Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	CNOT6 DDX54 NAV2 NSUN5P2 TRMT61B DHX34 THAP9 YARS2 DHX9	5.25e-05	645	54	9	GO:0140640
GeneOntologyMolecularFunction	regulatory region RNA binding	IREB2 DHX9	7.14e-05	5	54	2	GO:0001069
GeneOntologyMolecularFunction	catalytic activity, acting on RNA	CNOT6 DDX54 NSUN5P2 TRMT61B DHX34 YARS2 DHX9	1.25e-04	417	54	7	GO:0140098
GeneOntologyMolecularFunction	ribosome binding	SEC61A2 EEF2 SEC61A1 DHX9	3.11e-04	120	54	4	GO:0043022
GeneOntologyMolecularFunction	3'-5' DNA helicase activity	NAV2 DHX9	8.41e-04	16	54	2	GO:0043138
GeneOntologyMolecularFunction	helicase activity	DDX54 NAV2 DHX34 DHX9	8.77e-04	158	54	4	GO:0004386
GeneOntologyMolecularFunction	RNA helicase activity	DDX54 DHX34 DHX9	1.23e-03	78	54	3	GO:0003724
GeneOntologyMolecularFunction	ATP-dependent activity, acting on RNA	DDX54 DHX34 DHX9	1.33e-03	80	54	3	GO:0008186
GeneOntologyMolecularFunction	rRNA methyltransferase activity	NSUN5P2 TRMT61B	1.91e-03	24	54	2	GO:0008649
GeneOntologyMolecularFunction	catalytic activity, acting on a rRNA	NSUN5P2 TRMT61B	2.07e-03	25	54	2	GO:0140102
GeneOntologyMolecularFunction	cadherin binding	PROM1 EEF2 GIGYF2 AHSA1 CDH2	2.19e-03	339	54	5	GO:0045296
GeneOntologyMolecularFunction	ribonucleoprotein complex binding	SEC61A2 EEF2 SEC61A1 DHX9	2.33e-03	206	54	4	GO:0043021
GeneOntologyMolecularFunction	protein transmembrane transporter activity	SEC61A2 SEC61A1	2.59e-03	28	54	2	GO:0008320
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH group of donors	PAOX ALDH1L2	2.97e-03	30	54	2	GO:0016645
GeneOntologyCellularComponent	Sec61 translocon complex	SEC61A2 SEC61A1	6.28e-05	5	53	2	GO:0005784
GeneOntologyCellularComponent	translocon complex	SEC61A2 SEC61A1	9.40e-05	6	53	2	GO:0071256
HumanPheno	Recurrent gingivitis	SEC61A1 CXCR2	1.18e-05	2	18	2	HP:0034284
Domain	Plug_translocon	SEC61A2 SEC61A1	8.21e-06	2	54	2	PF10559
Domain	SecY_su_dom	SEC61A2 SEC61A1	8.21e-06	2	54	2	IPR023201
Domain	SecY	SEC61A2 SEC61A1	8.21e-06	2	54	2	PF00344
Domain	SECY_1	SEC61A2 SEC61A1	8.21e-06	2	54	2	PS00755
Domain	SECY_2	SEC61A2 SEC61A1	8.21e-06	2	54	2	PS00756
Domain	-	SEC61A2 SEC61A1	8.21e-06	2	54	2	1.10.3370.10
Domain	Translocon_Sec61/SecY_plug_dom	SEC61A2 SEC61A1	8.21e-06	2	54	2	IPR019561
Domain	SecY_CS	SEC61A2 SEC61A1	8.21e-06	2	54	2	IPR030659
Domain	SecY/SEC61-alpha	SEC61A2 SEC61A1	8.21e-06	2	54	2	IPR002208
Domain	VWA_2	INTS6L INTS14	8.16e-05	5	54	2	PF13519
Domain	DUF1605	DHX34 DHX9	1.09e-03	17	54	2	IPR011709
Domain	OB_NTP_bind	DHX34 DHX9	1.09e-03	17	54	2	PF07717
Domain	HA2	DHX34 DHX9	1.22e-03	18	54	2	SM00847
Domain	HA2	DHX34 DHX9	1.22e-03	18	54	2	PF04408
Domain	Helicase-assoc_dom	DHX34 DHX9	1.22e-03	18	54	2	IPR007502
Domain	DEAD/DEAH_box_helicase_dom	DDX54 DHX34 DHX9	1.23e-03	73	54	3	IPR011545
Domain	DEAD	DDX54 DHX34 DHX9	1.23e-03	73	54	3	PF00270
Domain	LRR_8	CNOT6 TRIL LRRC70 DCN	1.50e-03	171	54	4	PF13855
Domain	FA58C	CNTNAP3B CNTNAP3	1.66e-03	21	54	2	SM00231
Domain	FA58C_3	CNTNAP3B CNTNAP3	1.66e-03	21	54	2	PS50022
Domain	FA58C_1	CNTNAP3B CNTNAP3	1.66e-03	21	54	2	PS01285
Domain	FA58C_2	CNTNAP3B CNTNAP3	1.66e-03	21	54	2	PS01286
Domain	Leu-rich_rpt_typical-subtyp	CNOT6 TRIL LRRC70 DCN	1.70e-03	177	54	4	IPR003591
Domain	LRR_TYP	CNOT6 TRIL LRRC70 DCN	1.70e-03	177	54	4	SM00369
Domain	F5_F8_type_C	CNTNAP3B CNTNAP3	2.17e-03	24	54	2	PF00754
Domain	FA58C	CNTNAP3B CNTNAP3	2.17e-03	24	54	2	IPR000421
Domain	-	CNOT6 TRIL LMOD1 LRRC70 DCN	2.31e-03	321	54	5	3.80.10.10
Domain	L_dom-like	CNOT6 TRIL LMOD1 LRRC70 DCN	2.53e-03	328	54	5	IPR032675
Domain	LRR	CNOT6 TRIL LRRC70 DCN	2.70e-03	201	54	4	PS51450
Domain	LRRNT	TRIL LRRC70 DCN	2.86e-03	98	54	3	IPR000372
Domain	LRRNT	TRIL LRRC70 DCN	2.86e-03	98	54	3	SM00013
Domain	Helicase_C	DDX54 DHX34 DHX9	3.67e-03	107	54	3	PF00271
Domain	HELICc	DDX54 DHX34 DHX9	3.67e-03	107	54	3	SM00490
Domain	LRR_1	CNOT6 TRIL LRRC70 DCN	3.68e-03	219	54	4	PF00560
Domain	Helicase_C	DDX54 DHX34 DHX9	3.76e-03	108	54	3	IPR001650
Domain	FIBRINOGEN_C_1	CNTNAP3B CNTNAP3	3.85e-03	32	54	2	PS00514
Domain	Fibrinogen_a/b/g_C_dom	CNTNAP3B CNTNAP3	3.85e-03	32	54	2	IPR002181
Domain	FIBRINOGEN_C_2	CNTNAP3B CNTNAP3	3.85e-03	32	54	2	PS51406
Domain	HELICASE_CTER	DDX54 DHX34 DHX9	3.86e-03	109	54	3	PS51194
Domain	HELICASE_ATP_BIND_1	DDX54 DHX34 DHX9	3.86e-03	109	54	3	PS51192
Domain	DEXDc	DDX54 DHX34 DHX9	3.86e-03	109	54	3	SM00487
Domain	Helicase_ATP-bd	DDX54 DHX34 DHX9	3.96e-03	110	54	3	IPR014001
