Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondermatan 4-sulfotransferase

CHST14 CHST11

8.56e-065192GO:0001537
GeneOntologyMolecularFunctionlipid phosphatase activity

PLPP4 INPP5K

1.45e-0419192GO:0042577
GeneOntologyMolecularFunctionolfactory receptor activity

OR1E3 OR51S1 OR2L8 OR2L3

6.41e-04431194GO:0004984
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR1E3 OR51S1 INPP5K OR2L8 OR2L3

1.16e-03884195GO:0004930
GeneOntologyMolecularFunctionsulfotransferase activity

CHST14 CHST11

1.24e-0355192GO:0008146
GeneOntologyMolecularFunctiontransferase activity, transferring sulphur-containing groups

CHST14 CHST11

2.22e-0374192GO:0016782
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR1E3 OR51S1 INPP5K OR2L8 OR2L3

7.40e-031353195GO:0004888
GeneOntologyMolecularFunctionserine-type endopeptidase activity

APEH HABP2

1.38e-02190192GO:0004252
GeneOntologyMolecularFunctionserine-type peptidase activity

APEH HABP2

1.63e-02207192GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

APEH HABP2

1.70e-02212192GO:0017171
DomainYIPPEE

YPEL1 YPEL2

7.79e-065172PS51792
DomainCarb_sulfotransferase-rel

CHST14 CHST11

1.63e-057172IPR018011
DomainYippee-Mis18

YPEL1 YPEL2

2.18e-058172PF03226
DomainYippee/Mis18/Cereblon

YPEL1 YPEL2

2.18e-058172IPR004910
DomainSulfotransferase

CHST14 CHST11

5.12e-0512172IPR005331
DomainSulfotransfer_2

CHST14 CHST11

5.12e-0512172PF03567
DomainOlfact_rcpt

OR51S1 OR2L8 OR2L3

5.05e-03393173IPR000725
DomainEGF_CA

HABP2 THBS4

5.40e-03122172SM00179
DomainEGF-like_Ca-bd_dom

HABP2 THBS4

5.57e-03124172IPR001881
DomainEGF

HABP2 THBS4

5.75e-03126172PF00008
DomainEGF

HABP2 THBS4

1.89e-02235172SM00181
DomainEGF_3

HABP2 THBS4

1.89e-02235172PS50026
DomainEGF-like_dom

HABP2 THBS4

2.11e-02249172IPR000742
DomainGPCR_Rhodpsn_7TM

OR51S1 OR2L8 OR2L3

2.15e-02670173IPR017452
DomainEGF_1

HABP2 THBS4

2.21e-02255172PS00022
Domain7tm_1

OR51S1 OR2L8 OR2L3

2.21e-02677173PF00001
DomainG_PROTEIN_RECEP_F1_1

OR51S1 OR2L8 OR2L3

2.28e-02685173PS00237
DomainEGF-like_CS

HABP2 THBS4

2.30e-02261172IPR013032
DomainG_PROTEIN_RECEP_F1_2

OR51S1 OR2L8 OR2L3

2.33e-02691173PS50262
DomainGPCR_Rhodpsn

OR51S1 OR2L8 OR2L3

2.34e-02692173IPR000276
DomainEGF_2

HABP2 THBS4

2.37e-02265172PS01186
PathwayKEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_CHONDROITIN_SULFATE

CHST14 CHST11

2.41e-0422152M19166
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR1E3 OR51S1 OR2L8 OR2L3

7.95e-04417154M4072
PathwayWP_GLYCOSAMINOGLYCAN_SYNTHESIS_IN_FIBROBLASTS

CHST14 CHST11

8.46e-0441152M48095
PathwayREACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM

CHST14 CHST11

1.16e-0348152MM14696
PathwayREACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM

CHST14 CHST11

1.26e-0350152M678
Pubmed

Specificities of three distinct human chondroitin/dermatan N-acetylgalactosamine 4-O-sulfotransferases demonstrated using partially desulfated dermatan sulfate as an acceptor: implication of differential roles in dermatan sulfate biosynthesis.

