| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | RNA polymerase II cis-regulatory region sequence-specific DNA binding | SOX1 DACH1 SKOR1 CCAR1 HOXA13 ZNF384 POU4F1 CDX2 SIX4 GMEB2 NKX2-1 GLI2 MAZ FOXD1 SMAD4 | 1.18e-07 | 1244 | 48 | 15 | GO:0000978 |
| GeneOntologyMolecularFunction | RNA polymerase II transcription regulatory region sequence-specific DNA binding | SOX1 DACH1 SKOR1 CCAR1 HOXA13 ZNF384 NCOR1 POU4F1 CDX2 SIX4 GMEB2 NKX2-1 GLI2 MAZ FOXD1 SMAD4 | 1.46e-07 | 1459 | 48 | 16 | GO:0000977 |
| GeneOntologyMolecularFunction | cis-regulatory region sequence-specific DNA binding | SOX1 DACH1 SKOR1 CCAR1 HOXA13 ZNF384 POU4F1 CDX2 SIX4 GMEB2 NKX2-1 GLI2 MAZ FOXD1 SMAD4 | 1.56e-07 | 1271 | 48 | 15 | GO:0000987 |
| GeneOntologyMolecularFunction | DNA-binding transcription factor activity, RNA polymerase II-specific | SOX1 DACH1 SKOR1 HOXA13 ZNF384 POU4F1 CDX2 SIX4 GMEB2 NKX2-1 GLI2 MAZ FOXD1 SMAD4 | 3.60e-06 | 1412 | 48 | 14 | GO:0000981 |
| GeneOntologyMolecularFunction | DNA-binding transcription activator activity, RNA polymerase II-specific | 6.36e-06 | 560 | 48 | 9 | GO:0001228 | |
| GeneOntologyMolecularFunction | transcription coregulator activity | 6.55e-06 | 562 | 48 | 9 | GO:0003712 | |
| GeneOntologyMolecularFunction | DNA-binding transcription activator activity | 6.93e-06 | 566 | 48 | 9 | GO:0001216 | |
| GeneOntologyMolecularFunction | transcription corepressor activity | 1.75e-05 | 229 | 48 | 6 | GO:0003714 | |
| GeneOntologyMolecularFunction | chromatin binding | 3.44e-04 | 739 | 48 | 8 | GO:0003682 | |
| GeneOntologyMolecularFunction | sequence-specific mRNA binding | 9.43e-04 | 19 | 48 | 2 | GO:1990825 | |
| GeneOntologyMolecularFunction | protein-macromolecule adaptor activity | 1.57e-03 | 1160 | 48 | 9 | GO:0030674 | |
| GeneOntologyMolecularFunction | phosphatidylinositol kinase activity | 1.77e-03 | 26 | 48 | 2 | GO:0052742 | |
| GeneOntologyMolecularFunction | TBP-class protein binding | 2.85e-03 | 33 | 48 | 2 | GO:0017025 | |
| GeneOntologyMolecularFunction | RNA polymerase II-specific DNA-binding transcription factor binding | 3.17e-03 | 417 | 48 | 5 | GO:0061629 | |
| GeneOntologyMolecularFunction | lipid kinase activity | 4.37e-03 | 41 | 48 | 2 | GO:0001727 | |
| GeneOntologyMolecularFunction | molecular adaptor activity | 4.51e-03 | 1356 | 48 | 9 | GO:0060090 | |
| GeneOntologyBiologicalProcess | negative regulation of DNA-templated transcription | SOX1 DACH1 SKOR1 CCAR1 NCOR1 IRF2BPL POU4F1 DR1 CHD3 CDX2 SIX4 SPEN TBL1XR1 NKX2-1 GLI2 MAZ FOXD1 SMAD4 TBL1X | 9.61e-11 | 1399 | 48 | 19 | GO:0045892 |
| GeneOntologyBiologicalProcess | negative regulation of RNA biosynthetic process | SOX1 DACH1 SKOR1 CCAR1 NCOR1 IRF2BPL POU4F1 DR1 CHD3 CDX2 SIX4 SPEN TBL1XR1 NKX2-1 GLI2 MAZ FOXD1 SMAD4 TBL1X | 1.14e-10 | 1413 | 48 | 19 | GO:1902679 |
| GeneOntologyBiologicalProcess | negative regulation of transcription by RNA polymerase II | SOX1 DACH1 SKOR1 NCOR1 IRF2BPL POU4F1 DR1 CHD3 CDX2 SPEN TBL1XR1 NKX2-1 GLI2 MAZ SMAD4 TBL1X | 9.15e-10 | 1053 | 48 | 16 | GO:0000122 |
| GeneOntologyBiologicalProcess | positive regulation of transcription by RNA polymerase II | SOX1 HOXA13 ZNF384 IRF2BPL POU4F1 CDX2 SIX4 ARID3A TBL1XR1 NKX2-1 GLI2 ZMIZ2 MAZ FOXD1 SMAD4 TBL1X | 4.76e-08 | 1390 | 48 | 16 | GO:0045944 |
| GeneOntologyBiologicalProcess | cell fate specification | 3.98e-07 | 123 | 48 | 6 | GO:0001708 | |
| GeneOntologyBiologicalProcess | neuron fate commitment | 2.21e-06 | 91 | 48 | 5 | GO:0048663 | |
| GeneOntologyBiologicalProcess | neuron fate specification | 2.71e-06 | 42 | 48 | 4 | GO:0048665 | |
| GeneOntologyBiologicalProcess | kidney mesenchyme development | 6.48e-06 | 16 | 48 | 3 | GO:0072074 | |
| GeneOntologyBiologicalProcess | cell fate commitment | 1.23e-05 | 338 | 48 | 7 | GO:0045165 | |
| GeneOntologyBiologicalProcess | nephrogenic mesenchyme development | 1.59e-05 | 3 | 48 | 2 | GO:0072076 | |
| GeneOntologyBiologicalProcess | diencephalon development | 5.69e-05 | 90 | 48 | 4 | GO:0021536 | |
| GeneOntologyBiologicalProcess | central nervous system neuron differentiation | 1.46e-04 | 217 | 48 | 5 | GO:0021953 | |
| GeneOntologyBiologicalProcess | cell fate specification involved in pattern specification | 1.47e-04 | 8 | 48 | 2 | GO:0060573 | |
| GeneOntologyBiologicalProcess | ventral spinal cord interneuron specification | 1.47e-04 | 8 | 48 | 2 | GO:0021521 | |
| GeneOntologyBiologicalProcess | hindgut morphogenesis | 1.89e-04 | 9 | 48 | 2 | GO:0007442 | |
| GeneOntologyBiologicalProcess | morphogenesis of a branching epithelium | 2.16e-04 | 236 | 48 | 5 | GO:0061138 | |
| GeneOntologyBiologicalProcess | regulation of mRNA splicing, via spliceosome | 2.30e-04 | 129 | 48 | 4 | GO:0048024 | |
| GeneOntologyBiologicalProcess | hindgut development | 2.36e-04 | 10 | 48 | 2 | GO:0061525 | |
| GeneOntologyBiologicalProcess | morphogenesis of a branching structure | 3.25e-04 | 258 | 48 | 5 | GO:0001763 | |
| GeneOntologyBiologicalProcess | ventral spinal cord interneuron fate commitment | 3.45e-04 | 12 | 48 | 2 | GO:0060579 | |
| GeneOntologyBiologicalProcess | cell fate commitment involved in pattern specification | 3.45e-04 | 12 | 48 | 2 | GO:0060581 | |
| GeneOntologyBiologicalProcess | regulation of alternative mRNA splicing, via spliceosome | 3.51e-04 | 59 | 48 | 3 | GO:0000381 | |
| GeneOntologyBiologicalProcess | regulation of cellular response to growth factor stimulus | 3.70e-04 | 412 | 48 | 6 | GO:0090287 | |
| GeneOntologyBiologicalProcess | metanephric mesenchyme development | 4.07e-04 | 13 | 48 | 2 | GO:0072075 | |
| GeneOntologyBiologicalProcess | luteinizing hormone secretion | 4.74e-04 | 14 | 48 | 2 | GO:0032275 | |
