Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

CDHR2 CDH23 PCDH15 GPD2 FAT4 DSG2 PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 FAT3 PITPNM1 OIT3 HMCN1 SUSD1 PCDHGA12 PRF1 LRP2 EML1 PCDHGA8 PCDH9

2.46e-0774919224GO:0005509
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO7A MYO10 DNAH6 KIF26B DNAH2 GPR88 DNAH12 MYO15A

1.87e-051181928GO:0003774
GeneOntologyMolecularFunctionhydrolase activity, hydrolyzing O-glycosyl compounds

HPSE2 MGAM2 SI MANEA LCTL TREH GUSB

6.20e-051031927GO:0004553
GeneOntologyMolecularFunctionhydrolase activity, acting on glycosyl bonds

HPSE2 MGAM2 SI MANEA LCTL TREH GUSB SMPD1

7.79e-051441928GO:0016798
GeneOntologyMolecularFunctionsemaphorin receptor activity

PLXND1 PLXNA1 PLXNA3

1.81e-04121923GO:0017154
GeneOntologyMolecularFunctionglucosidase activity

MGAM2 SI LCTL

3.66e-04151923GO:0015926
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

CDHR2 CDH23 PCDH15 IGSF9 FAT4 DSG2 PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 FAT3 HMCN1 PCDHGA12 PCDHGA8 PCDH9

1.64e-1318719218GO:0007156
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

CDHR2 CDH23 PCDH15 IGSF9 FAT4 DSG2 PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 FAT3 CLDN23 HMCN1 PCDHGA12 TENM1 PCDHGA8 PCDH9

1.49e-1131319220GO:0098742
GeneOntologyBiologicalProcesscell-cell adhesion

CDHR2 MYO10 IRAK1 CDH23 NFASC PCDH15 IGSF9 COL14A1 SEMA4D FAT4 DSG2 PCDHGB1 PCDHGA9 KIF26B PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 FAT3 PKP4 FNDC3A CLDN23 SLFN12L HMCN1 PCDHGA12 TENM1 TNR PCDHGA8 PCDH9

7.23e-08107719230GO:0098609
GeneOntologyBiologicalProcessneuromuscular process controlling balance

MYO7A CDH23 PCDH15 CWH43 CNTNAP1 GPR88 TNR

5.77e-06741927GO:0050885
GeneOntologyBiologicalProcesspositive regulation of 3'-UTR-mediated mRNA stabilization

LARP4B TENT4B ELAVL4

1.56e-0561923GO:1905870
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

MYO7A CDH23 NFASC PLXND1 TTC3 LHX9 NEDD4 NFIX PCDH15 IGSF9 PLXNA1 PLXNA3 SEMA4D STXBP5 FAT3 CNTNAP1 ZIC2 LRP2 ELAVL4 TNR

2.35e-0574819220GO:0048667
GeneOntologyBiologicalProcessregulation of 3'-UTR-mediated mRNA stabilization

LARP4B TENT4B ELAVL4

2.70e-0571923GO:1905868
GeneOntologyBiologicalProcesscell morphogenesis

RHOJ MYO7A MYO10 CDH23 NFASC PLXND1 TTC3 LHX9 NEDD4 NFIX PCDH15 IGSF9 SCFD1 PLXNA1 PLXNA3 SEMA4D STXBP5 FAT3 CNTNAP1 SPAG6 STRIP1 ZIC2 FAM171A1 LRP2 ELAVL4 TNR

4.75e-05119419226GO:0000902
GeneOntologyBiologicalProcessresponse to cocaine

PGR NOS1 DRD3 OPRK1 ELAVL4 SMPD1

5.21e-05711926GO:0042220
GeneOntologyBiologicalProcessneuron projection development

MYO7A CDH23 NFASC PLXND1 PTBP1 TTC3 LHX9 NEDD4 UBE2V2 NFIX PCDH15 IGSF9 OLIG1 PLXNA1 PLXNA3 SEMA4D FAT4 STXBP5 FAT3 CNTNAP1 SPAG6 ZIC2 PTPN5 CSPG4 LRP2 ELAVL4 TNR

