Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

SELE SYT3 PCDHGA2 ITSN1 CAPSL CAPS ACTN1 TENM2 CEMIP2 HPCA SLC25A12 HMCN1 NRXN1 OTOF HPCAL1 LRP2 TESC EML1 PADI2

2.13e-0674914519GO:0005509
GeneOntologyMolecularFunctionneuroligin family protein binding

NRXN3 NRXN1 NRXN2

3.71e-0651453GO:0097109
GeneOntologyMolecularFunctionGABA-A receptor activity

GABRB1 GABRD GABRG2 GABRG3

9.50e-06191454GO:0004890
GeneOntologyMolecularFunctionGABA receptor activity

GABRB1 GABRD GABRG2 GABRG3

1.76e-05221454GO:0016917
GeneOntologyMolecularFunctionpalmitoleoyltransferase activity

PORCN CPT1A

5.24e-0521452GO:1990698
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GABRB1 GABRD GABRG2 GABRG3 GRIA4

5.82e-05571455GO:1904315
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GABRB1 GABRD GABRG2 GABRG3 GRIA4

7.46e-05601455GO:0099529
GeneOntologyMolecularFunctionneurotransmitter receptor activity

GABRB1 GABRD GABRG2 GABRG3 GRIA4 GPR158

8.99e-051001456GO:0030594
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GABRB1 GABRD GABRG2 GABRG3 GRIA4

1.10e-04651455GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GABRB1 GABRD GABRG2 GABRG3 GRIA4

1.10e-04651455GO:0022824
GeneOntologyMolecularFunctionribonucleoside binding

POLR3B POLR1B

1.56e-0431452GO:0032549
GeneOntologyMolecularFunctionArp2/3 complex binding

JMY CTTN WASF1

1.96e-04161453GO:0071933
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

GABRB1 GABRD GABRG2 GABRG3 GRIA4

2.16e-04751455GO:0098960
GeneOntologyMolecularFunctionhexosaminidase activity

NAGLU CEMIP2 CEMIP

2.37e-04171453GO:0015929
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GABRB1 GABRD GABRG2 GABRG3 GRIA4

2.45e-04771455GO:0005230
GeneOntologyMolecularFunctionGABA-gated chloride ion channel activity

GABRB1 GABRG2 GABRG3

2.83e-04181453GO:0022851
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

GABRB1 SELE GABRD GABRG2 GABRG3 SEMA4D ERBB3 FLT3 OR5I1 NTRK1 CCR9 INSRR OR1A2 GRIA4 NRXN3 NRXN1 NRXN2 GPR158 PAX8 CXCR4 OR6C4 SORL1

3.05e-04135314522GO:0004888
GeneOntologyMolecularFunctionDNA/RNA hybrid binding

POLR3B POLR1B

5.16e-0451452GO:0071667
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

ERBB3 FLT3 NTRK1 INSRR TEC TXK

6.72e-041451456GO:0004713
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GABRB1 GRIA4 KCNMA1

6.79e-04241453GO:0099507
GeneOntologyMolecularFunctionneuregulin binding

ERBB3 ITGB4

7.71e-0461452GO:0038132
GeneOntologyMolecularFunctionchemorepellent activity

DPP4 SEMA4D SEMA3D

1.19e-03291453GO:0045499
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

ERBB3 FLT3 NTRK1 INSRR

1.28e-03651454GO:0004714
GeneOntologyMolecularFunctionDNA-directed 5'-3' RNA polymerase activity

POLR3H POLR3B POLR1B

1.32e-03301453GO:0003899
GeneOntologyMolecularFunction5'-3' RNA polymerase activity

POLR3H POLR3B POLR1B

1.59e-03321453GO:0034062
GeneOntologyMolecularFunctionRNA polymerase activity

POLR3H POLR3B POLR1B

1.59e-03321453GO:0097747
GeneOntologyMolecularFunctionkinase regulator activity

ERBB3 FLT3 ITSN1 RICTOR MADD KIDINS220 PKIA TESC

1.77e-033051458GO:0019207
GeneOntologyMolecularFunctionhyalurononglucosaminidase activity

CEMIP2 CEMIP

1.82e-0391452GO:0004415
GeneOntologyBiologicalProcesscardiac ventricle development

MATR3 NAGLU MED1 GRHL2 NFATC1 PAX8 CXCR4 RBPJ LRP2

1.57e-061611409GO:0003231
GeneOntologyBiologicalProcesscardiac chamber development

MATR3 NAGLU MED1 GRHL2 NFATC1 PAX8 CXCR4 RBPJ LRP2

1.48e-052121409GO:0003205
GeneOntologyBiologicalProcesshemopoiesis

DPP4 FLT3 CEBPD NTRK1 CCR9 NAGLU ACTN1 MED1 ITGAM SOX13 OPA1 RHAG CHUK TXK NFATC1 DROSHA PTPRQ RBPJ TESC EML1 PREX1 HSP90AA1

2.58e-05122314022GO:0030097
GeneOntologyBiologicalProcessleukocyte differentiation

DPP4 FLT3 NTRK1 CCR9 NAGLU MED1 ITGAM SOX13 OPA1 CHUK TXK NFATC1 DROSHA RBPJ TESC PREX1 HSP90AA1

2.59e-0578914017GO:0002521
GeneOntologyBiologicalProcessmononuclear cell differentiation

DPP4 FLT3 NTRK1 CCR9 NAGLU MED1 ITGAM SOX13 OPA1 TXK NFATC1 DROSHA RBPJ PREX1 HSP90AA1

3.07e-0564014015GO:1903131
GeneOntologyBiologicalProcessepithelial tube morphogenesis

APAF1 ETV4 MED1 ITGAX GRHL2 OPA1 NFATC1 PAX8 CXCR4 RBPJ LRP2 GRHL3

3.10e-0542114012GO:0060562
GeneOntologyBiologicalProcessventricular septum development

MATR3 NFATC1 PAX8 CXCR4 RBPJ LRP2

3.65e-05911406GO:0003281
GeneOntologyBiologicalProcesssynapse organization

GABRG2 GABRG3 SEMA4D NTRK1 ITSN1 ACTN1 CSMD2 ITGAM OPA1 NRXN3 NRXN1 NRXN2 GPR158 CTTN WASF1

6.64e-0568514015GO:0050808
GeneOntologyBiologicalProcessadult behavior

GABRG2 NAGLU CREBBP GIP NRXN3 NRXN1 NRXN2 KCNMA1

7.55e-052031408GO:0030534
GeneOntologyBiologicalProcesspostsynaptic density assembly

CSMD2 NRXN3 NRXN1 NRXN2

8.05e-05341404GO:0097107
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

APAF1 NAGLU ETV4 MED1 ITGAX GRHL2 OPA1 CHUK NFATC1 PAX8 CXCR4 RBPJ LRP2 GRHL3

8.37e-0561914014GO:0002009
GeneOntologyBiologicalProcessgamma-aminobutyric acid signaling pathway

GABRB1 GABRD GABRG2 GABRG3

9.04e-05351404GO:0007214
GeneOntologyBiologicalProcessreceptor-mediated endocytosis

SELE DPP4 ITSN1 ITGAM HPCA CLTC LRP2 CTTN WASF1 SORL1

1.04e-0433714010GO:0006898
GeneOntologyBiologicalProcesscell junction organization

GABRG2 GABRG3 SEMA4D NTRK1 ITSN1 ACTN1 CSMD2 ITGAM HNF4A GRHL2 ITGB4 OPA1 NRXN3 NRXN1 NRXN2 GPR158 CTTN WASF1

1.08e-0497414018GO:0034330
GeneOntologyBiologicalProcessaxon guidance

SEMA4D NTRK1 ETV4 TENM2 SEMA3D NRXN3 NRXN1 CXCR4 LRP2

1.46e-042851409GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

SEMA4D NTRK1 ETV4 TENM2 SEMA3D NRXN3 NRXN1 CXCR4 LRP2

1.50e-042861409GO:0097485
GeneOntologyBiologicalProcessneuron cell-cell adhesion

NRXN3 NRXN1 NRXN2

1.61e-04161403GO:0007158
GeneOntologyBiologicalProcesstissue morphogenesis

APAF1 NAGLU ETV4 EXT2 MED1 ITGAX GRHL2 OPA1 CHUK NFATC1 PAX8 CXCR4 RBPJ LRP2 GRHL3

1.80e-0475014015GO:0048729
GeneOntologyBiologicalProcesspostsynaptic specialization assembly

CSMD2 NRXN3 NRXN1 NRXN2

2.24e-04441404GO:0098698
GeneOntologyBiologicalProcessexcitatory synapse assembly

CSMD2 NRXN3 NRXN1 NRXN2

2.66e-04461404GO:1904861
GeneOntologyBiologicalProcessB-1a B cell differentiation

DPP4 NFATC1

2.72e-0441402GO:0002337
GeneOntologyBiologicalProcessneuroligin clustering involved in postsynaptic membrane assembly

NRXN1 NRXN2

2.72e-0441402GO:0097118
GeneOntologyBiologicalProcesspositive regulation of gene expression

ERBB3 FLT3 CYP3A4 ETV4 MED1 HNF4A ITGAX CREBBP OPA1 HNRNPCL3 CHUK TXK POLR3B NRXN1 NFATC1 DROSHA RBPJ TESC GRHL3 PADI2 HSP90AA1 SORL1

2.96e-04144614022GO:0010628
GeneOntologyBiologicalProcesslymphocyte differentiation

DPP4 FLT3 NTRK1 CCR9 SOX13 OPA1 TXK NFATC1 DROSHA RBPJ PREX1 HSP90AA1

3.05e-0453714012GO:0030098
GeneOntologyBiologicalProcesscardiac septum development

MATR3 NFATC1 PAX8 CXCR4 RBPJ LRP2

3.09e-041341406GO:0003279
GeneOntologyBiologicalProcesscardiac ventricle morphogenesis

NAGLU MED1 GRHL2 RBPJ LRP2

3.34e-04881405GO:0003208
GeneOntologyBiologicalProcessinner ear development

CEBPD NAGLU HPCA PAX8 PTPRQ RBPJ KCNMA1 GRHL3

3.40e-042531408GO:0048839
GeneOntologyBiologicalProcessmorphogenesis of an endothelium

ITGAX CXCR4 RBPJ

3.72e-04211403GO:0003159
GeneOntologyBiologicalProcessendothelial tube morphogenesis

ITGAX CXCR4 RBPJ

3.72e-04211403GO:0061154
GeneOntologyBiologicalProcesscell adhesion mediated by integrin

DPP4 ITGAM ITGAX ITGB4 TESC

3.91e-04911405GO:0033627
GeneOntologyBiologicalProcessprotein retention in Golgi apparatus

VPS13C SORL1

4.51e-0451402GO:0045053
GeneOntologyBiologicalProcessgephyrin clustering involved in postsynaptic density assembly

NRXN1 NRXN2

4.51e-0451402GO:0097116
GeneOntologyCellularComponentsynaptic membrane

GABRB1 GABRD GABRG2 GABRG3 ERBB3 SYT3 ITSN1 GRIA4 CSMD2 ITGB4 TENM2 NRXN3 NRXN1 NRXN2 OTOF GPR158 CLTC KCNMA1

1.01e-0758314318GO:0097060
GeneOntologyCellularComponentreceptor complex

GABRB1 GABRD GABRG2 GABRG3 SEMA4D ERBB3 FLT3 NTRK1 INSRR PORCN GRIA4 ITGAM ITGAX ITGB4 CHUK PTPRQ LRP2

4.98e-0758114317GO:0043235
GeneOntologyCellularComponentpresynaptic active zone membrane

