Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionTBP-class protein binding

CAND1 ESR1 NACA YEATS2

2.34e-05331024GO:0017025
GeneOntologyCellularComponentintraciliary transport particle B

IFT172 RABL2B RABL2A

1.37e-04211013GO:0030992
GeneOntologyCellularComponentsperm midpiece

IFT172 FSIP2 RABL2B RABL2A

2.61e-04641014GO:0097225
GeneOntologyCellularComponentintraciliary transport particle

IFT172 RABL2B RABL2A

3.28e-04281013GO:0030990
GeneOntologyCellularComponentactin-based cell projection

VIL1 MYO1D INPPL1 ADGRV1 PKHD1L1 NEDD4 PTPRZ1

4.05e-042781017GO:0098858
GeneOntologyCellularComponentsperm flagellum

IFT172 FSIP2 RABL2B RABL2A CATSPER1 AK1

6.06e-042141016GO:0036126
DomainRap_GAP

SIPA1L3 SIPA1 SIPA1L2

1.69e-0510993PF02145
DomainRap_GAP_dom

SIPA1L3 SIPA1 SIPA1L2

2.31e-0511993IPR000331
DomainRAPGAP

SIPA1L3 SIPA1 SIPA1L2

2.31e-0511993PS50085
DomainSPAR_C

SIPA1L3 SIPA1L2

8.32e-053992PF11881
DomainSIPA1L_C

SIPA1L3 SIPA1L2

8.32e-053992IPR021818
DomainTox-GHH_dom

TENM4 TENM1

1.66e-044992IPR028916
DomainTox-GHH

TENM4 TENM1

1.66e-044992PF15636
DomainTen_N

TENM4 TENM1

1.66e-044992IPR009471
DomainTen_N

TENM4 TENM1

1.66e-044992PF06484
DomainTENEURIN_N

TENM4 TENM1

1.66e-044992PS51361
DomainYD

TENM4 TENM1

2.75e-045992IPR006530
DomainEGF_extracell

RELN ADAM18 TENM4 TENM1

2.88e-0460994IPR013111
DomainEGF_2

RELN ADAM18 TENM4 TENM1

2.88e-0460994PF07974
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UBR2 HDAC5 IFT172 FSTL5 NEDD4 YEATS2 TENM4 SETD5 MACF1 SIPA1L2

3.53e-074071021012693553
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TRIO INPPL1 SIPA1L3 TAB3 NEDD4 FSIP2 SLC16A1 AASS SSX2IP MACF1 CRYBG3 SIPA1L2 DNMBP

1.48e-068611021336931259
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

TRIO INPPL1 SIPA1L3 SSX2IP MACF1 CRYBG3 SIPA1L2

2.92e-06209102736779422
Pubmed

RABL2 Is Required for Hepatic Fatty Acid Homeostasis and Its Dysfunction Leads to Steatosis and a Diabetes-Like State.

RABL2B RABL2A

8.52e-062102227732084
Pubmed

Genetic basis of hyperlysinemia.

PTPRZ1 AASS

8.52e-062102223570448
Pubmed

Octyl gallate markedly promotes anti-amyloidogenic processing of APP through estrogen receptor-mediated ADAM10 activation.

ESR1 ADAM10

8.52e-062102223977176
Pubmed

Analysis of relative gene dosage and expression differences of the paralogs RABL2A and RABL2B by Pyrosequencing.

RABL2B RABL2A

8.52e-062102220138207
Pubmed

The centriolar satellite protein SSX2IP promotes centrosome maturation.

SLC16A1 SSX2IP

8.52e-062102223816619
Pubmed

Novel mutations in TGM1 and ABCA12 cause autosomal recessive congenital ichthyosis in five Saudi families.

ABCA12 TGM1

8.52e-062102227061915
Pubmed

Two novel human RAB genes with near identical sequence each map to a telomere-associated region: the subtelomeric region of 22q13.3 and the ancestral telomere band 2q13.

RABL2B RABL2A

8.52e-062102210444334
Pubmed

Variants in RABL2A causing male infertility and ciliopathy.

RABL2B RABL2A

8.52e-062102233075816
Pubmed

Stabilization of estrogen receptor α by USP37 contributes to the progression of breast cancer.

ESR1 USP37

8.52e-062102236221793
Pubmed

EGCG functions through estrogen receptor-mediated activation of ADAM10 in the promotion of non-amyloidogenic processing of APP.

ESR1 ADAM10

8.52e-062102220849853
Pubmed

RABL2 positively controls localization of GPCRs in mammalian primary cilia.

RABL2B RABL2A

8.52e-062102230578315
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TRIO MFHAS1 INPPL1 SIPA1L3 PLXNB2 ACOX3 HEG1 SETD5 PLA2G4B NBEAL2 DEPDC5 SIPA1L2 DNMBP

2.14e-0511051021335748872
Pubmed

NEDD4 controls spermatogonial stem cell homeostasis and stress response by regulating messenger ribonucleoprotein complexes.

NEDD4 NANOS3

2.55e-053102228585553
Pubmed

PHB2 promotes SHIP2 ubiquitination via the E3 ligase NEDD4 to regulate AKT signaling in gastric cancer.

INPPL1 NEDD4

2.55e-053102238200519
Pubmed

Summary of mutations underlying autosomal recessive congenital ichthyoses (ARCI) in Arabs with four novel mutations in ARCI-related genes from the United Arab Emirates.

ABCA12 TGM1

2.55e-053102228236338
Pubmed

DC-SCRIPT is a novel regulator of the tumor suppressor gene CDKN2B and induces cell cycle arrest in ERα-positive breast cancer cells.

ZNF366 ESR1

2.55e-053102225663546
Pubmed

RapGAPs in brain: multipurpose players in neuronal Rap signalling.

SIPA1L3 SIPA1L2

2.55e-053102220576033
Pubmed

Gonadotropin-releasing hormone-mediated phosphorylation of estrogen receptor-alpha contributes to fosB expression in mouse gonadotrophs.

ESR1 TAF6L

2.55e-053102219574399
Pubmed

HTRA1 promoter polymorphism predisposes Japanese to age-related macular degeneration.

CFH HTR1A

2.55e-053102217438519
Pubmed

The E3 ubiquitin ligase NEDD4 mediates cell migration signaling of EGFR in lung cancer cells.

