Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessregulation of cholangiocyte proliferation

PKHD1 NPPB HDAC6

4.05e-078413GO:1904054
GeneOntologyBiologicalProcesscholangiocyte proliferation

PKHD1 NPPB HDAC6

8.66e-0710413GO:1990705
DomainARM-type_fold

TMCO6 RICTOR APOB ARID1A GCN1 NBEAL2

9.00e-05339416IPR016024
DomainARM-like

TMCO6 RICTOR ARID1A GCN1 NBEAL2

2.98e-04270415IPR011989
Domainzf-DHHC

ZDHHC11 ZDHHC1

1.16e-0323412PF01529
DomainDHHC

ZDHHC11 ZDHHC1

1.37e-0325412PS50216
DomainZnf_DHHC_palmitoyltrfase

ZDHHC11 ZDHHC1

1.37e-0325412IPR001594
Domain-

TMCO6 RICTOR ARID1A GCN1

1.39e-032224141.25.10.10
DomainLAM_G_DOMAIN

HSPG2 CRB2

3.14e-0338412PS50025
DomainLaminin_G_2

HSPG2 CRB2

3.48e-0340412PF02210
DomainARM

TMCO6 GCN1

3.48e-0340412SM00185
DomainLamG

HSPG2 CRB2

4.20e-0344412SM00282
DomainArmadillo

TMCO6 GCN1

4.77e-0347412IPR000225
DomainER_TARGET

TXNDC5 RCN3

4.77e-0347412PS00014
DomainLaminin_G

HSPG2 CRB2

7.19e-0358412IPR001791
Pubmed

Variation in Niemann-Pick C1-like 1 gene as a determinant of apolipoprotein B-100 kinetics and response to statin therapy in centrally obese men.

APOB NPC1L1

1.49e-06243218031309
Pubmed

ARID1A-deficient cells require HDAC6 for progression of endometrial carcinoma.

HDAC6 ARID1A

1.49e-06243235167193
Pubmed

Clinicopathological correlation of ARID1A status with HDAC6 and its related factors in ovarian clear cell carcinoma.

HDAC6 ARID1A

1.49e-06243230787326
Pubmed

ARID1A-mutated ovarian cancers depend on HDAC6 activity.

HDAC6 ARID1A

4.48e-06343228737768
Pubmed

HDAC6 regulates glucocorticoid receptor signaling in serotonin pathways with critical impact on stress resilience.

GCGR HDAC6

4.48e-06343222457490
Pubmed

Itch-associated peptides: RNA-Seq and bioinformatic analysis of natriuretic precursor peptide B and gastrin releasing peptide in dorsal root and trigeminal ganglia, and the spinal cord.

NPPB NMB

4.48e-06343225123163
Pubmed

Nucleotide oligomerization domain-containing proteins instruct T cell helper type 2 immunity through stromal activation.

NOD1 TNFRSF4

1.49e-05543221856952
Pubmed

BNP facilitates NMB-encoded histaminergic itch via NPRC-NMBR crosstalk.

NPPB NMB

3.12e-05743234919054
Pubmed

In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin palmitoylation in its targeting to Rab5-positive endosomes.

ZDHHC11 ZDHHC1

3.12e-05743223687301
Pubmed

Deficiency in Crumbs homolog 2 (Crb2) affects gastrulation and results in embryonic lethality in mice.

HSPG2 CRB2

9.78e-051243222072575
Pubmed

Maternal diabetes causes coordinated down-regulation of genes involved with lipid metabolism in the murine fetal heart.

NPPB APOB

1.35e-041443218502258
Pubmed

Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins.

ZDHHC11 ZDHHC1

2.80e-042043216647879
Pubmed

DOT1L regulates dystrophin expression and is critical for cardiac function.

HSPG2 NPPB

3.09e-042143221289070
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

RDH14 APOB TXNDC5 GCN1 TMEM245

3.66e-0449943522810586
Pubmed

UBR-box containing protein, UBR5, is over-expressed in human lung adenocarcinoma and is a potential therapeutic target.

RICTOR GCN1

6.35e-043043232867711
Pubmed

Mechanistic target of rapamycin (Mtor) is essential for murine embryonic heart development and growth.

RICTOR NPPB

8.17e-043443223342106
Pubmed

Transcriptional analysis of cleft palate in TGFβ3 mutant mice.