6.16e-05128519227GO:0031175
GeneOntologyBiologicalProcessequilibrioception

MYO7A CDH23 PCDH15

6.40e-0591923GO:0050957
GeneOntologyBiologicalProcesslocomotory behavior

CDH23 PCDH15 BAHCC1 DRD3 CWH43 HIPK2 GPR88 OPRK1 ELAVL4 MYO15A TNR

7.53e-0528419211GO:0007626
GeneOntologyBiologicalProcessolfactory nerve formation

PLXNA1 PLXNA3

8.62e-0521922GO:0021628
GeneOntologyBiologicalProcesstransport across blood-brain barrier

SLC22A8 ABCC2 SLC2A4 SLC5A1 SLC19A1 LRP2

1.63e-04871926GO:0150104
GeneOntologyBiologicalProcessresponse to alkaloid

PGR NOS1 DRD3 TMEM38B OPRK1 ELAVL4 SMPD1

1.72e-041251927GO:0043279
GeneOntologyBiologicalProcessvascular transport

SLC22A8 ABCC2 SLC2A4 SLC5A1 SLC19A1 LRP2

1.73e-04881926GO:0010232
GeneOntologyBiologicalProcess3'-UTR-mediated mRNA stabilization

PTBP1 LARP4B TENT4B ELAVL4

1.88e-04311924GO:0070935
GeneOntologyBiologicalProcessneuron development

MYO7A CDH23 NFASC PLXND1 PTBP1 TTC3 LHX9 NEDD4 UBE2V2 NFIX PCDH15 IGSF9 OLIG1 PLXNA1 PLXNA3 SEMA4D FAT4 STXBP5 FAT3 CNTNAP1 SPAG6 ZIC2 PTPN5 CSPG4 TENM1 LRP2 ELAVL4 TNR

2.17e-04146319228GO:0048666
GeneOntologyBiologicalProcessolfactory nerve morphogenesis

PLXNA1 PLXNA3

2.57e-0431922GO:0021627
GeneOntologyBiologicalProcessfolate import across plasma membrane

SLC19A1 LRP2

2.57e-0431922GO:1904447
GeneOntologyBiologicalProcessneuromuscular process

MYO7A CDH23 PCDH15 DRD3 CWH43 CNTNAP1 HIPK2 GPR88 TNR

2.68e-042251929GO:0050905
GeneOntologyCellularComponentcluster of actin-based cell projections

DOCK4 PLB1 MYO7A CDHR2 CDH23 PCDH15 ABCC2 SI SLC5A1 LCTL TREH SLC19A1 LRP2 MYO15A

2.30e-0822319414GO:0098862
GeneOntologyCellularComponentsemaphorin receptor complex

PLXND1 PLXNA1 PLXNA3 SEMA4D

4.82e-06131944GO:0002116
GeneOntologyCellularComponentbrush border

PLB1 CDHR2 ABCC2 SI SLC5A1 LCTL TREH SLC19A1 LRP2

1.27e-051521949GO:0005903
GeneOntologyCellularComponentapical part of cell

PLB1 MYO7A CDHR2 CDH23 IFIT5 SLC22A8 ABCC2 ABCG8 FAT4 DRD3 DSG2 SI TLR9 SLC5A1 SLC19A1 CSPG4 LRP2

3.98e-0559219417GO:0045177
GeneOntologyCellularComponentcell projection membrane

PLB1 CDHR2 MYO10 GPR37L1 IFIT5 PLXND1 ABCC2 MCHR1 FSCN3 GPR88 SLC5A1 SLC19A1 CSPG4 LRP2

5.32e-0543119414GO:0031253
GeneOntologyCellularComponentseptate junction

NFASC CNTNAP1

8.57e-0521942GO:0005918
GeneOntologyCellularComponentinner dynein arm

DNAH6 DNAH2 DNAH12

9.00e-05101943GO:0036156
GeneOntologyCellularComponentbrush border membrane

PLB1 CDHR2 ABCC2 SLC5A1 SLC19A1 LRP2

1.23e-04831946GO:0031526
GeneOntologyCellularComponentactin-based cell projection