| GeneOntologyBiologicalProcess | ventral spinal cord interneuron differentiation | 4.74e-04 | 14 | 48 | 2 | GO:0021514 | |
| GeneOntologyBiologicalProcess | regulation of mRNA processing | 4.96e-04 | 158 | 48 | 4 | GO:0050684 | |
| GeneOntologyBiologicalProcess | axon guidance | 5.12e-04 | 285 | 48 | 5 | GO:0007411 | |
| GeneOntologyBiologicalProcess | neuron projection guidance | 5.20e-04 | 286 | 48 | 5 | GO:0097485 | |
| GeneOntologyBiologicalProcess | branching involved in ureteric bud morphogenesis | 5.33e-04 | 68 | 48 | 3 | GO:0001658 | |
| GeneOntologyBiologicalProcess | regulation of mRNA metabolic process | 5.43e-04 | 443 | 48 | 6 | GO:1903311 | |
| GeneOntologyBiologicalProcess | transforming growth factor beta receptor superfamily signaling pathway | 5.56e-04 | 445 | 48 | 6 | GO:0141091 | |
| GeneOntologyBiologicalProcess | animal organ morphogenesis | SOX1 HOXA13 POU4F1 CDX2 SIX4 SHROOM2 NKX2-1 GLI2 FOXD1 SMAD4 | 5.73e-04 | 1269 | 48 | 10 | GO:0009887 |
| GeneOntologyBiologicalProcess | ureteric bud morphogenesis | 6.83e-04 | 74 | 48 | 3 | GO:0060675 | |
| GeneOntologyBiologicalProcess | interneuron migration | 7.05e-04 | 17 | 48 | 2 | GO:1904936 | |
| GeneOntologyBiologicalProcess | mesonephric tubule morphogenesis | 7.96e-04 | 78 | 48 | 3 | GO:0072171 | |
| GeneOntologyBiologicalProcess | regionalization | 8.07e-04 | 478 | 48 | 6 | GO:0003002 | |
| GeneOntologyBiologicalProcess | alternative mRNA splicing, via spliceosome | 8.26e-04 | 79 | 48 | 3 | GO:0000380 | |
| GeneOntologyBiologicalProcess | cell surface receptor protein serine/threonine kinase signaling pathway | 8.43e-04 | 482 | 48 | 6 | GO:0007178 | |
| GeneOntologyBiologicalProcess | suckling behavior | 8.84e-04 | 19 | 48 | 2 | GO:0001967 | |
| GeneOntologyBiologicalProcess | spinal cord dorsal/ventral patterning | 9.81e-04 | 20 | 48 | 2 | GO:0021513 | |
| GeneOntologyBiologicalProcess | nephron tubule morphogenesis | 1.09e-03 | 87 | 48 | 3 | GO:0072078 | |
| GeneOntologyBiologicalProcess | BMP signaling pathway | 1.13e-03 | 197 | 48 | 4 | GO:0030509 | |
| GeneOntologyBiologicalProcess | branching morphogenesis of an epithelial tube | 1.15e-03 | 198 | 48 | 4 | GO:0048754 | |
| GeneOntologyBiologicalProcess | nephron epithelium morphogenesis | 1.17e-03 | 89 | 48 | 3 | GO:0072088 | |
| GeneOntologyBiologicalProcess | male sex differentiation | 1.17e-03 | 199 | 48 | 4 | GO:0046661 | |
| GeneOntologyBiologicalProcess | gonadotropin secretion | 1.19e-03 | 22 | 48 | 2 | GO:0032274 | |
| GeneOntologyBiologicalProcess | spinal cord patterning | 1.19e-03 | 22 | 48 | 2 | GO:0021511 | |
| GeneOntologyBiologicalProcess | regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | 1.24e-03 | 347 | 48 | 5 | GO:0090092 | |
| GeneOntologyBiologicalProcess | nephron morphogenesis | 1.24e-03 | 91 | 48 | 3 | GO:0072028 | |
| GeneOntologyBiologicalProcess | sex differentiation | 1.32e-03 | 352 | 48 | 5 | GO:0007548 | |
| GeneOntologyBiologicalProcess | pattern specification process | 1.32e-03 | 526 | 48 | 6 | GO:0007389 | |
| GeneOntologyBiologicalProcess | renal tubule morphogenesis | 1.33e-03 | 93 | 48 | 3 | GO:0061333 | |
| GeneOntologyBiologicalProcess | regulation of RNA splicing | 1.36e-03 | 207 | 48 | 4 | GO:0043484 | |
| GeneOntologyBiologicalProcess | somite development | 1.37e-03 | 94 | 48 | 3 | GO:0061053 | |
| GeneOntologyBiologicalProcess | metanephros development | 1.41e-03 | 95 | 48 | 3 | GO:0001656 | |
| GeneOntologyBiologicalProcess | mRNA splicing, via spliceosome | 1.42e-03 | 358 | 48 | 5 | GO:0000398 | |
| GeneOntologyBiologicalProcess | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | 1.42e-03 | 358 | 48 | 5 | GO:0000377 | |
| GeneOntologyBiologicalProcess | RNA splicing, via transesterification reactions | 1.49e-03 | 362 | 48 | 5 | GO:0000375 | |
| GeneOntologyBiologicalProcess | cell morphogenesis | 1.53e-03 | 1194 | 48 | 9 | GO:0000902 | |
| GeneOntologyBiologicalProcess | response to BMP | 1.56e-03 | 215 | 48 | 4 | GO:0071772 | |
| GeneOntologyBiologicalProcess | cellular response to BMP stimulus | 1.56e-03 | 215 | 48 | 4 | GO:0071773 | |
| GeneOntologyBiologicalProcess | central nervous system neuron development | 1.59e-03 | 99 | 48 | 3 | GO:0021954 | |
| GeneOntologyBiologicalProcess | reproductive structure development | 1.91e-03 | 383 | 48 | 5 | GO:0048608 | |
| GeneOntologyBiologicalProcess | axonogenesis | 1.92e-03 | 566 | 48 | 6 | GO:0007409 | |
| GeneOntologyBiologicalProcess | lens morphogenesis in camera-type eye | 1.93e-03 | 28 | 48 | 2 | GO:0002089 | |
| GeneOntologyBiologicalProcess | dorsal/ventral pattern formation | 1.98e-03 | 107 | 48 | 3 | GO:0009953 | |
| GeneOntologyBiologicalProcess | ureteric bud development | 1.98e-03 | 107 | 48 | 3 | GO:0001657 | |
| GeneOntologyBiologicalProcess | reproductive system development | 2.02e-03 | 388 | 48 | 5 | GO:0061458 | |
| GeneOntologyBiologicalProcess | mesonephric tubule development | 2.14e-03 | 110 | 48 | 3 | GO:0072164 | |
| GeneOntologyBiologicalProcess | mesonephric epithelium development | 2.14e-03 | 110 | 48 | 3 | GO:0072163 | |
| GeneOntologyBiologicalProcess | nephron tubule development | 2.14e-03 | 110 | 48 | 3 | GO:0072080 | |
| GeneOntologyBiologicalProcess | kidney morphogenesis | 2.20e-03 | 111 | 48 | 3 | GO:0060993 | |
| GeneOntologyBiologicalProcess | mesonephros development | 2.31e-03 | 113 | 48 | 3 | GO:0001823 | |
| GeneOntologyBiologicalProcess | renal tubule development | 2.49e-03 | 116 | 48 | 3 | GO:0061326 | |
| GeneOntologyBiologicalProcess | prostate gland epithelium morphogenesis | 2.67e-03 | 33 | 48 | 2 | GO:0060740 | |