GABRB1 GRIA4 NRXN3 NRXN1 NRXN2 OTOF KCNMA1

1.07e-06781437GO:0048787
GeneOntologyCellularComponentGABA-A receptor complex

GABRB1 GABRD GABRG2 GABRG3

7.51e-06191434GO:1902711
GeneOntologyCellularComponentGABA receptor complex

GABRB1 GABRD GABRG2 GABRG3

1.15e-05211434GO:1902710
GeneOntologyCellularComponentglutamatergic synapse

GABRD GABRG2 CNNM2 ITSN1 PORCN GRIA4 ACTN1 CSMD2 ITGB4 TENM2 HPCA NRXN3 NRXN1 NRXN2 DROSHA CLTC KCNMA1 CTTN

1.22e-0581714318GO:0098978
GeneOntologyCellularComponentclathrin-coated pit

SELE ITSN1 CEMIP CLTC LRP2 CTTN

1.83e-05801436GO:0005905
GeneOntologyCellularComponentpresynaptic membrane

GABRB1 ITSN1 GRIA4 NRXN3 NRXN1 NRXN2 OTOF GPR158 CLTC KCNMA1

2.16e-0527714310GO:0042734
GeneOntologyCellularComponentaxon

GABRD GABRG2 NTRK1 ITSN1 INSRR GRIA4 TENM2 OPA1 MADD HPCA NRXN1 CXCR4 KCNMA1 LRP2 SLC2A13 CTTN PREX1 HSP90AA1

3.85e-0589114318GO:0030424
GeneOntologyCellularComponentpresynaptic active zone

GABRB1 GRIA4 NRXN3 NRXN1 NRXN2 OTOF KCNMA1

5.33e-051411437GO:0048786
GeneOntologyCellularComponentpostsynapse

GABRB1 GABRD GABRG2 GABRG3 ERBB3 SYT3 ITSN1 GRIA4 ACTN1 CSMD2 ITGB4 TENM2 HPCA GPR158 DROSHA CLTC KCNMA1 CTTN WASF1

6.72e-05101814319GO:0098794
GeneOntologyCellularComponentpostsynaptic membrane

GABRB1 GABRD GABRG2 GABRG3 ERBB3 GRIA4 CSMD2 ITGB4 TENM2 GPR158 KCNMA1

1.11e-0440514311GO:0045211
GeneOntologyCellularComponentGABA-ergic synapse

GABRB1 GABRD GABRG2 GABRG3 SEMA4D NRXN3 NRXN1

1.38e-041641437GO:0098982
GeneOntologyCellularComponentcell leading edge

GABRG2 GABRG3 DPP4 ITSN1 ACTN1 ITGB4 JMY HPCA CXCR4 TESC CTTN WASF1

1.72e-0450014312GO:0031252
GeneOntologyCellularComponentdistal axon

ITSN1 GRIA4 TENM2 NRXN1 CXCR4 KCNMA1 LRP2 SLC2A13 CTTN PREX1 HSP90AA1

2.06e-0443514311GO:0150034
GeneOntologyCellularComponentdendrite

GABRB1 GABRD GABRG2 GABRG3 NTRK1 ITSN1 GRIA4 ACTN1 TENM2 OPA1 HPCA KCNMA1 LRP2 CTTN PREX1 HSP90AA1

2.65e-0485814316GO:0030425
GeneOntologyCellularComponentsomatodendritic compartment

GABRB1 GABRD GABRG2 GABRG3 PDE1A NTRK1 ITSN1 GRIA4 ACTN1 TENM2 OPA1 GIP HPCA NRXN1 KCNMA1 LRP2 CTTN PREX1 HSP90AA1 SORL1

2.67e-04122814320GO:0036477
GeneOntologyCellularComponentdendritic tree

GABRB1 GABRD GABRG2 GABRG3 NTRK1 ITSN1 GRIA4 ACTN1 TENM2 OPA1 HPCA KCNMA1 LRP2 CTTN PREX1 HSP90AA1

2.72e-0486014316GO:0097447
GeneOntologyCellularComponentgrowth cone

TENM2 NRXN1 CXCR4 LRP2 SLC2A13 CTTN PREX1 HSP90AA1

2.90e-042451438GO:0030426
GeneOntologyCellularComponentsite of polarized growth

TENM2 NRXN1 CXCR4 LRP2 SLC2A13 CTTN PREX1 HSP90AA1

3.59e-042531438GO:0030427
GeneOntologyCellularComponentchloride channel complex

GABRB1 GABRD GABRG2 GABRG3

6.26e-04571434GO:0034707
GeneOntologyCellularComponentprotein complex involved in cell adhesion

ITGAM ITGAX ITGB4 NRXN1

7.14e-04591434GO:0098636
GeneOntologyCellularComponentnuclear DNA-directed RNA polymerase complex

ERCC3 POLR3H POLR3B POLR1B TAF2

1.08e-031131435GO:0055029
GeneOntologyCellularComponentmonoatomic ion channel complex

GABRB1 GABRD GABRG2 GABRG3 PORCN GRIA4 KCNMA1 CTTN CATSPERG

1.20e-033781439GO:0034702
GeneOntologyCellularComponentDNA-directed RNA polymerase complex

ERCC3 POLR3H POLR3B POLR1B TAF2

1.22e-031161435GO:0000428
GeneOntologyCellularComponentendocytic vesicle

DPP4 ITSN1 GRIA4 CEMIP NRXN1 CLTC LRP2 CTTN HSP90AA1

1.33e-033841439GO:0030139
GeneOntologyCellularComponentintegrin complex

ITGAM ITGAX ITGB4

1.34e-03321433GO:0008305
GeneOntologyCellularComponentRNA polymerase complex

ERCC3 POLR3H POLR3B POLR1B TAF2

1.37e-031191435GO:0030880
GeneOntologyCellularComponentdense core granule membrane

VPS13C ACTN1

2.02e-03101432GO:0032127
GeneOntologyCellularComponenttransferase complex, transferring phosphorus-containing groups

ERCC3 POLR3H INSRR EXT2 CHUK POLR3B POLR1B TAF2

2.19e-033351438GO:0061695
GeneOntologyCellularComponentlate endosome

VPS13C NTRK1 MON1A KIDINS220 MVB12A CXCR4 ZFYVE26 SORL1

2.77e-033481438GO:0005770
GeneOntologyCellularComponentplasma membrane signaling receptor complex