Domain	DNA/RNA_helicase_DEAH_CS	DHX34 DHX9	4.59e-03	35	54	2	IPR002464
Domain	DEAH_ATP_HELICASE	DHX34 DHX9	5.40e-03	38	54	2	PS00690
Domain	LAM_G_DOMAIN	CNTNAP3B CNTNAP3	5.40e-03	38	54	2	PS50025
Domain	-	EEF2 DDX54 GNL2 NAV2 HS3ST5 DHX34 DHX9	5.45e-03	746	54	7	3.40.50.300
Pubmed	Control of translocation through the Sec61 translocon by nascent polypeptide structure within the ribosome.	SEC61A2 SEC61A1	2.46e-06	2	55	2	18480044
Pubmed	The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.	CNTNAP3B CNTNAP3	2.46e-06	2	55	2	31150793
Pubmed	Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.	CNTNAP3B CNTNAP3	2.46e-06	2	55	2	26807827
Pubmed	Strong correlation between N-cadherin and CD133 in breast cancer: role of both markers in metastatic events.	PROM1 CDH2	2.46e-06	2	55	2	24962344
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	SEC61A2 HK1 OXCT1 ALDH1L2 TMLHE DDX54 GNL2 TRMT61B ARMCX2 SEC61A1 YARS2 DHX9	3.02e-06	1496	55	12	32877691
Pubmed	Loss of cell-cell contacts induces NF-kappaB via RhoA-mediated activation of protein kinase D1.	NFKB1 PRKD1	7.36e-06	3	55	2	19173301
Pubmed	Correlation between the cystathionine-γ-lyase (CES) and the severity of peptic ulcer disease.	NFKB1 CXCR2	7.36e-06	3	55	2	26060478
Pubmed	Chemotherapy-induced CXC-chemokine/CXC-chemokine receptor signaling in metastatic prostate cancer cells confers resistance to oxaliplatin through potentiation of nuclear factor-kappaB transcription and evasion of apoptosis.	NFKB1 CXCR2	7.36e-06	3	55	2	18780829
Pubmed	Chemokine CXCL8 promotes HIV-1 replication in human monocyte-derived macrophages and primary microglia via nuclear factor-κB pathway.	NFKB1 CXCR2	1.47e-05	4	55	2	24662979
Pubmed	Defective regulation of CXCR2 facilitates neutrophil release from bone marrow causing spontaneous inflammation in severely NF-kappa B-deficient mice.	NFKB1 CXCR2	1.47e-05	4	55	2	20519647
Pubmed	Jak1/Stat3 is an upstream signaling of NF-κB activation in Helicobacter pylori-induced IL-8 production in gastric epithelial AGS cells.	NFKB1 CXCR2	1.47e-05	4	55	2	25837197
Pubmed	N-acetylglucosaminyltransferase V expression levels regulate cadherin-associated homotypic cell-cell adhesion and intracellular signaling pathways.	CDH2 MGAT5B	1.47e-05	4	55	2	14561752
Pubmed	Paralog Studies Augment Gene Discovery: DDX and DHX Genes.	DDX54 DHX34	1.47e-05	4	55	2	31256877
Pubmed	Expression Profiles of the Phosphatase and Tensin Homolog (PTEN), CDH1, and CDH2 Genes, and the Cell Membrane Protein, CD133, in the Ishikawa Human Endometrial Adenocarcinoma Cell Line.	PROM1 CDH2	1.47e-05	4	55	2	31864232
Pubmed	CXCR2-driven ovarian cancer progression involves upregulation of proinflammatory chemokines by potentiating NF-κB activation via EGFR-transactivated Akt signaling.	NFKB1 CXCR2	1.47e-05	4	55	2	24376747
Pubmed	The Sec61 complex is located in both the ER and the ER-Golgi intermediate compartment.	SEC61A2 SEC61A1	1.47e-05	4	55	2	10212142
Pubmed	A key role for early growth response-1 and nuclear factor-kappaB in mediating and maintaining GRO/CXCR2 proliferative signaling in esophageal cancer.	NFKB1 CXCR2	2.45e-05	5	55	2	19435811
Pubmed	Calnexin and other factors that alter translocation affect the rapid binding of ubiquitin to apoB in the Sec61 complex.	SEC61A2 SEC61A1	2.45e-05	5	55	2	9565615
Pubmed	Deletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stress.	SEC61A2 SEC61A1	3.67e-05	6	55	2	16705175
Pubmed	In trans neuregulin3-Caspr3 interaction controls DA axonal bassoon cluster development.	CNTNAP3B CNTNAP3	3.67e-05	6	55	2	34143959
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	SEC61A2 WDR11 TMLHE DDX54 TRMT61B AHSA1 SEC61A1	4.63e-05	606	55	7	36538041
Pubmed	Phospholipase Cϵ Activates Nuclear Factor-κB Signaling by Causing Cytoplasmic Localization of Ribosomal S6 Kinase and Facilitating Its Phosphorylation of Inhibitor κB in Colon Epithelial Cells.	NFKB1 PRKD1	5.13e-05	7	55	2	27053111
Pubmed	The N-terminal domain of the Schaaf-Yang syndrome protein MAGEL2 likely has a role in RNA metabolism.	EEF2 GIGYF2 DHX9	5.41e-05	46	55	3	34265304
Pubmed	Variability in Streptavidin-Sepharose Matrix Quality Can Significantly Affect Proximity-Dependent Biotinylation (BioID) Data.	OXCT1 ALDH1L2 TMLHE DDX54 SEC61A1 YARS2	6.63e-05	438	55	6	32628020
Pubmed	E-Cadherin regulates neural stem cell self-renewal.	PROM1 CDH2	1.10e-04	10	55	2	19321785