| GeneOntologyBiologicalProcess | prostate gland morphogenesis | 2.84e-03 | 34 | 48 | 2 | GO:0060512 | |
| GeneOntologyBiologicalProcess | endocrine process | 2.94e-03 | 123 | 48 | 3 | GO:0050886 | |
| GeneOntologyBiologicalProcess | nephron epithelium development | 3.29e-03 | 128 | 48 | 3 | GO:0072009 | |
| GeneOntologyBiologicalProcess | cellular response to growth factor stimulus | 3.32e-03 | 850 | 48 | 7 | GO:0071363 | |
| GeneOntologyCellularComponent | transcription regulator complex | DACH1 SKOR1 NCOR1 POU4F1 DR1 CHD3 CDX2 SIX4 SPEN TBL1XR1 NKX2-1 SMAD4 TBL1X | 5.58e-10 | 596 | 48 | 13 | GO:0005667 |
| GeneOntologyCellularComponent | transcription repressor complex | 4.65e-08 | 87 | 48 | 6 | GO:0017053 | |
| GeneOntologyCellularComponent | chromatin | SOX1 HOXA13 NCOR1 POU4F1 DR1 CHD3 CDX2 MAU2 SIX4 GMEB2 NKX2-1 ZMIZ2 FOXD1 SMAD4 | 3.66e-06 | 1480 | 48 | 14 | GO:0000785 |
| GeneOntologyCellularComponent | histone deacetylase complex | 4.32e-05 | 85 | 48 | 4 | GO:0000118 | |
| GeneOntologyCellularComponent | mitotic spindle | 1.16e-03 | 201 | 48 | 4 | GO:0072686 | |
| Domain | - | 8.25e-05 | 283 | 48 | 6 | 1.10.10.60 | |
| Domain | Homeobox_CS | 1.12e-04 | 186 | 48 | 5 | IPR017970 | |
| Domain | Ski_Sno | 1.35e-04 | 7 | 48 | 2 | PF02437 | |
| Domain | - | 1.35e-04 | 7 | 48 | 2 | 3.10.260.20 | |
| Domain | Transform_Ski | 1.35e-04 | 7 | 48 | 2 | IPR003380 | |
| Domain | Homeodomain-like | 1.97e-04 | 332 | 48 | 6 | IPR009057 | |
| Domain | LisH | 2.30e-04 | 9 | 48 | 2 | PF08513 | |
| Domain | Homeobox | 3.26e-04 | 234 | 48 | 5 | PF00046 | |
| Domain | HOMEOBOX_1 | 3.40e-04 | 236 | 48 | 5 | PS00027 | |
| Domain | HOX | 3.46e-04 | 237 | 48 | 5 | SM00389 | |
| Domain | DNA-bd_dom_put | 3.51e-04 | 11 | 48 | 2 | IPR009061 | |
| Domain | Homeobox_dom | 3.60e-04 | 239 | 48 | 5 | IPR001356 | |
| Domain | HOMEOBOX_2 | 3.60e-04 | 239 | 48 | 5 | PS50071 | |
| Domain | SAND_dom-like | 4.20e-04 | 12 | 48 | 2 | IPR010919 | |
| Domain | - | 4.20e-04 | 12 | 48 | 2 | 3.10.390.10 | |
| Domain | PI3_4_KINASE_1 | 9.64e-04 | 18 | 48 | 2 | PS00915 | |
| Domain | PI3_4_KINASE_2 | 9.64e-04 | 18 | 48 | 2 | PS00916 | |
| Domain | PI3/4_kinase_cat_dom | 9.64e-04 | 18 | 48 | 2 | IPR000403 | |
| Domain | PI3_PI4_kinase | 9.64e-04 | 18 | 48 | 2 | PF00454 | |
| Domain | PI3_4_KINASE_3 | 9.64e-04 | 18 | 48 | 2 | PS50290 | |
| Domain | zf-C2H2_jaz | 1.45e-03 | 22 | 48 | 2 | PF12171 | |
| Domain | Znf_C2H2_jaz | 1.45e-03 | 22 | 48 | 2 | IPR022755 | |
| Domain | LisH | 2.34e-03 | 28 | 48 | 2 | IPR006594 | |
| Domain | LisH | 2.34e-03 | 28 | 48 | 2 | SM00667 | |
| Domain | LISH | 2.34e-03 | 28 | 48 | 2 | PS50896 | |
| Domain | KH_1 | 4.29e-03 | 38 | 48 | 2 | PF00013 | |
| Domain | - | 4.51e-03 | 39 | 48 | 2 | 3.30.1370.10 | |
| Domain | KH | 4.74e-03 | 40 | 48 | 2 | SM00322 | |
| Domain | KH_dom | 4.74e-03 | 40 | 48 | 2 | IPR004087 | |
| Domain | KH_TYPE_1 | 5.22e-03 | 42 | 48 | 2 | PS50084 | |
| Domain | KH_dom_type_1 | 5.71e-03 | 44 | 48 | 2 | IPR004088 | |
| Domain | - | 8.81e-03 | 55 | 48 | 2 | 1.10.30.10 | |
| Pathway | REACTOME_LOSS_OF_MECP2_BINDING_ABILITY_TO_THE_NCOR_SMRT_COMPLEX | 4.06e-07 | 7 | 33 | 3 | M27899 | |
| Pathway | REACTOME_LOSS_OF_FUNCTION_OF_MECP2_IN_RETT_SYNDROME | 3.29e-06 | 13 | 33 | 3 | M29766 | |
| Pathway | REACTOME_ADIPOGENESIS | 5.26e-06 | 110 | 33 | 5 | M48259 | |
| Pathway | REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY | 3.68e-05 | 28 | 33 | 3 | M6177 | |
| Pathway | REACTOME_REGULATION_OF_MECP2_EXPRESSION_AND_ACTIVITY | 5.53e-05 | 32 | 33 | 3 | M27900 | |
| Pathway | REACTOME_HDACS_DEACETYLATE_HISTONES | 6.54e-05 | 94 | 33 | 4 | M27230 | |
| Pathway | REACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX | 8.60e-05 | 37 | 33 | 3 | M29790 | |
| Pathway | REACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING | 1.77e-04 | 47 | 33 | 3 | M29777 | |
| Pathway | WP_RETT_SYNDROME | 1.88e-04 | 48 | 33 | 3 | M39759 | |
| Pathway | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | 1.88e-04 | 48 | 33 | 3 | M611 | |
| Pathway | REACTOME_HEME_SIGNALING | 2.00e-04 | 49 | 33 | 3 | M41832 | |
| Pathway | REACTOME_HDACS_DEACETYLATE_HISTONES | 2.82e-04 | 55 | 33 | 3 | MM14932 | |
| Pathway | REACTOME_TRANSCRIPTIONAL_ACTIVATION_OF_MITOCHONDRIAL_BIOGENESIS | 2.82e-04 | 55 | 33 | 3 | M27145 | |
| Pathway | REACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER | 3.30e-04 | 58 | 33 | 3 | M29616 | |
| Pathway | WP_ENDODERM_DIFFERENTIATION | 3.31e-04 | 143 | 33 | 4 | M39591 | |
| Pathway | WP_PREIMPLANTATION_EMBRYO | 3.47e-04 | 59 | 33 | 3 | M39579 | |
| Pathway | REACTOME_CYTOPROTECTION_BY_HMOX1 | 3.65e-04 | 60 | 33 | 3 | M41830 | |
| Pathway | REACTOME_CHROMATIN_MODIFYING_ENZYMES | 3.93e-04 | 272 | 33 | 5 | M29619 | |
| Pathway | REACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING | 4.08e-04 | 13 | 33 | 2 | MM15622 | |
| Pathway | REACTOME_TRANSCRIPTIONAL_REGULATION_BY_MECP2 | 4.22e-04 | 63 | 33 | 3 | M27862 | |
| Pathway | PID_ERA_GENOMIC_PATHWAY | 4.42e-04 | 64 | 33 | 3 | M200 | |
| Pathway | REACTOME_CIRCADIAN_CLOCK | 5.75e-04 | 70 | 33 | 3 | M938 | |
| Pathway | REACTOME_SIGNALING_BY_NOTCH1 | 6.77e-04 | 74 | 33 | 3 | M616 | |
| Pathway | REACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA | 7.94e-04 | 18 | 33 | 2 | MM15034 | |
| Pathway | REACTOME_RORA_ACTIVATES_GENE_EXPRESSION | 7.94e-04 | 18 | 33 | 2 | M26942 | |
| Pathway | WP_DELTANOTCH_SIGNALING_PATHWAY | 9.13e-04 | 82 | 33 | 3 | MM15922 | |
| Pathway | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | 9.79e-04 | 84 | 33 | 3 | M1008 | |
| Pathway | REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY | 1.30e-03 | 23 | 33 | 2 | MM14954 | |
