| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | ubiquitin protein ligase activity | 1.50e-04 | 372 | 62 | 7 | GO:0061630 | |
| GeneOntologyMolecularFunction | nucleoside-triphosphatase regulator activity | 1.66e-04 | 507 | 62 | 8 | GO:0060589 | |
| GeneOntologyMolecularFunction | GTPase regulator activity | 1.66e-04 | 507 | 62 | 8 | GO:0030695 | |
| GeneOntologyMolecularFunction | ubiquitin-like protein ligase activity | 2.27e-04 | 398 | 62 | 7 | GO:0061659 | |
| GeneOntologyMolecularFunction | ubiquitin-protein transferase activity | 6.39e-04 | 473 | 62 | 7 | GO:0004842 | |
| GeneOntologyMolecularFunction | guanyl-nucleotide exchange factor activity | 7.51e-04 | 231 | 62 | 5 | GO:0005085 | |
| GeneOntologyMolecularFunction | ubiquitin-like protein transferase activity | 1.02e-03 | 512 | 62 | 7 | GO:0019787 | |
| GeneOntologyMolecularFunction | enzyme regulator activity | TBC1D13 GAPVD1 GBF1 NF1 ARHGEF38 ARFGEF2 CCNO RICTOR RIC8A WFDC8 ARHGAP35 SEC14L2 | 1.22e-03 | 1418 | 62 | 12 | GO:0030234 |
| GeneOntologyMolecularFunction | aminoacyltransferase activity | 1.27e-03 | 532 | 62 | 7 | GO:0016755 | |
| GeneOntologyMolecularFunction | GTPase activating protein binding | 1.57e-03 | 19 | 62 | 2 | GO:0032794 | |
| GeneOntologyMolecularFunction | GTPase activator activity | 1.74e-03 | 279 | 62 | 5 | GO:0005096 | |
| GeneOntologyMolecularFunction | acyltransferase activity | 2.63e-03 | 775 | 62 | 8 | GO:0016746 | |
| Domain | ARM-type_fold | GBF1 NF1 INF2 INSC ARFGEF2 RICTOR RIC8A ATM STKLD1 HEATR5B STAG2 | 1.33e-08 | 339 | 62 | 11 | IPR016024 |
| Domain | ARM-like | 2.96e-06 | 270 | 62 | 8 | IPR011989 | |
| Domain | Sec7_N | 6.48e-05 | 4 | 62 | 2 | IPR032691 | |
| Domain | Sec7_N | 6.48e-05 | 4 | 62 | 2 | PF12783 | |
| Domain | - | 9.30e-05 | 222 | 62 | 6 | 1.25.10.10 | |
| Domain | ZF_RING_1 | 4.02e-04 | 291 | 62 | 6 | PS00518 | |
| Domain | ZF_RING_2 | 4.56e-04 | 298 | 62 | 6 | PS50089 | |
| Domain | RING | 5.15e-04 | 305 | 62 | 6 | SM00184 | |
| Domain | Znf_RING | 7.30e-04 | 326 | 62 | 6 | IPR001841 | |
| Domain | RasGAP | 1.11e-03 | 15 | 62 | 2 | PF00616 | |
| Domain | RAS_GTPASE_ACTIV_1 | 1.11e-03 | 15 | 62 | 2 | PS00509 | |
| Domain | - | 1.11e-03 | 15 | 62 | 2 | 1.10.1000.11 | |
| Domain | RAS_GTPASE_ACTIV_2 | 1.11e-03 | 15 | 62 | 2 | PS50018 | |
| Domain | Sec7 | 1.11e-03 | 15 | 62 | 2 | PF01369 | |
| Domain | Sec7_alpha_orthog | 1.11e-03 | 15 | 62 | 2 | IPR023394 | |
| Domain | Sec7 | 1.26e-03 | 16 | 62 | 2 | SM00222 | |
| Domain | SEC7 | 1.26e-03 | 16 | 62 | 2 | PS50190 | |
