Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF711 GFI1B ZNF93 ZNF134 ZBTB46 ZNF594 ZNF492 ZNF836 CTCFL ZNF23 ZBTB6 ZNF100 ZNF560 ZNF665 ZNF175 ZNF92 ZNF197 ZFP1 ZNF254 ZNF805 ZNF69 ZNF888 ZNF525 PLAG1 PLAGL1 PLAGL2 ZNF420 ZNF721 ZBTB26 ZNF221 ZNF101 ZNF841 ZNF543 ZNF700 ZNF439 ZNF160 PRDM15 ZNF709 ZNF791 ZNF891 ZNF730 ZNF879 ZNF441 ZFX ZFY ZNF404 ZIC2 ZNF121 HDGF ZNF585B ZNF563

1.51e-4114127451GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF711 GFI1B ZNF93 ZNF134 ZNF594 ZNF492 ZNF836 CTCFL ZNF23 ZBTB6 ZNF100 ZNF560 ZNF665 ZNF175 ZNF92 ZNF197 ZFP1 ZNF254 ZNF805 ZNF69 ZNF888 ZNF525 PLAG1 PLAGL1 ZNF420 ZNF721 ZBTB26 ZNF221 ZNF101 ZNF841 ZNF543 ZNF700 ZNF439 ZNF160 PRDM15 ZNF709 ZNF791 ZNF891 ZNF730 ZNF879 ZNF441 ZFX ZFY ZNF404 ZIC2 ZNF121 HDGF ZNF585B ZNF563

5.73e-3814597449GO:0000977
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF711 GFI1B ZNF93 ZNF134 ZNF594 ZNF492 ZNF836 CTCFL ZNF23 ZBTB6 ZNF100 MTOR ZNF665 ZNF175 ZNF92 ZNF197 ZFP1 ZNF254 ZNF805 ZNF888 ZNF525 PLAG1 PLAGL1 ZNF420 ZNF721 ZBTB26 ZNF221 ZNF101 ZNF841 ZNF543 ZNF160 PRDM15 ZNF709 ZNF730 ZNF879 ZFX ZFY ZIC2 ZNF121 HDGF ZNF585B

7.19e-3012717441GO:0000987
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF711 GFI1B ZNF93 ZNF134 ZNF594 ZNF492 ZNF836 CTCFL ZNF23 ZBTB6 ZNF100 ZNF665 ZNF175 ZNF92 ZNF197 ZFP1 ZNF254 ZNF805 ZNF888 ZNF525 PLAG1 PLAGL1 ZNF420 ZNF721 ZBTB26 ZNF221 ZNF101 ZNF841 ZNF543 ZNF160 PRDM15 ZNF709 ZNF730 ZNF879 ZFX ZFY ZIC2 ZNF121 HDGF ZNF585B

5.78e-2912447440GO:0000978
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

GFI1B ZNF594 ZNF836 CTCFL ZNF175 ZNF197 PLAG1 PLAGL1 PLAGL2 ZNF721 ZNF101 ZNF841 PRDM15 ZNF709 ZFX ZFY ZIC2 ZNF585B

1.49e-125607418GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

GFI1B ZNF594 ZNF836 CTCFL ZNF175 ZNF197 PLAG1 PLAGL1 PLAGL2 ZNF721 ZNF101 ZNF841 PRDM15 ZNF709 ZFX ZFY ZIC2 ZNF585B

1.78e-125667418GO:0001216
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

ZNF93 ZNF134 ZBTB46 ZBTB6 ZNF175 PLAGL1 ZNF721 ZBTB26 ZNF101 ZNF709 HDGF

2.57e-083207411GO:0001227
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

ZNF93 ZNF134 ZBTB46 ZBTB6 ZNF175 PLAGL1 ZNF721 ZBTB26 ZNF101 ZNF709 HDGF

3.10e-083267411GO:0001217
GeneOntologyMolecularFunctionchromatin insulator sequence binding

CTCFL ZFX ZFY

1.69e-067743GO:0043035
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

ZNF711 GFI1B ZNF594 ZNF836 CTCFL ZNF175 ZNF197 RIPK2 ZNF407 PLAG1 PLAGL1 PLAGL2 ZNF721 POGZ ZNF841 PRDM15 ZFX ZFY ZIC2 HDGF ZNF585B

1.04e-0813907421GO:0045944
DomainZINC_FINGER_C2H2_2

ZNF711 CBLL1 GFI1B ZNF93 ZNF134 ZBTB46 ZNF594 ZNF492 ZNF836 CTCFL ZNF23 ZBTB6 ZNF100 ZNF234 ZNF560 ZNF665 ZNF175 ZNF92 ZNF197 ZFP1 ZNF254 ZNF805 ZNF69 ZNF525 ZNF407 PLAG1 PLAGL1 PLAGL2 ZNF420 ZNF721 ZBTB26 POGZ ZNF221 ZNF101 ZNF841 ZNF543 ZNF700 ZNF439 ZNF160 PRDM15 ZNF709 ZNF791 ZNF891 ZNF730 ZNF879 ZNF441 ZFX ZFY ZNF404 ZNF222 ZIC2 ZNF121 ZNF585B ZNF563

