Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	neurexin family protein binding	NLGN3 NLGN4X NLGN4Y	3.10e-05	16	78	3	GO:0042043
GeneOntologyBiologicalProcess	neuron cell-cell adhesion	NLGN3 NRXN3 NLGN4X NLGN4Y	3.16e-07	16	77	4	GO:0007158
GeneOntologyBiologicalProcess	postsynapse assembly	NLGN3 NRXN3 NLGN4X CARMIL3 NLGN4Y SIPA1L1	1.31e-06	93	77	6	GO:0099068
GeneOntologyBiologicalProcess	vocalization behavior	NLGN3 NRXN3 NLGN4X NLGN4Y	1.80e-06	24	77	4	GO:0071625
GeneOntologyBiologicalProcess	presynaptic membrane assembly	NLGN3 NLGN4X NLGN4Y	5.89e-06	10	77	3	GO:0097105
GeneOntologyBiologicalProcess	postsynaptic membrane assembly	NLGN3 NLGN4X NLGN4Y	8.08e-06	11	77	3	GO:0097104
GeneOntologyBiologicalProcess	social behavior	NLGN3 NRXN3 NLGN4X NLGN4Y TSC2	8.37e-06	74	77	5	GO:0035176
GeneOntologyBiologicalProcess	biological process involved in intraspecies interaction between organisms	NLGN3 NRXN3 NLGN4X NLGN4Y TSC2	9.55e-06	76	77	5	GO:0051703
GeneOntologyBiologicalProcess	presynaptic membrane organization	NLGN3 NLGN4X NLGN4Y	1.39e-05	13	77	3	GO:0097090
GeneOntologyBiologicalProcess	territorial aggressive behavior	NLGN4X NLGN4Y	4.12e-05	3	77	2	GO:0002124
GeneOntologyBiologicalProcess	peptidyl-threonine phosphorylation	CAD HIPK1 PLK1 GSK3A DYRK3	7.08e-05	115	77	5	GO:0018107
GeneOntologyBiologicalProcess	male courtship behavior	NLGN4X NLGN4Y	8.21e-05	4	77	2	GO:0008049
GeneOntologyBiologicalProcess	peptidyl-threonine modification	CAD HIPK1 PLK1 GSK3A DYRK3	1.05e-04	125	77	5	GO:0018210
GeneOntologyBiologicalProcess	axon development	HSPG2 NLGN3 ABLIM1 NRXN3 TNC ATP8A2 SIPA1L1 TSC2 NREP SEMA4G	1.33e-04	642	77	10	GO:0061564
GeneOntologyBiologicalProcess	synapse assembly	NLGN3 NRXN3 NLGN4X CARMIL3 NLGN4Y SIPA1L1 NRG2	1.52e-04	308	77	7	GO:0007416
GeneOntologyBiologicalProcess	postsynapse organization	NLGN3 NRXN3 NLGN4X CARMIL3 NLGN4Y SIPA1L1 TSC2	1.68e-04	313	77	7	GO:0099173
GeneOntologyBiologicalProcess	synapse organization	NLGN3 NRXN3 NLGN4X TNC CARMIL3 NLGN4Y SIPA1L1 NRG2 TSC2 PPFIA3	2.25e-04	685	77	10	GO:0050808
GeneOntologyBiologicalProcess	cell junction organization	NLGN3 NRXN3 NLGN4X PTPRJ TNC CARMIL3 NLGN4Y HIPK1 SIPA1L1 NRG2 TSC2 PPFIA3	2.48e-04	974	77	12	GO:0034330
GeneOntologyBiologicalProcess	neuron projection development	HSPG2 NLGN3 NEU4 ABLIM1 NRXN3 TNC ATP8A2 SIPA1L1 FSHR TSC2 NREP SEMA4G GSK3A OTOG	2.57e-04	1285	77	14	GO:0031175
GeneOntologyBiologicalProcess	cell junction assembly	NLGN3 NRXN3 NLGN4X PTPRJ CARMIL3 NLGN4Y HIPK1 SIPA1L1 NRG2	2.64e-04	569	77	9	GO:0034329
GeneOntologyBiologicalProcess	courtship behavior	NLGN4X NLGN4Y	2.85e-04	7	77	2	GO:0007619
GeneOntologyBiologicalProcess	brainstem development	NLGN4X NLGN4Y	3.80e-04	8	77	2	GO:0003360
GeneOntologyBiologicalProcess	enzyme-linked receptor protein signaling pathway	PTPRJ EGR1 LEMD3 GUCY2F SIPA1L1 FSHR NUMA1 GATA4 NRG2 TSC2 LTBP3 NREP GSK3A	4.15e-04	1186	77	13	GO:0007167
GeneOntologyBiologicalProcess	nucleus organization	LEMD3 FSHR NUMA1 PLK1 DYRK3	4.39e-04	170	77	5	GO:0006997
GeneOntologyBiologicalProcess	response to hormone	PPARGC1B CAD PTPRJ EGR1 CARD9 TNC FSHR GATA4 TSC2 TXN2 RXRG GSK3A	4.57e-04	1042	77	12	GO:0009725
GeneOntologyBiologicalProcess	multicellular organismal-level homeostasis	KAT7 PPARGC1B MAK COL11A2 ANK1 EGR1 CARD9 FSHR IREB2 LTBP3 MUC2 DYRK3	4.61e-04	1043	77	12	GO:0048871
GeneOntologyBiologicalProcess	regulation of protein localization to cell cortex	NUMA1 PLK1	4.87e-04	9	77	2	GO:1904776
GeneOntologyCellularComponent	symmetric, GABA-ergic, inhibitory synapse	NLGN3 NLGN4X NLGN4Y	2.07e-07	4	79	3	GO:0098983
GeneOntologyCellularComponent	symmetric synapse	NLGN3 NLGN4X NLGN4Y	1.45e-05	13	79	3	GO:0032280
GeneOntologyCellularComponent	asymmetric, glutamatergic, excitatory synapse	NLGN3 NLGN4X NLGN4Y	9.93e-05	24	79	3	GO:0098985
GeneOntologyCellularComponent	inhibitory synapse	NLGN3 NLGN4X NLGN4Y	2.16e-04	31	79	3	GO:0060077
GeneOntologyCellularComponent	neuronal cell body	CNTNAP3B NLGN3 CAD SIPA1L1 NUMA1 CNTNAP3 IREB2 TSC2 PAWR TXN2 GSK3A	2.93e-04	835	79	11	GO:0043025
GeneOntologyCellularComponent	GABA-ergic synapse	NLGN3 NRXN3 NLGN4X NLGN4Y NRG2	3.95e-04	164	79	5	GO:0098982
GeneOntologyCellularComponent	somatodendritic compartment	CNTNAP3B NLGN3 CAD NLGN4X NLGN4Y SIPA1L1 NUMA1 CNTNAP3 IREB2 TSC2 PAWR TXN2 GSK3A	6.55e-04	1228	79	13	GO:0036477
GeneOntologyCellularComponent	cell body	CNTNAP3B NLGN3 CAD SIPA1L1 NUMA1 CNTNAP3 IREB2 TSC2 PAWR TXN2 GSK3A	7.16e-04	929	79	11	GO:0044297
Domain	Laminin_G_2	CNTNAP3B HSPG2 COL11A2 NRXN3 CNTNAP3	6.14e-07	40	77	5	PF02210
Domain	Nlgn	NLGN3 NLGN4X NLGN4Y	6.70e-07	5	77	3	IPR000460
Domain	LamG	CNTNAP3B HSPG2 COL11A2 NRXN3 CNTNAP3	1.00e-06	44	77	5	SM00282
Domain	Laminin_G	CNTNAP3B HSPG2 COL11A2 NRXN3 CNTNAP3	4.03e-06	58	77	5	IPR001791
Domain	EGF_3	CNTNAP3B HSPG2 NRXN3 TNC CNTNAP3 NRG2 LTBP3 OTOG	5.56e-06	235	77	8	PS50026
Domain	EGF-like_dom	CNTNAP3B HSPG2 NRXN3 TNC CNTNAP3 NRG2 LTBP3 OTOG	8.49e-06	249	77	8	IPR000742
Domain	TIL	MUC5B MUC2 OTOG	1.44e-05	12	77	3	PF01826
Domain	C8	MUC5B MUC2 OTOG	1.44e-05	12	77	3	PF08742
Domain	NLGN4	NLGN4X NLGN4Y	1.68e-05	2	77	2	IPR030025
Domain	LAM_G_DOMAIN	CNTNAP3B HSPG2 NRXN3 CNTNAP3	1.77e-05	38	77	4	PS50025
Domain	Unchr_dom_Cys-rich	MUC5B MUC2 OTOG	1.87e-05	13	77	3	IPR014853
Domain	C8	MUC5B MUC2 OTOG	1.87e-05	13	77	3	SM00832
Domain	Carboxylesterase_B_CS	NLGN3 NLGN4X NLGN4Y	1.87e-05	13	77	3	IPR019819
Domain	CARBOXYLESTERASE_B_2	NLGN3 NLGN4X NLGN4Y	2.37e-05	14	77	3	PS00941
Domain	TIL_dom	MUC5B MUC2 OTOG	2.37e-05	14	77	3	IPR002919
Domain	COesterase	NLGN3 NLGN4X NLGN4Y	2.37e-05	14	77	3	PF00135
Domain	CarbesteraseB	NLGN3 NLGN4X NLGN4Y	2.37e-05	14	77	3	IPR002018
Domain	VWD	MUC5B MUC2 OTOG	3.63e-05	16	77	3	SM00216
Domain	VWF_type-D	MUC5B MUC2 OTOG	3.63e-05	16	77	3	IPR001846
Domain	VWFD	MUC5B MUC2 OTOG	3.63e-05	16	77	3	PS51233