| Domain | Sec7_dom | 1.26e-03 | 16 | 62 | 2 | IPR000904 | |
| Domain | RasGAP_dom | 1.60e-03 | 18 | 62 | 2 | IPR001936 | |
| Domain | SEC14 | 3.10e-03 | 25 | 62 | 2 | SM00516 | |
| Domain | Rho_GTPase_activation_prot | 3.13e-03 | 88 | 62 | 3 | IPR008936 | |
| Domain | CRAL_TRIO | 3.61e-03 | 27 | 62 | 2 | PS50191 | |
| Domain | - | 3.68e-03 | 449 | 62 | 6 | 3.30.40.10 | |
| Domain | CRAL-TRIO_dom | 3.88e-03 | 28 | 62 | 2 | IPR001251 | |
| Domain | Znf_RING/FYVE/PHD | 4.10e-03 | 459 | 62 | 6 | IPR013083 | |
| Domain | ATPase_AAA_CS | 4.16e-03 | 29 | 62 | 2 | IPR003960 | |
| Domain | AAA | 5.68e-03 | 34 | 62 | 2 | PS00674 | |
| Pubmed | CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI. | 3.66e-08 | 104 | 63 | 6 | 31240132 | |
| Pubmed | NF1 patient missense variants predict a role for ATM in modifying neurofibroma initiation. | 3.23e-06 | 2 | 63 | 2 | 31664505 | |
| Pubmed | 3.23e-06 | 2 | 63 | 2 | 31332286 | ||
| Pubmed | STAG2 Regulates Homologous Recombination Repair and Sensitivity to ATM Inhibition. | 3.23e-06 | 2 | 63 | 2 | 37985839 | |
| Pubmed | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | GBF1 SYNE3 RARG INF2 LONRF1 FANCI ARFGEF2 BAMBI RIC8A UBE3C ARHGAP35 | 4.30e-06 | 1105 | 63 | 11 | 35748872 |
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 18003980 | ||
| Pubmed | 9.68e-06 | 3 | 63 | 2 | 23386609 | ||
| Pubmed | Large-scale characterization of HeLa cell nuclear phosphoproteins. | 1.03e-05 | 774 | 63 | 9 | 15302935 | |
| Pubmed | 1.40e-05 | 288 | 63 | 6 | 23383273 | ||
| Pubmed | FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway. | 1.93e-05 | 4 | 63 | 2 | 18931676 | |
| Pubmed | Interaction between the triglyceride lipase ATGL and the Arf1 activator GBF1. | 3.22e-05 | 5 | 63 | 2 | 21789191 | |
| Pubmed | Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin. | 3.22e-05 | 5 | 63 | 2 | 15199141 | |
| Pubmed | PSMC3 promotes RNAi by maintaining AGO2 stability through USP14. | 4.82e-05 | 6 | 63 | 2 | 36528617 | |
| Pubmed | 6.86e-05 | 120 | 63 | 4 | 27320910 | ||
| Pubmed | 8.98e-05 | 8 | 63 | 2 | 11929878 | ||
| Pubmed | The binary interacting network of the conserved oligomeric Golgi tethering complex. | 8.98e-05 | 8 | 63 | 2 | 15047703 | |
| Pubmed | DNA polymerase POLN participates in cross-link repair and homologous recombination. | 8.98e-05 | 8 | 63 | 2 | 19995904 | |
| Pubmed | 8.98e-05 | 8 | 63 | 2 | 11980916 | ||
| Pubmed | 8.98e-05 | 8 | 63 | 2 | 27066481 | ||
| Pubmed | 1.12e-04 | 606 | 63 | 7 | 36538041 | ||
| Pubmed | 1.15e-04 | 9 | 63 | 2 | 27340174 | ||
