Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3 RIMBP3C RIMBP3B	5.84e-08	5	37	3	GO:0030156
GeneOntologyMolecularFunction	alpha-1,4-glucosidase activity	SI MGAM	3.33e-05	5	37	2	GO:0004558
GeneOntologyMolecularFunction	alpha-glucosidase activity	SI MGAM	6.97e-05	7	37	2	GO:0090599
GeneOntologyMolecularFunction	glucosidase activity	SI MGAM	3.46e-04	15	37	2	GO:0015926
GeneOntologyMolecularFunction	hydrolase activity, hydrolyzing O-glycosyl compounds	SI MGAM OTOGL	9.12e-04	103	37	3	GO:0004553
GeneOntologyMolecularFunction	hydrolase activity, acting on glycosyl bonds	SI MGAM OTOGL	2.38e-03	144	37	3	GO:0016798
GeneOntologyBiologicalProcess	disaccharide catabolic process	SI MGAM	1.87e-05	4	37	2	GO:0046352
GeneOntologyBiologicalProcess	neuromuscular synaptic transmission	RIMBP3 RIMBP3C RIMBP3B	3.64e-05	36	37	3	GO:0007274
GeneOntologyCellularComponent	manchette	RIMBP3 RIMBP3C RIMBP3B	1.62e-05	28	37	3	GO:0002177
GeneOntologyCellularComponent	interstitial matrix	CCDC80 MAMDC2	4.08e-04	17	37	2	GO:0005614
GeneOntologyCellularComponent	cluster of actin-based cell projections	SLC7A9 SI FLNA RSPH9	6.32e-04	223	37	4	GO:0098862
MousePheno	ectopic manchette	RIMBP3 RIMBP3C RIMBP3B	8.44e-06	19	30	3	MP:0009377
MousePheno	detached sperm flagellum	RIMBP3 RIMBP3C RIMBP3B	1.16e-05	21	30	3	MP:0008893
MousePheno	detached acrosome	RIMBP3 RIMBP3C RIMBP3B	1.11e-04	44	30	3	MP:0009231
MousePheno	abnormal manchette morphology	RIMBP3 RIMBP3C RIMBP3B	1.19e-04	45	30	3	MP:0009376
MousePheno	absent intervertebral disk	GLI2 KIAA1217	1.24e-04	8	30	2	MP:0004683
MousePheno	kinked sperm flagellum	RIMBP3 RIMBP3C RIMBP3B	2.29e-04	56	30	3	MP:0009237
MousePheno	abnormal notochord morphology	FOXA2 GLI2 KIAA1217	3.25e-04	63	30	3	MP:0002825
Domain	Glyco_hydro_31_CS	SI MGAM	2.16e-05	4	36	2	IPR030459
Domain	NtCtMGAM_N	SI MGAM	2.16e-05	4	36	2	PF16863
Domain	Gal_mutarotase_N	SI MGAM	2.16e-05	4	36	2	IPR031727
Domain	GLYCOSYL_HYDROL_F31_2	SI MGAM	3.60e-05	5	36	2	PS00707
Domain	Glyco_hydro_31_AS	SI MGAM	5.39e-05	6	36	2	IPR030458
Domain	Glyco_hydro_31	SI MGAM	7.54e-05	7	36	2	PF01055
Domain	Glyco_hydro_31	SI MGAM	7.54e-05	7	36	2	IPR000322
Domain	GLYCOSYL_HYDROL_F31_1	SI MGAM	7.54e-05	7	36	2	PS00129
Domain	Trefoil	SI MGAM	1.00e-04	8	36	2	PF00088
Domain	P_TREFOIL_1	SI MGAM	1.00e-04	8	36	2	PS00025
Domain	P_trefoil_CS	SI MGAM	1.00e-04	8	36	2	IPR017957
Domain	P_TREFOIL_2	SI MGAM	1.29e-04	9	36	2	PS51448
Domain	PD	SI MGAM	1.29e-04	9	36	2	SM00018
Domain	-	SI MGAM	1.97e-04	11	36	2	4.10.110.10
Domain	P_trefoil_dom	SI MGAM	2.36e-04	12	36	2	IPR000519
Domain	SH3_9	RIMBP3 RIMBP3C RIMBP3B	4.53e-04	78	36	3	PF14604
Domain	Gal_mutarotase_SF_dom	SI MGAM	4.82e-04	17	36	2	IPR011013
Domain	SH3_2	RIMBP3 RIMBP3C RIMBP3B	6.03e-04	86	36	3	IPR011511
Domain	SH3_2	RIMBP3 RIMBP3C RIMBP3B	6.03e-04	86	36	3	PF07653
Domain	-	RIMBP3 FLNA RIMBP3C PXDN RIMBP3B MUSK	1.53e-03	663	36	6	2.60.40.10
Domain	Abhydrolase_1	SERHL2 SERHL	1.62e-03	31	36	2	PF00561
Domain	AB_hydrolase_1	SERHL2 SERHL	1.84e-03	33	36	2	IPR000073
Domain	Ig-like_fold	RIMBP3 FLNA RIMBP3C PXDN RIMBP3B MUSK	2.11e-03	706	36	6	IPR013783
Domain	Glycoside_hydrolase_SF	SI MGAM	4.68e-03	53	36	2	IPR017853
Domain	FN3	RIMBP3 RIMBP3C RIMBP3B	6.57e-03	199	36	3	PS50853
Domain	FN3_dom	RIMBP3 RIMBP3C RIMBP3B	7.52e-03	209	36	3	IPR003961
Domain	SH3	RIMBP3 RIMBP3C RIMBP3B	8.22e-03	216	36	3	PS50002
Domain	SH3	RIMBP3 RIMBP3C RIMBP3B	8.22e-03	216	36	3	SM00326
Domain	SH3_domain	RIMBP3 RIMBP3C RIMBP3B	8.65e-03	220	36	3	IPR001452
Pathway	PID_HEDGEHOG_GLI_PATHWAY	FOXA2 GLI2 HDAC1	6.25e-05	48	23	3	M219
Pathway	REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE	SI MGAM	7.09e-05	8	23	2	MM14717
Pathway	REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE	SI MGAM	1.39e-04	11	23	2	M1091
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	4.81e-09	4	38	3	19091768
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3 RIMBP3C RIMBP3B	1.20e-08	5	38	3	17855024
Pubmed	Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.	RIMBP3 RIMBP3C RIMBP3B	4.34e-07	14	38	3	17662146
Pubmed	Contribution of the Individual Small Intestinal α-Glucosidases to Digestion of Unusual α-Linked Glycemic Disaccharides.	SI MGAM	1.16e-06	2	38	2	27480812
Pubmed	Interaction between the α-glucosidases, sucrase-isomaltase and maltase-glucoamylase, in human intestinal brush border membranes and its potential impact on disaccharide digestion.	SI MGAM	1.16e-06	2	38	2	36968271
