Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR51A4 OR51A2 OR5D16 NPBWR1 NPBWR2 CYSLTR2 OR2AK2 OR10A7 OR5M9 OR2M7 OR8U1 GALR1 GPR50 OR1B1 OR10P1 OR11H4 OR4E2 OR2C3 OR5K4 OR2F1 OR5AR1 ADGRA2 OR6X1 OR8U9 OR51E2 FZD7 OR52B4 TAS2R16 OR5J2 OR5AC2 CELSR2 OR51M1 OR7D2 OR51I2 GPR75 OR52N4 RRH OR51V1 OR8D4 OR4K3 GPR119 CXCR1	2.95e-23	884	144	42	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR51A4 OR51A2 OR5D16 CHRNA6 NPBWR1 NPBWR2 CYSLTR2 OR2AK2 OR10A7 OR5M9 OR2M7 OR8U1 GALR1 GPR50 OR1B1 OR10P1 OR11H4 OR4E2 HTR3E OR2C3 OR5K4 OR2F1 OR5AR1 ADGRA2 CHRNA2 CHRNA3 OR6X1 OR8U9 OR51E2 FZD7 OR52B4 TAS2R16 OR5J2 OR5AC2 CELSR2 PTPRR PLXNC1 OR51M1 OR7D2 OR51I2 GPR75 OR52N4 RRH OR51V1 OR8D4 OR4K3 GPR119 CXCR1	2.70e-21	1353	144	48	GO:0004888
GeneOntologyMolecularFunction	olfactory receptor activity	OR51A4 OR51A2 OR5D16 OR2AK2 OR10A7 OR5M9 OR2M7 OR8U1 OR1B1 OR10P1 OR11H4 OR4E2 OR2C3 OR5K4 OR2F1 OR5AR1 OR6X1 OR8U9 OR51E2 OR52B4 OR5J2 OR5AC2 OR51M1 OR7D2 OR51I2 OR52N4 OR51V1 OR8D4 OR4K3	4.24e-20	431	144	29	GO:0004984
GeneOntologyMolecularFunction	odorant binding	OR5D16 OR5M9 OR8U1 OR4E2 OR5K4 OR5AR1 OR8U9 OR5J2 OR5AC2 OR8D4	2.83e-08	127	144	10	GO:0005549
GeneOntologyMolecularFunction	monoatomic ion channel activity	CACNA1C TPTE CHRNA6 KCNH7 TPCN2 TMC2 HTR3E TMEM175 ANO5 PKDREJ CHRNA2 CHRNA3 KCND3 KCNH2 SCN5A ANO7 PACC1	3.70e-08	459	144	17	GO:0005216
GeneOntologyMolecularFunction	channel activity	CACNA1C TPTE CHRNA6 KCNH7 TPCN2 TMC2 HTR3E TMEM175 ANO5 PKDREJ CHRNA2 CHRNA3 KCND3 KCNH2 SCN5A ANO7 PACC1	2.52e-07	525	144	17	GO:0015267
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	CACNA1C TPTE CHRNA6 ATP13A4 KCNH7 TPCN2 ATP7A TMC2 HTR3E TMEM175 ANO5 PKDREJ CHRNA2 CHRNA3 KCND3 KCNH2 UCP1 SCN5A ANO7 PACC1 ATP13A3	2.58e-07	793	144	21	GO:0015075
GeneOntologyMolecularFunction	passive transmembrane transporter activity	CACNA1C TPTE CHRNA6 KCNH7 TPCN2 TMC2 HTR3E TMEM175 ANO5 PKDREJ CHRNA2 CHRNA3 KCND3 KCNH2 SCN5A ANO7 PACC1	2.59e-07	526	144	17	GO:0022803
GeneOntologyMolecularFunction	gated channel activity	CACNA1C CHRNA6 KCNH7 TPCN2 TMC2 HTR3E ANO5 CHRNA2 CHRNA3 KCND3 KCNH2 ANO7 PACC1	9.36e-07	334	144	13	GO:0022836
GeneOntologyMolecularFunction	transmembrane transporter activity	CACNA1C TPTE CHRNA6 ATP13A4 KCNH7 TPCN2 ATP7A TMC2 FLVCR1 HTR3E TMEM175 SLC19A2 ANO5 PKDREJ CHRNA2 CHRNA3 KCND3 KCNH2 UCP1 SCN5A ANO7 PACC1 ATP13A3 SLC51A SLC22A20P	1.10e-06	1180	144	25	GO:0022857
GeneOntologyMolecularFunction	monoatomic cation channel activity	CACNA1C CHRNA6 KCNH7 TPCN2 TMC2 HTR3E TMEM175 PKDREJ CHRNA2 CHRNA3 KCND3 KCNH2 SCN5A	1.26e-06	343	144	13	GO:0005261
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	CHRNA6 KCNH7 TPCN2 HTR3E ANO5 CHRNA2 CHRNA3 KCNH2 ANO7 PACC1	1.41e-06	193	144	10	GO:0015276
GeneOntologyMolecularFunction	ligand-gated channel activity	CHRNA6 KCNH7 TPCN2 HTR3E ANO5 CHRNA2 CHRNA3 KCNH2 ANO7 PACC1	1.70e-06	197	144	10	GO:0022834
GeneOntologyMolecularFunction	transporter activity	CACNA1C TPTE CHRNA6 ATP13A4 KCNH7 TPCN2 ATP7A TMC2 FLVCR1 HTR3E TMEM175 SLC19A2 ANO5 PKDREJ CHRNA2 CHRNA3 KCND3 KCNH2 UCP1 SCN5A ANO7 PACC1 ATP13A3 SLC51A SLC22A20P	5.30e-06	1289	144	25	GO:0005215
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	CACNA1C CHRNA6 ATP13A4 KCNH7 TPCN2 ATP7A TMC2 HTR3E TMEM175 PKDREJ CHRNA2 CHRNA3 KCND3 KCNH2 UCP1 SCN5A ATP13A3	6.17e-06	664	144	17	GO:0008324
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	CHRNA6 KCNH7 TPCN2 HTR3E CHRNA2 CHRNA3 KCNH2	7.08e-05	140	144	7	GO:0099094
GeneOntologyMolecularFunction	acetylcholine-gated monoatomic cation-selective channel activity	CHRNA6 CHRNA2 CHRNA3	2.32e-04	17	144	3	GO:0022848
GeneOntologyMolecularFunction	excitatory extracellular ligand-gated monoatomic ion channel activity	CHRNA6 HTR3E CHRNA2 CHRNA3	2.57e-04	43	144	4	GO:0005231
GeneOntologyMolecularFunction	superoxide-generating NADPH oxidase activity	NOX4 NOX1	3.07e-04	4	144	2	GO:0106292
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	CACNA1C ATP13A4 KCNH7 TPCN2 ATP7A TMC2 TMEM175 ANO5 PKDREJ KCND3 KCNH2 UCP1 SCN5A ANO7 PACC1	3.87e-04	758	144	15	GO:0015318
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	CACNA1C ATP13A4 KCNH7 TPCN2 ATP7A TMC2 TMEM175 PKDREJ KCND3 KCNH2 SCN5A	5.64e-04	465	144	11	GO:0046873
GeneOntologyMolecularFunction	acetylcholine receptor activity	CHRNA6 CHRNA2 CHRNA3	5.85e-04	23	144	3	GO:0015464
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	CHRNA6 HTR3E CHRNA2 CHRNA3	7.62e-04	57	144	4	GO:1904315
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	CACNA1C KCNH7 TPCN2 TMC2 KCND3 KCNH2	8.29e-04	152	144	6	GO:0022843
GeneOntologyMolecularFunction	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	CHRNA6 HTR3E CHRNA2 CHRNA3	9.25e-04	60	144	4	GO:0099529
GeneOntologyMolecularFunction	G protein-coupled opioid receptor activity	NPBWR1 NPBWR2	1.06e-03	7	144	2	GO:0004985
GeneOntologyMolecularFunction	transmitter-gated channel activity	CHRNA6 HTR3E CHRNA2 CHRNA3	1.25e-03	65	144	4	GO:0022835
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity	CHRNA6 HTR3E CHRNA2 CHRNA3	1.25e-03	65	144	4	GO:0022824
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	CACNA1C ATP13A4 KCNH7 TPCN2 ATP7A TMC2 TMEM175 PKDREJ KCND3 KCNH2 UCP1 SCN5A	1.98e-03	627	144	12	GO:0022890
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	CACNA1C KCNH7 TPCN2 TMC2 KCND3 KCNH2	2.08e-03	182	144	6	GO:0005244
GeneOntologyMolecularFunction	postsynaptic neurotransmitter receptor activity	CHRNA6 HTR3E CHRNA2 CHRNA3	2.12e-03	75	144	4	GO:0098960
GeneOntologyMolecularFunction	voltage-gated channel activity	CACNA1C KCNH7 TPCN2 TMC2 KCND3 KCNH2	2.20e-03	184	144	6	GO:0022832
GeneOntologyMolecularFunction	P-type transmembrane transporter activity	ATP13A4 ATP7A ATP13A3	2.20e-03	36	144	3	GO:0140358
GeneOntologyMolecularFunction	P-type ion transporter activity	ATP13A4 ATP7A ATP13A3	2.20e-03	36	144	3	GO:0015662
GeneOntologyMolecularFunction	extracellular ligand-gated monoatomic ion channel activity	CHRNA6 HTR3E CHRNA2 CHRNA3	2.34e-03	77	144	4	GO:0005230
GeneOntologyMolecularFunction	neuropeptide binding	NPBWR1 NPBWR2 GALR1	2.38e-03	37	144	3	GO:0042923