Pubmed	LINC00152 Promotes Tumor Progression and Predicts Poor Prognosis by Stabilizing BCL6 From Degradation in the Epithelial Ovarian Cancer.	EEF2 DHX9	1.10e-04	10	55	2	33282727
Pubmed	Therapeutic responses to Roseomonas mucosa in atopic dermatitis may involve lipid-mediated TNF-related epithelial repair.	NFKB1 CXCR2	1.34e-04	11	55	2	32908007
Pubmed	Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.	EEF2 WDR11 ALDH1L2 GNL2 GIGYF2 AHSA1 DHX9	1.41e-04	725	55	7	27025967
Pubmed	The role of assembly in insulin's biosynthesis.	SEC61A2 SEC61A1	1.60e-04	12	55	2	9631292
Pubmed	Insulin receptor substrate-4 interacts with ubiquitin-specific protease 18 to activate the Jak/STAT signaling pathway.	EEF2 DHX9	1.89e-04	13	55	2	29285303
Pubmed	Identification of proteins that interact with the central coiled-coil region of the human protein kinase NEK1.	NEK1 PPP2R5A	1.89e-04	13	55	2	14690447
Pubmed	Afadin controls cell polarization and mitotic spindle orientation in developing cortical radial glia.	PROM1 CDH2	1.89e-04	13	55	2	28482867
Pubmed	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	PROM1 CXCR2	2.21e-04	14	55	2	23470693
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	AHSA1 DMXL1 YARS2	2.42e-04	76	55	3	27542412
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	EEF2 HK1 OXCT1 WDR11 DDX54 NEK7 DGKD DHX34 DHX9	2.52e-04	1353	55	9	29467282
Pubmed	Extracellular human immunodeficiency virus type 1 Tat protein is associated with an increase in both NF-kappa B binding and protein kinase C activity in primary human astrocytes.	NFKB1 PRKD1	2.54e-04	15	55	2	8627654
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	EEF2 DDX54 GNL2 GIGYF2 DHX34 YARS2 DHX9	2.72e-04	807	55	7	22681889
Pubmed	[HIV-1 Tat protein induces IL-10 production by human monocytes: implications of the PKC and calcium pathway].	NFKB1 PRKD1	2.90e-04	16	55	2	11833470
Pubmed	Quantitative Lys-ϵ-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1.	EEF2 GIGYF2 AHSA1 SEC61A1 DHX9	3.25e-04	377	55	5	25147182
Pubmed	Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis.	EEF2 PRKD1 DHX9	3.26e-04	84	55	3	19135240
Pubmed	Cell adhesion molecule contactin-associated protein 3 is expressed in the mouse basal ganglia during early postnatal stages.	CNTNAP3B CNTNAP3	3.29e-04	17	55	2	26389685
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	EEF2 HK1 DDX54 GNL2 GIGYF2 AHSA1 SEC61A1 YARS2 DHX9	3.68e-04	1425	55	9	30948266
Pubmed	Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors.	PROM1 CDH2	3.70e-04	18	55	2	17589506
Pubmed	Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.	PROM1 EEF2 HK1 OXCT1 ARMCX2 YARS2 DHX9	3.96e-04	859	55	7	31536960
Pubmed	MARCKS modulates radial progenitor placement, proliferation and organization in the developing cerebral cortex.	PROM1 CDH2	4.13e-04	19	55	2	19666823
Pubmed	Proteome analysis of the circadian clock protein PERIOD2.	EEF2 HK1 PRKD1	4.53e-04	94	55	3	35122331
Pubmed	Tat protein of human immunodeficiency virus type 1 induces interleukin-10 in human peripheral blood monocytes: implication of protein kinase C-dependent pathway.	NFKB1 PRKD1	4.58e-04	20	55	2	11044099
Pubmed	Crumbs 2 prevents cortical abnormalities in mouse dorsal telencephalon.	PROM1 CDH2	4.58e-04	20	55	2	26802325
Pubmed	Defining the membrane proteome of NK cells.	CNOT6 EEF2 WDR11 DDX54 GNL2 GIGYF2 DHX34 DHX9	4.74e-04	1168	55	8	19946888
Pubmed	WWP2-WWP1 ubiquitin ligase complex coordinated by PPM1G maintains the balance between cellular p73 and ΔNp73 levels.	EEF2 TMLHE DHX9	4.97e-04	97	55	3	25071155
Pubmed	ATP6AP2 variant impairs CNS development and neuronal survival to cause fulminant neurodegeneration.	PROM1 CDH2	5.06e-04	21	55	2	30985297
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	EEF2 DDX54 GIGYF2 DHX9	5.20e-04	234	55	4	36243803
Pubmed	Loss of RhoA in neural progenitor cells causes the disruption of adherens junctions and hyperproliferation.	PROM1 CDH2	5.56e-04	22	55	2	21502507
Pubmed	FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.	CNTNAP3B CNTNAP3	5.56e-04	22	55	2	26494785
Pubmed	Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene.	NEK1 DDX54	5.56e-04	22	55	2	22305495
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	HK1 OXCT1 VAT1L AHSA1 SEC61A1 DHX9	6.25e-04	665	55	6	30457570
Pubmed	Network organization of the human autophagy system.	SEC61A2 HK1 WDR11 NEK7 TRMT61B	6.35e-04	437	55	5	20562859
