Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

1.98e-08111725GO:0004523
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 MRPL44 ERVK-7 ERVK-10 DROSHA ERVK-8 ERVK-11

2.58e-08371727GO:0016891
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

8.41e-08141725GO:0003964
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 MRPL44 ERVK-7 ERVK-10 DROSHA ERVK-8 ERVK-11

1.26e-07461727GO:0016893
GeneOntologyMolecularFunctiontransition metal ion binding

TRHDE ERVK-6 MBTD1 TUT4 AOC1 CYP4Z1 FNTB EARS2 MMP28 CYP11A1 ACR SLU7 RIOX1 ERVK-7 ERVK-10 HEPH CYP4Z2P LOXL2 ERVK-8 OGFOD1 KDM2A SMPD1 TRIM16L MMP10 AGBL2 ERVK-11 ZMAT1 ALOX12B RABGGTA

3.47e-07118917229GO:0046914
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

8.14e-07211725GO:0035613
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-6 MRPL44 ERVK-7 ERVK-10 DROSHA ERVK-8 ERVK-11

5.36e-06791727GO:0004521
GeneOntologyMolecularFunctionkainate selective glutamate receptor activity

GRIK1 GRIK2 GRIK5

1.23e-0561723GO:0015277
GeneOntologyMolecularFunctionpeptidase activity

TRHDE ERVK-6 MMP28 ACR ERVK-7 ERMP1 ERVK-10 PRSS36 ZUP1 PM20D2 ADAMTS10 JMJD7 RHBDL3 MIPEP CMA1 ERVK-8 MMP10 AGBL2

1.47e-0565417218GO:0008233
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

1.78e-05381725GO:0034061
GeneOntologyMolecularFunctionnucleotidyltransferase activity

ERVK-6 TUT4 ERVK-7 ERVK-10 PAPOLG RPAP1 ERVK-8 ERVK-11

5.27e-051521728GO:0016779
GeneOntologyMolecularFunctionzinc ion binding

TRHDE ERVK-6 MBTD1 TUT4 FNTB EARS2 MMP28 ACR SLU7 ERVK-7 ERVK-10 ERVK-8 KDM2A SMPD1 TRIM16L MMP10 AGBL2 ERVK-11 ZMAT1 RABGGTA

8.70e-0589117220GO:0008270
GeneOntologyMolecularFunctionendopeptidase activity

ERVK-6 MMP28 ACR ERVK-7 ERVK-10 PRSS36 ADAMTS10 JMJD7 RHBDL3 MIPEP CMA1 ERVK-8 MMP10

9.40e-0543017213GO:0004175
GeneOntologyMolecularFunctionRNA nuclease activity

ERVK-6 MRPL44 ERVK-7 ERVK-10 DROSHA ERVK-8 ERVK-11

1.79e-041361727GO:0004540
GeneOntologyMolecularFunctionendonuclease activity

ERVK-6 MRPL44 ERVK-7 ERVK-10 DROSHA ERVK-8 ERVK-11

1.79e-041361727GO:0004519
GeneOntologyMolecularFunctionchondroitin sulfate proteoglycan binding

SEMA5A PTPRF

2.20e-0431722GO:0035373
GeneOntologyMolecularFunctionribonuclease III activity

MRPL44 DROSHA

2.20e-0431722GO:0004525
GeneOntologyMolecularFunctiondouble-stranded RNA-specific ribonuclease activity

MRPL44 DROSHA

2.20e-0431722GO:0032296
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8

2.81e-04371724GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8

3.12e-04381724GO:0070001
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIK1 GRIK2 GRIK5

3.91e-04171723GO:0004970
GeneOntologyMolecularFunctionhistone H3K36me/H3K36me2 demethylase activity

RIOX1 KDM2A

4.38e-0441722GO:0140680
GeneOntologyMolecularFunctionligand-gated sodium channel activity

GRIK1 GRIK2 GRIK5

4.66e-04181723GO:0015280
GeneOntologyMolecularFunctioniron ion binding

CYP4Z1 CYP11A1 RIOX1 HEPH CYP4Z2P OGFOD1 ALOX12B

5.99e-041661727GO:0005506
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

ERVK-6 MRPL44 SGPP2 ERVK-7 ERVK-10 NT5DC3 PPP3CA PPP3CC PTPRF G6PC3 DROSHA DDHD1 ERVK-8 SMPD1 PLD2 ERVK-11 PLD4

6.21e-0480717217GO:0016788
GeneOntologyMolecularFunctioncalmodulin-dependent protein phosphatase activity

PPP3CA PPP3CC

7.25e-0451722GO:0033192
GeneOntologyMolecularFunctioncalcium channel activity

TRPM7 PANX1 GRIK1 PKD1L2 CACNA2D4 SLC24A2

8.89e-041291726GO:0005262
GeneOntologyMolecularFunctionnuclease activity

ERVK-6 MRPL44 ERVK-7 ERVK-10 DROSHA ERVK-8 ERVK-11 PLD4

9.02e-042311728GO:0004518
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

ERVK-6 TUT4 EARS2 MRPL44 SLU7 ERVK-7 ERVK-10 DUS1L DROSHA ERVK-8 ERVK-11

1.01e-0341717211GO:0140098
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GRIK1 GRIK2 GRIK5

1.11e-03241723GO:0099507
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

CYP4Z1 CYP11A1 RIOX1 CYP4Z2P JMJD7 OGFOD1 KDM2A

1.49e-031941727GO:0016705
GeneOntologyMolecularFunctionextracellularly glutamate-gated ion channel activity

GRIK1 GRIK2

1.51e-0371722GO:0005234
GeneOntologyMolecularFunctionglutamate receptor activity

GRIK1 GRIK2 GRIK5

1.58e-03271723GO:0008066
GeneOntologyMolecularFunctiondioxygenase activity

RIOX1 JMJD7 OGFOD1 KDM2A ALOX12B

1.59e-03981725GO:0051213
GeneOntologyMolecularFunctionmetallopeptidase activity

TRHDE MMP28 ERMP1 ADAMTS10 MIPEP MMP10 AGBL2

1.77e-032001727GO:0008237
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

TRPM7 PANX1 GRIK1 PKD1L2 CACNA2D4 SLC24A2

1.99e-031511726GO:0015085
GeneOntologyMolecularFunctionprotein prenyltransferase activity

FNTB RABGGTA

2.00e-0381722GO:0008318
GeneOntologyMolecularFunctionphospholipase D activity

PLD2 PLD4

2.00e-0381722GO:0004630
GeneOntologyMolecularFunctioncalcium-dependent protein serine/threonine phosphatase activity

PPP3CA PPP3CC

2.00e-0381722GO:0004723
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

RIOX1 JMJD7 OGFOD1 KDM2A

2.39e-03651724GO:0016706
GeneOntologyMolecularFunctionsyndecan binding

SEMA5A CHRD

2.55e-0391722GO:0045545
GeneOntologyMolecularFunctionexopeptidase activity

TRHDE ERMP1 PM20D2 JMJD7 AGBL2

2.64e-031101725GO:0008238
GeneOntologyMolecularFunctionhistone H3K36 demethylase activity

RIOX1 KDM2A

3.86e-03111722GO:0051864
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DENND2A EPS8L2 RALGPS2 ALS2CL DENND2B DENND4B DENND2C

3.95e-032311727GO:0005085
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

ERVK-6 TUT4 EARS2 MRPL44 SLU7 ERVK-7 ERVK-10 DUS1L DQX1 DROSHA ERVK-8 ERVK-11 PLD4

3.96e-0364517213GO:0140640
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

3.44e-08131625GO:0015074
GeneOntologyBiologicalProcessRNA-templated DNA biosynthetic process

ERVK-6 ATR CTC1 ERVK-7 ERVK-10 ERVK-8 ERVK-11

4.07e-06831627GO:0006278
GeneOntologyBiologicalProcessDNA synthesis involved in DNA repair

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-11

3.66e-05481625GO:0000731
GeneOntologyCellularComponentkainate selective glutamate receptor complex