2.92e-597757354PS50157
DomainZINC_FINGER_C2H2_1

ZNF711 CBLL1 GFI1B ZNF93 ZNF134 ZBTB46 ZNF594 ZNF492 ZNF836 CTCFL ZNF23 ZBTB6 ZNF100 ZNF234 ZNF560 ZNF665 ZNF175 ZNF92 ZNF197 ZFP1 ZNF254 ZNF805 ZNF69 ZNF525 ZNF407 PLAG1 PLAGL1 PLAGL2 ZNF420 ZNF721 ZBTB26 POGZ ZNF221 ZNF101 ZNF841 ZNF543 ZNF700 ZNF439 ZNF160 PRDM15 ZNF709 ZNF791 ZNF891 ZNF730 ZNF879 ZNF441 ZFX ZFY ZNF404 ZNF222 ZIC2 ZNF121 ZNF585B ZNF563

3.37e-597777354PS00028
Domain-

ZNF711 CBLL1 GFI1B ZNF93 ZNF134 ZBTB46 ZNF594 ZNF492 ZNF836 CTCFL ZNF23 ZBTB6 ZNF100 ZNF234 ZNF560 ZNF665 ZNF175 ZNF92 ZNF197 ZFP1 ZNF254 ZNF805 ZNF69 ZNF407 PLAG1 PLAGL1 PLAGL2 ZNF420 ZNF721 ZBTB26 ZNF221 ZNF101 ZNF841 ZNF543 ZNF700 ZNF439 ZNF160 PRDM15 ZNF709 ZNF791 ZNF891 ZNF730 ZNF879 ZNF441 ZFX ZFY ZNF404 ZNF222 ZIC2 ZNF121 ZNF585B ZNF563

1.09e-5867973523.30.160.60
DomainZnf_C2H2

ZNF711 GFI1B ZNF93 ZNF134 ZBTB46 ZNF594 ZNF492 ZNF836 CTCFL ZNF23 ZBTB6 ZNF100 ZNF234 ZNF560 ZNF665 ZNF175 ZNF92 ZNF197 ZFP1 ZNF254 ZNF805 ZNF69 ZNF525 ZNF407 PLAG1 PLAGL1 PLAGL2 ZNF420 ZNF721 ZBTB26 POGZ ZNF221 ZNF101 ZNF841 ZNF543 ZNF700 ZNF439 ZNF160 PRDM15 ZNF709 ZNF791 ZNF891 ZNF730 ZNF879 TRIM23 ZNF441 ZFX ZFY ZNF404 ZNF222 ZIC2 ZNF121 ZNF585B ZNF563

2.37e-588057354IPR007087
DomainZnF_C2H2

ZNF711 CBLL1 GFI1B ZNF93 ZNF134 ZBTB46 ZNF594 ZNF492 ZNF836 CTCFL ZNF23 ZBTB6 ZNF100 ZNF234 ZNF560 ZNF665 ZNF175 ZNF92 ZNF197 ZFP1 ZNF254 ZNF805 ZNF69 ZNF525 ZNF407 PLAG1 PLAGL1 PLAGL2 ZNF420 ZNF721 ZBTB26 POGZ ZNF221 ZNF101 ZNF841 ZNF543 ZNF700 ZNF439 ZNF160 PRDM15 ZNF709 ZNF791 ZNF891 ZNF730 ZNF879 ZNF441 ZFX ZFY ZNF404 ZNF222 ZIC2 ZNF121 ZNF585B ZNF563

2.91e-588087354SM00355
Domainzf-C2H2

ZNF711 GFI1B ZNF93 ZNF134 ZBTB46 ZNF594 ZNF492 ZNF836 CTCFL ZNF23 ZBTB6 ZNF100 ZNF234 ZNF560 ZNF665 ZNF175 ZNF92 ZNF197 ZFP1 ZNF254 ZNF805 ZNF69 ZNF525 ZNF407 PLAGL1 PLAGL2 ZNF420 ZNF721 ZBTB26 POGZ ZNF221 ZNF101 ZNF841 ZNF543 ZNF700 ZNF439 ZNF160 PRDM15 ZNF709 ZNF791 ZNF891 ZNF730 ZNF879 ZNF441 ZFX ZFY ZNF404 ZNF222 ZIC2 ZNF121 ZNF585B ZNF563

3.24e-586937352PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF711 CBLL1 GFI1B ZNF93 ZNF134 ZBTB46 ZNF594 ZNF492 ZNF836 CTCFL ZNF23 ZBTB6 ZNF100 ZNF234 ZNF560 ZNF665 ZNF175 ZNF92 ZNF197 ZFP1 ZNF254 ZNF805 ZNF69 ZNF407 PLAG1 PLAGL1 PLAGL2 ZNF420 ZNF721 ZBTB26 ZNF221 ZNF101 ZNF841 ZNF543 ZNF700 ZNF439 ZNF160 PRDM15 ZNF709 ZNF791 ZNF891 ZNF730 ZNF879 ZNF441 ZFX ZFY ZNF404 ZNF222 ZIC2 ZNF121 ZNF585B ZNF563

3.50e-586947352IPR013087
DomainZnf_C2H2-like

ZNF711 CBLL1 GFI1B ZNF93 ZNF134 ZBTB46 ZNF594 ZNF492 ZNF836 CTCFL ZNF23 ZBTB6 ZNF100 ZNF234 ZNF560 ZNF665 ZNF175 ZNF92 ZNF197 ZFP1 ZNF254 ZNF805 ZNF69 ZNF407 PLAG1 PLAGL1 PLAGL2 ZNF420 ZNF721 ZBTB26 POGZ ZNF221 ZNF101 ZNF841 ZNF543 ZNF700 ZNF439 ZNF160 PRDM15 ZNF709 ZNF791 ZNF891 ZNF730 ZNF879 ZNF441 ZFX ZFY ZNF404 ZNF222 ZIC2 ZNF121 ZNF585B ZNF563