Domain	VWD	MUC5B MUC2 OTOG	3.63e-05	16	77	3	PF00094
Domain	EGF	CNTNAP3B HSPG2 NRXN3 TNC CNTNAP3 NRG2 LTBP3	5.20e-05	235	77	7	SM00181
Domain	VWC_out	MUC5B MUC2 OTOG	6.23e-05	19	77	3	SM00215
Domain	EGF_1	CNTNAP3B HSPG2 NRXN3 TNC CNTNAP3 NRG2 LTBP3	8.68e-05	255	77	7	PS00022
Domain	CT	MUC5B MUC2 OTOG	9.81e-05	22	77	3	SM00041
Domain	EGF_2	CNTNAP3B HSPG2 NRXN3 TNC CNTNAP3 NRG2 LTBP3	1.10e-04	265	77	7	PS01186
Domain	Cys_knot_C	MUC5B MUC2 OTOG	1.45e-04	25	77	3	IPR006207
Domain	CTCK_2	MUC5B MUC2 OTOG	1.45e-04	25	77	3	PS01225
Domain	EGF	HSPG2 NRXN3 TNC CNTNAP3 NRG2	1.73e-04	126	77	5	PF00008
Domain	WxxW_domain	MUC5B MUC2	2.49e-04	6	77	2	IPR025155
Domain	Mucin2_WxxW	MUC5B MUC2	2.49e-04	6	77	2	PF13330
Domain	FIBRINOGEN_C_1	CNTNAP3B TNC CNTNAP3	3.07e-04	32	77	3	PS00514
Domain	Fibrinogen_a/b/g_C_dom	CNTNAP3B TNC CNTNAP3	3.07e-04	32	77	3	IPR002181
Domain	FIBRINOGEN_C_2	CNTNAP3B TNC CNTNAP3	3.07e-04	32	77	3	PS51406
Domain	-	HSPG2 COL11A2 NRXN3 CNTNAP3	6.40e-04	95	77	4	2.60.120.200
Domain	VWF_dom	MUC5B MUC2 OTOG	6.89e-04	42	77	3	IPR001007
Domain	EGF-like_CS	HSPG2 NRXN3 TNC CNTNAP3 NRG2 LTBP3	7.27e-04	261	77	6	IPR013032
Domain	ZU5	ANK1 PIDD1	7.39e-04	10	77	2	PS51145
Domain	Rap_GAP	SIPA1L1 TSC2	7.39e-04	10	77	2	PF02145
Domain	Rap_GAP_dom	SIPA1L1 TSC2	9.01e-04	11	77	2	IPR000331
Domain	RAPGAP	SIPA1L1 TSC2	9.01e-04	11	77	2	PS50085
Domain	ZU5	ANK1 PIDD1	1.08e-03	12	77	2	PF00791
Domain	ZU5_dom	ANK1 PIDD1	1.08e-03	12	77	2	IPR000906
Domain	ConA-like_dom	CNTNAP3B HSPG2 COL11A2 NRXN3 CNTNAP3	2.11e-03	219	77	5	IPR013320
Domain	CTCK_1	MUC5B MUC2	2.46e-03	18	77	2	PS01185
Domain	FA58C	CNTNAP3B CNTNAP3	3.35e-03	21	77	2	SM00231
Domain	FA58C_3	CNTNAP3B CNTNAP3	3.35e-03	21	77	2	PS50022
Domain	FA58C_1	CNTNAP3B CNTNAP3	3.35e-03	21	77	2	PS01285
Domain	FA58C_2	CNTNAP3B CNTNAP3	3.35e-03	21	77	2	PS01286
Pathway	REACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES	NLGN3 NRXN3 NLGN4X NLGN4Y SIPA1L1 PPFIA3	1.61e-06	87	59	6	M27617
Pathway	REACTOME_NEUREXINS_AND_NEUROLIGINS	NLGN3 NRXN3 NLGN4X NLGN4Y SIPA1L1	3.50e-06	56	59	5	M27616
Pathway	REACTOME_PROTEIN_PROTEIN_INTERACTIONS_AT_SYNAPSES	NLGN3 NRXN3 NLGN4X NLGN4Y PPFIA3	8.55e-06	67	59	5	MM15327
Pathway	REACTOME_NEUREXINS_AND_NEUROLIGINS	NLGN3 NRXN3 NLGN4X NLGN4Y	9.12e-06	32	59	4	MM15326
Pubmed	Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways.	NLGN3 NRXN3 NLGN4X NLGN4Y	1.71e-09	8	79	4	30871858
Pubmed	SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins.	NLGN3 NRXN3 NLGN4X NLGN4Y	8.04e-09	11	79	4	32973045
Pubmed	Evolution of the Autism-Associated Neuroligin-4 Gene Reveals Broad Erosion of Pseudoautosomal Regions in Rodents.	NLGN3 NLGN4X NLGN4Y	1.13e-08	3	79	3	32011705
Pubmed	Analysis of the neuroligin 4Y gene in patients with autism.	NLGN3 NLGN4X NLGN4Y	1.13e-08	3	79	3	18628683
Pubmed	Advancing the understanding of autism disease mechanisms through genetics.	NLGN3 NLGN4X NLGN4Y TSC2	1.74e-08	13	79	4	27050589
Pubmed	Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism.	NLGN3 NLGN4X NLGN4Y	4.50e-08	4	79	3	12669065
Pubmed	Homodimerization and isoform-specific heterodimerization of neuroligins.	NLGN3 NLGN4X NLGN4Y	4.50e-08	4	79	3	22671294
Pubmed	Ultrasonic vocalizations in mouse models for speech and socio-cognitive disorders: insights into the evolution of vocal communication.	NLGN3 NLGN4X NLGN4Y	4.50e-08	4	79	3	20579107
Pubmed	Analysis of four neuroligin genes as candidates for autism.	NLGN3 NLGN4X NLGN4Y	4.50e-08	4	79	3	16077734
Pubmed	Neuroligins 3 and 4X interact with syntrophin-gamma2, and the interactions are affected by autism-related mutations.	NLGN3 NLGN4X NLGN4Y	4.50e-08	4	79	3	17292328
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	ABLIM1 ANK1 LEMD3 TNC SIPA1L1 TSC2 PPFIA3 SRRM2	5.83e-08	231	79	8	16452087
Pubmed	Neuroligins and neurexins link synaptic function to cognitive disease.	NRXN3 NLGN4X NLGN4Y	1.12e-07	5	79	3	18923512
Pubmed	Synapse formation: if it looks like a duck and quacks like a duck ...	NLGN3 NLGN4X NLGN4Y	1.12e-07	5	79	3	10996085
Pubmed	Multiple N-linked glycosylation sites critically modulate the synaptic abundance of neuroligin isoforms.	NLGN3 NLGN4X NLGN4Y	1.12e-07	5	79	3	37865312
Pubmed	The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?	NLGN3 NLGN4X NLGN4Y	2.24e-07	6	79	3	21838267
Pubmed	Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.	NLGN3 NLGN4X NLGN4Y	2.24e-07	6	79	3	29724786
Pubmed	Using mouse models of autism spectrum disorders to study the neurotoxicology of gene-environment interactions.	NLGN3 NLGN4X NLGN4Y	9.38e-07	9	79	3	23010509
Pubmed	Behavioral phenotypes of genetic mouse models of autism.	NLGN3 NLGN4X NLGN4Y	1.84e-06	11	79	3	26403076
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ABLIM1 SEC24A SIPA1L1 TSC2 ITPRID2 PLK1 SRRM2 PCDH7 GSK3A DOP1A OTOG	3.92e-06	861	79	11	36931259
Pubmed	Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism.	NLGN3 NLGN4X NLGN4Y	5.03e-06	15	79	3	18227507
Pubmed	Association Analysis of Noncoding Variants in Neuroligins 3 and 4X Genes with Autism Spectrum Disorder in an Italian Cohort.	NLGN3 NLGN4X	5.09e-06	2	79	2	27782075
Pubmed	The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.	CNTNAP3B CNTNAP3	5.09e-06	2	79	2	31150793
Pubmed	Not all neuroligin 3 and 4X missense variants lead to significant functional inactivation.	NLGN3 NLGN4X	5.09e-06	2	79	2	28948087
Pubmed	Novel splice isoforms for NLGN3 and NLGN4 with possible implications in autism.	NLGN3 NLGN4X	5.09e-06	2	79	2	16648374
Pubmed	A substitution involving the NLGN4 gene associated with autistic behavior in the Greek population.	NLGN3 NLGN4X	5.09e-06	2	79	2	19645625
Pubmed	Unusually rapid evolution of Neuroligin-4 in mice.	NLGN4X NLGN4Y	5.09e-06	2	79	2	18434543
Pubmed	Mutation screening of X-chromosomal neuroligin genes: no mutations in 196 autism probands.	NLGN3 NLGN4X	5.09e-06	2	79	2	15274046