GRIK1 GRIK2 GRIK5

1.02e-0561693GO:0032983
GeneOntologyCellularComponentribonuclease III complex

MRPL44 DROSHA

1.94e-0431692GO:1903095
GeneOntologyCellularComponentmicroprocessor complex

MRPL44 DROSHA

1.94e-0431692GO:0070877
DomainuDENN

DENND2A DENND2B DENND4B DENND2C

5.49e-06141654SM00800
DomainuDENN

DENND2A DENND2B DENND4B DENND2C

7.43e-06151654PF03456
DomainDENN

DENND2A DENND2B DENND4B DENND2C

9.84e-06161654SM00799
DomainDENN

DENND2A DENND2B DENND4B DENND2C

9.84e-06161654PF02141
DomaindDENN

DENND2A DENND2B DENND4B DENND2C

9.84e-06161654PF03455
DomainUDENN

DENND2A DENND2B DENND4B DENND2C

9.84e-06161654PS50946
DomainDDENN

DENND2A DENND2B DENND4B DENND2C

9.84e-06161654PS50947
DomaindDENN

DENND2A DENND2B DENND4B DENND2C

9.84e-06161654SM00801
DomaindDENN_dom

DENND2A DENND2B DENND4B DENND2C

9.84e-06161654IPR005112
DomainuDENN_dom

DENND2A DENND2B DENND4B DENND2C

9.84e-06161654IPR005113
DomainDENN

DENND2A DENND2B DENND4B DENND2C

9.84e-06161654PS50211
DomainDENN_dom

DENND2A DENND2B DENND4B DENND2C

9.84e-06161654IPR001194
DomainSIX1_SD

SIX1 SIX6 SIX2

2.31e-0571653IPR031701
DomainSIX1_SD

SIX1 SIX6 SIX2

2.31e-0571653PF16878
DomainJMJC

RIOX1 JMJD7 JMJD8 KDM2A

1.74e-04321654PS51184
DomainJmjC_dom

RIOX1 JMJD7 JMJD8 KDM2A

1.74e-04321654IPR003347
DomainJmjC

RIOX1 JMJD7 JMJD8 KDM2A

1.97e-04331654SM00558
DomainMAGE

MAGEB4 MAGEF1 MAGEB10 MAGEC1

2.22e-04341654SM01373
DomainRibonuclease_3

MRPL44 DROSHA

2.31e-0431652PF00636
DomainRIBOc

MRPL44 DROSHA

2.31e-0431652SM00535
DomainRNase_III_dom

MRPL44 DROSHA

2.31e-0431652IPR000999
DomainRNASE_3_1

MRPL44 DROSHA

2.31e-0431652PS00517
DomainRNASE_3_2

MRPL44 DROSHA

2.31e-0431652PS50142
Domain-

MRPL44 DROSHA

2.31e-04316521.10.1520.10
Domain-

RASA4 RASA4B

2.31e-04316524.10.1130.10
DomainMAGE

MAGEB4 MAGEF1 MAGEB10 MAGEC1

2.78e-04361654PS50838
DomainMHD_dom

MAGEB4 MAGEF1 MAGEB10 MAGEC1

2.78e-04361654IPR002190
DomainMAGE

MAGEB4 MAGEF1 MAGEB10 MAGEC1

2.78e-04361654PF01454
DomainANF_lig-bd_rcpt

GRIK1 GRIK2 GRIK5 TAS1R1

3.09e-04371654IPR001828
DomainANF_receptor

GRIK1 GRIK2 GRIK5 TAS1R1

3.09e-04371654PF01094
DomainPeripla_BP_I

GRIK1 GRIK2 GRIK5 TAS1R1

3.80e-04391654IPR028082
DomainPLDc

PLD2 PLD4

4.60e-0441652PF00614
DomainLig_chan-Glu_bd

GRIK1 GRIK2 GRIK5

5.01e-04181653PF10613
DomainGlu/Gly-bd

GRIK1 GRIK2 GRIK5

5.01e-04181653IPR019594
DomainLig_chan-Glu_bd

GRIK1 GRIK2 GRIK5

5.01e-04181653SM00918
DomainIontro_rcpt

GRIK1 GRIK2 GRIK5

5.01e-04181653IPR001320
DomainIono_rcpt_met

GRIK1 GRIK2 GRIK5

5.01e-04181653IPR001508
DomainLig_chan

GRIK1 GRIK2 GRIK5

5.01e-04181653PF00060
DomainPBPe

GRIK1 GRIK2 GRIK5

5.01e-04181653SM00079
DomainSOCS

WSB1 SOCS6 ASB2

6.91e-04201653SM00253
DomainEXPERA

TM6SF2 EBP

7.62e-0451652IPR033118
DomainEXPERA

TM6SF2 EBP

7.62e-0451652PS51751
DomainHEAT

STK36 ATR HEATR4 NCAPD2

8.44e-04481654PF02985
DomainPLDc

PLD2 PLD4

1.14e-0361652SM00155
DomainCarb_sulfotransferase-rel

CHST10 CHST14

1.58e-0371652IPR018011
DomainCupin_4

RIOX1 JMJD8

1.58e-0371652PF08007
DomainPLipase_D/transphosphatidylase

PLD2 PLD4

1.58e-0371652IPR001736
DomainPLD

PLD2 PLD4

1.58e-0371652PS50035
DomainHEAT

STK36 ATR HEATR4 NCAPD2

1.72e-03581654IPR000357
DomainZINC_PROTEASE

TRHDE MMP28 ADAMTS10 MIPEP MMP10

1.78e-03981655PS00142
DomainMetallophos

PPP3CA PPP3CC SMPD1

1.89e-03281653PF00149
DomainCalcineurin-like_PHP_ApaH

PPP3CA PPP3CC SMPD1

1.89e-03281653IPR004843
DomainMetallo-depent_PP-like

PPP3CA PPP3CC SMPD1

2.31e-03301653IPR029052
Domain-

PPP3CA PPP3CC SMPD1

2.31e-033016533.60.21.10
DomainBTK

RASA4 RASA4B

2.68e-0391652SM00107
DomainBEACH

WDR81 WDFY4

2.68e-0391652PS50197
DomainBeach

WDR81 WDFY4

2.68e-0391652PF02138
Domain-

WDR81 WDFY4

2.68e-03916521.10.1540.10
DomainBeach

WDR81 WDFY4

2.68e-0391652SM01026
DomainZnf_Btk_motif

RASA4 RASA4B

2.68e-0391652IPR001562
DomainBEACH_dom

WDR81 WDFY4

2.68e-0391652IPR000409
DomainBTK

RASA4 RASA4B

2.68e-0391652PF00779
DomainZF_BTK

RASA4 RASA4B

2.68e-0391652PS51113
Pubmed

N-glycan content modulates kainate receptor functional properties.

CHST10 GRIK1 GRIK2 GRIK5

9.01e-096174428714086
Pubmed

Short-term plasticity of kainate receptor-mediated EPSCs induced by NMDA receptors at hippocampal mossy fiber synapses.

GRIK1 GRIK2 GRIK5 PPP3CA

2.09e-087174417428973
Pubmed

Effect of RNA editing and subunit co-assembly single-channel properties of recombinant kainate receptors.

GRIK1 GRIK2 GRIK5

1.23e-07317438730589
Pubmed

Distinct roles for the kainate receptor subunits GluR5 and GluR6 in kainate-induced hippocampal gamma oscillations.

GRIK1 GRIK2 GRIK5

1.23e-073174315509753
Pubmed

Transcriptional factor six2 promotes the competitive endogenous RNA network between CYP4Z1 and pseudogene CYP4Z2P responsible for maintaining the stemness of breast cancer cells.

CYP4Z1 SIX6 CYP4Z2P

1.23e-073174330832689
Pubmed

Kainate receptors and rhythmic activity in neuronal networks: hippocampal gamma oscillations as a tool.

GRIK1 GRIK2 GRIK5

4.91e-074174315513934
Pubmed

Kainate receptors act as conditional amplifiers of spike transmission at hippocampal mossy fiber synapses.

GRIK1 GRIK2 GRIK5

4.91e-074174319369569
Pubmed

Distinct subunits in heteromeric kainate receptors mediate ionotropic and metabotropic function at hippocampal mossy fiber synapses.

GRIK1 GRIK2 GRIK5

4.91e-074174316354929
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-10

4.91e-074174310469592
Pubmed

Recurrent DGCR8, DROSHA, and SIX homeodomain mutations in favorable histology Wilms tumors.

SIX1 DROSHA SIX2

4.91e-074174325670082
Pubmed

Localization of glutamate receptors to distal dendrites depends on subunit composition and the kinesin motor protein KIF17.

GRIK1 GRIK2 GRIK5

4.91e-074174317174564
Pubmed

Developmental expression patterns of kainate receptors in the mouse spinal cord.

GRIK1 GRIK2 GRIK5

1.22e-065174323076118
Pubmed

Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma.

LRP12 SIX1 SIX6

1.22e-065174322570617
Pubmed

Evolutionary comparison reveals that diverging CTCF sites are signatures of ancestral topological associating domains borders.

SIX1 SIX6 SIX2

1.22e-065174326034287
Pubmed

Kainate receptors: pharmacology, function and therapeutic potential.

GRIK1 GRIK2 GRIK5

1.22e-065174318793656
Pubmed

Kainate receptor subunits underlying presynaptic regulation of transmitter release in the dorsal horn.

GRIK1 GRIK2 GRIK5

1.22e-065174312223554
Pubmed

Molecular determinants of kainate receptor trafficking.

GRIK1 GRIK2 GRIK5

1.22e-065174318358623
Pubmed

Complete Disruption of the Kainate Receptor Gene Family Results in Corticostriatal Dysfunction in Mice.

GRIK1 GRIK2 GRIK5

1.22e-065174328228252
Pubmed

Development of laminar distributions of kainate receptors in the somatosensory cortex of mice.

GRIK1 GRIK2 GRIK5

1.22e-06517439593973
Pubmed

Mutations in the SIX1/2 pathway and the DROSHA/DGCR8 miRNA microprocessor complex underlie high-risk blastemal type Wilms tumors.

SIX1 DROSHA SIX2

1.22e-065174325670083
Pubmed

Preferential assembly of heteromeric kainate and AMPA receptor amino terminal domains.

GRIK1 GRIK2 GRIK5

1.22e-065174329058671
Pubmed

Characterization of the Six1 homeobox gene in normal mammary gland morphogenesis.

SIX1 SIX6 SIX2

2.43e-066174320074369
Pubmed

The expression profile and clinic significance of the SIX family in non-small cell lung cancer.

