Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainCRIC_ras_sig

CNKSR1 CNKSR2

1.55e-053432PF10534
DomainCRIC

CNKSR1 CNKSR2

1.55e-053432PS51290
DomainCRIC_domain

CNKSR1 CNKSR2

1.55e-053432IPR017874
DomainSAM_1

CNKSR1 CNKSR2 BFAR

5.13e-0468433PF00536
DomainSAM

CNKSR1 CNKSR2 BFAR

1.09e-0388433SM00454
DomainSAM_DOMAIN

CNKSR1 CNKSR2 BFAR

1.36e-0395433PS50105
DomainSAM

CNKSR1 CNKSR2 BFAR

1.44e-0397433IPR001660
Domain-

CNKSR1 CNKSR2 BFAR

1.86e-031064331.10.150.50
DomainDEAD_ATP_HELICASE

DDX17 DDX5

2.31e-0331432PS00039
DomainSAM/pointed

CNKSR1 CNKSR2 BFAR

2.46e-03117433IPR013761
DomainRNA-helicase_DEAD-box_CS

DDX17 DDX5

2.61e-0333432IPR000629
DomainQ_MOTIF

DDX17 DDX5

3.28e-0337432PS51195
DomainRNA_helicase_DEAD_Q_motif

DDX17 DDX5

3.28e-0337432IPR014014
Domain-

A1BG HFE TREML4 MYCBP2 UMODL1 IL6R

3.90e-036634362.60.40.10
Domain-

CNKSR1 CNKSR2 NOS1

4.95e-031504332.30.42.10
DomainPDZ

CNKSR1 CNKSR2 NOS1

5.05e-03151433PS50106
DomainPDZ

CNKSR1 CNKSR2 NOS1

5.14e-03152433IPR001478
DomainIg-like_fold

A1BG HFE TREML4 MYCBP2 UMODL1 IL6R

5.28e-03706436IPR013783
Domain-

HELZ NLRP1 ABCA2 DDX17 DNAH9 DDX5

6.88e-037464363.40.50.300
Pubmed

The Ddx5 and Ddx17 RNA helicases are cornerstones in the complex regulatory array of steroid hormone-signaling pathways.

DDX17 DDX5

1.71e-06246224275493
Pubmed

Helicases DDX5 and DDX17 promote heterogeneity in HBV transcription termination in infected human hepatocytes.

DDX17 DDX5

1.71e-06246238782119
Pubmed

Involvement of RNA helicases p68 and p72 in colon cancer.

DDX17 DDX5

1.71e-06246217699760
Pubmed

Identification of novel pathway partners of p68 and p72 RNA helicases through Oncomine meta-analysis.

DDX17 DDX5

1.71e-06246218005418
Pubmed

The highly related DEAD box RNA helicases p68 and p72 exist as heterodimers in cells.

DDX17 DDX5

1.71e-06246212595555
Pubmed

CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling.

CNKSR1 CNKSR2

1.71e-06246218287031
Pubmed

Upregulation of DEAD box helicase 5 and 17 are correlated with the progression and poor prognosis in gliomas.

DDX17 DDX5

1.71e-06246232008867
Pubmed

The roles of DEAD box helicases in the life cycle of HIV-1.

DDX17 DDX5

1.71e-06246226312911
Pubmed

DDX56 cooperates with FMDV 3A to enhance FMDV replication by inhibiting the phosphorylation of IRF3.

IRF3 DDX5

1.71e-06246231445188
Pubmed

NOS1-dependent negative feedback regulation of the epithelial sodium channel in the collecting duct.

SCNN1A NOS1

1.71e-06246225391901
Pubmed

Identification of Undetected Monogenic Cardiovascular Disorders.

HFE GAA

1.71e-06246232792077
Pubmed

Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness.

DDX17 DDX5

5.13e-06346223022728
Pubmed

RNA helicase DDX5 suppresses IFN-I antiviral innate immune response by interacting with PP2A-Cβ to deactivate IRF3.

IRF3 DDX5

5.13e-06346233065113
Pubmed

RNA helicases DDX5 and DDX17 dynamically orchestrate transcription, miRNA, and splicing programs in cell differentiation.