8.29e-577967353IPR015880
DomainKRAB

ZNF93 ZNF492 ZNF836 ZNF23 ZNF100 ZNF234 ZNF560 ZNF175 ZNF92 ZNF197 ZFP1 ZNF254 ZNF805 ZNF69 ZNF420 ZNF221 ZNF101 ZNF543 ZNF700 ZNF439 ZNF160 ZNF709 ZNF791 ZNF891 ZNF730 ZNF879 ZNF441 ZNF404 ZNF222 ZNF585B ZNF563

2.92e-343587331PS50805
DomainKRAB

ZNF93 ZNF492 ZNF836 ZNF23 ZNF100 ZNF234 ZNF560 ZNF175 ZNF92 ZNF197 ZFP1 ZNF254 ZNF805 ZNF69 ZNF420 ZNF221 ZNF101 ZNF543 ZNF700 ZNF439 ZNF160 ZNF709 ZNF791 ZNF891 ZNF730 ZNF879 ZNF441 ZNF404 ZNF222 ZNF585B ZNF563

7.57e-343697331SM00349
DomainKRAB

ZNF93 ZNF492 ZNF836 ZNF23 ZNF100 ZNF234 ZNF560 ZNF175 ZNF92 ZNF197 ZFP1 ZNF254 ZNF805 ZNF69 ZNF420 ZNF221 ZNF101 ZNF543 ZNF700 ZNF439 ZNF160 ZNF709 ZNF791 ZNF891 ZNF730 ZNF879 ZNF441 ZNF404 ZNF222 ZNF585B ZNF563

8.25e-343707331IPR001909
DomainKRAB

ZNF93 ZNF492 ZNF836 ZNF100 ZNF234 ZNF560 ZNF175 ZNF92 ZNF197 ZFP1 ZNF254 ZNF805 ZNF69 ZNF420 ZNF221 ZNF101 ZNF543 ZNF700 ZNF439 ZNF160 ZNF709 ZNF791 ZNF891 ZNF730 ZNF879 ZNF441 ZNF404 ZNF222 ZNF585B ZNF563

1.17e-323587330PF01352
Domainzf-C2H2_6

GFI1B ZNF93 ZNF492 ZNF836 ZNF100 ZNF234 ZNF560 ZNF92 ZNF197 ZNF805 ZNF69 PLAGL2 ZNF420 ZNF721 ZNF841 ZNF543 ZNF700 ZNF439 ZNF160 ZNF709 ZNF791 ZNF891 ZNF730 ZNF879 ZNF404 ZNF121

5.46e-283147326PF13912
DomainTranscrp_activ_Zfx/Zfy-dom

ZNF711 ZFX ZFY

5.73e-083733IPR006794
DomainZfx_Zfy_act

ZNF711 ZFX ZFY

5.73e-083733PF04704
Domainzf-H2C2_2

ZFP1 ZNF891

1.33e-0314732PF13465
DomainC2H2_Znf_fam

PLAG1 PLAGL2

3.93e-0324732IPR027775
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

ZNF711 ZNF492 ZNF23 ZNF100 ZNF234 ZNF560 MTOR ZNF665 ZNF175 ZNF92 ZNF197 ZFP1 ZNF254 PLAGL1 ZNF420 ZNF721 ZNF221 ZNF101 ZNF543 ZNF700 ZNF439 ZNF160 ZNF709 ZNF791 ZNF730 ZNF441 ZNF222 ZNF585B ZNF563

4.12e-1713875029M734
PathwayREACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS

ZNF93 ZNF836 ZNF665 ZNF254 ZNF101 ZNF160 ZNF709

9.27e-1056507MM17236
PathwayREACTOME_GENERIC_TRANSCRIPTION_PATHWAY

ZNF711 ZNF93 ZNF836 ZNF23 MTOR ZNF665 ZFP1 ZNF254 ZNF420 ZNF721 ZNF221 ZNF101 ZNF160 ZNF709 ZNF585B ZNF563

4.44e-097685016MM14851
PathwayREACTOME_GENE_EXPRESSION_TRANSCRIPTION

ZNF711 ZNF93 ZNF836 ZNF23 MTOR ZNF665 ZFP1 ZNF254 ZNF420 ZNF721 ZNF221 ZNF101 ZNF160 ZNF709 ZNF585B ZNF563

2.43e-0710225016MM15436
PathwayREACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION

ZNF93 ZNF836 ZNF665 ZNF254 ZNF101 ZNF160 ZNF709

4.71e-07136507MM14848
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF93 ZNF100 ZNF92 ZNF197 ZFP1 ZNF805 ZNF721 ZNF101 ZNF841 ZNF543 ZNF160 ZNF791 ZNF441 ZNF121 ZNF563

4.30e-20181741537372979
Pubmed

Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.

ZNF836 ZNF665 ZNF175 ZNF420 ZNF721 ZNF101 ZNF160 ZNF585B

1.20e-13497489630514
Pubmed

A census of human transcription factors: function, expression and evolution.

ZNF711 GFI1B CTCFL ZNF23 ZNF175 ZNF197 ZNF254 PLAG1 PLAGL1 PLAGL2 ZNF160 ZFX ZFY ZIC2

6.60e-09908741419274049
Pubmed

Transcriptional activation capacity of the novel PLAG family of zinc finger proteins.

PLAG1 PLAGL1 PLAGL2

9.25e-0937439722527
Pubmed

Characterization of the ZFX family of transcription factors that bind downstream of the start site of CpG island promoters.