GeneOntologyMolecularFunction	polyamine transmembrane transporter activity	ATP13A4 ATP13A3	2.72e-03	11	144	2	GO:0015203
GeneOntologyMolecularFunction	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	KCND3 KCNH2	3.25e-03	12	144	2	GO:1902282
GeneOntologyMolecularFunction	NAD(P)H oxidase H2O2-forming activity	NOX4 NOX1	3.25e-03	12	144	2	GO:0016174
GeneOntologyMolecularFunction	superoxide-generating NAD(P)H oxidase activity	NOX4 NOX1	3.25e-03	12	144	2	GO:0016175
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACNA1C TPCN2 TMC2	4.44e-03	46	144	3	GO:0005245
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR51A4 OR51A2 OR5D16 OR2AK2 OR10A7 OR5M9 OR2M7 OR8U1 OR1B1 OR10P1 OR11H4 OR4E2 OR2C3 OR5K4 OR2F1 OR5AR1 OR6X1 OR8U9 OR51E2 OR52B4 OR5J2 OR5AC2 OR51M1 OR7D2 OR51I2 OR52N4 OR51V1 OR8D4 OR4K3	1.26e-20	432	142	29	GO:0050911
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR51A4 OR51A2 OR5D16 OR2AK2 OR10A7 OR5M9 OR2M7 OR8U1 OR1B1 OR10P1 OR11H4 OR4E2 OR2C3 OR5K4 OR2F1 OR5AR1 OR6X1 OR8U9 OR51E2 OR52B4 TAS2R16 OR5J2 OR5AC2 OR51M1 OR7D2 OR51I2 OR52N4 OR51V1 OR8D4 OR4K3	2.57e-20	485	142	30	GO:0050907
GeneOntologyBiologicalProcess	sensory perception of smell	OR51A4 OR51A2 OR5D16 OR2AK2 OR10A7 OR5M9 OR2M7 OR8U1 OR1B1 OR10P1 OR11H4 OR4E2 OR2C3 OR5K4 OR2F1 OR5AR1 OR6X1 OR8U9 OR51E2 OR52B4 OR5J2 OR5AC2 OR51M1 OR7D2 OR51I2 OR52N4 OR51V1 OR8D4 OR4K3	9.53e-20	465	142	29	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR51A4 OR51A2 OR5D16 OR2AK2 OR10A7 OR5M9 OR2M7 OR8U1 OR1B1 OR10P1 OR11H4 OR4E2 OR2C3 OR5K4 OR2F1 OR5AR1 OR6X1 OR8U9 OR51E2 OR52B4 TAS2R16 OR5J2 OR5AC2 OR51M1 OR7D2 OR51I2 OR52N4 OR51V1 OR8D4 OR4K3	2.28e-19	524	142	30	GO:0009593
GeneOntologyBiologicalProcess	detection of stimulus	OR51A4 OR51A2 OR5D16 OR2AK2 OR10A7 OR5M9 OR2M7 OR8U1 TMC2 OR1B1 OR10P1 OR11H4 OR4E2 OR2C3 OR5K4 OR2F1 OR5AR1 PKDREJ OR6X1 OR8U9 OR51E2 OR52B4 JUP TAS2R16 OR5J2 OR5AC2 OR51M1 OR7D2 OR51I2 OR52N4 RRH OR51V1 OR8D4 OR4K3	2.87e-19	722	142	34	GO:0051606
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR51A4 OR51A2 OR5D16 OR2AK2 OR10A7 OR5M9 OR2M7 OR8U1 TMC2 OR1B1 OR10P1 OR11H4 OR4E2 OR2C3 OR5K4 OR2F1 OR5AR1 OR6X1 OR8U9 OR51E2 OR52B4 TAS2R16 OR5J2 OR5AC2 OR51M1 OR7D2 OR51I2 OR52N4 OR51V1 OR8D4 OR4K3	4.21e-19	582	142	31	GO:0050906
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR51A4 OR51A2 OR5D16 OR2AK2 OR10A7 OR5M9 OR2M7 OR8U1 OR1B1 OR10P1 OR11H4 OR4E2 OR2C3 OR5K4 OR2F1 OR5AR1 OR6X1 OR8U9 OR51E2 OR52B4 TAS2R16 OR5J2 OR5AC2 OR51M1 OR7D2 OR51I2 OR52N4 OR51V1 OR8D4 OR4K3	7.56e-19	547	142	30	GO:0007606
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR51A4 OR51A2 OR5D16 NPBWR1 NPBWR2 CYSLTR2 OR2AK2 OR10A7 OR5M9 OR2M7 OR8U1 GALR1 GPR50 OR1B1 OR10P1 OR11H4 OR4E2 OR2C3 OR5K4 OR2F1 OR5AR1 ADGRA2 OR6X1 OR8U9 OR51E2 FZD7 OR52B4 TAS2R16 OR5J2 OR5AC2 CELSR2 OR51M1 ATRNL1 OR7D2 OR51I2 GPR75 OR52N4 RRH ARRDC3 OR51V1 OR8D4 OR4K3 GPR119 CXCR1	2.86e-18	1395	142	44	GO:0007186
GeneOntologyBiologicalProcess	sensory perception	OR51A4 OR51A2 OR5D16 OR2AK2 OR10A7 OR5M9 OR2M7 OR8U1 TMC2 OR1B1 OR10P1 OR11H4 OR4E2 OR2C3 OR5K4 OR2F1 OR5AR1 OR6X1 OR8U9 OR51E2 OR52B4 TAS2R16 OR5J2 OR5AC2 OR51M1 OR7D2 OR51I2 OR52N4 RRH OR51V1 OR8D4 OR4K3 ANKFN1	2.35e-13	1072	142	33	GO:0007600
GeneOntologyBiologicalProcess	ventricular cardiac muscle cell action potential	CACNA1C JUP KCND3 KCNH2 SCN5A	5.26e-06	37	142	5	GO:0086005
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	CACNA1C TPTE CHRNA6 ATP13A4 KCNH7 TPCN2 ATP7A TMC2 HTR3E TMEM175 ANO5 PKDREJ CHRNA2 CHRNA3 KCND3 KCNH2 UCP1 SCN5A ANO7 PACC1 ATP13A3 STEAP1B	7.77e-06	1115	142	22	GO:0034220
GeneOntologyBiologicalProcess	regulation of heart rate by cardiac conduction	CACNA1C JUP KCND3 KCNH2 SCN5A	8.85e-06	41	142	5	GO:0086091
GeneOntologyBiologicalProcess	monoatomic ion transport	CACNA1C TPTE CHRNA6 ATP13A4 KCNH7 TPCN2 ATP7A TMC2 FLVCR1 HTR3E TMEM175 ANO5 PKDREJ CHRNA2 CHRNA3 KCND3 KCNH2 UCP1 SCN5A ANO7 PACC1 ATP13A3 STEAP1B SLC22A20P	2.18e-05	1374	142	24	GO:0006811
GeneOntologyBiologicalProcess	cardiac muscle cell action potential involved in contraction	CACNA1C JUP KCND3 KCNH2 SCN5A	6.80e-05	62	142	5	GO:0086002
GeneOntologyBiologicalProcess	membrane depolarization during atrial cardiac muscle cell action potential	CACNA1C SCN5A	1.41e-04	3	142	2	GO:0098912
GeneOntologyBiologicalProcess	membrane depolarization	CACNA1C CHRNA6 CHRNA2 CHRNA3 KCNH2 SCN5A	1.92e-04	121	142	6	GO:0051899
GeneOntologyBiologicalProcess	cardiac muscle cell action potential	CACNA1C JUP KCND3 KCNH2 SCN5A	3.38e-04	87	142	5	GO:0086001
GeneOntologyCellularComponent	monoatomic ion channel complex	CACNA1C CHRNA6 KCNH7 TPCN2 HTR3E CHRNA2 CHRNA3 KCND3 KCNH2 SCN5A PACC1	6.39e-05	378	144	11	GO:0034702
GeneOntologyCellularComponent	acetylcholine-gated channel complex	CHRNA6 CHRNA2 CHRNA3	2.42e-04	18	144	3	GO:0005892
HumanPheno	Abnormal autonomic nervous system physiology	CACNA1C ATP7A VPS13C CHRNA3 MMEL1 KCNH2 SCN5A DEPDC5	5.61e-06	130	40	8	HP:0012332
HumanPheno	Abnormality of the autonomic nervous system	RAD51 CACNA1C ATP7A VPS13C CHRNA3 FANCA MMEL1 KCNH2 SCN5A KATNIP DEPDC5	4.67e-05	346	40	11	HP:0002270
HumanPheno	Paroxysmal ventricular tachycardia	CACNA1C JUP KCND3 SCN5A	5.02e-05	27	40	4	HP:0004751
Domain	GPCR_Rhodpsn_7TM	OR51A4 OR51A2 OR5D16 NPBWR1 NPBWR2 CYSLTR2 OR2AK2 OR10A7 OR5M9 OR2M7 OR8U1 GALR1 GPR50 OR1B1 OR10P1 OR11H4 OR4E2 OR2C3 OR5K4 OR2F1 OR5AR1 OR6X1 OR8U9 OR51E2 OR52B4 OR5J2 OR5AC2 OR51M1 OR7D2 OR51I2 GPR75 OR52N4 RRH OR51V1 OR8D4 GPR119 CXCR1	8.71e-22	670	143	37	IPR017452
Domain	7tm_1	OR51A4 OR51A2 OR5D16 NPBWR1 NPBWR2 CYSLTR2 OR2AK2 OR10A7 OR5M9 OR2M7 OR8U1 GALR1 GPR50 OR1B1 OR10P1 OR11H4 OR4E2 OR2C3 OR5K4 OR2F1 OR5AR1 OR6X1 OR8U9 OR51E2 OR52B4 OR5J2 OR5AC2 OR51M1 OR7D2 OR51I2 GPR75 OR52N4 RRH OR51V1 OR8D4 GPR119 CXCR1	1.24e-21	677	143	37	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR51A4 OR51A2 OR5D16 NPBWR1 NPBWR2 CYSLTR2 OR2AK2 OR10A7 OR5M9 OR2M7 OR8U1 GALR1 GPR50 OR1B1 OR10P1 OR11H4 OR4E2 OR2C3 OR5K4 OR2F1 OR5AR1 OR6X1 OR8U9 OR51E2 OR52B4 OR5J2 OR5AC2 OR51M1 OR7D2 OR51I2 GPR75 OR52N4 RRH OR51V1 OR8D4 GPR119 CXCR1	1.85e-21	685	143	37	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR51A4 OR51A2 OR5D16 NPBWR1 NPBWR2 CYSLTR2 OR2AK2 OR10A7 OR5M9 OR2M7 OR8U1 GALR1 GPR50 OR1B1 OR10P1 OR11H4 OR4E2 OR2C3 OR5K4 OR2F1 OR5AR1 OR6X1 OR8U9 OR51E2 OR52B4 OR5J2 OR5AC2 OR51M1 OR7D2 OR51I2 GPR75 OR52N4 RRH OR51V1 OR8D4 GPR119 CXCR1	2.50e-21	691	143	37	PS50262