DOCK4 MYO7A CDHR2 MYO10 CDH23 NFASC NEDD4 PCDH15 FSCN3 MYO15A

2.83e-0427819410GO:0098858
GeneOntologyCellularComponentstereocilium

DOCK4 MYO7A CDH23 PCDH15 MYO15A

4.54e-04691945GO:0032420
GeneOntologyCellularComponentapical plasma membrane

PLB1 MYO7A CDHR2 SLC22A8 ABCC2 ABCG8 DSG2 SI TLR9 SLC5A1 SLC19A1 CSPG4 LRP2

6.52e-0448719413GO:0016324
GeneOntologyCellularComponentstereocilium bundle

DOCK4 MYO7A CDH23 PCDH15 MYO15A

8.45e-04791945GO:0032421
GeneOntologyCellularComponentsarcoplasmic reticulum

SRL NOS1 TMEM38B SLC2A4 OPRK1

1.37e-03881945GO:0016529
GeneOntologyCellularComponentaxonemal dynein complex

DNAH6 DNAH2 DNAH12

1.56e-03251943GO:0005858
MousePhenoabnormal cochlear hair cell inter-stereocilial links morphology

MYO7A CDH23 PCDH15 MYO15A

1.54e-0691504MP:0004577
MousePhenoabnormal motor coordination/balance

STUB1 CACNA2D2 MYO7A ADAM23 GPR37L1 CDH23 LPIN1 NFIX PCDH15 NOS1 ABCG8 DRD3 CWH43 STXBP5L PKP4 CNTNAP1 HIPK2 CACHD1 GPR88 MTMR14 LRP2 ELAVL4 SMPD1 EML1 MYO15A PCDH9