ZNF711 ZFX ZFY

9.25e-09374332406922
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

GFI1B ZNF93 ZBTB46 ZNF836 ZNF665 ZNF175 ZNF254 PLAG1 PLAGL2 ZNF721 POGZ ZNF160 ZYX

1.48e-08808741320412781
Pubmed

Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.

ZNF93 ZNF100 ZNF92 ZNF101

3.37e-08167448467795
Pubmed

Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.

ZNF234 ZNF221 ZNF404 ZNF222

8.91e-082074412743021
Pubmed

Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937.

ZNF594 ZNF23 ZNF234 ZNF160

1.10e-07217447865130
Pubmed

Repression of the Transactivating Capacity of the Oncoprotein PLAG1 by SUMOylation.

PLAG1 PLAGL1 PLAGL2

1.84e-07674315208321
Pubmed

Comparative analysis of KRAB zinc finger proteins in rodents and man: evidence for several evolutionarily distinct subfamilies of KRAB zinc finger genes.

ZNF93 ZNF254 ZNF101

7.70e-07974310360839
Pubmed

Members of the Plag gene family are expressed in complementary and overlapping regions in the developing murine nervous system.

PLAG1 PLAGL1 PLAGL2

1.10e-061074316193498
Pubmed

Zinc finger protein genes in the mouse genome.

ZFP1 ZFX ZFY

2.01e-06127431797234
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

ZNF23 ZBTB6 PLAG1 PLAGL2 POGZ ZNF101 ZYX ZFX ZFY ZNF585B

2.58e-06709741022988430
Pubmed

Plag1 and Plagl2 have overlapping and distinct functions in telencephalic development.

PLAG1 PLAGL1 PLAGL2

2.60e-061374330361413
Pubmed

Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.

ZNF93 ZNF254 ZNF721

4.13e-061574315885501
Pubmed

Zfa is an expressed retroposon derived from an alternative transcript of the Zfx gene.

ZFX ZFY

4.47e-0627421691708
Pubmed

The structure of the Zfx gene on the mouse X chromosome.

ZFX ZFY

4.47e-0627428188262
Pubmed

Mapping the human ZFX locus to Xp21.3 by in situ hybridization.

ZFX ZFY

4.47e-0627422497060
Pubmed

Comparison of ZFY and ZFX gene structure and analysis of alternative 3' untranslated regions of ZFY.

ZFX ZFY

4.47e-0627422041734
Pubmed

Gene expression, X-inactivation, and methylation during spermatogenesis: the case of Zfa, Zfx, and Zfy in mice.

ZFX ZFY

4.47e-0627428318216
Pubmed

Mouse Zfx protein is similar to Zfy-2: each contains an acidic activating domain and 13 zinc fingers.

ZFX ZFY

4.47e-0627422105457
Pubmed

[Expression of Zfx in mouse testicular spermatogenic cells].

ZFX ZFY

4.47e-06274238602753
Pubmed

Differential rates of evolution for the ZFY-related zinc finger genes, Zfy, Zfx, and Zfa in the mouse genus Mus.

ZFX ZFY

4.47e-06274212716983
Pubmed

Intron/exon structure confirms that mouse Zfy1 and Zfy2 are members of the ZFY gene family.

ZFX ZFY

4.47e-0627429126493
Pubmed

EPHA3 enhances macrophage autophagy and apoptosis by disrupting the mTOR signaling pathway in mice with endometriosis.

MTOR EPHA3

4.47e-06274231262977
Pubmed

Transcription factor Zfx controls BCR-induced proliferation and survival of B lymphocytes.

ZFX ZFY

4.47e-06274219329779
Pubmed

Chromosomal localization of ZFX--a human gene that escapes X inactivation--and its murine homologs.

ZFX ZFY

4.47e-0627421970799
Pubmed

Evolution of the Zfx and Zfy genes: rates and interdependence between the genes.

ZFX ZFY

4.47e-0627428487630
Pubmed

Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification.

PLAGL1 PLAGL2

4.47e-06274236437415
Pubmed

Comparison of human ZFY and ZFX transcripts.

ZFX ZFY

4.47e-0627422308929
Pubmed

RNAi as a tool to control the sex ratio of mouse offspring by interrupting Zfx/Zfy genes in the testis.

ZFX ZFY

4.47e-06274228251288
Pubmed

Circ_0000520 contributes to triple-negative breast cancer progression through mediating the miR-1296/ZFX axis.

ZFX ZFY

4.47e-06274234324278
Pubmed

Zfx mutation results in small animal size and reduced germ cell number in male and female mice.

ZFX ZFY

4.47e-0627429187153
Pubmed

Regional assignments of the zinc finger Y-linked gene (ZFY) and related sequences on human and mouse chromosomes.

ZFX ZFY

4.47e-0627422265557
Pubmed

Zfy gene expression patterns are not compatible with a primary role in mouse sex determination.

ZFX ZFY

1.34e-0537422480529
Pubmed

Genetic dissection of mammalian fertility pathways.

ZFX ZFY

1.34e-05374212479614
Pubmed

X chromosome genes and premature ovarian failure.

ZFX ZFY

1.34e-05374211299520
Pubmed

Isolation of monochromosomal hybrids for mouse chromosomes 3, 6, 10, 12, 14, and 18.

ZFX ZFY

1.34e-0537429060403
Pubmed

Blockade of ZFX Alleviates Hypoxia-Induced Pulmonary Vascular Remodeling by Regulating the YAP Signaling.

ZFX ZFY

1.34e-05374238310188
Pubmed

ADAMTS9 is a functional tumor suppressor through inhibiting AKT/mTOR pathway and associated with poor survival in gastric cancer.