LAMP2 NEDD4

2.55e-053102229455656
Pubmed

Polymorphism in MIR4697 but not VPS13C, GCH1, or SIPA1L2 is associated with risk of Parkinson's disease in a Han Chinese population.

VPS13C SIPA1L2

5.09e-054102228380328
Pubmed

Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues.

TENM4 TENM1

5.09e-054102210225957
Pubmed

HTRA1 variant confers similar risks to geographic atrophy and neovascular age-related macular degeneration.

CFH HTR1A

5.09e-054102217426452
Pubmed

Identification of genes differentially expressed in association with metastatic potential of K-1735 murine melanoma by messenger RNA differential display.

SOX10 TENM4

5.09e-05410228912867
Pubmed

SOX10 is a novel oncogene in hepatocellular carcinoma through Wnt/β-catenin/TCF4 cascade.

SOX10 TCF7L2

5.09e-054102225001176
Pubmed

ZNF366 is an estrogen receptor corepressor that acts through CtBP and histone deacetylases.

ZNF366 ESR1

5.09e-054102217085477
Pubmed

All four members of the Ten-m/Odz family of transmembrane proteins form dimers.

TENM4 TENM1

5.09e-054102212000766
Pubmed

Genome-wide ENU mutagenesis to reveal immune regulators.

RABL2B RABL2A

5.09e-054102211567631
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

UBR2 MYO1D TRIO SIPA1L3 DHX38 POR DDOST TAB3 SORT1 PTPRZ1 SSX2IP CRYBG3

5.95e-0510491021227880917
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

HDAC5 MYO1D INPPL1 DHX38 YEATS2 MACF1 CRYBG3 SIPA1L2 DNMBP

6.03e-05588102938580884
Pubmed

Mapping of the bcl-2 oncogene on mouse chromosome 1.

CFH REN

8.47e-05510222895697
Pubmed

Dismissal of RNA Polymerase II Underlies a Large Ligand-Induced Enhancer Decommissioning Program.

ESR1 NEDD4

8.47e-055102230118678
Pubmed

Rabl2 GTP hydrolysis licenses BBSome-mediated export to fine-tune ciliary signaling.

RABL2B RABL2A

8.47e-055102233241915
Pubmed

Myocyte enhancer factor 2 and class II histone deacetylases control a gender-specific pathway of cardioprotection mediated by the estrogen receptor.

HDAC5 ESR1

8.47e-055102219893013
Pubmed

Mapping the gene for LTW-4, a 26,000 molecular weight major protein of mouse liver and kidney.

CFH REN

8.47e-05510226934364
Pubmed

The gene for the alpha 1 subunit of the skeletal muscle dihydropyridine-sensitive calcium channel (Cchl1a3) maps to mouse chromosome 1.

VIL1 REN

8.47e-05510221335956
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

VIL1 VPS13C ADGRV1 SSX2IP MACF1

8.84e-05152102534299191
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ABCA12 SIPA1 KIF20A TAF6L YEATS2 SLC16A1 SETD5 SSX2IP MACF1 CRYBG3 SIPA1L2 SLC4A11

1.07e-0411161021231753913
Pubmed

Characterization of a region-specific library of microclones in the vicinity of the Bcg and splotch loci on mouse chromosome 1.

VIL1 REN

1.27e-04610228188220
Pubmed

Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico.

TCF7L2 SLC16A1

1.27e-046102224390345
Pubmed

Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation.

SOX10 TCF7L2

1.27e-046102226955760
Pubmed

Multiple modification and protein interaction signals drive the Ring finger protein 11 (RNF11) E3 ligase to the endosomal compartment.

NEDD4 SORT1

1.27e-046102220676133
Pubmed

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.

TCF7L2 VPS13C

1.27e-046102220081857
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

TAB3 TENM1 MACF1 CRYBG3 SIPA1L2 DNMBP

1.30e-04263102634702444
Pubmed

RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.

CAND1 IFT172 RABL2B RABL2A

1.60e-0492102423055941
Pubmed

Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells.

SOX10 TCF7L2

1.77e-047102217875931
Pubmed

Monitoring α-synuclein ubiquitination dynamics reveals key endosomal effectors mediating its trafficking and degradation.

VPS13C NEDD4

1.77e-047102237315142
Pubmed

The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain.

TENM4 TENM1

1.77e-047102212915301
Pubmed

Receptor-like protein tyrosine phosphatase zeta/RPTP beta is expressed on tangentially aligned neurons in early mouse neocortex.

RELN PTPRZ1

1.77e-047102214757526
Pubmed

Tissue expression patterns identify mouse cilia genes.

DRC7 ARMC3 FAM81B IFT172

1.88e-0496102417971504
Pubmed

Differential regulation of estrogen receptor α expression in breast cancer cells by metastasis-associated protein 1.

HDAC5 ESR1

2.36e-048102224413532
Pubmed

Upg-2: a urinary pepsinogen variant located on chromosome 1 of the mouse.

CFH REN

2.36e-04810227165695
Pubmed

Mapping of Col3a1 and Col6a3 to proximal murine chromosome 1 identifies conserved linkage of structural protein genes between murine chromosome 1 and human chromosome 2q.

VIL1 REN

2.36e-04810221981051
Pubmed

Ndfip1 expression in developing neurons indicates a role for protein ubiquitination by Nedd4 E3 ligases during cortical development.

RELN NEDD4

2.36e-048102224036464
Pubmed

Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25.

TENM4 TENM1

2.36e-048102210331952
Pubmed

Phosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brain.

INPPL1 PIP5K1B

2.36e-048102220622009
Pubmed

A genetic map of mouse chromosome 1 near the Lsh-Ity-Bcg disease resistance locus.

VIL1 REN

2.36e-04810221970800
Pubmed

Linkage of genes for laminin B1 and B2 subunits on chromosome 1 in mouse.

CFH REN

2.36e-04810222993224
Pubmed

GPR37 Signaling Modulates Migration of Olfactory Ensheathing Cells and Gonadotropin Releasing Hormone Cells in Mice.

SOX10 RELN

2.36e-048102231143101
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

FSTL5 YEATS2 HEG1 MACF1

2.47e-04103102410574462
Pubmed

Prevalence of common disease-associated variants in Asian Indians.