KCP HSPG2

8.66e-043543232913205
CytobandEnsembl 112 genes in cytogenetic band chr1p36

C1QC HSPG2 NPPB RNF186 ARID1A TNFRSF4

3.98e-05681436chr1p36
CytobandEnsembl 112 genes in cytogenetic band chr2p24

RDH14 APOB

2.65e-0381432chr2p24
GeneFamilyZinc fingers DHHC-type|Ankyrin repeat domain containing

ZDHHC11 ZDHHC1

5.81e-042427276
CoexpressionGSE15271_CXCR4_POS_VS_NEG_GC_BCELL_DN

IER5 NMB ARID1A RCN3 KCNRG

9.82e-06175435M7101
CoexpressionAtlasadipose tissue

TMEM132C MYEOV NMB SCN4A TNFRSF4

1.60e-05161425adipose tissue
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCP HSPG2 NMB TXNDC5 RCN3

1.13e-06192435671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCP HSPG2 NMB TXNDC5 RCN3

1.13e-06192435840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GPR78 TMEM132C C3orf80 CRB2 STEAP1

1.29e-0619743531c8d6e565bbdc37843ce871fe91845b0cc18a9f
ToppCellnormal_Pleural_Fluid-B_lymphocytes-Plasma_cells|B_lymphocytes / Location, Cell class and cell subclass

C1QC HSPG2 NMB MFHAS1

1.43e-05153434a156710217ef07c07a80ca6504fa0784d86380fa
ToppCell-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

TMEM132C TXNDC5 STEAP1 TNFRSF4

1.54e-05156434f0c4d9d58365b0ae8e10ba1aaf3847fb3f98c7ad
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RICTOR RNF186 MYEOV NBEAL2

1.93e-0516543434fd00be2b28716c871ad9fb356de84a299a0c01
ToppCelldroplet-Thymus-nan-3m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM132C C1QC GCGR VSIG10

2.32e-0517343463f03abca84ae021ff34ff34537838aa8a1ccd11
ToppCelldroplet-Limb_Muscle-nan-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QC HSPG2 NMB CSF3R

2.71e-05180434d3d0be136fff5d3e39ecf5a5dbefc1d0d0a6c814
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

VSIG10 ARID1A RASGRF2 TMEM245

3.08e-05186434de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

VSIG10 ARID1A RASGRF2 TMEM245

3.08e-051864340b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 KCP MFHAS1 NUAK2

3.41e-051914349032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PKHD1 KCP MFHAS1 NUAK2

3.41e-051914345717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM132C HSPG2 RCN3 ISM1

3.48e-0519243429bee88b45e23f16543ffc7cc361bc5da5d16a2b
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PKHD1 VSIG10 NBEAL2 TMEM245

3.48e-0519243429f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM132C HSPG2 RCN3 ISM1

3.48e-05192434cdc652dbfabe41b324fd85c1ed933d29fb73a49f
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 NMB TXNDC5 RCN3

3.55e-0519343449600db68ed65cafc67bd45a285b364e4f5f88af
ToppCellfacs-Lung-nan-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM132C HSPG2 RCN3 ISM1

3.55e-05193434d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 NMB TXNDC5 RCN3

3.55e-0519343445b5cab4dfeb0ed3b13631db5963740a792b810f
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM132C HSPG2 RCN3 ISM1

3.70e-051954340feb6ebe7b4b781dec7cfaef844140cfbf84b4b9
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM132C HSPG2 RCN3 ISM1

3.70e-051954342a6f67875cef140b0e6b8401436719675c6b3665
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM132C TXNDC5 RCN3 ISM1

3.77e-05196434d4676a6b0d9e417795fc9a6bcb1762d3dd656ca9
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HSPG2 C3orf80 RCN3 STEAP1

3.93e-051984348b9e8eaeffda40912a0163fdf39b93bc5e64751c
ToppCellfacs-Trachea-nan-3m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 TXNDC5 RCN3 ISM1

3.93e-051984340dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HSPG2 C3orf80 RCN3 STEAP1

3.93e-05198434eb78b2ae6a787dbc75947e8dd5a03693285bc8be
ToppCellfacs-Trachea-nan-3m-Mesenchymal|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 TXNDC5 RCN3 ISM1

4.00e-0519943467f78c070c56e44fba36542041bf7fa1c291807c
ToppCellfacs-Trachea-nan-3m-Mesenchymal-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 TXNDC5 RCN3 ISM1