Pubmed	Structural basis for substrate selectivity in human maltase-glucoamylase and sucrase-isomaltase N-terminal domains.	SI MGAM	1.16e-06	2	38	2	20356844
Pubmed	Identification of Serhl, a new member of the serine hydrolase family induced by passive stretch of skeletal muscle in vivo.	SERHL2 SERHL	1.16e-06	2	38	2	11352564
Pubmed	Transcriptional activation of Hedgehog pathway components in aggressive haemangioma.	FOXA2 GLI2	3.48e-06	3	38	2	28370639
Pubmed	Activation of Hedgehog Signaling in Aggressive Hepatic Hemangioma in Newborns and Infants.	FOXA2 GLI2	3.48e-06	3	38	2	31092427
Pubmed	Partial characterization of murine intestinal maltase-glucoamylase.	SI MGAM	3.48e-06	3	38	2	12150962
Pubmed	The stem cell-associated transcription co-factor, ZNF521, interacts with GLI1 and GLI2 and enhances the activity of the Sonic hedgehog pathway.	GLI2 HDAC1	6.96e-06	4	38	2	31558698
Pubmed	The PCP protein Vangl2 regulates migration of hindbrain motor neurons by acting in floor plate cells, and independently of cilia function.	FOXA2 GLI2	6.96e-06	4	38	2	23988578
Pubmed	Regulation of adipogenesis by nuclear receptor PPARγ is modulated by the histone demethylase JMJD2C.	KDM4C HDAC1	6.96e-06	4	38	2	21637537
Pubmed	A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro.	FOXA2 GLI2	1.16e-05	5	38	2	9118802
Pubmed	Gli1 is a target of Sonic hedgehog that induces ventral neural tube development.	FOXA2 GLI2	1.16e-05	5	38	2	9216996
Pubmed	Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus.	FOXA2 GLI2	2.43e-05	7	38	2	9731531
Pubmed	Regulation of mouse-renin gene by apurinic/apyrimidinic-endonuclease 1 (APE1/Ref-1) via recruitment of histone deacetylase 1 corepressor complex.	REN HDAC1	2.43e-05	7	38	2	22441348
Pubmed	Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3.	GLI2 HDAC1	2.43e-05	7	38	2	12435627
Pubmed	Rab34 small GTPase is required for Hedgehog signaling and an early step of ciliary vesicle formation in mouse.	FOXA2 GLI2	3.24e-05	8	38	2	30301781
Pubmed	Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation.	GLI2 HDAC1	4.16e-05	9	38	2	20081843
Pubmed	Context-dependent ciliary regulation of hedgehog pathway repression in tissue morphogenesis.	FOXA2 GLI2	4.16e-05	9	38	2	37943875
Pubmed	Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia.	FOXA2 GLI2	4.16e-05	9	38	2	25083987
Pubmed	Loss of Asb2 Impairs Cardiomyocyte Differentiation and Leads to Congenital Double Outlet Right Ventricle.	FLNA FOXA2	4.16e-05	9	38	2	32179481
Pubmed	Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation.	FOXA2 GLI2	4.16e-05	9	38	2	10725236
Pubmed	Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway.	FOXA2 GLI2	4.16e-05	9	38	2	12361967
Pubmed	The loss of Hh responsiveness by a non-ciliary Gli2 variant.	FOXA2 GLI2	4.16e-05	9	38	2	25834022
Pubmed	Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube.	FOXA2 GLI2	4.16e-05	9	38	2	20516201
Pubmed	Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.	ZNF326 HNRNPF KIAA1217 HDAC1	4.18e-05	177	38	4	26206133
Pubmed	Patched1 patterns Fibroblast growth factor 10 and Forkhead box F1 expression during pulmonary branch formation.	FOXA2 GLI2	5.20e-05	10	38	2	28939119
Pubmed	Antagonistic and cooperative actions of Kif7 and Sufu define graded intracellular Gli activities in Hedgehog signaling.	FOXA2 GLI2	5.20e-05	10	38	2	23166838
Pubmed	Differential requirement for Gli2 and Gli3 in ventral neural cell fate specification.	FOXA2 GLI2	5.20e-05	10	38	2	12812795
Pubmed	Control of cell pattern in the neural tube by the zinc finger transcription factor and oncogene Gli-1.	FOXA2 GLI2	5.20e-05	10	38	2	9247260
Pubmed	Suppressor of Fused Chaperones Gli Proteins To Generate Transcriptional Responses to Sonic Hedgehog Signaling.	FOXA2 GLI2	5.20e-05	10	38	2	27849569
Pubmed	Gli1 can rescue the in vivo function of Gli2.	FOXA2 GLI2	5.20e-05	10	38	2	11748151
Pubmed	PKA-mediated Gli2 and Gli3 phosphorylation is inhibited by Hedgehog signaling in cilia and reduced in Talpid3 mutant.	FOXA2 GLI2	6.35e-05	11	38	2	28673820
Pubmed	Distinct Activities of Gli1 and Gli2 in the Absence of Ift88 and the Primary Cilia.	FOXA2 GLI2	6.35e-05	11	38	2	30791390
Pubmed	Mouse Rab23 regulates hedgehog signaling from smoothened to Gli proteins.	FOXA2 GLI2	6.35e-05	11	38	2	16364285