SIX1 SIX6 SIX2

2.43e-066174327821176
Pubmed

Dynamic expression of Six family genes in the dental mesenchyme and the epithelial ameloblast stem/progenitor cells during murine tooth development.

SIX1 SIX6 SIX2

2.43e-066174319900183
Pubmed

Glutamate binding and conformational flexibility of ligand-binding domains are critical early determinants of efficient kainate receptor biogenesis.

GRIK1 GRIK2 GRIK5

4.24e-067174319342380
Pubmed

Primary structure and expression of the gamma 2 subunit of the glutamate receptor channel selective for kainate.

GRIK1 GRIK2 GRIK5

4.24e-06717431310861
Pubmed

Six3 and Six6 activity is modulated by members of the groucho family.

SIX1 SIX6 SIX2

6.77e-068174312441302
Pubmed

Pleiotropic effects in Eya3 knockout mice.

SIX1 SIX6 SIX2

1.01e-059174319102749
Pubmed

Splicing and editing of ionotropic glutamate receptors: a comprehensive analysis based on human RNA-Seq data.

GRIK1 GRIK2 GRIK5

1.01e-059174334100982
Pubmed

Expression of glutamate receptor subunit genes during development of the mouse retina.

GRIK1 GRIK2 GRIK5

1.01e-05917439051806
Pubmed

Twenty proteins containing a C-terminal SOCS box form five structural classes.

WSB1 SOCS6 ASB2

1.44e-051017439419338
Pubmed

Altered behavioral responses to noxious stimuli and fear in glutamate receptor 5 (GluR5)- or GluR6-deficient mice.

GRIK1 GRIK2

2.49e-052174215673679
Pubmed

Association of three single nucleotide polymorphisms at the SIX1-SIX6 locus with primary open angle glaucoma in the Chinese population.

SIX1 SIX6

2.49e-052174227260188
Pubmed

Requirement of MTA1 in ATR-mediated DNA damage checkpoint function.

ATR MTA1

2.49e-052174220427275
Pubmed

Kainate receptors are involved in short- and long-term plasticity at mossy fiber synapses in the hippocampus.

GRIK1 GRIK2

2.49e-052174211182092
Pubmed

Age-dependent regional retinal nerve fibre changes in SIX1/SIX6 polymorphism.

SIX1 SIX6

2.49e-052174232719476
Pubmed

Analysis of the mutational status of SIX1/2 and microRNA processing genes in paired primary and relapsed Wilms tumors and association with relapse.

SIX1 SIX2

2.49e-052174233281191
Pubmed

Structure and assembly mechanism for heteromeric kainate receptors.

GRIK2 GRIK5

2.49e-052174221791290
Pubmed

Modulation of excitatory synaptic transmission in the spinal substantia gelatinosa of mice deficient in the kainate receptor GluR5 and/or GluR6 subunit.

GRIK1 GRIK2

2.49e-052174214724198
Pubmed

CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.

RASA4 RASA4B

2.49e-052174211448776
Pubmed

The competing endogenous RNA network of CYP4Z1 and pseudogene CYP4Z2P exerts an anti-apoptotic function in breast cancer.

CYP4Z1 CYP4Z2P

2.49e-052174228236635
Pubmed

The kainate receptor subunit GluR6 mediates metabotropic regulation of the slow and medium AHP currents in mouse hippocampal neurones.

GRIK1 GRIK2

2.49e-052174215539395
Pubmed

Presynaptic localization of GluK5 in rod photoreceptors suggests a novel function of high affinity glutamate receptors in the mammalian retina.

GRIK1 GRIK5

2.49e-052174228235022
Pubmed

Macrophage MMP10 Regulates TLR7-Mediated Tolerance.

TLR7 MMP10

2.49e-052174230564235
Pubmed

RNA editing of human kainate receptor subunits.

GRIK1 GRIK2

2.49e-05217427696618
Pubmed

A comparative analysis of kainate receptor GluK2 and GluK5 knockout mice in a pure genetic background.

GRIK2 GRIK5

2.49e-052174233631192
Pubmed

Expression and novel subunit isoforms of glutamate receptor genes GluR5 and GluR6.

GRIK1 GRIK2

2.49e-05217428260617
Pubmed

Identification of a novel mammary-restricted cytochrome P450, CYP4Z1, with overexpression in breast carcinoma.

CYP4Z1 CYP4Z2P

2.49e-052174215059886
Pubmed

Assessing the role of GLUK5 and GLUK6 at hippocampal mossy fiber synapses.

GRIK1 GRIK2

2.49e-052174215537878
Pubmed

Association of Polymorphisms at the SIX1-SIX6 Locus With Primary Open-Angle Glaucoma.

SIX1 SIX6

2.49e-052174231284308
Pubmed

Postnatal maturation of mossy fibre excitatory transmission in mouse CA3 pyramidal cells: a potential role for kainate receptors.

GRIK1 GRIK2

2.49e-052174215358807
Pubmed

Role of GluK1 kainate receptors in seizures, epileptic discharges, and epileptogenesis.

GRIK1 GRIK2

2.49e-052174224760837
Pubmed

CaMKII-dependent phosphorylation of GluK5 mediates plasticity of kainate receptors.

GRIK1 GRIK5

2.49e-052174223288040
Pubmed

Identification of the kainate receptor subunits underlying modulation of excitatory synaptic transmission in the CA3 region of the hippocampus.

GRIK1 GRIK2

2.49e-052174211069933
Pubmed

Presynaptic kainate receptors impart an associative property to hippocampal mossy fiber long-term potentiation.

GRIK1 GRIK2

2.49e-052174212947409
Pubmed

DNA-binding and regulation mechanisms of the SIX family of retinal determination proteins.

SIX6 SIX2

2.49e-052174218293925
Pubmed

Association of SIX1-SIX6 polymorphisms with peripapillary retinal nerve fibre layer thickness in children.

SIX1 SIX6

2.49e-052174235017159
Pubmed

Association of SIX1/SIX6 locus polymorphisms with regional circumpapillary retinal nerve fibre layer thickness: The Nagahama study.

SIX1 SIX6

2.49e-052174228663559
Pubmed

Kainate receptor-mediated synaptic transmission in the adult anterior cingulate cortex.

GRIK1 GRIK2

2.49e-052174215928066
Pubmed

The 3'UTR of the pseudogene CYP4Z2P promotes tumor angiogenesis in breast cancer by acting as a ceRNA for CYP4Z1.

CYP4Z1 CYP4Z2P

2.49e-052174225701119
Pubmed

Q/R site editing in kainate receptor GluR5 and GluR6 pre-mRNAs requires distant intronic sequences.

GRIK1 GRIK2

2.49e-05217428700852
Pubmed

Q/R site editing controls kainate receptor inhibition by membrane fatty acids.

GRIK1 GRIK2

2.49e-052174216221857
Pubmed

Altered long-term synaptic plasticity and kainate-induced Ca2+ transients in the substantia gelatinosa neurons in GLU(K6)-deficient mice.

GRIK1 GRIK2

2.49e-052174216219388
Pubmed

Ligand binding is a critical requirement for plasma membrane expression of heteromeric kainate receptors.

GRIK2 GRIK5

2.49e-052174215583001
Pubmed

Lack of association between SIX1/SIX6 locus polymorphisms and pseudoexfoliation syndrome in a population from the Republic of Korea.

SIX1 SIX6

2.49e-052174236596020
Pubmed

Association of Polymorphisms at the SIX1/SIX6 Locus With Normal Tension Glaucoma in a Korean Population.

SIX1 SIX6

2.49e-052174235658088
Pubmed

Subunit composition and alternative splicing regulate membrane delivery of kainate receptors.

GRIK1 GRIK2

2.49e-052174215014126
Pubmed

Trafficking and surface expression of the glutamate receptor subunit, KA2.

GRIK2 GRIK5

2.49e-052174214511640
Pubmed

Subunit composition of kainate receptors in hippocampal interneurons.

GRIK1 GRIK2

2.49e-052174211144357
Pubmed

Contribution of aberrant GluK2-containing kainate receptors to chronic seizures in temporal lobe epilepsy.

GRIK1 GRIK2

2.49e-052174225043179
Pubmed

Polymorphism rs10483727 in the SIX1/SIX6 Gene Locus Is a Risk Factor for Primary Open Angle Glaucoma in a Saudi Cohort.

SIX1 SIX6

2.49e-052174229190129
Pubmed

A mosaic of functional kainate receptors in hippocampal interneurons.

GRIK1 GRIK2

2.49e-052174215483117
Pubmed

Functional characterization of kainate receptors in the mouse nucleus accumbens.

GRIK1 GRIK2

2.49e-052174211985817
Pubmed

An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.

RASA4 RASA4B

2.49e-052174216041389
Pubmed

Selective block of postsynaptic kainate receptors reveals their function at hippocampal mossy fiber synapses.

GRIK2 GRIK5

2.49e-052174222345355
Pubmed

Chromosomal anomalies at 1q, 3, 16q, and mutations of SIX1 and DROSHA genes underlie Wilms tumor recurrences.

SIX1 DROSHA

2.49e-052174226802027
Pubmed

SPAG4L/SPAG4Lβ interacts with Nesprin2 to participate in the meiosis of spermatogenesis.

