Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionalpha-ketoglutarate transmembrane transporter activity

SLC13A2 SLC22A7

2.25e-056252GO:0015139
GeneOntologyMolecularFunctionsphingosine N-acyltransferase activity

CERS6 CERS4

3.15e-057252GO:0050291
GeneOntologyMolecularFunctionlipid transporter activity

XKR8 XKR9 SLC22A7 C2CD2L

9.69e-05196254GO:0005319
GeneOntologyMolecularFunctionphospholipid transporter activity

XKR8 XKR9 C2CD2L

1.06e-0474253GO:0005548
GeneOntologyMolecularFunctiontransporter activity

XKR8 CACNA2D1 SLC13A1 XKR9 SLC13A2 SLC22A7 SLC5A3 C2CD2L

1.18e-041289258GO:0005215
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC13A1 SLC13A2 SLC5A3

1.39e-0481253GO:0015370
GeneOntologyMolecularFunctionphospholipid scramblase activity

XKR8 XKR9

3.75e-0423252GO:0017128
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC13A1 SLC13A2 SLC5A3

4.31e-04119253GO:0015294
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC13A1 SLC13A2 SLC22A7 SLC5A3

4.68e-04296254GO:0015291
GeneOntologyMolecularFunctiondicarboxylic acid transmembrane transporter activity

SLC13A2 SLC22A7

6.84e-0431252GO:0005310
GeneOntologyMolecularFunctionsymporter activity

SLC13A1 SLC13A2 SLC5A3

8.46e-04150253GO:0015293
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC13A1 SLC13A2 SLC5A3

1.24e-03171253GO:0015081
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

XKR8 XKR9

1.85e-0351252GO:0140303
GeneOntologyMolecularFunctionacyltransferase activity

RNF121 CERS6 RNF175 CERS4 AWAT1

2.42e-03775255GO:0016746
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA2D1 SLC13A1 SLC13A2 SLC5A3

2.49e-03465254GO:0046873
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC13A1 SLC13A2 SLC22A7 SLC5A3

2.73e-03477254GO:0022804
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

CERS6 CERS4 AWAT1

3.17e-03238253GO:0016747
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC13A1 SLC13A2 SLC5A3

6.10e-03301253GO:0022853
GeneOntologyMolecularFunctionN-acyltransferase activity

CERS6 CERS4

7.18e-03102252GO:0016410
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

CACNA2D1 SLC13A1 SLC13A2 SLC5A3

7.21e-03627254GO:0022890
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CACNA2D1 SLC13A1 SLC13A2 SLC5A3

8.79e-03664254GO:0008324
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

CACNA2D1 SLC13A1 SLC13A2 SLC5A3

1.38e-02758254GO:0015318
GeneOntologyMolecularFunctiontransmembrane transporter activity

CACNA2D1 SLC13A1 SLC13A2 SLC22A7 SLC5A3

1.41e-021180255GO:0022857
GeneOntologyBiologicalProcessalpha-ketoglutarate transport

SLC13A2 SLC22A7

2.95e-057252GO:0015742
GeneOntologyBiologicalProcessphosphatidylserine exposure on apoptotic cell surface

XKR8 XKR9

9.24e-0512252GO:0070782
GeneOntologyBiologicalProcessengulfment of apoptotic cell