Domain	GPCR_Rhodpsn	OR51A4 OR51A2 OR5D16 NPBWR1 NPBWR2 CYSLTR2 OR2AK2 OR10A7 OR5M9 OR2M7 OR8U1 GALR1 GPR50 OR1B1 OR10P1 OR11H4 OR4E2 OR2C3 OR5K4 OR2F1 OR5AR1 OR6X1 OR8U9 OR51E2 OR52B4 OR5J2 OR5AC2 OR51M1 OR7D2 OR51I2 GPR75 OR52N4 RRH OR51V1 OR8D4 GPR119 CXCR1	2.62e-21	692	143	37	IPR000276
Domain	Olfact_rcpt	OR51A4 OR51A2 OR5D16 OR2AK2 OR10A7 OR5M9 OR2M7 OR8U1 OR1B1 OR10P1 OR11H4 OR4E2 OR2C3 OR5K4 OR2F1 OR5AR1 OR6X1 OR8U9 OR51E2 OR52B4 OR5J2 OR5AC2 OR51M1 OR7D2 OR51I2 OR52N4 OR51V1 OR8D4	2.04e-19	393	143	28	IPR000725
Domain	7TM_GPCR_Srsx	OR51A4 OR51A2 NPBWR2 GALR1 GPR50 OR51I2 RRH	2.47e-05	112	143	7	SM01381
Domain	-	CHRNA6 HTR3E CHRNA2 CHRNA3	2.61e-05	23	143	4	1.20.120.370
Domain	Acetylcholine_rcpt_TM	CHRNA6 HTR3E CHRNA2 CHRNA3	2.61e-05	23	143	4	IPR027361
Domain	Ion_trans_dom	CACNA1C TPTE KCNH7 TPCN2 KCND3 KCNH2 SCN5A	2.77e-05	114	143	7	IPR005821
Domain	Ion_trans	CACNA1C TPTE KCNH7 TPCN2 KCND3 KCNH2 SCN5A	2.77e-05	114	143	7	PF00520
Domain	Neuropept_B/W_rcpt	NPBWR1 NPBWR2	5.82e-05	2	143	2	IPR009150
Domain	Ferric_reduct	NOX4 NOX1 STEAP1B	9.19e-05	12	143	3	PF01794
Domain	Fe3_Rdtase_TM_dom	NOX4 NOX1 STEAP1B	9.19e-05	12	143	3	IPR013130
Domain	K_chnl_volt-dep_ERG	KCNH7 KCNH2	1.74e-04	3	143	2	IPR003967
Domain	Nicotinic_acetylcholine_rcpt	CHRNA6 CHRNA2 CHRNA3	2.29e-04	16	143	3	IPR002394
Domain	Cyt_b245_heavy_chain	NOX4 NOX1	3.46e-04	4	143	2	IPR000778
Domain	P5-ATPase	ATP13A4 ATP13A3	3.46e-04	4	143	2	PF12409
Domain	Neurotransmitter_ion_chnl_CS	CHRNA6 HTR3E CHRNA2 CHRNA3	3.85e-04	45	143	4	IPR018000
Domain	Neur_chan_memb	CHRNA6 HTR3E CHRNA2 CHRNA3	4.19e-04	46	143	4	PF02932
Domain	Neurotrans-gated_channel_TM	CHRNA6 HTR3E CHRNA2 CHRNA3	4.55e-04	47	143	4	IPR006029
Domain	-	CHRNA6 HTR3E CHRNA2 CHRNA3	4.55e-04	47	143	4	2.70.170.10
Domain	Neur_chan_LBD	CHRNA6 HTR3E CHRNA2 CHRNA3	4.55e-04	47	143	4	PF02931
Domain	NEUROTR_ION_CHANNEL	CHRNA6 HTR3E CHRNA2 CHRNA3	4.55e-04	47	143	4	PS00236
Domain	Neur_channel	CHRNA6 HTR3E CHRNA2 CHRNA3	4.55e-04	47	143	4	IPR006201
Domain	Neur_chan_lig-bd	CHRNA6 HTR3E CHRNA2 CHRNA3	4.55e-04	47	143	4	IPR006202
Domain	P-type_TPase_V	ATP13A4 ATP13A3	5.73e-04	5	143	2	IPR006544
Domain	Channel_four-helix_dom	CACNA1C TPCN2 KCND3 SCN5A	9.50e-04	57	143	4	IPR027359
Domain	-	CACNA1C TPCN2 KCND3 SCN5A	9.50e-04	57	143	4	1.20.120.350
Domain	Anoct_dimer	ANO5 ANO7	1.19e-03	7	143	2	PF16178
Domain	Anoct_dimer	ANO5 ANO7	1.19e-03	7	143	2	IPR032394
Domain	NAD_binding_6	NOX4 NOX1	1.19e-03	7	143	2	PF08030
Domain	FAD_binding_8	NOX4 NOX1	1.19e-03	7	143	2	PF08022
Domain	FAD-bd_8	NOX4 NOX1	1.19e-03	7	143	2	IPR013112
Domain	Fe_red_NAD-bd_6	NOX4 NOX1	1.19e-03	7	143	2	IPR013121
Domain	-	ATP13A4 ATP7A ATP13A3	1.85e-03	32	143	3	3.40.1110.10
Domain	-	ATP13A4 ATP7A ATP13A3	1.85e-03	32	143	3	2.70.150.10
Domain	GPS	PKDREJ ADGRA2 CELSR2	2.21e-03	34	143	3	SM00303
Domain	ATPase_P-typ_cyto_domN	ATP13A4 ATP7A ATP13A3	2.40e-03	35	143	3	IPR023299
Domain	Anoctamin	ANO5 ANO7	2.52e-03	10	143	2	PF04547
Domain	Anoctamin	ANO5 ANO7	2.52e-03	10	143	2	IPR007632
Domain	PAS_9	KCNH7 KCNH2	2.52e-03	10	143	2	PF13426
Domain	ATPase_P-typ_P_site	ATP13A4 ATP7A ATP13A3	2.61e-03	36	143	3	IPR018303
Domain	P_typ_ATPase	ATP13A4 ATP7A ATP13A3	2.61e-03	36	143	3	IPR001757
Domain	ATPASE_E1_E2	ATP13A4 ATP7A ATP13A3	2.61e-03	36	143	3	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP13A4 ATP7A ATP13A3	2.82e-03	37	143	3	IPR008250
Domain	GPS	PKDREJ ADGRA2 CELSR2	2.82e-03	37	143	3	IPR000203
Domain	E1-E2_ATPase	ATP13A4 ATP7A ATP13A3	2.82e-03	37	143	3	PF00122
Domain	K_chnl_volt-dep_EAG/ELK/ERG	KCNH7 KCNH2	4.99e-03	14	143	2	IPR003938
Domain	HEAT	ECPAS JUP MROH1	5.91e-03	48	143	3	PF02985
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR51A4 OR51A2 OR5D16 OR2AK2 OR10A7 OR5M9 OR2M7 OR8U1 OR1B1 OR10P1 OR11H4 OR4E2 OR2C3 OR5K4 OR2F1 OR5AR1 OR6X1 OR8U9 OR51E2 OR5J2 OR5AC2 OR51M1 OR7D2 OR51I2 OR52N4 OR51V1 OR8D4 OR4K3	1.26e-18	417	112	28	M4072
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR51A4 OR51A2 OR5D16 OR2AK2 OR10A7 OR5M9 OR2M7 OR8U1 OR1B1 OR10P1 OR11H4 OR4E2 OR2C3 OR2F1 OR5AR1 OR6X1 OR51E2 OR52B4 OR5J2 OR5AC2 OR51M1 OR7D2 OR51I2 OR52N4 OR51V1 OR8D4	2.92e-17	389	112	26	M14091
Pathway	REACTOME_SENSORY_PERCEPTION	OR51A4 OR51A2 OR5D16 OR2AK2 OR10A7 OR5M9 OR2M7 OR8U1 TMC2 OR1B1 OR10P1 OR11H4 RBP1 OR4E2 OR2C3 OR5K4 OR2F1 OR5AR1 OR6X1 OR8U9 OR51E2 TAS2R16 OR5J2 OR5AC2 OR51M1 OR7D2 OR51I2 OR52N4 OR51V1 OR8D4 OR4K3	1.24e-16	636	112	31	M41834
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA6 CHRNA2 CHRNA3	3.96e-05	9	112	3	M27597
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA6 CHRNA2 CHRNA3	3.96e-05	9	112	3	MM15313
Pathway	WP_GPCRS_NONODORANT	NPBWR1 CYSLTR2 GALR1 GPR50 FZD7 TAS2R16 CELSR2 RRH GPR119 CXCR1	5.04e-05	266	112	10	MM15843
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA6 CHRNA2 CHRNA3	7.69e-05	11	112	3	M883
Pathway	REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA6 CHRNA2 CHRNA3	1.02e-04	12	112	3	M48008
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA6 CHRNA2 CHRNA3	1.02e-04	12	112	3	MM15312
Pathway	REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS	CHRNA6 CHRNA2 CHRNA3	1.67e-04	14	112	3	M757
Pathway	REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS	CHRNA6 CHRNA2 CHRNA3	2.07e-04	15	112	3	MM14704
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	NPBWR1 NPBWR2 CYSLTR2 GALR1 GPR50 OR2F1 GPR75 RRH CXCR1	2.26e-04	260	112	9	M39397
Pathway	WP_GPCRS_OTHER	OR2F1 OR5AC2 CELSR2 ALG6 CXCR1	8.63e-04	93	112	5	M39629
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR5D16 OR2AK2 OR5M9 OR2M7 OR8U1 OR1B1 OR10P1 OR11H4 OR4E2 OR5K4 OR2F1 OR5AR1 OR6X1 OR51E2 OR52B4 OR5J2 OR51M1 OR51I2 OR52N4 OR51V1 OR8D4	1.01e-18	340	144	21	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR5D16 OR2AK2 OR5M9 OR2M7 OR8U1 OR1B1 OR10P1 OR11H4 OR4E2 OR5K4 OR2F1 OR5AR1 OR6X1 OR51E2 OR52B4 OR5J2 OR51M1 OR51I2 OR52N4 OR51V1 OR8D4	1.01e-18	340	144	21	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR5D16 OR2AK2 OR5M9 OR2M7 OR8U1 OR1B1 OR10P1 OR11H4 OR4E2 OR5K4 OR2F1 OR5AR1 OR6X1 OR51E2 OR52B4 OR5J2 OR51M1 OR51I2 OR52N4 OR51V1 OR8D4	1.21e-18	343	144	21	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR5D16 OR2AK2 OR5M9 OR2M7 OR8U1 OR1B1 OR10P1 OR11H4 OR4E2 OR5K4 OR2F1 OR5AR1 OR6X1 OR51E2 OR52B4 OR5J2 OR51M1 OR51I2 OR52N4 OR51V1 OR8D4	1.44e-18	346	144	21	14611657