| Pubmed | Deregulated E2f-2 underlies cell cycle and maturation defects in retinoblastoma null erythroblasts. | 1.15e-04 | 9 | 63 | 2 | 17923680 | |
| Pubmed | The laforin/malin E3-ubiquitin ligase complex ubiquitinates pyruvate kinase M1/M2. | 1.44e-04 | 10 | 63 | 2 | 26493215 | |
| Pubmed | 1.44e-04 | 10 | 63 | 2 | 17478428 | ||
| Pubmed | 1.54e-04 | 638 | 63 | 7 | 33239621 | ||
| Pubmed | Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. | 1.58e-04 | 149 | 63 | 4 | 19549727 | |
| Pubmed | Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly. | 1.76e-04 | 11 | 63 | 2 | 20427287 | |
| Pubmed | 1.76e-04 | 11 | 63 | 2 | 28396413 | ||
| Pubmed | 1.76e-04 | 11 | 63 | 2 | 24800743 | ||
| Pubmed | 1.77e-04 | 653 | 63 | 7 | 22586326 | ||
| Pubmed | HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis. | 2.11e-04 | 12 | 63 | 2 | 24005329 | |
| Pubmed | 2.11e-04 | 12 | 63 | 2 | 38367882 | ||
| Pubmed | 2.18e-04 | 64 | 63 | 3 | 20332099 | ||
| Pubmed | 2.29e-04 | 304 | 63 | 5 | 32235678 | ||
| Pubmed | 2.44e-04 | 1168 | 63 | 9 | 19946888 | ||
| Pubmed | 2.46e-04 | 689 | 63 | 7 | 36543142 | ||
| Pubmed | Comparative interactome analysis of α-arrestin families in human and Drosophila. | 2.62e-04 | 313 | 63 | 5 | 38270169 | |
| Pubmed | LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling. | 2.92e-04 | 942 | 63 | 8 | 31073040 | |
| Pubmed | 3.34e-04 | 15 | 63 | 2 | 19536649 | ||
| Pubmed | Cdk12 Regulates Neurogenesis and Late-Arising Neuronal Migration in the Developing Cerebral Cortex. | 3.34e-04 | 15 | 63 | 2 | 27073218 | |
| Pubmed | 3.81e-04 | 16 | 63 | 2 | 20010835 | ||
| Pubmed | 5.03e-04 | 85 | 63 | 3 | 19028597 | ||
| Pubmed | 5.16e-04 | 363 | 63 | 5 | 25036637 | ||
| Pubmed | Autoregulation of the 26S proteasome by in situ ubiquitination. | 5.41e-04 | 19 | 63 | 2 | 24743594 | |
| Pubmed | A crucial role for Arf6 in the response of commissural axons to Slit. | 5.41e-04 | 19 | 63 | 2 | 30674481 | |
| Pubmed | Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes. | 5.41e-04 | 19 | 63 | 2 | 20801936 | |
| Pubmed | 6.01e-04 | 20 | 63 | 2 | 12702649 | ||
| Pubmed | Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV. | 6.40e-04 | 1061 | 63 | 8 | 33845483 | |
| Pubmed | Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice. | 6.48e-04 | 582 | 63 | 6 | 20467437 | |
| Pubmed | 7.29e-04 | 22 | 63 | 2 | 18460603 | ||
| Pubmed | 7.53e-04 | 225 | 63 | 4 | 25277244 | ||
| Pubmed | Gene network analysis in a pediatric cohort identifies novel lung function genes. | 8.69e-04 | 24 | 63 | 2 | 24023788 | |