Pubmed	Functional proteomic analysis of human nucleolus.	DDX54 GNL2 DHX9	6.43e-04	106	55	3	12429849
Pubmed	The splicing factor FUBP1 is required for the efficient splicing of oncogene MDM2 pre-mRNA.	EEF2 DHX9	6.63e-04	24	55	2	24798327
Pubmed	The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface.	PROM1 CDH2	6.63e-04	24	55	2	16892058
Pubmed	SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.	PPP2R5A DDX54 DHX34 DHX9	6.67e-04	250	55	4	33536335
Pubmed	A whole genome screen for HIV restriction factors.	ALDH1L2 DGKD NPEPL1	6.79e-04	108	55	3	22082156
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	EEF2 DDX54 GNL2 GIGYF2 SEC61A1 DHX9	6.91e-04	678	55	6	30209976
Pubmed	Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.	EEF2 HK1 AHSA1 SEC61A1	7.28e-04	256	55	4	35777956
Pubmed	Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.	NFKB1 GNL2 NAV2 GIGYF2	7.39e-04	257	55	4	30945288
Pubmed	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	DENND1B NFKB1	7.79e-04	26	55	2	21399635
Pubmed	Angiopoietin-like 2 is essential to aortic valve development in mice.	NFKB1 DCN	7.79e-04	26	55	2	36414704
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	EEF2 WDR11 ALDH1L2 DDX54 GNL2 AHSA1 DHX9	8.17e-04	971	55	7	33306668
Pubmed	Mechanism of HIV-1-TAT induction of interleukin-1beta from human monocytes: Involvement of the phospholipase C/protein kinase C signaling cascade.	NFKB1 PRKD1	8.40e-04	27	55	2	20336759
Pubmed	TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1.	SEC61A2 NFKB1 SEC61A1	8.57e-04	117	55	3	36898370
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	EEF2 DDX54 GNL2 AHSA1 SEC61A1 YARS2 DHX9	9.10e-04	989	55	7	36424410
Pubmed	Repression of rRNA transcription by PARIS contributes to Parkinson's disease.	EEF2 DDX54 AHSA1 DHX9	9.12e-04	272	55	4	25315684
Pubmed	Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons.	CNTNAP3B CNTNAP3	9.70e-04	29	55	2	31491374
Pubmed	AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.	EEF2 HK1 TMLHE CDH2 DHX9	1.00e-03	484	55	5	31995728
Pubmed	A Noncanonical Role of Fructose-1, 6-Bisphosphatase 1 Is Essential for Inhibition of Notch1 in Breast Cancer.	EEF2 NFKB1 GIGYF2 DHX9	1.10e-03	286	55	4	32041737
Pubmed	BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs.	EEF2 DHX9	1.11e-03	31	55	2	23086144
Pubmed	Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation.	DDX54 AHSA1 DHX9	1.14e-03	129	55	3	28973437
Pubmed	Splicing Regulator p54nrb /Non-POU Domain-Containing Octamer-Binding Protein Enhances Carcinogenesis Through Oncogenic Isoform Switch of MYC Box-Dependent Interacting Protein 1 in Hepatocellular Carcinoma.	EEF2 DHX9	1.18e-03	32	55	2	31815296
Pubmed	The tumor suppressor PP2A Abeta regulates the RalA GTPase.	EEF2 PPP2R5A	1.18e-03	32	55	2	17540176
Pubmed	Genetic variations in humans associated with differences in the course of hepatitis C.	NFKB1 CXCR2	1.18e-03	32	55	2	15063762
Pubmed	Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome.	EEF2 DHX9	1.18e-03	32	55	2	18809582
Pubmed	Global identification of modular cullin-RING ligase substrates.	CCNF SEC61A1 DHX9	1.27e-03	134	55	3	21963094
Pubmed	Biological insights from 108 schizophrenia-associated genetic loci.	NEK1 GIGYF2 IREB2 PRKD1	1.36e-03	303	55	4	25056061
Pubmed	Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors.	PROM1 CDH2	1.41e-03	35	55	2	28808228
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CNOT6 NAV2 KDM7A NPEPL1 DHX34	1.49e-03	529	55	5	14621295
Pubmed	LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway.	EEF2 OXCT1 DHX9	1.50e-03	142	55	3	30809309
Pubmed	Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles.	EEF2 CDH2	1.58e-03	37	55	2	19865483
Pubmed	Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis.	EEF2 HK1	1.58e-03	37	55	2	9798653
Interaction	ALDH1L2 interactions	CCNF INTS14 WDR11 ALDH1L2	5.14e-06	42	55	4	int:ALDH1L2
Cytoband	1q31.3	DENND1B NEK7	1.67e-04	16	55	2	1q31.3
GeneFamily	Integrator complex	INTS6L INTS14	2.95e-04	15	31	2	1366
GeneFamily	DEAH-box helicases	DHX34 DHX9	3.36e-04	16	31	2	500
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000	INTS6L SEC61A2 DENND1B EXD1 TMLHE NAV2 GIGYF2 PRKD1 SEC61A1 DMXL1	3.25e-05	795	55	10	gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000	CNOT6 INTS6L DENND1B TMLHE NAV2 GIGYF2 PRKD1 SEC61A1 CDH2 DMXL1	3.57e-05	804	55	10	gudmap_developingGonad_e12.5_ovary_1000