ADAMTS9 MTOR

1.34e-05374222907434
Pubmed

YAC clone contigs surrounding the Zfx and Pola loci on the mouse X chromosome.

ZFX ZFY

1.34e-0537428406471
Pubmed

Identification of differentially expressed genes in mouse spermatogenesis.

ZNF836 ZNF665 ZNF160

2.61e-052774314581517
Pubmed

ZFX controls propagation and prevents differentiation of acute T-lymphoblastic and myeloid leukemia.

ZFX ZFY

2.67e-05474224485662
Pubmed

FOXM1-regulated ZIC2 promotes the malignant phenotype of renal clear cell carcinoma by activating UBE2C/mTOR signaling pathway.

MTOR ZIC2

2.67e-05474237496990
Pubmed

Plag1 and Plagl2 are oncogenes that induce acute myeloid leukemia in cooperation with Cbfb-MYH11.

PLAG1 PLAGL2

2.67e-05474215585652
Pubmed

Zfx controls the self-renewal of embryonic and hematopoietic stem cells.

ZFX ZFY

2.67e-05474217448993
Pubmed

Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.

ZNF93 ZNF254 ZNF721

3.25e-052974314563677
Pubmed

The human gene ZFP161 on 18p11.21-pter encodes a putative c-myc repressor and is homologous to murine Zfp161 (Chr 17) and Zfp161-rs1 (X Chr).

ZFX ZFY

4.45e-0557429244432
Pubmed

Chromosome mapping and expression of a putative testis-determining gene in mouse.

ZFX ZFY

4.45e-0557422563174
Pubmed

MSG1 (melanocyte-specific gene 1): mapping to chromosome Xq13.1, genomic organization, and promoter analysis.

ZFX ZFY

4.45e-0557429721210
Pubmed

The KRAB zinc finger protein RSL1 modulates sex-biased gene expression in liver and adipose tissue to maintain metabolic homeostasis.

ZNF93 ZNF254

4.45e-05574224190968
Pubmed

Zfx facilitates tumorigenesis caused by activation of the Hedgehog pathway.

ZFX ZFY

4.45e-05574225164012
Pubmed

A pair of mouse KRAB zinc finger proteins modulates multiple indicators of female reproduction.

ZNF93 ZNF254

4.45e-05574220042539
Pubmed

Maintenance of X inactivation of the Rps4, Zfx, and Ube1 genes in a mouse in vitro system.

ZFX ZFY

4.45e-0557427681608
Pubmed

Sequence and expression of murine cDNAs encoding Xlr3a and Xlr3b, defining a new X-linked lymphocyte-regulated Xlr gene subfamily.

ZFX ZFY

6.66e-0567427821804
Pubmed

The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons.

ZNF93 ZNF254

6.66e-05674230846446
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ZNF836 NAA25 ZNF234 ADAMTS9 ZNF92 EFEMP2 ZNF197 POGZ ZNF841 ZNF439 ZNF879

8.30e-051285741135914814
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZNF836 ARHGEF28 ADAMTS9 ZNF665 ZNF407 ZBTB26 ZNF160

8.74e-0549374715368895
Pubmed

The KRAB zinc finger protein RSL1 regulates sex- and tissue-specific promoter methylation and dynamic hormone-responsive chromatin configuration.

ZNF93 ZNF254

9.31e-05774222801370
Pubmed

An evaluation of the inactive mouse X chromosome in somatic cell hybrids.

ZFX ZFY

9.31e-0577428460399
Pubmed

Genetic mapping in the mouse of Kif4, a gene encoding a kinesin-like motor protein.

ZFX ZFY

9.31e-0577429196009
Pubmed

Characterization of cDNAs encoding the murine interleukin 2 receptor (IL-2R) gamma chain: chromosomal mapping and tissue specificity of IL-2R gamma chain expression.

ZFX ZFY

9.31e-0577428378320
Pubmed

Embryonic growth and the evolution of the mammalian Y chromosome. II. Suppression of selfish Y-linked growth factors may explain escape from X-inactivation and rapid evolution of Sry.

ZFX ZFY

9.31e-0577427928394
Pubmed

The Dazh gene is expressed in male and female embryonic gonads before germ cell sex differentiation.

ZFX ZFY

9.31e-0577429588208
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

ZNF23 ZBTB6 ZNF175 ZNF92 ZNF407 PLAGL2 ZFY ZIC2 HDGF

1.01e-0487774920211142
Pubmed

Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome.

ZFX ZFY

1.24e-0487422034279
Pubmed

The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.

ZNF93 ZNF92

1.24e-0487422023909
Pubmed

Genetic mapping in the region of the mouse X-inactivation center.

ZFX ZFY

1.24e-0487421974879
Pubmed

High-density molecular map of the central span of the mouse X chromosome.

ZFX ZFY

1.24e-0487421675191
Pubmed

Praja1, a novel gene encoding a RING-H2 motif in mouse development.

ZFX ZFY

1.59e-0497429393880
Pubmed

exma: an X-linked insertional mutation that disrupts forebrain and eye development.

ZFX ZFY

1.59e-04974211956759
Pubmed

Structure, chromosomal location, and expression pattern of three mouse genes homologous to the human MAGE genes.

ZFX ZFY

1.59e-0497427590750
Pubmed

Cloning and characterization of a new human Xq13 gene, encoding a putative helicase.

ZFX ZFY

1.59e-0497427874112
Pubmed

The mouse genes encoding the third pair of beta-type proteasome subunits regulated reciprocally by IFN-gamma: structural comparison, chromosomal localization, and analysis of the promoter.