DDX17 DDX5

5.13e-06346224910439
Pubmed

The DEAD-box protein p72 regulates ERalpha-/oestrogen-dependent transcription and cell growth, and is associated with improved survival in ERalpha-positive breast cancer.

DDX17 DDX5

5.13e-06346219718048
Pubmed

Dual role of the ddx5/ddx17 RNA helicases in the control of the pro-migratory NFAT5 transcription factor.

DDX17 DDX5

5.13e-06346222266867
Pubmed

The p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific manner.

DDX17 DDX5

5.13e-06346215298701
Pubmed

The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor.

DDX17 DDX5

1.03e-05446215660129
Pubmed

Integrative analysis of large-scale loss-of-function screens identifies robust cancer-associated genetic interactions.

DDX17 DDX5

1.03e-05446232463358
Pubmed

Role of the Rho GTPase-activating protein RICS in neurite outgrowth.

ARHGAP32 PPP6R3

1.03e-05446216716191
Pubmed

Identification of cytoplasmic proteins interacting with unliganded estrogen receptor α and β in human breast cancer cells.

DDX17 DDX5

1.03e-05446225604459
Pubmed

Transcription-dependent nucleolar cap localization and possible nuclear function of DExH RNA helicase RHAU.

DDX17 DDX5

1.71e-05546218279852
Pubmed

Identification of RNA helicases in human immunodeficiency virus 1 (HIV-1) replication - a targeted small interfering RNA library screen using pseudotyped and WT HIV-1.

DDX17 DDX5

1.71e-05546225701821
Pubmed

Distinct DDX DEAD-box RNA helicases cooperate to modulate the HIV-1 Rev function.

DDX17 DDX5

2.56e-05646223608157
Pubmed

The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiation.

DDX17 DDX5

2.56e-05646217011493
Pubmed

Sumoylation of p68 and p72 RNA helicases affects protein stability and transactivation potential.

DDX17 DDX5

3.58e-05746219995069
Pubmed

Pleiotropic effects of p300-mediated acetylation on p68 and p72 RNA helicase.

DDX17 DDX5

4.77e-05846220663877
Pubmed

Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer.

DDX17 DDX5

6.12e-05946224581491
Pubmed

Genetic modifiers of muscular dystrophy: implications for therapy.

ITGA7 NOS1

6.12e-05946216916601
Pubmed

Full activation of estrogen receptor alpha activation function-1 induces proliferation of breast cancer cells.

DDX17 DDX5

7.65e-051046212738788
Pubmed

KSHV Viral Protein Kinase Interacts with USP9X to Modulate the Viral Lifecycle.

DDX17 PPP6R3

7.65e-051046236995092
Pubmed

A catalogue of genes in mouse embryonal carcinoma F9 cells identified with expressed sequence tags.

KANSL1 CIART

9.34e-05114628743579
Pubmed

Expanded CUG repeats Dysregulate RNA splicing by altering the stoichiometry of the muscleblind 1 complex.

DDX17 DDX5

9.34e-051146221900255
Pubmed

Systematic Identification of Oncogenic EGFR Interaction Partners.

CNKSR2 DDX17

1.12e-041246227956147
Pubmed

Transcription factors, cAMP-responsive element modulator (CREM) and Tisp40, act in concert in postmeiotic transcriptional regulation.

DDX17 DDX5

1.12e-041246216595651
Pubmed

A network comprising short and long noncoding RNAs and RNA helicase controls mouse retina architecture.

DDX17 DDX5

1.12e-041246226041499
Pubmed

A CASPR1-ATP1B3 protein interaction modulates plasma membrane localization of Na+/K+-ATPase in brain microvascular endothelial cells.

DDX17 DDX5

1.32e-041346230792309
Pubmed

Nucleolar localization of DGCR8 and identification of eleven DGCR8-associated proteins.

DDX17 DDX5

1.32e-041346217765891
Pubmed

Synopsis of preterm birth genetic association studies: the preterm birth genetics knowledge base (PTBGene).