ToppCell	3'_v3-Lung-Lymphocytic_Invariant-Inducer-like-ILC3\|Lung / Manually curated celltypes from each tissue	EXD1 NFKB1 RPS6KA6 PRKD1 CDH2	1.99e-06	167	55	5	0614d077b47a87f726068615548d0b0a216627be
ToppCell	pdx-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CNTNAP3B CNTNAP3 NAV2 KDM7A CDH2	3.03e-06	182	55	5	7b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCell	Neuronal-Inhibitory-iB\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B PROM1 CNTNAP3 DGKD DCN	4.79e-06	200	55	5	45ddc5ef2caa87ada88327b63ba9b150a6bb3aa5
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CNTNAP3B ALDH1L2 CNTNAP3 CXCR2	2.86e-05	142	55	4	191a13bba143ecdfc2bfd797c3ac191481388298
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CNTNAP3B ALDH1L2 CNTNAP3 CXCR2	2.94e-05	143	55	4	b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCell	Paneth_cell\|World / shred on cell type and cluster	CNTNAP3B PROM1 ALDH1L2 SEC61A1	4.56e-05	160	55	4	d787b7cdb8c3f677ac9c4934a5df9cc194df3987
ToppCell	C_07\|World / shred on cell type and cluster	CNTNAP3B PROM1 ALDH1L2 SEC61A1	4.56e-05	160	55	4	b7c5a8a1c85da92e1945721b6887b32fad7b76b8
ToppCell	Pericytes-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	LMOD1 VAT1L DCN CDH2	5.91e-05	171	55	4	bbc8d9fc83d37c9250345b1e76776610799de9ae
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PROM1 VILL NEK7 DKKL1	6.46e-05	175	55	4	0992de1c7bffcb6890584357a7a0a8955927da6c
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CNTNAP3B NFKB1 NAV2 CDH2	6.90e-05	178	55	4	a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	CNTNAP3B CNTNAP3 LMOD1 KDM7A	7.05e-05	179	55	4	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ALDH1L2 RPS6KA6 DCN CDH2	7.52e-05	182	55	4	ba066ff9029cc052b76e2330ec168cb2e9b7e498
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRIL CNTNAP3B CNTNAP3 LRRC70	7.52e-05	182	55	4	53c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CNTNAP3 HS3ST5 LMOD1 DCN	7.68e-05	183	55	4	6b5eef96b28911c752a8b6c0975918c4572cec38
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PROM1 VILL NEK7 DKKL1	7.68e-05	183	55	4	7eaa6ef7c6cf848fd6489f97677f4406318da22f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 NEK7 DGKD	8.01e-05	185	55	4	e87e6e097dc29ece8aea671935bde281b99b93ea
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRIL CNTNAP3B CNTNAP3 LRRC70	8.18e-05	186	55	4	40070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PROM1 CNTNAP3 LMOD1 DCN	8.35e-05	187	55	4	173f029dcf32af008f517912f6d110a33a9e98cf
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CNTNAP3B PROM1 ACMSD CDH2	8.70e-05	189	55	4	3b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	INTS6L NAV2 LMOD1 VAT1L	8.70e-05	189	55	4	0abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 DGKD DCN	8.88e-05	190	55	4	d19bc44310c53726e2f5f6a2bd377bbbf1d1983f
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 NEK7 DGKD	8.88e-05	190	55	4	39ab890104b4264c68a968f920f4ccd84f0bc681
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PROM1 CNTNAP3 LMOD1 DCN	8.88e-05	190	55	4	c01a8bfb9fbc0e6f37d7e9be25512eda63acabbc
ToppCell	droplet-Mammary_Gland-nan-18m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PROM1 VILL NEK7 DKKL1	9.06e-05	191	55	4	c21e7904e06a5c90176f935f6822dbb5a1aa6755
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PROM1 CNTNAP3 LMOD1 DCN	9.06e-05	191	55	4	89d03c4133dda852a3713c0902a7d67941cf5b21
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B PROM1 CNTNAP3 DGKD	9.06e-05	191	55	4	782bc7946417549ffd39e5b596db659436fa01ba
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 DGKD DCN	9.43e-05	193	55	4	53bcd50892c379b2a571751f6eb1062436339fe7
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 NAV2 DCN	9.43e-05	193	55	4	8b77625bf3c87d39767fb391d1beaca4ab02342b
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	CNOT6 DENND1B GIGYF2 IREB2	9.43e-05	193	55	4	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 DGKD DCN	9.43e-05	193	55	4	5581a5ebcd21a2a8062ccfb917f088ec67a10a9c
ToppCell	facs-Thymus-nan-3m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNOT6 EEF2 PPP2R5A DGKD	9.62e-05	194	55	4	f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCell	facs-Thymus-nan-3m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNOT6 EEF2 PPP2R5A DGKD	9.62e-05	194	55	4	66c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCell	facs-Thymus-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CNOT6 EEF2 PPP2R5A DGKD	9.62e-05	194	55	4	cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TRIL PROM1 NEK7 DCN	9.82e-05	195	55	4	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D122\|Adult / Lineage, Cell type, age group and donor	NAV2 LMOD1 PRKD1 DCN	9.82e-05	195	55	4	aa0add081881d349099d12efca5cdee098038d4e