| Pathway | REACTOME_MITOCHONDRIAL_BIOGENESIS | 1.44e-03 | 96 | 33 | 3 | M26973 | |
| Pathway | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_GENE_EXPRESSION | 1.80e-03 | 27 | 33 | 2 | M26943 | |
| Pathway | WP_GLYCEROPHOSPHOLIPID_BIOSYNTHETIC_PATHWAY | 2.22e-03 | 30 | 33 | 2 | M39592 | |
| Pathway | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | 2.37e-03 | 31 | 33 | 2 | M669 | |
| Pathway | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_BROWN_AND_BEIGE_ADIPOCYTE_DIFFERENTIATION | 2.37e-03 | 31 | 33 | 2 | M48258 | |
| Pathway | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_PLURIPOTENT_STEM_CELLS | 2.37e-03 | 31 | 33 | 2 | M27393 | |
| Pathway | REACTOME_RUNX2_REGULATES_BONE_DEVELOPMENT | 2.37e-03 | 31 | 33 | 2 | M27805 | |
| Pathway | REACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA | 2.60e-03 | 118 | 33 | 3 | M27316 | |
| Pathway | WP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES | 2.60e-03 | 118 | 33 | 3 | M39852 | |
| Pubmed | DACH1 CCAR1 PRR12 NCOR1 ZFR IRF2BPL CHD3 SIX4 ARID3A GMEB2 PUM1 SPEN TBL1XR1 PRPF40A GLI2 EMSY ZMIZ2 MAZ TBL1X | 1.51e-14 | 1429 | 48 | 19 | 35140242 | |
| Pubmed | 2.60e-13 | 83 | 48 | 8 | 28794006 | ||
| Pubmed | Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. | DACH1 NCOR1 ZFR CDX2 SIX4 ARID3A PUM1 SPEN TBL1XR1 EMSY FOXD1 SMAD4 NOVA1 NOVA2 TBL1X | 3.41e-13 | 857 | 48 | 15 | 25609649 |
| Pubmed | The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers. | DACH1 CCAR1 HOXA13 ZNF384 NCOR1 ZFR CHD3 SERBP1 PUM1 SPEN MBNL2 PRPF40A EMSY MAZ | 2.52e-11 | 954 | 48 | 14 | 36373674 |
| Pubmed | SOX1 CCAR1 NCOR1 ZFR DR1 CHD3 CDX2 SIX4 ARID3A MBNL2 NKX2-1 ZMIZ2 SMAD4 | 4.76e-11 | 808 | 48 | 13 | 20412781 | |
| Pubmed | H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids. | CCAR1 PRR12 NCOR1 ZFR DR1 CHD3 MAU2 SIX4 SPEN TBL1XR1 PRPF40A EMSY MAZ SMAD4 TBL1X | 1.15e-10 | 1294 | 48 | 15 | 30804502 |
| Pubmed | DACH1 CCAR1 PRR12 HOXA13 ZNF384 NCOR1 ZFR CHD3 ARID3A GMEB2 SPEN TBL1XR1 EMSY ZMIZ2 | 1.69e-10 | 1103 | 48 | 14 | 34189442 | |
| Pubmed | A census of human transcription factors: function, expression and evolution. | SOX1 SKOR1 HOXA13 ZNF384 POU4F1 DR1 CDX2 SIX4 GMEB2 NKX2-1 GLI2 MAZ SMAD4 | 1.99e-10 | 908 | 48 | 13 | 19274049 |
| Pubmed | Interaction network of human early embryonic transcription factors. | 1.16e-09 | 351 | 48 | 9 | 38297188 | |
| Pubmed | TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation. | 2.18e-08 | 220 | 48 | 7 | 35785414 | |
| Pubmed | 2.46e-08 | 5 | 48 | 3 | 18202150 | ||
| Pubmed | 2.46e-08 | 5 | 48 | 3 | 18326024 | ||
| Pubmed | 4.92e-08 | 6 | 48 | 3 | 28348241 | ||
| Pubmed | Impact of cytosine methylation on DNA binding specificities of human transcription factors. | 5.12e-08 | 544 | 48 | 9 | 28473536 | |
| Pubmed | A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal. | 5.24e-08 | 146 | 48 | 6 | 23892456 | |
| Pubmed | Zbtb7c is a molecular 'off' and 'on' switch of Mmp gene transcription. | 8.60e-08 | 7 | 48 | 3 | 27646874 | |
| Pubmed | 8.60e-08 | 7 | 48 | 3 | 15695367 | ||
| Pubmed | Proteome-scale mapping of binding sites in the unstructured regions of the human proteome. | 1.25e-07 | 430 | 48 | 8 | 35044719 | |
| Pubmed | The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. | 1.26e-07 | 807 | 48 | 10 | 22681889 | |
| Pubmed | Requirement of Smad4 from Ocular Surface Ectoderm for Retinal Development. | 1.37e-07 | 8 | 48 | 3 | 27494603 | |
| Pubmed | DACH1 inhibits transforming growth factor-beta signaling through binding Smad4. | 1.37e-07 | 8 | 48 | 3 | 14525983 | |
| Pubmed | Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor. | 1.37e-07 | 8 | 48 | 3 | 23770565 | |
| Pubmed | 1.37e-07 | 8 | 48 | 3 | 16127449 | ||
| Pubmed | 2.00e-07 | 183 | 48 | 6 | 36129980 | ||
| Pubmed | Reading and function of a histone code involved in targeting corepressor complexes for repression. | 2.06e-07 | 9 | 48 | 3 | 15601853 | |
| Pubmed | 2.94e-07 | 10 | 48 | 3 | 19032343 | ||
| Pubmed | 2.94e-07 | 10 | 48 | 3 | 14980219 | ||
| Pubmed | 2.94e-07 | 10 | 48 | 3 | 11931768 | ||
| Pubmed | N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso. | 6.99e-07 | 13 | 48 | 3 | 14527417 | |
| Pubmed | 8.88e-07 | 14 | 48 | 3 | 27880911 | ||
| Pubmed | 1.11e-06 | 15 | 48 | 3 | 17242407 | ||
| Pubmed | 1.11e-06 | 15 | 48 | 3 | 12628926 | ||
| Pubmed | 1.65e-06 | 17 | 48 | 3 | 28778798 | ||
| Pubmed | 1.70e-06 | 608 | 48 | 8 | 16713569 | ||
| Pubmed | The in vivo Interaction Landscape of Histones H3.1 and H3.3. | 1.70e-06 | 608 | 48 | 8 | 36089195 | |
| Pubmed | 1.85e-06 | 268 | 48 | 6 | 33640491 | ||
| Pubmed | 1.87e-06 | 2 | 48 | 2 | 9789075 | ||
| Pubmed | 1.87e-06 | 2 | 48 | 2 | 35848993 | ||
| Pubmed | 1.87e-06 | 2 | 48 | 2 | 37909960 | ||
| Pubmed | 1.87e-06 | 2 | 48 | 2 | 20518411 | ||
| Pubmed | Crystal structures of Nova-1 and Nova-2 K-homology RNA-binding domains. | 1.87e-06 | 2 | 48 | 2 | 10368286 | |
| Pubmed | TBL1X: At the crossroads of transcriptional and posttranscriptional regulation. | 1.87e-06 | 2 | 48 | 2 | 36206873 | |
| Pubmed | Integrative modeling defines the Nova splicing-regulatory network and its combinatorial controls. | 1.87e-06 | 2 | 48 | 2 | 20558669 | |
| Pubmed | SUMOylation of TBL1 and TBLR1 promotes androgen-independent prostate cancer cell growth. | 1.87e-06 | 2 | 48 | 2 | 27129164 | |
| Pubmed | 1.87e-06 | 2 | 48 | 2 | 17065982 | ||
| Pubmed | 1.87e-06 | 2 | 48 | 2 | 14615540 | ||
| Pubmed | HITS-CLIP yields genome-wide insights into brain alternative RNA processing. | 1.87e-06 | 2 | 48 | 2 | 18978773 | |
| Pubmed | 1.87e-06 | 2 | 48 | 2 | 12897056 | ||