XKR8 XKR9

1.47e-0415252GO:0043652
GeneOntologyCellularComponentapical part of cell

DUOX2 CASR PTCH1 SLC13A1 SLC13A2 SLC22A7 SLC5A3 C2CD2L

3.93e-07592268GO:0045177
GeneOntologyCellularComponentapical plasma membrane

DUOX2 CASR SLC13A1 SLC13A2 SLC22A7 SLC5A3 C2CD2L

1.60e-06487267GO:0016324
DomainNA_SULFATE

SLC13A1 SLC13A2

5.16e-063252PS01271
DomainNa/sul_symport_CS

SLC13A1 SLC13A2

5.16e-063252IPR031312
DomainNa/sul_symport

SLC13A1 SLC13A2

1.72e-055252IPR001898
DomainNa_sulph_symp

SLC13A1 SLC13A2

1.72e-055252PF00939
DomainLag1/Lac1

CERS6 CERS4

2.57e-056252IPR016439
DomainXK-related

XKR8 XKR9

9.39e-0511252PF09815
DomainXK_rel

XKR8 XKR9

9.39e-0511252IPR018629
DomainTLC

CERS6 CERS4

2.04e-0416252PS50922
DomainTLC-dom

CERS6 CERS4

2.04e-0416252IPR006634
DomainTLC

CERS6 CERS4

2.04e-0416252SM00724
DomainTRAM_LAG1_CLN8

CERS6 CERS4

2.04e-0416252PF03798
Domain-

C1QTNF3 TNFSF14

2.03e-03502522.60.120.40
DomainTumour_necrosis_fac-like_dom

C1QTNF3 TNFSF14

2.72e-0358252IPR008983
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC13A1 SLC13A2 SLC22A7 SLC5A3

2.25e-0676184MM15072
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC13A1 SLC13A2 SLC22A7 SLC5A3

3.37e-0684184M27334
PathwayREACTOME_SODIUM_COUPLED_SULPHATE_DI_AND_TRI_CARBOXYLATE_TRANSPORTERS

SLC13A1 SLC13A2

1.54e-055182MM15099
PathwayREACTOME_SODIUM_COUPLED_SULPHATE_DI_AND_TRI_CARBOXYLATE_TRANSPORTERS

SLC13A1 SLC13A2

1.54e-055182M27354
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC13A1 SLC13A2 SLC22A7 SLC5A3

2.01e-04238184MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC13A1 SLC13A2 SLC22A7 SLC5A3

2.39e-04249184M5988
PathwayWP_SYNTHESIS_OF_CERAMIDES_AND_1DEOXYCERAMIDES

CERS6 CERS4

3.50e-0422182M45544
PathwayWP_SPHINGOLIPID_METABOLISM_OVERVIEW

CERS6 CERS4

4.54e-0425182MM15931
PathwayWP_SPHINGOLIPID_METABOLISM_INTEGRATED_PATHWAY

CERS6 CERS4

4.91e-0426182MM15892
PathwayWP_SPHINGOLIPID_METABOLISM_INTEGRATED_PATHWAY

CERS6 CERS4

4.91e-0426182M39784
PathwayWP_SPHINGOLIPID_METABOLISM_OVERVIEW

CERS6 CERS4

5.30e-0427182M39863
PathwayREACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS

CERS6 CERS4

5.30e-0427182MM14646
PathwayWP_SPHINGOLIPID_PATHWAY

CERS6 CERS4

6.56e-0430182M39501
PathwayREACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS

CERS6 CERS4

9.99e-0437182M554
PathwayREACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

CASR TAS2R50

9.99e-0437182MM15067
PathwayREACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

CASR TAS2R50

1.11e-0339182M793
Pubmed

Ceramide synthesis regulates T cell activity and GVHD development.

CERS6 CERS4

5.37e-07226228515365
Pubmed

Cryo-EM structures of the human NaS1 and NaDC1 transporters revealed the elevator transport and allosteric regulation mechanism.

SLC13A1 SLC13A2

5.37e-07226238552027
Pubmed

Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors.

CERS6 CERS4

3.22e-06426212912983
Pubmed

The equilibrium between long and very long chain ceramides is important for the fate of the cell and can be influenced by co-expression of CerS.

CERS6 CERS4

3.22e-06426223538298
Pubmed

Do longevity assurance genes containing Hox domains regulate cell development via ceramide synthesis?

CERS6 CERS4

3.22e-06426212297269
Pubmed

Mammalian Lass6 and its related family members regulate synthesis of specific ceramides.