ZFX ZFY

1.59e-0497429300697
Pubmed

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

CBLL1 EFEMP2 RIPK2 ZBTB26 POGZ ZYX TRIM23 ZFY

1.80e-0474274826871637
Pubmed

Genetic and molecular evidence of an X-chromosome deletion spanning the tabby (Ta) and testicular feminization (Tfm) loci in the mouse.

ZFX ZFY

1.99e-04107422055107
Pubmed

Mapping of the phosphorylase kinase alpha subunit gene on the mouse X chromosome.

ZFX ZFY

1.99e-04107421973380
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

ZNF711 CBLL1 NAA25 PDLIM7 ZNF525 ZNF407 ZNF420 POGZ ZNF160 RPL10

2.27e-041203741029180619
Pubmed

Characterization of a murine gene expressed from the inactive X chromosome.

ZFX ZFY

2.43e-04117422034278
Pubmed

Zic2 controls cerebellar development in cooperation with Zic1.

EPHA3 ZIC2

2.43e-041174211756505
Pubmed

Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction.

ZNF836 ZNF665 ZNF160

2.90e-046074318023262
Pubmed

The construction of human somatic cell hybrids containing portions of the mouse X chromosome and their use to generate DNA probes via interspersed repetitive sequence polymerase chain reaction.

ZFX ZFY

2.91e-04127421916827
Pubmed

Protein interactions of the transcription factor Hoxa1.

PDLIM7 EFEMP2 TRIM23

3.20e-046274323088713
Pubmed

ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex.

ZBTB46 ZBTB6 ZBTB26

3.35e-046374334351428
Pubmed

Localization of murine X and autosomal sequences homologous to the human Y located testis-determining region.

ZFX ZFY

3.43e-04137422721933
Pubmed

Rps4 maps near the inactivation center on the mouse X chromosome.

ZFX ZFY

3.43e-04137421740345
Pubmed

XIST and the mapping of the X chromosome inactivation centre.

ZFX ZFY

3.43e-04137421772416
Pubmed

The murine interleukin-2 receptor gamma chain gene: organization, chromosomal localization and expression in the adult thymus.

ZFX ZFY

3.43e-04137427805729
Pubmed

The DNA sequence and biology of human chromosome 19.

ZNF93 ZNF175 ZNF888 ZNF221 ZNF222

3.56e-0428474515057824
Pubmed

Mapping of a liver phosphorylase kinase alpha-subunit gene on the mouse X chromosome.

ZFX ZFY

4.00e-04147428432533
Pubmed

Detailed comparative map of human chromosome 19q and related regions of the mouse genome.

ZNF836 ZNF665 ZNF160

4.02e-04677438812484
Pubmed

Identification and genetic mapping of differentially expressed genes in mice differing at the If1 interferon regulatory locus.

RPL10 ZFX ZFY

4.02e-046774310441734
Pubmed

Molecular phylogenetics and the origins of placental mammals.

ZFX ZFY

4.61e-041574211214319
Pubmed

Identification and characterization of members of the FKHR (FOX O) subclass of winged-helix transcription factors in the mouse.

ZFX ZFY

4.61e-041574211353388
Pubmed

Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis.

ARHGEF28 RIPK2

4.61e-041574223892723
Pubmed

Evolutionary strata on the mouse X chromosome correspond to strata on the human X chromosome.

ZFX ZFY

4.61e-041574214762062
Pubmed

Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation.

ZFX ZFY

5.95e-041774219571810
Pubmed

Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping.

ZNF420 POGZ ZFX

6.27e-047874328611094
Pubmed

Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.

ZFP1 POGZ ZNF585B

7.52e-048374320562864
InteractionTRIM28 interactions

CBLL1 ZNF93 ZNF492 ZNF100 MTOR ZNF92 ZNF197 ZFP1 ZNF254 ZNF805 ZNF888 ZNF420 ZNF721 ZNF101 ZNF841 ZNF543 ZNF160 ZNF791 TRIM23 ZNF441 RPL10 ZNF121 ZNF585B ZNF563

8.48e-1114747124int:TRIM28
InteractionLTBP2 interactions

ZNF594 ZNF92 ZNF254 ZNF101 ZNF709 ZNF791 RPL10

1.97e-0885717int:LTBP2
InteractionNOTCH2 interactions

ZNF594 ADAMTS9 ZNF92 ZNF888 ZNF407 ZNF709 ZNF791 ZYX RPL10 ZNF121

2.20e-064237110int:NOTCH2
InteractionZNF467 interactions

ZNF100 ZNF92 ZNF254 ZNF721 ZNF101 ZNF791 ZNF121

3.19e-06179717int:ZNF467
InteractionSUMO1P1 interactions

ZBTB6 ZBTB26 TRIM23 EPHA3

1.30e-0541714int:SUMO1P1
InteractionFBLN5 interactions

GFI1B ZNF492 ZNF92 ZNF407 RPL10 ZIC2

2.06e-05159716int:FBLN5
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF134 ZNF836 ZNF234 ZNF665 ZNF175 ZNF805 ZNF888 ZNF525 ZNF420 ZNF221 ZNF841 ZNF543 ZNF160 ZNF404 ZNF222 ZNF585B