SPAG4 SYNE2

2.49e-052174231144711
Pubmed

ALK phosphorylates SMAD4 on tyrosine to disable TGF-β tumour suppressor functions.

ALK SMAD4

2.49e-052174230664791
Pubmed

Distribution of kainate receptor subunit mRNAs in human hippocampus, neocortex and cerebellum, and bilateral reduction of hippocampal GluR6 and KA2 transcripts in schizophrenia.

GRIK2 GRIK5

2.49e-05217429099808
Pubmed

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.

DENND2A DENND2B DENND4B DENND2C

3.51e-0537174420937701
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

SNF8 DNAJC4 EPS8L2 TUT4 PFAS PAQR6 TUBGCP2 ADAMTS10 GCLC DROSHA OSBPL7 HACL1 SMPD1 RABGGTA SMAD4

6.96e-059251741528986522
Pubmed

Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor.

RNF213 ALK

7.44e-053174212112524
Pubmed

CD28 inhibits T cell adhesion by recruiting CAPRI to the plasma membrane.

RASA4 RASA4B

7.44e-053174225637021
Pubmed

Distinct Subunit Domains Govern Synaptic Stability and Specificity of the Kainate Receptor.

GRIK1 GRIK2

7.44e-053174227346345
Pubmed

Cloning and functional expression of a cDNA encoding the mouse beta 2 subunit of the kainate-selective glutamate receptor channel.

GRIK1 GRIK2

7.44e-05317421379666
Pubmed

Cloning and characterization of molecular isoforms of the catalytic subunit of calcineurin using nonisotopic methods.

PPP3CA PPP3CC

7.44e-05317422162844
Pubmed

Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.

ERVK-6 ERVK-11

7.44e-05317429971820
Pubmed

The kainate receptor antagonist UBP310 but not single deletion of GluK1, GluK2, or GluK3 subunits, inhibits MPTP-induced degeneration in the mouse midbrain.

GRIK1 GRIK2

7.44e-053174231513786
Pubmed

Genetic association of SNPs near ATOH7, CARD10, CDKN2B, CDC7 and SIX1/SIX6 with the endophenotypes of primary open angle glaucoma in Indian population.

SIX1 SIX6

7.44e-053174225798827
Pubmed

The proline-rich N-terminal sequence of calcineurin Abeta determines substrate binding.

PPP3CA PPP3CC

7.44e-053174219154138
Pubmed

RNA editing of the glutamate receptor subunits GluR2 and GluR6 in human brain tissue.

GRIK1 GRIK2

7.44e-05317427523595
Pubmed

Homeostatic control of synaptic transmission by distinct glutamate receptors.

GRIK1 GRIK5

7.44e-053174223719165
Pubmed

Molecular effects of Eya1 domain mutations causing organ defects in BOR syndrome.

SIX1 SIX2

7.44e-053174211734542
Pubmed

Kainate receptor-mediated responses in the CA1 field of wild-type and GluR6-deficient mice.

GRIK1 GRIK2

7.44e-05317429880586
Pubmed

ALK-mediated Tyr95 phosphorylation of Smad4 impairs its transcription activity and the tumor suppressive activity of TGF-β.

ALK SMAD4

7.44e-053174230820854
Pubmed

Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss.

SIX1 SIX2

7.44e-053174215735644
Pubmed

Spatiotemporal expression patterns of mammalian chordin during postgastrulation embryogenesis and in postnatal brain.

GDF10 CHRD

7.44e-053174210767089
Pubmed

Differential trafficking of GluR7 kainate receptor subunit splice variants.

GRIK1 GRIK2

7.44e-053174215805114
Pubmed

Genetic variants in microRNA and microRNA biogenesis pathway genes and breast cancer risk among women of African ancestry.

TUT4 DROSHA

7.44e-053174227380242
Pubmed

Aberrant expression of ALK and EZH2 in Merkel cell carcinoma.

ERBB4 ALK

7.44e-053174228359267
GeneFamilyGlutamate ionotropic receptor kainate type subunits

GRIK1 GRIK2 GRIK5

1.78e-06510331199
GeneFamilySINE class homeoboxes

SIX1 SIX6 SIX2

3.55e-0661033525
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

DENND2A DENND2B DENND4B DENND2C

1.15e-05251034504
GeneFamilyMAGE family

MAGEB4 MAGEF1 MAGEB10 MAGEC1

7.75e-054010341136
GeneFamilyWD repeat domain containing|BEACH domain containing

WDR81 WDFY4

1.13e-03910321230
GeneFamilyPleckstrin homology domain containing|SH2 domain containing|C2 and RasGAP domain containing

RASA4 RASA4B

1.40e-03101032830
GeneFamilyProtein phosphatase catalytic subunits|EF-hand domain containing

PPP3CA PPP3CC

2.41e-03131032693
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPAG4 IRF4 MANEA PPP3CC DENND2C ASB2 CHPF HERPUD1

4.92e-071821698626aabfd9ac662c1d189f7c4b660482914d9e669
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPAG4 IRF4 MANEA PPP3CC DENND2C ASB2 CHPF HERPUD1

4.92e-071821698a00abff41c12b71d5860c494b8c722d649fd5f36
ToppCelldistal-1-Hematologic-Plasma|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SPAG4 RALGPS2 IRF4 MANEA PAQR6 CHPF UNC79 HERPUD1

8.95e-071971698f5499bfa9dbc111f12563b7006bc45c2423ad0cd
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Neuronal-Intermediate|GW08 / Sample Type, Dataset, Time_group, and Cell type.

CYP11A1 PANX1 PAQR6 DUS1L FUT11 DDHD1 RHBDL3 MIPEP

1.00e-062001698401d50fa394fa863fa7836344110ae5c7af3250a
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETD6 IRF4 PRSS36 ZUP1 DUS1L YLPM1 ZMAT1

2.47e-0615816971d78578dc1f8ba43dacdccae1082c0b9d749f64d
ToppCellIIH-CD8-naive_CD4|IIH / Condition, Cell_class and T cell subcluster

IL11RA EARS2 WDR81 IRF4 PPCS GCLC OSBPL7

4.49e-0617316974f2843371d18af766c1892529ce286f56c956fde
ToppCellControl-Myeloid-pDC|Control / Disease state, Lineage and Cell class

CTC1 SEMA5A IRF4 PFAS RHEX AUTS2 PLD4

5.22e-0617716973940663bb5b45b2ca9f772550380a516c53e410b
ToppCellCOPD-Lymphoid-B_Plasma|COPD / Disease state, Lineage and Cell class

SPAG4 RALGPS2 IRF4 PFAS RHEX CHPF HERPUD1

5.22e-0617716971b872d3b1e0fca138362098590a634d748dfca60
ToppCellwk_15-18-Epithelial-PNS-COL20A1+_Schwann|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ERBB4 GRIK1 GRIK2 PAQR6 TAS1R1 EGFLAM UNC79

5.22e-061771697b8cc6a7abf83a9844a5293b6cc4b19135b51fd53
ToppCellControl-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

CTC1 SEMA5A IRF4 PFAS RHEX AUTS2 PLD4

5.22e-061771697e82115bfc32c7b689460fbc5caeb983c1aabe30f
ToppCellControl-Myeloid-pDC|World / Disease state, Lineage and Cell class

CTC1 SEMA5A IRF4 PFAS RHEX AUTS2 PLD4

5.42e-06178169720ef63d925e67ddd5955832312ca8574a6f838a4
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE STK36 PKD1L2 SLC24A2 USH2A UNC79 CNTN2

6.73e-0618416972cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE STK36 PKD1L2 SLC24A2 USH2A UNC79 CNTN2

6.73e-061841697ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell10x5'-blood-Myeloid_Dendritic-DC1|blood / Manually curated celltypes from each tissue

WDFY4 DENND2B PM20D2 RHEX G6PC3 MIPEP ASB2

6.73e-06184169709fa465d1852b9b7e0405c27d4e5de276c9ba871
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRHDE STK36 PKD1L2 SLC24A2 USH2A UNC79 CNTN2

6.73e-0618416972b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPAG4 IRF4 MANEA DENND2C PTCH2 CHPF HERPUD1

6.97e-061851697ff598af88c7f9d7224cc4ed96b1c3463ef76b550
ToppCellCOVID-19_Mild-pDC|COVID-19_Mild / Disease condition and Cell class

EPS8L2 SEMA5A IRF4 RHEX AUTS2 CHPF PLD4

7.75e-06188169762d33d2990d4a2d32bd0863147e47f656df1966e
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPAG4 IRF4 MANEA PAQR6 PTCH2 CHPF HERPUD1

7.75e-061881697fd4d304f1cb41e694d21b5441739eb34a5a13b04
ToppCellCOVID-19_Mild-pDC-|COVID-19_Mild / Disease condition and Cell class

EPS8L2 SEMA5A IRF4 RHEX AUTS2 CHPF PLD4

7.75e-061881697a75c2cf2f8dae343c13aaa66b637658b935ed10a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE DENND2A RALGPS2 ERMP1 RHEX SYNE2 PLEKHH2

8.59e-061911697d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRHDE DENND2A ERBB4 RNF213 RHEX SYNE2 PLEKHH2

9.51e-061941697e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DNAJC4 ERBB4 CHST14 DENND2B PRSS36 AUTS2 MMP10