Pubmed	Sonic hedgehog signaling directs patterned cell remodeling during cranial neural tube closure.	FOXA2 GLI2	6.35e-05	11	38	2	33103996
Pubmed	IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture.	FOXA2 GLI2	7.62e-05	12	38	2	28264835
Pubmed	Dual function of suppressor of fused in Hh pathway activation and mouse spinal cord patterning.	FOXA2 GLI2	7.62e-05	12	38	2	22182519
Pubmed	IFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transport.	FOXA2 GLI2	7.62e-05	12	38	2	22595669
Pubmed	Spop regulates Gli3 activity and Shh signaling in dorsoventral patterning of the mouse spinal cord.	FOXA2 GLI2	7.62e-05	12	38	2	28412462
Pubmed	The novel ciliogenesis regulator DYRK2 governs Hedgehog signaling during mouse embryogenesis.	FOXA2 GLI2	7.62e-05	12	38	2	32758357
Pubmed	Increased proteolytic processing of full-length Gli2 transcription factor reduces the hedgehog pathway activity in vivo.	FOXA2 GLI2	7.62e-05	12	38	2	21337666
Pubmed	Foxa1 and Foxa2 positively and negatively regulate Shh signalling to specify ventral midbrain progenitor identity.	FOXA2 GLI2	9.00e-05	13	38	2	21093585
Pubmed	T396I mutation of mouse Sufu reduces the stability and activity of Gli3 repressor.	FOXA2 GLI2	9.00e-05	13	38	2	25760946
Pubmed	Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice.	FOXA2 GLI2	9.00e-05	13	38	2	9636069
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	DUSP29 MUSK KIAA1217 WIPI2 HDAC1	9.07e-05	420	38	5	28065597
Pubmed	Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors.	FOXA2 GLI2	1.05e-04	14	38	2	20463034
Pubmed	Small ubiquitin-like Modifier (SUMO) modification inhibits GLI2 protein transcriptional activity in vitro and in vivo.	FOXA2 GLI2	1.05e-04	14	38	2	22549777
Pubmed	Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling.	FOXA2 GLI2	1.05e-04	14	38	2	19666503
Pubmed	Complex interactions between genes controlling trafficking in primary cilia.	FOXA2 GLI2	1.05e-04	14	38	2	21552265
Pubmed	Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function.	FOXA2 GLI2	1.05e-04	14	38	2	21664576
Pubmed	A predictive model of bifunctional transcription factor signaling during embryonic tissue patterning.	FOXA2 GLI2	1.21e-04	15	38	2	25458012
Pubmed	Functional redundancy of frizzled 3 and frizzled 6 in planar cell polarity control of mouse hair follicles.	SERHL2 SERHL	1.21e-04	15	38	2	30237242
Pubmed	Three Tctn proteins are functionally conserved in the regulation of neural tube patterning and Gli3 processing but not ciliogenesis and Hedgehog signaling in the mouse.	FOXA2 GLI2	1.38e-04	16	38	2	28800946
Pubmed	Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system.	FOXA2 GLI2	1.38e-04	16	38	2	9655799
Pubmed	The ciliary phosphatidylinositol phosphatase Inpp5e plays positive and negative regulatory roles in Shh signaling.	FOXA2 GLI2	1.38e-04	16	38	2	31964774
Pubmed	Identification and characterization of VPO1, a new animal heme-containing peroxidase.	PXDN FOXA2	1.38e-04	16	38	2	18929642
Pubmed	Ciliary and extraciliary Gpr161 pools repress hedgehog signaling in a tissue-specific manner.	FOXA2 GLI2	1.38e-04	16	38	2	34346313
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	SI MGAM FLNA GPRC5C PXDN CDH15 PSMB2	1.40e-04	1070	38	7	23533145
Pubmed	Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis.	FOXA2 HDAC1	1.76e-04	18	38	2	14645126
Pubmed	The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling.	FOXA2 GLI2	1.96e-04	19	38	2	23332756
Pubmed	Forward genetics uncovers Transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signaling.	FOXA2 GLI2	1.96e-04	19	38	2	22698544
Pubmed	Quantitative lineage analysis identifies a hepato-pancreato-biliary progenitor niche.	FOXA2 GLI2	1.96e-04	19	38	2	34433966
Pubmed	Cell Cycle-Related Kinase (CCRK) regulates ciliogenesis and Hedgehog signaling in mice.	FOXA2 GLI2	1.96e-04	19	38	2	28817564
Pubmed	Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut.	FOXA2 GLI2	1.96e-04	19	38	2	19686689
Pubmed	Loss of dynein-2 intermediate chain Wdr34 results in defects in retrograde ciliary protein trafficking and Hedgehog signaling in the mouse.	FOXA2 GLI2	2.18e-04	20	38	2	28379358
Pubmed	Disruption of Mks1 localization to the mother centriole causes cilia defects and developmental malformations in Meckel-Gruber syndrome.	FOXA2 GLI2	2.18e-04	20	38	2	21045211
Pubmed	Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling.	FOXA2 GLI2	2.18e-04	20	38	2	32702291
