-05	6	36	2	DOID:4479 (implicated_via_orthology)
Disease	Benign Neoplasm	IL1B BIRC6 EPHA2	7.91e-05	68	36	3	C0086692
Disease	Neoplasms	IL1B BIRC6 EPHA2	7.91e-05	68	36	3	C0027651
Disease	esophageal cancer (is_marker_for)	AKT1 IL1B	9.48e-05	12	36	2	DOID:5041 (is_marker_for)
Disease	prostate adenocarcinoma (is_implicated_in)	AKT1 AKT3	2.71e-04	20	36	2	DOID:2526 (is_implicated_in)
Disease	malignant astrocytoma (is_marker_for)	AKT1 AKT3	3.60e-04	23	36	2	DOID:3069 (is_marker_for)
Disease	Myopathy	MAOA IL1B	6.16e-04	30	36	2	C0026848
Disease	Marijuana Abuse	AKT1 IL1B	6.16e-04	30	36	2	C0024809
Disease	Squamous cell carcinoma of lung	EPHA2 WNK3	7.01e-04	32	36	2	C0149782
Disease	colon cancer (is_implicated_in)	AKT1 AKT3	8.88e-04	36	36	2	DOID:219 (is_implicated_in)
Disease	Parkinson's disease (implicated_via_orthology)	AKT1 AKT3 IL1B	9.28e-04	157	36	3	DOID:14330 (implicated_via_orthology)
Disease	Secondary Biliary Cholangitis	CLEC16A LOXL2	1.21e-03	42	36	2	C0238065
Disease	Biliary cirrhosis	CLEC16A LOXL2	1.21e-03	42	36	2	C0023892
Disease	Biliary Cirrhosis, Primary, 1	CLEC16A LOXL2	1.21e-03	42	36	2	C4551595
Disease	pulmonary tuberculosis (is_implicated_in)	AKT1 IL1B	1.21e-03	42	36	2	DOID:2957 (is_implicated_in)
Disease	Multiple Sclerosis	IL1B CLEC16A	1.39e-03	45	36	2	C0026769
Disease	Multiple Sclerosis, Acute Fulminating	IL1B CLEC16A	1.39e-03	45	36	2	C0751324
Disease	Primary biliary cirrhosis	CLEC16A LOXL2	1.51e-03	47	36	2	C0008312
Disease	Fibrosis	AKT1 IL1B	1.71e-03	50	36	2	C0016059
Disease	Cirrhosis	AKT1 IL1B	1.71e-03	50	36	2	C1623038
Disease	alcohol use disorder (implicated_via_orthology)	AKT1 AKT3 PPP1R3B	1.73e-03	195	36	3	DOID:1574 (implicated_via_orthology)
Disease	Hypotension	MAOA IL1B	1.92e-03	53	36	2	C0020649

Protein segments in the cluster

Peptide	Gene	Start	Entry
GVVMYEMMCGRLPFY	AKT1	336	P31749
TAMCFENMRIMRYEE	AADACL2	46	Q6P093
HMMLQPILTYMACGY	BIRC6	3051	Q9NR09
CQFVSVMRMDYMVYF	ADORA3	166	P0DMS8
AYYTSRMQFPMEMAA	COL16A1	1456	Q07092
SDEMCNLYIMYYMEA	PAM	306	P19021
RMMMYYPGIVTCDSV	ADCY10	416	Q96PN6
MYEMMCGRLPFYNQD	AKT3	336	Q9Y243
QRLPMGAVIKCMMYY	MAOA	296	P21397
YQSMNCKPMQMYVLD	FBXO42	636	Q6P3S6
ECHMLAAMAYDRYMA	OR8G1	111	Q15617
MAEVPELASEMMAYY	IL1B	1	P01584
YPVAMNRRMCAEMAG	OR10S1	146	Q8NGN2
LMEMVMTNNYSYPPC	INTS1	766	Q8N201
TYLEDRPMFMLQCAM	LOXL2	561	Q9Y4K0
HYPTVMNPRTCYAMM	OR4N2	131	Q8NGD1
EVMMLAVMAYDRYVA	OR8J3	111	Q8NGG0
DRYVAICNPLMYMVV	OR8U9	121	P0C7N5
ECLILVMMSYDRYMA	OR2A5	111	Q96R48
VMMSYDRYMAICHPL	OR2A5	116	Q96R48
DCYLLAMMAVDPYVA	OR5AK2	111	Q8NH90
RRYDMMGTCSYTMVE	FCGBP	486	Q9Y6R7
QNIMNDMPIYMYSVC	EPHA2	56	P29317
DMPIYMYSVCNVMSG	EPHA2	61	P29317
YDGMQDEPRYMMLAR	EEF2K	656	O00418
MMVIPQAYHLCYVLM	DCST2	221	Q5T1A1
YRCLCYDGFMASMDM	FBN2	1306	P35556
MMAVDIEYRYNCMAP	PPP1R3B	1	Q86XI6
PMESCTFMVMAYDRY	OR56A1	116	Q8NGH5
VAMAYDRYVAICFPM	OR1E2	116	P47887
ECVLLPMMAYDRYVA	OR13F1	111	Q8NGS4
MVPMEMFNYCSQLED	LRTM2	241	Q8N967
IEPFFDCYEPMTMMA	KYAT1	121	Q16773
MYCMLFVALYLQARM	PLPP1	176	O14494
SCSETYRMPVMEYKM	SIPA1L1	1036	O43166
DEYRSMTMKPMNVEY	CLEC16A	616	Q2KHT3
LVMEMYELCMFFRNY	SPG11	1551	Q96JI7
IRYCMEEEGCMEYMR	PLEKHG5	436	O94827
APQSLYNMMGEAYMR	TMTC2	641	Q8N394
PFCMRRVKEMDAYGM	RASD2	216	Q96D21
YNVLCTMYTDIMDPM	UBQLN3	251	Q9H347
FGMCMLEMATSEYPY	WNK4	361	Q96J92
MCMLEMATSEYPYSE	WNK3	336	Q9BYP7