ERBB3 INSRR PORCN GRIA4 ITGAM ITGAX ITGB4 CHUK

2.87e-033501438GO:0098802
GeneOntologyCellularComponentbasal plasma membrane

ERBB3 CNNM2 ITGB4 SLC22A8 OTOF PTPRQ SLC27A5 HSP90AA1

3.07e-033541438GO:0009925
GeneOntologyCellularComponentaxonal growth cone

NRXN1 LRP2 HSP90AA1

3.61e-03451433GO:0044295
DomainSyndecan

NRXN3 NRXN1 NRXN2

1.44e-0571413PF01034
DomainSyndecan/Neurexin_dom

NRXN3 NRXN1 NRXN2

1.44e-0571413IPR027789
DomainGABAA/Glycine_rcpt

GABRB1 GABRD GABRG2 GABRG3

2.47e-05231414IPR006028
DomainEFh

ITSN1 CAPSL CAPS ACTN1 HPCA SLC25A12 HPCAL1 TESC

2.69e-051581418SM00054
DomainVWFA

COL6A6 VWA8 ITGAM ITGAX ITGB4 HMCN1

3.64e-05821416PS50234
DomainVWA

COL6A6 VWA8 ITGAM ITGAX ITGB4 HMCN1

4.17e-05841416SM00327
DomainTyr_kinase_cat_dom

ERBB3 FLT3 NTRK1 INSRR TEC TXK

5.42e-05881416IPR020635
DomainTyrKc

ERBB3 FLT3 NTRK1 INSRR TEC TXK

5.42e-05881416SM00219
DomainEF_Hand_1_Ca_BS

ITSN1 CAPSL CAPS ACTN1 HPCA SLC25A12 HPCAL1 TESC

5.56e-051751418IPR018247
DomainPROTEIN_KINASE_TYR

ERBB3 FLT3 NTRK1 INSRR TEC TXK

9.36e-05971416PS00109
DomainTyr_kinase_AS

ERBB3 FLT3 NTRK1 INSRR TEC TXK

9.36e-05971416IPR008266
DomainVWF_A

COL6A6 VWA8 ITGAM ITGAX ITGB4 HMCN1

1.05e-04991416IPR002035
DomainNeurexin-like

NRXN3 NRXN1 NRXN2

1.44e-04141413IPR003585
Domain4.1m

NRXN3 NRXN1 NRXN2

1.44e-04141413SM00294
DomainEF-hand_1

CAPSL CAPS ACTN1 HPCA SLC25A12 HPCAL1 TESC

1.57e-041521417PF00036
DomainEF_HAND_1

ITSN1 CAPSL CAPS ACTN1 HPCA SLC25A12 HPCAL1 TESC

1.62e-042041418PS00018
DomainEGF-like_CS

SELE ITGB4 TENM2 NRXN3 HMCN1 NRXN1 NRXN2 LRP2 SORL1

1.67e-042611419IPR013032
Domain-

POLR3B POLR1B

1.69e-04314122.40.270.10
DomainRNA_pol_RPB2_OB-fold

POLR3B POLR1B

1.69e-0431412IPR014724
DomainRNA_pol_bsu_CS

POLR3B POLR1B

1.69e-0431412IPR007121
DomainDNA-dir_RNA_pol_su2_6

POLR3B POLR1B

1.69e-0431412IPR007120
DomainRNA_pol_Rpb2_7

POLR3B POLR1B

1.69e-0431412PF04560
DomainRNA_pol_Rpb2_2

POLR3B POLR1B

1.69e-0431412PF04561
DomainRNA_pol_Rpb2_5

POLR3B POLR1B

1.69e-0431412PF04567
DomainRNA_pol_Rpb2_1

POLR3B POLR1B

1.69e-0431412PF04563
DomainRNA_pol_Rpb2_3

POLR3B POLR1B

1.69e-0431412PF04565
DomainRNA_pol_Rpb2_5

POLR3B POLR1B

1.69e-0431412IPR007647
DomainRNA_pol_Rpb2_3

POLR3B POLR1B

1.69e-0431412IPR007645
DomainRNA_pol_bsu_protrusion

POLR3B POLR1B

1.69e-0431412IPR007644
DomainRNA_pol_Rpb2_2

POLR3B POLR1B

1.69e-0431412IPR007642
DomainRNA_pol_Rpb2_7

POLR3B POLR1B

1.69e-0431412IPR007641
DomainGABBAg_rcpt

GABRG2 GABRG3

1.69e-0431412IPR005437
Domain-

POLR3B POLR1B

1.69e-04314122.40.50.150
DomainRNA_POL_BETA

POLR3B POLR1B

1.69e-0431412PS01166
Domain-

POLR3B POLR1B

1.69e-04314123.90.1110.10
DomainDNA-dir_RNA_pol_su2

POLR3B POLR1B

1.69e-0431412IPR015712
DomainRNA_pol_Rpb2_6

POLR3B POLR1B

1.69e-0431412PF00562
DomainEGF_2

SELE ITGB4 TENM2 NRXN3 HMCN1 NRXN1 NRXN2 LRP2 SORL1

1.87e-042651419PS01186
DomainG8_domain

CEMIP2 CEMIP

3.36e-0441412IPR019316
DomainG8

CEMIP2 CEMIP

3.36e-0441412PS51484
DomainG8

CEMIP2 CEMIP

3.36e-0441412SM01225
DomainG8

CEMIP2 CEMIP

3.36e-0441412PF10162
DomainNeurotransmitter_ion_chnl_CS

GABRB1 GABRD GABRG2 GABRG3

3.65e-04451414IPR018000
DomainEF_HAND_2

ITSN1 CAPSL CAPS ACTN1 HPCA SLC25A12 HPCAL1 TESC

3.75e-042311418PS50222
DomainEF_hand_dom

ITSN1 CAPSL CAPS ACTN1 HPCA SLC25A12 HPCAL1 TESC

3.86e-042321418IPR002048
DomainEGF

SELE NRXN3 HMCN1 NRXN1 NRXN2 LRP2

3.90e-041261416PF00008
DomainNeur_chan_memb

GABRB1 GABRD GABRG2 GABRG3

3.97e-04461414PF02932
DomainPSI

SEMA4D ITGB4 SEMA3D SLC2A13

3.97e-04461414SM00423
DomainEGF

SELE TENM2 NRXN3 HMCN1 NRXN1 NRXN2 LRP2 SORL1

4.20e-042351418SM00181
DomainEGF_3

SELE TENM2 NRXN3 HMCN1 NRXN1 NRXN2 LRP2 SORL1

4.20e-042351418PS50026
DomainNeurotrans-gated_channel_TM

GABRB1 GABRD GABRG2 GABRG3

4.32e-04471414IPR006029
Domain-

GABRB1 GABRD GABRG2 GABRG3

4.32e-044714142.70.170.10
DomainNeur_chan_LBD

GABRB1 GABRD GABRG2 GABRG3

4.32e-04471414PF02931
DomainNEUROTR_ION_CHANNEL

GABRB1 GABRD GABRG2 GABRG3

4.32e-04471414PS00236
DomainNeur_channel

GABRB1 GABRD GABRG2 GABRG3

4.32e-04471414IPR006201
DomainNeur_chan_lig-bd

GABRB1 GABRD GABRG2 GABRG3

4.32e-04471414IPR006202
DomainPkinase_Tyr

ERBB3 FLT3 NTRK1 INSRR TEC TXK

4.42e-041291416PF07714
DomainFG_GAP

ITGAM ITGAX ITFG1

5.84e-04221413PS51470
DomainEGF-like_dom

SELE TENM2 NRXN3 HMCN1 NRXN1 NRXN2 LRP2 SORL1

6.15e-042491418IPR000742
DomainSer-Thr/Tyr_kinase_cat_dom

ERBB3 FLT3 NTRK1 INSRR TEC TXK

6.32e-041381416IPR001245
DomainEGF_1

SELE ITGB4 TENM2 NRXN3 HMCN1 NRXN1 NRXN2 LRP2

7.19e-042551418PS00022
DomainFG-GAP

ITGAM ITGAX ITFG1

7.59e-04241413PF01839
DomainFG-GAP

ITGAM ITGAX ITFG1

7.59e-04241413IPR013517
DomainCP2

GRHL2 GRHL3

8.32e-0461412PF04516
DomainCP2

GRHL2 GRHL3

8.32e-0461412IPR007604
DomainVWA

COL6A6 VWA8 ITGAM ITGAX

8.43e-04561414PF00092
DomainRecep_L_domain

ERBB3 INSRR

1.16e-0371412PF01030
DomainFurin-like

ERBB3 INSRR

1.16e-0371412PF00757
DomainRcpt_L-dom

ERBB3 INSRR

1.16e-0371412IPR000494
DomainFurin-like_Cys-rich_dom

ERBB3 INSRR

1.16e-0371412IPR006211
Domain-

ERBB3 INSRR

1.16e-03714123.80.20.20
DomainEF-hand-dom_pair

ITSN1 CAPSL CAPS ACTN1 HPCA SLC25A12 HPCAL1 TESC

1.53e-032871418IPR011992
DomainPectin_lyase_fold/virulence

CEMIP2 CEMIP

1.54e-0381412IPR011050
DomainLAM_G_DOMAIN

NRXN3 NRXN1 NRXN2

2.93e-03381413PS50025
DomainIntegrin_alpha

ITGAM ITGAX

2.98e-03111412PF00357
DomainTyr_kinase_rcpt_2_CS

NTRK1 INSRR

2.98e-03111412IPR002011
Domain-

TENM2 LRP2 SORL1

3.16e-033914132.120.10.30
DomainLaminin_G_2

NRXN3 NRXN1 NRXN2

3.39e-03401413PF02210
DomainRECEPTOR_TYR_KIN_II

NTRK1 INSRR

3.55e-03121412PS00239
Domain-

ITSN1 CAPSL ACTN1 HPCA SLC25A12 HPCAL1 TESC

3.71e-0326114171.10.238.10
DomainRecoverin

HPCA HPCAL1

4.18e-03131412IPR028846
DomainPSI

SEMA4D ITGB4 SEMA3D

4.45e-03441413IPR016201
DomainLamG

NRXN3 NRXN1 NRXN2

4.45e-03441413SM00282
Domain-

SEMA4D FLT3 NTRK1 INSRR ITGB4 SEMA3D IGSF22 HMCN1 NFATC1 RBPJ MYBPC1 SORL1

4.48e-03663141122.60.40.10
DomainLdl_recept_b

LRP2 SORL1

4.85e-03141412PF00058
DomainLDLRB

LRP2 SORL1

4.85e-03141412PS51120
DomainWH2

JMY WASF1

4.85e-03141412SM00246
Domain6-blade_b-propeller_TolB-like

TENM2 LRP2 SORL1

5.04e-03461413IPR011042
DomainLY

LRP2 SORL1

5.57e-03151412SM00135
DomainLDLR_classB_rpt

LRP2 SORL1

5.57e-03151412IPR000033
DomainChemokine_rcpt

CCR9 CXCR4

6.34e-03161412IPR000355
DomainIntegrin_alpha_C_CS

ITGAM ITGAX

6.34e-03161412IPR018184
DomainASX_HYDROXYL

NRXN3 HMCN1 NRXN1 LRP2

6.98e-031001414PS00010
DomainIg-like_fold

SEMA4D FLT3 NTRK1 INSRR ITGB4 SEMA3D IGSF22 HMCN1 NFATC1 RBPJ MYBPC1 SORL1

7.28e-0370614112IPR013783
Domainp53-like_TF_DNA-bd

NFATC1 NRK RBPJ

7.49e-03531413IPR008967
PathwayREACTOME_RHOBTB2_GTPASE_CYCLE

ACTN1 HNRNPCL3 RHOBTB2 HSP90AA1

3.64e-05251084MM15606
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

GABRB1 GABRG2 GABRG3 ERBB3 FLT3 COL6A6 NTRK1 RICTOR TEC KIDINS220 SHC2 CLTC WASF1 HSP90AA1

5.37e-0553210814M27870
PathwayWP_TNFALPHA_SIGNALING

SELE APAF1 CREBBP MADD CHUK HSP90AA1

7.35e-05921086M39662
PathwayWP_GABA_RECEPTOR_SIGNALING

GABRB1 GABRD GABRG2 GABRG3

8.74e-05311084M39369
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

GABRB1 GABRD GABRG2 CYP3A4 GRIA4 RICTOR NRXN3 SLC25A12 NRXN1 NRXN2 CTTN

1.16e-0436710811M48346
Pubmed

Conditional Knockout of Neurexins Alters the Contribution of Calcium Channel Subtypes to Presynaptic Ca2+ Influx.

NRXN3 NRXN1 NRXN2

7.40e-083147338891114
Pubmed

Alternative Splicing of Presynaptic Neurexins Differentially Controls Postsynaptic NMDA and AMPA Receptor Responses.

NRXN3 NRXN1 NRXN2

7.40e-083147331005376
Pubmed

Analysis of the human neurexin genes: alternative splicing and the generation of protein diversity.

NRXN3 NRXN1 NRXN2

7.40e-083147311944992
Pubmed

Alternative splicing of neurexins 1-3 is modulated by neuroinflammation in the prefrontal cortex of a murine model of multiple sclerosis.

NRXN3 NRXN1 NRXN2

7.40e-083147333058888
Pubmed

Important contribution of alpha-neurexins to Ca2+-triggered exocytosis of secretory granules.

NRXN3 NRXN1 NRXN2

7.40e-083147317035546
Pubmed

Neurexins: three genes and 1001 products.

NRXN3 NRXN1 NRXN2

7.40e-08314739448462
Pubmed

Deletion of α-neurexin II results in autism-related behaviors in mice.

NRXN3 NRXN1 NRXN2

7.40e-083147325423136
Pubmed

The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice.

NRXN3 NRXN1 NRXN2

7.40e-083147330858964
Pubmed

Structure and evolution of neurexin genes: insight into the mechanism of alternative splicing.

NRXN3 NRXN1 NRXN2

7.40e-083147312036300
Pubmed

Neurexin gene family variants as risk factors for autism spectrum disorder.

NRXN3 NRXN1 NRXN2

7.40e-083147329045040
Pubmed

Structural and functional characterization of the IgSF21-neurexin2α complex and its related signaling pathways in the regulation of inhibitory synapse organization.

NRXN3 NRXN1 NRXN2

7.40e-083147338571813
Pubmed

Deletion of β-Neurexins in Mice Alters the Distribution of Dense-Core Vesicles in Presynapses of Hippocampal and Cerebellar Neurons.

NRXN3 NRXN1 NRXN2

7.40e-083147335173587
Pubmed

alpha-Neurexins are required for efficient transmitter release and synaptic homeostasis at the mouse neuromuscular junction.

NRXN3 NRXN1 NRXN2

7.40e-083147316406382
Pubmed

Regulated Dynamic Trafficking of Neurexins Inside and Outside of Synaptic Terminals.

NRXN3 NRXN1 NRXN2

7.40e-083147326446217
Pubmed

Endogenous β-neurexins on axons and within synapses show regulated dynamic behavior.

NRXN3 NRXN1 NRXN2

7.40e-083147334133920
Pubmed

Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex.

NRXN3 NRXN1 NRXN2

7.40e-083147328013231
Pubmed

Ketamine Restores Thalamic-Prefrontal Cortex Functional Connectivity in a Mouse Model of Neurodevelopmental Disorder-Associated 2p16.3 Deletion.

NRXN3 NRXN1 NRXN2

7.40e-083147331812984
Pubmed

β-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling.

NRXN3 NRXN1 NRXN2

7.40e-083147326213384
Pubmed

Neurexins are differentially expressed in the embryonic nervous system of mice.

NRXN3 NRXN1 NRXN2

7.40e-08314737722633
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SYT3 ITSN1 MATR3 UBR4 MSANTD2 GRIA4 CCDC177 TENM2 OPA1 NRXN1 GPR158 CLTC KCNMA1 EML1 BUB3 CTTN WASF1 HSP90AA1

1.48e-079631471828671696
Pubmed

CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins.

NRXN3 NRXN1 NRXN2

2.95e-07414738786425
Pubmed

Neurexins regulate presynaptic GABAB-receptors at central synapses.

NRXN3 NRXN1 NRXN2

2.95e-074147333888718
Pubmed

Neurexins cluster Ca2+ channels within the presynaptic active zone.

NRXN3 NRXN1 NRXN2

2.95e-074147332134527
Pubmed

Deorphanizing FAM19A proteins as pan-neurexin ligands with an unusual biosynthetic binding mechanism.

NRXN3 NRXN1 NRXN2

2.95e-074147332706374
Pubmed

Deletion of alpha-neurexins does not cause a major impairment of axonal pathfinding or synapse formation.

NRXN3 NRXN1 NRXN2

2.95e-074147317347997
Pubmed

Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins.

NRXN3 NRXN1 NRXN2

2.95e-074147335385735
Pubmed

Postsynaptic N-methyl-D-aspartate receptor function requires alpha-neurexins.

NRXN3 NRXN1 NRXN2

2.95e-074147314983056
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

GABRB1 GABRG2 VWA8 UBR4 GRIA4 RICTOR TENM2 OPA1 MADD EIF3CL HPCA NRXN1 SUGP2 GPR158 HPCAL1 CLTC CTTN WASF1 HSP90AA1

3.72e-0711391471936417873
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

GABRD SEMA4D ERBB3 SMC1A ITSN1 UBR4 ACTN1 CREBBP MADD CHUK POLR3B OTOF DROSHA CLTC LRP2 CTTN PADI2 YME1L1 PREX1 HSP90AA1

5.30e-0712851472035914814
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

GABRG2 SYT3 ITSN1 MATR3 ACTN1 GTPBP1 CCDC177 OPA1 JMY MADD EIF3CL HNRNPCL3 HPCA KIDINS220 SLC25A12 SUGP2 NRXN2 CLTC CTTN WASF1 HSP90AA1

6.95e-0714311472137142655
Pubmed

Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions.

NRXN3 NRXN1 NRXN2

7.35e-075147336709330
Pubmed

Acetylcholinesterase-transgenic mice display embryonic modulations in spinal cord choline acetyltransferase and neurexin Ibeta gene expression followed by late-onset neuromotor deterioration.

NRXN3 NRXN1 NRXN2

7.35e-07514739223334
Pubmed

Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins.

NRXN3 NRXN1 NRXN2

7.35e-075147328472659
Pubmed

Trans-synaptic interaction of GluRdelta2 and Neurexin through Cbln1 mediates synapse formation in the cerebellum.

NRXN3 NRXN1 NRXN2

7.35e-075147320537373
Pubmed

Neuroligins and neurexins link synaptic function to cognitive disease.

NRXN3 NRXN1 NRXN2

7.35e-075147318923512
Pubmed

GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality.

GABRB1 GABRD GABRG2 GABRG3

8.95e-0718147418985723
Pubmed

Presynaptic α2δ-2 Calcium Channel Subunits Regulate Postsynaptic GABAA Receptor Abundance and Axonal Wiring.

NRXN3 NRXN1 NRXN2

1.47e-066147330683685
Pubmed

Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.

NRXN3 NRXN1 NRXN2

1.47e-066147312827191
Pubmed

Structures, alternative splicing, and neurexin binding of multiple neuroligins.

NRXN3 NRXN1 NRXN2

1.47e-06614738576240
Pubmed

The protein tyrosine kinase family of the human genome.

ERBB3 FLT3 NTRK1 INSRR TEC TXK

1.49e-0683147611114734
Pubmed

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method.

DPP4 ERBB3 ITSN1 EIF3CL NRXN1 KCNMA1

3.09e-0694147625201988
Pubmed

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.

GABRB1 MCM8 VWA8 ITSN1 ACTN1 TTC1 CHUK EML1 CTTN HSP90AA1

3.63e-063631471025036637
Pubmed

Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways.

NRXN3 NRXN1 NRXN2

4.08e-068147330871858
Pubmed

Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit.

NRXN3 NRXN1 NRXN2

4.08e-068147337591863
Pubmed

NCOA6 differentially regulates the expression of the CYP2C9 and CYP3A4 genes.

CYP3A4 MED1 HNF4A

4.08e-068147321292004
Pubmed

Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation.

SMC1A MED1 CXCR4 LRP2

4.26e-0626147428087629
Pubmed

Molecular self-avoidance in synaptic neurexin complexes.

NRXN3 NRXN1 NRXN2

6.10e-069147334919427
Pubmed

PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor.

NRXN3 NRXN1 NRXN2

6.10e-06914739707552
Pubmed

The ATM cofactor ATMIN protects against oxidative stress and accumulation of DNA damage in the aging brain.