4.00e-051994341ae244b563f85c1ee8d22698f478c842a4d9c7f5
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PKHD1 C1QC HDAC6

1.46e-04106433005ca899efc5ad0c9c17b2697022b594c8cea2c1
ToppCellTCGA-Bile_Duct|World / Sample_Type by Project: Shred V9

PKHD1 APOB NPC1L1

3.32e-04140433ca8a0ccbc2f501b759864fe9bb06dc8b44b6b31f
ToppCell10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasmablast|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GDAP1L1 TXNDC5 ZDHHC11

3.39e-0414143316b96e9f90231e84b5150b5c239599b3dc28b768
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-AT1_-_meso|E18.5-samps / Age Group, Lineage, Cell class and subclass

RASGRF2 NBEAL2 TNFRSF4

3.46e-0414243377fd145c1c500d580f70ac4e54c3fd879ecf0ab3
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

C1QC MFHAS1 KCNRG

3.46e-041424335ef69032ed7dc5f2244b84e8c6662290bf59a34b
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma|TCGA-Pancreas / Sample_Type by Project: Shred V9

MYEOV STEAP1

4.35e-0432432b2d87153b4aefefd7b5e31ea67aa43e5f599e734
ToppCellTCGA-Pancreas-Primary_Tumor|TCGA-Pancreas / Sample_Type by Project: Shred V9

MYEOV STEAP1

4.35e-0432432f5bcaacbddfb85439ebf5908762bf39cb72b727c
ToppCelldroplet-Fat-Mat-18m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 APOB RNF186

4.56e-04156433cfd7f56f3155db677684827607e9008e975dbe70
ToppCelldroplet-Fat-Mat-18m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 APOB RNF186

4.56e-041564330d79b4172896574b00faf00e87254f68d76f5512
ToppCelldroplet-Fat-Mat-18m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1 APOB RNF186

4.56e-04156433f09150aacb6121f913648ed3918f9cd4f22c61f2
ToppCell368C-Myeloid-Dendritic-cDC_activated|368C / Donor, Lineage, Cell class and subclass (all cells)

GCGR TNFRSF4 NUAK2

4.91e-04160433bcd90ef96464bd901b87b94c696de70c113bfd03
ToppCellfacs-Marrow-T-cells-24m-Hematologic-MPP_Fraction_B|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RICTOR RCN3 SCN4A

4.91e-04160433b3f7ef7e682b48a83ca425f5c439336e96168300
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW13-Neuronal-Cortical_neuron|GW13 / Sample Type, Dataset, Time_group, and Cell type.

RICTOR MFSD3

4.91e-04344326c9c477b43009cded5a2e1a1792c32c40d9309a8
ToppCellControl-Lymphocyte-B-Plasmablast|Control / Disease, Lineage and Cell Type

C3orf80 MYEOV TXNDC5

5.09e-0416243367b32c40cc180c5ebbfd901a417b5be469500110
ToppCell368C-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

GCGR TNFRSF4 NUAK2

5.27e-0416443367c636a2cc32e56c6186dc7e779cc19af04639d2
ToppCellT_cells-TFH-like_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

NMB VSIG10 TNFRSF4

5.27e-04164433b10cf59f4cc37ca6cd0ecf71d7de278cc2bdd8b5
ToppCell368C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

GCGR TNFRSF4 NUAK2

5.37e-041654339d2bdc42c13c8c2a68889bec8612a1ce56f659fa
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PKHD1 C1QC SCN4A

5.46e-04166433bb8135119dc37fdbba476599a56d368f422688dc
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

RASGRF2 ISM1 TNFRSF4

5.56e-0416743394642b3dae035fedb6e8b9745f440096a4539f3c
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RNF186 MYEOV STEAP1

5.56e-041674337cb5b52aaa5b595fe2e97d9e175294ea8d63b165
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell-NK|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

RASGRF2 ISM1 TNFRSF4

5.56e-0416743342b299273a6c72a625b204d55f4f3c4eebd6d185
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell-NK-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RASGRF2 ISM1 TNFRSF4

5.56e-04167433ecf5bc634e1e01efd783617eb81d1704e903ea21
ToppCelldroplet-Thymus-nan-21m-Myeloid-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IER5 TXNDC5 SCN4A