| Pubmed | 9.31e-04 | 105 | 63 | 3 | 22493164 | ||
| Pubmed | 9.57e-04 | 106 | 63 | 3 | 18654987 | ||
| Pubmed | 1.03e-03 | 878 | 63 | 7 | 37223481 | ||
| Pubmed | 1.10e-03 | 1440 | 63 | 9 | 30833792 | ||
| Pubmed | 5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia. | 1.10e-03 | 27 | 63 | 2 | 23027611 | |
| Pubmed | 1.29e-03 | 446 | 63 | 5 | 24255178 | ||
| Pubmed | 1.45e-03 | 31 | 63 | 2 | 26678539 | ||
| Pubmed | Identification of host proteins required for HIV infection through a functional genomic screen. | 1.52e-03 | 272 | 63 | 4 | 18187620 | |
| Pubmed | 1.75e-03 | 34 | 63 | 2 | 12549820 | ||
| Pubmed | Mouse screen reveals multiple new genes underlying mouse and human hearing loss. | 1.75e-03 | 1242 | 63 | 8 | 30973865 | |
| Interaction | FAM234A interactions | 9.26e-08 | 126 | 60 | 7 | int:FAM234A | |
| Interaction | FPR1 interactions | 2.66e-07 | 147 | 60 | 7 | int:FPR1 | |
| Interaction | EFNA4 interactions | 5.23e-07 | 239 | 60 | 8 | int:EFNA4 | |
| Interaction | GPR182 interactions | 8.56e-07 | 455 | 60 | 10 | int:GPR182 | |
| Interaction | NPTN interactions | 1.63e-06 | 278 | 60 | 8 | int:NPTN | |
| Interaction | GPR17 interactions | 1.86e-06 | 283 | 60 | 8 | int:GPR17 | |
| Interaction | ARRDC4 interactions | 4.80e-06 | 83 | 60 | 5 | int:ARRDC4 | |
| Interaction | CD40 interactions | 6.20e-06 | 153 | 60 | 6 | int:CD40 | |
| Interaction | SIGLECL1 interactions | 2.17e-05 | 113 | 60 | 5 | int:SIGLECL1 | |
| Interaction | GYPB interactions | 2.32e-05 | 56 | 60 | 4 | int:GYPB | |
| Interaction | C3orf18 interactions | 2.36e-05 | 115 | 60 | 5 | int:C3orf18 | |
| Interaction | UNC93B1 interactions | 3.14e-05 | 417 | 60 | 8 | int:UNC93B1 | |
| Interaction | OCIAD1 interactions | 3.24e-05 | 419 | 60 | 8 | int:OCIAD1 | |
| Interaction | HCST interactions | 3.26e-05 | 205 | 60 | 6 | int:HCST | |
| Interaction | CTDP1 interactions | 3.45e-05 | 207 | 60 | 6 | int:CTDP1 | |
| Interaction | OPALIN interactions | 3.64e-05 | 209 | 60 | 6 | int:OPALIN | |
| Interaction | OPRM1 interactions | 6.92e-05 | 144 | 60 | 5 | int:OPRM1 | |
| Interaction | GZMH interactions | 6.99e-05 | 74 | 60 | 4 | int:GZMH | |
| Interaction | TRIM65 interactions | 9.48e-05 | 80 | 60 | 4 | int:TRIM65 | |
| Interaction | VSIG2 interactions | 1.17e-04 | 32 | 60 | 3 | int:VSIG2 | |
| Interaction | SLC2A9 interactions | 1.28e-04 | 33 | 60 | 3 | int:SLC2A9 | |
| Interaction | STKLD1 interactions | 1.30e-04 | 6 | 60 | 2 | int:STKLD1 | |
| Interaction | CD70 interactions | 1.35e-04 | 166 | 60 | 5 | int:CD70 | |