SCNN1A IL6R

1.32e-041346220484876
Pubmed

VHL negatively regulates SARS coronavirus replication by modulating nsp16 ubiquitination and stability.

IRF3 TARS3

1.54e-041446225732088
Pubmed

Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.

ACP7 SDHAF4

2.30e-041746221490949
Pubmed

Identification of novel human WW domain-containing proteins by cloning of ligand targets.

SCNN1A IL6R

2.58e-04184629169421
Pubmed

WWP2-WWP1 ubiquitin ligase complex coordinated by PPM1G maintains the balance between cellular p73 and ΔNp73 levels.

NLRP1 DDX17 DDX5

2.93e-049746325071155
Pubmed

An unappreciated role for RNA surveillance.

HFE RBPMS ZAN

3.39e-0410246314759258
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

A1BG ADAMTS13 SERPINA6 GAA

3.72e-0425746416335952
Pubmed

Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins.

DDX17 DDX5

3.89e-042246226420826
Pubmed

Quantitative-trait loci analysis of cocaine-related behaviours and neurochemistry.

SERPINA6 NOS1

5.45e-042646210591541
Pubmed

Role of the E3 ubiquitin-ligase Hakai in intestinal inflammation and cancer bowel disease.

DDX17 DDX5

5.88e-042746236266428
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

HELZ ARHGAP32 CNKSR2 DDX17 MYCBP2 NOS1 KCNF1

6.95e-04113946736417873
Pubmed

Autophagy negatively regulates cancer cell proliferation via selectively targeting VPRBP.

DDX17 DDX5

7.27e-043046222963397
Pubmed

Methylation of the DNA/RNA-binding protein Kin17 by METTL22 affects its association with chromatin.

DDX17 DDX5

7.27e-043046224140279
Pubmed

HJURP binds CENP-A via a highly conserved N-terminal domain and mediates its deposition at centromeres.

DDX17 DDX5

7.77e-043146220080577
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

SCNN1A CLCA1 KCNF1

8.36e-0413946316985003
Pubmed

rec-YnH enables simultaneous many-by-many detection of direct protein-protein and protein-RNA interactions.

RBPMS DDX17 GAA

8.89e-0414246330217970
Pubmed

Cdc37 interacts with the glycine-rich loop of Hsp90 client kinases.

DDX17 DDX5

9.35e-043446216611982
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

HFE ABCA2 ITGA7 MYCBP2 PRCP MICAL2 PPP6R3

9.49e-04120146735696571
Pubmed

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.

HFE ZAN

9.90e-043546219862010
Pubmed

RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.

DDX17 DDX5 PPP6R3

1.00e-0314846335676246
Pubmed

Tagging genes with cassette-exchange sites.

HELZ RBPMS DDX17 PPP6R3

1.00e-0333546415741177
Cytoband9q34

ABCA2 ADAMTS13

1.36e-03544629q34
GeneFamilySterile alpha motif domain containing

CNKSR1 CNKSR2 BFAR

5.47e-0488333760
GeneFamilyPDZ domain containing

CNKSR1 CNKSR2 NOS1

2.64e-031523331220
GeneFamilyDEAD-box helicases

DDX17 DDX5

2.66e-0342332499
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

LY75 PRCP

3.90e-0351332870
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HELZ SETD2 DDX17 KANSL1 MYCBP2 DDX5

5.05e-0820045612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCelldroplet-Lung-nan-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A HFE RBPMS TREML4

1.72e-05153454f6ef14d949107c08cb3690e26ec91e194cb43518
ToppCelldroplet-Lung-nan-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A HFE RBPMS TREML4

1.72e-051534546dcab3d50ab50051955204dc4e4a64c1ca855bcd
ToppCellfacs-Lung-Endomucin-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A HFE TREML4 IL6R

1.90e-051574540ad242320ada7bcb9e29548d3050bf4fd3a07115
ToppCellfacs-Lung-Endomucin-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A HFE TREML4 IL6R

1.90e-05157454fe4c9556806203e57522d1986754ebe5a20aa2de
ToppCellPosterior_cortex|World / BrainAtlas - Mouse McCarroll V32