CFH TCF7L2

3.03e-049102218248681
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

SOX10 TOR2A ADAM18 RC3H1 PLXNB2 NEDD4 TGM1 SETD5 PLA2G4B

3.04e-04730102934857952
Pubmed

Identification of kidney mesenchymal genes by a combination of microarray analysis and Sall1-GFP knockin mice.

RABL2B RABL2A TENM4

3.62e-0447102315172686
Pubmed

The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs.

CAND1 POR LAMP2 DDOST SLC16A1 NBEAL2

3.72e-04320102628685749
Pubmed

Aurora kinase-A overexpression in mouse mammary epithelium induces mammary adenocarcinomas harboring genetic alterations shared with human breast cancer.

TCF7L2 ESR1

3.77e-0410102227624071
Pubmed

Reelin Can Modulate Migration of Olfactory Ensheathing Cells and Gonadotropin Releasing Hormone Neurons via the Canonical Pathway.

SOX10 RELN

3.77e-0410102230127721
Pubmed

Establishment of a molecular genetic map of distal mouse chromosome 1: further definition of a conserved linkage group syntenic with human chromosome 1q.

CFH REN

3.77e-041010223384439
Pubmed

A molecular genetic approach to gld "autoimmune" disease.

CFH REN

3.77e-041010223416634
Pubmed

Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.

TENM4 TENM1

3.77e-0410102238713721
Pubmed

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.

GLS2 REN SORT1 SOHLH2 SLC4A11

4.14e-04212102519521566
Pubmed

Nervous-tissue-specific elimination of microtubule-actin crosslinking factor 1a results in multiple developmental defects in the mouse brain.

RELN MACF1

4.60e-0411102220170731
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

MUC19 CCDC168 FSIP2 YEATS2

4.84e-04123102426912792
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

TRIO NACA POR TAB3 TENM4 SLC16A1 TENM1 MACF1 AK1 CRYBG3 SIPA1L2

5.20e-0411391021136417873
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

HDAC5 SIPA1L3 ADGRV1 TENM4 MACF1

5.42e-04225102512168954
Pubmed

Transcriptional regulation by the repressor of estrogen receptor activity via recruitment of histone deacetylases.

HDAC5 ESR1

5.51e-0412102215140878
Pubmed

Redundant and additive functions of the four Lef/Tcf transcription factors in lung epithelial progenitors.

TCF7L2 LAMP2

5.51e-0412102232414917
Pubmed

Cell autonomous roles of Nedd4 in craniofacial bone formation.

SOX10 NEDD4

5.51e-0412102226681395
Pubmed

The ubiquitin ligase Nedd4 regulates craniofacial development by promoting cranial neural crest cell survival and stem-cell like properties.

SOX10 NEDD4

5.51e-0412102224080509
Pubmed

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.

TCF7L2 VPS13C

5.51e-0412102221873549
Pubmed

The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base.

RABL2B RABL2A

5.51e-0412102228625565
Pubmed

Identification and mapping of six microdissected genomic DNA probes to the proximal region of mouse chromosome 1.

VIL1 REN

5.51e-041210221358796
Pubmed

A protein interaction landscape of breast cancer.

UBR2 CAND1 PHF19 TRIO ESR1 SIPA1L3 SIPA1 MACF1

5.70e-04634102834591612
Pubmed

Autosomal Recessive Congenital Ichthyosis

ABCA12 TGM1

6.50e-0413102220301593
Pubmed

Control of astrocyte progenitor specification, migration and maturation by Nkx6.1 homeodomain transcription factor.

SOX10 RELN

6.50e-0413102225285789
Pubmed

Conditional deletion of pten leads to defects in nerve innervation and neuronal survival in inner ear development.

SOX10 AK1

6.50e-0413102223393595
Pubmed

Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.

KIF6 MFHAS1

6.50e-0413102218846501
Pubmed

The intracellular domain of teneurin-1 induces the activity of microphthalmia-associated transcription factor (MITF) by binding to transcriptional repressor HINT1.

TENM1 MACF1

6.50e-0413102225648896
Pubmed

Genetic dissection of plexin signaling in vivo.

RELN PLXNB2

8.72e-0415102224469813
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

MYO1D TRIO VPS13C SIPA1L3 TAB3 AASS SSX2IP SIPA1L2 DNMBP

9.24e-04853102928718761
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CAND1 VPS13C NACA ADGRV1 NBEAL2 DEPDC5 DNMBP

9.64e-04529102714621295
Pubmed

14-3-3ε mediates the cell fate decision-making pathways in response of hepatocellular carcinoma to Bleomycin-induced DNA damage.

UBR2 CAND1 TAB3

9.80e-0466102323472066
Pubmed

New loci associated with kidney function and chronic kidney disease.

IFT172 SORT1 PIP5K1B

9.80e-0466102320383146
Pubmed

SZT2 dictates GATOR control of mTORC1 signalling.

LAMP2 DEPDC5

9.95e-0416102228199315
Pubmed

Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation.

TCF7L2 ESR1

9.95e-0416102219487454
Pubmed

Gene deletion mutants reveal a role for semaphorin receptors of the plexin-B family in mechanisms underlying corticogenesis.

RELN PLXNB2

9.95e-0416102219948886
Pubmed

Functional genomics identifies a mechanism for estrogen activation of the retinoic acid receptor alpha1 gene in breast cancer cells.

HDAC5 ESR1

9.95e-0416102215831516
Pubmed

Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.

RELN PLXNB2

1.13e-0317102211683995
InteractionSIPA1 interactions

ESR1 SIPA1L3 SIPA1 KIF20A SIPA1L2

1.60e-0641985int:SIPA1
InteractionPFN1 interactions

CAND1 HDAC5 TRIO VPS13C ESR1 INPPL1 ADAM10 NEDD4 MACF1 CRYBG3 SIPA1L2 DNMBP

6.70e-065099812int:PFN1
Cytoband8p23.1

MFHAS1 ZNF705D ZNF705G ZNF705B

4.01e-0415410248p23.1
Cytoband7q31.3

PTPRZ1 AASS

5.04e-041510227q31.3
GeneFamilyRAB like GTPases

RABL2B RABL2A

1.42e-045692394
CoexpressionGSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_MAC_DN

ESR1 DHX38 PLXNB2 DDOST HEG1 AASS MACF1

9.44e-06199977M5240
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 MUC19 ADGRV1 PKHD1L1 PTPRZ1 AASS