1.85e-0687315026MP:0001516
DomainCadherin_CS

CDHR2 CDH23 PCDH15 FAT4 DSG2 PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 FAT3 PCDHGA12 PCDHGA8 PCDH9

1.97e-1410919116IPR020894
DomainCADHERIN_1

CDHR2 CDH23 PCDH15 FAT4 DSG2 PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 FAT3 PCDHGA12 PCDHGA8 PCDH9

3.54e-1411319116PS00232
DomainCadherin

CDHR2 CDH23 PCDH15 FAT4 DSG2 PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 FAT3 PCDHGA12 PCDHGA8 PCDH9

3.54e-1411319116PF00028
DomainCADHERIN_2

CDHR2 CDH23 PCDH15 FAT4 DSG2 PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 FAT3 PCDHGA12 PCDHGA8 PCDH9

4.08e-1411419116PS50268
Domain-

CDHR2 CDH23 PCDH15 FAT4 DSG2 PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 FAT3 PCDHGA12 PCDHGA8 PCDH9

4.08e-14114191162.60.40.60
DomainCA

CDHR2 CDH23 PCDH15 FAT4 DSG2 PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 FAT3 PCDHGA12 PCDHGA8 PCDH9

4.70e-1411519116SM00112
DomainCadherin-like

CDHR2 CDH23 PCDH15 FAT4 DSG2 PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 FAT3 PCDHGA12 PCDHGA8 PCDH9

5.40e-1411619116IPR015919
DomainCadherin

CDHR2 CDH23 PCDH15 FAT4 DSG2 PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 FAT3 PCDHGA12 PCDHGA8 PCDH9

7.11e-1411819116IPR002126
DomainCadherin_tail

PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 PCDHGA12 PCDHGA8

9.84e-11371919PF15974
DomainCadherin_CBD

PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 PCDHGA12 PCDHGA8

9.84e-11371919IPR031904
DomainCadherin_C

PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 PCDHGA12 PCDHGA8

3.38e-10421919IPR032455
DomainCadherin_C_2

PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 PCDHGA12 PCDHGA8

3.38e-10421919PF16492
DomainCadherin_2

PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 PCDHGA12 PCDHGA8 PCDH9

1.09e-096519110PF08266
DomainCadherin_N

PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 PCDHGA12 PCDHGA8 PCDH9

1.09e-096519110IPR013164
DomainEGF

BRINP3 ADAM23 FAT4 FRAS1 FAT3 CNTNAP1 OIT3 HMCN1 SUSD1 PCSK6 TENM1 LRP2 TNR

9.38e-0723519113SM00181
DomainEGF-like_dom

ADAM23 FAT4 FRAS1 FAT3 CNTNAP1 OIT3 HMCN1 SUSD1 PRF1 PCSK6 TENM1 LRP2 TNR

1.79e-0624919113IPR000742
DomainGlycoside_hydrolase_SF

HPSE2 MGAM2 SI MANEA LCTL GUSB

1.63e-05531916IPR017853
DomainEGF_3

ADAM23 FAT4 FAT3 CNTNAP1 OIT3 HMCN1 SUSD1 PRF1 TENM1 LRP2 TNR

3.14e-0523519111PS50026
DomainEGF_1

ADAM23 FAT4 FAT3 CNTNAP1 OIT3 HMCN1 SUSD1 PRF1 TENM1 LRP2 TNR

6.58e-0525519111PS00022
DomainPlexin_cytopl

PLXND1 PLXNA1 PLXNA3

8.45e-0591913PF08337
DomainMYTH4

MYO7A MYO10 MYO15A

8.45e-0591913PS51016
DomainMyTH4

MYO7A MYO10 MYO15A

8.45e-0591913SM00139
DomainPlexin_cytoplasmic_RasGAP_dom

PLXND1 PLXNA1 PLXNA3

8.45e-0591913IPR013548
DomainPlexin

PLXND1 PLXNA1 PLXNA3

8.45e-0591913IPR031148
DomainMyTH4_dom

MYO7A MYO10 MYO15A

8.45e-0591913IPR000857
DomainMyTH4

MYO7A MYO10 MYO15A

8.45e-0591913PF00784
DomainEGF_2

ADAM23 FAT4 FAT3 CNTNAP1 OIT3 HMCN1 SUSD1 PRF1 TENM1 LRP2 TNR

9.27e-0526519111PS01186
DomainLgl_C

STXBP5L STXBP5

1.04e-0421912PF08596
DomainLgl_C_dom

STXBP5L STXBP5

1.04e-0421912IPR013905
DomainXK-related

XKR7 XKR6 XKRX

1.64e-04111913PF09815
DomainXK_rel

XKR7 XKR6 XKRX

1.64e-04111913IPR018629
DomainSemap_dom

PLXND1 PLXNA1 PLXNA3 SEMA4D

2.69e-04311914IPR001627
DomainSEMA

PLXND1 PLXNA1 PLXNA3 SEMA4D

2.69e-04311914PS51004
DomainSema

PLXND1 PLXNA1 PLXNA3 SEMA4D

2.69e-04311914SM00630
DomainSema

PLXND1 PLXNA1 PLXNA3 SEMA4D

2.69e-04311914PF01403
DomainPlexin_repeat

PLXND1 PLXNA1 PLXNA3 SEMA4D

3.05e-04321914IPR002165
DomainPSI