1.02e-051961697ed76eeb37400ca154feae9b7ebaddb6c434f8b81
ToppCelldistal-Hematologic-Plasma-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SPAG4 RALGPS2 MANEA PAQR6 CHPF UNC79 HERPUD1

1.02e-0519616978201aded3c7109fae5e6ca12bac2076acc7bf070
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RGPD2 SPAG4 RALGPS2 IRF4 MANEA WDFY4 HERPUD1

1.12e-0519916971bb02f41f3cc76a28581e38b0ca4c36b930b85b4
ToppCellLPS-IL1RA-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CYP11A1 HEATR4 IRF4 TLR7 SLC38A8 PLD4

2.26e-051491696a464c0fd54e3c9e1d40d95b49489cb9371dd7c24
ToppCellLPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-pDC|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IRF4 PANX1 PAQR6 TLR7 WDFY4 PLD4

2.53e-0515216960c6dd41142e4ca1e54ca41e05e42ed29fbf0e570
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ERBB4 SEMA5A GRIK1 GRIK2 GDF10 ALK

3.04e-051571696516903469756c5fabfdf56d7bd59b3bdd7b44e39
ToppCelltumor_Lymph_Node_/_Brain-B_lymphocytes-MALT_B_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

RGPD2 SPAG4 IRF4 TAS1R1 CHPF HERPUD1

3.26e-051591696204e5a675f4684c9570c24c8d34bbf632fd8164a
ToppCellLAM-Lymphoid-B-cell-2|LAM / Condition, Lineage and Cell class

SPAG4 RALGPS2 MANEA PAQR6 CHPF HERPUD1

3.38e-0516016960060c2b3304f411c682aa2ba20bcf80f346d2403
ToppCellChildren_(3_yrs)-Immune-dendritic_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

IRF4 TLR7 WDFY4 RHEX LOXL2 PLD4

3.62e-05162169686a0b9dabd150dc993bfc0f3344804de7f8e4042
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ERBB4 SEMA5A GRIK1 GRIK2 GDF10 ALK

3.75e-0516316968d17f44faf0549fe71a9a45f811f50d767275414
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LRP12 ERBB4 SEMA5A GRIK1 GDF10 ALK

3.88e-05164169608819970174a3eb4eee8e1e675075828665b845e
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP11A1 SGPP2 RALGPS2 WDFY4 ALK PLD4

4.01e-05165169636415924d05373e9dd3665be599f4f3f40bf0497
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

IRF4 WDFY4 RHEX CACNA2D4 LOXL2 ASB2

4.01e-051651696d8b0a9b6f704b98e8f0412c11739879a26c036e2
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP11A1 SGPP2 RALGPS2 WDFY4 ALK PLD4

4.01e-05165169656310fddd3d8e4afdfde066d26cee9747e5b8c6a
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells-IgG_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPAG4 IRF4 MANEA TAS1R1 CHPF HERPUD1

4.01e-0516516969e2fa634f4749e35aa5dca43476477b5d362afd7
ToppCellNS-control-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IRF4 PAQR6 TLR7 WDFY4 RHEX PLD4

4.01e-0516516968b2d43d7c4ee07bd999bd51bc15117ce1fbb2d86
ToppCellNS-critical-d_07-13-Myeloid-pDC|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IRF4 TLR7 WDFY4 RHEX HERPUD1 PLD4

4.01e-05165169617d5c4a111d9b5400780bc5e7b93ce2f5d69ceb7
ToppCellcontrol-Myeloid-pDC|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

IRF4 PAQR6 TLR7 WDFY4 RHEX PLD4

4.01e-051651696243c74adf8d993ff92acbff2768bdc5a1693eca3
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DENND2A SEMA5A GCLC RASA4 CHRD EGFLAM

4.15e-051661696bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DENND2A SEMA5A GCLC RASA4 CHRD EGFLAM

4.15e-0516616965e3b998d740b24f790fad37350d704ca0ea10b77
ToppCell368C-Myeloid-Dendritic-pDC|368C / Donor, Lineage, Cell class and subclass (all cells)

IRF4 PFAS TLR7 RPAP1 RASA4B PLD4

4.29e-0516716961e2fc1637769405a61f4c7e44945712a1888a299
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TRHDE ERBB4 GRIK2 PAQR6 EGFLAM ALK

4.29e-05167169649b19159c62d33d65ed1e59a148c11ae902fd41c
ToppCellNS-moderate-d_07-13-Myeloid-pDC|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAJC4 IRF4 TLR7 RHEX HERPUD1 PLD4

4.44e-051681696d03e91f0e0518b33555c0ec98124fc5ed0f11be5
ToppCell3'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CTC1 IRF4 ZUP1 RHEX HERPUD1 PLD4

4.74e-051701696db0ec8b7ecbb4db108fc35c564df4b740f65cc8f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ERBB4 EPS8L2 TLR7 SYNE2 AUTS2 C4BPA

4.74e-051701696a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell3'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CTC1 IRF4 ZUP1 RHEX HERPUD1 PLD4

4.74e-05170169688f6804e973863245ca1c7e5e6656d4a8b824da9
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IRF4 TLR7 WDFY4 RHEX HERPUD1 PLD4

4.74e-05170169692e765ae0d3adb38d3b22fddb873fd5ccad3fd44
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IRF4 TLR7 WDFY4 RHEX HERPUD1 PLD4

4.74e-0517016969f8b215caa1afa3cd7104c06fca7cfd790640f66
ToppCell3'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CTC1 IRF4 ZUP1 RHEX HERPUD1 PLD4

4.74e-051701696dad3aaf7d9f7bafdbddee51610f03f2359e587ae
ToppCellnormal-na-Lymphocytic_B-B_plasma-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

IRF4 MANEA PAQR6 DENND2C ASB2 CHPF

4.74e-051701696c5b87974dfddf9780051f7f5693eeeb0c606a3fe
ToppCell368C-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

IRF4 PFAS RPAP1 RASA4B DSEL PLD4

4.90e-051711696714a0b0d0c9886fef64170cf53eb64f0d8a47280
ToppCellInt-URO-Lymphocyte-T_NK-dnT|Int-URO / Disease, Lineage and Cell Type

IL11RA ZNF430 RPAP1 PTPRF OSBPL7 PPP1R3F

5.06e-051721696e70299573da1679d6d286c3a43699cbff76e207d
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND2A CHST14 GRIK2 GDF10 RHBDL3 PLEKHH2

5.06e-051721696073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCellControl-Lymphoid-B_Plasma|Control / Disease state, Lineage and Cell class

SPAG4 RALGPS2 IRF4 PFAS RHEX CHPF

5.06e-05172169661e33836b8cb0f347f3e699eb587a37073b6fa4c
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA5A DENND2B LOXL2 RHBDL3 PLEKHH2 ALK

5.39e-051741696f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RALGPS2 WDFY4 RHEX PPP3CC HERPUD1 PLD4

5.39e-051741696ebe6ce173ad12d4a2afa39f8d6185c0e4f97fb1e
ToppCellCOPD-Myeloid-pDC|World / Disease state, Lineage and Cell class

CTC1 IRF4 PFAS RHEX AUTS2 PLD4

5.39e-051741696be8227398300711ccda5ecc41ad34064bb246b19
ToppCellIPF-Myeloid-pDC|World / Disease state, Lineage and Cell class

CTC1 IRF4 PFAS RHEX AUTS2 PLD4

5.57e-051751696a06785a4ded01adfd29ca4c20f7759eccbe274cb
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

RGPD2 AOC1 CYP11A1 TNIP1 RHEX ASB2

5.75e-051761696581d78811b2d99f38a2c7cc268aeb1cf932379c2
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

WSB1 ERBB4 SGPP2 GRIK2 SIX1 SLC26A8

5.75e-0517616963bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCellFetal_29-31_weeks-Immune-dendritic_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

IRF4 WDFY4 RHEX LOXL2 ASB2 PLD4

5.93e-051771696c5e829bc4594761666d65cace5a9c5d19c16f187
ToppCellCOPD-Myeloid-pDC|COPD / Disease state, Lineage and Cell class

CTC1 IRF4 PFAS RHEX AUTS2 PLD4

5.93e-051771696415aa023195a7f961c09529f65cdcc7bb90eaf5d
ToppCellIPF-Myeloid-pDC|IPF / Disease state, Lineage and Cell class

CTC1 IRF4 PFAS RHEX AUTS2 PLD4

6.12e-0517816968d9e28492e1f157bac3308aa947fd864ca16d277
ToppCell10x3'2.3-week_17-19-Lymphocytic_T-T_NK-NK_T_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

EPS8L2 SOX30 ALS2CL ADAMTS10 RASA4B SMPD1

6.12e-051781696a34bb693b72684cbd97ac9efff77d2d14e41be75
ToppCellASK440-Epithelial-Transformed_epithelium|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

TRHDE CYP4Z1 EARS2 KLHL35 GDF10 ZNF24

6.12e-05178169686f1741636ed3e85bb4a65f84949b718fc38c290
ToppCellCOPD-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

CTC1 IRF4 PFAS RHEX AUTS2 PLD4

6.31e-05179169629b058c5e33fda9f0d738c074bdb67ff16b9b6d5
ToppCellBLOOD--(5)_Plasma| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SPAG4 IRF4 MANEA PAQR6 RHEX CHPF