Pubmed	The human olfactory receptor gene family.	OR5D16 OR2AK2 OR10A7 OR5M9 OR2M7 OR1B1 OR10P1 OR11H4 OR4E2 OR2C3 OR2F1 OR5AR1 OR6X1 OR51E2 OR52B4 OR5J2 OR51M1 OR7D2 OR51I2 OR52N4 OR51V1 OR8D4 OR4K3	7.55e-17	541	144	23	14983052
Pubmed	Voltage gated ion channels blockade is the underlying mechanism of BIMU8 induced cardiotoxicity.	CACNA1C KCNH2 SCN5A	6.95e-08	3	144	3	28552773
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR5D16 OR10A7 OR5M9 OR10P1 OR4E2 OR2C3 OR2F1 OR7D2 OR4K3	3.60e-07	219	144	9	12213199
Pubmed	Brugada Syndrome	CACNA1C KCND3 KCNH2 SCN5A	2.81e-06	24	144	4	20301690
Pubmed	Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.	CHRNA6 CHRNA2 CHRNA3	5.73e-06	9	144	3	8906617
Pubmed	Sources of energy for gating by neurotransmitters in acetylcholine receptor channels.	CHRNA6 CHRNA2 CHRNA3	5.73e-06	9	144	3	22647603
Pubmed	Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerström test for nicotine dependence.	CHRNA6 CHRNA2 CHRNA3	8.17e-06	10	144	3	20736995
Pubmed	A novel conditional mouse model for Nkx2-5 reveals transcriptional regulation of cardiac ion channels.	CACNA1C KCNH2 SCN5A	8.17e-06	10	144	3	26897459
Pubmed	Aberrant Expression of a Non-muscle RBFOX2 Isoform Triggers Cardiac Conduction Defects in Myotonic Dystrophy.	CACNA1C KCND3 SCN5A	8.17e-06	10	144	3	32109384
Pubmed	Differential expression of nicotinic acetylcholine receptor subunits in fetal and neonatal mouse thymus.	CHRNA6 CHRNA2 CHRNA3	1.12e-05	11	144	3	12225896
Pubmed	LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation.	CACNA1C KCND3 KCNH2 SCN5A	1.19e-05	34	144	4	26378152
Pubmed	A probabilistic classifier for olfactory receptor pseudogenes.	OR1B1 OR2F1 OR5AR1 OR52B4	1.34e-05	35	144	4	16939646
Pubmed	Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans.	CHRNA6 CHRNA2 CHRNA3	1.49e-05	12	144	3	20584212
Pubmed	Utility of frozen cell lines in medium throughput electrophysiology screening of hERG and NaV1.5 blockade.	KCNH2 SCN5A	1.70e-05	2	144	2	21996251
Pubmed	Nrf2 facilitates repair of radiation induced DNA damage through homologous recombination repair pathway in a ROS independent manner in cancer cells.	RAD51 NFE2L2	1.70e-05	2	144	2	26133502
Pubmed	Co-expression of calcium and hERG potassium channels reduces the incidence of proarrhythmic events.	CACNA1C KCNH2	1.70e-05	2	144	2	33002116
Pubmed	NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).	NOX4 NOX1	1.70e-05	2	144	2	20715105
Pubmed	Nrf2 regulates hyperoxia-induced Nox4 expression in human lung endothelium: identification of functional antioxidant response elements on the Nox4 promoter.	NOX4 NFE2L2	1.70e-05	2	144	2	21443946
Pubmed	Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of Type 2 diabetes.	NOX4 NOX1	1.70e-05	2	144	2	22920224
Pubmed	Association of Arrhythmia-Related Genetic Variants With Phenotypes Documented in Electronic Medical Records.	KCNH2 SCN5A	1.70e-05	2	144	2	26746457
Pubmed	Gastrointestinal symptoms in families of patients with an SCN5A-encoded cardiac channelopathy: evidence of an intestinal channelopathy.	KCNH2 SCN5A	1.70e-05	2	144	2	16771953
Pubmed	NOX1 and NOX4 are required for the differentiation of mouse F9 cells into extraembryonic endoderm.	NOX4 NOX1	1.70e-05	2	144	2	28152080
Pubmed	Distinct subcellular localizations of Nox1 and Nox4 in vascular smooth muscle cells.	NOX4 NOX1	1.70e-05	2	144	2	14670934
Pubmed	Wnt is necessary for mesenchymal to epithelial transition in colorectal cancer cells.	WNT2B FZD7	1.70e-05	2	144	2	28560804
Pubmed	Analysis of KCNH2 and CACNA1C schizophrenia risk genes on EEG functional network modulation during an auditory odd-ball task.	CACNA1C KCNH2	1.70e-05	2	144	2	30607529
Pubmed	Overexpression of the superoxide anion and NADPH oxidase isoforms 1 and 4 (NOX1 and NOX4) in allergic nasal mucosa.	NOX4 NOX1	1.70e-05	2	144	2	19671250
Pubmed	Coexistence of Andersen-Tawil Syndrome with Polymorphisms in hERG1 Gene (K897T) and SCN5A Gene (H558R) in One Family.	KCNH2 SCN5A	1.70e-05	2	144	2	26109178
Pubmed	Complex Brugada syndrome inheritance in a family harbouring compound SCN5A and CACNA1C mutations.	CACNA1C SCN5A	1.70e-05	2	144	2	25341504
Pubmed	Nicotinamide adenine dinucleotide phosphate oxidase-4-dependent upregulation of nuclear factor erythroid-derived 2-like 2 protects the heart during chronic pressure overload.	NOX4 NFE2L2	1.70e-05	2	144	2	25534702
Pubmed	Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics.	KCNH2 SCN5A	1.70e-05	2	144	2	23277474
Pubmed	Assignment of the cellular retinol-binding protein 1 gene (RBP1) and of the coatomer beta subunit gene (COPB2) to human chromosome band 3q23 by in situ hybridization.	RBP1 COPB2	1.70e-05	2	144	2	9858824
Pubmed	Identification of structural elements in Nox1 and Nox4 controlling localization and activity.	NOX4 NOX1	1.70e-05	2	144	2	19061439
Pubmed	Digenic heterozygous mutations of KCNH2 and SCN5A induced young and early-onset long QT syndrome and sinoatrial node dysfunction.	KCNH2 SCN5A	1.70e-05	2	144	2	34755423
Pubmed	NOX1 Promotes Mesothelial-Mesenchymal Transition through Modulation of Reactive Oxygen Species-mediated Signaling.	NOX4 NOX1	1.70e-05	2	144	2	33513310
Pubmed	Analysis of the arrhythmogenic substrate in human heart failure.	KCND3 SCN5A	1.70e-05	2	144	2	23036686
Pubmed	Significant associations of CHRNA2 and CHRNA6 with nicotine dependence in European American and African American populations.	CHRNA6 CHRNA2	1.70e-05	2	144	2	24253422
Pubmed	Analysis of CACNA1C and KCNH2 Risk Variants on Cardiac Autonomic Function in Patients with Schizophrenia.	CACNA1C KCNH2	1.70e-05	2	144	2	36421807
Pubmed	Cardiac channelopathies associated with infantile fatal ventricular arrhythmias: from the cradle to the bench.	KCNH2 SCN5A	1.70e-05	2	144	2	24112685