6.33e-1111927416chr19q13
Cytoband19p13.2

ZNF560 ZNF69 ZNF700 ZNF439 ZNF709 ZNF791 ZNF441 ZNF563

3.85e-0922974819p13.2
Cytoband19p12

ZNF93 ZNF492 ZNF100 ZNF254 ZNF730

3.75e-079074519p12
CytobandEnsembl 112 genes in cytogenetic band chr19p13

ZNF560 ZNF69 ZNF101 ZNF700 ZNF439 ZNF709 ZNF791 ZNF441 ZNF121 ZNF563

6.21e-077977410chr19p13
CytobandEnsembl 112 genes in cytogenetic band chr19p12

ZNF93 ZNF492 ZNF100 ZNF254 ZNF730

1.70e-06122745chr19p12
Cytoband19q13.41

ZNF836 ZNF888 ZNF841

2.80e-047874319q13.41
Cytoband19q13.31

ZNF234 ZNF404

1.01e-032974219q13.31
Cytoband19q13.42

ZNF665 ZNF525 ZNF160

1.11e-0312574319q13.42
Cytoband9q33.2

ZBTB6 ZBTB26

1.83e-03397429q33.2
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF711 GFI1B ZNF93 ZNF134 ZBTB46 ZNF594 ZNF492 ZNF836 CTCFL ZNF23 ZBTB6 ZNF100 ZNF234 ZNF560 ZNF665 ZNF175 ZNF92 ZNF197 ZFP1 ZNF254 ZNF805 ZNF69 ZNF888 ZNF525 ZNF407 PLAG1 PLAGL1 PLAGL2 ZNF420 ZNF721 ZBTB26 ZNF221 ZNF101 ZNF841 ZNF543 ZNF700 ZNF439 ZNF160 PRDM15 ZNF709 ZNF791 ZNF891 ZNF730 ZNF879 ZNF441 ZFX ZFY ZNF404 ZNF222 ZIC2 ZNF121 ZNF585B ZNF563

1.34e-59718715328
CoexpressionGSE2706_R848_VS_LPS_2H_STIM_DC_UP

ZNF134 ZNF836 CTCFL ZNF23 PLAGL2 ZNF791 ZNF441

1.02e-06190737M4706
CoexpressionGSE2770_UNTREATED_VS_ACT_CD4_TCELL_48H_DN

ZNF420 ZNF439 ZNF709 ZNF791 ZNF222 ZNF563

1.82e-05196736M6073
CoexpressionGSE2706_UNSTIM_VS_2H_LPS_DC_UP

ZNF23 ZNF805 ZBTB26 ZNF439 ZNF791 ZNF879

1.87e-05197736M4695
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Serous_adenocarcinoma-5|TCGA-Endometrium / Sample_Type by Project: Shred V9

ZNF492 CTCFL PLAG1 PLAGL2 ZNF439 ZNF730

2.50e-0715774659450e9f580555091b159fbbe0a0756e51bcd9ad
Drugvinylene

ZNF93 ZNF492 ZNF175 ZNF197 PLAG1 PLAGL2 PRDM15 ZFX ZFY

8.91e-08245739CID000006326
DrugPimethixene maleate [13187-06-9]; Down 200; 9.8uM; MCF7; HT_HG-U133A

ZNF93 ZBTB6 CYP3A4 PDLIM7 ZNF721 ZMYM6 TRIM23

2.96e-061947377468_DN
Diseasestem Cell Growth Factor beta measurement

ZNF197 ZNF700 ZNF121 ZNF563

2.46e-0575664EFO_0008292
Diseasefactor VII activating protease measurement

MALRD1 ZNF197 ZNF121

2.58e-0455663EFO_0009368
DiseasePremature atrial contractions

ZFP1 ZNF69 ZNF700

2.58e-0455663HP_0006699
Diseasegout, hyperuricemia

MALRD1 ZNF730

5.79e-0416662EFO_0004274, EFO_0009104
DiseaseCarcinoma of lung

MXRA5 EPHA3

1.21e-0323662C0684249
DiseaseLarge cell carcinoma of lung

MTOR EPHA3

2.34e-0332662C0345958
DiseaseProstatic Neoplasms

CYP3A4 EFEMP2 ZNF160 RPL10 ZIC2 SPINK5

2.54e-03616666C0033578
DiseaseMalignant neoplasm of prostate

CYP3A4 EFEMP2 ZNF160 RPL10 ZIC2 SPINK5

2.54e-03616666C0376358
Diseasebilirubin measurement

ASIC2 ZNF407 ZNF101 HDGF ZNF563

3.11e-03442665EFO_0004570
Diseaseorofacial cleft

EPHA3 ZIC2

3.12e-0337662MONDO_0000358
DiseasePrecursor T-Cell Lymphoblastic Leukemia-Lymphoma