CERS6 CERS4

5.37e-06526215823095
Pubmed

Enzyme Activities of the Ceramide Synthases CERS2-6 Are Regulated by Phosphorylation in the C-terminal Region.

CERS6 CERS4

5.37e-06526226887952
Pubmed

Molecular properties of the SLC13 family of dicarboxylate and sulfate transporters.

SLC13A1 SLC13A2

5.37e-06526216211368
Pubmed

Kinetic characterization of mammalian ceramide synthases: determination of K(m) values towards sphinganine.

CERS6 CERS4

8.05e-06626217977534
Pubmed

Oxidized phospholipids induce ceramide accumulation in RAW 264.7 macrophages: role of ceramide synthases.

CERS6 CERS4

8.05e-06626223936132
Pubmed

Exposure of phosphatidylserine by Xk-related protein family members during apoptosis.

XKR8 XKR9

2.41e-051026225231987
Pubmed

Gcm2 is required for the differentiation and survival of parathyroid precursor cells in the parathyroid/thymus primordia.

CASR PTCH1

4.86e-051426217382312
Pubmed

L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.

CASR SLC13A2 TNFSF14

1.65e-0414326320424473
Pubmed

Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development.

CERS6 CERS4

1.86e-042726223096701
Pubmed

Morphology-based mammalian stem cell tests reveal potential developmental toxicity of donepezil.

CERS6 CERS4

1.86e-042726225269881
Pubmed

Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2.

CERS6 CERS4

2.15e-042926238485951
Pubmed

Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.

CASR RNF175 TNFSF14

6.72e-0423126321048031
GeneFamilyCERS class homeoboxes

CERS6 CERS4

1.40e-056182530
GeneFamilyBlood group antigens|XK related family

XKR8 XKR9

5.12e-0511182955
GeneFamilySolute carriers

SLC13A1 SLC13A2 SLC22A7 SLC5A3

5.39e-04395184752
GeneFamilyRing finger proteins

RNF121 RNF175

3.00e-0227518258
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

CASR SLC13A1 SLC13A2 SLC22A7

1.86e-0615426489a60a79d07466d7ad05888d10a72d3b1ab384af
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

CASR SLC13A1 SLC13A2 SLC22A7

1.86e-06154264f1fea1a87e977221fa125b62287368be9af4987d
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

CASR SLC13A1 SLC13A2 SLC22A7

1.86e-06154264b5604c0b0b9b283352a3f612f40883b9123475d1
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal-1|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

CASR SLC13A1 SLC13A2 SLC22A7

1.86e-06154264160b170a3ade8b246843c9854af332475c047ba0
ToppCellCOVID-19-APC-like-Alveolar_macrophages|COVID-19 / group, cell type (main and fine annotations)

XKR8 C1QTNF3 RNF175 DENND4B

1.96e-06156264735ade77cfa16b9386a0c7ec2bd14bd2e78a51ad
ToppCellE18.5-Immune-Immune_Myeloid-DC-cDC2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TNFSF14 DENND4B C2CD2L

1.25e-0416826393b7138f17aa14a6398c9b4ea7237781a0e19a66
ToppCellE18.5-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TNFSF14 DENND4B C2CD2L

1.25e-04168263e393553208617a023f1646169c892a87c95db3f5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM150B SLC13A1 SLC22A7

1.32e-04171263f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM238 SLC13A1 SLC13A2

1.38e-04174263e7cca4b6a3935fad61cf2a3d9984ab1ffa1a9447
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM238 SLC13A1 SLC13A2

1.38e-04174263ad5b56f0ace6455c033834b931ec870cc0dc9290
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC13A1 SLC13A2 SLC22A7

1.43e-041762631595dbeee336a81e581325d63208ec6262664ee9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC13A1 SLC13A2 SLC22A7

1.51e-04179263d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_proximal_straight_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC13A1 XKR9 GRK1