PLXND1 PLXNA1 PLXNA3 SEMA4D

3.05e-04321914PF01437
DomainLaminin_G

COL14A1 FAT4 FAT3 CNTNAP1 CSPG4

3.13e-04581915IPR001791
DomainDynein_heavy_chain_D4_dom

DNAH6 DNAH2 DNAH12

3.53e-04141913IPR024317
DomainDynein_heavy_dom-2

DNAH6 DNAH2 DNAH12

3.53e-04141913IPR013602
DomainDHC_N2

DNAH6 DNAH2 DNAH12

3.53e-04141913PF08393
DomainATPase_dyneun-rel_AAA

DNAH6 DNAH2 DNAH12

3.53e-04141913IPR011704
DomainAAA_8

DNAH6 DNAH2 DNAH12

3.53e-04141913PF12780
DomainAAA_5

DNAH6 DNAH2 DNAH12

3.53e-04141913PF07728
DomainEGF-like_CS

ADAM23 FAT4 FAT3 CNTNAP1 HMCN1 SUSD1 PRF1 TENM1 LRP2 TNR

3.67e-0426119110IPR013032
DomainDHC_fam

DNAH6 DNAH2 DNAH12

4.38e-04151913IPR026983
DomainDynein_heavy

DNAH6 DNAH2 DNAH12

4.38e-04151913PF03028
DomainDynein_heavy_dom

DNAH6 DNAH2 DNAH12

4.38e-04151913IPR004273
DomainEGF_Ca-bd_CS

FAT4 FAT3 OIT3 HMCN1 SUSD1 LRP2

4.83e-04971916IPR018097
DomainEGF_CA

FAT4 FAT3 OIT3 HMCN1 SUSD1 LRP2

5.39e-04991916PS01187
DomainASX_HYDROXYL

FAT4 FAT3 OIT3 HMCN1 SUSD1 LRP2

5.68e-041001916PS00010
DomainLAM_G_DOMAIN

FAT4 FAT3 CNTNAP1 CSPG4

5.96e-04381914PS50025
DomainLLGL

STXBP5L STXBP5

6.16e-0441912PF08366
DomainPPR

DENND4A DENND4C

6.16e-0441912PF01535
DomainGal_mutarotase_N

MGAM2 SI

6.16e-0441912IPR031727
DomainLethal2_giant

STXBP5L STXBP5

6.16e-0441912IPR000664
DomainNtCtMGAM_N

MGAM2 SI

6.16e-0441912PF16863
DomainLLGL2

STXBP5L STXBP5

6.16e-0441912IPR013577
DomainLaminin_G_2

FAT4 FAT3 CNTNAP1 CSPG4

7.26e-04401914PF02210
DomainEGF-type_Asp/Asn_hydroxyl_site

FAT4 FAT3 OIT3 HMCN1 SUSD1 LRP2

7.73e-041061916IPR000152
DomainVWA_N

CACNA2D2 CACHD1

1.02e-0351912IPR013608
DomainVWA_N

CACNA2D2 CACHD1

1.02e-0351912PF08399
DomainPSI

PLXND1 PLXNA1 PLXNA3 SEMA4D

1.05e-03441914IPR016201
DomainLamG

FAT4 FAT3 CNTNAP1 CSPG4

1.05e-03441914SM00282
DomainGrowth_fac_rcpt_

BRINP3 FAT4 FRAS1 HMCN1 SUSD1 PCSK6 LRP2

1.13e-031561917IPR009030
DomainPSI

PLXND1 PLXNA1 PLXNA3 SEMA4D

1.24e-03461914SM00423
DomainLNS2

LPIN1 PITPNM1

1.52e-0361912IPR013209
DomainLNS2

LPIN1 PITPNM1

1.52e-0361912SM00775
DomainGlyco_hydro_31_AS

MGAM2 SI

1.52e-0361912IPR030458
DomainHELP

EML3 EML1

1.52e-0361912PF03451
DomainHaem_d1

STXBP5L STXBP5

1.52e-0361912IPR011048
DomainLNS2

LPIN1 PITPNM1

1.52e-0361912PF08235
DomainLNS2/PITP

LPIN1 PITPNM1

1.52e-0361912IPR031315
DomainHELP

EML3 EML1

1.52e-0361912IPR005108
DomainEGF_CA

FAT4 FAT3 OIT3 HMCN1 SUSD1 LRP2

1.60e-031221916SM00179
DomainPentatricopeptide_repeat

DENND4A IFIT5 DENND4C

1.60e-03231913IPR002885
DomainEGF-like_Ca-bd_dom

FAT4 FAT3 OIT3 HMCN1 SUSD1 LRP2

1.74e-031241916IPR001881
DomainEGF_CA

FAT4 FAT3 HMCN1 SUSD1 LRP2

1.89e-03861915PF07645
DomainGlyco_hydro_31

MGAM2 SI

2.11e-0371912IPR000322
DomainGlyco_hydro_31

MGAM2 SI

2.11e-0371912PF01055
DomainGLYCOSYL_HYDROL_F31_1

MGAM2 SI

2.11e-0371912PS00129
DomainIPT

PLXND1 PLXNA1 PLXNA3

2.57e-03271913SM00429
DomainPPR

DENND4A DENND4C

2.80e-0381912PS51375
DomainTrefoil

MGAM2 SI

2.80e-0381912PF00088
DomainEGF_extracell

ADAM23 TENM1 LRP2 TNR

3.31e-03601914IPR013111
DomainEGF_2

ADAM23 TENM1 LRP2 TNR

3.31e-03601914PF07974
DomainP_TREFOIL_2

MGAM2 SI

3.57e-0391912PS51448
DomainPD

MGAM2 SI

3.57e-0391912SM00018
DomainAAA

ATAD5 ABCC2 DNAH6 DNAH2 DNAH12 MCM9

3.68e-031441916SM00382
DomainAAA+_ATPase

ATAD5 ABCC2 DNAH6 DNAH2 DNAH12 MCM9

3.68e-031441916IPR003593
DomainTIG

PLXND1 PLXNA1 PLXNA3

3.83e-03311913PF01833
DomainArm

ANKAR PKP4 SPAG6

3.83e-03311913PF00514
Pubmed

Maturation of postnatally generated olfactory bulb granule cells depends on functional γ-protocadherin expression.

PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA12

9.68e-1315195723515096
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 PCDHGA12 PCDHGA8 PCDH9

1.28e-11741951010817752
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 PCDHGA12 PCDHGA8 PCDH9

1.93e-11771951010835267
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 PCDHGA12 PCDHGA8 PCDH9

2.85e-11801951010716726
Pubmed

Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.

PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA12

1.68e-1028195715347688
Pubmed

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.

PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 PCDHGA12 PCDHGA8

1.69e-1068195911230163
Pubmed

A striking organization of a large family of human neural cadherin-like cell adhesion genes.

PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 PCDHGA12 PCDHGA8

2.85e-1072195910380929
Pubmed

Functional significance of isoform diversification in the protocadherin gamma gene cluster.

PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA12

7.40e-1034195722884324
Pubmed

A differential developmental pattern of spinal interneuron apoptosis during synaptogenesis: insights from genetic analyses of the protocadherin-gamma gene cluster.

PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA12

5.03e-0944195719029045
Pubmed

Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.

PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA12

3.26e-0857195732633719
Pubmed

Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia.

MYO7A CDH23 PCDH15 MYO15A

3.31e-087195421436032
Pubmed

Tonotopic gradient in the developmental acquisition of sensory transduction in outer hair cells of the mouse cochlea.

MYO7A CDH23 PCDH15 MYO15A

1.18e-079195419339464
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

DENND4A IFIT5 PTBP1 TTC3 PXDN CLCN4 ABCC2 DNAH6 BAHCC1 PLXNA3 RGPD2 PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 DNAH2 CCNH PHF20L1 SUSD1 PCDHGA12 CSPG4 TENM1 PCDHGA8

1.64e-0714421952635575683
Pubmed

Survey of the frequency of USH1 gene mutations in a cohort of Usher patients shows the importance of cadherin 23 and protocadherin 15 genes and establishes a detection rate of above 90%.

MYO7A CDH23 PCDH15

1.74e-073195316679490
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

DENND4A PLEKHM2 SCFD1 PLXNA1 GPD2 DSG2 STXBP5 PIGS FNDC3A MON1A TMEM38B DENND4C FAM171A1 TENM1 LRP2

1.93e-075041951534432599
Pubmed

Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.

PLXND1 PLXNA1 PLXNA3 SEMA4D

6.59e-0713195410520995
Pubmed

Physical and functional interaction between protocadherin 15 and myosin VIIa in mechanosensory hair cells.

MYO7A CDH23 PCDH15

6.91e-074195316481439
Pubmed

Control of stereocilia length during development of hair bundles.

CDH23 PCDH15 MYO15A

6.91e-074195337011103
Pubmed

Mechanotransduction is required for establishing and maintaining mature inner hair cells and regulating efferent innervation.

MYO7A PCDH15 MYO15A

6.91e-074195330275467
Pubmed

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction.

IRAK1 TLR7 TLR9

6.91e-074195315767370
Pubmed

Interactions in the network of Usher syndrome type 1 proteins.

MYO7A CDH23 PCDH15

1.72e-065195315590703
Pubmed

Cochlear outer hair cells undergo an apical circumference remodeling constrained by the hair bundle shape.

MYO7A CDH23 MYO15A

1.72e-065195320332152
Pubmed

Characterization of Usher syndrome type I gene mutations in an Usher syndrome patient population.

MYO7A CDH23 PCDH15

1.72e-065195315660226
Pubmed

Usher I syndrome: unravelling the mechanisms that underlie the cohesion of the growing hair bundle in inner ear sensory cells.

MYO7A CDH23 PCDH15

1.72e-065195316219682
Pubmed

Digenic inheritance of deafness caused by 8J allele of myosin-VIIA and mutations in other Usher I genes.

MYO7A CDH23 PCDH15

1.72e-065195322381527
Pubmed

The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity.

TLR7 SMPDL3A TLR9

3.43e-066195326095358
Pubmed

Impact of the Usher syndrome on olfaction.