ARHGAP32 CNKSR2 KCNF1 MICAL2

2.00e-0515945418e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCelldroplet-Spleen-nan-18m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A HFE TREML4 IL6R

2.37e-05166454f751cbd01d4978ded7755874ab60504f6291afd7
ToppCelldroplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCNN1A HFE RBPMS TREML4

2.48e-05168454d823979335ac6b5d1f062ebb741c759d2f919dbf
ToppCelldroplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HFE TREML4 PRCP IL6R

2.48e-0516845400cff4698db14e03ca1d1b409e5ed1ad23b12615
ToppCelldroplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCNN1A HFE RBPMS TREML4

2.48e-05168454f377ff4c066a9857ad14d245e56325ad220e22e1
ToppCelldroplet-Lung-18m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HFE TREML4 PRCP IL6R

2.54e-0516945490c00ab30e582b0e2a2be751e1fae9024cfb9ea6
ToppCelldroplet-Spleen-SPLEEN-1m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE RBPMS TREML4 KCNF1

2.60e-051704547cb7ad9ab064b6ea452545d145e5b1d4090cd4c1
ToppCelldroplet-Spleen-SPLEEN-1m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE RBPMS TREML4 KCNF1

2.60e-05170454db7cee7e518debb2cbe9eeae05d47e14b69cb8e3
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A HFE TREML4 DNAH9

2.60e-051704548e774af244cfe787fa0ea2b6be0c3c2d00bfe4fc
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A HFE TREML4 DNAH9

2.60e-05170454f5140eb9313c0d1bb31f8a761d9c062c56733a61
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A HFE RBPMS TREML4

2.66e-05171454355a27ea88410a84210f7e4298c7c4f90cf2f8a9
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE RBPMS TREML4 MICAL2

2.91e-05175454c1c722db42da9b8a2a46e516ddb83d9be5e2e504
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A HFE RBPMS TREML4

2.91e-05175454cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-B_cells-Pro-B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A1BG P2RY10 SLC22A16 UMODL1

3.18e-05179454223f0895da89c7606f637aef113912dd06f39c5a
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-B_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A1BG P2RY10 SLC22A16 UMODL1

3.25e-05180454cb6b11883f42c8beff07f899036c803d786ac6a3
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

P2RY10 BFAR CIART IL6R

3.46e-05183454f142b320023eef00b48d4820c46214c9794d37e7
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNKSR2 ZAN DNAH9 PTPRQ

3.54e-05184454ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNKSR2 ZAN DNAH9 PTPRQ

3.54e-051844542cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNKSR2 ZAN DNAH9 PTPRQ

3.54e-051844542b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_NK-NK_CD56bright_CD16-|lymph-node_spleen / Manually curated celltypes from each tissue

HELZ ABCA2 MICAL2 DDX5

3.77e-051874549000241566f48e435db9409b7255db68b68f6059
ToppCellfacs-Marrow-KLS-3m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP32 ABCA2 RBPMS GAA

3.93e-05189454533685a921a65d84107d8d33c43b4fffde019143
ToppCellfacs-Marrow-KLS-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP32 ABCA2 RBPMS GAA

3.93e-05189454dca56ab02bf0505f9a352ff907edaef30906d854
ToppCellfacs-Marrow-KLS-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP32 ABCA2 RBPMS GAA

4.01e-05190454a513c1e7df62c28128c932a68b252ee8f0255172
ToppCellfacs-Marrow-KLS-3m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP32 ABCA2 RBPMS GAA

4.18e-0519245403dcd9405d3d76fc7455066ba5d83c09cd17072d
ToppCell(0)_NK_cells-(0)_NK_CD160pos|(0)_NK_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

A1BG P2RY10 HELZ DDX17

4.44e-051954546cbeceb52bb207f3c074e57b5b3f7cfb24fd5877
ToppCellPBMC-Control-cDC_3|Control / Compartment, Disease Groups and Clusters

DDX17 LY75 PRCP IL6R

4.53e-0519645409d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SCNN1A ARHGAP32 RBPMS MICAL2