MTOR RPL10

6.31e-0353662C1961099

Protein segments in the cluster

PeptideGeneStartEntry
HTHEKPFKCSMCKYA

CTCFL

336

Q8NI51
DMMLYCKFKGQECGH

ASIC2

166

Q16515
KMKKIYGEFCCHHKE

ARHGEF28

946

Q8N1W1
HGNKCAMCKAVFQKE

SPINK5

661

Q9NQ38
YSPGMDAYHCVKCNK

GFI1B

156

Q5VTD9
GFCMFDMECHKKYGK

CYP3A4

56

P08684
KCGDLVFAKMKGYPH

HDGF

11

P51858
DYEKMFGTKCHGCDF

PDLIM7

391

Q9NR12
YDCAILHEKKGDKMC

CBLL1

131

Q75N03
GHCIEKMQKCDFKYD

MALRD1

1061

Q5VYJ5
HCKYGFCVPKEMDVP

ADAMTS9

571

Q9P2N4
GFYKALDGNMKCAKC

EPHA3

276

P29320
IPEACKGEMKCINHY

EFEMP2

61

O95967
HDKYCKDLMGFGTKP

MTOR

296

P42345
PNKMAFGCEECGKKY

PLAGL1

86

Q9UM63
CANKYMVKSCGKDGF

RPL10

71

P27635
EYLCAECGKGMKTKH

PRDM15

1111

P57071
YCCPEMVEYQKKGKS

POGZ

396

Q7Z3K3
KPHQCMYCDKMFHRK

PLAGL2

96

Q9UPG8
EKPYKCNECGKAFSM

ZNF665

371

Q9H7R5
KPYKCNDCGKTFSHM

ZNF525

381

Q8N782
HSPEKTHKCNYCEKM

PLAG1

86

Q6DJT9
AHMEKKPYECSECGK

ZFP1

261

Q6P2D0
FIHMGKKHYKCEECG

ZNF93

361

P35789
KMIHTGEKPYKCEEC

ZNF100

476

Q8IYN0
MGEKPYQCKECGKAF

ZNF700

301

Q9H0M5
HMGEKPYECKDCGKA

ZNF700

726

Q9H0M5
IHMEDKPYKCEECGK

ZNF92

306

Q03936
NHMEDKPYKCEECGK

ZNF92

446

Q03936
GKKFYKCDMCCKHFN

ZNF197

366

O14709
KPYKCNECGKAFSMH

ZNF160

451

Q9HCG1
EKPYKCNECGKAFSM

ZNF160

646

Q9HCG1
SMEKPYKCKECGEAF

ZNF441

666

Q8N8Z8
RMHTGEKPYKCKECG

ZNF791

516

Q3KP31
KAQDCYFMKLHHCPG

RIPK2

376

O43353
DKPYKCKECGKAFMH

ZNF721

206

Q8TF20
PENKYFHHMGKCCPD

XAF1

161

Q6GPH4
FHHMGKCCPDSEFKK

XAF1

166

Q6GPH4
MREKPYKCNECGKSF

ZNF585B

181

Q52M93
RMHTGEKPYKCKECG

ZNF709

216

Q8N972
GCKNVDEFKMHKKGY

ZNF730

116

Q6ZMV8
HCMVHTGEKPYKCED

ZNF234

306

Q14588
GMKPYECKQCGKAFR

ZNF404

211

Q494X3
NHTGEKPYKCMECGK

ZNF841

726

Q6ZN19
GEKPYMCNKCGKVFN

ZNF888

266

P0CJ79
KSMDECKVHKECYNG

ZNF492

86

Q9P255
MHTGEKPYECKQCSK

ZNF563

246

Q8TA94
KMHTVEKPYECKECG

ZNF121

136

P58317
YKGKMFLFCGKNCSD

ZMYM6

446

O95789
MGEKCYKCDVCGKEF

ZNF221

221

Q9UK13
GKMHTGEKRYECKYC

ZNF101

216

Q8IZC7
GEKPYKCMECGKAFN

ZNF543

251

Q08ER8
GEKPYKCMECGKAFN

ZNF543

391

Q08ER8
MHTGERPYKCKECGK

ZNF879

281

B4DU55
MRIHTGEKPYKCKEC

ZNF879

531

B4DU55
HTKDYPHKCDMCDKG

ZFX

656

P17010
VVMHSGDGPYKCKFC

ZNF69

211

Q9UC07
LDKNFHMKCYKCEDC

ZYX

526

Q15942
HMKCYKCEDCGKPLS

ZYX

531

Q15942
TNEKPYECKECGKMF

ZNF420

386

Q8TAQ5
KPYECKECGKLFMWH

ZNF594

706

Q96JF6
HSGEKPYQCKMCGKA

ZNF23

246

P17027
KHEGVKMYNCPKCDY

ZNF407

1766

Q9C0G0
MCCVCKEYGKHQGHK

TRIM23

201

P36406
KEPKMHKCKYCDYET

ZNF711

471

Q9Y462
SHMGEKQYECKECGK

ZNF891

341

A8MT65
EKPYKCMECGKAFNR

ZNF805

256

Q5CZA5
GEQMHYKCSECGKAF

ZNF134

171

P52741
KRMHTGEKPYKCEEC

ZNF254

341

O75437
KRMHTGEKPYKCEEC

ZNF254

481

O75437
DKPHKCNYCDMVFAH

ZBTB26

351

Q9HCK0
KKFKCPYCSFSAMHQ

ZBTB46

416

Q86UZ6
KMHTGDKPYKCNECG

ZNF836

826

Q6ZNA1
QMIHSGEKPYKCNEC

ZNF836

881

Q6ZNA1
KPYKCHDCGKAFFQM

ZNF175

361

Q9Y473
VHMGVKCYKCDVCGK

ZNF222

166

Q9UK12
KLHMREKPYNCEKCG

ZNF222

221

Q9UK12
EKPYNCEKCGKAFMH

ZNF222

226

Q9UK12
IHMGQKPYNCKECGK

ZNF222

306

Q9UK12
HAGEKPYECMKCGKA

ZNF560

566

Q96MR9
VHTSDKPYLCKMCDK

ZIC2

386

O95409
ANKMHKCKFCEYETA

ZFY

511

P08048
VHTKDYPHKCEMCEK

ZFY

651

P08048
YPHKCEMCEKGFHRP

ZFY

656

P08048
SHMGEKAYQCKECGK

ZNF439

291

Q8NDP4
PYKCHCCDMDFKHKS

ZBTB6

381

Q15916
CKKDKAYEGGQLCAM

MXRA5

241

Q9NR99
LMFQYFKKFGDKPCC

NAA25

351

Q14CX7