Pubmed	Genetic Complexity of Mitral Valve Prolapse Revealed by Clinical and Genetic Evaluation of a Large Family.	FLYWCH1 PTPRJ	5.09e-06	2	79	2	29762926
Pubmed	Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism.	NLGN4X NLGN4Y	5.09e-06	2	79	2	23183221
Pubmed	Juvenile manifestation of ultrasound communication deficits in the neuroligin-4 null mutant mouse model of autism.	NLGN4X NLGN4Y	5.09e-06	2	79	2	24855039
Pubmed	Analysis of the genes encoding neuroligins NLGN3 and NLGN4 in Bulgarian patients with autism.	NLGN3 NLGN4X	5.09e-06	2	79	2	23431752
Pubmed	The murine Muc2 mucin gene is transcriptionally regulated by the zinc-finger GATA-4 transcription factor in intestinal cells.	GATA4 MUC2	5.09e-06	2	79	2	15541382
Pubmed	Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder.	NLGN4X NLGN4Y	5.09e-06	2	79	2	37001827
Pubmed	Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.	CNTNAP3B CNTNAP3	5.09e-06	2	79	2	26807827
Pubmed	Prenatal exposure to valproic acid leads to reduced expression of synaptic adhesion molecule neuroligin 3 in mice.	NLGN3 NRXN3	5.09e-06	2	79	2	19607885
Pubmed	Increased Network Inhibition in the Dentate Gyrus of Adult Neuroligin-4 Knock-Out Mice.	NLGN4X NLGN4Y	5.09e-06	2	79	2	37080762
Pubmed	Absence of coding mutations in the X-linked genes neuroligin 3 and neuroligin 4 in individuals with autism from the IMGSAC collection.	NLGN3 NLGN4X	5.09e-06	2	79	2	16508939
Pubmed	Autism Related Neuroligin-4 Knockout Impairs Intracortical Processing but not Sensory Inputs in Mouse Barrel Cortex.	NLGN4X NLGN4Y	5.09e-06	2	79	2	29106499
Pubmed	NLGN3/NLGN4 gene mutations are not responsible for autism in the Quebec population.	NLGN3 NLGN4X	5.09e-06	2	79	2	15389766
Pubmed	Perturbed Hippocampal Synaptic Inhibition and γ-Oscillations in a Neuroligin-4 Knockout Mouse Model of Autism.	NLGN4X NLGN4Y	5.09e-06	2	79	2	26456829
Pubmed	Nlgn4 knockout induces network hypo-excitability in juvenile mouse somatosensory cortex in vitro.	NLGN4X NLGN4Y	5.09e-06	2	79	2	24104404
Pubmed	The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule.	HSPG2 RHOBTB3	5.09e-06	2	79	2	1744087
Pubmed	A Cluster of Autism-Associated Variants on X-Linked NLGN4X Functionally Resemble NLGN4Y.	NLGN4X NLGN4Y	5.09e-06	2	79	2	32243781
Pubmed	Absence of deficits in social behaviors and ultrasonic vocalizations in later generations of mice lacking neuroligin4.	NLGN4X NLGN4Y	5.09e-06	2	79	2	22989184
Pubmed	[Interleukin-1beta induces MUC2/MUC5B gene expression in human nasal epithelial cells].	MUC5B MUC2	5.09e-06	2	79	2	20873538
Pubmed	Role for Plk1 phosphorylation of Hbo1 in regulation of replication licensing.	KAT7 PLK1	5.09e-06	2	79	2	18250300
Pubmed	Variations analysis of NLGN3 and NLGN4X gene in Chinese autism patients.	NLGN3 NLGN4X	5.09e-06	2	79	2	24570023
Pubmed	No evidence for involvement of genetic variants in the X-linked neuroligin genes NLGN3 and NLGN4X in probands with autism spectrum disorder on high functioning level.	NLGN3 NLGN4X	5.09e-06	2	79	2	18189281
Pubmed	Aberrant O-glycosylation contributes to tumorigenesis in human colorectal cancer.	TNC MUC2	5.09e-06	2	79	2	29999571
Pubmed	Disorder-associated mutations lead to functional inactivation of neuroligins.	NLGN3 NLGN4X	5.09e-06	2	79	2	15150161
Pubmed	Analysis of the neuroligin 3 and 4 genes in autism and other neuropsychiatric patients.	NLGN3 NLGN4X	5.09e-06	2	79	2	15622415
Pubmed	Mutation screening in the Greek population and evaluation of NLGN3 and NLGN4X genes causal factors for autism.	NLGN3 NLGN4X	5.09e-06	2	79	2	23851596
Pubmed	Pharmacological inhibition of Polo-like kinase 1 (PLK1) by BI-2536 decreases the viability and survival of hamartin and tuberin deficient cells via induction of apoptosis and attenuation of autophagy.	TSC2 PLK1	1.53e-05	3	79	2	25565629
Pubmed	Significance of neurexin and neuroligin polymorphisms in regulating risk of Hirschsprung's disease.	NLGN3 NLGN4X	1.53e-05	3	79	2	29622757
Pubmed	Hamartin, the tuberous sclerosis complex 1 gene product, interacts with polo-like kinase 1 in a phosphorylation-dependent manner.	TSC2 PLK1	1.53e-05	3	79	2	16339216
Pubmed	Plk1 phosphorylation of orc2 and hbo1 contributes to gemcitabine resistance in pancreatic cancer.	KAT7 PLK1	1.53e-05	3	79	2	23188630
Pubmed	Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina.	NLGN4X NLGN4Y	1.53e-05	3	79	2	21282647
Pubmed	Mucin gene polymorphisms in otitis media patients.	MUC5B MUC2	1.53e-05	3	79	2	19718741
Pubmed	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.	DCHS2 ABLIM1 PPARGC1B CARD9 ATXN7L1 SIPA1L1 IREB2 TSC2 NREP PCDH7	1.57e-05	814	79	10	23251661
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	CAD PTPRJ LEMD3 SEC24A ITPRID2 HERC2 PPFIA3 PLK1 SRRM2 PCDH7 GSK3A	2.48e-05	1049	79	11	27880917
Pubmed	DSCAM Deficiency Leads to Premature Spine Maturation and Autism-like Behaviors.	NLGN3 NLGN4X NLGN4Y	2.82e-05	26	79	3	34848499
Pubmed	The protein interaction landscape of the human CMGC kinase group.	MAK TROAP HIPK1 SIPA1L1 MED14 HERC2 SRRM2 GSK3A DYRK3	2.86e-05	695	79	9	23602568
Pubmed	Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.	MUC5B MUC2	3.05e-05	4	79	2	25638393
Pubmed	Opposing action of nuclear factor κB and Polo-like kinases determines a homeostatic end point for excitatory synaptic adaptation.	SIPA1L1 PLK1	3.05e-05	4	79	2	24133254
Pubmed	Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.	MUC5B MUC2	3.05e-05	4	79	2	17471237
Pubmed	Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.	MUC5B MUC2	3.05e-05	4	79	2	22269464
Pubmed	The mouse secreted gel-forming mucin gene cluster.	MUC5B MUC2	3.05e-05	4	79	2	14984930
Pubmed	Lack of association between NLGN3, NLGN4, SHANK2 and SHANK3 gene variants and autism spectrum disorder in a Chinese population.	NLGN3 NLGN4X	3.05e-05	4	79	2	23468870