1.77e-061601016c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 MUC19 ADGRV1 PKHD1L1 PTPRZ1 AASS

1.77e-06160101625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRRC63 ARMC3 FAM81B ADAM10 VGLL1 SLC4A11

3.60e-0618110166a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DRC7 KIF6 ARMC3 FAM81B RABL2B RABL2A

3.60e-061811016dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN ABCA12 ADGRV1 PKHD1L1 TENM4 TENM1

3.96e-0618410162cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN ABCA12 ADGRV1 PKHD1L1 TENM4 TENM1

3.96e-061841016ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN ABCA12 ADGRV1 PKHD1L1 TENM4 TENM1

3.96e-0618410162b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCOPD-Epithelial-Mesothelial|Epithelial / Disease state, Lineage and Cell class

CFH PKHD1L1 TGM1 HEG1 SLC16A1 SIPA1L2

4.48e-061881016159d63ecc3653a7449fc6acefd6ef0464845260e
ToppCellParenchymal-NucSeq-Stromal-Mesofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFH PKHD1L1 TGM1 ZNF676 SLC16A1 PTPRZ1

5.52e-061951016a52685f76eca269a7d2de8dfc317439483e233fa
ToppCellASK428-Epithelial-Transformed_epithelium|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

CFH PKHD1L1 ZNF676 HEG1 SLC16A1 SSX2IP

5.52e-061951016c750602c765a51075ba6ede78e3ba80b62374481
ToppCellParenchymal-NucSeq-Stromal-Mesofibroblastic-Mesothelia|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CFH PKHD1L1 TGM1 ZNF676 SLC16A1 PTPRZ1

5.52e-061951016224deeba2f60def6543a55bb4f5ee6c7fdab3f02
ToppCellSepsis-Leuk-UTI-Lymphocyte-B-Plasmablast|Leuk-UTI / Disease, condition lineage and cell class

MYO1D PKHD1L1 TAB3 KIF20A SMOX DNMBP

6.21e-0619910161b17e6d5e6b994dec65efae2667f4f1f438161b1
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-8|TCGA-Kidney / Sample_Type by Project: Shred V9

ZNF705EP ZNF705D ZNF705G ORC5 ZNF705B

9.04e-061231015967f20fcb27c9989de93f4183038334105910175
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c06-MKI67|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYO1D PKHD1L1 KIF20A TAS2R42 TGM1

2.14e-05147101522d71cf92b957e5a8aa63b13157626d013d6752b
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DRC7 KIF6 ARMC3 FAM81B PTPRZ1

2.76e-0515510155f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DRC7 KIF6 ARMC3 FAM81B PTPRZ1

2.76e-0515510150944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RELN TGM1 SOHLH2 PTPRZ1 VGLL1

3.31e-051611015da9eecf919866a9c579d7a707a996cf335213134
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RELN TGM1 SOHLH2 PTPRZ1 VGLL1

3.31e-051611015d431625c32f59a6b552191f3adc5198bd16ad5cf
ToppCellfacs-GAT-Fat-24m-Epithelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIL1 ADGRV1 KIF20A SORT1 OTC

4.66e-051731015815ba48a9222ea09ba8005e2d2f7c5addf118ad1
ToppCellfacs-GAT-Fat-24m-Epithelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIL1 ADGRV1 KIF20A SORT1 OTC

4.66e-05173101598e464d9e6d6b69421e9e4041b638b6825247f60
ToppCellwk_20-22-Epithelial-PNS|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SOX10 RELN FSTL5 PTPRZ1 SIPA1L2

4.66e-05173101517b1a6b0318925d5d920f2c0a791745b9587ebef
ToppCellfacs-GAT-Fat-24m-Epithelial-epithelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIL1 ADGRV1 KIF20A SORT1 OTC

4.66e-0517310153e6f0a08eddfd61871f7a85acccf6d539af6ebda
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH VPS13C NEDD4 HEG1 MACF1

5.06e-051761015749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

CFH RELN ARMC3 SIPA1L2 SLC4A11

5.48e-051791015e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCellwk_20-22-Epithelial-PNS-intermediate_Schwann|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SOX10 RELN FSTL5 TAB3 SIPA1L2

6.25e-0518410154e3ba64692868563a579902aa9c6f88cab5bce26
ToppCellCOPD-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

CFH PKHD1L1 TGM1 HEG1 SLC16A1

6.41e-05185101523579988036fc1925992c31919750f9b3fe9f790
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFH RELN ARMC3 SIPA1L2 SLC4A11

6.41e-05185101534fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFH RELN ARMC3 SIPA1L2 SLC4A11

6.41e-0518510158816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

VIL1 ARMC3 FAM81B SSX2IP SMOX

6.57e-051861015107bc473f5e57238390f8e0ab9f7263a8f93948c
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

VIL1 ARMC3 FAM81B SSX2IP SMOX

6.57e-05186101513a9ddcf93b0c4319ab9d484af5e2056e9754caa
ToppCellIPF-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

MYO1D ZNF366 SIPA1L3 TENM4 HSH2D

6.91e-05188101547bb6caf84f70a1cda7d09803afdfd5182772e66
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1D TRIO SIPA1L3 ADAM10 SLC4A11

6.91e-05188101563a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellCOPD-Epithelial-Mesothelial|COPD / Disease state, Lineage and Cell class

CFH PKHD1L1 TGM1 HEG1 SLC16A1

7.09e-05189101579bb2593ad5d17f94b17972884241f03a0f43770
ToppCellmild_COVID-19-Platelet|World / disease group, cell group and cell class (v2)

VIL1 ARMC3 FAM81B SSX2IP SMOX

7.09e-051891015038ec3c266b89416bb5b774ba522d916394961da
ToppCellASK428-Epithelial-Transformed_epithelium|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

CFH PKHD1L1 ZNF676 HEG1 SLC16A1

7.09e-05189101587189275234b5d59484c58acbb14a09903f2b578
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

KIF6 ARMC3 FAM81B RABL2B RABL2A

7.09e-0518910153e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

UBR2 VPS13C LAMP2 ADAM10 MACF1

7.45e-0519110159454f642c3621370fa23640b631301346b300950
ToppCelldroplet-Marrow-BM-1m-Hematologic-erythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MFHAS1 PKHD1L1 SLC16A1 SSX2IP SMOX