| Pubmed | The tetranucleotide UCAY directs the specific recognition of RNA by the Nova K-homology 3 domain. | 1.87e-06 | 2 | 48 | 2 | 10811881 | |
| Pubmed | Nova regulates brain-specific splicing to shape the synapse. | 1.87e-06 | 2 | 48 | 2 | 16041372 | |
| Pubmed | 2.07e-06 | 847 | 48 | 9 | 35850772 | ||
| Pubmed | TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas. | 2.20e-06 | 152 | 48 | 5 | 28192407 | |
| Pubmed | 2.35e-06 | 19 | 48 | 3 | 29166577 | ||
| Pubmed | Gene expression and cell identity controlled by anaphase-promoting complex. | 2.44e-06 | 68 | 48 | 4 | 32076268 | |
| Pubmed | Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells. | 2.54e-06 | 283 | 48 | 6 | 30585729 | |
| Pubmed | An atlas of combinatorial transcriptional regulation in mouse and man. | 2.75e-06 | 877 | 48 | 9 | 20211142 | |
| Pubmed | 2.77e-06 | 20 | 48 | 3 | 27773593 | ||
| Pubmed | The functional interactome landscape of the human histone deacetylase family. | 2.86e-06 | 289 | 48 | 6 | 23752268 | |
| Pubmed | 3.22e-06 | 21 | 48 | 3 | 32169553 | ||
| Pubmed | Comparative mapping of human Chromosome 14q11.2-q13 genes with mouse homologous gene regions. | 5.59e-06 | 3 | 48 | 2 | 11063256 | |
| Pubmed | Simultaneous expression of COX-2 and mPGES-1 in mouse gastrointestinal hamartomas. | 5.59e-06 | 3 | 48 | 2 | 14760387 | |
| Pubmed | 5.59e-06 | 3 | 48 | 2 | 27389559 | ||
| Pubmed | 5.59e-06 | 3 | 48 | 2 | 19266212 | ||
| Pubmed | De novo non-synonymous TBL1XR1 mutation alters Wnt signaling activity. | 5.59e-06 | 3 | 48 | 2 | 28588275 | |
| Pubmed | 5.59e-06 | 3 | 48 | 2 | 12505151 | ||
| Pubmed | Ocular albinism with infertility and late-onset sensorineural hearing loss. | 5.59e-06 | 3 | 48 | 2 | 30160833 | |
| Pubmed | 6.70e-06 | 191 | 48 | 5 | 24146773 | ||
| Pubmed | 8.79e-06 | 29 | 48 | 3 | 27320915 | ||
| Pubmed | 8.87e-06 | 1014 | 48 | 9 | 32416067 | ||
| Pubmed | Control of developmentally primed erythroid genes by combinatorial co-repressor actions. | 9.76e-06 | 30 | 48 | 3 | 26593974 | |
| Pubmed | 9.88e-06 | 549 | 48 | 7 | 38280479 | ||
| Pubmed | Large-scale characterization of HeLa cell nuclear phosphoproteins. | 9.97e-06 | 774 | 48 | 8 | 15302935 | |
| Pubmed | The alternative splicing factor Nova2 regulates vascular development and lumen formation. | 1.12e-05 | 4 | 48 | 2 | 26446569 | |
| Pubmed | 1.12e-05 | 4 | 48 | 2 | 26469326 | ||
| Pubmed | 1.12e-05 | 4 | 48 | 2 | 18193033 | ||
| Pubmed | 1.12e-05 | 4 | 48 | 2 | 18374649 | ||
| Pubmed | 1.12e-05 | 4 | 48 | 2 | 22495359 | ||
| Pubmed | Degree of Tissue Differentiation Dictates Susceptibility to BRAF-Driven Colorectal Cancer. | 1.86e-05 | 5 | 48 | 2 | 29281831 | |
| Pubmed | 1.86e-05 | 5 | 48 | 2 | 19221030 | ||
| Pubmed | The novel PIAS-like protein hZimp10 enhances Smad transcriptional activity. | 1.86e-05 | 5 | 48 | 2 | 16777850 | |
| Pubmed | 1.86e-05 | 5 | 48 | 2 | 12161428 | ||
| Pubmed | 1.86e-05 | 5 | 48 | 2 | 28152507 | ||
| Pubmed | 1.86e-05 | 5 | 48 | 2 | 21459324 | ||
| Pubmed | A screen for MeCP2-TBL1 interaction inhibitors using a luminescence-based assay. | 1.86e-05 | 5 | 48 | 2 | 36890145 | |
| Pubmed | 1.86e-05 | 5 | 48 | 2 | 19004857 | ||
| Pubmed | SENP2 regulates MMP13 expression in a bladder cancer cell line through SUMOylation of TBL1/TBLR1. | 1.86e-05 | 5 | 48 | 2 | 26369384 | |
| Pubmed | A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness. | 1.86e-05 | 5 | 48 | 2 | 10809664 | |
| Pubmed | 1.91e-05 | 114 | 48 | 4 | 31553912 | ||
| Pubmed | Transcription factor protein interactomes reveal genetic determinants in heart disease. | 2.12e-05 | 411 | 48 | 6 | 35182466 | |
| Pubmed | 2.56e-05 | 425 | 48 | 6 | 24999758 | ||
| Pubmed | 2.79e-05 | 6 | 48 | 2 | 27585885 | ||
| Pubmed | 2.79e-05 | 6 | 48 | 2 | 10829067 | ||
| Pubmed | 2.79e-05 | 6 | 48 | 2 | 32198202 | ||
| Pubmed | Molecular embryology of the lung: then, now, and in the future. | 2.79e-05 | 6 | 48 | 2 | 10330024 | |
| Pubmed | An alternative splicing program promotes adipose tissue thermogenesis. | 2.79e-05 | 6 | 48 | 2 | 27635635 | |
| Pubmed | 2.79e-05 | 6 | 48 | 2 | 12764135 | ||
| Pubmed | 2.79e-05 | 6 | 48 | 2 | 25407941 | ||
| Pubmed | 3.10e-05 | 1497 | 48 | 10 | 31527615 | ||
| Pubmed | Identification of proximal SUMO-dependent interactors using SUMO-ID. | 3.26e-05 | 444 | 48 | 6 | 34795231 | |
| Pubmed | Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes. | 3.36e-05 | 45 | 48 | 3 | 21258344 | |
| Interaction | SP7 interactions | CCAR1 PRR12 NCOR1 ZFR CHD3 SIX4 ARID3A TBL1XR1 PRPF40A ZMIZ2 TBL1X | 1.06e-10 | 304 | 48 | 11 | int:SP7 |
| Interaction | GATA3 interactions | 5.16e-10 | 187 | 48 | 9 | int:GATA3 | |
| Interaction | NFIX interactions | 2.85e-09 | 227 | 48 | 9 | int:NFIX | |
| Interaction | TEAD1 interactions | 8.08e-09 | 176 | 48 | 8 | int:TEAD1 | |
| Interaction | TBXT interactions | 1.06e-08 | 116 | 48 | 7 | int:TBXT | |
| Interaction | HNF4A interactions | 1.52e-08 | 275 | 48 | 9 | int:HNF4A | |
| Interaction | GUSBP5 interactions | 2.35e-08 | 75 | 48 | 6 | int:GUSBP5 | |
| Interaction | NFIC interactions | 3.21e-08 | 210 | 48 | 8 | int:NFIC | |
| Interaction | AR interactions | CCAR1 PRR12 HOXA13 NCOR1 ZFR IRF2BPL CHD3 TBL1XR1 PRPF40A GLI2 EMSY ZMIZ2 SMAD4 TBL1X | 4.50e-08 | 992 | 48 | 14 | int:AR |
| Interaction | SMC5 interactions | DACH1 CCAR1 HOXA13 ZNF384 NCOR1 ZFR CHD3 SERBP1 PUM1 SPEN MBNL2 PRPF40A EMSY MAZ | 4.97e-08 | 1000 | 48 | 14 | int:SMC5 |
| Interaction | CEBPA interactions | DACH1 CCAR1 PRR12 HOXA13 ZNF384 NCOR1 ZFR CHD3 ARID3A GMEB2 SPEN TBL1XR1 EMSY ZMIZ2 SMAD4 | 1.06e-07 | 1245 | 48 | 15 | int:CEBPA |
| Interaction | PAX6 interactions | 1.75e-07 | 366 | 48 | 9 | int:PAX6 | |