SMC1A ITGAM ITGAX

8.69e-0610147320889973
Pubmed

Identification of Ca2+-dependent binding partners for the neuronal calcium sensor protein neurocalcin delta: interaction with actin, clathrin and tubulin.

HPCA HPCAL1 CLTC

8.69e-0610147311964161
Pubmed

TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson's disease.

VPS13C NTRK1 CTSC OPA1 HSP90AA1

9.85e-0667147534644545
Pubmed

A high-resolution radiation hybrid map of the proximal portion of mouse chromosome 5.

GABRB1 TEC TXK SEMA3D

1.14e-0533147410843805
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

GABRG2 PCDHGA2 ITSN1 MATR3 UBR4 GRIA4 ACTN1 HNRNPCL3 CHUK HPCA NRXN3 SLC25A12 NRXN1 HPCAL1 CLTC CTTN PREX1 HSP90AA1 MYBPC1

1.15e-0514421471935575683
Pubmed

SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins.

NRXN3 NRXN1 NRXN2

1.19e-0511147332973045
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

ERCC3 VWA8 SMC1A MATR3 MED1 OPA1 KIDINS220 SLC25A12 NRXN1 SUGP2 NRXN2 DROSHA CLTC BUB3 CATSPERG HSP90AA1

1.49e-0510821471638697112
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

ERCC3 SMC1A MATR3 UBR4 RICTOR ACTN1 CREBBP POLR3B SLC25A12 UBN1 SUGP2 CLTC PPP1R37 POLR1B TAF2 BUB3 YME1L1 HSP90AA1

1.75e-0513531471829467282
Pubmed

Association of ITGAX and ITGAM gene polymorphisms with susceptibility to IgA nephropathy.

ITGAM ITGAX

1.77e-052147231227791
Pubmed

Neurexin-3 subsynaptic densities are spatially distinct from Neurexin-1 and essential for excitatory synapse nanoscale organization in the hippocampus.

NRXN3 NRXN1

1.77e-052147237543682
Pubmed

Potent peptide agonists for human melanocortin 3 and 4 receptors derived from enzymatic cleavages of human beta-MSH(5-22) by dipeptidyl peptidase I and dipeptidyl peptidase IV.

DPP4 CTSC

1.77e-052147215985311
Pubmed

Notch signaling regulates CXCR4 expression and the migration of mesenchymal stem cells.

CXCR4 RBPJ

1.77e-052147223474530
Pubmed

GABA(A)R plasticity during pregnancy: relevance to postpartum depression.

GABRD GABRG2

1.77e-052147218667149
Pubmed

Leukocyte integrins.

ITGAM ITGAX

1.77e-05214728573344
Pubmed

Mutations in NRXN1 and NRXN2 in a patient with early-onset epileptic encephalopathy and respiratory depression.

NRXN1 NRXN2

1.77e-052147230709877
Pubmed

Dipeptidyl Peptidase-4 from Cancer-associated Fibroblasts Stimulates the Proliferation of Scirrhous-type Gastric Cancer Cells.

DPP4 CXCR4

1.77e-052147234969760
Pubmed

Increased expression of CXCR4 and integrin alphaM in hypoxia-preconditioned cells contributes to improved cell retention and angiogenic potency.

ITGAM CXCR4

1.77e-052147219415696
Pubmed

Altered expressions of CXCR4 and CD26 on T-helper lymphocytes in hereditary hemorrhagic telangiectasia.

DPP4 CXCR4

1.77e-052147234906163
Pubmed

Two novel GABAA receptor subunits exist in distinct neuronal subpopulations.

GABRD GABRG2

1.77e-05214722561970
Pubmed

E-selectin mediated adhesion and migration of endothelial colony forming cells is enhanced by SDF-1α/CXCR4.

SELE CXCR4

1.77e-052147223565284
Pubmed

Identification of new OPA1 cleavage site reveals that short isoforms regulate mitochondrial fusion.

OPA1 YME1L1

1.77e-052147233237841
Pubmed

HNF4α is a novel regulator of intestinal glucose-dependent insulinotropic polypeptide.

HNF4A GIP

1.77e-052147230862908
Pubmed

The delta subunit of the GABAA receptor is necessary for the GPT2-promoted breast cancer metastasis.

GABRD GPT2

1.77e-052147236923530
Pubmed

Human Txk: genomic organization, structure and contiguous physical linkage with the Tec gene.

TEC TXK

1.77e-05214728632917
Pubmed

Mitochondrial Optic Atrophy (OPA) 1 Processing Is Altered in Response to Neonatal Hypoxic-Ischemic Brain Injury.

OPA1 YME1L1

1.77e-052147226393574
Pubmed

CREB-binding protein is a transcriptional coactivator for hepatocyte nuclear factor-4 and enhances apolipoprotein gene expression.

HNF4A CREBBP

1.77e-052147210085149
Pubmed

Deletion of the complement phagocytic receptors CR3 and CR4 does not alter susceptibility to experimental cerebral malaria.

ITGAM ITGAX

1.77e-052147222882618
Pubmed

Female-specific decreases in alcohol binge-like drinking resulting from GABAA receptor delta-subunit knockdown in the VTA.

GABRD GABRG2

1.77e-052147231147611
Pubmed

Silencing of spontaneous activity at α4β1/3δ GABAA receptors in hippocampal granule cells reveals different ligand pharmacology.

GABRB1 GABRD

1.77e-052147232484592
Pubmed

Functional association between CBP and HNF4 in trans-activation.

HNF4A CREBBP

1.77e-05214729434765
Pubmed

Locus category based analysis of a large genome-wide association study of rheumatoid arthritis.

TEC TXK

1.77e-052147220639398
Pubmed

Down-Regulation of CYP3A4 by the KCa1.1 Inhibition Is Responsible for Overcoming Resistance to Doxorubicin in Cancer Spheroid Models.

CYP3A4 KCNMA1

1.77e-052147237958656
Pubmed

SOX13 dependent PAX8 expression promotes the proliferation of gastric carcinoma cells.

SOX13 PAX8

1.77e-052147231353958
Pubmed

The coactivator PGC-1 is involved in the regulation of the liver carnitine palmitoyltransferase I gene expression by cAMP in combination with HNF4 alpha and cAMP-response element-binding protein (CREB).

CPT1A HNF4A

1.77e-052147212107181
Pubmed

Postsynaptic clustering of gamma-aminobutyric acid type A receptors by the gamma3 subunit in vivo.

GABRG2 GABRG3

1.77e-052147210536013
Pubmed

Altered crosstalk in the dipeptidyl peptidase-4-incretin-immune system in type 1 diabetes: A hypothesis generating pilot study.

DPP4 GIP

1.77e-052147226434625
Pubmed

MS-275, a novel histone deacetylase inhibitor with selectivity against HDAC1, induces degradation of FLT3 via inhibition of chaperone function of heat shock protein 90 in AML cells.

FLT3 HSP90AA1

1.77e-052147218394702
Pubmed

NGF/TrkA-mediated Kidins220/ARMS signaling activated in the allergic airway challenge in mice.

NTRK1 KIDINS220

1.77e-052147220934630
Pubmed

Neurexin I alpha is a major alpha-latrotoxin receptor that cooperates in alpha-latrotoxin action.

NRXN3 NRXN1

1.77e-05214729430716
Pubmed

BCR activated CLL B cells use both CR3 (CD11b/CD18) and CR4 (CD11c/CD18) for adhesion while CR4 has a dominant role in migration towards SDF-1.

ITGAM ITGAX

1.77e-052147234283878
Pubmed

Angiotensin II Stimulation of DPP4 Activity Regulates Megalin in the Proximal Tubules.

DPP4 LRP2

1.77e-052147227213360
Pubmed

The role and regulation of TMEM2 (transmembrane protein 2) in HYBID (hyaluronan (HA)-binding protein involved in HA depolymerization/ KIAA1199/CEMIP)-mediated HA depolymerization in human skin fibroblasts.

CEMIP2 CEMIP

1.77e-052147230241936
Pubmed

Association of a polymorphism in the NRXN3 gene with the degree of smoking in schizophrenia: a preliminary study.

NRXN3 NRXN1

1.77e-052147219658047
Pubmed

Lipopolysaccharide-induced maturation of bone marrow-derived dendritic cells is regulated by notch signaling through the up-regulation of CXCR4.

CXCR4 RBPJ

1.77e-052147219357083
Pubmed

PEA3 activates CXCR4 transcription in MDA-MB-231 and MCF7 breast cancer cells.

ETV4 CXCR4

1.77e-052147221831961
Pubmed

Concurrent Overexpression of Two Hyaluronidases, KIAA1199 and TMEM2, Strongly Predicts Shorter Survival After Resection in Pancreatic Ductal Adenocarcinoma.

CEMIP2 CEMIP

1.77e-052147236395406
Pubmed

Relation between CXCR-4 expression, Flt3 mutations, and unfavorable prognosis of adult acute myeloid leukemia.

FLT3 CXCR4

1.77e-052147215054042
Pubmed

Heterozygous deletion of α-neurexin I or α-neurexin II results in behaviors relevant to autism and schizophrenia.

NRXN1 NRXN2

1.77e-052147226595880
Pubmed

Impact of CXCR4 inhibition on FLT3-ITD-positive human AML blasts.

FLT3 CXCR4

1.77e-052147220035824
Pubmed

Expression and regulation of recently discovered hyaluronidases, HYBID and TMEM2, in chondrocytes from knee osteoarthritic cartilage.

CEMIP2 CEMIP

1.77e-052147236241903
Pubmed

Neurocalcin family: a novel calcium-binding protein abundant in bovine central nervous system.

HPCA HPCAL1

1.77e-05214728387172
Pubmed

Integrin CD11c contributes to monocyte adhesion with CD11b in a differential manner and requires Src family kinase activity.

ITGAM ITGAX

1.77e-052147218541300
InteractionMET interactions

DPP4 ERBB3 SMC1A UBR4 RICTOR TEC ITGB4 TXK SHC2 GPR158 CTTN HSP90AA1

1.04e-0629014212int:MET
Cytoband4p12

GABRB1 TEC TXK

3.52e-052014734p12
GeneFamilyGamma-aminobutyric acid type A receptor subunits

GABRB1 GABRD GABRG2 GABRG3

3.47e-06191024563
GeneFamilyADAM metallopeptidase domain containing|CD molecules

SELE DPP4 SEMA4D FLT3 CCR9 ITGAM ITGAX ITGB4 RHAG CXCR4

7.72e-0539410210471
GeneFamilyEF-hand domain containing

ITSN1 CAPSL CAPS HPCA SLC25A12 HPCAL1 TESC

2.42e-042191027863
GeneFamilyFibronectin type III domain containing

INSRR ITGB4 IGSF22 PTPRQ MYBPC1 SORL1

2.92e-041601026555
GeneFamilyRNA polymerase subunits

POLR3H POLR3B POLR1B

5.73e-04291023726
GeneFamilyReceptor Tyrosine Kinases|CD molecules

FLT3 NTRK1 INSRR

1.48e-03401023321
GeneFamilyWiskott-Aldrich Syndrome protein family

JMY WASF1

3.59e-0316102214
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

GABRG2 PDE1A COL6A6 GRIA4 RICTOR CSMD2 TENM2 HNRNPCL3 CEMIP PPP2R2B NRXN3 SLC25A12 NRXN1 SUGP2 NRXN2 GPR158 PKIA KCNMA1 CATSPERG WASF1

2.84e-06110614420M39071
CoexpressionGRESHOCK_CANCER_COPY_NUMBER_UP

FLT3 ERCC3 NTRK1 ETV4 EXT2 TEC CREBBP PAX8 CLTC HSP90AA1

1.26e-0532314410M9150
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-41|World / Primary Cells by Cluster

GABRG2 SEMA4D PDE1A ITSN1 HPCA PPP2R2B NRXN1 CXCR4 HSP90AA1

1.93e-081961479dee0984cd63a1a2fdebb4421af48ab566a5b684e
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

GABRB1 GABRG2 HPCA PPP2R2B NRXN3 KIDINS220 NRXN1 NRXN2 PKIA

2.01e-0819714794961f66606f08e399508fd6cabca588e7ab406a8
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal|10w / Sample Type, Dataset, Time_group, and Cell type.