4.80e-051994545f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CNKSR2 ITGA7 NOS1 MICAL2

4.80e-05199454fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCellTracheal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_activated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

P2RY10 TREML4 LY75 IL6R

4.80e-051994547b3d4c62b11268c7c1599600d8a7b331287cf21a
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SCNN1A ARHGAP32 RBPMS MICAL2

4.80e-051994545cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

BFAR LY75 CIART

1.03e-0490453f1415181bad5e2cf87eedd8563c0f1d20adc4cce
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

BFAR LY75 CIART

1.29e-0497453332b4daf5106872dd891d9f9b5a891192d5d9aa8
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SCNN1A ZAN RTL1

1.59e-04104453b5ca6e589f414e549f4990fe334d4ee54829b298
ToppCellGlobus_pallidus|World / BrainAtlas - Mouse McCarroll V32

DDX17 ZAN PPP6R3

2.79e-0412645344b63f945d5bedf1a2ca1810e7e100276ea9dd89
ToppCelldroplet-Heart-nan-3m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P2RY10 TREML4 LY75

3.80e-04140453ab90f6f30d89761687f8836e3d327d143ce49ed4
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Malignant_Peripheral_Nerve_Sheath_Tumors|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

TARS3 ACP7 KCNF1

4.05e-04143453d1c8e15a8ae2094de2919e99188f9211b78c5abf
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ARHGAP32 CNKSR2 ADAMTS13

4.05e-041434535fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HFE NLRP1 IL6R

4.47e-0414845331a7c2b20970070b14d2b955020320a6f99db547
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE TREML4 IL6R

4.65e-0415045334774b015adecc2be56a471fda8994e89a6ad93e
ToppCelldroplet-Lung-nan-3m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE TREML4 PRCP

4.74e-04151453c743dc8758416a4f562d60c8fd2df7e659ab6951
ToppCellsevere_COVID-19-MAIT|World / disease group, cell group and cell class (v2)

CNKSR1 ABCA2 CIART

5.02e-0415445365ec7f7ef05c589903c4c9fe3849478c325fdc61
ToppCelldroplet-Liver-HEPATOCYTES-1m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TREML4 UMODL1 IL6R

5.02e-0415445366c93733116e31b65dfb4b0b00de5c39d19cdb84
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_1|343B / Donor, Lineage, Cell class and subclass (all cells)

A1BG NLRP1 ITGA7

5.12e-04155453a4ff78e2efc6fe9a513bb2b64e5848f2ce65a09f
ToppCelldroplet-Liver-HEPATOCYTES-1m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TREML4 UMODL1 IL6R

5.31e-04157453b527e88382c8d21188a0f222b3302523e8816dfc
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CNKSR2 ITGA7 AVPR1A

5.51e-04159453a75ab494959575143cefdaec99e7aee3f318d559
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

P2RY10 CNKSR2 SDHAF4

5.51e-04159453ba82d1f55dd77c4b2183981b76cab1480fba75ad
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CNKSR2 ITGA7 AVPR1A

5.51e-04159453cfb4a8c8aac34b1a857956d98382d487abcf5444
ToppCelldroplet-Liver-HEPATOCYTES-1m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TREML4 UMODL1 IL6R

5.61e-04160453a494001b1f6dec33624f98fa3c24bad6988d0425
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A HFE TREML4

5.72e-041614533f3a2148c8d65e6a06f8d8116a3aa58dda17d618
ToppCellCOVID-CD8-CD8_2|COVID / Condition, Cell_class and T cell subcluster

P2RY10 CNKSR2 ACP7

5.72e-04161453307dcc17475413cd9eb70c27bc447f938ee5723d
ToppCelldroplet-Heart-nan-24m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P2RY10 TREML4 LY75

5.72e-041614537e60001637ef0f6fc67ef8a36ab80ebb25b0b0ab
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ARHGAP32 CNKSR2 KCNF1

5.72e-04161453ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZAN DNAH9 PTPRQ

5.82e-04162453bf886e22ff2a20353499004b53f25fb9e6574896
ToppCelldroplet-Lung-3m-Hematologic-myeloid-non-classical_monocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCNN1A HFE TREML4