Pubmed	Transcriptional regulation of NADPH oxidase isoforms, Nox1 and Nox4, by nuclear factor-kappaB in human aortic smooth muscle cells.	NOX4 NOX1	1.70e-05	2	144	2	20457132
Pubmed	NADPH Oxidase 4 (Nox4) Suppresses Mitochondrial Biogenesis and Bioenergetics in Lung Fibroblasts via a Nuclear Factor Erythroid-derived 2-like 2 (Nrf2)-dependent Pathway.	NOX4 NFE2L2	1.70e-05	2	144	2	28049732
Pubmed	Two long QT syndrome loci map to chromosomes 3 and 7 with evidence for further heterogeneity.	KCNH2 SCN5A	1.70e-05	2	144	2	7842012
Pubmed	ROS-generating oxidases Nox1 and Nox4 contribute to oncogenic Ras-induced premature senescence.	NOX4 NOX1	1.70e-05	2	144	2	23216904
Pubmed	Deficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice through Inhibition of Hepatic Stellate Cell Activation.	NOX4 NOX1	1.70e-05	2	144	2	26222337
Pubmed	Ether-à-go-go-related gene K+ channels contribute to threshold excitability of mouse auditory brainstem neurons.	KCNH7 KCNH2	1.70e-05	2	144	2	19359372
Pubmed	Long QT interval in Turner syndrome--a high prevalence of LQTS gene mutations.	KCNH2 SCN5A	1.70e-05	2	144	2	23936059
Pubmed	Brain adaptation to hypoxia and hyperoxia in mice.	NOX4 NFE2L2	1.70e-05	2	144	2	27835780
Pubmed	The cloning and chromosomal mapping of two novel human opioid-somatostatin-like receptor genes, GPR7 and GPR8, expressed in discrete areas of the brain.	NPBWR1 NPBWR2	1.70e-05	2	144	2	7590751
Pubmed	Reversal of persistent fibrosis in aging by targeting Nox4-Nrf2 redox imbalance.	NOX4 NFE2L2	1.70e-05	2	144	2	24718857
Pubmed	Nrf2 regulates the expression of NOX1 in TNF-α-induced A549 cells.	NOX1 NFE2L2	1.70e-05	2	144	2	36617822
Pubmed	Increased Energy Expenditure, Ucp1 Expression, and Resistance to Diet-induced Obesity in Mice Lacking Nuclear Factor-Erythroid-2-related Transcription Factor-2 (Nrf2).	NFE2L2 UCP1	1.70e-05	2	144	2	26841864
Pubmed	Epigenetic regulation of vascular NADPH oxidase expression and reactive oxygen species production by histone deacetylase-dependent mechanisms in experimental diabetes.	NOX4 NOX1	1.70e-05	2	144	2	29587244
Pubmed	Aging-related NOX4-Nrf2 redox imbalance increases susceptibility to cisplatin-induced acute kidney injury by regulating mitophagy.	NOX4 NFE2L2	1.70e-05	2	144	2	38104863
Pubmed	Nrf2 induces Ucp1 expression in adipocytes in response to β3-AR stimulation and enhances oxygen consumption in high-fat diet-fed obese mice.	NFE2L2 UCP1	1.70e-05	2	144	2	33691909
Pubmed	In utero onset of long QT syndrome with atrioventricular block and spontaneous or lidocaine-induced ventricular tachycardia: compound effects of hERG pore region mutation and SCN5A N-terminus variant.	KCNH2 SCN5A	1.70e-05	2	144	2	18848812
Pubmed	Personal receptor repertoires: olfaction as a model.	OR1B1 OR2F1 OR5AR1 OR52B4	1.86e-05	38	144	4	22908908
Pubmed	Functional suppression of Kcnq1 leads to early sodium channel remodelling and cardiac conduction system dysmorphogenesis.	KCND3 KCNH2 SCN5A	2.45e-05	14	144	3	23542581
Pubmed	Design and expression of human alpha7 nicotinic acetylcholine receptor extracellular domain mutants with enhanced solubility and ligand-binding properties.	CHRNA6 CHRNA2 CHRNA3	2.45e-05	14	144	3	19059502
Pubmed	Pacsin 2 is required for the maintenance of a normal cardiac function in the developing mouse heart.	CACNA1C KCNH2 SCN5A	2.45e-05	14	144	3	29107716
Pubmed	Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.	OR51M1 OR51I2 OR51V1	3.05e-05	15	144	3	11121057
Pubmed	Analysis of nicotinic acetylcholine receptor subunits in the cochlea of the mouse.	CHRNA6 CHRNA2 CHRNA3	3.05e-05	15	144	3	8838678
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	TLCD1 NPEPPS SLC19A2 MROH1 CELSR2 XPO5 NFE2L2 MACF1 PACC1 ATP13A3 UNC93B1 WDFY3 STEAP1B FUT8 ALG6	3.66e-05	1061	144	15	33845483
Pubmed	Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes.	CHRNA6 CHRNA2 CHRNA3	3.74e-05	16	144	3	19259974
Pubmed	NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion.	NOX4 NOX1	5.09e-05	3	144	2	22933115
Pubmed	Mitochondrial ROS driven by NOX4 upregulation promotes hepatocellular carcinoma cell survival after incomplete radiofrequency ablation by inducing of mitophagy via Nrf2/PINK1.	NOX4 NFE2L2	5.09e-05	3	144	2	36964576
Pubmed	Variant frequencies of KCNQ1, KCNH2, and SCN5A in a Chinese inherited arrhythmia cohort and other disease cohorts undergoing genetic testing.	KCNH2 SCN5A	5.09e-05	3	144	2	31696929
Pubmed	Co-treatment with hepatocyte growth factor and TGF-beta1 enhances migration of HaCaT cells through NADPH oxidase-dependent ROS generation.	NOX4 NOX1	5.09e-05	3	144	2	20177149
Pubmed	The response of the QT interval to the brief tachycardia provoked by standing: a bedside test for diagnosing long QT syndrome.	KCNH2 SCN5A	5.09e-05	3	144	2	20116193
Pubmed	Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias.	KCNH2 SCN5A	5.09e-05	3	144	2	11136691
Pubmed	Cardiac ion channel gene mutations in sudden infant death syndrome.	KCNH2 SCN5A	5.09e-05	3	144	2	18596570
Pubmed	Development of an improved and specific inhibitor of NADPH oxidase 2 to treat traumatic brain injury.	NOX4 NOX1	5.09e-05	3	144	2	36709665
Pubmed	The NADPH Oxidase Nox2 Mediates Vitamin D-Induced Vascular Regeneration in Male Mice.	NOX4 NOX1	5.09e-05	3	144	2	27399878
Pubmed	Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase.	NOX4 NOX1	5.09e-05	3	144	2	15322091
Pubmed	Identification of the cyclic-nucleotide-binding domain as a conserved determinant of ion-channel cell-surface localization.	KCNH7 KCNH2	5.09e-05	3	144	2	15961404
Pubmed	Differential effects of NOX4 and NOX1 on immune cell-mediated inflammation in the aortic sinus of diabetic ApoE-/- mice.	NOX4 NOX1	5.09e-05	3	144	2	27190136
Pubmed	T-wave morphology after epinephrine bolus may reveal silent long QT syndrome mutation carriers.	KCNH2 SCN5A	5.09e-05	3	144	2	22560601
Pubmed	Long QT syndrome-associated mutations in intrauterine fetal death.	KCNH2 SCN5A	5.09e-05	3	144	2	23571586
Pubmed	Perturbation of ubiquitin homeostasis promotes macrophage oxidative defenses.	NOX4 NOX1	5.09e-05	3	144	2	31308397
Pubmed	Hepatitis C Virus NS5A Protein Triggers Oxidative Stress by Inducing NADPH Oxidases 1 and 4 and Cytochrome P450 2E1.	NOX4 NOX1	5.09e-05	3	144	2	27200149