| Interaction | TLE3 interactions | 2.20e-07 | 376 | 48 | 9 | int:TLE3 | |
| Interaction | ALG13 interactions | 2.44e-07 | 183 | 48 | 7 | int:ALG13 | |
| Interaction | FHL2 interactions | 3.40e-07 | 396 | 48 | 9 | int:FHL2 | |
| Interaction | FOXL1 interactions | 3.88e-07 | 196 | 48 | 7 | int:FOXL1 | |
| Interaction | CTBP1 interactions | 4.19e-07 | 406 | 48 | 9 | int:CTBP1 | |
| Interaction | GATA2 interactions | 4.30e-07 | 199 | 48 | 7 | int:GATA2 | |
| Interaction | PAX7 interactions | 4.77e-07 | 124 | 48 | 6 | int:PAX7 | |
| Interaction | FEV interactions | 4.92e-07 | 203 | 48 | 7 | int:FEV | |
| Interaction | TERF2IP interactions | DACH1 CCAR1 NCOR1 CHD3 ARID3A GMEB2 SPEN TBL1XR1 PRPF40A EMSY | 5.62e-07 | 552 | 48 | 10 | int:TERF2IP |
| Interaction | SMG7 interactions | 7.85e-07 | 319 | 48 | 8 | int:SMG7 | |
| Interaction | MIER1 interactions | 1.30e-06 | 80 | 48 | 5 | int:MIER1 | |
| Interaction | SNRNP40 interactions | 2.05e-06 | 637 | 48 | 10 | int:SNRNP40 | |
| Interaction | SOX5 interactions | 2.28e-06 | 162 | 48 | 6 | int:SOX5 | |
| Interaction | UBE2I interactions | DACH1 NCOR1 CHD3 GMEB2 TBL1XR1 NKX2-1 PRPF40A GLI2 SMAD4 TBL1X | 2.60e-06 | 654 | 48 | 10 | int:UBE2I |
| Interaction | EGR2 interactions | 3.12e-06 | 171 | 48 | 6 | int:EGR2 | |
| Interaction | SOX2 interactions | SOX1 DACH1 PRR12 ZNF384 NCOR1 ZFR CHD3 SERBP1 SIX4 ARID3A SPEN TBL1XR1 ZMIZ2 TBL1X | 3.51e-06 | 1422 | 48 | 14 | int:SOX2 |
| Interaction | TLX1 interactions | 3.57e-06 | 175 | 48 | 6 | int:TLX1 | |
| Interaction | SSRP1 interactions | CCAR1 ZNF384 NCOR1 ZFR CHD3 MAU2 TBL1XR1 NKX2-1 PRPF40A TBL1X | 3.92e-06 | 685 | 48 | 10 | int:SSRP1 |
| Interaction | USP44 interactions | 4.29e-06 | 46 | 48 | 4 | int:USP44 | |
| Interaction | KLF15 interactions | 5.28e-06 | 290 | 48 | 7 | int:KLF15 | |
| Interaction | NFIA interactions | 5.39e-06 | 188 | 48 | 6 | int:NFIA | |
| Interaction | TLX3 interactions | 5.40e-06 | 291 | 48 | 7 | int:TLX3 | |
| Interaction | HNF1B interactions | 5.73e-06 | 190 | 48 | 6 | int:HNF1B | |
| Interaction | KLF5 interactions | 6.65e-06 | 195 | 48 | 6 | int:KLF5 | |
| Interaction | EWSR1 interactions | DACH1 PRR12 NCOR1 ZFR POU4F1 CHD3 SERBP1 GMEB2 PRPF40A MAZ SMAD4 | 6.99e-06 | 906 | 48 | 11 | int:EWSR1 |
| Interaction | HDAC1 interactions | DACH1 SKOR1 NCOR1 CHD3 SPEN TBL1XR1 NKX2-1 GLI2 EMSY ZMIZ2 SMAD4 TBL1X | 7.93e-06 | 1108 | 48 | 12 | int:HDAC1 |
| Interaction | XRCC6 interactions | DACH1 NCOR1 ZFR CHD3 CDX2 SERBP1 SPEN NKX2-1 PRPF40A EMSY SMAD4 | 8.77e-06 | 928 | 48 | 11 | int:XRCC6 |
| Interaction | TPRX2 interactions | 9.50e-06 | 56 | 48 | 4 | int:TPRX2 | |
| Interaction | MYB interactions | 1.58e-05 | 133 | 48 | 5 | int:MYB | |
| Interaction | NANOG interactions | 1.62e-05 | 481 | 48 | 8 | int:NANOG | |
| Interaction | SMARCD1 interactions | 1.76e-05 | 349 | 48 | 7 | int:SMARCD1 | |
| Interaction | PIAS1 interactions | 1.89e-05 | 353 | 48 | 7 | int:PIAS1 | |
| Interaction | NFIB interactions | 2.17e-05 | 142 | 48 | 5 | int:NFIB | |
| Interaction | TDG interactions | 2.19e-05 | 69 | 48 | 4 | int:TDG | |
| Interaction | MEN1 interactions | PRR12 ZNF384 NCOR1 ZFR IRF2BPL CHD3 PUM1 SPEN PRPF40A EMSY SMAD4 | 2.31e-05 | 1029 | 48 | 11 | int:MEN1 |
| Interaction | ATXN1 interactions | CCAR1 NCOR1 ZFR IRF2BPL SERBP1 GMEB2 PUM1 SPEN TBL1XR1 ZNF804A PRPF40A | 2.52e-05 | 1039 | 48 | 11 | int:ATXN1 |
| Interaction | APEX1 interactions | DACH1 CCAR1 ZNF384 DR1 MAU2 ARID3A GMEB2 PIK3CB SCAMP1 EMSY MAZ SMAD4 | 3.13e-05 | 1271 | 48 | 12 | int:APEX1 |
| Interaction | SOX6 interactions | 3.52e-05 | 157 | 48 | 5 | int:SOX6 | |
| Interaction | FOXE1 interactions | 4.12e-05 | 81 | 48 | 4 | int:FOXE1 | |
| Interaction | DGKG interactions | 4.44e-05 | 29 | 48 | 3 | int:DGKG | |
| Interaction | PIAS4 interactions | 5.59e-05 | 173 | 48 | 5 | int:PIAS4 | |
| Interaction | NUP35 interactions | 6.07e-05 | 424 | 48 | 7 | int:NUP35 | |
| Interaction | NKX2-1 interactions | 6.74e-05 | 180 | 48 | 5 | int:NKX2-1 | |
| Interaction | CREBBP interactions | 7.68e-05 | 599 | 48 | 8 | int:CREBBP | |
| Interaction | SOX17 interactions | 7.69e-05 | 95 | 48 | 4 | int:SOX17 | |
| Interaction | PIAS3 interactions | 7.69e-05 | 95 | 48 | 4 | int:PIAS3 | |
| Interaction | PRPF40A interactions | 8.34e-05 | 446 | 48 | 7 | int:PRPF40A | |
| Interaction | TBL1XR1 interactions | 9.15e-05 | 192 | 48 | 5 | int:TBL1XR1 | |
| Interaction | MYOD1 interactions | 9.61e-05 | 194 | 48 | 5 | int:MYOD1 | |
| Interaction | SMARCA4 interactions | 1.04e-04 | 462 | 48 | 7 | int:SMARCA4 | |
| Interaction | CEBPB interactions | CCAR1 ZNF384 NCOR1 ZFR IRF2BPL DR1 SERBP1 ARID3A TBL1XR1 NKX2-1 PRPF40A SMAD4 | 1.07e-04 | 1443 | 48 | 12 | int:CEBPB |
| Interaction | RBM25 interactions | 1.13e-04 | 323 | 48 | 6 | int:RBM25 | |
| Interaction | TBL1Y interactions | 1.18e-04 | 40 | 48 | 3 | int:TBL1Y | |
| Interaction | FBL interactions | 1.20e-04 | 639 | 48 | 8 | int:FBL | |
| Interaction | EN1 interactions | 1.36e-04 | 110 | 48 | 4 | int:EN1 | |
| Interaction | IRF2BP2 interactions | 1.36e-04 | 110 | 48 | 4 | int:IRF2BP2 | |
| Interaction | NUP50 interactions | 1.51e-04 | 341 | 48 | 6 | int:NUP50 | |
| Interaction | HDAC2 interactions | 1.76e-04 | 865 | 48 | 9 | int:HDAC2 | |
| Interaction | SMARCC2 interactions | 1.83e-04 | 353 | 48 | 6 | int:SMARCC2 | |
| Interaction | ERG interactions | 1.84e-04 | 223 | 48 | 5 | int:ERG | |
| Interaction | KLF3 interactions | 2.04e-04 | 228 | 48 | 5 | int:KLF3 | |
| Interaction | NCOR1 interactions | 2.12e-04 | 363 | 48 | 6 | int:NCOR1 | |
| Interaction | PAX9 interactions | 2.58e-04 | 130 | 48 | 4 | int:PAX9 | |