1.53e-04180263b34d933cdabf692f02eaaf65c2aaca1fb9510627
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM150B SLC13A1 SLC22A7

1.53e-041802631363b3254470f6ff98630d1df83a1bdbacc137e0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC13A1 SLC13A2 SLC22A7

1.58e-04182263e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC13A1 SLC13A2 SLC22A7

1.58e-041822634a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC13A1 SLC13A2 SLC22A7

1.58e-0418226357bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC13A1 SLC13A2 SLC22A7

1.61e-0418326385446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC13A1 SLC13A2 SLC22A7

1.61e-04183263d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC13A1 SLC13A2 SLC22A7

1.63e-041842639434731f651820b05335085582960f08fbf895de
ToppCellControl-Epithelial_alveolar-AT_2-AT2_Progenitor|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMEM238 SLC13A2 CERS4

1.66e-041852638ca1374501eca01d8468130b74d50abfd4329fbe
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC13A1 SLC13A2 SLC22A7

1.69e-04186263a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC13A1 SLC13A2 SLC22A7

1.71e-041872631b82920588f9e26ef1db244d452736d75fcfd342
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC13A1 SLC13A2 SLC22A7

1.71e-04187263c1e4c0345f9bfa0538730bad5ff3fa5240168b25
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CACNA2D1 PTCH1 SLC5A3

1.77e-04189263dc5164591dea45b420798b94dda211be03daa70c
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC13A1 SLC13A2 SLC22A7

1.85e-041922633e1a4cb0d83efd502c8613d41a1692bdda5860ed
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC13A1 SLC13A2 SLC22A7

1.97e-041962634ebcaac758ed01d918de9c1cd383a84457b615f3
ToppCellControl_saline-Epithelial_alveolar-AT_2-AT2|Control_saline / Treatment groups by lineage, cell group, cell type

TMEM238 SLC13A2 CERS4

2.00e-04197263f870a26f322668781e3d2832c5d9ef2c7c91011f
ToppCellCOVID-19-kidney-PCT-S3-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC13A1 SLC13A2 SLC22A7

2.03e-0419826336a60397f49f5381ae377155b73e1891448846b7
ToppCellcontrol-MAIT|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TMEM238 PTCH1 TNFSF14

2.03e-0419826313955a4026c97e11d94973ac87bf018f64a2616c
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CASR TMEM238 SLC5A3

2.09e-04200263ae91dc047dc80560ba298d8d21a772154fa2775d
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Serous|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RNF121 SLC13A2 DENND4B

2.09e-0420026361bae10c8b12196d9cee766897971b81cb897191
ToppCellcontrol-MAIT|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TMEM238 PTCH1 TNFSF14

2.09e-04200263aeea4bda2e38cc6db571ed2b47ce022d637619bd
Drug2-azaspiro[4.4]nonane

CACNA2D1 PTCH1

1.16e-055252CID000418904
DrugS-(+)-ibuprofen [51146-56-6]; Up 200; 19.4uM; PC3; HT_HG-U133A