Pubmed	Increased oxidative stress mediates the antitumor effect of PARP inhibition in ovarian cancer.	NOX4 NOX1	5.09e-05	3	144	2	29684820
Pubmed	Genetic deletion of Nox4 enhances cancerogen-induced formation of solid tumors.	NOX4 NOX1	5.09e-05	3	144	2	33836590
Pubmed	Mutation Analysis of KCNQ1, KCNH2 and SCN5A Genes in Taiwanese Long QT Syndrome Patients.	KCNH2 SCN5A	5.09e-05	3	144	2	26118593
Pubmed	Post-mortem review and genetic analysis of sudden unexpected death in epilepsy (SUDEP) cases.	KCNH2 SCN5A	5.09e-05	3	144	2	20875080
Pubmed	A Multispecific Investigation of the Metal Effect in Mammalian Odorant Receptors for Sulfur-Containing Compounds.	OR4E2 OR5AR1	5.09e-05	3	144	2	29659735
Pubmed	Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration.	NOX4 NOX1	5.09e-05	3	144	2	20877715
Pubmed	Nox4 is a protective reactive oxygen species generating vascular NADPH oxidase.	NOX4 NOX1	5.09e-05	3	144	2	22456182
Pubmed	A constitutive NADPH oxidase-like system containing gp91phox homologs in human keratinocytes.	NOX4 NOX1	5.09e-05	3	144	2	15102091
Pubmed	HERG K(+) currents in human prolactin-secreting adenoma cells.	KCNH7 KCNH2	5.09e-05	3	144	2	12634931
Pubmed	ABCG1 Attenuates Oxidative Stress Induced by H2O2 through the Inhibition of NADPH Oxidase and the Upregulation of Nrf2-Mediated Antioxidant Defense in Endothelial Cells.	NOX1 NFE2L2	5.09e-05	3	144	2	33344146
Pubmed	A hERG mutation E1039X produced a synergistic lesion on IKs together with KCNQ1-R174C mutation in a LQTS family with three compound mutations.	KCNH2 SCN5A	5.09e-05	3	144	2	29449639
Pubmed	Bimodal role of NADPH oxidases in the regulation of biglycan-triggered IL-1β synthesis.	NOX4 NOX1	5.09e-05	3	144	2	26689330
Pubmed	Interaction of NADPH oxidase 1 with Toll-like receptor 2 induces migration of smooth muscle cells.	NOX4 NOX1	5.09e-05	3	144	2	23749776
Pubmed	Depressive symptoms in the congenital long QT syndrome.	KCNH2 SCN5A	5.09e-05	3	144	2	19551538
Pubmed	Evolution and functional divergence of the anoctamin family of membrane proteins.	ANO5 ANO7	5.09e-05	3	144	2	20964844
Pubmed	Human NLRP3 inflammasome activation is Nox1-4 independent.	NOX4 NOX1	5.09e-05	3	144	2	20407038
Pubmed	Bidirectional sex-dependent regulation of α6 and β3 nicotinic acetylcholine receptors by protein kinase Cε.	CHRNA6 CHRNA3	5.09e-05	3	144	2	32776643
Pubmed	Common Genotypes of Long QT Syndrome in China and the Role of ECG Prediction.	KCNH2 SCN5A	5.09e-05	3	144	2	26496715
Interaction	GCGR interactions	TSPAN15 KNTC1 GPR50 SLC19A2 SLC35G2 WDFY3 COG4	5.59e-06	110	125	7	int:GCGR
Interaction	GPR173 interactions	CELSR2 XPO5 TMEM259 ATP13A3 UNC93B1	1.58e-05	51	125	5	int:GPR173
Interaction	ZNF252P-AS1 interactions	KNTC1 VPS13C FANCA CELSR2	2.22e-05	27	125	4	int:ZNF252P-AS1
Interaction	OPALIN interactions	KNTC1 FLVCR1 ECPAS MROH1 XPO5 ATP13A3 UNC93B1 WDFY3	4.87e-05	209	125	8	int:OPALIN
Interaction	C5AR1 interactions	GPR50 SLC19A2 SLC35G2 TMEM259 ATP13A3 UNC93B1 FUT8	4.98e-05	154	125	7	int:C5AR1
Interaction	SLC2A9 interactions	KNTC1 FLVCR1 ECPAS COG4	5.02e-05	33	125	4	int:SLC2A9
Cytoband	11p15.4	OR51A4 OR51A2 OR52B4 OR51M1 OR51I2 OR52N4 OR51V1	3.56e-06	200	144	7	11p15.4
Cytoband	Ensembl 112 genes in cytogenetic band chr11p15	OR51A4 OR51A2 ZNF195 ANO5 OR51E2 OR52B4 OR51M1 OR51I2 OR52N4 OR51V1	1.28e-05	564	144	10	chr11p15
GeneFamily	Olfactory receptors, family 51	OR51A4 OR51A2 OR51E2 OR51M1 OR51I2 OR51V1	4.12e-07	44	119	6	164
GeneFamily	Olfactory receptors, family 5	OR5D16 OR5M9 OR5K4 OR5AR1 OR5J2 OR5AC2	9.71e-05	112	119	6	152
GeneFamily	Cholinergic receptors nicotinic subunits	CHRNA6 CHRNA2 CHRNA3	1.46e-04	16	119	3	173
GeneFamily	Parkinson disease associated genes\|ATPase orphan transporters	ATP13A4 ATP13A3	4.24e-04	5	119	2	1213
GeneFamily	Neuropeptide receptors	NPBWR1 NPBWR2	1.87e-03	10	119	2	854
GeneFamily	Anoctamins	ANO5 ANO7	1.87e-03	10	119	2	865
GeneFamily	Potassium voltage-gated channels	KCNH7 KCND3 KCNH2	2.30e-03	40	119	3	274
GeneFamily	Olfactory receptors, family 8	OR8U1 OR8U9 OR8D4	4.11e-03	49	119	3	155
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	KNTC1 NPEPPS VPS13C BIRC6 CELSR2 MACF1 DEPDC5 ATP13A3	5.25e-06	180	138	8	M8239
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WNT2B KANK2 OR51E2 RNF150 PTCHD1 KCND3 KCNH2	1.96e-06	183	141	7	61a73de857f4ae02dcba3af348f436f602b28ff2
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WNT2B KANK2 RNF150 KCND3 KCNH2 ATRNL1 DNAH11	2.34e-06	188	141	7	879de94924de978478696fc7838e05a4d795b905
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-myocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WNT2B KANK2 RNF150 KCND3 KCNH2 ATRNL1 DNAH11	2.43e-06	189	141	7	ab7ece0a517499b70b7754720d3e434765363af6
Drug	(endo-N-8-methyl-8-azabicyclo-(3.2.1)oct-3-yl)-2,3-dihydro-3-isopropyl-2-oxo-1H-benzimidazol-1-carboxamide	CACNA1C KCNH2 SCN5A	2.28e-07	3	140	3	ctd:C070189
Drug	pilsicainide	CHRNA6 CHRNA2 CHRNA3 KCNH2 SCN5A	9.16e-06	46	140	5	CID000004820
Drug	AC1L2IZE	CHRNA6 ATP7A CHRNA2 CHRNA3	1.32e-05	24	140	4	CID000072928
Drug	curarine	CHRNA6 CHRNA2 CHRNA3 FANCA	1.84e-05	26	140	4	CID000198004
Drug	Ibutilide	CACNA1C KCNH7 KCNH2	2.65e-05	10	140	3	DB00308
Drug	methylenedioxydimethylamphetamine	CHRNA6 CHRNA2 CHRNA3 UCP1	3.31e-05	30	140	4	CID000551630
Drug	Dns-C6-Cho	CHRNA6 CHRNA2 CHRNA3	3.62e-05	11	140	3	CID000124728
Drug	AC1L9NC9	CHRNA6 CHRNA2 CHRNA3	3.62e-05	11	140	3	CID000449642
Drug	dihydronereistoxin	CHRNA6 CHRNA2 CHRNA3	3.62e-05	11	140	3	CID000121232
Drug	LJP 1082	CHRNA6 CHRNA2 CHRNA3	3.62e-05	11	140	3	CID003037609
Drug	bipinnatin-B	CHRNA6 CHRNA2 CHRNA3	3.62e-05	11	140	3	CID000127363
Drug	Propafenone	KCNH2 SCN5A	3.75e-05	2	140	2	DB01182
Drug	18-methoxycoronaridine	KCNH2 SCN5A	3.75e-05	2	140	2	ctd:C103345
Drug	Ajmaline	KCNH2 SCN5A	3.75e-05	2	140	2	ctd:D000404
Drug	AC1L9P8C	CHRNA6 CHRNA2 CHRNA3	4.81e-05	12	140	3	CID000450864
Drug	SureCN373116	CHRNA6 CHRNA2 CHRNA3	4.81e-05	12	140	3	CID010085732
Drug	disopyramide	CHRNA6 CHRNA2 CHRNA3 KCNH2 SCN5A	5.41e-05	66	140	5	CID000003114
Drug	nereistoxin	CHRNA6 CHRNA2 CHRNA3	6.22e-05	13	140	3	CID000015401
Drug	1-acetyl-4-methylpiperazine methiodide	CHRNA6 CHRNA2 CHRNA3	6.22e-05	13	140	3	CID004392675