Pubmed	Temporal and spatial requirements of Smoothened in ventral midbrain neuronal development.	FOXA2 GLI2	2.41e-04	21	38	2	23618354
Pubmed	Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis.	FOXA2 GLI2	2.41e-04	21	38	2	32855417
Pubmed	Synergistic co-regulation and competition by a SOX9-GLI-FOXA phasic transcriptional network coordinate chondrocyte differentiation transitions.	FOXA2 GLI2	2.41e-04	21	38	2	29659575
Pubmed	Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube.	FOXA2 GLI2	2.41e-04	21	38	2	22007132
Pubmed	Differential requirement of SUFU in tissue development discovered in a hypomorphic mouse model.	FOXA2 GLI2	2.41e-04	21	38	2	28688895
Pubmed	Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway.	FOXA2 GLI2	2.65e-04	22	38	2	19223390
Pubmed	Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction.	FOXA2 GLI2	2.65e-04	22	38	2	20159594
Pubmed	Cbln1 regulates axon growth and guidance in multiple neural regions.	FOXA2 GLI2	2.65e-04	22	38	2	36395107
Pubmed	Tcf/Lef repressors differentially regulate Shh-Gli target gene activation thresholds to generate progenitor patterning in the developing CNS.	FOXA2 GLI2	2.65e-04	22	38	2	21775418
Pubmed	Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway.	FOXA2 GLI2	2.90e-04	23	38	2	16459298
Pubmed	Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis.	FOXA2 GLI2	2.90e-04	23	38	2	30814516
Pubmed	Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development.	GLI2 HDAC1	2.90e-04	23	38	2	21937600
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TANC2 RBSN ZNF326 DPP8 MUSK KIAA1217	3.18e-04	861	38	6	36931259
Pubmed	Wnt signaling determines ventral spinal cord cell fates in a time-dependent manner.	FOXA2 GLI2	3.43e-04	25	38	2	18927156
Pubmed	Centrosomal protein Dzip1l binds Cby, promotes ciliary bud formation, and acts redundantly with Bromi to regulate ciliogenesis in the mouse.	FOXA2 GLI2	3.43e-04	25	38	2	29487109
Pubmed	Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation.	FOXA2 KDM4C	3.72e-04	26	38	2	28087629
Pubmed	Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos.	FOXA2 GLI2	3.72e-04	26	38	2	37228654
Pubmed	Early mouse caudal development relies on crosstalk between retinoic acid, Shh and Fgf signalling pathways.	FOXA2 GLI2	4.01e-04	27	38	2	19168680
Pubmed	Forkhead box F2 regulation of platelet-derived growth factor and myocardin/serum response factor signaling is essential for intestinal development.	FOXA2 GLI2	4.01e-04	27	38	2	25631042
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	FLNA ZNF326 HNRNPF HDAC1 PSMB2	4.13e-04	583	38	5	29844126
Pubmed	Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development.	FOXA2 GLI2	4.32e-04	28	38	2	26884322
Pubmed	The small GTPase RSG1 controls a final step in primary cilia initiation.	FOXA2 GLI2	4.32e-04	28	38	2	29038301
Pubmed	A Retinoic Acid-Hedgehog Cascade Coordinates Mesoderm-Inducing Signals and Endoderm Competence during Lung Specification.	FOXA2 GLI2	4.63e-04	29	38	2	27320915
Pubmed	Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components.	FOXA2 GLI2	4.63e-04	29	38	2	21209331
Pubmed	Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells.	FOXA2 GLI2	4.96e-04	30	38	2	25804738
Pubmed	Floor plate-derived sonic hedgehog regulates glial and ependymal cell fates in the developing spinal cord.	FOXA2 GLI2	4.96e-04	30	38	2	23482494
Pubmed	Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton.	FOXA2 GLI2	4.96e-04	30	38	2	24302887
Pubmed	Expression of early developmental markers predicts the efficiency of embryonic stem cell differentiation into midbrain dopaminergic neurons.	FOXA2 GLI2	5.30e-04	31	38	2	22889265
Pubmed	Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling.	FOXA2 GLI2	5.65e-04	32	38	2	19286674
Pubmed	ZBTB18 inhibits SREBP-dependent lipid synthesis by halting CTBPs and LSD1 activity in glioblastoma.	FLNA HDAC1	6.01e-04	33	38	2	36414381
Interaction	CCDC6 interactions	RIMBP3 C1S FLNA HNRNPF KIAA1217 HDAC1	1.24e-05	286	37	6	int:CCDC6
Cytoband	22q11.21	RIMBP3 RIMBP3C RIMBP3B	1.09e-04	111	38	3	22q11.21
Cytoband	10q22.2	MSS51 DUSP29	5.36e-04	41	38	2	10q22.2
Cytoband	Ensembl 112 genes in cytogenetic band chr22q11	RIMBP3 RIMBP3C RIMBP3B	5.02e-03	419	38	3	chr22q11
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	PXDN MUSK	1.48e-02	161	21	2	593
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C1S FLNA GPRC5C DUSP29 OTOGL	4.87e-07	184	38	5	89ae8bf1a6c2d355d279d23a5e24a08d9ec2334e