MYO7A CDH23 PCDH15

3.43e-066195326620972
Pubmed

TLR2 signaling depletes IRAK1 and inhibits induction of type I IFN by TLR7/9.

IRAK1 TLR7 TLR9

3.43e-066195322227568
Pubmed

Cochlear developmental defect and background-dependent hearing thresholds in the Jackson circler (jc) mutant mouse.

CDH23 PCDH15 MYO15A

5.98e-067195316962269
Pubmed

Differential expression of individual gamma-protocadherins during mouse brain development.

PCDHGA4 PCDHGA3 PCDHGA12

5.98e-067195315964765
Pubmed

Tails of unconventional myosins.

MYO7A MYO10 MYO15A

5.98e-067195311212352
Pubmed

Role of myosin VIIa and Rab27a in the motility and localization of RPE melanosomes.

MYO7A CDH23 PCDH15

5.98e-067195315572405
Pubmed

Usher Syndrome Type I

MYO7A CDH23 PCDH15

5.98e-067195320301442
Pubmed

[Studies on the genetics and pathology of the development of 8 labyrinth mutants (deaf-waltzer-shaker mutants) in the mouse (Mus musculus)].

MYO7A CDH23 MYO15A

5.98e-067195313853422
Pubmed

Zic2-dependent axon midline avoidance controls the formation of major ipsilateral tracts in the CNS.

LHX9 PLXNA1 ZIC2 ELAVL4

7.81e-0623195424360543
Pubmed

Microarray-based mutation analysis of 183 Spanish families with Usher syndrome.

MYO7A CDH23 PCDH15

9.52e-068195319683999
Pubmed

Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane.

MYO7A CDH23 PCDH15

9.52e-068195321165971
Pubmed

UMD-USHbases: a comprehensive set of databases to record and analyse pathogenic mutations and unclassified variants in seven Usher syndrome causing genes.

MYO7A CDH23 PCDH15

9.52e-068195318484607
Pubmed

Molecular basis of human Usher syndrome: deciphering the meshes of the Usher protein network provides insights into the pathomechanisms of the Usher disease.

MYO7A CDH23 PCDH15

9.52e-068195316545802
Pubmed

Critical role of IkappaB Kinase alpha in TLR7/9-induced type I IFN production by conventional dendritic cells.

IRAK1 TLR7 TLR9

1.42e-059195320200270
Pubmed

Antiviral protein Viperin promotes Toll-like receptor 7- and Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells.

IRAK1 TLR7 TLR9

1.42e-059195321435586
Pubmed

A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth.

MYO7A CDH23 PCDH15

1.42e-059195318339676
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

PLXND1 PXDN CDIPT PRSS21 HECTD1 PLXNA1 PLXNA3 FAT4 FRAS1 DSG2 PIGS CNTNAP1 SLC35A1 MANEA CACHD1 TMEM38B GUSB CSPG4 RNFT1 SMPD1

1.54e-0512011952035696571
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MYO7A MYO10 IRAK1 PLXND1 TTC3 FOCAD URB1 PLEKHM2 PPP2R3C HECTD1 PLXNA1 BAHCC1 PLXNA3 FRAS1 AOC2 EML3 CLDN23 MTMR14 CSPG4

1.64e-0511051951935748872
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

RHOJ HIPK1 PLXND1 NEDD4 PRSS21 HCFC2 PLXNA1 PLXNA3 SEMA4D TENT4B PRSS41 DNAH2 HIPK2 LRP2 KCNH5

1.77e-057301951534857952
Pubmed

Massively parallel DNA sequencing facilitates diagnosis of patients with Usher syndrome type 1.

MYO7A CDH23 PCDH15

2.02e-0510195324618850
Pubmed

Usher protein functions in hair cells and photoreceptors.

MYO7A CDH23 PCDH15

2.02e-0510195324239741
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DOCK4 MYO10 HIPK1 NEDD4 FOCAD PXDN PLEKHM2 FRAS1 STXBP5 R3HDM2 STRIP1

2.10e-054071951112693553
Pubmed

Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.

MYO7A CDH23 PCDH15

2.77e-0511195331776257
Pubmed

Expression of toll-like receptors in HPV-positive and HPV-negative oropharyngeal squamous cell carcinoma--an in vivo and in vitro study.