Drug	C-toxiferine-I	CHRNA6 CHRNA2 CHRNA3	6.22e-05	13	140	3	CID005089093
Drug	bipinnatin-A	CHRNA6 CHRNA2 CHRNA3	6.22e-05	13	140	3	CID000196603
Drug	bipinnatin-C	CHRNA6 CHRNA2 CHRNA3	6.22e-05	13	140	3	CID000129977
Drug	AC1NSKJI	CHRNA6 BIRC6 CHRNA2 CHRNA3 SCN5A	6.25e-05	68	140	5	CID005311391
Drug	desloratadine	CHRNA6 CYSLTR2 CHRNA2 CHRNA3 KCNH2	6.70e-05	69	140	5	CID000124087
Drug	1,2-dichlorohexafluorocyclobutane	CHRNA6 CHRNA2 CHRNA3 KCNH2	7.73e-05	37	140	4	CID000009643
Drug	2,3-dichlorooctafluorobutane	CHRNA6 CHRNA2 CHRNA3	7.88e-05	14	140	3	CID000078982
Drug	LNF 209	CHRNA6 CHRNA2 CHRNA3	7.88e-05	14	140	3	CID000132666
Drug	anatoxin-a hydrochloride	CHRNA6 CHRNA2 CHRNA3	9.81e-05	15	140	3	CID000135265
Drug	SAD-128	CHRNA6 CHRNA2 CHRNA3	9.81e-05	15	140	3	CID000162008
Drug	N-methylcytisine	CHRNA6 CHRNA2 CHRNA3	9.81e-05	15	140	3	CID000234566
Drug	aa373	CHRNA6 CHRNA2 CHRNA3	9.81e-05	15	140	3	CID000191672
Drug	(-)-pictamine	CHRNA6 CHRNA2 CHRNA3	9.81e-05	15	140	3	CID006918623
Drug	(-)-lepadin B	CHRNA6 CHRNA2 CHRNA3	9.81e-05	15	140	3	CID006918624
Drug	UB-165	CHRNA6 CHRNA2 CHRNA3	9.81e-05	15	140	3	CID004694339
Drug	Ibogaine	KCNH2 SCN5A	1.12e-04	3	140	2	ctd:D007050
Drug	3-(trifluoromethyl)-3-(m-iodophenyl)diazirine	CHRNA6 CHRNA2 CHRNA3	1.20e-04	16	140	3	CID000123866
Drug	AC1L2SVN	CHRNA6 CHRNA2 CHRNA3	1.20e-04	16	140	3	CID000127922
Drug	Verapamil	CACNA1C KCNH2 SCN5A	1.20e-04	16	140	3	DB00661
Drug	benzoquinonium	CHRNA6 CHRNA2 CHRNA3	1.20e-04	16	140	3	CID000009393
Drug	PNU-282,987	CHRNA6 CHRNA2 CHRNA3	1.20e-04	16	140	3	CID004655349
Drug	bepridil	CACNA1C TPCN2 BIRC6 KCND3 KCNH2 SCN5A	1.31e-04	126	140	6	CID000002351
Drug	Nsc36388	CHRNA6 CHRNA2 CHRNA3	1.45e-04	17	140	3	CID000014954
Drug	metoclopramide	CHRNA6 HTR3E CHRNA2 CHRNA3 KCNH2	1.71e-04	84	140	5	CID000004168
Drug	AC1O8PVM	CHRNA6 CHRNA2 CHRNA3	1.74e-04	18	140	3	CID000004989
Drug	ABT-594	CHRNA6 CHRNA2 CHRNA3	1.74e-04	18	140	3	CID003075702
Drug	AC1LCVGE	CHRNA6 CHRNA2 CHRNA3	1.74e-04	18	140	3	CID000656712
Drug	benzetimide	CHRNA6 CHRNA2 CHRNA3	1.74e-04	18	140	3	CID000021846
Disease	Brugada Syndrome (disorder)	CACNA1C KCND3 KCNH2 SCN5A	3.05e-06	24	125	4	C1142166
Disease	congenital myasthenic syndrome (implicated_via_orthology)	CHRNA6 CHRNA2 CHRNA3	3.99e-05	16	125	3	DOID:3635 (implicated_via_orthology)
Disease	Torsades de Pointes	KCNH2 SCN5A	5.33e-05	3	125	2	C0040479
Disease	Parkinson's disease (implicated_via_orthology)	ATP13A4 NPBWR1 NPBWR2 VPS13C NOX1 ATP13A3	5.74e-05	157	125	6	DOID:14330 (implicated_via_orthology)
Disease	ovarian cancer (is_implicated_in)	RAD51 FANCA CCNG1 JUP	9.51e-05	56	125	4	DOID:2394 (is_implicated_in)
Disease	juvenile-onset Parkinson's disease (implicated_via_orthology)	ATP13A4 ATP13A3	1.06e-04	4	125	2	DOID:0060893 (implicated_via_orthology)
Disease	Kufor-Rakeb syndrome (implicated_via_orthology)	ATP13A4 ATP13A3	1.06e-04	4	125	2	DOID:0060556 (implicated_via_orthology)
Disease	traumatic brain injury (biomarker_via_orthology)	CCNG1 NOX1 NFE2L2	1.41e-04	24	125	3	DOID:0081292 (biomarker_via_orthology)
Disease	Cardiac Arrhythmia	CACNA1C KCND3 KCNH2	1.59e-04	25	125	3	C0003811
Disease	tumor necrosis factor-alpha measurement, chronic obstructive pulmonary disease	RNF150 FUT8	1.77e-04	5	125	2	EFO_0000341, EFO_0004684
Disease	squamous cell carcinoma	TPCN2 NOX4 DUSP22 DNAH11	1.91e-04	67	125	4	EFO_0000707
Disease	heart conduction disease (implicated_via_orthology)	KCNH7 MMEL1 KCNH2	3.36e-04	32	125	3	DOID:10273 (implicated_via_orthology)
Disease	long QT syndrome (is_implicated_in)	KCNH2 SCN5A	3.69e-04	7	125	2	DOID:2843 (is_implicated_in)
Disease	arrhythmogenic right ventricular cardiomyopathy (is_marker_for)	JUP SCN5A	3.69e-04	7	125	2	DOID:0050431 (is_marker_for)
Disease	Autosomal Dominant Nocturnal Frontal Lobe Epilepsy	CHRNA2 DEPDC5	3.69e-04	7	125	2	C3696898
Disease	Brugada syndrome	CACNA1C SCN5A	4.90e-04	8	125	2	cv:C1142166
Disease	primary ovarian insufficiency (is_implicated_in)	FANCA XPO5	4.90e-04	8	125	2	DOID:5426 (is_implicated_in)
Disease	JT interval	KANK2 RNF150 KCND3 KCNH2 SCN5A CLUH	6.76e-04	248	125	6	EFO_0007885
Disease	sunburn	TPCN2 NOX4 DUSP22 FANCA	7.55e-04	96	125	4	EFO_0003958
Disease	Secondary Biliary Cholangitis	MMEL1 NFE2L2 SLC51A	7.55e-04	42	125	3	C0238065
Disease	Biliary cirrhosis	MMEL1 NFE2L2 SLC51A	7.55e-04	42	125	3	C0023892
Disease	Biliary Cirrhosis, Primary, 1	MMEL1 NFE2L2 SLC51A	7.55e-04	42	125	3	C4551595
Disease	susceptibility to infectious disease measurement	FSTL4 RNF150 ATRNL1	7.55e-04	42	125	3	EFO_0008422
Disease	Anemia, Sickle Cell	CACNA1C NFE2L2	7.84e-04	10	125	2	C0002895
Disease	long QT syndrome (implicated_via_orthology)	KCNH7 KCNH2	7.84e-04	10	125	2	DOID:2843 (implicated_via_orthology)
Disease	Shortened QT interval	CACNA1C KCNH2	9.55e-04	11	125	2	C0151879
Disease	Congenital long QT syndrome	KCNH2 SCN5A	9.55e-04	11	125	2	cv:C1141890
Disease	Long QT Syndrome	KCNH2 SCN5A	9.55e-04	11	125	2	C0023976
Disease	suntan	TPCN2 NOX4 DUSP22 FANCA	9.82e-04	103	125	4	EFO_0004279
Disease	homocysteine measurement	NOX4 FANCA FERD3L	9.86e-04	46	125	3	EFO_0004578
Disease	S-6-hydroxywarfarin measurement	GALR1 ADAM21 SMYD1 VPS13C CHD9 FERD3L STEAP1B	1.00e-03	368	125	7	EFO_0803326
Disease	Primary biliary cirrhosis	MMEL1 NFE2L2 SLC51A	1.05e-03	47	125	3	C0008312
Disease	TOBACCO ADDICTION, SUSCEPTIBILITY TO (finding)	CHRNA6 CHRNA3	1.14e-03	12	125	2	C1861063
Disease	Long QT syndrome	KCNH2 SCN5A	1.14e-03	12	125	2	cv:C0023976
Disease	Congestive heart failure	NOX4 NOX1 NFE2L2 UCP1	1.25e-03	110	125	4	C0018802
Disease	Heart failure	NOX4 NOX1 NFE2L2 UCP1	1.25e-03	110	125	4	C0018801
Disease	Left-Sided Heart Failure	NOX4 NOX1 NFE2L2 UCP1	1.25e-03	110	125	4	C0023212
Disease	Heart Failure, Right-Sided	NOX4 NOX1 NFE2L2 UCP1	1.25e-03	110	125	4	C0235527
Disease	Heart Decompensation	NOX4 NOX1 NFE2L2 UCP1	1.25e-03	110	125	4	C1961112
Disease	Myocardial Failure	NOX4 NOX1 NFE2L2 UCP1	1.25e-03	110	125	4	C1959583
Disease	IGFBP-1 measurement	ANO5 TGFBRAP1	1.35e-03	13	125	2	EFO_0005118
Disease	Brugada Syndrome 1	KCND3 SCN5A	1.35e-03	13	125	2	C4551804
Disease	neuronal ceroid lipofuscinosis (implicated_via_orthology)	ATP13A4 ATP13A3	1.57e-03	14	125	2	DOID:14503 (implicated_via_orthology)