5.66e-0416843369dd747be46e7fbcec571cddd6dee374b9c2507a
ToppCellfacs-Marrow-T-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QC NPPB TNFRSF4

5.66e-041684330ece1e196d17c0f276424abd5cb43d528f40224b
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PKHD1 CRB2 ISM1

5.66e-04168433a086c306be430adf0632ba53e98cd8014d2de330
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HDAC6 CSF3R GCN1

5.66e-04168433c3d2d573f21350a4a674faff30b06ff644d00ac3
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RICTOR SCN4A TNFRSF4

5.95e-041714336f49537f8d3cf18e65aa999fec32ed347ce2da3e
ToppCellcontrol-Myeloid-Monocyte-derived_Macrophage|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CSF3R RCN3 TNFRSF4

5.95e-04171433e828b684744a4fdf6b63ec033c4f000b39ca0d51
ToppCellfacs-Marrow-B-cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RICTOR SCN4A TNFRSF4

5.95e-04171433ab97ae2b127a585f170f028f1c475cdd1b0cdea5
ToppCell356C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TMCO6 NOD1 VSIG10

5.95e-041714333d26ef58fe5231373d7df9ac79d225546918cf82
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C3orf80 NMB TNFRSF4

5.95e-041714338719a18c9e6b6f5d8ec4e937c2bda1e36441c9ec
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C3orf80 NMB TNFRSF4

5.95e-04171433f4cdd7862c8fe99ee765a2f3ed375b584f4976c5
ToppCell356C-Lymphocytic-ILC-ILC-2|ILC / Donor, Lineage, Cell class and subclass (all cells)

TMCO6 NOD1 VSIG10

6.06e-041724334977e1f4deae781750e27a8054deccd336cfb74a
ToppCelldroplet-Spleen-nan-21m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TXNDC5 RCN3 TNFRSF4

6.06e-041724333dc02709c2a6be2155576e5c34e1b0b3ae19b061
ToppCellNS-critical-d_0-4-Epithelial-FOXN4+|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

HSPG2 HDAC6 TXNDC5

6.06e-04172433a00bb44d33658cb3a98accd6b60f3ce964c425b4
ToppCellControl-Endothelial_cells-Systemic_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

HSPG2 RASGRF2 TNFRSF4

6.06e-04172433c55dce1ed3ed7312394b4e050e1de852a994e130
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-Th1|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PKHD1 CRB2 TNFRSF4

6.06e-04172433c0c9a3f5b5fb942b049bc159fd9f21b5b706edd2
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C1QC CSF3R GCN1

6.16e-0417343312c6875f881cb0fbff09d753b53c1cce7a95527f
ToppCellNS-control-d_0-4-Myeloid-Monocyte-derived_Macrophage|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CSF3R RCN3 TNFRSF4

6.26e-04174433758984730cd1c3ccf6866a3a8f03d6e002f3edb6
ToppCelldroplet-Lung-nan-18m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C3orf80 VSIG10 TNFRSF4

6.47e-0417643324b2e94ee5defcefb64a1f2447a2cc71b015b0fd
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|390C / Donor, Lineage, Cell class and subclass (all cells)

TMEM132C TXNDC5 RCN3

6.47e-04176433852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|390C / Donor, Lineage, Cell class and subclass (all cells)

TMEM132C TXNDC5 RCN3

6.47e-04176433d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

C3orf80 VSIG10 TNFRSF4

6.58e-04177433f360f7099570d248531897b96e0de282e58f59e9
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PKHD1 HSPG2 NBEAL2

6.58e-041774339af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellPND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CSF3R NBEAL2 GP1BB

6.69e-0417843363f5880a5b514e20ef2c07a6a9cb8df34e6cede5
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6|TCGA-Ovary / Sample_Type by Project: Shred V9

C3orf80 RASGRF2 ISM1

6.69e-04178433142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCellPND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CSF3R NBEAL2 GP1BB

6.69e-0417843382c84f8b8a7e6a3d3be3351b348a37143279c100
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QC APOB MFHAS1

6.69e-041784336d9ecfaeb50d562899380de379ebf7b99fd8adc9
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QC APOB MFHAS1

6.69e-04178433d3f518cd75b02e85d45cbb9b2eff30f0272512a8
ToppCellT_cells-TFH-like_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