7.45e-051911015d78d4fbb0b8317dbf14e32182466a432abef3e93
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN FSTL5 HEG1 TENM1 PIP5K1B

7.64e-051921015bf1943715085c4124b1675888b0615c9500ec888
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ARMC3 FAM81B PTPRZ1 AK1 SLC4A11

7.82e-051931015c3522693439c23830d8a3f20854539ccb7a666e0
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ARMC3 PTPRZ1 AASS TENM1 AK1

8.21e-05195101532ec72103faccc9e37c0ecedff1998e7df6a19f6
ToppCellsevere-Lymphocytic-Plasmablast|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MYO1D PKHD1L1 DDOST TENM4 SMOX

8.21e-05195101543ff1eed563c647bc5b7b06ffe136210653c3a83
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DRC7 ARMC3 FAM81B IFT172 RABL2A

8.41e-051961015a37ba02446eef5d1fab703204583f6550a8ec3e1
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DRC7 ARMC3 FAM81B IFT172 RABL2A

8.41e-051961015a156840330630e518bc85633dded6f2c3ead3b30
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DRC7 ARMC3 FAM81B IFT172 RABL2A

8.41e-05196101589ea4d2086e1c769c5a87f1471a6cd4acabcfe33
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LRRC63 SOX10 MYO1D LAMP2 SORT1

8.41e-05196101537a5f9f3988778655580bd0383811bb4930c1551
ToppCellInfluenza-Influenza_Severe-Lymphocyte-B-Plasmablast|Influenza_Severe / Disease, condition lineage and cell class

MYO1D CCDC168 PKHD1L1 KIF20A IGHV4-4

8.62e-0519710159108edafbf5744ed65f556bcbbf819a9b71176a9
ToppCellcontrol-Myeloid-CD16_Monocytes|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TCF7L2 PHF19 NACA PLXNB2 HEG1

8.62e-051971015cdb2866d5a8fbf39847309124479ad49c88852d4
ToppCellControl-Control-Lymphocyte-T/NK-NK_activated|Control / Disease, condition lineage and cell class

ESR1 YEATS2 HEG1 MACF1 HSH2D

8.83e-05198101576d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCellmild-Myeloid-CD16_Monocytes|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TCF7L2 PHF19 NACA PLXNB2 HEG1

8.83e-051981015ba97ff6e9d400b53ad013dce54afd7154a0f4fc9
ToppCellfacs-Tongue-nan-3m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RC3H1 LAMP2 ADAM10 NEDD4 SLC16A1

9.04e-0519910158d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCellPBMC-Control-cDC_0|Control / Compartment, Disease Groups and Clusters

TCF7L2 INPPL1 PLXNB2 CATSPER1 NBEAL2

9.04e-051991015ebf03979ef56e978d72db475bb635b43b9cbe402
ToppCell(10)_Ciliated|World / shred by cell type by condition

DRC7 ARMC3 FAM81B RABL2B RABL2A

9.25e-0520010151b6a8025bd2746b626040058c122b1be3ab2fa61
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1--L1-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

FSTL5 SIPA1L3 TENM1 PIP5K1B CRYBG3

9.25e-052001015f3c710f0fc8a7bfb5371d1aff6e3d8f266953153
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-OPC_related-OPC|GW26 / Sample Type, Dataset, Time_group, and Cell type.

SOX10 TCF7L2 KIF20A PTPRZ1 AASS

9.25e-05200101502594c1edbc9f2cf831639cd83363abd2551cb94
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

FSTL5 SIPA1L3 TENM1 PIP5K1B CRYBG3

9.25e-05200101570a06fd7fb8de2c8ec3e3182e4476ced049daeae
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-OPC_related|GW26 / Sample Type, Dataset, Time_group, and Cell type.

SOX10 TCF7L2 KIF20A PTPRZ1 AASS

9.25e-05200101546521d83b917b0357601db8783c8da6b73730d60
ToppCellBiopsy_IPF-Epithelial-Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

ARMC3 FAM81B IFT172 RABL2B RABL2A

9.25e-052001015bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCell(09)_Interm._secr.>cil.|World / shred by cell type by condition

DRC7 ARMC3 FAM81B RABL2B RABL2A

9.25e-0520010153305e14dba12e94da42f0414fdc7a2c8caf0a183
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ADAM10 NEDD4 HEG1 MACF1 SIPA1L2

9.25e-05200101579e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1|Neuronal / cells hierarchy compared to all cells using T-Statistic

FSTL5 SIPA1L3 TENM1 PIP5K1B CRYBG3

9.25e-0520010151639982d9d994918f7912d12d9d7cfcbc9da4145
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN ESR1 FSTL5 VGLL1

1.28e-041131014feb3c6a7723263d58e5ce020a0097fedfcf78ca8
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Nefl_(Neurofilament_state)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ABCA12 MUC19 CCDC168

1.55e-0446101337ea73d291e35b6865bd3ea4857275a6e5b299d1
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Nefl_(Neurofilament_state)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ABCA12 MUC19 CCDC168

1.55e-0446101369e9c8cbae3d15bd0823b8c6e48a9d2b9815296b
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Nr2f2_Necab1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN HTR1A FSTL5 ACOD1

1.83e-041241014298ff8bd8f0459f44ce8a8aea889c6f1cf84ac5f
ToppCelldroplet-Heart-HEART-1m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACOX3 TAF6L ORC5 RBAK

2.00e-041271014983489a69d3b1f1fe21110a862ac1dba53e9d31c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

VIL1 ESR1 SOHLH2 PLA2G4B

3.15e-0414310148f897278f9ccc82ae35e4f30c5f930b2a3eb509d
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_2-Sox4-POLYDENDROCYTE_(Neurogenesis_(SGZ)_(Ppp2r2b))|Hippocampus / BrainAtlas - Mouse McCarroll V32

LRRC63 DNMBP SLC4A11

3.60e-04611013f470e0a6b3d5062e71635d643bce15f85ffda8ab
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(MGE-derived_cortical_interneurons--Martinotti_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PKHD1L1 ACOD1 TAS2R42

3.77e-04621013a20620a8869721ea62984c2022ee1b484b455824
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Nr2f2_(MGE-derived_cortical_interneurons--Martinotti_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PKHD1L1 ACOD1 TAS2R42