DUOX2 C1QTNF3 PTCH1 C2CD2L

5.62e-051942546712_UP
Drug2-methyl-3-phenylpropionamide

CASR PTCH1 SLC13A1

7.49e-0575253CID000348285
Drugketorolac tromethamine

GCFC2 GRK1

1.20e-0415252CID000084003
Drugketorolac

GCFC2 GRK1

1.96e-0419252CID000003826
Drugmetoprolol

CACNA2D1 CASR PTCH1

2.04e-04105253CID000004171
DrugGdCl3

CACNA2D1 CASR SLC22A7

2.09e-04106253CID000061486
Drugcalyculin A

RNF121 CASR CERS6

2.59e-04114253ctd:C059041
Drugfluo-3

CACNA2D1 CASR SLC22A7

3.17e-04122253CID000104978
Drughypothiocyanite

DUOX2 GCFC2

3.42e-0425252CID000124984
Drug2-aminoethyl diphenylborinate

CACNA2D1 CASR GRK1

3.56e-04127253CID000001598
DrugSuccinic acid

SLC13A1 SLC13A2

3.70e-0426252DB00139
Drugoxcarbazepine

CACNA2D1 PTCH1

4.94e-0430252CID000034312
Drug1-methyladenosine

CASR GRK1

5.99e-0433252CID000027476
DrugVerteporfin [129497-78-5]; Down 200; 2.8uM; HL60; HT_HG-U133A

CERS6 PTCH1 SLC5A3

6.99e-041602536133_DN
DrugKodak CD4

GCFC2 NAGPA

7.53e-0437252CID000075383
Drugcarbamazepine

CACNA2D1 PTCH1 SLC13A2

9.68e-04179253CID000002554
Drugfura-2 acetoxymethyl ester

CACNA2D1 CASR

1.06e-0344252CID003364574
Druglissamine

PTCH1 NAGPA

1.06e-0344252CID005359521
DiseaseKohlschutter-Tonz syndrome (implicated_via_orthology)

SLC13A1 SLC13A2

5.80e-065232DOID:0111668 (implicated_via_orthology)
Diseasealcohol-related neurodevelopmental disorder (implicated_via_orthology)

SLC13A1 SLC13A2

1.62e-058232DOID:0050667 (implicated_via_orthology)
DiseaseRS-10-hydroxywarfarin to RS-warfarin ratio measurement

CERS6 GCFC2 TNFSF14

8.45e-05110233EFO_0803335
Diseasesphingomyelin measurement

CASR CERS6 CERS4

1.27e-03278233EFO_0010118
Diseasewhite matter microstructure measurement

TMEM150B CACNA2D1 PTCH1

3.33e-03390233EFO_0005674

Protein segments in the cluster

PeptideGeneStartEntry
WWYLLELGFYLSLLI

CERS4

181

Q9HA82
RKWWGLNLQFLLVFL

CASR

716

P41180
LQALGLLWFRYHNLW

DUOX2

251

Q9NRD8
MLWRQLIYWQLLALF

C1QTNF3

1

Q9BXJ4
VFAWLLQYARGLWLA

C2CD2L

26

O14523
QFWSGLKLFRNILLW

GCFC2

646

P16383
LWYIIGIQFLLLWLV

CACNA2D1

1081

P54289
LQWPLSYLAIFWILQ

AWAT1

16

Q58HT5
WWVFNLLLLLVQGLN

CERS6

301

Q6ZMG9
FWNLLWYFQRLRLPS

DENND4B

1301

O75064
LGSLYFLRFLQWKWL

GRK1

166

Q15835
LLALVGYLIRDWRWL

SLC22A7

246

Q9Y694
LLLSWIWLQWLFLGF

SLC13A1

296

Q9BZW2
AWLWLQILFLGFNFR

SLC13A2

281

Q13183
IGLLWALLLNWYLTV

TAS2R50

56

P59544
LGNVYFWLQLLLWRL

TMEM150B

126

A6NC51
GRWLLLRLALFGFLW

NAGPA

6

Q9UK23
LFWEQYIGLRHWLLL

PTCH1

1016

Q13635
AWEFNALLLLQLLGW

SLC5A3

81

P53794
LAVQGWFLLQLHWRL

TNFSF14

51

O43557
LYGQILDWLRYLVAW

RNF175

296

Q8N4F7
YGQLLDWLRYLVAWQ

RNF121

296

Q9H920
ALLVFLSLLGWILWY

TMEM238

76

C9JI98
VIYFLWNLLLLWPRV

XKR8

201

Q9H6D3
ALFLLLFLWLLGIIW

XKR9

231

Q5GH70
LSLFLFLWFILGNYW

TMEM272

111

A0A1B0GTI8