SCRT2 GRIA4 TENM2 PPP2R2B NRXN3 KIDINS220 NRXN1 NRXN2 PKIA

2.29e-082001479979258173b82f37aeaaedd53b4a527da1dbe1b80
ToppCellRA-16._Neuronal|RA / Chamber and Cluster_Paper

ERBB3 CAPS ITGB4 RHAG PPP2R2B NRXN3 NRXN1 GPT2

1.56e-0718014785842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DPP4 ERBB3 HNF4A GRHL2 NRXN3 GPR158 LRP2 SORL1

2.36e-071901478625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERBB3 HNF4A GRHL2 NRXN3 GPR158 LRP2 TESC SORL1

2.55e-071921478b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area|World / Primary Cells by Cluster

GABRG3 PDE1A ITSN1 PPP2R2B KIDINS220 NRXN1 KCNMA1 WASF1

3.10e-07197147879b9e7f2e8e33b3c547f716be5667156c48b0dfc
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area-33|World / Primary Cells by Cluster

GABRG3 PDE1A ITSN1 PPP2R2B KIDINS220 NRXN1 KCNMA1 WASF1

3.10e-071971478d20f29088e9afd8a960d6f680075c380e550f8a7
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG2 GABRG3 TENM2 NRXN3 NRXN1 GPR158 KCNMA1 SLC2A13

3.23e-0719814786d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellLPS-antiTNF-Stromal_mesenchymal-Fibroblasts-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMEM104 MON1A F8 CLSPN PADI2 LRRC75A MYBPC1

7.17e-071511477f13a117ae26ae525da4f3e837d8f204d00dc6ee3
ToppCellControl-Lymphocytic_NKT-T_cells-T-cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP4 SEMA4D ISG20 TEC CXCR4 TESC SORL1

2.15e-061781477910f8bea19d335455aba24e6a07b4834b709db5d
ToppCellControl-Lymphocytic_NKT-T_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP4 SEMA4D ISG20 TEC CXCR4 TESC SORL1

2.23e-061791477d892d9496f1c33e23312092591eb2e968e736f7d
ToppCellLPS_only-Lymphocytic_NKT-T_cells-T-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP4 SEMA4D TEC NFATC1 CXCR4 PREX1 SORL1

2.32e-061801477dcef253f2e97e4436b1b04e8a06a53ff6e64522c
ToppCellRA-16._Neuronal|World / Chamber and Cluster_Paper

ERBB3 CAPS ITGB4 RHAG PPP2R2B NRXN3 NRXN1

2.41e-0618114777d22a43f887e0747f0cb87ba364ff27905ee6eec
ToppCellLPS_only-Lymphocytic_NKT-T_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP4 SEMA4D TEC NFATC1 CXCR4 PREX1 SORL1

2.41e-061811477a4347ae554e6dcf03c7001a2b69332b377c7c034
ToppCellRA-17._Lymphocyte|World / Chamber and Cluster_Paper

DPP4 SEMA4D CEMIP2 TXK PPP2R2B CXCR4 SORL1

2.59e-0618314776397f684a50346fc42cccb5afbe10350f4b2d9b0
ToppCellCerebellum-Neuronal|Cerebellum / BrainAtlas - Mouse McCarroll V32

GABRG2 FLT3 MATR3 HPCA SHC2 GPR158 SLC2A13

2.99e-06187147761b9d6eb131a674598aa8409d7fa909c8765442d
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERBB3 TEC HNF4A GRHL2 LRP2 GPT2 SORL1

3.20e-0618914775d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCellCOVID-19-Heart-T_cell|Heart / Disease (COVID-19 only), tissue and cell type

SEMA4D RHAG TXK PPP2R2B NRXN3 CXCR4 SORL1

3.32e-061901477e6c3a6e01fef6c5b49f72661d4fb0414ba9046bf
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A CPT1A TENM2 KIDINS220 TESC SLC2A13 SORL1

3.43e-061911477297bc79adc5fef211497819b4861b52cd26ac754
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A CPT1A TENM2 KIDINS220 TESC SLC2A13 SORL1

3.43e-061911477e1ec165ba6578cefd88895e7e183190e79f733a4
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DPP4 ISG20 MB21D2 CXCR4 PKIA LRRC75A SORL1

3.43e-0619114779c747f8cc1cdce45e839b661d782e1e8cfb79578
ToppCellwk_15-18-Endothelial-Lymph_endothelial-Intermediate_lymphatic_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DPP4 PDE1A ITGB4 F8 NRXN3 SHC2 NFATC1

3.43e-061911477d25ac3206fe205a100cfee26431ff32c14c1938f
ToppCellCOVID-19-kidney-Myeloid|COVID-19 / Disease (COVID-19 only), tissue and cell type

ITGAM ITGAX CXCR4 RBPJ PREX1 HSP90AA1 SORL1

3.55e-0619214770b9d22a222f1201e375f8e55cace9ef939febae4
ToppCellControl-B_memory-6|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SCRT2 ITGAX NRXN1 KCNMA1 TESC PREX1

3.57e-0612414763e987915026f503e8d072a837b6e7a34252e5c63
ToppCellControl-Myeloid-Monocyte-derived_macrophages|Control / group, cell type (main and fine annotations)

CTSC ITSN1 ITGAX MB21D2 RBPJ KCNMA1 PREX1

3.68e-061931477a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERBB3 HNF4A GRHL2 LRP2 TESC GPT2 SORL1

3.68e-0619314774b8202fcfe639a73f69a13f48fc3601ade256346
ToppCellRA-08._Macrophage|RA / Chamber and Cluster_Paper

ITGAM ITGAX CEMIP2 TXK RBPJ KCNMA1 TEC

3.80e-061941477ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCellLA-08._Macrophage|LA / Chamber and Cluster_Paper

ITGAM CEMIP2 TXK RBPJ KCNMA1 PREX1 TEC

3.94e-0619514775e1d5bdb8874091f5a2b1d0a8cc9008165718a97
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG2 ACTN1 TENM2 NRXN1 KCNMA1 WASF1 SORL1

3.94e-0619514772e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG2 CSMD2 TENM2 CEMIP HPCA SLC2A13 SORL1

3.94e-061951477787e95fb59c40bba784544b662fac37606ae1427
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG2 GABRG3 TENM2 NRXN3 NRXN1 GPR158 SLC2A13

4.07e-061961477676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellILEUM-non-inflamed-(6)_ILC-(6)_ILC1|(6)_ILC / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CEBPD CTSC ISG20 ITGAX CEMIP2 TXK TESC

4.07e-0619614778a3a63129adfbe58558af91336f81d397c291ed0
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Deep_Layer-37|World / Primary Cells by Cluster

GABRG2 GABRG3 PDE1A TENM2 HPCA NRXN1 KCNMA1

4.21e-06197147700d756bc0231e1b3b88430214338c1059cb11106
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-Neurons|GW23 / Sample Type, Dataset, Time_group, and Cell type.

GABRB1 DPP4 PDE1A PPP2R2B HPCAL1 EML1 BUB3

4.35e-06198147790ebefc9ba8dc2a81471e5693384f5ce56f06298
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG2 GABRG3 TENM2 NRXN3 NRXN1 KCNMA1 SLC2A13

4.35e-061981477c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG2 GABRG3 NRXN3 NRXN1 GPR158 KCNMA1 SLC2A13

4.35e-0619814774ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellControl-Control-Myeloid-Neutrophil|Control / Disease, condition lineage and cell class

PARD3B ACTN1 ITGAX UBN1 PADI2 PREX1 SORL1

4.65e-06200147795c41f147a1594d49e73cb56d86d301c3115ce20
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Cortical_neuron|10w / Sample Type, Dataset, Time_group, and Cell type.

GRIA4 TENM2 PPP2R2B KIDINS220 NRXN1 NRXN2 PKIA

4.65e-06200147768c90376e2779434e4ad8dc6dd3b44baa700e2f4
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

MATR3 TENM2 NRXN3 NRXN1 CXCR4 PKIA HSP90AA1

4.65e-062001477ac0e023dbb383bbc46c5cc525431778be8f7ef46
ToppCellsevere-Myeloid-Neutrophils_4|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CEBPD ACTN1 ITGAM ITGAX PADI2 PREX1 SORL1

4.65e-062001477b665f36dcf3c9d3981ee96f2973512f751612542
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PDE1A PCDHGA2 ETV4 CSMD2 TENM2 NRK MYBPC1

4.65e-06200147729054cf55e88e1ac81a562d8dd9af9b7c749321d
ToppCellfacs-Marrow-B-cells-24m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRG2 CCR9 ITGAX MVB12A NRXN2 PADI2

9.50e-0614714769d7e965fe61bd7b31e09c4b2129a5a98c36f4811
ToppCellfacs-Marrow-B-cells-24m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRG2 CCR9 ITGAX MVB12A NRXN2 PADI2

9.50e-06147147638552953ff65a0fc20bee6ef57dc5885306ad18b
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

GABRG2 GABRG3 GRIA4 CSMD2 NRXN1 GPR158

9.88e-061481476d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4D ACTN1 ITGAM CXCR4 ZFYVE26 SORL1

1.07e-0515014766e806a028c0519489151c181d9907e05289e27e0
ToppCellRV-16._Neuronal|RV / Chamber and Cluster_Paper

ERBB3 ITGB4 RHAG PPP2R2B NRXN3 NRXN1

1.19e-051531476bed8bbf5c5cbfbf46a816066da472c3fdddecb5d
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

GABRG3 CSMD2 TENM2 NRXN3 NRXN1 GPR158

1.49e-0515914765335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGAM ITGAX TXK HPCAL1 PADI2 PREX1

1.71e-0516314762e1c1193c04620cc187b1567dfba025beef1e4e1
ToppCellfacs-MAT-Fat-3m-Myeloid-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT3 CTSC ITGAM ITGAX RBPJ PREX1

1.77e-0516414761250876abd7311f86730e5b9c03c3610cc2ff6d3
ToppCellfacs-MAT-Fat-3m-Myeloid|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT3 CTSC ITGAM ITGAX RBPJ PREX1

1.77e-051641476fa0d77b648cde5e42b9394e877168c80de238bde
ToppCellLV-16._Neuronal|World / Chamber and Cluster_Paper

ERBB3 ITGB4 RHAG PPP2R2B NRXN3 NRXN1

1.83e-0516514766ed52cb756d21addf46c7f6c457458b01339fe04
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_bronchial_vessel-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SELE MATR3 ITGB4 PAX8 TESC SLC27A5

1.90e-051661476a697460dfe72e08fbf7d8e734a16b7dd2c6d86f9
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGAM ITGAX MB21D2 RBPJ KCNMA1 PREX1

2.03e-05168147661a5435b27b01ff1a509ea463a6af220c5d2c9b3
ToppCellLA-16._Neuronal|World / Chamber and Cluster_Paper

ERBB3 ITGB4 RHAG PPP2R2B NRXN3 NRXN1

2.03e-0516814762fd1fd2a16ac1c5eb028f93cc3a2477c7747693e
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGAM ITGAX MB21D2 RBPJ KCNMA1 PREX1

2.03e-05168147626fce414439ccd204e3acb41f2b4f75072df5a26
ToppCellLA-16._Neuronal|LA / Chamber and Cluster_Paper

ERBB3 ITGB4 RHAG PPP2R2B NRXN3 NRXN1

2.03e-051681476c55bbfbde8bb954f1cb9af82007bdd1f8070fee3
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DPP4 SEMA4D CCR9 ISG20 HNF4A CXCR4

2.10e-05169147620b17f1d6d845213479ade09ea0c7ecc277a73c6
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLT3 ITGAX RHOBTB2 RBPJ CLSPN GPT2

2.10e-0516914763e40ae0b23a962e0f15908872dec63f51c5b8b83
ToppCellLV-16._Neuronal|LV / Chamber and Cluster_Paper

ERBB3 ITGB4 RHAG PPP2R2B NRXN3 NRXN1

2.10e-051691476a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCellLPS-IL1RA-Lymphocytic_NKT-T_cells-T-cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP4 SEMA4D TEC CXCR4 TESC SORL1

2.24e-051711476539ea88acc6f948efdeae8b69e5c5ffaee29f1d9
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_THEMIS_PLA2G7|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPP4 FLT3 ISG20 CPT1A TEC TXK

2.32e-0517214761d086e00cd549459d70e1d3b468d5ab6379f3bee
ToppCellLPS-IL1RA-Lymphocytic_NKT-T_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP4 SEMA4D TEC CXCR4 TESC SORL1

2.32e-0517214760fc692be845d4225ff8b63bf9195724fc8510c2c
ToppCelldroplet-Thymus-nan-3m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT3 ITGAX NRXN1 NRXN2 OTOF PKIA

2.39e-05173147663f03abca84ae021ff34ff34537838aa8a1ccd11
ToppCellLPS-antiTNF-Lymphocytic_NKT-iNKT/MAIT|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA4D NTRK1 TEC ITGAX TESC PREX1

2.47e-05174147661aa89b56ebda0eba1ba675d5f036992967f670f
ToppCellControl-CD4+_T_activated|Control / Disease group and Cell class

DPP4 TXK IGSF22 NFATC1 OTOF PAX8

2.47e-0517414762b683e81b315ad22555314433aed5681feb48da8
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CNNM2 TEC ITGAM ITGAX TXK WDSUB1

2.47e-051741476ccc79febfcf588d8294ffc712338be96de8a5033
ToppCellLPS-antiTNF-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA4D NTRK1 TEC ITGAX TESC PREX1