3.77e-04621013ee694c06bcd924b4ddf744178ba3a99e04eed51b
ToppCellCOVID-19_Mild|World / 5 Neutrophil clusters in COVID-19 patients

RELN ZNF366 CCDC168 ADGRV1

3.96e-0415210142ff0980dfd8d430cca14649151d856edef115720
ToppCellIIH-CD8-exh_CD4|IIH / Condition, Cell_class and T cell subcluster

LRRC63 IFT172 SIPA1L3 ADGRV1

4.16e-041541014a2f51a3c5455fe2483e438375ea856afce8262fe
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DRC7 KIF6 ARMC3 FAM81B

4.16e-0415410149ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CAND1 ESR1 REN RBAK

4.16e-041541014e65e4636646164610f33f7bbac0d879a3ea55986
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DRC7 KIF6 ARMC3 FAM81B

4.16e-04154101458072ce422d09f2de602580325eaac6c4ec6c136
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DRC7 MAGEA11 ZNF705EP SMOX

4.27e-04155101429c4e9947bb4f7e257ed5c3bcf21bd67f88d473f
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SOX10 FSIP2 ZNF676 PTPRZ1

4.27e-04155101477fdae85d36efb776db977eb424b32487ef222e4
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFH ZNF705D SIPA1L2 SLC4A11

4.37e-041561014dd41ed918b07fa248da458a629b3c53cb7ea8764
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFH ZNF705D SIPA1L2 SLC4A11

4.37e-041561014abf9dd075b1ca8f613c660cc82f8a5af071fb6ab
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)-|343B / Donor, Lineage, Cell class and subclass (all cells)

TGM1 SOHLH2 PTPRZ1 VGLL1

4.48e-041571014dd08dc19d434e94a194076c462ee273c682abf55
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)|343B / Donor, Lineage, Cell class and subclass (all cells)

TGM1 SOHLH2 PTPRZ1 VGLL1

4.48e-04157101470fd6c46db4250c7de5c4686a9500689402737f6
ToppCellBAL-Severe-cDC_4|Severe / Compartment, Disease Groups and Clusters

IFT172 TENM4 AASS PIP5K1B

4.59e-04158101473f66689ef59f71b14cb7141ca5951cc47fe57c1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCF7L2 PLXNB2 CATSPER1 SIPA1L2

4.59e-0415810141635a85fc73c544028418087f36d28957dd4f458
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFH CCDC168 SIPA1L2 SLC4A11

4.59e-041581014e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFH CCDC168 SIPA1L2 SLC4A11

4.59e-041581014d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCF7L2 PLXNB2 CATSPER1 SIPA1L2

4.59e-04158101480841dadfa53bcde36a3e486408a095f78e772eb
ToppCellLeuk-UTI-Lymphocyte-B-Plasmablast|Leuk-UTI / Disease, Lineage and Cell Type

MYO1D PKHD1L1 KIF20A SMOX

4.59e-04158101405a29c2d5506a25ccdfa4c6a86e9188977a18272
ToppCellControl-Epithelial_airway|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DRC7 ARMC3 ADGRV1 PTPRZ1

4.59e-04158101435aee1c3b92169e73569331022833cb44ab7e7e8
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ZNF366 CATSPER1 TENM4 AASS

4.59e-0415810141bf692f1e85f677cd62805437b7a59cfaf3b0449
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

TGM1 HEG1 NBEAL2 IGHV4-4

4.81e-04160101458ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCellCV-Mild-4|CV / Virus stimulation, Condition and Cluster

TAB3 NANOS3 PIP5K1B SIPA1L2

4.81e-041601014be89efeeecb0de96ce136a7a62738f15dc0badb2
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLS2 ABCA12 MUC19 ACOD1

4.92e-041611014b9a17f41426bf715f30bf544a6795afaf37a3aa6
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLS2 ABCA12 MUC19 ACOD1

4.92e-041611014f7a89c481f789f624102857be722c95fbeb47595
ToppCell15-Distal-Immune-Immune|Distal / Age, Tissue, Lineage and Cell class

DRC7 PKHD1L1 CATSPER1 HSH2D

5.04e-041621014e190c496ed1e206b86566edfee23c99a99fe90d0
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH SOX10 PTPRZ1 SLC4A11

5.16e-041631014a1fbefe53523a9879a4d4b493071059798b5f917
ToppCell5'-Airway_Nasal_SMG-Epithelial|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH SOX10 PTPRZ1 SLC4A11

5.16e-041631014454a5e87e2f9f66e38cc5aa1b433c47b54c9be42
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH SOX10 PTPRZ1 SLC4A11

5.16e-041631014d9bd9d90cfa4e85d5ea51f8f3ee14a700571f508
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH SOX10 PTPRZ1 SLC4A11

5.16e-041631014f6847f47a8856c0d4136c1af317432d45eccfde9
ToppCellE12.5-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RELN SIPA1 ACOD1 NBEAL2

5.16e-041631014c21114826bee1b05b411984326fef6b6e0d05316
ToppCell5'-Airway_Nasal_SMG|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH SOX10 PTPRZ1 SLC4A11

5.16e-041631014d8450bf9c6d2ec5dd1472952c9e65f82f995337a
DrugDiflunisal [22494-42-4]; Up 200; 16uM; HL60; HG-U133A

TCF7L2 INPPL1 NACA ADAM10 NEDD4 SLC16A1 SSX2IP REV1

1.96e-061969781990_UP
DrugVerteporfin [129497-78-5]; Down 200; 2.8uM; HL60; HT_HG-U133A

POR LAMP2 PLXNB2 ADAM10 SLC16A1 NBEAL2 MACF1

5.61e-061609776133_DN
DiseaseDepression, Bipolar

RELN HTR1A HDAC5 FSTL5 TENM4

4.70e-0679915C0005587
DiseaseFVC change measurement, response to placebo

RELN ORC5 SMOX

7.94e-0613913EFO_0008344, EFO_0010339
DiseaseBipolar Disorder

RELN TCF7L2 HTR1A HDAC5 ESR1 FSTL5 REN NEDD4 TENM4

1.70e-05477919C0005586
DiseaseAutosomal Dominant Lateral Temporal Lobe Epilepsy

RELN DEPDC5

2.82e-053912C1838062
DiseaseIchthyosis Congenita I

ABCA12 TGM1

5.62e-054912C4551630
DiseaseHarlequin Fetus

ABCA12 TGM1

5.62e-054912C0239849
Diseasebeta-defensin 104 measurement

CFH ZNF705G

5.62e-054912EFO_0801416
DiseaseIchthyosis Congenita II

ABCA12 TGM1

5.62e-054912C3536797
Diseaseleukemia inhibitory factor measurement

CFH SMOX

5.62e-054912EFO_0801764
Diseaseautosomal recessive congenital ichthyosis 1 (is_implicated_in)