CHST14 CHST11

8.48e-07319212847091
Pubmed

Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species.

YPEL1 YPEL2

2.82e-06519215556292
Pubmed

Dermatan sulfotransferase Chst14/D4st1, but not chondroitin sulfotransferase Chst11/C4st1, regulates proliferation and neurogenesis of neural progenitor cells.

CHST14 CHST11

4.24e-06619222159417
Pubmed

Expression of multiple chondroitin/dermatan sulfotransferases in the neurogenic regions of the embryonic and adult central nervous system implies that complex chondroitin sulfates have a role in neural stem cell maintenance.

CHST14 CHST11

7.90e-06819218079434
Pubmed

YPEL5 protein of the YPEL gene family is involved in the cell cycle progression by interacting with two distinct proteins RanBPM and RanBP10.

YPEL1 YPEL2

1.27e-051019220580816
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR1E3 OR51S1 OR2L8 OR2L3

3.10e-0534019411802173
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR1E3 OR51S1 OR2L8 OR2L3

3.10e-0534019411875048
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR1E3 OR51S1 OR2L8 OR2L3

3.21e-0534319432295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR1E3 OR51S1 OR2L8 OR2L3

3.32e-0534619414611657
Cytoband15q15.1

CHST14 DISP2

1.73e-044719215q15.1
Cytoband17p13.3

OR1E3 INPP5K

6.08e-048819217p13.3
Cytoband1q44

OR2L8 OR2L3

9.47e-041101921q44
CytobandEnsembl 112 genes in cytogenetic band chr1q44

OR2L8 OR2L3

1.28e-03128192chr1q44
CytobandEnsembl 112 genes in cytogenetic band chr15q15

CHST14 DISP2

1.68e-03147192chr15q15
CytobandEnsembl 112 genes in cytogenetic band chr17p13

OR1E3 INPP5K

8.90e-03346192chr17p13
GeneFamilyYippee like family

YPEL1 YPEL2

4.03e-0651221130
GeneFamilySulfotransferases, membrane bound

CHST14 CHST11

2.66e-0437122763
GeneFamilyOlfactory receptors, family 2

OR2L8 OR2L3

2.45e-03113122149
Diseasecorneal resistance factor

HABP2 THBS4 ZNF516

2.06e-03451173EFO_0010067

Protein segments in the cluster

PeptideGeneStartEntry
YCISYHLCPHPDRLS

DISP2

1036

A7MBM2
CAHTVYVLHIPYCQS

OR2L3

156

Q8NG85
PVCLLCNYSTHVLYH

LRRC9

206

Q6ZRR7
CNYSTHVLYHLPCLQ

LRRC9

211

Q6ZRR7
CAHTVYVLHIPYCRS

OR2L8

156

Q8NGY9
YCLPQVLTHSYCLHP

OR51S1

176

Q8NGJ8
CYRQHYPPLANTACH

PLPP4

221

Q5VZY2
LITQSPPYYRCVCKH

HABP2

126

Q14520
YYVSIINCHLPPHIS

INPP5K

141

Q9BT40
HCYVAICFPLHYTTI

OR1E3

121

Q8WZA6
YLPNAHLECHYTLTP

TAX1BP1

26

Q86VP1
YLQYPSLIPHHQCSQ

APEH

316

P13798
TVYSLCHPCHIHYDL

CHST11

261

Q9NPF2
PVYHLCQPCAVHYDF

CHST14

281

Q8NCH0
KYHPCYPGVHCINLS

THBS4

331

P35443
ALVVHPCPYCSHKTY

ZNF516

756

Q92618
QAYLPNCHRTYSCIH

YPEL1

11

O60688
ALYCVCHKSTYSPLP

MRPL42

26

Q9Y6G3
CTYIVYQCSRPAPLH

RALGAPB

811

Q86X10
QAYLPSCHRTYSCIH

YPEL2

11

Q96QA6