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CNTNAP3B CNTNAP3 NAV2 LMOD1	1.02e-04	197	55	4	f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PROM1 CNTNAP3 LMOD1 DCN	1.02e-04	197	55	4	398a66c06df63567b176ab2cc85e27837e94d0d9
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRIL PROM1 LMOD1 DCN	1.02e-04	197	55	4	888f3b14133e078570ce4ad73d9a9ee3137f9cac
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)-FRZB\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B PROM1 CNTNAP3 DGKD	1.08e-04	200	55	4	e79d93d55b25804f2608185168da472301b6ebca
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	PROM1 OXCT1 LMOD1 DCN	1.08e-04	200	55	4	593bf6a7c557437db9a9249a5058a46014179ef6
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-HPGD-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B CNTNAP3 NAV2 DCN	1.08e-04	200	55	4	1ec2f322f936d2501330c53bb7c9390216c50cd1
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PROM1 EEF2 LMOD1 DCN	1.08e-04	200	55	4	dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-HPGD--L3-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B CNTNAP3 NAV2 DCN	1.08e-04	200	55	4	e250b2e45ef869f81cc40cc41f53d1e54e7848aa
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)-FRZB--L2-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B PROM1 CNTNAP3 DGKD	1.08e-04	200	55	4	5ec469267747dce3601c1d8ad01af89fa5b29acc
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-HPGD\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B CNTNAP3 NAV2 DCN	1.08e-04	200	55	4	dea96adbd9a77fe50ff397d4bdeb4dc8f50de3b7
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)-FRZB-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CNTNAP3B PROM1 CNTNAP3 DGKD	1.08e-04	200	55	4	320d5a3a1e7da2fa8f1a164e29e180ec8ac9889c
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LMOD1 DCN SLC2A5	2.01e-04	92	55	3	84ac97a16920b912a67ea80e71146eddf9dfa92f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EXD1 PRKD1 VAT1L	6.45e-04	137	55	3	761cc0e2b4971e98f6d0691d4575b5cd208b602d
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	EXD1 CDH2 CXCR2	8.23e-04	149	55	3	c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	EXD1 CDH2 CXCR2	8.23e-04	149	55	3	a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crhr2_Efemp1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CNTNAP3 NEK7 VAT1L	9.06e-04	154	55	3	a2adaa4a6cd8708cd579b8efbeb4ff2131c5482e
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	DENND1B NFKB1 THAP9	9.23e-04	155	55	3	c4dc0fa1d0e657753a56939eb4829fb60382c17f
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Fibroblasts-Pericyte_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GNL2 DHX34 CDH2	9.75e-04	158	55	3	7f5426585d0d299d2b48e5fcb349950feffdef33
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PAOX LRRC70 DHX34	9.93e-04	159	55	3	f7bccfeffa737f151417bf52ea45111b0957bce9
ToppCell	LPS-antiTNF-Myeloid-Monocytes,_Macrophages-Neutrophils\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CCNF THAP9 SLC2A5	1.01e-03	160	55	3	5d8d97c3da5837ba5fe743d2f8438f5cb7cea64b
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TRIL PROM1 NAV2	1.03e-03	161	55	3	b19f82dd98a3064581793711bb70373f18abecd9
ToppCell	facs-Skin-Anagen-3m-Epithelial-inner_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PROM1 LMOD1 DCN	1.03e-03	161	55	3	8d2987271da52fd8353557ac6faa4f7a4be0ed2a
ToppCell	Influenza_Severe-gd_T\|World / Disease group and Cell class	CNTNAP3B CNTNAP3 LRRC70	1.03e-03	161	55	3	b3cdaed4d58d57e3c5dbc904a09388f3bf949407
ToppCell	367C-Lymphocytic-ILC-ILC-3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NAV2 THAP9 YARS2	1.03e-03	161	55	3	8de421c61f4d5a6e05fdb20e4d230e2db98ee4d5
ToppCell	Influenza_Severe-Neutrophil\|Influenza_Severe / Disease group and Cell class	CNTNAP3B CNTNAP3 CXCR2	1.03e-03	161	55	3	98c95b1b85d5427415af2ca8fb14849e97f6e8b5
ToppCell	BL-critical-LOC-Myeloid-Basophil\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	INTS6L WDR11 DGKD	1.05e-03	162	55	3	25ec9df914445b4daae4fd28fd0e60b64797c46d