5.92e-04163453f6c8db5963ee1f8e0c2996f1aeecd58c00e9b099
ToppCellFrontal_cortex|World / BrainAtlas - Mouse McCarroll V32

CNKSR2 KCNF1 MICAL2

6.03e-04164453e09291711abf8680e78170328313719092b0142f
ToppCelldroplet-Lung-3m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCNN1A HFE TREML4

6.03e-04164453ea2897942ad72fba900c7ab354d6a9e203bf0e4a
ToppCell343B-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

P2RY10 LY75 NOS1

6.03e-04164453eae6d440877b292ad18dc4bd02802dda5b2f9c60
ToppCellfacs-Marrow-Granulocytes-24m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE TREML4 IL6R

6.14e-0416545311227bff52eed30b80937fdb1968d0b8e6d30365
ToppCelldroplet-Lung-nan-18m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE TREML4 PRCP

6.14e-04165453e32697321cef424c2ad4e11ee9da3e510d5ce505
ToppCellfacs-Marrow-Granulocytes-24m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE TREML4 IL6R

6.14e-04165453036f9749048e5e50769cc3210339bf4da469215d
ToppCelldroplet-Lung-nan-18m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE TREML4 PRCP

6.14e-041654530fbdd043e11aa8dbff4cd3a4da1b2feb49878a09
ToppCelldroplet-Spleen-nan-18m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A HFE TREML4

6.25e-04166453e841e62cb20235d6233f78f4155fb8c0ffb1ef1b
ToppCelldroplet-Spleen-nan-18m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A HFE TREML4

6.25e-041664533ca3ddb663644f0e7f70f9b75833bb54cd9191d3
ToppCelldroplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HFE RBPMS TREML4

6.25e-041664531a3a15d1fc76bb91d832cdc6e3da0a6140b94b75
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor|lymph-node_spleen / Manually curated celltypes from each tissue

RBPMS UMODL1 AVPR1A

6.36e-04167453cb396f3edb9e8fdc316091e8e193dbba50e0be0c
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCNN1A CNKSR2 MICAL2

6.36e-04167453a90f905ef38437752e2b0b71bd0322a184de1861
ToppCelldroplet-Lung-LUNG-30m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

P2RY10 ADAMTS13 LY75

6.47e-041684530e8b0e6399c6c82c9c0e546f7316f902de0765d3
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCNN1A HFE TREML4

6.47e-041684534b5be7c6662eceddf90a65015f12908278d1664e
ToppCelldroplet-Spleen-SPLEEN-1m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE RBPMS TREML4

6.47e-04168453f3b7a7df54988de77dcc7066e2fc1feb9c280b13
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCNN1A HFE TREML4

6.47e-04168453689c41f6e9f65381570991cc311cba49a57ec955
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE RBPMS TREML4

6.47e-04168453e979a4fbeb9f21048b47d69e6da75c57650697f2
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE TREML4 SERPINA6

6.58e-041694533f8aa6d2f9aa060ae1a0ea3eb47e794099fc2c2c
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-7|TCGA-Lung / Sample_Type by Project: Shred V9

BFAR RBPMS ARSL

6.58e-041694535f522a10b6ec24a353f53bec2f779a81cd5f9581
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A HFE TREML4

6.58e-04169453411556e93adcbb7e4d79b02f3dc72963ec8a0759
ToppCelldroplet-Lung-nan-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A HFE TREML4

6.58e-04169453c96e0f3241d13926dbee9f91c0c8c5bfa7479a0d
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE TREML4 SERPINA6

6.58e-0416945326de495c7562e0740689d0f78e803698e3e793db
ToppCelldroplet-Lung-LUNG-30m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A HFE TREML4

6.58e-0416945339b1acfd099abb9de18c29c05c7a67709ea76775
ToppCelldroplet-Lung-21m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCNN1A HFE TREML4

6.58e-04169453b059304543876f514d5c7214f1f0a2da00f10a67
ToppCelldroplet-Lung-21m-Hematologic-myeloid-non-classical_monocyte|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCNN1A HFE TREML4