Pubmed	Insulin inhibits lipolysis in adipocytes via the evolutionarily conserved mTORC1-Egr1-ATGL-mediated pathway.	EGR1 TSC2	3.05e-05	4	79	2	23858058
Pubmed	Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.	MUC5B MUC2	3.05e-05	4	79	2	29869461
Pubmed	A novel anesthesia regime enables neurofunctional studies and imaging genetics across mouse strains.	NLGN3 TSC2	3.05e-05	4	79	2	27080031
Pubmed	Polymorphisms in MUC1, MUC2, MUC5B and MUC6 genes are not associated with the risk of chronic atrophic gastritis.	MUC5B MUC2	3.05e-05	4	79	2	21596555
Pubmed	Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.	MUC5B MUC2	3.05e-05	4	79	2	23807779
Pubmed	Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.	MUC5B MUC2	3.05e-05	4	79	2	12676567
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	NLGN3 ABLIM1 NLGN4X NLGN4Y SIPA1L1 PCDH7	4.47e-05	281	79	6	28706196
Pubmed	Wnt/β-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells.	TNC GATA4 PCDH7	4.84e-05	31	79	3	22711842
Pubmed	Polymorphism of human mucin genes in chest disease: possible significance of MUC2.	MUC5B MUC2	5.07e-05	5	79	2	11062147
Pubmed	Coordination of PGC-1beta and iron uptake in mitochondrial biogenesis and osteoclast activation.	PPARGC1B IREB2	5.07e-05	5	79	2	19252502
Pubmed	Comprehensive glycomics comparison between colon cancer cell cultures and tumours: implications for biomarker studies.	MUC5B MUC2	5.07e-05	5	79	2	24840470
Pubmed	Spatial and temporal changes in chondroitin sulfate distribution in the sclerotome play an essential role in the formation of migration patterns of mouse neural crest cells.	HSPG2 TNC	5.07e-05	5	79	2	9915576
Pubmed	Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins.	NLGN3 NLGN4X	5.07e-05	5	79	2	15620359
Pubmed	Neuroligin-induced presynaptic differentiation through SLM2-mediated splicing modifications of neurexin in cerebellar cultures.	NLGN3 NRXN3	5.07e-05	5	79	2	28939043
Pubmed	Differential expression of MUC genes in endometrial and cervical tissues and tumors.	MUC5B MUC2	5.07e-05	5	79	2	16188033
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ABLIM1 SIPA1L1 NUMA1 MED14 SAC3D1 ITPRID2 SRRM2 PCDH7 GSK3A	6.55e-05	774	79	9	15302935
Pubmed	Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.	MUC5B MUC2	7.60e-05	6	79	2	19110483
Pubmed	HERC2 targets the iron regulator FBXL5 for degradation and modulates iron metabolism.	IREB2 HERC2	7.60e-05	6	79	2	24778179
Pubmed	In trans neuregulin3-Caspr3 interaction controls DA axonal bassoon cluster development.	CNTNAP3B CNTNAP3	7.60e-05	6	79	2	34143959
Pubmed	Structures, alternative splicing, and neurexin binding of multiple neuroligins.	NLGN3 NRXN3	7.60e-05	6	79	2	8576240
Pubmed	Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.	ABLIM1 CAD SIPA1L1 NUMA1 PAWR ITPRID2 HERC2 SRRM2	8.94e-05	626	79	8	33644029
Pubmed	Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.	ABLIM1 HIPK1 NUMA1 PCDH7 GSK3A DYRK3	1.03e-04	327	79	6	15592455
Pubmed	Cardiac expression of ms1/STARS, a novel gene involved in cardiac development and disease, is regulated by GATA4.	ANK1 GATA4	1.06e-04	7	79	2	22431517
Pubmed	Comprehensive Characterization of Tissues Derived from Animals at Different Regenerative Stages: A Comparative Analysis between Fetal and Adult Mouse Skin.	HSPG2 TNC	1.06e-04	7	79	2	37174615
Pubmed	Molecular mechanisms of cell and tissue interactions during early tooth development.	EGR1 TNC	1.06e-04	7	79	2	8769660
Pubmed	N-myc regulates growth and fiber cell differentiation in lens development.	NUMA1 HSF4	1.06e-04	7	79	2	28716713
Pubmed	Wnt signaling has opposing roles in the developing and the adult brain that are modulated by Hipk1.	HIPK1 GATA4	1.41e-04	8	79	2	22095214
Pubmed	Mice develop normally without tenascin.	HSPG2 TNC	1.41e-04	8	79	2	1383086
Pubmed	sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1.	NUMA1 PLK1	1.41e-04	8	79	2	18331714
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	ABLIM1 TNC HIPK1 SIPA1L1 NRG2 SRRM2	1.42e-04	347	79	6	17114649
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	THAP4 DCHS2 ABLIM1 HIPK1 RHOBTB3 SIPA1L1 TSC2 LTBP3 HERC2 RXRG GSK3A	1.52e-04	1285	79	11	35914814
Pubmed	Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method.	MAK CAD NUMA1 RXRG	1.66e-04	120	79	4	21697133
GeneFamily	CD molecules\|Mucins	MUC5B MUC2	1.13e-03	21	43	2	648
Coexpression	GSE11818_WT_VS_DICER_KO_TREG_UP	HSPG2 CRACR2A CARMIL3 SIPA1L1 DLEC1 ARSI	5.36e-06	146	79	6	M412
Coexpression	CYCLIN_D1_KE_.V1_UP	HSPG2 ABLIM1 TROAP FSHR TSC2 HSF4	2.26e-05	188	79	6	M2648
Coexpression	GSE22886_NAIVE_CD4_TCELL_VS_MEMORY_TCELL_UP	THAP4 HSPG2 CARD9 SIPA1L1 NUMA1 SEMA4G	2.70e-05	194	79	6	M4411
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HSPG2 CENPF TROAP PIDD1 PPFIA3 PLK1	8.23e-07	180	79	6	40d4838a0ccb10d5e49266bc8a0037d27b75ccc2
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B ANK1 TNC CNTNAP3 ALPK3 PAWR	8.50e-07	181	79	6	af92b8b7f455210dab502ef6964f3a0162180759
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CNTNAP3B HSPG2 ABLIM1 CNTNAP3 GATA4 PCDH7	1.09e-06	189	79	6	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	NRXN3 ANK1 CNTNAP3 HSF4 SEMA4G	1.00e-05	161	79	5	b81b346309f3facbfbebd91cae4c5b33c7bd24ef
ToppCell	Frontal_cortex-Neuronal-Inhibitory\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	NRXN3 ANK1 CARMIL3 CNTNAP3 SEMA4G	1.27e-05	169	79	5	78eb70dd916724e476eabccf18fb7fcec4210308
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-granulocyte-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAK SAMD9L TROAP ALPK3 PLK1	1.34e-05	171	79	5	41932c9e70829ee3d55ca5fdb74d290fc8229416
ToppCell	Adult-Epithelial-lung_goblet_cell-D231\|Adult / Lineage, Cell type, age group and donor	DCHS2 NRXN3 CRACR2A MUC5B PCDH7	1.46e-05	174	79	5	7d2f802f493f19a068e097b2909a9000e2160266