ToppCell	10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PROM1 LRRC70 SLC2A5	1.07e-03	163	55	3	edca1d1a345109dbdeb7ee5464faefab1993fdb2
ToppCell	Basal_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	NEK1 OXCT1 DCN	1.09e-03	164	55	3	b15a26130a1ea1b370b6e3be21f02a0d6aaf6b3c
ToppCell	wk_20-22-Hematologic-Myeloid-HSC/ELP\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PROM1 LRRC70 SLC2A5	1.09e-03	164	55	3	3c07d8f53511f269540bf032738a4ada35650b18
ToppCell	343B-Myeloid-Dendritic-cDC_activated\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SEC61A2 CDH2 SLC2A5	1.09e-03	164	55	3	eae6d440877b292ad18dc4bd02802dda5b2f9c60
ToppCell	facs-Marrow-B-cells-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ALDH1L2 ACMSD CDH2	1.10e-03	165	55	3	361a605d8f833d9ec54b120480dce397da35f9c3
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEC61A2 PROM1 NFKB1	1.12e-03	166	55	3	3b67064a5149e72f895344d938c64b8ff65247f5
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PROM1 ALDH1L2 SLC2A5	1.12e-03	166	55	3	f4698fd08965936d51695d571bd10fb77330d916
ToppCell	facs-Heart-LA-18m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VILL ALDH1L2 DKKL1	1.14e-03	167	55	3	8340f7075d00dccb304cfd4c9b5711ca6dbf7cce
ToppCell	343B-Myeloid-Dendritic-cDC_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CCNF OXCT1 PCDHB3	1.14e-03	167	55	3	3461d14e36f09ddc6ee5549ca4797e16d3f37fcc
ToppCell	facs-Heart-LA-18m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VILL ALDH1L2 DKKL1	1.14e-03	167	55	3	8ce8d93c79ac6a3f52252b4cec53378c362bfe0a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c3-CST7\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	DCN DHX34 CXCR2	1.14e-03	167	55	3	9b9b4cad0b35d121256176600ea4705759c105d3
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_vein-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTNAP3B CNTNAP3 PCDHB3	1.14e-03	167	55	3	d7fe24cdc4b55a9555ce9e20699f5036b88148e9
ToppCell	Influenza_Severe-Neutrophil\|World / Disease group and Cell class	CNTNAP3B CNTNAP3 CXCR2	1.18e-03	169	55	3	6e8e2580e19c96bcf7fa6a6d8c183df65f428396
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CCNF HS3ST5 THAP9	1.18e-03	169	55	3	2833a8a7094e4d407eb923f2bc59b9b112c6bae4
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-T_cells-ILC3\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NFKB1 AHSA1 MGAT5B	1.18e-03	169	55	3	d4a0bd792bddfa34332d7dc432ce253f50d98c6f
ToppCell	RA-01._Fibroblast_I\|RA / Chamber and Cluster_Paper	VILL NAV2 DCN	1.18e-03	169	55	3	6373562ab3b1765060212a6a53d6543e7e942e80
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NAV2 LMOD1 DCN	1.18e-03	169	55	3	a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCell	BL-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RPS6KA6 PRKD1 CDH2	1.20e-03	170	55	3	b465df2dac6b4e98b4ede6ad0c6347656757885c
ToppCell	facs-Marrow-Granulocytes-24m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPS6KA6 NAV2 SLC2A5	1.20e-03	170	55	3	8d3c51364a332020810836e2055c60893c10d7f3
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3 HS3ST5 SLC2A5	1.20e-03	170	55	3	cf22a843ae2d9cd6693507fed2b7c6a45abea10e
ToppCell	356C-Myeloid-Dendritic-cDC_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CCNF NAV2 SLC2A5	1.22e-03	171	55	3	b113fbebb89056af0b9c775d2fb6552206a80467
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	PROM1 ALDH1L2 SLC2A5	1.24e-03	172	55	3	e9b97f37bb1732ad9aa89c5e9b513d14022801ac
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKD1 VAT1L MGAT5B	1.27e-03	173	55	3	2b448acd5e584f24567204c31b8d74715e92f32a
ToppCell	3'-Airway_Nasal-Endothelial-Blood_vessel_EC\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B CDH2 MGAT5B	1.27e-03	173	55	3	b7d8702409b86fbc8741a472b84d509ba261a852
ToppCell	3'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B CDH2 MGAT5B	1.27e-03	173	55	3	b83c9e274999c9325908616cee4a89d425c8c4ed
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D122\|Adult / Lineage, Cell type, age group and donor	TRIL CNTNAP3B CNTNAP3	1.27e-03	173	55	3	dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INTS6L VILL GIGYF2	1.27e-03	173	55	3	c31076c725f4cd912c56903592a2d9356ae59f54
ToppCell	3'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B CDH2 MGAT5B	1.27e-03	173	55	3	0068c059ef118b5ef85c5b01ad8680ce11493aa5
ToppCell	3'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B CDH2 MGAT5B	1.27e-03	173	55	3	3c96e269ca7b7029f533268f68ca4466edd20edd