NMB VSIG10 TNFRSF4

6.69e-04178433e2ae43e5ec31de6197f2cbd6089f944adbf0a163
ToppCellControl-T/NK-NK|Control / Disease group,lineage and cell class （2021.01.30）

RASGRF2 ISM1 TNFRSF4

6.69e-04178433079fd19bdeed86bf985c4083af432432d66ad546
ToppCellPND14-Immune-Immune_Myeloid-Megakaryocyte/Platelet|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CSF3R NBEAL2 GP1BB

6.69e-04178433cb91558469ae0748106fb0b6d702edb0ff21a884
ToppCellfacs-Lung-EPCAM-24m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCP TNFRSF4 NUAK2

6.80e-0417943351872338e54c5f3e42ca9f1c4cf1e8b0cb84afcc
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCP TNFRSF4 NUAK2

6.80e-041794331b979e0203a2ddfe98bf6c2c80c4af1ba437a80f
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RICTOR RASGRF2 MFHAS1

6.80e-041794336bbb32d7e582a96cb3cfc3eb911b05d518e7d5e9
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 RASGRF2 TNFRSF4

6.91e-04180433755050226eeb1991ee7f0d15e39d0458f3e4a791
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

C1QC ZDHHC11 RCN3

6.91e-04180433fb8bc639f7f94e7aed9f9d708d5d5c78178533ae
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-LYVE1+_Macrophage|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C1QC CSF3R KCNRG

6.91e-0418043366c7b02d85e32ba3e7530d0c4aff17e7525ccdd8
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

HSPG2 RASGRF2 TNFRSF4

6.91e-041804335861b44acfb8fe92c281c8355bf19c059b3dcd64
ToppCelldroplet-Thymus-nan-24m-Myeloid-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IER5 TXNDC5 NUAK2

7.02e-041814332a3092fbadd18967199f1203c11f0dd956417254
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PKHD1 HSPG2 RASGRF2

7.13e-04182433573771130247e869e4e58f22d4a1cb31989635cf
ToppCellwk_08-11-Mesenchymal-Chondrocyte-ASPN+_chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RCN3 STEAP1 ISM1

7.13e-041824330e52ba34e179d9bfaac7b49920b44c710b2b8dad
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PKHD1 HSPG2 RASGRF2

7.13e-041824336cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCellfacs-Thymus-Flowthrough-24m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IER5 TXNDC5 NUAK2

7.25e-041834330513bb73552bfee609877d924fa97684200f595c
ToppCellfacs-Thymus-Flowthrough-24m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IER5 TXNDC5 NUAK2

7.25e-041834336eeef55071ae25a61616df4fcfb2cea560aa7923
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-1|TCGA-Thryoid / Sample_Type by Project: Shred V9

C3orf80 RCN3 STEAP1

7.25e-0418343306e4b05d86a7d643569e19575c2c9aa351d33f29
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

C1QC IER5 CSF3R

7.25e-0418343362f76907e501bba6e1010b5c447faed5f0ef93a7
ToppCellfacs-Thymus-Flowthrough-24m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IER5 TXNDC5 NUAK2

7.25e-0418343385b2335fa938a94e74251bd8d99de1bd21265ac9
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM132C C3orf80 GDAP1L1

7.36e-041844334a9f798c67b9998bffe44242b210cc1e224ff5b1
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

APOB CSF3R NBEAL2

7.36e-041844337ecdf2645e9378cf2f5ce4557f2cf100e6f184ba
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_MEMP|bone_marrow / Manually curated celltypes from each tissue

C3orf80 GCGR GP1BB

7.36e-04184433b81a2a95944cee8fec13d63dc0d95496e67aa937
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PKHD1 KCP RASGRF2

7.36e-041844337f6c8912677764d438ab0555faca344d74c2f483
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RCN3 STEAP1 ISM1

7.36e-04184433e33e2a887aafba7b6a31f00bb0dbe974b4359fd6
ToppCellmild-Myeloid-Neutrophils_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

RICTOR CSF3R NUAK2

7.36e-041844331a0e8b20b3ac8416d05c2d5934ab4ac80be4cce5
Diseaselow density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

APOB MFHAS1 RCN3 NPC1L1

6.67e-05153424EFO_0004611, EFO_0020944
Diseaseresponse to ketamine, dissociation measurement

GDAP1L1 RASGRF2

1.53e-0413422EFO_0009748, EFO_0009750
Diseasegallbladder cancer (is_implicated_in)