6.58e-04169453945f737984c4de70a4e9c214053b005358053dd5
ToppCelldroplet-Spleen-nan-3m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE RBPMS TREML4

6.58e-0416945391cfff1ad559cc327c6bb71c98aa29f0b3642568
ToppCelldroplet-Lung-nan-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A HFE TREML4

6.58e-04169453ba023ee7bb165c2bfbefc2d969ff32ca1eeed33b
ToppCell10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-MEMP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

RBPMS TREML4 SDHAF4

6.58e-041694539a2fedee8ff90513bc2cbe2a65d07575ee8a0b70
ToppCelldroplet-Spleen-nan-3m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE RBPMS TREML4

6.58e-04169453972618e684321060c7af2429f853a6d639e8aae8
ToppCelldroplet-Spleen-nan-3m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE RBPMS TREML4

6.58e-041694538e5e513090e86ca29fb61dfd388014774c506914
ToppCelldroplet-Lung-nan-18m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE PRCP IL6R

6.69e-04170453545c755b057871b7a22221a049a63a61713dad1d
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid-macrophage|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE TREML4 SERPINA6

6.69e-04170453670027daec5a10dfa12246f1497b58db21d32a22
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZAN LY75 MYCBP2

6.81e-04171453845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCelldroplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCNN1A HFE TREML4

6.81e-0417145300739085fdbc4d64c9faacba2c2adeab580dd2b1
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SCNN1A IL6R PPP6R3

6.92e-04172453a9e13aa36087170dadca421ba9de588e5a1cf715
ToppCellmetastatic_Brain-Fibroblasts-Undetermined|Fibroblasts / Location, Cell class and cell subclass

SCNN1A CIART DNAH9

6.92e-04172453c3822ff7329c3ac38c68c5c38cd67c390682e2a6
ToppCelldroplet-Lung-nan-21m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A HFE TREML4

6.92e-0417245351bea97564a33f0060c546c9be4bf8bf8f1660f6
ToppCellfacs-BAT-Fat-18m-Myeloid-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HFE TREML4 IL6R

6.92e-0417245336fe66a8c0aecee7a19269be23210c0ed7abb155
ToppCellfacs-BAT-Fat-18m-Myeloid|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A TREML4 IL6R

6.92e-041724538e91831804a120037c71cd4e74af686f3c32d31c
ToppCelldroplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCNN1A HFE TREML4

6.92e-041724535f58ff6cac32546d07b2a49ed250b6c7aa417188
ToppCelldroplet-Lung-nan-21m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A HFE TREML4

6.92e-04172453be4dd4ba8d7a651677c797c25fd75f14e627415a
DrugStachydrine hydrochloride; Up 200; 22.2uM; PC3; HT_HG-U133A

HFE NLRP1 ADAMTS13 CLCA1 ITGA7 IL6R

2.98e-062004664469_UP
Diseaselymphocyte percentage of leukocytes

HELZ SETD2 ADAMTS13 RBPMS KANSL1 LY75 UMODL1

5.31e-05665447EFO_0007993
Diseaseabdominal obesity-metabolic syndrome (implicated_via_orthology)

DDX17 DDX5

9.71e-0510442DOID:0060611 (implicated_via_orthology)
Diseasemiddle temporal gyrus volume measurement, Alzheimer's disease biomarker measurement

CNKSR2 MYCBP2

1.68e-0413442EFO_0006514, EFO_0010316
Diseaseximenoylcarnitine (C26:1) measurement

SLC22A16 PPP6R3

1.68e-0413442EFO_0800543
Diseasecerotoylcarnitine (C26) measurement

SLC22A16 PPP6R3

1.68e-0413442EFO_0800542
Diseaserenovascular hypertension (biomarker_via_orthology)

AVPR1A NOS1

3.66e-0419442DOID:1591 (biomarker_via_orthology)
Diseasecystic fibrosis (is_implicated_in)

HFE NOS1

7.45e-0427442DOID:1485 (is_implicated_in)
DiseaseAlzheimer's disease (is_implicated_in)