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NLGN4X CENPF TROAP TNC PLK1	1.50e-05	175	79	5	cc596907ea1a64ab7b5a8c7d4ad12e6ee59bfed9
ToppCell	10x_5'_v1-Neoplastic-Stem-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NLGN4X CENPF TROAP TNC PLK1	1.50e-05	175	79	5	a8400e7e47379901dcab5f2e364c3ff17765b4b9
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NRXN3 CENPF TROAP PIDD1 PLK1	1.50e-05	175	79	5	d43ae33a6256606ce848247cad32d74f21b38988
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN3 ANK1 LEMD3 FSHR NREP	1.50e-05	175	79	5	65571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NLGN4X CENPF TROAP TNC PLK1	1.50e-05	175	79	5	8a3abf40146ae3459d97cdf865c1c8f6b92ac639
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NLGN4X CENPF TROAP TNC PLK1	1.50e-05	175	79	5	378d2b79edac91fc74eee0fb42bb29dd9b07c36f
ToppCell	wk_20-22-Hematologic-Meg-ery-Cycling_definitive_erythroblast\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ANK1 CENPF TROAP MYO18B PLK1	1.54e-05	176	79	5	98814f0a67411b2f7b25dc489b2aadb77f45a853
ToppCell	PND03-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF TROAP ATP8A2 PLK1 DYRK3	1.54e-05	176	79	5	1f8d5a48fedbb4c86272c9b5a0f1ef573350357b
ToppCell	Dividing_Macrophages-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	NEU4 CENPF TROAP SAC3D1 PLK1	1.63e-05	178	79	5	6557688c6790a5bcc3b9aea5b8789cf9506b3c54
ToppCell	Adult-Epithelial-lung_goblet_cell\|Adult / Lineage, Cell type, age group and donor	DCHS2 NRXN3 CRACR2A MUC5B PCDH7	1.67e-05	179	79	5	1fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCell	severe-Others-CD34+_GATA2+_cells\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	HSPG2 PGAP4 PAWR NREP DYRK3	1.67e-05	179	79	5	dd789a1b7327d6f9ed5272f3eb54bd43f7ae8d78
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NLGN4X TNC ATP8A2 NREP DYRK3	1.67e-05	179	79	5	a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell	3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_Myeloid\|bone_marrow / Manually curated celltypes from each tissue	EGR1 CENPF TROAP NREP PLK1	1.81e-05	182	79	5	6745d464c3ff289726aa8164e9a43f407f8e4380
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B ANK1 CNTNAP3 PAWR MUC2	1.81e-05	182	79	5	08aff7112c9dac0ef5540300516a604782b21169
ToppCell	Globus_pallidus-Neuronal-Inhibitory\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ANK1 MROH1 FLYWCH1 HSF4 SEMA4G	1.81e-05	182	79	5	04ccfa951eaa31fed6d140edb6c702d49363c5fa
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NRXN3 NLGN4X TNC PCDH7 ARSI	1.86e-05	183	79	5	61a73de857f4ae02dcba3af348f436f602b28ff2
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B ANK1 TNC CNTNAP3 ALPK3	1.91e-05	184	79	5	7d41784eac0935e77d6bc701f20c693adf998730
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABLIM1 GATA4 ALPK3 MYO18B PCDH7	1.96e-05	185	79	5	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RHOBTB3 GATA4 PRRG3 PLK1 ARSI	2.07e-05	187	79	5	fa8f221b4c2df61eadaa9c77e4cf45848b00330b
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 COL11A2 NRXN3 TNC ATP8A2	2.23e-05	190	79	5	f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 COL11A2 NRXN3 TNC ATP8A2	2.23e-05	190	79	5	a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 COL11A2 NRXN3 TNC ATP8A2	2.23e-05	190	79	5	57c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B ANK1 RHOBTB3 CNTNAP3 PAWR	2.29e-05	191	79	5	782bc7946417549ffd39e5b596db659436fa01ba
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	CNTNAP3B HSPG2 SIPA1L1 CNTNAP3 PCDH7	2.34e-05	192	79	5	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	ABLIM1 GATA4 ALPK3 MYO18B PCDH7	2.40e-05	193	79	5	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF TROAP TNC NREP PLK1	2.40e-05	193	79	5	a332dfdcc48c405020014e644aa4d14fda98cc86
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	ABLIM1 GATA4 ALPK3 MYO18B PCDH7	2.52e-05	195	79	5	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	facs-Bladder-nan-3m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABLIM1 EGR1 RHOBTB3 LTBP3 PCDH7	2.59e-05	196	79	5	44f5b1b474399c9316729155f2ea95a82ca66e30
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NLGN4X EGR1 TNC RHOBTB3 PAWR	2.59e-05	196	79	5	45d1c0a962c4221c17393ee5566961d1deebf442
ToppCell	facs-Bladder-nan-3m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABLIM1 EGR1 RHOBTB3 LTBP3 PCDH7	2.59e-05	196	79	5	c0e90d964baa2eb4fbd18a52379ccec5d3bf59a8
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF TROAP TNC NREP PLK1	2.65e-05	197	79	5	29b0a5927f80455eef7b793feabef69fba1a3df1
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_basal-Dividing_Basal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	COL11A2 CENPF TROAP SAC3D1 PLK1	2.65e-05	197	79	5	0a6754a5109bec0d0de42adbfdf4db43ff60c3d2
ToppCell	LPS_only-Endothelial-Endothelial-FOXM1\|LPS_only / Treatment groups by lineage, cell group, cell type	KAT7 HSPG2 CENPF TROAP PLK1	2.65e-05	197	79	5	038fd92750257d43d5e980fd06d77742b543f11a
ToppCell	Caecum-B_cell-B_cell_cycling\|Caecum / Region, Cell class and subclass	NLGN3 CENPF TROAP SAC3D1 PLK1	2.72e-05	198	79	5	61294fe99a5641ad359796022c3d038470076b3c
ToppCell	Caecum-B_cell-B_cell_cycling\|B_cell / Region, Cell class and subclass	NLGN3 CENPF TROAP SAC3D1 PLK1	2.72e-05	198	79	5	d2def132f3efe9305a5501a96ec82efb1f02c3f7
ToppCell	Caecum-(2)_B_cell-(24)_B_cell_cycling\|Caecum / shred on region, Cell_type, and subtype	NLGN3 CENPF TROAP SAC3D1 PLK1	2.72e-05	198	79	5	568d47770cd20c6569ca84ea1eafde367642d68b
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EGR1 TNC NRG2 PAWR PCDH7	2.72e-05	198	79	5	fc00cb25cdc6c31b7f9d397bc9f9a8f4e9708003
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DCHS2 NRXN3 CRACR2A MUC5B PCDH7	2.72e-05	198	79	5	fab3135f03cf23a9f04f0eed543a9dc181f39f5f