6.51e-0518016961ac0a0a715f4a36df0762bb0de44802d6ffa284c
ToppCellmoderate-Myeloid-pDC|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

IRF4 TLR7 WDFY4 RHEX HERPUD1 PLD4

6.51e-051801696a0751ad5e42a21cb107d900abfa9ee967a0069fc
ToppCellBLOOD--(5)_Plasmablasts| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SPAG4 IRF4 MANEA PAQR6 RHEX CHPF

6.51e-0518016964b9be1b19d4ecd0a3b924e4557a1ecfbcff2d705
ToppCellNS-moderate-d_16-33-Myeloid-pDC|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IRF4 TLR7 WDFY4 RHEX HERPUD1 PLD4

6.51e-051801696144818e69613296cde43f29cb8c20899c670b319
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST14 RPAP1 JMJD7 GCLC DDHD1 PPP1R3F

6.51e-051801696be10fe5bf7c3a671c42704ce7dd8226ab6896794
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST14 RPAP1 JMJD7 GCLC DDHD1 PPP1R3F

6.51e-0518016963b747a517ce75ef2ff09011c037dad7b01ed3e03
ToppCell10x5'-GI_small-bowel-Lymphocytic_B_plasma|GI_small-bowel / Manually curated celltypes from each tissue

SPAG4 RALGPS2 IRF4 MANEA CHPF HERPUD1

6.71e-0518116969b33f531c8ac776706ec7e2d47e95ba30b6ce13c
ToppCellSevere-Lymphoid-pDC|Severe / Condition, Lineage, Cell class and cell subclass

IRF4 TLR7 WDFY4 RHEX HERPUD1 PLD4

6.71e-0518116962caecb7c5dcdad46fd02b4ffb73cb613ce835187
ToppCell10x3'2.3-week_12-13-Mesenchymal_myocytic|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TRHDE SIX1 TM6SF2 GDF10 DQX1 EGFLAM

6.71e-05181169647dce04db3392333eb2f7b9b24c32e6740d2d02f
ToppCell10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TRHDE SIX1 TM6SF2 GDF10 DQX1 EGFLAM

6.71e-05181169619103221c3a5a16b16378348004b2c50caee4f01
ToppCell10x5'-GI_small-bowel-Lymphocytic_B_plasma-Plasma_cells|GI_small-bowel / Manually curated celltypes from each tissue

SPAG4 RALGPS2 IRF4 MANEA CHPF HERPUD1

6.71e-051811696a0549a8c2b5b30e91fae3052f398e48baa45d7ff
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD1c+_DCs|Myeloid_cells / Location, Cell class and cell subclass

DNAJC4 MPC2 C4BPA ASB2 HERPUD1 PLD4

6.71e-051811696cc7ae1221a28bc404138a7efee0ad08a19cc3d86
ToppCellSevere-Lymphoid-pDC-|Severe / Condition, Lineage, Cell class and cell subclass

IRF4 TLR7 WDFY4 RHEX HERPUD1 PLD4

6.71e-051811696277ce4c49121da0990a5933b19d2c6af9bbe253e
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_SCP_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TRHDE ERBB4 GRIK2 PAQR6 EGFLAM ALK

6.71e-051811696fad7ba168f541ac9d04edebc206f191e48bb7e99
ToppCellCOPD-Epithelial-ATI|World / Disease state, Lineage and Cell class

EPS8L2 CYP4Z1 SEMA5A ALS2CL CYP4Z2P PTPRF

6.92e-051821696e95d946a43b1579af199900bb0e3eacbb9d65300
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUT4 RALGPS2 GDF10 PM20D2 RASA4 NCAPD2

6.92e-0518216969174fb0b7ed8f721a5c513e41fd80476a9f34332
ToppCellCOPD-Epithelial-Basal|COPD / Disease state, Lineage and Cell class

CYP4Z1 SGPP2 SEMA5A CYP4Z2P DENND2C MMP10

7.13e-0518316960f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCellCOVID-19-B_cells-Plasma_cells|COVID-19 / group, cell type (main and fine annotations)

SPAG4 RALGPS2 IRF4 MANEA RHEX HERPUD1

7.13e-051831696130c109f63a5e3c8f83cb96e32f4addf513b6415
ToppCellCOVID-19-B_cells|COVID-19 / group, cell type (main and fine annotations)

SPAG4 RALGPS2 IRF4 MANEA RHEX HERPUD1

7.13e-0518316962c016bb59f131a0e821853b085289a3583f0a729
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPAG4 IRF4 MANEA DENND2C CHPF HERPUD1

7.13e-051831696c5e90577b57a86c06afdf89d4b519b3694f813f9
ToppCellControl-Epithelial-ATI|World / Disease state, Lineage and Cell class

EPS8L2 MMP28 SEMA5A ALS2CL CYP4Z2P PTPRF

7.57e-0518516960563d5042bb96ecce8446fbf26d05ef7a45e23c5
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

TRPM7 RNF213 ERMP1 RASA4 DDHD1 DENND4B

7.57e-051851696a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Plasma_cells|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SPAG4 IRF4 MANEA DENND2C CHPF HERPUD1

7.57e-051851696a4792d8df52d80951fb9d022c49821df52100e67
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP47 CFAP107 ERBB4 WFDC6 NEK5 AGBL2

7.57e-0518516965e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TRHDE ERBB4 GRIK2 PAQR6 EGFLAM ALK

7.57e-05185169656c7a0dbf141728ac76b8c90af197719942ca67c
ToppCellCF-Myeloid-cDC|CF / Disease state, Lineage and Cell class

MPC2 IRF4 LOXL2 AUTS2 PDGFC PLD4

7.57e-0518516967f3d118845ff9f5f525796b0bbc6532a8ee323ab
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IRF4 TLR7 WDFY4 RHEX HERPUD1 PLD4

7.80e-0518616960096a61b1841784c913752b4f3639200446cc02c
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IRF4 TLR7 WDFY4 RHEX HERPUD1 PLD4

7.80e-0518616966345777847960c71a2ba3ce5a49c72c34ebd0e73
ToppCellhealthy_donor-Lymphocytic-Dendritic|healthy_donor / Disease condition, Lineage, Cell class and subclass

SEMA5A IRF4 TLR7 WDFY4 RHEX PLD4

7.80e-051861696916f2aeea4989ba7a29e071e348a51010f010223
ToppCellcellseq-Immune-Immune_Myeloid-Myeloid_Dendritic-pDC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IRF4 TLR7 WDFY4 RHEX HERPUD1 PLD4

7.80e-051861696d23c3318937492d7d665bec14253124c49181b5a
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IRF4 TLR7 WDFY4 RHEX HERPUD1 PLD4

7.80e-0518616969e159ad7289dcae2ec7ce655df746f46801b81d3
ToppCellCOPD-Epithelial-ATI|COPD / Disease state, Lineage and Cell class

EPS8L2 CYP4Z1 SEMA5A ALS2CL CYP4Z2P PTPRF

7.80e-051861696df0977f6f48a2d4e11b59971f098b01204242f0f
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TRHDE ERBB4 GRIK2 PAQR6 EGFLAM ALK

7.80e-0518616963113c85d0ac5fc46532c19b1bb71f34b985e1276
Diseaseserum metabolite measurement

AOC1 HEATR4 SGPP2 GRIK2 ERMP1 GRIK5 PKD1L2 TM6SF2 PM20D2 CYP4Z2P MTA1 NTAN1 PPP3CA SYNE2 MIPEP HERPUD1 ALK

1.89e-0594516217EFO_0005653
Diseasealcohol use disorder (implicated_via_orthology)

ERBB4 EPS8L2 RIOX1 JMJD7 RHBDL3 AUTS2 UNC79

1.06e-041951627DOID:1574 (implicated_via_orthology)
Diseasesurvival time, pneumonia, septic shock, Sepsis

GRIK2 GRIK5

1.78e-0441622EFO_0000714, EFO_0003106, EFO_0006834, HP_0100806
Diseasedodecenedioate (C12:1-DC) measurement

HEATR4 CYP4Z2P

1.78e-0441622EFO_0800561
DiseaseOvarian Serous Adenocarcinoma

STK36 TRPM7 ALK

2.65e-04231623C1335177
Diseasemetabolite measurement

AOC1 HEATR4 SLC17A4 PKD1L2 WDFY4 PM20D2 CYP4Z2P SYNE2 YLPM1 ASB2 PLEKHH2

2.83e-0456016211EFO_0004725
DiseaseX-24020 measurement

AOC1 TUBGCP2

2.96e-0451622EFO_0022128
Disease3-hydroxysebacate measurement

SLC17A4 CYP4Z2P

2.96e-0451622EFO_0800205
Disease2-hydroxysebacate measurement

CYP4Z2P HACL1

2.96e-0451622EFO_0800571
Diseasecarbamazepine metabolite measurement

GRIK2 GRIK5

4.43e-0461622EFO_0009891
DiseaseBilateral Wilms Tumor

SIX1 DROSHA SIX2

5.34e-04291623C2930471
Diseasesynophrys measurement

IRF4 MTX2 AUTS2 HAND1

5.42e-04681624EFO_0007906
Diseaselevel of oxylipin in blood plasma

GRIK2 GRIK5

6.18e-0471622OBA_2050338
Disease10-undecenoate 11:1n1 measurement

CYP4Z1 CYP4Z2P

6.18e-0471622EFO_0021099
DiseaseX-24748 measurement

HEATR4 CYP4Z2P

8.21e-0481622EFO_0022136
Diseasepseudouridine measurement

GRIK2 GRIK5

8.21e-0481622EFO_0021126
Diseasecolorectal health

LRP12 SEMA5A GRIK2 GRIK5 AUTS2 ANKS1A

8.79e-042011626EFO_0008460
Diseaselifestyle measurement, anxiety disorder measurement