2.55e-05175147698cb577df466700e72d1bbc6689205ccf2e7fcba
ToppCellfacs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR9 ITSN1 ITGAX MVB12A NRXN2 PADI2

2.64e-05176147674f851a398c7562dd713bc0d8d488c0037243112
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT-T_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP4 SEMA4D TEC CXCR4 TESC SORL1

2.64e-051761476bb41e9478373726eb460af764de0277b2d09928e
ToppCellfacs-Marrow-T_cells-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR9 ITSN1 ITGAX MVB12A NRXN2 PADI2

2.64e-05176147631b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Neutrophil|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CEBPD SYT3 ITGAX CXCR4 PREX1 SORL1

2.72e-051771476ed44b1bf2ffae97f94e944d1b6060d5163eba6a6
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA4D NTRK1 TEC ITGAX TESC PREX1

2.81e-051781476f914092c20130207193f97c6044ae61a9a440a86
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT-iNKT/MAIT|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA4D NTRK1 TEC ITGAX TESC PREX1

2.81e-0517814767905621f5b2aa55324c5592d1d2fef763a5fa41f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ERICH1 PDE1A CPT1A NRK TESC PADI2

2.81e-051781476dfed0fbf7a73b8a9e00178ec58dc4592b271c344
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PARD3B ISG20 TXK SHC2 CXCR4 SORL1

2.81e-05178147673936c2e7e8855b4ab65cad425686513dba331a3
ToppCellLPS_only-Lymphocytic_NKT-iNKT/MAIT|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NTRK1 TEC ITGAX TESC PREX1 SORL1

2.90e-051791476de3ddc1264e43727be50d69b81cc84a3c91812a2
ToppCell3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Microfold_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

INSRR ETV4 ITGAM HNF4A TESC LRRC75A

2.90e-051791476c7d7a66fca6a41de0af3cc2b75a29a54456842cd
ToppCellLPS_only-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NTRK1 TEC ITGAX TESC PREX1 SORL1

2.90e-051791476def981e97e3ff9019910c9af3861ca0d08eb0d0f
ToppCellfacs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT3 CCR9 ITGAX MVB12A NRXN2 PADI2

2.99e-051801476bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ERICH1 PDE1A VWA8 SLC25A12 NRK PADI2

2.99e-0518014769e09b3dfe344b5d50520711513d389865d73a861
ToppCellfacs-Marrow-B-cells-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT3 CCR9 ITGAX MVB12A NRXN2 PADI2

2.99e-05180147682965ed1b72a1873c24dd4553d39681596057316
ToppCellControl-Myeloid-Dendritic_cells|Control / group, cell type (main and fine annotations)

FLT3 ITGAX MB21D2 RBPJ KCNMA1 PADI2

2.99e-05180147625ad95c3c30e3b82abe93bd77ba003f5c2241f7c
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SELE ACTN1 ITGB4 CEMIP2 NRXN3 HMCN1

3.08e-051811476cef034030e6b029a49ae56be37ea1fac1a5c350e
ToppCellfacs-Marrow-B-cells-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT3 CCR9 ITGAX MVB12A NRXN2 PADI2

3.08e-051811476782716b8b1d447d2bbe09a693fa5ed7ebeac0efb
ToppCellfacs-Marrow-B-cells-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT3 CCR9 ITGAX MVB12A NRXN2 PADI2

3.08e-051811476e2481291c236105774c53883e6f20da11941df9b
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-Treg|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NTRK1 ISG20 TEC ITGAM PKIA CCDC33

3.08e-0518114763754970d62eea1d2522b11d977eea4362f90d21e
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GABRB1 ERBB3 CSMD2 PPP2R2B NRXN1 PREX1

3.18e-051821476bfb725fff3d20066d8ac0a6ba2f88498fcbd876e
ToppCelldroplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB3 GRHL2 NRXN1 SHPK GPT2 CATSPERG

3.18e-0518214766fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCellRA-17._Lymphocyte|RA / Chamber and Cluster_Paper

DPP4 SEMA4D TXK CXCR4 PREX1 SORL1

3.18e-051821476257a7847917b6ea1d60608183d90300bfd028758
ToppCellControl-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA4D ISG20 TEC ITGAX TESC SORL1

3.28e-0518314762c5707ada3442eb7100a2a5f9438d5a2ac53a9e1
ToppCellIPF-Lymphoid-ILC_A|IPF / Disease state, Lineage and Cell class

CCR9 ISG20 CEMIP2 TXK PPP2R2B CXCR4

3.28e-05183147649bfeaae13eb236f61a5486ee75c39789936bb8a
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB3 CAPSL NRXN3 TESC PADI2 PREX1

3.28e-0518314767eaa6ef7c6cf848fd6489f97677f4406318da22f
ToppCellControl-Lymphocytic_NKT|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SEMA4D ISG20 TEC CXCR4 TESC SORL1

3.48e-05185147659d68e119f58b35bab36294758f6b2e25fd8f5c0
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DPP4 PDE1A ITGB4 F8 NRXN3 NFATC1

3.48e-051851476f9f48251bc33eb6bf2cff580d1a3207d21450aa0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HNF4A SLC22A8 HPCAL1 PAX8 LRP2 GPT2

3.59e-0518614765784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DPP4 ERBB3 GRHL2 GPR158 LRP2 TESC

3.59e-051861476bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE1A CNNM2 ACTN1 CSMD2 TENM2 KCNMA1

3.59e-051861476a95744b8649096bd7cfc3591a02841fa411085b3
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GABRB1 PDE1A SLC25A12 NRK SLC2A13 PADI2

3.70e-051871476b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCellhuman_hepatoblastoma-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

GABRB1 DPP4 ERBB3 PARD3B HNF4A GPT2

3.70e-051871476f3e37c18ac6471c7992609bbddfa4975571c815c
Drug3-isothujone

GABRB1 GABRD GABRG2 GABRG3 CYP3A4 YME1L1

2.90e-08301436CID000011027
Drug5 beta-pregnanediol

GABRB1 GABRD GABRG2 GABRG3 CYP3A4 HNF4A KCNMA1

9.73e-08601437CID000012547
Drugsevoflurane

GABRB1 GABRD GABRG2 GABRG3 CAPS NAGLU CHKB GPT2

3.32e-071051438CID000005206
Drugthymol

GABRB1 GABRD GABRG2 GABRG3 KCNMA1 GPT2

4.21e-07461436CID000006989
DrugAndrogen Antagonists

GABRB1 ERBB3 NTRK1 GRIA4 ACTN1 NRXN1 NRXN2

4.62e-07751437ctd:D000726
DrugIpratropium bromide [22254-24-6]; Up 200; 9.8uM; PC3; HT_HG-U133A

CNNM2 SMC1A ISG20 PPP2R2B NRXN3 SHC2 NFATC1 PAX8 CTTN CCDC33

4.93e-07197143105823_UP
DrugLinuron

GABRB1 ERBB3 CYP3A4 APAF1 GRIA4 ACTN1 NRXN1 NRXN2

1.51e-061281438ctd:D008044
Drugsodium linoleate

ERBB3 CYP3A4 CTSC MED1 CPT1A CHKB ITGAM ITGAX KCNMA1 LRP2 SLC27A5 SORL1

1.78e-0634214312CID000003931
DrugAC1L2FYN

GABRB1 GABRD GABRG2 GABRG3 KCNMA1

1.88e-06331435CID000071333
Drugdihydroxyaflavinine

GABRB1 GABRD GABRG2 GABRG3

3.33e-06171434CID000156857
DrugDichlorodiphenyl Dichloroethylene

GABRB1 ERBB3 CYP3A4 NTRK1 APAF1 GRIA4 ACTN1 CPT1A CREBBP NRXN1 NRXN2

3.41e-0630214311ctd:D003633
DrugDMCM

GABRB1 GABRD GABRG2 GABRG3 DMRTA1

3.87e-06381435CID000104999
Drugzaleplon

GABRB1 GABRD GABRG2 GABRG3 CYP3A4

4.42e-06391435CID000005719
Drugendrine

GABRB1 GABRD GABRG2 GABRG3 CYP3A4 SLC27A5 HSP90AA1

4.83e-061061437CID000003048
Drugfelbamate

GABRB1 GABRD GABRG2 GABRG3 CYP3A4 GRIA4

5.21e-06701436CID000003331
Drugprocymidone

GABRB1 ERBB3 CYP3A4 GRIA4 ACTN1 HNF4A NRXN1 NRXN2

6.29e-061551438ctd:C035988
Drugzolpidem

GABRB1 GABRD GABRG2 GABRG3 CYP3A4

7.24e-06431435CID000005732
Drugsitagliptin

DPP4 CYP3A4 CTSC GIP SLC22A8

8.12e-06441435CID004369359
Drugheptachlor epoxide

GABRB1 GABRD GABRG2 GABRG3 GRHL3

1.02e-05461435CID000013930
Druggabapentin

GABRB1 GABRD GABRG2 GABRG3 CYP3A4 GRIA4 SLC2A13 GPT2

1.19e-051691438CID000003446
Drugfenofibric acid

DPP4 CYP3A4 CPT1A SLC22A8 GPT2

1.39e-05491435CID000064929
Drugvigabatrin

GABRB1 GABRD GABRG2 GABRG3 CYP3A4

1.39e-05491435CID000005665
Drugmethohexital

GABRB1 GABRD GABRG2 GABRG3

1.44e-05241434CID000009034
Drugenzacamene

GABRB1 ERBB3 NTRK1 GRIA4 ACTN1 NRXN1 NRXN2

1.76e-051291437ctd:C038939
Drugmetformin

DPP4 INSRR EXT2 CPT1A CHKB HNF4A GIP SLC2A13 GPT2

1.83e-052351439CID000004091
Drugneostigmine

GABRB1 GABRD GABRG2 GABRG3 CYP3A4 NTRK1

1.84e-05871436CID000004456
Drugpicrotoxin

GABRB1 GABRD GABRG2 GABRG3 PORCN GRIA4 CXCR4 WASF1

1.95e-051811438CID000031304
Drugendosulfan

GABRB1 GABRD GABRG2 GABRG3 CYP3A4 GPT2

1.96e-05881436CID000003224
Drugtriazolam

GABRB1 GABRD GABRG2 GABRG3 CYP3A4

2.25e-05541435CID000005556
DrugX1043

DPP4 CTSC GIP

2.82e-05101433CID011235728
Drugoctylmethoxycinnamate

GABRB1 ERBB3 NTRK1 GRIA4 ACTN1 NRXN1 NRXN2

2.85e-051391437ctd:C118580
DrugDichlorodiphenyldichloroethane

ERBB3 CYP3A4 NTRK1 CREBBP

3.14e-05291434ctd:D003632
Drugflunitrazepam

GABRB1 GABRD GABRG2 GABRG3 CYP3A4

3.47e-05591435CID000003380
DrugPinacidil [85371-64-8]; Up 200; 16.4uM; MCF7; HT_HG-U133A

DPP4 FLT3 CCR9 APAF1 CREBBP NRXN1 CXCR4 KCNMA1

3.57e-0519714385456_UP
DrugAcetylsalicylsalicylic acid [530-75-6]; Up 200; 13.4uM; HL60; HG-U133A