ToppCell	(2)_B_cell-(24)_B_cell_cycling\|(2)_B_cell / shred on Cell_type and subtype	NLGN3 CENPF TROAP SAC3D1 PLK1	2.78e-05	199	79	5	d5a9a8a71c4de8cbcef947943f60838731bc640b
ToppCell	B_cell_maturation-pre-B\|B_cell_maturation / Lineage and Cell class	CENPF TROAP SAC3D1 NREP PLK1	2.78e-05	199	79	5	4bf6a656de04d92103cbe743cd07afd9d125c654
ToppCell	droplet-Trachea\|droplet / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 COL11A2 EGR1 LTBP3 NREP	2.78e-05	199	79	5	1c7d30765ddb2291967da5d15664c6238c680c1d
ToppCell	droplet-Trachea\|droplet / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 COL11A2 EGR1 LTBP3 NREP	2.78e-05	199	79	5	b9038a1ccf3ef3123e2e39afbe6213c363437443
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Dividing_Basal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	MROH1 CENPF TROAP SAC3D1 MUC5B	2.78e-05	199	79	5	f0c289523957258d16135c04679db379d43d28d9
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SULF1--L4-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B ANK1 RHOBTB3 CNTNAP3 PAWR	2.85e-05	200	79	5	4a426ef88376d8bb2b9dc50aa06e7b9fc50ecc9c
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DCHS2 NRXN3 CRACR2A MUC5B PCDH7	2.85e-05	200	79	5	b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-HPGD-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B NRXN3 ANK1 CNTNAP3 PAWR	2.85e-05	200	79	5	1ec2f322f936d2501330c53bb7c9390216c50cd1
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-HPGD--L3-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B NRXN3 ANK1 CNTNAP3 PAWR	2.85e-05	200	79	5	e250b2e45ef869f81cc40cc41f53d1e54e7848aa
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)-FRZB--L2-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B ANK1 RHOBTB3 CNTNAP3 PAWR	2.85e-05	200	79	5	5ec469267747dce3601c1d8ad01af89fa5b29acc
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)-FRZB\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B ANK1 RHOBTB3 CNTNAP3 PAWR	2.85e-05	200	79	5	e79d93d55b25804f2608185168da472301b6ebca
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SULF1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B ANK1 RHOBTB3 CNTNAP3 PAWR	2.85e-05	200	79	5	fbeee1c16ac0a7fe28d90491c8b079f21ce80bdc
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SULF1-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B ANK1 RHOBTB3 CNTNAP3 PAWR	2.85e-05	200	79	5	c6eda342ea0cb37d71d89dbb8d11e819e0745172
ToppCell	B_cell_maturation-pre-B\|World / Lineage and Cell class	CENPF TROAP SAC3D1 NREP PLK1	2.85e-05	200	79	5	acb9ad7e3c05ec38e9700fb27b6eed8eaa565689
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-HPGD\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B NRXN3 ANK1 CNTNAP3 PAWR	2.85e-05	200	79	5	dea96adbd9a77fe50ff397d4bdeb4dc8f50de3b7
ToppCell	Neuronal-Inhibitory-iB\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B NRXN3 ANK1 CNTNAP3 PAWR	2.85e-05	200	79	5	45ddc5ef2caa87ada88327b63ba9b150a6bb3aa5
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)-FRZB-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B ANK1 RHOBTB3 CNTNAP3 PAWR	2.85e-05	200	79	5	320d5a3a1e7da2fa8f1a164e29e180ec8ac9889c
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Rostral-�migratory_stream-�(RMS)_(Tuba1c))\|Striatum / BrainAtlas - Mouse McCarroll V32	TROAP MYO18B PLK1 ARSI	3.16e-05	101	79	4	0b32e6071f05dbe808e51e18c3a3f8221f438f83
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	NEU4 COL11A2 GUCY2F MUC5B	4.41e-05	110	79	4	b9c8014fd2820e5ea28a7e02fd24227b99e71eb3
ToppCell	Posterior_cortex-Macroglia-POLYDENDROCYTE-P2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	NEU4 COL11A2 GUCY2F MUC5B	4.41e-05	110	79	4	ee45592e936d32881c0f3429c21360670e5b3ce3
ToppCell	primary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Ccnb1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NEU4 CENPF TROAP PLK1	8.20e-05	129	79	4	ff74d159034a09f7b174da18bfb9a26936252b4c
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WDR64 CENPF TROAP ARSI	8.97e-05	132	79	4	f1b448efccbf87caa86d1a794c43a230a4b0758e
ToppCell	Striatum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Striatum / BrainAtlas - Mouse McCarroll V32	ANK1 CRACR2A HSF4 SEMA4G	9.23e-05	133	79	4	d5326a6ccada5ae6d3e8f7d4a858c90050e23c5b
ToppCell	LPS_only-Endothelial-Endothelial-FOXM1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KAT7 CENPF TROAP PLK1	9.51e-05	134	79	4	4d8f7ddad02fe76a614771e115ebb8e04623ba85
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Car3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SAMD9L CRACR2A CNTNAP3 TGM6	9.51e-05	134	79	4	4ef5f395e321cf04e56560be2502a8aa157682f4
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WDR64 NRXN3 GATA4 ALPK3	1.26e-04	144	79	4	e9d62f202f0fa8747961036ef0eafed91fe8a42f
ToppCell	Dividing_Macrophages-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	WDR64 CENPF TROAP PLK1	1.39e-04	148	79	4	66b51aa6690bf8fbc90fa5a6f86191703e2d5046
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 ABLIM1 CNTNAP3 OTOG	1.88e-04	160	79	4	33050dc646762dc7e9dcc4a12c618e1ba1ce5a4d
ToppCell	367C-Myeloid-Dendritic-cDC_proliferating_2\|367C / Donor, Lineage, Cell class and subclass (all cells)	PPARGC1B CENPF TROAP PLK1	2.07e-04	164	79	4	0662cd9d21608efacc336e0a582859f3b9a4951d
ToppCell	Adult-Epithelial-lung_goblet_cell-D175\|Adult / Lineage, Cell type, age group and donor	CRACR2A PGAP4 MUC5B PCDH7	2.07e-04	164	79	4	6e6aedb61f8e195d52e028fdda750a29bb14e57e
ToppCell	367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	DCHS2 TROAP SAC3D1 PLK1	2.07e-04	164	79	4	fb18b863152fb3109e2224c791c84c6371680a4e
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Lymphocytic-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPARGC1B ATP8A2 NRG2 DYRK3	2.12e-04	165	79	4	475905d608fac628960188ae4a18010b8097417e