| Interaction | SCN2B interactions | 1.85e-04 | 95 | 60 | 4 | int:SCN2B | |
| Interaction | P2RY8 interactions | 1.92e-04 | 179 | 60 | 5 | int:P2RY8 | |
| Interaction | VSIG4 interactions | 1.97e-04 | 180 | 60 | 5 | int:VSIG4 | |
| Interaction | F2RL1 interactions | 2.08e-04 | 182 | 60 | 5 | int:F2RL1 | |
| Interaction | GPR45 interactions | 2.64e-04 | 300 | 60 | 6 | int:GPR45 | |
| Interaction | COMTD1 interactions | 3.21e-04 | 200 | 60 | 5 | int:COMTD1 | |
| Interaction | GCGR interactions | 3.24e-04 | 110 | 60 | 4 | int:GCGR | |
| Interaction | HIF1A interactions | 3.25e-04 | 441 | 60 | 7 | int:HIF1A | |
| Cytoband | 1q44 | 4.79e-04 | 110 | 63 | 3 | 1q44 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr1q44 | 7.44e-04 | 128 | 63 | 3 | chr1q44 | |
| Cytoband | 4q24 | 1.01e-03 | 34 | 63 | 2 | 4q24 | |
| Cytoband | 15q26.1 | 2.53e-03 | 54 | 63 | 2 | 15q26.1 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr4q24 | 3.02e-03 | 59 | 63 | 2 | chr4q24 | |
| GeneFamily | Components of oligomeric golgi complex | 1.19e-04 | 8 | 38 | 2 | 493 | |
| GeneFamily | Olfactory receptors, family 2 | 1.71e-03 | 113 | 38 | 3 | 149 | |
| GeneFamily | Ring finger proteins | 2.57e-03 | 275 | 38 | 4 | 58 | |
| GeneFamily | AAA ATPases | 5.54e-03 | 53 | 38 | 2 | 413 | |
| ToppCell | Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32 | 8.89e-06 | 92 | 63 | 4 | 926e02725a03d8473eda25d4aef63e34a6566224 | |
| ToppCell | Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32 | 8.89e-06 | 92 | 63 | 4 | d2c1d25e5bb6ba4f406e916e3c0a5ad05492e59d | |
| Drug | N-nitrosopyrrolidine | 4.51e-06 | 40 | 63 | 4 | CID000013591 | |
| Disease | Malignant neoplasm of breast | 8.67e-05 | 1074 | 63 | 10 | C0006142 | |
| Disease | female breast cancer (is_implicated_in) | 1.25e-04 | 8 | 63 | 2 | DOID:0050671 (is_implicated_in) | |
| Disease | leukemia | 2.25e-04 | 55 | 63 | 3 | C0023418 | |
| Disease | Neoplasm of uncertain or unknown behavior of bladder | 4.63e-04 | 15 | 63 | 2 | C0496930 | |
| Disease | Benign neoplasm of bladder | 4.63e-04 | 15 | 63 | 2 | C0154017 | |
| Disease | Carcinoma in situ of bladder | 4.63e-04 | 15 | 63 | 2 | C0154091 | |
| Disease | Carcinoma of bladder | 6.71e-04 | 18 | 63 | 2 | C0699885 | |
| Disease | Glioma | 8.65e-04 | 87 | 63 | 3 | C0017638 | |
| Disease | lung small cell carcinoma (is_implicated_in) | 1.64e-03 | 28 | 63 | 2 | DOID:5409 (is_implicated_in) | |
| Disease | Glioblastoma Multiforme | 1.75e-03 | 111 | 63 | 3 | C1621958 | |