TRHDE GRIK2 GRIK5 USH2A SIX2

9.78e-041371625EFO_0007795, EFO_0010724
DiseaseNephroblastoma

SIX1 DROSHA SIX2

1.02e-03361623C0027708
DiseaseCombined oxidative phosphorylation deficiency

EARS2 MRPL44 MIPEP

1.10e-03371623cv:C4540031
DiseaseSchizophrenia

ERBB4 GRIK1 GRIK2 GRIK5 ALS2CL SLC26A8 PPP3CC GCLC ERVK-8 AUTS2 DIXDC1 MAGEC1 ALK

1.22e-0388316213C0036341
Disease2-ketocaprylate measurement

HEATR4 HACL1

1.31e-03101622EFO_0800110
Disease1,7-dimethylurate measurement

GRIK2 GRIK5

1.31e-03101622EFO_0021512
Diseasecocaine use

CYP11A1 GRIK1

1.59e-03111622C3496069
DiseaseX-21607 measurement

HEATR4 CYP4Z2P

1.59e-03111622EFO_0800819
Diseaselevel of Ceramide (d40:1) in blood serum

TM6SF2 SYNE2

1.59e-03111622OBA_2045185
Diseaseserum albumin measurement

AOC1 CYP11A1 WDR81 IRF4 GRIK2 GRIK5 TM6SF2 MIPEP ASB2 PDGFC

1.67e-0359216210EFO_0004535
Diseasenon-alcoholic steatohepatitis

TM6SF2 C1orf94

1.91e-03121622EFO_1001249
Diseaseundecenoylcarnitine (C11:1) measurement

HEATR4 CYP4Z2P

2.25e-03131622EFO_0800588
Disease3-carboxy-4-methyl-5-propyl-2-furanpropanoate CMPF measurement

GRIK2 GRIK5

2.25e-03131622EFO_0021053
Diseasegastroesophageal reflux disease

ERBB4 PPP3CA YLPM1 UNC79

2.36e-031011624EFO_0003948
DiseaseBell's palsy

ERBB4 GRIK2 GRIK5 C4BPA

2.45e-031021624EFO_0007167
Diseaseglycodeoxycholate measurement

GRIK2 GRIK5

2.61e-03141622EFO_0010493
Diseasetriacylglycerol 50:5 measurement

TM6SF2 CACNA2D4

3.42e-03161622EFO_0010412
Diseasenervousness

YLPM1 AGBL2

3.42e-03161622NCIT_C74532
Diseaseeicosapentaenoate EPA; 20:5n3 measurement

GRIK2 GRIK5

3.86e-03171622EFO_0021049
Diseaselevel of Sphingomyelin (d32:1) in blood serum

ERMP1 SYNE2

3.86e-03171622OBA_2045173
Diseaseblood osmolality measurement

GRIK2 GRIK5 PKD1L2

4.02e-03581623EFO_0007967
Diseaselevel of Phosphatidylcholine (15:0_18:2) in blood serum

NTAN1 HERPUD1

4.33e-03181622OBA_2045065
DiseasePancreatic carcinoma

ALOX12B SMAD4

4.82e-03191622C0235974
Diseaselevel of Sterol ester (27:1/20:3) in blood serum

TM6SF2 NTAN1

4.82e-03191622OBA_2045199
Diseaseinferior parietal cortex volume measurement

GRIK1 DENND2B

4.82e-03191622EFO_0010307
Diseasecolorectal cancer, inflammatory bowel disease

GRIK2 GRIK5

4.82e-03191622EFO_0003767, MONDO_0005575
Diseasephosphatidylcholine measurement

GRIK2 GRIK5 TM6SF2 NTAN1 SYNE2 HERPUD1

4.94e-032841626EFO_0010226
Diseaserenal system measurement

GRIK2 GRIK5

5.33e-03201622EFO_0004742
Diseaseresponse to heparin, antibody measurement

GRIK2 GRIK5

5.33e-03201622EFO_0004556, EFO_0006816
Diseaselevel of Phosphatidylcholine (16:0_18:2) in blood serum