VWA8 ITSN1 APAF1 ITGAM CXCR4 BUB3 WASF1 YME1L1

3.70e-0519814381377_UP
Drugsimvastatin

SELE CYP3A4 CCR9 HNF4A CHUK SLC22A8 CXCR4 LRP2 GPT2 HSP90AA1 SORL1

3.71e-0539014311CID000054454
DrugI vs

DPP4 EXT2 F8 OPA1 GIP KIDINS220 DROSHA

4.07e-051471437CID000444340
Drugcyclothiazide

GABRB1 GABRD GABRG2 GABRG3 GRIA4 KCNMA1

4.79e-051031436CID000002910
DrugCGS 8216

GABRB1 GABRD GABRG2 GABRG3

5.30e-05331434CID000104916
Drugtaxol

SEMA4D ERBB3 CYP3A4 APAF1 TEC ITGB4 CHUK ITFG1 NRK RBPJ TTC32 BUB3 HSP90AA1

5.44e-0556014313CID000004666
Drugpicrotoxinine

GABRB1 GABRD GABRG2 GABRG3 KCNMA1

5.56e-05651435CID000004816
Drugbutylparaben

GABRB1 ERBB3 NTRK1 GRIA4 ACTN1 NRXN1 NRXN2

6.19e-051571437ctd:C038091
Drugifosfamide

SEMA4D CYP3A4 NAGLU GRHL2 ITFG1

6.43e-05671435CID000003690
Drugvitamin D3

CYP3A4 CTSC APAF1 MED1 ITGAM ITGAX RHAG NFATC1 LRP2

6.61e-052771439CID000002735
Drugflurazepam

GABRB1 GABRD GABRG2 GABRG3

6.71e-05351434CID000003393
Drugsecobarbital

GABRB1 GABRD GABRG2 GABRG3

8.39e-05371434CID000005193
DrugMe-lex

GABRG2 GABRG3 CYP3A4

8.39e-05141433CID000004177
DrugDMAEMA

F8 OPA1 CLTC

8.39e-05141433CID000017869
Drugtetrachlorophenol

CYP3A4 NTRK1 TEC

8.39e-05141433CID000021013
DrugAC1L322F

DPP4 CTSC GIP

1.04e-04151433CID000133040
DrugGabrene

GABRB1 GABRD GABRG2 GABRG3

1.14e-04401434CID005361323
Druglapachenole

CYP3A4 CTSC

1.17e-0431432CID000174859
DrugHexobarbital

GABRG2 CYP3A4

1.17e-0431432ctd:D006591
Drug4-(dimethylamino)benzoic acid

F8 OPA1

1.17e-0431432CID000012092
Drugnesina

DPP4 GIP

1.17e-0431432CID016088021
Druggaboxadol

GABRB1 GABRD GABRG2 GABRG3

1.26e-04411434CID000003448
Drug3,6,9,12,15-pentaoxaheptadecan-1-ol

GABRG3 NTRK1 NFATC1 WDSUB1

1.26e-04411434CID000078058
Drugnimetazepam

GABRG2 GABRG3 CYP3A4

1.28e-04161433CID000004496
Drug3-hydroxy-3-methylglutaryl-CoA

CYP3A4 CPT1A CHKB HNF4A SLC22A8 KCNMA1 GPT2 SORL1

1.30e-042371438CID000000084
Drug17-isoprogesterone

GABRB1 GABRD GABRG2 GABRG3 DPP4 ERBB3 CYP3A4 PCDHGA2 APAF1 ETV4 GRIA4 ACTN1 ITGB4 CXCR4 KCNMA1 POLR1B SLC2A13 TAF2 HSP90AA1

1.36e-04117014319CID000004920
Drug5 beta-alphaxalone

GABRB1 GABRD GABRG2 GABRG3

1.39e-04421434CID000068930
Drugthioridazine hydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A

GABRD APAF1 ISG20 CREBBP CEMIP KIDINS220 CXCR4

1.41e-0417914375590_UP
Drugbis(tri-n-butyltin)oxide

GABRG3 SMC1A MATR3 APAF1 PORCN ISG20 ACTN1 HNF4A CREBBP NFATC1 CXCR4 POLR1B

1.54e-0453814312ctd:C005961
Drugzolpidem

GABRB1 GABRG2 CYP3A4

1.55e-04171433ctd:C049109
Drugcolchine

GABRB1 SELE GABRD GABRG2 GABRG3 ISG20 LRP2 GRHL3 GPT2 YME1L1

1.59e-0438314310CID000002833
Druglorazepam

GABRB1 GABRD GABRG2 GABRG3

1.67e-04441434CID000003958
Drugclonazepam

GABRB1 GABRD GABRG2 GABRG3 CYP3A4

1.69e-04821435CID000002802
Drugnevirapine

CYP3A4 CXCR4 KCNMA1 GPT2

1.82e-04451434CID000004463
Drugbuformin

DPP4 CPT1A CHKB

1.85e-04181433CID000002468
DrugAC1L3X9U

DPP4 ITGAM ITGAX

1.85e-04181433CID000096811
DrugMethoxychlor

GABRD CYP3A4 SMC1A ITSN1 INSRR MED1 ITGAM HPCAL1 CXCR4 KCNMA1 WASF1 HSP90AA1

1.86e-0454914312ctd:D008731
DrugAC1L1B1W

GABRB1 GABRD GABRG2 GABRG3 GRIA4

1.89e-04841435CID000001248
Drug17alpha-estradiol

GABRB1 SELE GABRD ERICH1 GABRG2 GABRG3 ERBB3 CEBPD CYP3A4 NTRK1 CCR9 ISG20 MED1 GIP CXCR4 KCNMA1 LRP2 TAF2 GPT2 SORL1

1.91e-04130314320CID000000450
Diseaserheumatoid arthritis

DPP4 ERBB3 FLT3 NTRK1 TEC GRHL2 MB21D2 NFATC1 RBPJ PADI2 PREX1 TEC

2.25e-0646214012EFO_0000685
DiseaseSchizophrenia

GABRB1 GABRD GABRG2 ERBB3 CNNM2 CYP3A4 NTRK1 GRIA4 CSMD2 ITGAM OPA1 SEMA3D NRXN3 NRXN1 NRXN2 LRP2

4.85e-0688314016C0036341
Diseasealcohol use disorder (implicated_via_orthology)

ERBB3 RIOX1 HNF4A CREBBP MADD RBPJ KCNMA1

4.23e-051951407DOID:1574 (implicated_via_orthology)
DiseaseAcute Promyelocytic Leukemia

FLT3 SMC1A ITGAM ITGAX

6.79e-05461404C0023487
Diseasecystathionine measurement

PARD3B TEC TEC

9.58e-05191403EFO_0010474
DiseaseFanconi syndrome (implicated_via_orthology)

HNF4A LRP2

1.33e-0441402DOID:1062 (implicated_via_orthology)
Diseasetyrosine-protein kinase TEC measurement

TEC TEC

1.33e-0441402EFO_0020830
Diseaseuric acid measurement

PDE1A CNNM2 NTRK1 INSRR HNF4A TENM2 CEMIP NRXN2 NFATC1 LRP2 SLC27A5

1.65e-0461014011EFO_0004761
DiseaseC-reactive protein measurement

SEMA4D CYP3A4 VPS13C CAPSL NAGLU RICTOR MON1A GTPBP1 HNF4A JMY MADD EIF3CL GIP PAX8 PPP1R37 POLR1B

2.01e-04120614016EFO_0004458
DiseaseAutistic Disorder

GABRB1 VWA8 NRXN3 SLC25A12 NRXN1 NRXN2 KCNMA1

2.58e-042611407C0004352
Diseasecolorectal adenocarcinoma (is_marker_for)

ERBB3 RICTOR HPCA

2.81e-04271403DOID:0050861 (is_marker_for)
DiseaseIntellectual Disability

NAGLU POLR3B NRXN1 NRXN2 RHOBTB2 LRP2 TAF2 GPT2 WASF1

2.96e-044471409C3714756
Diseasevisceral adipose tissue measurement

SEMA4D NAGLU PARD3B MON1A NRXN3 SLC22A8 NRXN1 GPR158 EML1

5.02e-044811409EFO_0004765
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

SMC1A CPT1A ITGAM HNF4A GPT2

6.97e-041471405DOID:9352 (biomarker_via_orthology)
Diseaseglycosyl-N-palmitoyl-sphingosine (d18:1/16:0) measurement

GABRB1 TXK

7.87e-0491402EFO_0800476
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

GABRD GABRG2

7.87e-0491402C3502809
Diseaseautism spectrum disorder (implicated_via_orthology)

CREBBP NRXN3 NRXN1 NRXN2 PREX1

8.10e-041521405DOID:0060041 (implicated_via_orthology)
Diseaseejection fraction measurement

GRIA4 HMCN1 GPR158

1.12e-03431403EFO_0005527
Diseaseforced expiratory volume, response to bronchodilator

GRIA4 RICTOR ITGAM ITGAX NRXN1 NRXN2 CTTN PREX1

1.33e-034451408EFO_0004314, GO_0097366
Diseaserheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement

FLT3 TEC GRHL2 RBPJ TEC

1.33e-031701405EFO_0000685, EFO_0007791, EFO_0007837
DiseaseAdenoid Cystic Carcinoma

SMC1A INSRR ITGB4 CREBBP

1.34e-031001404C0010606
Diseaselymphangioleiomyomatosis (is_marker_for)

RICTOR CPT1A

1.43e-03121402DOID:3319 (is_marker_for)
Diseaseacute myeloid leukemia (implicated_via_orthology)

FLT3 CREBBP

1.43e-03121402DOID:9119 (implicated_via_orthology)
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

GABRB1 PDE1A ERBB3 CNNM2 GRIA4 TENM2 CEMIP2 NRXN3 NRXN1 NRXN2 SORL1

1.57e-0380114011EFO_0003888, EFO_0007052, MONDO_0002491
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

GABRB1 GABRD PARD3B

1.64e-03491403DOID:0060037 (implicated_via_orthology)
DiseaseDiverticular Bleeding

GTPBP1 GPR158

1.68e-03131402C4505353
DiseaseFulminant Hepatic Failure with Cerebral Edema

GABRB1 GABRG2

1.68e-03131402C0751197
DiseaseHepatic Stupor

GABRB1 GABRG2

1.68e-03131402C0751198
Diseasehyperglycemia (is_marker_for)

ITGAM GIP

1.68e-03131402DOID:4195 (is_marker_for)
DiseaseDiverticular Diseases

GTPBP1 GPR158

1.68e-03131402C4317009
DiseaseHepatic Encephalopathy

GABRB1 GABRG2

1.68e-03131402C0019151
DiseaseHepatic Coma

GABRB1 GABRG2

1.68e-03131402C0019147
DiseaseSkin Abnormalities

APAF1 CHUK

1.68e-03131402C0037268
Disease5alpha-pregnan-3beta,20beta-diol monosulfate (1) measurement

CYP3A4 CAPSL

1.68e-03131402EFO_0800284
DiseaseTourette syndrome

FLT3 TENM2 POLR3B

1.74e-03501403EFO_0004895
DiseaseMalignant neoplasm of breast

ERBB3 ERCC3 SYT3 CYP3A4 UBR4 ETV4 CPT1A OTOF CXCR4 ZFYVE26 CLSPN HSP90AA1 SORL1

1.85e-03107414013C0006142
DiseaseMetabolic Bone Disorder

KCNMA1 LRP2

1.96e-03141402C0005944
DiseaseDrug habituation

GRIA4 TENM2 NRXN3 SLC2A13

2.23e-031151404C0013170
DiseaseDrug abuse

GRIA4 TENM2 NRXN3 SLC2A13

2.23e-031151404C0013146
DiseasePrescription Drug Abuse

GRIA4 TENM2 NRXN3 SLC2A13

2.23e-031151404C4316881
DiseaseSubstance-Related Disorders

GRIA4 TENM2 NRXN3 SLC2A13

2.23e-031151404C0236969
DiseaseDrug Use Disorders

GRIA4 TENM2 NRXN3 SLC2A13

2.23e-031151404C0013222
DiseaseDrug Dependence

GRIA4 TENM2 NRXN3 SLC2A13

2.23e-031151404C1510472
DiseaseSubstance Dependence

GRIA4 TENM2 NRXN3 SLC2A13

2.23e-031151404C0038580
DiseaseSubstance Use Disorders

GRIA4 TENM2 NRXN3 SLC2A13

2.23e-031151404C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

GRIA4 TENM2 NRXN3 SLC2A13

2.23e-031151404C0029231
DiseaseOsteopenia

KCNMA1 LRP2

2.25e-03151402C0029453
Diseaseglycerate measurement

CCR9 HMCN1

2.25e-03151402EFO_0021029
Diseasehepatic encephalopathy (biomarker_via_orthology)

GABRB1 GABRG2

2.25e-03151402DOID:13413 (biomarker_via_orthology)
DiseaseSubstance abuse problem

GRIA4 TENM2 NRXN3 SLC2A13

2.30e-031161404C0740858
DiseaseNeuralgia, Supraorbital

NTRK1 CXCR4

2.57e-03161402C0038870
DiseaseNeuralgia

NTRK1 CXCR4

2.57e-03161402C0027796
DiseaseNeuralgia, Atypical

NTRK1 CXCR4

2.57e-03161402C0234247
DiseaseNeuralgia, Stump

NTRK1 CXCR4

2.57e-03161402C0234249
DiseaseNeuralgia, Iliohypogastric Nerve

NTRK1 CXCR4

2.57e-03161402C0423712
DiseaseNeuralgia, Perineal

NTRK1 CXCR4

2.57e-03161402C0423711
DiseaseParoxysmal Nerve Pain

NTRK1 CXCR4

2.57e-03161402C0751373
DiseaseNerve Pain

NTRK1 CXCR4

2.57e-03161402C0751372
DiseaseNeuralgia, Ilioinguinal

NTRK1 CXCR4

2.57e-03161402C0751371
DiseaseNeuralgia, Vidian

NTRK1 CXCR4

2.57e-03161402C0042656
DiseaseIGA glomerulonephritis

ITGAM ITGAX SORL1

2.67e-03581403EFO_0004194
Diseasenarcolepsy-cataplexy syndrome

ERBB3 CTSC PREX1

2.80e-03591403MONDO_0016158
Diseasecolon cancer (is_marker_for)