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C1S FLNA GPRC5C DUSP29 OTOGL	4.87e-07	184	38	5	34c84ac9a32eaf96f45b79485119cad65905817d
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Stroma____kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C1S CCDC80 REN DUSP29 MAMDC2	5.86e-07	191	38	5	8597a8af294f24496c317d995f07eb5dcc25c13c
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C1S CCDC80 REN DUSP29 MAMDC2	6.33e-07	194	38	5	80be44e9ddd9f6ddd9dff7cba0eb457431204c2d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	C1S CCDC80 PXDN GLI2 KIAA1217	6.33e-07	194	38	5	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	COVID-19-Heart-Fib_1\|Heart / Disease (COVID-19 only), tissue and cell type	C1S CCDC80 PXDN MAMDC2 MUSK	6.49e-07	195	38	5	f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	C1S CCDC80 MAMDC2 GLI2 MUSK	6.66e-07	196	38	5	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	nucseq-Mesenchymal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	C1S CCDC80 MAMDC2 GLI2 MUSK	7.00e-07	198	38	5	8f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCell	Frontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	C1S DUSP29 OTOGL MAMDC2	1.00e-06	89	38	4	42432936a6b4289cc4b42fcb576fb09073f2264b
ToppCell	Frontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	C1S DUSP29 OTOGL MAMDC2	1.00e-06	89	38	4	6c594e13f169970b337c2fc3ab969faf6db1a27a
ToppCell	C_02\|World / shred on cell type and cluster	SLC7A9 OVOS2 SI MGAM	1.17e-05	165	38	4	a456c2c9ffe8dc91e17cac84ba87b88e016f8e6d
ToppCell	Club_cells-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	MGAM CCDC80 PXDN GLI2	1.28e-05	169	38	4	03b303af8a26c6ff196507fe24f5bd3d75d7b1af
ToppCell	Globus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	C1S FLNA GPRC5C MAMDC2	1.41e-05	173	38	4	51328a60ffaf34fa0f7df6084d348b5efc9917f5
ToppCell	Globus_pallidus-Endothelial-MURAL\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	C1S FLNA GPRC5C MAMDC2	1.41e-05	173	38	4	b77cd5dbda3a206922f20224f4e10a3bf712f7db
ToppCell	Entopeduncular-Endothelial-MURAL\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FLNA GPRC5C DUSP29 MAMDC2	1.51e-05	176	38	4	b8e52bec78876562a25f0b0de502aa9372b28bd2
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FLNA GPRC5C DUSP29 MAMDC2	1.51e-05	176	38	4	10c1f31c27e54b70f58f0b0086ac74dee2ce4197
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	C1S CCDC80 REN CPT1C	1.54e-05	177	38	4	30f82b04e48940bfcaf2c22677efe6d57ae3f1a7
ToppCell	5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA PXDN MAMDC2 CPT1C	1.54e-05	177	38	4	e65c0568dc5852108e9802273499bc7cf88fafab
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	C1S PXDN GLI2 KIAA1217	1.57e-05	178	38	4	78a0c6340001a77f5b2d890b6263f574af2e72da
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CCDC80 MAMDC2 GLI2 CDH15	1.57e-05	178	38	4	e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	GPRC5C DUSP29 MAMDC2 CDH15	1.72e-05	182	38	4	ba066ff9029cc052b76e2330ec168cb2e9b7e498
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C1S CCDC80 OTOGL MAMDC2	1.75e-05	183	38	4	2beb5414958d38a5341870d55229f3b1707e76bf
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C1S FLNA PXDN MAMDC2	1.75e-05	183	38	4	af8d86f15a549064530d94bd47081daf59d58ecd
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	CCDC80 PXDN MAMDC2 GLI2	1.91e-05	187	38	4	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C1S CCDC80 GLI2 KIAA1217	1.95e-05	188	38	4	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CCDC80 PXDN MAMDC2 MUSK	1.95e-05	188	38	4	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C1S PXDN GLI2 KIAA1217	1.99e-05	189	38	4	71397e993a77d70b2eeede240bdfc7660b558987
ToppCell	droplet-Kidney-nan-3m-Epithelial-Stroma____kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C1S CCDC80 REN MAMDC2	1.99e-05	189	38	4	a959c9d6a0866582688a4204d625c1e5a123e93d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C1S PXDN GLI2 KIAA1217	1.99e-05	189	38	4	4eea4759520c312bd17a681034d8074e47093d2b
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	CCDC80 MAMDC2 GLI2 MUSK	2.03e-05	190	38	4	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C1S CCDC80 GLI2 KIAA1217	2.03e-05	190	38	4	efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell	10x5'v1-week_14-16-Myeloid_macrophage-stroma-erythroid_macrophage\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CCDC80 GPRC5C MAMDC2 CDH15	2.03e-05	190	38	4	cf463b2f227f3cc7d3fd296c810c0cbe51cbee72