| Interaction | FMR1 interactions | 2.59e-04 | 536 | 48 | 7 | int:FMR1 | |
| Interaction | FOXB1 interactions | 2.98e-04 | 135 | 48 | 4 | int:FOXB1 | |
| Interaction | CREB1 interactions | 3.36e-04 | 254 | 48 | 5 | int:CREB1 | |
| Interaction | RBPJ interactions | 3.36e-04 | 254 | 48 | 5 | int:RBPJ | |
| Interaction | TLX2 interactions | 3.61e-04 | 142 | 48 | 4 | int:TLX2 | |
| Interaction | GPS2 interactions | 3.81e-04 | 144 | 48 | 4 | int:GPS2 | |
| Interaction | VSX1 interactions | 5.22e-04 | 66 | 48 | 3 | int:VSX1 | |
| Interaction | CCT8L2 interactions | 5.28e-04 | 157 | 48 | 4 | int:CCT8L2 | |
| Interaction | HSF1 interactions | 5.58e-04 | 609 | 48 | 7 | int:HSF1 | |
| Interaction | SKI interactions | 5.67e-04 | 160 | 48 | 4 | int:SKI | |
| Interaction | CORO2A interactions | 5.70e-04 | 68 | 48 | 3 | int:CORO2A | |
| Interaction | GCM1 interactions | 5.70e-04 | 68 | 48 | 3 | int:GCM1 | |
| Interaction | ETV4 interactions | 5.95e-04 | 69 | 48 | 3 | int:ETV4 | |
| Interaction | CELF1 interactions | 5.96e-04 | 288 | 48 | 5 | int:CELF1 | |
| Interaction | HNRNPUL2 interactions | 6.25e-04 | 291 | 48 | 5 | int:HNRNPUL2 | |
| Interaction | LHX4 interactions | 6.51e-04 | 166 | 48 | 4 | int:LHX4 | |
| Interaction | CELA2A interactions | 6.53e-04 | 16 | 48 | 2 | int:CELA2A | |
| Interaction | EYA3 interactions | 7.02e-04 | 73 | 48 | 3 | int:EYA3 | |
| Interaction | HNRNPC interactions | 7.08e-04 | 634 | 48 | 7 | int:HNRNPC | |
| Interaction | EIF4ENIF1 interactions | 7.17e-04 | 300 | 48 | 5 | int:EIF4ENIF1 | |
| Interaction | GATA1 interactions | 7.28e-04 | 171 | 48 | 4 | int:GATA1 | |
| Interaction | NOVA2 interactions | 7.38e-04 | 17 | 48 | 2 | int:NOVA2 | |
| Interaction | FUBP1 interactions | 8.19e-04 | 309 | 48 | 5 | int:FUBP1 | |
| Interaction | MKX interactions | 8.29e-04 | 18 | 48 | 2 | int:MKX | |
| Interaction | JUN interactions | 8.34e-04 | 470 | 48 | 6 | int:JUN | |
| Cytoband | Xp22.3 | 2.67e-04 | 23 | 48 | 2 | Xp22.3 | |
| CoexpressionAtlas | DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_1000 | DACH1 KLHL11 RANBP6 HOXA13 SIX4 ATL2 TBL1XR1 ZNF804A NOVA1 TBL1X | 9.66e-06 | 818 | 47 | 10 | DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_1000 |
| CoexpressionAtlas | DevelopingGonad_e12.5_testes_emap-29069_k-means-cluster#1_top-relative-expression-ranked_1000 | 1.76e-05 | 524 | 47 | 8 | gudmap_developingGonad_e12.5_testes_k1_1000 | |
| CoexpressionAtlas | DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_1000 | 5.83e-05 | 806 | 47 | 9 | DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_1000 | |
| CoexpressionAtlas | DevelopingGonad_e11.5_testes_emap-3226_k-means-cluster#2_top-relative-expression-ranked_1000 | 7.30e-05 | 197 | 47 | 5 | gudmap_developingGonad_e11.5_testes_k2_1000 | |
| CoexpressionAtlas | DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000 | 7.72e-05 | 836 | 47 | 9 | gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000 | |
| CoexpressionAtlas | DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#5_top-relative-expression-ranked_1000 | 9.69e-05 | 492 | 47 | 7 | gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k5 | |
| CoexpressionAtlas | DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#2_top-relative-expression-ranked_500 | 2.07e-04 | 132 | 47 | 4 | DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k2_500 | |
| CoexpressionAtlas | DevelopingGonad_e11.5_testes_emap-3226_k-means-cluster#3_top-relative-expression-ranked_500 | 2.88e-04 | 144 | 47 | 4 | gudmap_developingGonad_e11.5_testes_k3_500 | |
| CoexpressionAtlas | DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#2_top-relative-expression-ranked_1000 | 3.37e-04 | 150 | 47 | 4 | gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_1000_k2 | |
| CoexpressionAtlas | DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_1000 | 3.67e-04 | 811 | 47 | 8 | gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000 | |
| CoexpressionAtlas | kidney_P2_CapMes_Crym_k-means-cluster#1_top-relative-expression-ranked_200 | 3.68e-04 | 13 | 47 | 2 | gudmap_kidney_P2_CapMes_Crym_k1_200 | |
| CoexpressionAtlas | DevelopingGonad_e12.5_testes_emap-29069_top-relative-expression-ranked_1000 | 3.92e-04 | 819 | 47 | 8 | gudmap_developingGonad_e12.5_testes_1000 | |
| CoexpressionAtlas | kidney_P3_CapMes_Crym_k-means-cluster#3_top-relative-expression-ranked_200 | 4.29e-04 | 14 | 47 | 2 | gudmap_kidney_P3_CapMes_Crym_k3_200 | |
| CoexpressionAtlas | DevelopingGonad_e11.5_testes_emap-3226_top-relative-expression-ranked_1000 | 4.75e-04 | 843 | 47 | 8 | gudmap_developingGonad_e11.5_testes_1000 | |
| Computational | Genes in the cancer module 98. | 2.29e-04 | 393 | 35 | 7 | MODULE_98 | |
| Drug | Primaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A | 2.69e-06 | 188 | 48 | 6 | 4845_DN | |
| Drug | Ampyrone [83-07-8]; Down 200; 19.6uM; PC3; HT_HG-U133A | 2.86e-06 | 190 | 48 | 6 | 4507_DN | |
| Drug | Sulfamethazine sodium salt [1981-58-4]; Down 200; 13.4uM; PC3; HT_HG-U133A | 2.86e-06 | 190 | 48 | 6 | 4322_DN | |
| Drug | Piperacillin sodium salt [59703-84-3]; Down 200; 7.4uM; PC3; HT_HG-U133A | 3.23e-06 | 194 | 48 | 6 | 4320_DN | |
| Drug | Proparacaine hydrochloride [5875-06-9]; Down 200; 12uM; PC3; HT_HG-U133A | 3.63e-06 | 198 | 48 | 6 | 6332_DN | |
| Drug | 1-octyl-3-methylimidazolium tetrafluoroborate | 1.30e-05 | 3 | 48 | 2 | CID011460221 | |
| Drug | hmimBF4 | 1.30e-05 | 3 | 48 | 2 | CID002734179 | |
| Drug | Sulfaphenazole [526-08-9]; Down 200; 12.8uM; MCF7; HT_HG-U133A | 4.33e-05 | 185 | 48 | 5 | 1673_DN | |
| Drug | emimBF4 | 4.33e-05 | 5 | 48 | 2 | CID002769348 | |
| Drug | Cloperastine hydrochloride [14984-68-0]; Down 200; 11uM; PC3; HT_HG-U133A | 4.79e-05 | 189 | 48 | 5 | 4271_DN | |