ABCA12 TGM1

5.62e-054912DOID:0060656 (is_implicated_in)
DiseaseCollodion Fetus

ABCA12 TGM1

5.62e-054912C3543867
DiseaseManic Disorder

RELN HDAC5 FSTL5 TENM4

7.02e-0571914C0024713
DiseaseC-reactive protein measurement

UBR2 TCF7L2 OR9G1 GLS2 MFHAS1 IFT172 VPS13C CCDC168 OR9G9 ACOD1 YEATS2 SETD5 MACF1

8.26e-0512069113EFO_0004458
DiseaseCongenital ichthyosis

ABCA12 TGM1

9.35e-055912C0020758
DiseaseManic

RELN HDAC5 FSTL5 TENM4

1.01e-0478914C0338831
DiseaseStage IV Skin Melanoma

ADAM18 ADAM10

1.96e-047912C1321872
DiseaseNeonatal sepsis

VIL1 USP37

2.60e-048912HP_0040187
Diseaseage at diagnosis, osteonecrosis

RELN ABCA12 ORC5

3.43e-0444913EFO_0004259, EFO_0004918
DiseaseFuchs endothelial corneal dystrophy

CFH TCF7L2

4.17e-0410912Orphanet_98974
Diseasedepressive disorder (is_marker_for)

HTR1A REN

4.17e-0410912DOID:1596 (is_marker_for)
DiseaseCongenital Nonbullous Ichthyosiform Erythroderma

ABCA12 TGM1

5.08e-0411912C0079154
DiseaseCongenital ichthyosis of skin

ABCA12 TGM1

5.08e-0411912cv:C0020758
Diseaselymphangioleiomyomatosis (is_marker_for)

ESR1 SLC16A1

6.08e-0412912DOID:3319 (is_marker_for)
Diseasebitter alcoholic beverage consumption measurement

RELN TCF7L2 ORC5 SETD5

7.79e-04133914EFO_0010092
Diseasecreatinine measurement

CFH VIL1 TCF7L2 CAND1 PDE7A SIPA1L3 POR ADGRV1 PLXNB2 PIP5K1B

9.89e-049959110EFO_0004518
DiseaseCongenital total cataract

SIPA1L3 DNMBP

1.10e-0316912C0266539
DiseaseMental Depression

RELN HTR1A HDAC5 ESR1 REN

1.16e-03254915C0011570
DiseasePsychoses, Substance-Induced

HTR1A ESR1

1.24e-0317912C0033941
Diseasesmoking status measurement, systolic blood pressure

MFHAS1 SIPA1 TENM4 NANOS3

1.41e-03156914EFO_0006335, EFO_0006527
Diseasebrain connectivity measurement

SOX10 KIF6 MFHAS1 ADGRV1 NEDD4 TENM4

1.51e-03400916EFO_0005210
Diseasesucrose liking measurement

RELN ORC5

1.72e-0320912EFO_0010157
DiseaseMood Disorders

RELN HTR1A ESR1 SMOX

1.84e-03168914C0525045
DiseasePsychoses, Drug

HTR1A ESR1

1.90e-0321912C0033937
DiseaseOvarian Failure, Premature

SOHLH2 NANOS3

1.90e-0321912C0085215
Diseasetype 2 diabetes mellitus (is_implicated_in)

KIF6 TCF7L2 ESR1 INPPL1

1.97e-03171914DOID:9352 (is_implicated_in)
DiseaseDepressive disorder

RELN HTR1A HDAC5 ESR1 REN

2.04e-03289915C0011581
Diseasetraumatic brain injury (biomarker_via_orthology)

LAMP2 ADAM10

2.48e-0324912DOID:0081292 (biomarker_via_orthology)
Diseasepseudotumor cerebri

OR9G1 OR9G9

2.91e-0326912EFO_1001132
DiseaseL lactate dehydrogenase measurement

CFH TENM4

2.91e-0326912EFO_0004808
Diseasemyeloperoxidase measurement

CFH HSH2D

2.91e-0326912EFO_0005243
DiseaseNeurodevelopmental Disorders

TCF7L2 TRIO SETD5

3.01e-0393913C1535926
Diseasemiddle cerebral artery infarction (biomarker_via_orthology)

HDAC5 PTPRZ1 AK1

3.01e-0393913DOID:3525 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
SSYLHGDYVQSTSQL