RICTOR APOB

1.53e-0413422DOID:3121 (is_implicated_in)
Diseasepolycystic kidney disease (implicated_via_orthology)

NPPB HDAC6

1.78e-0414422DOID:0080322 (implicated_via_orthology)
Diseaseapolipoprotein A 1 measurement, apolipoprotein B measurement

APOB ARID1A NPC1L1

4.80e-04107423EFO_0004614, EFO_0004615
Diseasebrain stem volume measurement

MYEOV TXNDC5

5.35e-0424422EFO_0010605
Diseaseantihyperlipidemic drug use measurement

APOB ARID1A NPC1L1

5.93e-04115423EFO_0803367
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

APOB ARID1A MFHAS1 NPC1L1

7.72e-04291424EFO_0008317, EFO_0020946
Diseasecolon cancer (is_implicated_in)

RICTOR ARID1A

1.21e-0336422DOID:219 (is_implicated_in)
DiseaseCardiovascular Diseases

NPPB APOB

1.21e-0336422C0007222

Protein segments in the cluster

PeptideGeneStartEntry
SVLLLLLLLRHGAQG

RCN3

6

Q96D15
AGALLLALLLHGRLL

HSPG2

6

P98160
VLLGATLHRLKFLGL

GDAP1L1

271

Q96MZ0
GLLLILGKLILLHHK

ARID1A

2006

O14497
LLLGVHLATLGGNLL

OR10AC1

31

Q8NH08
SLLLHKLLLGTSGEG

MFHAS1

746

Q9Y4C4
LLLLGLLSGILAARK

CRB2

1236

Q5IJ48
LAAQLALLGLGLLHA

GP1BB

151

P13224
ALLGLGLLHALLLVL

GP1BB

156

P13224
LLLALAILGGLSKLH

GCGR

156

P47871
LVLLANLLSGKLLKG

NOD1

311

Q9Y239
VSGASPLLLHHLLLL

MYEOV

291

Q96EZ4
LLSSLGGFKLAHGLL

GCN1

591

Q92616
LGLLIDTLLKEGFHL

KCNRG

211

Q8N5I3
LLLLLFLHLAFLGGR

NPPB

11

P16860
SGVLLVNLSLGHLLL

GPR78

41

Q96P69
LLATLELLGKLLLGT

MFSD3

361

Q96ES6
HLGDKGLLLLLRFLS

RICTOR

796

Q6R327
LLITLLGLLHGLVFL

NPC1L1

1271

Q9UHC9
SSLPHLGLKLLLLLL

C1QC

6

P02747
FASLHDLQLLGKLLL

APOB

786

P04114
KLSGLLILLVLFAIG

C3orf80

81

F5H4A9
LHIILGLFGLLLLLT

CSF3R

626

Q99062
LTHLLMGLAGGKLIL

HDAC6

366

Q9UBN7
AELLLLLGLLLLTLH

ISM1

6

B1AKI9
AAHLLLLALLIILIG

RNF186

156

Q9NXI6
GGIKLHKNLLVSLVL

IER5

26

Q5VY09
AKAFLLGLLHGKILS

SCN4A

836

P35499
GALSLLLGALLGKVI

TMEM132C

16

Q8N3T6
GKLHLLKTGGVLSLI

RASGRF2

511

O14827
AAALSLLLHLGALAL

KCP

6

Q6ZWJ8
GALDLLLALLHGSLV

NBEAL2

1131

Q6ZNJ1
SILNLLHIKGGKLIF

PKHD1

1961

P08F94
LGHFLLTNLLLGLLK

RDH14

166

Q9HBH5
ASGLLLHRKGILKLN

NUAK2

491

Q9H093
KLGIVSLLLGTIHAL

STEAP1

256

Q9UHE8
HDLLGILLLKKALGV

NMB

86

P08949
LIGHGALSTLGLLLL

TMCO6

276

Q96DC7
LLLLGLGLSTVTGLH

TNFRSF4

16

P43489
LLLDFLGLVHLGQLL

ZDHHC11

241

Q9H8X9
GLGCKAILLLIFHLL

TMEM245

771

Q9H330
LLLLGLAIISGLLLH

VSIG10

421

Q8N0Z9
AALTALLLLLLGHGG

TXNDC5

16

Q8NBS9
ILLGLLSTALLGHLL

ZDHHC1

251

Q8WTX9