RICTOR CHUK HSP90AA1

2.80e-03591403DOID:219 (is_marker_for)
DiseaseMultiple congenital anomalies

CHUK NRXN1

2.90e-03171402C0000772
Diseaselevel of Sterol ester (27:1/20:3) in blood serum

HNF4A NRXN1

3.63e-03191402OBA_2045199
DiseaseAlzheimer's disease (is_implicated_in)

NTRK1 PPP2R2B KCNMA1 SORL1

3.67e-031321404DOID:10652 (is_implicated_in)
DiseaseDermatitis, Allergic Contact

SELE CTSC ITGAM

4.01e-03671403C0162820
DiseaseHematochezia, response to radiation

ERICH1 GABRG3

4.02e-03201402GO_0009314, HP_0002573
Diseaseandrosterone glucuronide measurement

CYP3A4 SLC22A8

4.02e-03201402EFO_0800317
Diseaselymphocyte count

ERBB3 FLT3 CYP3A4 PCDHGA2 NTRK1 INSRR GRHL2 SEMA3D NRXN2 NFATC1 PAX8 CXCR4 POLR1B DMRTA1 PREX1

4.13e-03146414015EFO_0004587
Diseaseschizophrenia (implicated_via_orthology)

CNNM2 CTSC NRXN1

4.18e-03681403DOID:5419 (implicated_via_orthology)
DiseaseProfound Mental Retardation

NAGLU POLR3B NRXN1 TAF2

4.41e-031391404C0020796
DiseaseMental Retardation, Psychosocial

NAGLU POLR3B NRXN1 TAF2

4.41e-031391404C0025363
DiseaseMental deficiency

NAGLU POLR3B NRXN1 TAF2

4.41e-031391404C0917816
Diseaseforced expiratory volume

CYP3A4 PARD3B MED1 NRXN3 CXCR4 DROSHA KCNMA1 PREX1 HSP90AA1 MYBPC1

4.49e-0378914010EFO_0004314
Diseasesmoking cessation

CNNM2 POLR3H TENM2 NRXN3 NRXN1 KCNMA1

4.66e-033251406EFO_0004319

Protein segments in the cluster

PeptideGeneStartEntry
YEMGPEYSSNVELAS

GPT2

321

Q8TD30
SSSYDYEALDEAMSI

APAF1

356

O14727
YASNETMLTLFYEDS

CATSPERG

571

Q6ZRH7
STQEMYFYDGVSRDA

ERICH1

346

Q86X53
SLEELGYEYMDVGSD

ERBB3

1216

P21860
GYEYMDVGSDLSASL

ERBB3

1221

P21860
VNSDYETYMSADDLR

PPP2R2B

181

Q00005
ALDYMSFSTALYGES

ACTN1

876

P12814
MEGISIYTSDNYTEE

CXCR4

1

P61073
IYTSDNYTEEMGSGD

CXCR4

6

P61073
SMSYEGFNITFSEYD

CSMD2

1021

Q7Z408
YYSGVSASMNTDEEF

CAPS

251

Q13938
EDTALVLEYYSSTSM

CCDC33

486

Q8N5R6
LADVYRTYDADMTTS

AMBN

391

Q9NP70
YGLSEADMEASYATV

GTPBP1

106

O00178
VEGDMYESANSRDEY

CREBBP

636

Q92793
GYRSEDPDTSMDSYA

CPT1A

426

P50416
NDGTTLAIASSYMYE

BUB3

286

O43684
RYAEGTFISDYSIAM

GIP

51

P09681
NADSLMLVDFEYSSY

CHKB

256

Q9Y259
ASMSTIEFGYLDYAQ

CHKB

361

Q9Y259
GDTLVIASTDYSMYQ

CEMIP

436

Q8WUJ3
YLAAATTAVYEAMTA

NAGLU

326

P54802
FAYDSDVTGCASMYL

ETV4

266

P43268
YQELESDGSTMEDYS

MSANTD2

221

Q6P1R3
YASSAIAGMVAGSEY

PAX8

386

Q06710
ILTVTATDADEGYYA

PCDHGA2

261

Q9Y5H1
DMSGYTIYDTSTDRL

ISG20

101

Q96AZ6
ENVDMRDSYLGYSTE

ITGAX

396

P20702
SMYDLDGNGYISREE

HPCA

106

P84074
MTDVETTYADFIASG

PKIA

1

P61925
DTESFILAAMAYDRY

OR5I1

111

Q13606
LTISGTQAMDEADYY

IGLV3-1

91

P01715
LDYATGAIGSVYDMD

PARD3B

931

Q8TEW8
IGDFGMSRDIYSTDY

NTRK1

666

P04629
DSYTLAAMAYDRAVA

OR1A2

111

Q9Y585
TETDGDMLGYDLYSS

KIDINS220

431

Q9ULH0
MDYDDSSSSYSSLGD

MADD

626

Q8WXG6
MATTEDAQAAVDYYT

MATR3

441

P43243
NVYARGTDYDMDFTL

MB21D2

106

Q8IYB1
GVSNEMYTEYLSSAF

KCNMA1

596

Q12791
LYQMEDEAYSSLAEA

JMY

361

Q8N9B5
YSMLGTYSDEFGNLD

MCM8

746

Q9UJA3
EAYEDELDMGRSGSY

GPR158

681

Q5T848
AAEMYGSSFDLDYNL

HNRNPCL3

101

B7ZW38
LERYSEQMTYGISSE

CHUK

491

O15111
MESTSLDDVLYRYAS

LRRC75A

86

Q8NAA5
STSAESDMYYGQSLL

KIAA1109

1161

Q2LD37
GYETTSSVLSFIMYE

CYP3A4

306

P08684
DMADYSAALDPAYTT

HNF4A

11

P41235
YTSALTYDGVLVMAE

GRIA4

296

P48058
MSDGSYSPDYSLAAV

PDE1A

481

P54750
SMYDLDGNGYISRSE

HPCAL1

106

P37235
TMKSAEEEHYGYASS

NFATC1

36

O95644
TGYTQEDYTMLGSDD

NRXN2

411

Q9P2S2
CEREATVLSYDGSMY

NRXN2

726

Q9P2S2
GYTQEDYTMLGSDDF

NRXN3

366

Q9Y4C0
TSTEAMTYDEASAYC

SELE

26

P16581
NYSVMDICDYDESSG

DPP4

321

P27487
SVSDPKATMYSYDSA

GABRB1

386

P18505
QECMLDLESYGYSSE

GABRD

176

O14764
AAEMYGSSFDLDYNL

HNRNPCL4

101

P0DMR1
YYSSFVNMERDLASG

F8

551

P00451
VMSLDYDSVSDRIYF

LRP2

2421

P98164
TTTGYTQEDYTMLGS

NRXN1

396

Q9ULB1
AGYEIVLYISMSDSD

PADI2

196

Q9Y2J8
GATEFYLLASMSYDR

OR6C4

106

Q8NGE1
DAQSGEDYDSFLMYS

ITGB4

1336

P16144
SMVSSATYGGSDDYI

RICTOR

1411

Q6R327
DSIYEASSLYGISAM

MVB12A

201

Q96EY5
TLAFVFDVTGSMYDD

HMCN1

41

Q96RW7
MYDVYIAAETSAGTG

PTPRQ

411

Q9UMZ3
ASALFDMIEYYESAT

PPP1R37

151

O75864
VDDTTEEQGYGMAYT

PORCN

421

Q9H237
DMYSEVLDVLSDYDA

OPA1

266

O60313
YSRYGSEEALSSTMG

MON1A

266

Q86VX9
ALEEGNYFEMSTYST

FLT3

291

P36888
YSSVYDSISMETLSD

EIF3CL

796

B5ME19
VAMQDGDPTEYYSTA

IGSF22

491

Q8N9C0
DSYLLPTTDMYDNGS

GRHL3

161

Q8TE85
ASVGAEEYMYDQTSS

GRHL2

231

Q6ISB3
FMNYYAGVSASIDTD

CAPSL

181

Q8WWF8
AMYDDESAIDFSAYI

CEBPD

51

P49716
SAGDYVVMTIYFELS

GABRG3

236

Q99928
EFIAMYTYESSEQGD

ITSN1

1006

Q15811
DYAFSGMIRDSSYLS

DMRTA1

471

Q5VZB9
DYGSESTSSMEDYVN

CCR9

16

P51686
SGDYVVMSVYFDLSR

GABRG2

256

P18507
TATTYMEYETLTLGD

CTSC

186

P53634
ASTDYSMYQAEEFTL

CEMIP2

436

Q9UHN6
IGDFGMTRDVYETDY

INSRR

1131

P14616
NAEMFGSTYCDYTIE

GARIN6

226

Q8NEG0
SMRVATGLYEAYEAE

CCDC177

126

Q9NQR7
MEDGFSSYSSLYDTS

EML1

1

O00423
SGADDTVYMEYHSSR

ERCC3

751

P19447
ELLRYYTSASGDEMV

HSP90AA1

461

P07900
YTSASGDEMVSLKDY

HSP90AA1

466

P07900
DSMYAEDSEGNNLSY

DRC3

251

Q9H069
ATGFAYYSLAMGVEE

SLC22A8

336

Q8TCC7
SSGSIDYDEYNIMKD

COL6A6

816

A6NMZ7
ASGTECYITSDMFYV

MED1

96

Q15648
EDVSREAGYDSTYGM

OTOF

1466

Q9HC10
IDQSADSEGDYMSYQ

NRK

1356

Q7Z2Y5
YYSATILQMSGVEDD

SLC2A13

346

Q96QE2
YLDMDSYPEAAAAAV

SYT3

161

Q9BQG1
YYSSDPMDQVGDSTV

DROSHA

421

Q9NRR4
DSYGENYLSFTLTME

SORL1

1756

Q92673
FRGEAAVTDSYSMDA

SCRT2

96

Q9NQ03
SDFGMARYVLDDQYT

TEC

506

P42680
EAYVEVAAYASMSIF

TAF2

311

Q6P1X5
EYLYTGMFTSSPDLD

RHOBTB2

556

Q9BYZ6
QEDSGHDTMSYRDSY

PREX1

1156

Q8TCU6
SYDAAGTIHDYVVAM

SHPK

171

Q9UHJ6
AMESSSGEEYYVASD

TENM2

2356

Q9NT68
YETEEGAHDLYMDTG

POLR3H

131

Q9Y535
AHSYTSVMVDGELYS

SEMA4D

161

Q92854
SVMVDGELYSGTSYN

SEMA4D

166

Q92854
DSDMNDAYLGYAAAI

ITGAM

396

P11215
TYYQGLFSTADLDSM

RIOX1

236

Q9H6W3
FASVMTDEYLYSGTA

SEMA3D

191

O95025
LQYASTEVDGERYMT

SLC25A12

21

O75746
DSYIKADDPSSYMEV

CLTC

1126

Q00610
MYDSDSDGRITLEEY

TESC

121

Q96BS2
TVADSDESYMEKSLY

CLSPN

106

Q9HAW4
EASAFSYYGVMALTA

CNNM2

706

Q9H8M5
ERMVEDYLASGYQDS

ZNF561

26

Q8N587
HSVADGEMYRYSEDE

SOX13

591

Q9UN79
GDTDMTDYVAYVAKD

SHC2

256

P98077
SGDVYYNTGDVLAMD

SLC27A5

526

Q9Y2P5
GLAYATEAVYESAEA

CTTN

461

Q14247
MLNDSDDDVIYGSDY

TMEM181

576

Q9P2C4
AEMYDDVHSDGRYSL

SUGP2

51

Q8IX01
NELLMAISDSDYYTD

EXT2

131

Q93063
MAGEITETGELYSSY

TMEM104

1

Q8NE00
EESAYYSDLFAMIGT

RHAG

201

Q02094
SMVYSEEGAEDRTFA

SMC1A

81

Q14683
LYPDATEGEAYADMS

VPS13C

1676

Q709C8
ADYMASTIGFYSESG

RNF121

201

Q9H920
VAVMSYSGYDIEDAL

POLR3B

741

Q9NW08
RVDFYEAMDDYTSAI

TTC32

71

Q5I0X7
ISTDKAEYTFYEGMG

RBPJ

331

Q06330
YYASGSEFDEMFVGV

YME1L1

401

Q96TA2
MTRYVLDDEYVSSFG

TXK

411

P42681
IDMGYGYDESDSFID

UBN1

126

Q9NPG3
TYVDHMDGSYSLSAL

WASF1

241

Q92558
VIASDGYSYEKEAME

WDSUB1

421

Q8N9V3
GDYDGDSQMDVLLTY

ITFG1

106

Q8TB96
AIVAVISYTGYDMED

POLR1B

741

Q9H9Y6
QMSEYDAATYERFSG

VWA8

1631

A3KMH1
SAGYIYTQLMEEASS

UBR4

2066

Q5T4S7
DYIEAESSYSRALEM

TTC1

131

Q99614
AAAGMVFYSISDVTD

ZFYVE26

916

Q68DK2
MTDDSEYYVTAGDEK

MYBPC1

316

Q00872