| Drug | Gabexate mesilate [56974-61-9]; Down 200; 9.6uM; HL60; HT_HG-U133A | 5.04e-05 | 191 | 48 | 5 | 2937_DN | |
| Drug | Suramin sodium salt; Down 200; 10uM; PC3; HT_HG-U133A | 5.42e-05 | 194 | 48 | 5 | 7529_DN | |
| Drug | Indapamide [26807-65-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A | 5.42e-05 | 194 | 48 | 5 | 3859_DN | |
| Drug | Flutamide [13311-84-7]; Down 200; 14.4uM; MCF7; HT_HG-U133A | 5.42e-05 | 194 | 48 | 5 | 4361_DN | |
| Drug | Benfotiamine [22457-89-2]; Down 200; 8.6uM; PC3; HT_HG-U133A | 5.42e-05 | 194 | 48 | 5 | 4312_DN | |
| Drug | Flumethasone [2135-17-3]; Down 200; 9.8uM; PC3; HT_HG-U133A | 5.42e-05 | 194 | 48 | 5 | 4272_DN | |
| Drug | 16-phenyl tetranor Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A | 5.56e-05 | 195 | 48 | 5 | 7509_DN | |
| Drug | Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Down 200; 5.8uM; PC3; HT_HG-U133A | 5.56e-05 | 195 | 48 | 5 | 4508_DN | |
| Drug | Liothyronine [6893-02-3]; Down 200; 6.2uM; PC3; HT_HG-U133A | 5.70e-05 | 196 | 48 | 5 | 6602_DN | |
| Drug | Midecamycin [35457-80-8]; Down 200; 5uM; MCF7; HT_HG-U133A | 5.83e-05 | 197 | 48 | 5 | 1526_DN | |
| Drug | Beta-sistosterol [83-46-5]; Down 200; 9.6uM; MCF7; HT_HG-U133A | 5.83e-05 | 197 | 48 | 5 | 7332_DN | |
| Drug | Ciprofibrate [52214-84-3]; Up 200; 13.8uM; MCF7; HT_HG-U133A | 6.12e-05 | 199 | 48 | 5 | 3561_UP | |
| Drug | Moxisylyte hydrochoride [964-52-3]; Up 200; 12.6uM; HL60; HT_HG-U133A | 6.27e-05 | 200 | 48 | 5 | 1846_UP | |
| Drug | 4-vinylcyclohexene diepoxide | 7.11e-05 | 105 | 48 | 4 | CID000007833 | |
| Drug | cathinone | 8.22e-05 | 40 | 48 | 3 | CID000062258 | |
| Drug | Chloroprene | DACH1 CCAR1 NCOR1 SIX4 PUM1 SHROOM2 MINDY2 TBL1XR1 SGCB PRPF40A EMSY | 8.92e-05 | 1348 | 48 | 11 | ctd:D002737 |
| Drug | cyclopamine | 1.25e-04 | 46 | 48 | 3 | ctd:C000541 | |
| Disease | sensory system disease (implicated_via_orthology) | 7.44e-06 | 3 | 47 | 2 | DOID:0050155 (implicated_via_orthology) | |
| Disease | myotonic dystrophy type 1 (implicated_via_orthology) | 3.71e-05 | 6 | 47 | 2 | DOID:11722 (implicated_via_orthology) | |
| Disease | asthma, age at onset | 1.92e-04 | 70 | 47 | 3 | EFO_0004847, MONDO_0004979 | |
| Disease | Antihistamine use measurement | 3.33e-04 | 17 | 47 | 2 | EFO_0009943 | |
| Disease | rhinitis | 3.33e-04 | 17 | 47 | 2 | EFO_0008521 | |
| Disease | Inhalant adrenergic use measurement | 4.88e-04 | 96 | 47 | 3 | EFO_0009941 | |
| Disease | triacylglycerol 52:6 measurement | 7.28e-04 | 25 | 47 | 2 | EFO_0010418 | |
| Disease | adult onset asthma | 8.89e-04 | 118 | 47 | 3 | EFO_1002011 | |
| Disease | Lymphoma, Non-Hodgkin | 1.19e-03 | 32 | 47 | 2 | C0024305 | |
| Disease | Global developmental delay | 1.26e-03 | 133 | 47 | 3 | C0557874 | |
| Disease | nasal disorder | 1.43e-03 | 35 | 47 | 2 | MONDO_0002436 | |
| Disease | triacylglycerol 52:5 measurement | 1.43e-03 | 35 | 47 | 2 | EFO_0010417 | |
| Disease | Glucocorticoid use measurement | 1.77e-03 | 39 | 47 | 2 | EFO_0009942 | |
| Disease | Breast adenocarcinoma | 1.96e-03 | 41 | 47 | 2 | C0858252 | |
| Disease | Neoplasm of uncertain or unknown behavior of breast | 1.96e-03 | 41 | 47 | 2 | C0496956 | |
| Disease | childhood onset asthma | 1.96e-03 | 334 | 47 | 4 | MONDO_0005405 | |
| Disease | cognitive function measurement, self reported educational attainment | 2.44e-03 | 355 | 47 | 4 | EFO_0004784, EFO_0008354 | |
| Disease | Acute Promyelocytic Leukemia | 2.46e-03 | 46 | 47 | 2 | C0023487 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| AAAAAAAANLDSAQS | 46 | Q99626 | |
| TAALQQQAAAAAAAL | 66 | Q8IX12 | |
| AAAAAAAATNAAIAE | 326 | Q9UI36 | |
| NAAAAAAAAFTASSQ | 56 | Q9UKD1 | |
| QHQAQAAQAAAAAIS | 291 | P43699 | |
| AAAAAAAAQAAALQL | 386 | Q86U06 | |
| AAAAAAAQAAAAAQA | 376 | Q16676 | |
| AKSAAQAAAQTNSNA | 51 | Q8NC51 | |
| AAGQVAAASAAAAVV | 236 | Q01851 | |
| AAAAAAAAAAAAQQQ | 91 | Q9H1B7 | |
| AAQESAAAAAAAAAA | 91 | P56270 | |
| VVAAAAAAAVAAQGV | 36 | P10070 | |
| AVAAGANPAAAAAAN | 311 | Q9UNW9 | |
| QAAQQAQLAAASASA | 146 | Q01658 | |
| AQLAAASASASNQAG | 151 | Q01658 | |
| ASLFQQQAAAAAAAT | 471 | Q14671 | |
| SSAAQAAVAAAAASA | 591 | Q14671 | |
| VAAAAAAAAAAAAAN | 281 | O75400 | |
| AAAAAAAAANANAST | 286 | O75400 | |
| TVAAQAQALAAQAAA | 76 | Q9BTU6 | |
| AQALAAQAAAAAHAA | 81 | Q9BTU6 | |
| VAAAAAAAAAASLQV | 6 | Q9NVR0 | |
| AAAAAAAAAVAEQVS | 211 | Q12873 | |
| QATAEANNLAAVAGA | 376 | Q8NHH9 | |
| ANQAAVAAQAAAAAA | 251 | Q5VZF2 | |
| AFTVTANAVANAAIQ | 111 | Q7Z589 | |
| MAAQAAAAAQAAAAQ | 1 | Q9Y6X3 | |
| AAAAQAAAAQAAQAE | 6 | Q9Y6X3 | |
| AAAAASANPAAAAAN | 346 | P51513 | |
| QAAAAAAAASTQAQQ | 566 | Q8NBR6 | |
| AQSQAKAVAAAVAAA | 506 | P84550 | |
| NEAAAASAAAAAATE | 591 | O75376 | |
| AATAQAAAAAQAAAV | 451 | Q13485 | |
| AVAAAAAGAAADQVQ | 71 | Q9UIU6 | |
| SEAAAAQHFTALAQA | 341 | Q13796 | |
| AAANAASTAASSAAQ | 316 | O15126 | |
| ADIQLNSSNVAAAAA | 861 | P42338 | |
| NSSNVAAAAAFNKDA | 866 | P42338 | |
| NLLASSSAAAAAAEQ | 246 | Q9ULL5 | |
| MAAAAAAAAEQQSSN | 1 | Q16585 | |
| AHQNSAVAAAAAAAA | 291 | O00570 | |
| SARAAAAFVLANENN | 201 | O60518 | |
| SVAAAAAAAAAAAAN | 71 | P31271 | |
| QQAAAAAAAAAAASQ | 106 | Q9BZK7 | |
| AAAAAAAASQQGSAK | 111 | Q9BZK7 | |
| QAAAVQAAAAQAAVA | 426 | Q99856 | |
| QAAAAQAAVAAQAAA | 431 | Q99856 | |
| QQQASAAAAAAAATA | 156 | O60907 | |
| AAAAAAAVAQAQAQA | 466 | Q8TF68 | |
| NAAASAVNATASAVT | 2726 | Q96T58 | |
| AAAAAAAGVSQAAVL | 6 | Q2M3V2 | |
| SLAAAAAAAAAEQQV | 31 | Q15904 | |
| ASASADFDAQAVNVQ | 1076 | Q9BZZ2 | |
| QAAAAAAVAAAAATA | 146 | Q8NF64 | |
| QQKQAAAAAAAAAAT | 286 | Q96KR1 | |
| TVLQQHAAAAAAAAA | 1101 | Q7Z570 |