| Disease | NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE | 1.88e-03 | 30 | 63 | 2 | C1868672 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| ALLNMVFCLLAADTC | 811 | Q8IZF5 | |
| SLLAICCLALADRML | 281 | P22674 | |
| EECEALCTRLAIMVK | 2131 | P78363 | |
| IDCLCAMINLATTEL | 471 | Q9H9E3 | |
| CLCSFITLLRDLMLV | 491 | Q9NXL2 | |
| RCAIRIACIFGMQLE | 926 | Q9Y6D5 | |
| SCCLLLLAAVLMVES | 11 | Q9UBU2 | |
| ALETARALMCVAVAL | 76 | P56750 | |
| LSAICLICGDRMDLE | 331 | P13631 | |
| ALCREAAMCAVNRVL | 476 | O15381 | |
| ETFCLEIMDSLRRCL | 581 | Q9NVI1 | |
| DVELKRVMACSRCIL | 261 | Q5VT66 | |
| LADCVLTLLAMECAC | 156 | O95050 | |
| LIDVSDFECSLCMRL | 471 | Q17RB8 | |
| EVRAMCTDLLLACFI | 301 | Q14C86 | |
| LATEVCSREMLNLLC | 241 | P07098 | |
| ECLLLAVMAYDRCVA | 111 | Q7Z3T1 | |
| LIFVCLMVDADRCSL | 226 | Q9HCR9 | |
| LLVALAAVLGCCMEE | 96 | Q86WI0 | |
| ECVLLAVMALDRAAA | 111 | Q8NGU4 | |
| DRMVRACIAIICELA | 181 | Q6R327 | |
| LRIECMLLCEGAAAV | 716 | Q27J81 | |
| ELLCLICKDIMTDAV | 256 | Q7Z6E9 | |
| LGCTECIVLAAMALD | 111 | Q5JQS5 | |
| EALVCNLDCLLDIMT | 121 | Q8N0W3 | |
| MTVKIVCRCLADLRD | 771 | Q8N0W3 | |
| MSLVLNDLLICCRQL | 1 | Q13315 | |
| MAVRCAVAKCLLELQ | 191 | Q9P2D3 | |
| AKICLENCAEIMRLL | 126 | Q96M94 | |
| VLFMARLCQSLGELC | 611 | Q8WTW3 | |
| LCAMAVLLTKGEIRC | 16 | Q13145 | |
| DLLEELLCCLMQLIT | 146 | Q7RTS9 | |
| CECQLLLKEMLERLN | 131 | Q12934 | |
| DMDICRRIDITAKLC | 291 | Q5TF58 | |
| EAVRLSCMSRLIELC | 506 | Q1MX18 | |
| EDAAFCLEMLLRIVL | 1151 | Q92538 | |
| ALCLRALLCEDMFRL | 291 | O00519 | |
| TLVAEILMLQELLCC | 366 | Q8TDG4 | |
| LRTKMRECELLLQEC | 121 | O76054 | |
| RLIGKQCMCLVDLDR | 586 | Q8NEC7 | |
| MREAEISLLECKVCF | 16 | Q6VVB1 | |
| LCLESLDTVMLCREK | 196 | Q96EK7 | |
| LDTVMLCREKLCESL | 201 | Q96EK7 | |
| ECLLLAVMCFDRFVA | 111 | Q9GZK3 | |
| CFLCVLAAVDIVMAS | 91 | Q8NH67 | |
| VDLVLRMAEALLACC | 61 | Q6ZMZ3 | |
| LLLCCLDLIFANAIM | 201 | P28749 | |
| RQACDICAIAMSLVA | 131 | Q9BY78 | |
| DLADVDLRIVMCLMC | 776 | Q9NRY4 | |
| MDVVLESLKCLCNLV | 111 | Q9NPQ8 | |
| LDCAMDACINLGLLE | 331 | Q9H7B4 | |
| DSLDMIERCICLVCL | 376 | P28329 | |
| LNEDACRTACMLIVK | 136 | Q8IUA0 | |
| RICMDAVIDCVLLEC | 326 | Q969K3 | |
| MELHDRVLDVQLCAC | 376 | Q8NE28 | |
| LIEIMLCTIRQAAEC | 521 | Q8N3U4 | |
| ALERLKVMCEEALCS | 281 | Q6IQ16 | |
| CKAVCVEAGMIALRR | 396 | P17980 | |
| CRLIELTVLDKCRLM | 806 | Q6P2S7 | |
| ADVDLMIDCLVSCFR | 371 | P21359 | |
| LLLVCCAMLMLIREQ | 351 | Q9NVG8 | |
| VCLMDVAKREIICAF | 546 | Q6P2C0 | |
| CKNMVLAERCVLLSA | 496 | Q9Y2L5 | |
| MAAQLLEEKLTCAIC | 1 | Q6PJ69 | |
| ELIMLSRCLRDACLG | 541 | Q15386 | |
| LAIDICMSKRLGVCA | 86 | Q8NBV4 |