ToppCell	wk_15-18-Hematologic-Meg-ery-HMOX1+_primitive_erythroblast\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ANK1 MYO18B CYB5R1 DYRK3	2.12e-04	165	79	4	a040d18e4ba6da266440ad0b79990918770bfa7d
ToppCell	LV-16._Neuronal\|World / Chamber and Cluster_Paper	NRXN3 NLGN4X PTPRJ RXRG	2.12e-04	165	79	4	6ed52cb756d21addf46c7f6c457458b01339fe04
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WDR64 NRXN3 NLGN4X RXRG	2.16e-04	166	79	4	f742d15b02a6f651bbd00f53e3d871f40d05a03d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WDR64 NRXN3 NLGN4X RXRG	2.16e-04	166	79	4	0f013bb5fdb72e88c2fc73d60cd01551a2db6341
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WDR64 NRXN3 NLGN4X RXRG	2.16e-04	166	79	4	e941df9a1091164edde3def8fc7d410186b2bd88
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DCHS2 BRD3OS ATP8A2 GSK3A	2.16e-04	166	79	4	c11dcf9705b85ac3da6ae86358f5ffd64ae8327e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WDR64 NRXN3 NLGN4X RXRG	2.16e-04	166	79	4	aeda46bea5d8463c24a83b98b9ed92d962d733e5
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TNC NREP PCDH7 OTOG	2.21e-04	167	79	4	55c3c68af269fcf40f2b080ae4489523609ad388
ToppCell	facs-Skin-Anagen-24m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 TNC LTBP3 NREP	2.21e-04	167	79	4	78909f685ccd1321064eb0887caf9263e0e54879
ToppCell	5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTPRJ CARMIL3 NRG2 MGAM2	2.27e-04	168	79	4	8072d0496b7b730c4601009eaa69ec5366d26d73
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PPARGC1B CENPF TROAP PLK1	2.27e-04	168	79	4	b7cd33f5da4f37b9384fc3bd3ca01fbc790accfc
ToppCell	facs-Lung-Endomucin-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARD9 PPFIA3 NREP ADAMTSL4	2.32e-04	169	79	4	2d23b4cee060f8adddc430c1c10d4e25205b4af6
ToppCell	Dividing_Macrophages-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	CENPF TROAP SAC3D1 PLK1	2.32e-04	169	79	4	eb0c993ef2eea73bc4881182520922ce9ae9368f
ToppCell	facs-Lung-Endomucin-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARD9 PPFIA3 NREP ADAMTSL4	2.32e-04	169	79	4	ecaf08e8e0b54d1c97a02bc1f65409fd43d68227
ToppCell	facs-Lung-Endomucin-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARD9 PPFIA3 NREP ADAMTSL4	2.32e-04	169	79	4	ad6af6609acf158cb79e45ee7ca9af332be3c40c
ToppCell	Influenza_Severe-Neutrophil\|World / Disease group and Cell class	CNTNAP3B MAK EGR1 CNTNAP3	2.32e-04	169	79	4	6e8e2580e19c96bcf7fa6a6d8c183df65f428396
ToppCell	Control-T/NK_proliferative\|World / Disease group and Cell class	CENPF TROAP SAC3D1 PLK1	2.32e-04	169	79	4	fca735cbb55fce4d32dc6632a39acea1d16b87ab
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CRACR2A PIDD1 MUC5B MUC2	2.37e-04	170	79	4	2c5a1469e5743870e96e6c2cc92f0c5096b79f51
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CRACR2A PIDD1 MUC5B MUC2	2.37e-04	170	79	4	9bea81031cdfe45e8cddac3a3afd9ca6c331c45a
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPARGC1B CARD9 ATXN7L1 PGAP4	2.37e-04	170	79	4	833b4f44ea1fa673dfc6b43ce45a79fe68ae3b05
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Ptprz1_(Ptprz1)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	NEU4 GUCY2F OTOG	2.41e-04	68	79	3	9ce22a6dea3c17d5352572ea0dabe6c6120b9f82
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Ptprz1_(Ptprz1)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	NEU4 GUCY2F OTOG	2.41e-04	68	79	3	89d337147899a978a7467db24e876a613bdd2288
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPF TROAP PLK1 DYRK3	2.42e-04	171	79	4	6e7ade1d14a3ec4c566476aac3eb509bd2661e39
Computational	Neighborhood of ARAF1	KAT7 ATXN7L1 ALDH4A1 HSF4 GSK3A	5.06e-05	78	56	5	MORF_ARAF1
Drug	Denatonium benzoate [3734-33-6]; Down 200; 9uM; MCF7; HT_HG-U133A	EGR1 SIPA1L1 GATA4 MED14 IREB2 PPFIA3 SRRM2	5.30e-06	198	78	7	6502_DN
Drug	AG-013608 [351320-38-2]; Up 200; 10uM; MCF7; HT_HG-U133A	NLGN4X IRF2BP1 CARD9 GATA4 NRG2 ALDH4A1 MUC2	5.30e-06	198	78	7	5944_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	MAK EGR1 ALDH4A1 SRRM2 CYB5R1 DYRK3	3.60e-05	180	78	6	2639_UP
Drug	testosterone-3-carboxymethyloxime-bovine serum albumin conjugate	KAT7 HSPG2 MAK EGR1 ALPK3 PAWR	4.20e-05	185	78	6	ctd:C045037
Drug	thioridazine hydrochloride; Down 200; 10uM; PC3; HT_HG-U133A	CENPF TROAP TNC TSC2 NREP PLK1	5.31e-05	193	78	6	1230_DN
Drug	Carcinine [56897-53-1]; Down 200; 22uM; PC3; HT_HG-U133A	HSPG2 IRF2BP1 NRG2 PIDD1 SEMA4G GSK3A	5.31e-05	193	78	6	4225_DN
Drug	Dipyrone [5907-38-0]; Up 200; 12uM; PC3; HT_HG-U133A	HSPG2 IRF2BP1 EGR1 ATP8A2 MUC5B GSK3A	5.47e-05	194	78	6	4310_UP
Drug	Acebutolol hydrochloride [34381-68-5]; Up 200; 10.8uM; PC3; HG-U133A	HSPG2 RHOBTB3 TSC2 LTBP3 PPFIA3 DYRK3	5.62e-05	195	78	6	1911_UP
Drug	sodium 4-phenylbutyrate; Down 200; 1000uM; PC3; HG-U133A	HSPG2 LEMD3 SIPA1L1 NUMA1 NRG2 MUC5B	5.62e-05	195	78	6	434_DN
Drug	Eburnamonine (-) [4880-88-0]; Up 200; 13.6uM; MCF7; HT_HG-U133A	IRF2BP1 EGR1 CENPF TROAP NUMA1 MED14	5.79e-05	196	78	6	2781_UP
Drug	Spiramycin [8025-81-8]; Down 200; 4.8uM; PC3; HT_HG-U133A	HSPG2 IRF2BP1 CENPF ATXN7L1 PIDD1 GSK3A	5.79e-05	196	78	6	3762_DN
Drug	Parbendazole [14255-87-9]; Down 200; 16.2uM; MCF7; HT_HG-U133A	HSPG2 EGR1 SIPA1L1 NUMA1 PIDD1 PPFIA3	5.79e-05	196	78	6	3881_DN
Drug	Oxymetazoline hydrochloride [2315-02-8]; Up 200; 13.4uM; PC3; HT_HG-U133A	MAK NRXN3 ALDH4A1 PPFIA3 ADAMTSL4 GSK3A	5.95e-05	197	78	6	6350_UP
Drug	0316684-0000 [391209-55-5]; Up 200; 10uM; MCF7; HT_HG-U133A	HSPG2 GATA4 MED14 PIDD1 PCDH7 DYRK3	5.95e-05	197	78	6	7093_UP
Drug	Fenbufen [36330-85-5]; Up 200; 15.8uM; MCF7; HT_HG-U133A	IRF2BP1 CARD9 MUC5B ALDH4A1 ADAMTSL4 GSK3A	5.95e-05	197	78	6	2308_UP
Drug	Glimepiride [93479-97-1]; Up 200; 8.2uM; HL60; HT_HG-U133A	ABLIM1 NLGN4X IRF2BP1 EGR1 ADAMTSL4 SEMA4G	6.12e-05	198	78	6	2154_UP
Drug	Zaprinast [37762-06-4]; Up 200; 14.8uM; MCF7; HT_HG-U133A	IRF2BP1 SIPA1L1 IREB2 PPFIA3 SEMA4G GSK3A	6.29e-05	199	78	6	3226_UP