NTAN1 HERPUD1

5.33e-03201622OBA_2045071

Protein segments in the cluster

PeptideGeneStartEntry
FLPWHAASRALYPLD

TRHDE

751

Q9UKU6
PNLEPSWPHLQLVYE

PPP2R5B

156

Q15173
PQAPQPFRYTGHWER

ALS2CL

451

Q60I27
HFSQPPYRDLWEPPR

CCDC185

6

Q8N715
NLPDIPHASWETYPR

C4BPA

301

P04003
RAMHLFPAPPAHWFY

CYP4Z2P

41

Q8N1L4
AFDNPDYWNHSLPPR

ERBB4

1236

Q15303
LRSYAATPWPLEPQH

EGFLAM

616

Q63HQ2
HLFLFPRWSYLPPAR

CTC1

156

Q2NKJ3
FSHPISAHLPWYFQP

ACR

316

P10323
PPFIEGNHSSRWLYE

SMPD1

331

P17405
PAHFYPWTRSTAPPE

ASB2

61

Q96Q27
EYRESWPPNSKLPHS

DIXDC1

576

Q155Q3
IARFTPYEWYNPHPC

GRIK1

596

P39086
GDLPFHWICQPYIRP

DUS1L

326

Q6P1R4
PSLAAPYAPVQSWQH

ANKS1A

916

Q92625
PCALGPFPRYIWIHQ

C1orf94

41

Q6P1W5
PFPRYIWIHQDTPQD

C1orf94

46

Q6P1W5
SIYHQNDPWHPPVVF

AOC1

636

P19801
YPFSWQHTFIPVLPA

DENND2B

921

P78524
PVHFLIRKNWYLPAP

ERMP1

751

Q7Z2K6
NAPIARDSLPPYSWH

ADAMTS10

816

Q9H324
PFWGEEYQVHLPPTF

RASA4

51

O43374
PFWGEEYQVHLPPTF

RASA4B

51

C9J798
ARLNWILHFGLPPRY

HACL1

281

Q9UJ83
YLHHVGWFPFRPRPV

HERPUD1

301

Q15011
LYNHPAGPRTVFFWA

MPC2

31

O95563
PRFPHTYPRNTVLVW

PDGFC

61

Q9NRA1
PEPEFHLISAFWPSL

MMP10

321

P09238
WFHGPSLTRPPNYFE

OGFOD1

236

Q8N543
FRLQYRPAQHPAWST

IL11RA

256

Q14626
PFYDLWASDNPLDRP

NOP53

191

Q9NZM5
IPPPYISSQDHIWIR

LRP12

126

Q9Y561
PRYQFLWGPRAHAET

MAGEB4

266

O15481
SDPPRYQFLWGPRAH

MAGEB10

266

Q96LZ2
LPEWEDSLSPHYFPQ

MAGEC1

536

O60732
HTNPPEYEFSWGPRS

MAGEF1

231

Q9HAY2
PLVPPRTIQHKYTNW

MBTD1

241

Q05BQ5
RSWRDYVPDQPHPEI

IRF4

176

Q15306
PTPLHFYRDWVCPNR

JMJD7

36

P0C870
RWIHPPSGRVYNLDF

AK4

126

P27144
PLDWLGHPPQISLFY

G6PC3

296

Q9BUM1
PLSLAQYDSWPHYPE

LOXL2

21

Q9Y4K0
ATFHFYSEPPRWPRA

GDF10

131

P55107
LYWPMSPFLSLHHPR

FOXG1

306

P55316
HGPSPSQWPAEYLQR

NEK5

396

Q6P3R8
NPNHPTLWRPEYGSY

GCLC

86

P48506
FPYPSFHWDPIRDPL

AUTS2

1061

Q8WXX7
TIWAPFERAAPLPAF

MEX3D

471

Q86XN8
CPPEVTPHYIWIDFL

PI4KAP1

31

Q8N8J0
GQHLPIFPAWVYERP

TUBGCP2

171

Q9BSJ2
HQERPYFQSWLLSPA

HAND1

36

O96004
RNQWALVAPVPHSFY

KBTBD7

461

Q8WVZ9
LREHPALLVEFYAPW

PDIA2

56

Q13087
RAEPYHWPLLVFLLP

PAQR6

76

Q6TCH4
YLPPLFWRFAAAPHI

PANX1

121

Q96RD7
PVWIPTRHLKFYNEP

ERVK-7

846

P63135
PVWIPTRHLKFYNEP

ERVK-6

846

Q9BXR3
PARPPPWVLYHNFTI

DQX1

636

Q8TE96
WPREPQVPLYVPKFH

EPS8L2

406

Q9H6S3
TPPLHRFPSWESRIY

PLEKHH2

541

Q8IVE3
PVLEHWDPRIAKNYP

MANEA

126

Q5SRI9
QSLRLYPFTDGWHPF

PKD1L2

2171

Q7Z442
TRFSHPPRYWPVLDN

PLD4

346

Q96BZ4
RPRAFFPLQTHGPWI

PRSS36

536

Q5K4E3
PYAHRFPPQTWLSAL

PPCS

91

Q9HAB8
LPVWDPRVNPSDRYH

PAPOLG

296

Q9BWT3
RPPAVSHTQPWYRAA

LINC00482

16

Q8N8I6
EFLLPRHPPIFHEWF

ATR

2426

Q13535
FWLIPPTAHNLELYE

KDM2A

231

Q9Y2K7
PFAWQHTYIPVLPPA

DENND2A

791

Q9ULE3
DRFPLWYRQASEHPA

CACNA2D4

796

Q7Z3S7
WYNLPRAPASPFREA

C19orf71

76

A6NCJ1
TAWHDPIVPAQYQAP

C19orf71

116

A6NCJ1
FSRHSDYPLSLQWLP

FUT11

171

Q495W5
PFPDHRPDQISRWYG

CFAP107

56

Q8N1D5
LPHCFYQSLPPRLGW

HEATR4

11

Q86WZ0
QAGRLWSRPPLNYFH

FOXR1

166

Q6PIV2
WSRPPLNYFHLIALA

FOXR1

171

Q6PIV2
PPNAQYWSQFHSVRP

DNAJC4

126

Q9NNZ3
NIHHIEWAPPQPEYF

AGBL2

191

Q5U5Z8
NPPAHYPGLSYRWLL

CNTN2

156

Q02246
PNPERFLIPPWVAYH

CYP11A1

116

P05108
YPFTWQHTYIPVLPA

DENND2C

716

Q68D51
QDFYHWRVFLPGLPS

ALOX12B

141

O75342
WRVFLPGLPSYVHIP

ALOX12B

146

O75342
FTRYLWPAPRGHLDP

MAN2B2

386

Q9Y2E5
FTPTLPPGRFWHQYD

ITIH6

931

Q6UXX5
CPPLYVLWRVHSQIP

DENND4B

1361

O75064
SPVWSEPLYSLRPEH

FNTB

16

P49356
PVQIHWYNTSNPLPY

DDHD1

681

Q8NEL9
GPLHPYWPQHLRLDN

EBP

6

Q15125
IARFSPYEWYNPHPC

GRIK2

581

Q13002
RLSPYEWYNPHPCLR

GRIK5

566

Q16478
WFPLIYDDPVNHPFI

SLC17A4

246

Q9Y2C5
LRFWYNLEIHSTPGP

CFAP47

2536

Q6ZTR5
HTEYIWYDPQLTPQP

DSEL

386

Q8IZU8
IRQFNCSPHPYWLPN

PPP3CA

331

Q08209
YTPDSRRPPNAWHKH

PTPRF

451

P10586
LPPTDYAHLQRSFWA

OSBPL7

291

Q9BZF2
WPAFERNRLYHSLGP

RALGPS2

411

Q86X27
SYRLVNWPEHLPEPA

MMP28

136

Q9H239
GSPYPWPLNHILAYQ

MTX2

146

O75431
PPDSPNAHWLTYSLL

USH2A

1076

O75445
PPVRRSEKPNWDYHA

MRPL44

56

Q9H9J2
DPDLREVWLNYPLHP

DROSHA

1071

Q9NRR4
PERHKPSFWYFVNPA

RHEX

146

Q6ZWK4
YALPPPLHQTEAWLQ

SYNE2

386

Q8WXH0
PLPWLLYTVIHRFQP

SLC24A2

581

Q9UI40
RHRWPTENYGPDSVP

RGPD2

831

P0DJD1
RAVWLRFHPSAYPPC

RHBDL3

321

P58872
SRPRAHTFPQQRYWP

SLC26A8

916

Q96RN1
FYPRRTPLQHELPAW

NT5DC3

516

Q86UY8
WHYRSCLLPQLHPQP

RABGGTA

181

Q92696
PPPATQAPRTWLHYY

PTCH2

771

Q9Y6C5
PFEKVTYRWTVPPHA

HEPH

511

Q9BQS7
YWPVHNELAFQPPIS

SMAD4

301

Q13485
HELQAPASRWRPYFA

SETD6

131

Q8TBK2
RPYFALWPELGRLEH

SETD6

141

Q8TBK2
HLLREWYLQDPYPNP

SIX6

141

O95475
AFPPVLEPRWFAHYD

SIPA1

106

Q96FS4
EWYAHNPYPSPREKR

SIX1

141

Q15475
RPWHAARHPYLPINS

MTA1

491

Q13330
RIGPYSWTPFPHVDF

NTAN1

226

Q96AB6
APQPWYADQRFTLPL

SLC38A8

141

A6NNN8
CPPEVTPHYIWIDFL

PI4KAP2

31

A4QPH2
FWNYARPPTVILEPH

SPAG4

291

Q9NPE6
PAASWAVQPHYQLPT

PM20D2

71

Q8IYS1
YQALGWQPPHFAHLP

EARS2

261

Q5JPH6
FEWLIAPMPPDHFYR

RIOX1

206

Q9H6W3
QRLSWPDLLYHPFIA

STK36

241

Q9NRP7
KHREEFPGWVYQPRP

SOX30

396

O94993
LPFTHWNIDPYLSRR

SGPP2

106

Q8IWX5
LQAPGEAHYWLPALF

SNF8

226

Q96H20
SRSAWLPYPNPNPHF

SEMA5A

341

Q13591
PRQTPIFDPTVHWLF

ALK

671

Q9UM73
PPAVFTRISHYRPWI

CMA1

226

P23946
GENWEPRVLPYHPAQ

CHPF

81

Q8IZ52
NPRFEPWYRHEIAPG

CHST10

206

O43529
PPHVRFPARQAWYRP

CHST14

316

Q8NCH0
FPNLVDPWTPHLYAR

NCAPD2

1086

Q15021
DPWTPHLYARLRDPA

NCAPD2

1091

Q15021
QRPHGARWAPNYDPL

CHRD

711

Q9H2X0
RALHLFPAPPAHWFY

CYP4Z1

41

Q86W10
HHGFEDWSQIRYPPP

TNIP1

561

Q15025
PNSRLFHLPEYTWRL

TNIP1

586

Q15025
NIRQFNCSPHPYWLP

PPP3CC

326

P48454
PFSLRKRWESEPHPY

RNF213

2291

Q63HN8
YAVCHRRLAPAWPPY

WFDC6

76

Q9BQY6
PVTYSHFAQDLWPQP

ZNF738

106

Q8NE65
HWSIYSRNFPLAVVP

nan

61

Q6ZQY7
PWNHLPDPEIFRQRF

ZNF24

41

P17028
WTPLPAREYQRFPHL

TAS1R1

701

Q7RTX1
PYVPNTAWQLRFSHL

MIPEP

611

Q99797
HIPGYNLPWEDPSFQ

PFAS

356

O15067
PVWLPTRHLKFYNEP

ERVK-10

846

P10266
PVWIPTRHLKFYNEP

ERVK-8

846

P63133
FLSLVHRTYPQDPAW

WDFY4

1801

Q6ZS81
HRTYPQDPAWRAPEF

WDFY4

1806

Q6ZS81
PVWIPTRHLKFYNEP

ERVK-11

846

Q9UQG0
PHIPQYISSVPWYID

SLU7

61

O95391
FCDHPARYVPRSPPW

PPP1R3F

191

Q6ZSY5
WPFLPLIRLYHRASD

RPAP1

1101

Q9BWH6
SVLEWPTNPQAHPYF

TLR7

1011

Q9NYK1
EWYAHNPYPSPREKR

SIX2

141

Q9NPC8
YPYHRDEPPRAPWNH

YLPM1

1181

P49750
PPVTYSHFAQDLWPE

ZNF430

106

Q9H8G1
PLGTHPRLFEWILNY

ZUP1

451

Q96AP4
AYRCLQWPAFFHQPP

TM6SF2

351

Q9BZW4
YFWATPRQVPSLQHL

WSB1

376

Q9Y6I7
SWSFQFPHPFLPNID

UGT2B28

261

Q9BY64
QLIVIPYPHNVPRSW

ITFG1

541

Q8TB96
PISYHLFPDPVVQWL

TMEM177

31

Q53S58
PLVPASWPYGLHQNF

TUT4

1591

Q5TAX3
YAPPRPGTLARWFVN

PLD2

326

O14939
HYSPAPWPLRPTNSE

SOCS6

131

O14544
VPRKAILYPHEAPSW

TRPM7

1016

Q96QT4
DPNYHPVLPWVVDFT

WDR81

376

Q562E7
RPYHISPVESQLPQW

ZMAT1

366

Q5H9K5
NKAVIRYLPWLYHPP

UNC79

2381

Q9P2D8
EHPYPDLPSRFLHWR

TRIM16L

186

Q309B1
LQIPFYRPHVDPWVI

VPS13D

66

Q5THJ4
AYHPESQRWTPLPSL

KLHL35

321

Q6PF15
FTEWASLFRHYSPPP

JMJD8

141

Q96S16