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C1S FOXA2 MAMDC2 CDH15	2.08e-05	191	38	4	f00d6824bd138b192a996e9f7de57b235bb24c18
ToppCell	LV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	C1S CCDC80 MAMDC2 MUSK	2.08e-05	191	38	4	d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCell	facs-MAT\|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C1S MAMDC2 GLI2 MUSK	2.08e-05	191	38	4	b4fba92f9bd1354a07fedfca7304a3757e6d5beb
ToppCell	ASK440-Mesenchymal-Fibroblast\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	C1S CCDC80 MAMDC2 GLI2	2.08e-05	191	38	4	387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCell	ASK440-Mesenchymal\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	C1S CCDC80 MAMDC2 GLI2	2.08e-05	191	38	4	f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C1S CCDC80 GLI2 KIAA1217	2.12e-05	192	38	4	5105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	C1S CCDC80 GLI2 KIAA1217	2.12e-05	192	38	4	d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C1S CCDC80 REN MAMDC2	2.12e-05	192	38	4	3617d2bc7e33d981f3ec349e9962d8d4bd822fbd
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	C1S CCDC80 MAMDC2 MUSK	2.12e-05	192	38	4	356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	C1S CCDC80 MAMDC2 GLI2	2.16e-05	193	38	4	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	LA\|World / Chamber and Cluster_Paper	CCDC80 PXDN MAMDC2 GLI2	2.16e-05	193	38	4	d4bf89437216baf489ea0239136dcedf3b6714af
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	C1S CCDC80 MAMDC2 MUSK	2.16e-05	193	38	4	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C1S CCDC80 MAMDC2 MUSK	2.16e-05	193	38	4	7c0d84b92470bfda2db1e5007feee7c1235a0a78
ToppCell	COVID-19-Heart-Fib_2\|Heart / Disease (COVID-19 only), tissue and cell type	C1S CCDC80 PXDN GLI2	2.21e-05	194	38	4	d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell	RV-02._Fibroblast_II\|RV / Chamber and Cluster_Paper	C1S CCDC80 MAMDC2 MUSK	2.21e-05	194	38	4	11c79a8c56ece42713b04b321982e41e239f07a5
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	C1S CCDC80 MAMDC2 GLI2	2.21e-05	194	38	4	7826fe5eb254ac032de0d978f39585a40e0b3ee4
ToppCell	droplet-Pancreas-Exocrine-21m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C1S FLNA CCDC80 PXDN	2.21e-05	194	38	4	04ecb609d233a4b12e275c604810937830363e17
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	C1S CCDC80 MAMDC2 GLI2	2.21e-05	194	38	4	ca1f24070424b44b7a442e4fca761ebfbe24b063
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C1S FLNA GPRC5C MAMDC2	2.21e-05	194	38	4	bf34737ae2dc218f890fbb9201c308b324415749
ToppCell	droplet-Pancreas-Exocrine-21m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C1S FLNA CCDC80 PXDN	2.21e-05	194	38	4	775600880bb77781de48085d8744c1030223de1f
ToppCell	LV-02._Fibroblast_II\|LV / Chamber and Cluster_Paper	C1S CCDC80 MAMDC2 MUSK	2.21e-05	194	38	4	014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C1S FLNA GPRC5C MAMDC2	2.21e-05	194	38	4	b35e33439b6d3b5d69147e617224d2c8fd056223
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C1S FLNA GPRC5C MAMDC2	2.21e-05	194	38	4	4ebed7a6731b88c8359860072cbeba355a7e90ac
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	C1S CCDC80 PXDN GLI2	2.30e-05	196	38	4	525d6c8a277364e624e7cc586275f8a891436b57
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	C1S FLNA CCDC80 CDH15	2.30e-05	196	38	4	b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCell	LPS_IL1RA_TNF\|World / Treatment groups by lineage, cell group, cell type	C1S CCDC80 FOXA2 MAMDC2	2.34e-05	197	38	4	0a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 MUSK HNRNPF CDH15	2.34e-05	197	38	4	5bc11aff92da2a0aca8473f997fe7a99f3cae75d
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CCDC80 GPRC5C MAMDC2 CDH15	2.34e-05	197	38	4	2ca5ebb708935a90b12b8e98a22ae2d664ed002e
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CCDC80 GPRC5C MAMDC2 CDH15	2.39e-05	198	38	4	1f956e369e00d37835095a001db4b62a79014532
ToppCell	COVID-19-kidney-Fibroblast-2\|kidney / Disease (COVID-19 only), tissue and cell type	C1S CCDC80 PXDN GLI2	2.39e-05	198	38	4	ca26ca460856b1faaa3e83766da6abdf63af2b51