CATSPER1

311

Q8NEC5
TSKLHSSLKSAYHQY

CRYBG3

2226

Q68DQ2
SSLKSAYHQYLQTSQ

CRYBG3

2231

Q68DQ2
AVYSSGSERHLTYIQ

ACOX3

131

O15254
SNKVLDYDTSHIYTG

ADAM10

91

O14672
YSGCSLSYTNSHVEK

SSX2IP

596

Q9Y2D8
SYLTTKEHLLLYGSI

ABCA12

1431

Q86UK0
LVYTYNETGSLHSVS

ADAM18

71

Q9Y3Q7
TKYAEIYGISSAHTL

AASS

706

Q9UDR5
LSLHYKTLGSNATYI

ADGRV1

1396

Q8WXG9
NLASYTKKHHTSSVY

DNMBP

501

Q6XZF7
NLSLKYSQTGYLSSS

ARMC3

551

Q5W041
SSQESYAHGTKLSYT

CFH

886

P08603
YTSVYSHTTRNSAGK

NANOS3

116

P60323
TKSINISDYSPYGTH

RC3H1

906

Q5TC82
SSHLTSVTLYYGSIL

OR9G1

241

Q8NH87
YSYSKIISSIHAISS

OR7A5

216

Q15622
LSTYALTLYKHTATV

RABL2A

51

Q9UBK7
LSTYALTLYKHTATV

RABL2B

51

Q9UNT1
HQYEVSSSLGYTSTR

DEPDC5

541

O75140
LVFLSSYGKSQHYSS

SLC16A1

281

P53985
SHSYVLVTSLNLSYD

MAGEA11

286

P43364
TLLSKGSYQTSHQFI

NEDD4

286

P46934
LQARYYSIASSSKVH

POR

451

P16435
QSALSYLHESGKLLY

MFHAS1

701

Q9Y4C4
IYHSGSTNYNPSLKS

IGHV4-4

71

A0A075B6R2
KYGYTHLSTGDLLRS

AK1

31

P00568
IYTSVLKHSGSYTSV

FSIP2

6256

Q5CZC0
QSTALTHKQSYYSIA

CAND1

786

Q86VP6
TDHATYKAGYLSTNT

PLXNB2

201

O15031
AGSTSSHSLQKYYIT

ESR1

571

P03372
GSTIPYQYKHITTCS

MUC19

8356

Q7Z5P9
YLTLQEHYSSLKGLT

OTC

176

P00480
KTNHYLATLYKNTSV

PDE7A

266

Q13946
ATTISSSSLYVNEHY

PIP5K1B

476

O14986
NYSRGSTVHTAYLVL

MRGPRD

16

Q8TDS7
LQKDSSKIYTTHISY

KIF6

131

Q6ZMV9
YKTVTISDHGTVTYN

LAMP2

61

P13473
YAISISTLGTDYVHK

GLS2

226

Q9UI32
GYTYQHISRDLSATV

LRRC63

186

Q05C16
SYIKISNSSHSEYSS

HEG1

586

Q9ULI3
NLSSSDSPYHYTKVT

PLA2G4B

726

P0C869
ISTTTHYNRIGTKYN

PTPRZ1

461

P23471
SSHLTSVTLYYGSIL

OR9G9

241

P0C7N8
RLGYTHLYSSTQVSV

DDOST

396

P39656
SHSHVGYTLSYKAQS

HSH2D

61

Q96JZ2
HTSYAETLGKLETQY

MACF1

651

Q9UPN3
HITLDTLSYSSYKVP

RELN

506

P78509
LYITKVTTTHVGNYT

FSTL5

306

Q8N475
LSSGTRVVLKSHYGY

IFT172

341

Q9UG01
YQSGFKSIHDSLSSL

FAM81B

406

Q96LP2
ACTISKDHGYTIYST

HTR1A

186

P08908
HLYSSTTVLKYQKGN

DRC7

171

Q8IY82
HIASQYSKIYSSNIS

ACOD1

51

A6NK06
KKAYTESLHGYTLSN

CCDC168

4986

Q8NDH2
NSHGETVKTLYLSYL

ERCC6L2

446

Q5T890
QTVHSEYHTLLYGTS

HDAC5

741

Q9UQL6
LASHLYTTYRLGKTV

TAS2R42

71

Q7RTR8
SSLTDDLLKYYHQVT

TAF6L

151

Q9Y6J9
YLDDYHTKRTSSLVS

SLC4A11

506

Q8NBS3
YSKSLDRHLYTTTGG

SORT1

386

Q99523
GTGKSYVSSLLAHYL

TOR2A

96

Q8N2E6
HSVAYLPYTASSLSK

TAB3

346

Q8N5C8
YGHTASGKTYVTQTL

ORC5

36

O43913
SSYKHNGTELTLRYS

REN

136

P00797
QVTYSLHLYSVNGKL

NBEAL2

2626

Q6ZNJ1
HGISRTLTLVESNYY

GIN1

86

Q9NXP7
SVASYILASHNGISY

TENT5D

66

Q8NEK8
TDSTGTHSLYTTYKD

SIPA1L2

661

Q9P2F8
AKLYSVHGYASTISA

SIPA1L2

1311

Q9P2F8
KTDSTGTHSLYTMYQ

SIPA1L3

676

O60292
NGLSTVSHDYLKGSY

INPPL1

176

O15357
EKSVYSTHNYGTTQR

SETD5

36

Q9C0A6
KTDSTGTHSLYTTYQ

SIPA1

386

Q96FS4
THLYNHTSSEITSLY

TENM1

2281

Q9UKZ4
GTGKSYVSSLLAHYL

TOR2A

96

Q5JU69
YIILAIHKTASSLSY

VIL1

46

P09327
SHLVSLGYQISKSYI

ZNF705A

41

Q6ZN79
SSTLTYYKSIHTGEK

ZNF676

181

Q8N7Q3
YYSRSKTTHIIATNL

REV1

81

Q9UBZ9
IYTYGVTNSGKTHTI

KIF20A

156

O95235
SQKSYLTVHYRTHSG

RBAK

661

Q9NYW8
QSGSTHYSAYKTIEH

TCF7L2

131

Q9NQB0
THRKYYSTTHGALLS

SMOX

521

Q9NWM0
SQIAYTSLSLPHYGS

SOX10

376

P56693
SLSHLKSSITNYFGA

PHF19

531

Q5T6S3
LYLFDTTGKHLYTQS

TENM4

1586

Q6N022
SSEITSLYYDLQGHL

TENM4

2331

Q6N022
GILEHQYKESTTYIS

VPS13C

2596

Q709C8
KTTQLTQYLHEDGYT

DHX38

561

Q92620
HLEANTSTLYYLVSG

PKHD1L1

2961

Q86WI1
SHLVSLGYQISKSYI

ZNF705EP

41

A8MWA4
SHLVSLGYQISKSYI

ZNF705G

41

A8MUZ8
SHLVSLGYQISKSYI

ZNF705B

41

P0CI00
SHLVSLGYQISKSYI

ZNF705D

41

P0CH99
TSSSGHYISDVYDIK

USP37

901

Q86T82
SYTSKYNLVTHILGH

ZNF366

261

Q8N895
KLHLYLSVTFYTGVS

TGM1

611

P22735
ALSLNSLHTVRYYSK

SOHLH2

356

Q9NX45
LALYKTLHQYTGSAL

UBR2

1481

Q8IWV8
HYKKLYVSRGSASTS

VGLL1

211

Q99990
HYSISYSDLGEATLK

TRIO

2731

O75962
GGISQHLTYTSYILK

YEATS2

841

Q9ULM3
RLSTANTYSYHKVDL

JMJD8

96

Q96S16
LQKSLSSYNYIHVGA

MYO1D

221

O94832
SSYNYIHVGAQLKSS

MYO1D

226

O94832
TSLILKSSPNATYHY

NACA

411

E9PAV3