ToppCell	3'-Airway_Nasal-Endothelial\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B CDH2 MGAT5B	1.27e-03	173	55	3	383edcd3bb14d3934506260dbbac7167282546af
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INTS6L VILL GIGYF2	1.27e-03	173	55	3	a4ed191cfdf6588b7f3672995bf0a4fe9e4b8df6
ToppCell	severe_influenza-Neutrophil\|severe_influenza / disease group, cell group and cell class (v2)	CNTNAP3B CNTNAP3 CXCR2	1.27e-03	173	55	3	615e266419b9f06e964eff73cb466f05451ba0dd
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKD1 VAT1L MGAT5B	1.27e-03	173	55	3	5086edc29c5a6137ca09877929a1317f9739c801
ToppCell	severe_influenza-Neutrophil\|World / disease group, cell group and cell class (v2)	CNTNAP3B CNTNAP3 CXCR2	1.29e-03	174	55	3	f9f07436b7d3f190800cd85d229f007032f391e1
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B CNTNAP3 VAT1L	1.29e-03	174	55	3	321c6cae614d28feeee266eeb3499f2053ab79e0
ToppCell	TCGA-Prostate-Solid_Tissue_Normal-Prostate_normal_tissue-Prostate_normal_tissue\|TCGA-Prostate / Sample_Type by Project: Shred V9	ALDH1L2 TMLHE CXCR2	1.29e-03	174	55	3	de6c1ebca36ec8060ddcafc270c45d6ab1caec2c
ToppCell	TCGA-Prostate-Solid_Tissue_Normal\|TCGA-Prostate / Sample_Type by Project: Shred V9	ALDH1L2 TMLHE CXCR2	1.29e-03	174	55	3	abdb5a89118b82bb64469fc41c163bd2b282b0c0
ToppCell	TCGA-Prostate-Solid_Tissue_Normal-Prostate_normal_tissue\|TCGA-Prostate / Sample_Type by Project: Shred V9	ALDH1L2 TMLHE CXCR2	1.29e-03	174	55	3	0dde0e9ef987c52cb29a238f15568a83424d02f6
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAV2 LMOD1 DCN	1.31e-03	175	55	3	1799a7be623dc3bf53ba580a7c47d2619969d708
Disease	autosomal recessive intellectual developmental disorder (implicated_via_orthology)	CNTNAP3B CNTNAP3	8.80e-05	8	53	2	DOID:0060308 (implicated_via_orthology)
Disease	Nephritis, Interstitial	DCN SEC61A1	8.52e-04	24	53	2	C0027707
Disease	Carcinoma, Granular Cell	EEF2 NFKB1 PRKD1	1.20e-03	116	53	3	C0205644
Disease	Adenocarcinoma, Tubular	EEF2 NFKB1 PRKD1	1.20e-03	116	53	3	C0205645
Disease	Adenocarcinoma, Oxyphilic	EEF2 NFKB1 PRKD1	1.20e-03	116	53	3	C0205642
Disease	Carcinoma, Cribriform	EEF2 NFKB1 PRKD1	1.20e-03	116	53	3	C0205643
Disease	Adenocarcinoma, Basal Cell	EEF2 NFKB1 PRKD1	1.20e-03	116	53	3	C0205641
Disease	Adenocarcinoma	EEF2 NFKB1 PRKD1	1.20e-03	116	53	3	C0001418
Disease	Large cell carcinoma of lung	NEK1 RPS6KA6	1.52e-03	32	53	2	C0345958
Disease	melanoma (is_implicated_in)	NFKB1 KDM7A	1.71e-03	34	53	2	DOID:1909 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LIKGKLVFFLNSGNA	CNTNAP3	236	Q9BZ76
GEASINNRKGKLIFF	AHSA1	66	O95433
NKLKLALIGQSLFGQ	ALDH1L2	21	Q3SY69
KNKLKAGNALAFLGL	ACMSD	316	Q8TDX5
ALKNAFSLLGKQRFE	DMXL1	1681	Q9Y485
ANFFRLLSQGGGKIK	ARMCX2	511	Q7L311
EFAGFQIGLLNKDLK	INTS6L	491	Q5JSJ4
RGTFANIKLFNKFIG	IREB2	796	P48200
GKILKLNRNGHARFF	KDM7A	926	Q6ZMT4
YCKKLLKGLFRQGLQ	PRKD1	286	Q15139
KGAFIQLLRQFGKLH	GNL2	291	Q13823
GDLFKRINAQKGVLF	NEK1	86	Q96PY6
VKGFLFGKNFRIDKA	EXD1	351	Q8NHP7
AQKLHFLQRGGLKQL	DDX54	836	Q8TDD1
LLQGFSRLFLKGNLL	DKKL1	51	Q9UK85
QQLLRKAKLFIGFGF	MGAT5B	521	Q3V5L5
LQFKRGLLHEFRKGN	HS3ST5	61	Q8IZT8
GKGILAIFRALLQNN	LMOD1	401	P29536
LGAFRAAIKQGFKDN	NPEPL1	291	Q8NDH3
LKGLNNLAKLGLSFN	DCN	241	P07585
LANFRIEKKIGRGQF	NEK7	31	Q8TDX7
FIGQKFRHGLLKILA	CXCR2	316	P25025
AALLKNQGKIFAFDL	NSUN5P2	61	Q63ZY6
FGFAKQLRGENGLLL	RPS6KA6	566	Q9UK32
NILIDFTKKGFLFRG	HK1	756	P19367
NNNFIKRLDPGIFKG	LRRC70	116	Q7Z2Q7
LLKLFQGVNKAQDGF	GIGYF2	1121	Q6Y7W6
GNLKLFERAAEKGNF	CCNF	86	P41002
RKAALAFGFLDLLKG	INTS14	441	Q96SY0
GDNQGVKFLRRFKQL	DGKD	331	Q16760
LNFIKQSKDGAGFLI	EEF2	86	P13639
LDFGQKQAFGRLAKL	DHX34	141	Q14147
FKQFIDGRLAKLNAG	DENND1B	381	Q6P3S1
RLNGDFAQLNLKIKF	CDH2	656	P19022
LGKLFQLQTLGLKGN	CNOT6	116	Q9ULM6
LIKGKLVFFLNSGNA	CNTNAP3B	236	Q96NU0
KLLRLGGIGQFLAKA	DHX9	806	Q08211
KGFLIANLAKDLGLR	PCDHB3	41	Q9Y5E6
AIRKIGFGTNNKIFL	PAOX	311	Q6QHF9
PKDRALFNGAQKLFG	SEC61A2	106	Q9H9S3
QGLLAAQKARGLFKD	YARS2	36	Q9Y2Z4
PLVNKFGRKGALLFN	SLC2A5	91	P22732
EIRNGNLKAILGLFF	NAV2	171	Q8IVL1
LKVNLNIFLLGAAGR	PROM1	601	O43490
NFGLGLLLRSKQIKR	OXCT1	96	P55809
GKFLGLRAFIRKQIN	PPP2R5A	216	Q15172
TKFKKLFRLNNFGLL	TRMT61B	166	Q9BVS5
IKGKQKLGFLGFLLN	THAP9	566	Q9H5L6
PKDRALFNGAQKLFG	SEC61A1	106	P61619
IRFLGKNAFAQLGKL	TRIL	191	Q7L0X0
KNAFAQLGKLRFLNL	TRIL	196	Q7L0X0
FSLLNLLFKQGRAGL	VAT1L	316	Q9HCJ6
NSFNKGDIFLLDLGK	VILL	156	O15195
SLKNLGFKQGAVLFA	WDR11	1186	Q9BZH6
GLKKFLQNFLLYGIA	TMLHE	176	Q9NVH6
AQKLGLGILNNAFRL	NFKB1	836	P19838