Drug	Troleandomycin [2751-09-9]; Up 200; 5uM; PC3; HT_HG-U133A	NRXN3 EGR1 ATXN7L1 ATP8A2 RHOBTB3 GSK3A	6.29e-05	199	78	6	3985_UP
Drug	Methylhydantoin-5-(L) [40856-73-3]; Up 200; 35uM; MCF7; HT_HG-U133A	IRF2BP1 TNC SRRM2 PCDH7 SEMA4G GSK3A	6.47e-05	200	78	6	5679_UP
Drug	FK-506; Down 200; 1uM; MCF7; HG-U133A	IRF2BP1 EGR1 LEMD3 PPFIA3 PCDH7 ADAMTSL4	6.47e-05	200	78	6	378_DN
Disease	autism spectrum disorder (implicated_via_orthology)	CNTNAP3B NLGN3 NRXN3 NLGN4X NLGN4Y CNTNAP3 TSC2	1.36e-07	152	76	7	DOID:0060041 (implicated_via_orthology)
Disease	Left ventricular mass to end-diastolic volume ratio	SIPA1L1 ALPK3 MYO18B	3.63e-05	25	76	3	EFO_0010556
Disease	otosclerosis	MAK SIPA1L1 ALPK3 LTBP3	5.82e-05	81	76	4	EFO_0004213
Disease	Squamous cell carcinoma of lung	GUCY2F MYO18B PLK1	7.72e-05	32	76	3	C0149782
Disease	autosomal recessive intellectual developmental disorder (implicated_via_orthology)	CNTNAP3B CNTNAP3	1.81e-04	8	76	2	DOID:0060308 (implicated_via_orthology)
Disease	Hereditary spherocytosis	CAD ANK1	1.81e-04	8	76	2	C0037889
Disease	venous thromboembolism	DCHS2 PPARGC1B PTPRJ LEMD3 ATXN7L1 DLEC1 SRRM2	1.85e-04	460	76	7	EFO_0004286
Disease	Mitral valve prolapse, response to surgery	ALPK3 LTBP3	4.25e-04	12	76	2	EFO_0009951, HP_0001634
Disease	rosacea severity measurement	COL11A2 NRXN3 HERC2 MGAM2	5.74e-04	147	76	4	EFO_0009180
Disease	cholangiocarcinoma (is_marker_for)	PAWR MUC5B MUC2	6.11e-04	64	76	3	DOID:4947 (is_marker_for)
Disease	Down syndrome (implicated_via_orthology)	DOP1A DYRK3	6.73e-04	15	76	2	DOID:14250 (implicated_via_orthology)
Disease	myelodysplastic syndrome (implicated_via_orthology)	SAMD9L EGR1	6.73e-04	15	76	2	DOID:0050908 (implicated_via_orthology)
Disease	osteochondrodysplasia (is_implicated_in)	HSPG2 COL11A2	1.09e-03	19	76	2	DOID:2256 (is_implicated_in)
Disease	Brugada syndrome	GATA4 MYO18B	1.09e-03	19	76	2	MONDO_0015263
Disease	pulmonary hypertension (biomarker_via_orthology)	EGR1 TNC GATA4	1.17e-03	80	76	3	DOID:6432 (biomarker_via_orthology)
Disease	Osteoarthritis of hip	TNC LTBP3	1.21e-03	20	76	2	C0029410
Disease	Nonsyndromic Deafness	COL11A2 TNC OTOG	1.21e-03	81	76	3	C3711374
Disease	Autism Spectrum Disorders	NLGN3 NRXN3 NLGN4X	1.39e-03	85	76	3	C1510586
Disease	response to radiation	WDR64 CENPF FSHR	1.54e-03	88	76	3	GO_0009314
Disease	left ventricular structural measurement	SIPA1L1 ALPK3 MYO18B	1.54e-03	88	76	3	EFO_0008205
Disease	Malignant neoplasm of breast	PPARGC1B ANK1 CENPF GUCY2F SIPA1L1 MED14 DLEC1 HERC2 DOP1A	1.74e-03	1074	76	9	C0006142
Disease	osteoarthritis, hip	TNC LTBP3 HERC2	1.75e-03	92	76	3	EFO_1000786
Disease	caudate volume change measurement, age at assessment	NRXN3 DLEC1	2.20e-03	27	76	2	EFO_0008007, EFO_0021491
Disease	glutamate measurement	RHOBTB3 OTOG	2.54e-03	29	76	2	EFO_0010487

Protein segments in the cluster

Peptide	Gene	Start	Entry
PVTFLSSRSYLALPG	CNTNAP3	371	Q9BZ76
SSLGDRIITPYTPPR	C1orf140	6	Q5VVS0
TSPETLPLYRTQSRG	ADAMTSL4	106	Q6UY14
LRPTRTSSESIYSRP	ABLIM1	346	O14639
LESVPPGTYLSRSRS	BRD3OS	36	A0A1B0GUI7
PICTPSRSQLLTGRY	ARSI	91	Q5FYB1
RRTPTPLALRYSILS	ANK1	1376	P16157
PASRSYLLSVRPETS	ALPK3	236	Q96L96
ISVPPSTNSTVYRGL	ALDH4A1	186	P30038
TSPAVRLPGITYVLA	DOP1A	191	Q5JWR5
PRRSSLGLSGYPLTE	CRACR2A	436	Q9BSW2
LTSVIDPSRITPYLR	CARD9	21	Q9H257
VYLPSAPISSRLTSS	ATXN7L1	541	Q9ULK2
DVSPTGRYTTLVPLI	ATP8A2	111	Q9NTI2
PTLSEGLTSPRYTST	MUC5B	1651	Q9HC84
SSYLLQEPPRTVSGR	PAWR	211	Q96IZ0
TVTVPPSEGSSYRLR	HSPG2	3006	P98160
PSEGSSYRLRSPVIS	HSPG2	3011	P98160
SYRLRSPVISIDPPS	HSPG2	3016	P98160
LRVKPYIRTSLSPGS	IREB2	536	P48200
LRRYGLSPGPVTEST	LEMD3	21	Q9Y2U8
PLGSSELRSPRISYL	NREP	51	Q16612
LRPATSYVFSITPGI	PTPRJ	176	Q12913
SPERPLSDLGLISYR	KAT7	506	O95251
VTLQPTPALTYRTTG	MGAM2	1151	Q2M2H8
LPSQVYSLVGSSPLR	HIPK1	861	Q86Z02
GTVPIPRQITALSSY	HERC2	3031	O95714
SLLYRRGPGPLTLTR	FLYWCH1	371	Q4VC44
LGRYRSSCSLPPSLT	PPFIA3	646	O75145
SSYPRTLRTVRPGLS	CARMIL3	1026	Q8ND23
TRLPPITYTGRFSLE	EGR1	126	P18146
RPVGTLYLLPTATDR	PCDH7	156	O60245
TPSIIRTTGLRPYPS	MUC2	4316	Q02817
RTTGLRPYPSSVLIC	MUC2	4321	Q02817
RYVSALTTPARLSPV	NRG2	591	O14511
RTRPGLQAPLLTLYS	COL11A2	91	P13942
LRRLSPSLYSVVPAS	PGAP4	316	Q9BRR3
ASLPSPYAVTGRLLV	MROH1	531	Q8NDA8
PYAVTGRLLVVSSSP	MROH1	536	Q8NDA8
ERTGLTYRVPSLLPV	NEU4	16	Q8WWR8
GYPLRRSQSLPTTLL	ITPRID2	731	P28290
LTTGSYPRLPTCIRD	MED14	161	O60244
IRISQTTPPGTALYL	DCHS2	986	Q6V1P9
LTALPDYTLTLRRSP	NLGN3	786	Q9NZ94
TLRLTCPPDYTLTLR	NLGN4Y	751	Q8NFZ3
TPRVPSSVLGLSYLQ	GATA4	41	P43694
SSLLEYTPSSRLSPL	GSK3A	381	P49840
DIPTGKTSPYILRRT	CENPF	2991	P49454
SYPTFSRTLPSPIRV	GUCY2F	161	P51841
RAPEVLLRSSVYSSP	MAK	166	P20794
ATTTPARPYPELISR	LTBP3	531	Q9NS15
LPGALTIYSTPESRT	HSF4	466	Q9ULV5
TPGLQRTTSAGYRLP	C2orf50	6	Q96LR7
PRVTNGSTYILVPLS	FSHR	676	P23945
TTSRYLRVLPPSTPY	DLEC1	401	Q9Y238
RPPSVLLATVRYLAG	SAC3D1	116	A6NKF1
TLRLTCPPDYTLTLR	NLGN4X	751	Q8N0W4
RAPEIILGSRYSTPI	DYRK3	376	O43781
PVTFLSSRSYLALPG	CNTNAP3B	371	Q96NU0
RYDRATSSGRLPLPS	IRF2BP1	111	Q8IU81
PAGATATPITIRYRL	PIDD1	346	Q9HB75
LSLPGYRPTTRSSAR	NUMA1	1871	Q14980
PSGLIRTYLGRSPLV	RHOBTB3	21	O94955
PVPTSYALSRVSART	OTOG	1971	Q6ZRI0
TSPRVPLSAYERVSG	SRRM2	2381	Q9UQ35
IPVISVYSGPLRSGR	SAMD9L	1546	Q8IVG5
VRALTPLTSSYRDVP	SEC24A	221	O95486
SVPISIYRSPVSLRG	NRXN3	66	Q9HDB5
LATPVYASLTPRSRP	PPARGC1B	361	Q86YN6
SSTYPSLPKSLPLRR	SIPA1L1	1616	O43166
STRIDGSLVIRPYTP	CYB5R1	86	Q9UHQ9
GLTVTPNPARTIYTT	TXN2	41	Q99757
PNPARTIYTTRISLT	TXN2	46	Q99757
ATLNRLTVPRYSIPT	TULP4	941	Q9NRJ4
TLLASYSLTVRPATP	SEMA4G	641	Q9NTN9
LPRNTTSYVLRGLEP	TNC	1031	P24821
GPPTLTSYSVLRRLT	TROAP	336	Q12815
TPLNALGSPYRVITS	RXRG	61	P48443
PASYPSVVSTLSRVL	CAD	226	P27708
PTLPIYQTTGASTLR	MYO18B	2276	Q8IUG5
YLPELSLSRLSSTTP	PRRG3	176	Q9BZD7
LASPPSAVIGRYLLS	TGM6	101	O95932
ELRRVSVPYPSSLLS	THAP4	396	Q8WY91
LRPRGYTISDSAPSR	TSC2	1456	P49815
SLPIYSISSPTSLRF	WDR64	1011	B1ANS9
TSGYIPARLPITCLT	PLK1	306	P53350