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CCDC80 GPRC5C MAMDC2 CDH15	2.39e-05	198	38	4	dc6fbad0ecdd057189f71afcdb6aca25207314a3
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	C1S CCDC80 MAMDC2 GLI2	2.39e-05	198	38	4	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	C1S CCDC80 MAMDC2 GLI2	2.39e-05	198	38	4	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	Adult-Mesenchymal\|Adult / Lineage, Cell type, age group and donor	C1S CCDC80 MAMDC2 GLI2	2.39e-05	198	38	4	26e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C1S CCDC80 PXDN MAMDC2	2.44e-05	199	38	4	30ab0750d51f168b18c434c974d24a4e70f29cc7
ToppCell	distal-mesenchymal-Alveolar_Fibroblast-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	C1S CCDC80 MAMDC2 MUSK	2.44e-05	199	38	4	28c1722deef3b8347371c7359be7c64b95780de3
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CCDC80 GPRC5C MAMDC2 CDH15	2.44e-05	199	38	4	f2ad641f36c577ff7019e88ad6b73ed7e46d8c74
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C1S FLNA CCDC80 PXDN	2.44e-05	199	38	4	36c1deac7ef0f9ebde6b2f7a63f7daa03d8c139a
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C1S FLNA CCDC80 PXDN	2.44e-05	199	38	4	3d8c76e3d05acf72a35ca755b51579fc3ae63562
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C1S CCDC80 PXDN MAMDC2	2.44e-05	199	38	4	a272c54baf8de59c0f259e6498d144a0de8d8924
ToppCell	Fibroblasts\|World / lung cells shred on cell class, cell subclass, sample id	C1S CCDC80 MAMDC2 GLI2	2.44e-05	199	38	4	e2b6752fcabd5249a166486ae6796f2c97c1fcaf
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	C1S PXDN CPT1C GLI2	2.44e-05	199	38	4	21335475bbfbad8a6943b8076a6c1c67f3eec5d3
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CCDC80 GPRC5C MAMDC2 CDH15	2.44e-05	199	38	4	7b1b3b108d817fb3b50a710c3146b30bcf9c2f6b
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	C1S CCDC80 MAMDC2 GLI2	2.48e-05	200	38	4	747c61d4e0b746278ae1f45ca4cd556c6961c76a
ToppCell	distal-2-mesenchymal-Alveolar_Fibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	C1S CCDC80 MAMDC2 MUSK	2.48e-05	200	38	4	12b705dabec1b3752a488a891eda1a5123fcdc41
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial-Astrocyte\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	MSS51 RSPH9 MAMDC2 GLI2	2.48e-05	200	38	4	b9bd6c4381c92bfc1bfff9aa778a62a41d08f1ef
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-early_osteoblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CCDC80 GPRC5C MAMDC2 CDH15	2.48e-05	200	38	4	16a7c398626b6e82b394eb3ef013bda3a788659d
ToppCell	cellseq2-Mesenchymal\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	C1S FLNA CCDC80 GPRC5C	2.48e-05	200	38	4	6b558cce0d6047c7e85f428adff80c5ca3084ea4
ToppCell	5'-Adult-SmallIntestine-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C1S FLNA CCDC80 MAMDC2	2.48e-05	200	38	4	a637281d91e95734ee4f8510b3780e0272b16fda
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Mesoderm\|6m / Sample Type, Dataset, Time_group, and Cell type.	DUSP29 MAMDC2 MUSK CDH15	2.48e-05	200	38	4	0f6851baf0cf2a8b0c95a7a585c4407c330c5f6c
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-4\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	C1S CCDC80 CPT1C GLI2	2.48e-05	200	38	4	7642a14855589b0b3f68dbdc9e4d3fc7291854f7
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CCDC80 GPRC5C MAMDC2 CDH15	2.48e-05	200	38	4	780d47f8eff630020dfae32218de495a7e9dbad6
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CCDC80 GPRC5C MAMDC2 CDH15	2.48e-05	200	38	4	28dd127787a57276253548d1f030814b1af64481
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C1S CCDC80 PXDN MUSK	2.48e-05	200	38	4	ac8a5d71acd4d401995babd233f0d3738e8ad2a5
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-4-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	C1S CCDC80 CPT1C GLI2	2.48e-05	200	38	4	444c72334df421375ae6fc69b0adfd4950d49a43
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-4\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	C1S CCDC80 CPT1C GLI2	2.48e-05	200	38	4	5826c17da67bdaba3a828792279004218d8260c8
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	C1S CCDC80 MAMDC2 GLI2	2.48e-05	200	38	4	de1d193f773f4e2927baa6fc38d29754b015c6e6
ToppCell	Substantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Rgs5_(Mural.Rgs5Acta2.Rgs5)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	C1S OTOGL MAMDC2	2.80e-05	69	38	3	a157b1582401cebd222343d94086dbea876140c2