Disease	T wave morphology measurement	KCNH2 SCN5A	1.57e-03	14	125	2	EFO_0008398
Disease	P wave duration	KCND3 SCN5A	1.80e-03	15	125	2	EFO_0005094
Disease	Romano-Ward Syndrome	KCNH2 SCN5A	2.05e-03	16	125	2	C0035828
Disease	filaggrin gene expression measurement	ZNF618 RNF150	2.05e-03	16	125	2	EFO_0020899
Disease	celiac disease	TPTE DUSP22 MMEL1 ANKFN1	2.06e-03	126	125	4	EFO_0001060
Disease	non-alcoholic steatohepatitis (biomarker_via_orthology)	NOX4 NFE2L2	2.32e-03	17	125	2	DOID:0080547 (biomarker_via_orthology)
Disease	Seizures	CUL4B ATP7A CHRNA3 MACF1 FUT8	2.41e-03	218	125	5	C0036572
Disease	skin sensitivity to sun	DUSP22 FANCA	2.90e-03	19	125	2	EFO_0004795
Disease	Benign Neoplasm	PLEKHS1 BIRC6 KCNH2	3.04e-03	68	125	3	C0086692
Disease	Neoplasms	PLEKHS1 BIRC6 KCNH2	3.04e-03	68	125	3	C0027651
Disease	venous thromboembolism, plasminogen activator inhibitor 1 measurement	TSPAN15 TRIM56	3.55e-03	21	125	2	EFO_0004286, EFO_0004792
Disease	Colonic Neoplasms	ATP7A NOX4 NOX1 KCNH2	4.05e-03	152	125	4	C0009375

Protein segments in the cluster

Peptide	Gene	Start	Entry
MLVFTLVLRSIYIVT	ACER3	151	Q9NUN7
IFSRMRTLVATVLDF	ACY3	191	Q96HD9
SLVVTSMVAVIVYRL	ANO5	471	Q75V66
SMVAVIVYRLSVFAT	ANO5	476	Q75V66
VVMLVSRLLDYVATV	BIRC6	2171	Q9NR09
EYLLFTMIFVTLSIV	CHRNA3	306	P32297
FRLYLLFMASSIITV	HTR3E	436	A5X5Y0
NDITRVLYTFVLMPI	ADGRA2	421	Q96PE1
FMRTTVLIADLLIYI	ALG6	111	Q9Y672
SRIIQYLFLISVITM	ALG6	436	Q9Y672
MAVDGTLVYIRVTLL	ADAM21	1	Q9UKJ8
MSIVSIVSSLYSIRK	ATP13A3	241	Q9H7F0
IMSIISISLTVYDLR	ATP13A4	231	Q4VNC1
LTEVTLMNARSELYL	COG4	356	Q9H9E3
SLLVSVLEYQTAVMR	COPB2	586	P35606
MLSTYQTDFILVRER	CASTOR2	116	A6NHX0
MDTILVFSLIIASYD	C17orf78	1	Q8N4C9
TTETARLRYFMELLL	DNAH11	2486	Q96DT5
YLLFTMIFVTLSIVI	CHRNA2	331	Q15822
MESLFRDIYSRVVAS	BTBD11	241	A6QL63
VSMSVFLYILAARAS	CELSR2	2531	Q9HCU4
SILDCSIIRVEYSLM	ARRDC3	276	Q96B67
MDVLIVLATTIAFAY	ATP7A	746	Q04656
MVESRYALLIVDSAT	RAD51	211	Q06609
FVSYTMTVIAINFIV	RRH	186	O14718
ILTSYAFIIVTTLKM	OR5D16	216	Q8NGK9
LTDEVSFLRTLYEME	KRT76	311	Q01546
LIRISQYRFTVSDLM	CCNG1	121	P51959
VSIILYRAIMAIVVS	ANO7	516	Q6IWH7
ILMVTSATEFIRRSY	NOX1	186	Q9Y5S8
SMFEVILTRIRSFLD	CYFIP1	1091	Q7L576
RVVFRSTSAMVYIFI	DEPDC5	161	O75140
EKVSSVFYTTVILML	OR8D4	271	Q8NGM9
VTDTLVIAVMALDRY	OR1B1	111	Q8NGR6
VSYTRIIITILRMSS	OR10A7	216	Q8NGE5
SMYILRSYILLLTAV	OR11H4	221	Q8NGC9
ASYARVLIVVFQMSS	OR2AK2	231	Q8NG84
ITNSYTMILRAVVSL	OR52N4	216	Q8NGI2
TACVMIFTVEYLLRL	KCND3	231	Q9UK17
SRMTVLYVDTIGFLS	GTPBP6	341	O43824
MFIIDILINFRTTYV	KCNH7	461	Q9NS40
RVYVIFDLPTTVSMI	KATNIP	1486	O60303
IMFIVDILINFRTTY	KCNH2	461	Q12809
FVVSLSVADMLVAIY	GPR50	66	Q13585
AQRTLMEALVASYLI	ECPAS	476	Q5VYK3
YLTSILEVLTRDLME	PLXNC1	1101	O60486
SLVIISFVVITLSYM	OR14L1P	206	Q8NHC6
MLVFPVAIIITSYAR	OR2M7	206	Q8NG81
STILLAMAFDRYVAI	OR51E2	111	Q9H255
MFISLSYFLIIRTVL	OR51E2	211	Q9H255
LSYVLILRSVMATAS	OR51I2	216	Q9H344
VFTVMLDLVLIALSY	OR51M1	216	Q9H341
SSVLLTMAFDRYIAI	OR51V1	121	Q9H2C8
MSTVVLDVVLIFISY	OR52B4	206	Q8NGK2
EIVLLISMSFDRYVA	OR4K3	111	Q96R72
QLSTLYLEVFSMLRD	NFE2L2	556	Q16236
ASVLTVMLITFDRYL	GPR119	91	Q8TDV5
AFMLSDDEIYSLRII	KNTC1	886	P50748
SLFVLFLVMYVVTVL	OR2F1	26	Q13607
VLESSVLLIMSFDRF	OR51A2	111	Q8NGJ7
VLESSVLLIMSFDRF	OR51A4	111	Q8NGJ6
TVLFIVVLSFYMVSI	OR2C3	26	Q8N628
IAMATFLTVIISYIF	OR5J2	206	Q8NH18
AYLQFMVSVATLLRE	MMEL1	276	Q495T6
SVRTLYLVSTTVDRM	MROH1	466	Q8NDA8
LILTIMSFDRYLTIC	OR6X1	111	Q8NH79
AVMSVDRYLVVLATV	NPBWR2	136	P48146
LLIVFVSYMFIISAI	OR8U9	211	P0C7N5
LVRMLSSPVESVLFY	JUP	231	P14923
AVVSVSYIMIAQTLR	GPR75	216	O95800
ITQEFMDLRTRYTAL	MACF1	1381	Q9UPN3
MDLRTRYTALVTLTT	MACF1	1386	Q9UPN3
LFLMITASTYAIRVS	NOX4	171	Q9NPH5
VAMEYLQSASRILTR	PTPRR	366	Q15256
LLMAVAVFLVYRTIT	PACC1	76	Q9H813
PTLMTIIISYTRVLF	OR5AC2	211	Q9NZP5
SLVLVEMTITSFYAV	SLC51A	111	Q86UW1
ASTLFTVLTYLVDMR	FZD7	266	O75084
VSIFTLAAMSVDRYV	GALR1	121	P47211
YLLFTMIFVTLSIVV	CHRNA6	306	Q15825
AYRFQAIITTFEMIL	CHD9	966	Q3L8U1
VYEILRLLVTDMSDA	HAT1	331	O14929
TSIFTLEIILKMTAY	CACNA1C	961	Q13936
ETLRLAIVYISFMTE	FERD3L	141	Q96RJ6
TSLYRRLFVMLSAEE	FANCA	356	O15360
SSLTLREFYMAFQVV	FSTL4	231	Q6MZW2
LSFMSYDEISQLRLV	FBXO28	76	Q9NVF7
LSYIMALTRILAEAE	ATOH7	86	Q8N100
MLVILYSRVGRSVTD	CXCR1	61	P25024
LDSRDVVMIIIFGYS	ATRNL1	421	Q5VV63
IGMVIFTFTLDLRYI	FLVCR1	411	Q9Y5Y0
GVSRSVTLVIAYIMT	DUSP22	91	Q9NRW4
AYIMLAVEVRSLSSL	MBOAT4	391	Q96T53
RTSYLAAFAIMVIFT	TMEM259	301	Q4ZIN3
VTFRAMSARLLDYVV	KANK2	646	Q63ZY3
ELRFAYMVTTVLLSV	CYP20A1	411	Q6UW02
AIVVCALIISTFYMR	GRAMD2B	351	Q96HH9
MIYVGRRATVASFLI	SLC22A20P	391	A6NK97
FRIIYMLLITIATFQ	SLC19A2	396	O60779
ARTPVMSTYLVAFVV	NPEPPS	236	P55786
MTLTRVELLTFQERY	CARD11	166	Q9BXL7
YLGIINMFFIRETTS	C2CD5	891	Q86YS7
IMIRSIFLFLDRTYV	CUL4B	301	Q13620
FLTVMSADRYLVVLA	NPBWR1	126	P48145
TDRVLSLFYTVITPM	OR10P1	271	Q8NGE3
SLLERNITVTMYITI	RNF150	181	Q9ULK6
LLIVFVSYMFIISAI	OR8U1	211	Q8NH10
FMIAYGTQRTLILES	FUT8	231	Q9BYC5
LTVFFMIIYVLESLT	TAS2R16	6	Q9NYV7
IMESRILTFLETYLA	TCP11L1	441	Q9NUJ3
RIFAYLMAVILSVTL	RNF183	161	Q96D59
LSDVTLMISVYNRRT	SYT16	586	Q17RD7
YLVTSLILVVTMAIL	PTCHD1	271	Q96NR3
IIRTLSTFRNYIMDF	RBP1	51	P09455
LTTALSMIVYRSIKE	SLC35G2	266	Q8TBE7
IVTEVMVLFTVLVYT	PKDREJ	1001	Q9NTG1
LRMLSIVSEVLSYLQ	SMYD1	351	Q8NB12
LDFSVIIMAYTTEFV	SCN5A	196	Q14524
DTLLLTVMAYDRFVA	OR7D2	111	Q96RA2
ISYTFILVAIIRMRS	OR5AR1	216	Q8NGP9
YTLIVVAVLRMRSAD	OR5M9	216	Q8NGP3
LLFVVFSAIYLVTMV	OR5K4	26	A6NMS3
VMASLTFLYTLLREV	STEAP1B	61	Q6NZ63
LIVTIREVEMLYSFF	ANKFN1	546	Q8N957
IYFLTVLSVVRFLAM	CYSLTR2	126	Q9NS75
LMYLFVITAEDRQVS	CLUH	236	O75153
EVMSIRTTNREYFLI	PLEKHS1	96	Q5SXH7
LMRSVIINCTELVTY	UCP1	181	P25874
RFLMSYLNEVRSTEV	TGFBRAP1	426	Q8WUH2
DLDLTYVTERIIAMS	TPTE	236	P56180
QRFLTADMALVATVY	TSR1	641	Q2NL82
LVTLVAAAVSYLRME	UNC93B1	501	Q9H1C4
NVLSEFVMSEIRTVY	ZNF618	601	Q5T7W0
TRIAVYLMTFLIVTV	TMEM175	76	Q9BSA9
FVYITSLLVAMERSL	WDFY3	651	Q8IZQ1
FLAVVTSYMVILVSL	OR4E2	211	Q8NGC2
MFSVITSYILFRATR	RNF175	111	Q8N4F7
LTLLYITRVEDIIME	TSPAN15	251	O95858
TVLERMQRFFSTLYE	XPO5	831	Q9HAV4
ATMRTFDLTVVSYLK	VPS13C	946	Q709C8
VMIIIYFSRLLRSDF	TLCD1	216	Q96CP7
SRLITLYLTMLVTFT	UBE3B	156	Q7Z3V4
VSVFGYSLIIVIRSM	TMC2	346	Q8TDI7
RVVLMVFSLVSVTYG	XKRX	201	Q6PP77
LTFLLRPETVSMVIY	ZP2	341	Q05996
MTLLTFRDVAIEFSL	ZNF195	1	O14628
ATYQMTVELLFRDIL	TPCN2	716	Q8NHX9
RVVVLLDISATNSMY	VWA3A	511	A6NCI4
VMLRSSREAAFVYAI	WNT2B	131	Q93097
RVTTMVDGRYLVVSL	TRIM56	726	Q9BRZ2