HFE NOS1 IL6R

1.01e-03132443DOID:10652 (is_implicated_in)
Diseasemean corpuscular hemoglobin concentration

HFE RBPMS LY75 SLC22A16 IL6R GAA PPP6R3

1.16e-031105447EFO_0004528
Diseaseemphysema imaging measurement

CNKSR1 CNKSR2 MYCBP2

1.35e-03146443EFO_0007626

Protein segments in the cluster

PeptideGeneStartEntry
TLTSMWSPAVVLETW

UMODL1

736

Q5DID0
GSLPVTNTMELPWWV

ERVPABLB-1

86

P60509
LSNWMSWVLPIVSPL

nan

516

Q9N2K0
PVSWMPVIWSALSAV

ARSL

221

P51690
WTLQSWVPEMQDPQS

ADAMTS13

1406

Q76LX8
QMRWLPPSEATSQGW

RBPMS

176

Q93062
LMRWSPDNSVVIVTW

RIC1

311

Q4ADV7
MTVTWTTWVPTRSEV

ACP7

46

Q6ZNF0
LPAPWLSMAPVSWIT

A1BG

116

P04217
IIQTVRTNFPETWMW

OVOS1

616

Q6IE37
PDRQTLMWSATWPKE

DDX5

271

P17844
TPWKGMQSRENIWVP

C9orf131

451

Q5VYM1
RSTWSPTMVVLFRWV

NLRP1

776

Q9C000
QQWGVRPRPSWITTM

PRCP

396

P42785
EMERARWLWTTSVPP

KANSL1

926

Q7Z3B3
WQWSDRTPVSTIIMP

LY75

726

O60449
RTPWVSSRISSQMWL

HFE

71

Q30201
VSVIDMPPKVLSTWW

ARHGAP32

286

A7KAX9
SMTPTIPWSPNRQWD

HELZ

621

P42694
WVWIVPPMSGSITPV

NOS1

681

P29475
MATSWQSVLVKWDPP

PTPRQ

1391

Q9UMZ3
WSPEAMGTPWTESRS

IL6R

306

P08887
WSRSELKTVPQRMWS

BFAR

381

Q9NZS9
EWSWPWARTPRLSVM

ABCA2

946

Q9BZC7
PLMLSTSWTRITLWN

GAA

266

P10253
RQEPSMSWWPVSSAE

ITGA7

971

Q13683
IRPDRQTLMWSATWP

DDX17

346

Q92841
MVTSSIHAWETTPWR

DNAH9

1311

Q9NYC9
MTPSRLPWLLSWVSA

SDHAF4

1

Q5VUM1
SRWPSVTSQEWVFQM

SCNN1A

491

P37088
WLPTSGLWTVQAMDP

SERPINA6

11

P08185
FWWSLTPVNKRTMSP

MICAL2

1251

O94851
WCTWKTTISLRQPPM

P2RY10

216

O00398
SWPQDQPWTKRLVMV

IRF3

351

Q14653
APERWMVSSWLPSEV

RTL1

386

A6NKG5
WPFWLSPRQVMVIPV

TARS3

691

A2RTX5
TWWLYQMILSTVTVP

SLC22A16

266

Q86VW1
WWMKGSTPTQISEII

MYCBP2

4161

O75592
TQWPAMNLTWIHTTP

CIART

251

Q8N365
TWTMQPPQILLWDPS

CLCA1

521

A8K7I4
WWKSPAQCTRPTVMS

CLUHP3

121

Q96NS8
MEPVETWTPGKVATW

CNKSR1

1

Q969H4
EPVSKWSPSQVVDWM

CNKSR2

6

Q8WXI2
SPMWTLPWLPTSTVL

TREML4

136

Q6UXN2
ITRQTQWDPPTWESP

SETD2

2411

Q9BYW2
WDPMSVWTESENPTI

AVPR1A

316

P37288
VWSTEEPMPTKETGW

PPP6R3

706

Q5H9R7
HWNTQRPSWMLTTVT

ZAN

151

Q9Y493
SIPQSFWWAIITMTT

KCNF1

356

Q9H3M0