ToppCell	Substantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Rgs5_(Mural.Rgs5Acta2.Rgs5)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	C1S OTOGL MAMDC2	2.80e-05	69	38	3	cdd42abdd072aa438830d837ee857529269a81e0
ToppCell	Thalamus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3\|Thalamus / BrainAtlas - Mouse McCarroll V32	SLC7A9 C1S OTOGL	4.87e-05	83	38	3	4017af9a4804a06d0f2cd0f285ebf1b582b751de
ToppCell	Thalamus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Car4_(Mural.Rgs5Acta2.Car4)\|Thalamus / BrainAtlas - Mouse McCarroll V32	SLC7A9 C1S OTOGL	4.87e-05	83	38	3	59fce941d45f9763a8584f3fd5b7c0738de9f592
ToppCell	Thalamus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Car4_(Mural.Rgs5Acta2.Car4)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	SLC7A9 C1S OTOGL	4.87e-05	83	38	3	ebabce70dc01fdeda7fccebc2c4a0b686cda580f
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Olfr558_(Mural.Rgs5Acta2.Olfr558)-\|Striatum / BrainAtlas - Mouse McCarroll V32	MSS51 DUSP29 OTOGL	8.75e-05	101	38	3	a05293ccd1de48ed8c7d1417f410d2c4be388c5b
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Olfr558_(Mural.Rgs5Acta2.Olfr558)\|Striatum / BrainAtlas - Mouse McCarroll V32	MSS51 DUSP29 OTOGL	8.75e-05	101	38	3	b75b000b7899399d1e6aa692d2a4c33b41a1fe18
ToppCell	Entopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	GPRC5C DUSP29 MAMDC2	1.25e-04	114	38	3	108cc5b04cc7c59310eb55dc2c44ae2b8e0b05e4
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Acinar_Adenocarcinoma-7\|TCGA-Lung / Sample_Type by Project: Shred V9	SI MAMDC2 MUSK	1.85e-04	130	38	3	0219d0d5d21df08f816569c7eb34f1bfa095d29a
ToppCell	Tracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	C1S PXDN MAMDC2	2.30e-04	140	38	3	0e1e9281de87df178ac41ed6b697b4fa09be2749
ToppCell	Control-NK\|World / Disease group and Cell class	SLC7A9 TANC2 GPRC5C	2.44e-04	143	38	3	fe08adc9472dfd4242497d6c614d0490713261da
Drug	mg 8	MGAM C1S REN	5.94e-07	11	36	3	CID000069414
Drug	Copper silicide	SI MGAM	7.28e-06	3	36	2	CID006336988
Drug	Acarbose	SI MGAM	1.46e-05	4	36	2	DB00284
Drug	nimbidiol	SI MGAM	1.46e-05	4	36	2	ctd:C496111
Drug	AC1L53LJ	SI MGAM	2.42e-05	5	36	2	CID000197521
Drug	maltoheptose	SI MGAM DPP8	3.45e-05	40	36	3	CID003037125
Drug	AC1OCFTL	SI MGAM	3.63e-05	6	36	2	CID006918743
Drug	Glucose	SI MGAM C1S CCDC80 GPRC5C REN PXDN FOXA2 NDUFB8 PSMB2	4.91e-05	1420	36	10	ctd:D005947
Drug	isomaltotetraose	SI MGAM	5.08e-05	7	36	2	CID003080783
Disease	alopecia areata (is_marker_for)	KDM4C HDAC1	5.77e-05	10	34	2	DOID:986 (is_marker_for)
Disease	Nephritis, Tubulointerstitial	SLC7A9 REN	2.67e-04	21	34	2	C0041349
Disease	BMI-adjusted fasting blood glucose measurement	FOXA2 MUSK	3.21e-04	23	34	2	EFO_0008036
Disease	Nephritis, Interstitial	SLC7A9 REN	3.50e-04	24	34	2	C0027707
Disease	1,5 anhydroglucitol measurement	SI MGAM	5.13e-04	29	34	2	EFO_0008009

Protein segments in the cluster

Peptide	Gene	Start	Entry
MRCPEDEYAGYGYHS	CCDC80	911	Q76M96
QGYESFSYGGVDPYM	RBSN	76	Q9H1K0
YGPMDDQGFYYGELG	RIMBP3B	1606	A6NNM3
YGPMDDQGFYYGELG	RIMBP3C	1606	A6NJZ7
GPKGDHTTGVGYYMY	MAMDC2	541	Q7Z304
FYHMYGGGTGLLSVY	MAMDC2	586	Q7Z304
DGDVGNYYYGQGHPM	HDAC1	16	Q13547
GDYDELGYMFPGHLG	MSS51	281	Q4VC12
SYGVHPYYMGLEEDG	MGAM	1166	O43451
PYYMGLEEDGSAHGV	MGAM	1171	O43451
NSYGVHPYYMGLEED	MGAM	2061	O43451
HPYYMGLEEDGSAHG	MGAM	2066	O43451
AGEFMITFPYGYHAG	KDM4C	266	Q9H3R0
AGGAPDHSMLYYYGQ	GLI2	1436	P10070
DYEPYPDDGMGYGDY	NDUFB8	61	O95169
EGYPFYMAMGFPGYD	POGK	166	Q9P215
QPAPGMVYDYYEKDG	OVOS2	1411	Q6IE36
SYQGDMYPTRGVGYE	GPRC5C	311	Q9NQ84
PADDHGYGVSYIFMG	CPT1C	711	Q8TCG5
TGPDYYRDMDIQYHG	DUSP29	96	Q68J44
KDLGDGVYGFEYYPM	FLNA	531	P21333
TKSGGEYPYLMEAYG	SLC7A9	91	P82251
FYDTGYTERYMGHPD	DPP8	786	Q6V1X1
CEEPYYYMENGGGGE	C1S	386	P09871
PQDFYYVAMDFGGHG	SERHL2	56	Q9H4I8
LADMYGHPCGLEYGA	CDH15	776	P55291
CEYYNEGLGEGPYML	OTOGL	1206	Q3ZCN5
DLKAYEQVMHYPGYG	FOXA2	401	Q9Y261
PQDFYYVAMDFGGHG	SERHL	56	Q9NQF3
MRPGAYSTGYGGYEE	HNRNPF	231	P52597
GEAMELYYGGHLCYG	TARS3	241	A2RTX5
GRFMGDPSYEYEHTE	RSPH9	101	Q9H1X1
YGPMDDQGFYYGELG	RIMBP3	1606	Q9UFD9
YMDTQYYGEIGIGTP	REN	81	P00797
GYDEHEGPALYYMDY	PSMB2	106	P49721
GFYADPYLYHEGRMS	KIAA1217	391	Q5T5P2
EDDYYSPHGMLANGS	TANC2	1916	Q9HCD6
DGYLYMYNLDPQEGG	WIPI2	351	Q9Y4P8
SYGFHPYYMALEEEG	SI	1146	P14410
PYYMALEEEGNAHGV	SI	1151	P14410
EVGMRTLGEYHGYDP	PXDN	1041	Q92626
YGPGSYGGMDRDYGH	ZNF326	26	Q5BKZ1
FSYGLQPYYGMAHEE	MUSK	796	O15146