TLR7 TLR9

3.13e-052195225941114
Pubmed

Evidence of genetic heterogeneity in Alberta Hutterites with Usher syndrome type I.

MYO7A PCDH15

3.13e-052195222690115
Pubmed

Acid sphingomyelinase is a key regulator of cytotoxic granule secretion by primary T lymphocytes.

PRF1 SMPD1

3.13e-052195219525969
Pubmed

Rethinking isolated cleft lip and palate as a syndrome.

IGSF9 HMCN1

3.13e-052195229500156
Pubmed

Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo.

TLR7 TLR9

3.13e-052195224342772
Pubmed

Investigation of MYO15A and MYO7A Mutations in Iranian Patients with Nonsyndromic Hearing Loss.

MYO7A MYO15A

3.13e-052195231997689
Pubmed

The Role of TLR7 and TLR9 in the Pathogenesis of Systemic Sclerosis.

TLR7 TLR9

3.13e-052195238892317
Pubmed

Polymorphisms in Toll-Like Receptors (TLRs)-7 and 9 Genes in Indian Population with Progressive and Nonprogressive HIV-1 Infection.

TLR7 TLR9

3.13e-052195230793925
Pubmed

Blocking toll-like receptors 7 and 9 reduces postinterventional remodeling via reduced macrophage activation, foam cell formation, and migration.

TLR7 TLR9

3.13e-052195222628437
Pubmed

Nucleic Acid-Targeting Pathways Promote Inflammation in Obesity-Related Insulin Resistance.

TLR7 TLR9

3.13e-052195227373163
Pubmed

Elmo2 Is a Regulator of Insulin-dependent Glut4 Membrane Translocation.

SLC2A4 ELMO2

3.13e-052195227226625
Pubmed

Human plasmacytoid dendritic cells mount a distinct antiviral response to virus-infected cells.

TLR7 TLR9

3.13e-052195233811059
Pubmed

Effects of Single-Nucleotide Polymorphisms in the TLR7 and TLR9 Genes of Asthmatic Children.

TLR7 TLR9

3.13e-052195230373864
Pubmed

Structure of a force-conveying cadherin bond essential for inner-ear mechanotransduction.

CDH23 PCDH15

3.13e-052195223135401
Pubmed

Using thermal scanning assays to test protein-protein interactions of inner-ear cadherins.

CDH23 PCDH15

3.13e-052195229261728
Pubmed

Single nucleotide polymorphisms of toll-like receptor 7 and toll-like receptor 9 in hepatitis C virus infection patients from central China.

TLR7 TLR9

3.13e-052195224532514
Pubmed

Sex bias in susceptibility to MCMV infection: implication of TLR9.

TLR7 TLR9

3.13e-052195223028824
Pubmed

The Role of the Oxidative State and Innate Immunity Mediated by TLR7 and TLR9 in Lupus Nephritis.

TLR7 TLR9

3.13e-052195237894915
Pubmed

The CD2 isoform of protocadherin-15 is an essential component of the tip-link complex in mature auditory hair cells.

PCDH15 MYO15A

3.13e-052195224940003
Pubmed

Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice.

TLR7 TLR9

3.13e-052195219944565
Pubmed

Emerging roles of TLR7 and TLR9 in murine SLE.

TLR7 TLR9

3.13e-052195219846276
Pubmed

Increased expression of Toll-like receptors 7 and 9 in myasthenia gravis thymus characterized by active Epstein-Barr virus infection.

TLR7 TLR9

3.13e-052195226723518
Pubmed

Differences in codon bias and GC content contribute to the balanced expression of TLR7 and TLR9.

TLR7 TLR9

3.13e-052195226903634
Pubmed

Progressive hearing loss and increased susceptibility to noise-induced hearing loss in mice carrying a Cdh23 but not a Myo7a mutation.

MYO7A CDH23

3.13e-052195214648237
Pubmed

Effect of toll-like receptor 7 and 9 targeted therapy to prevent the development of hepatocellular carcinoma.

TLR7 TLR9

3.13e-052195224990399
Pubmed

A mouse model for nonsyndromic deafness (DFNB12) links hearing loss to defects in tip links of mechanosensory hair cells.

CDH23 PCDH15

3.13e-052195219270079
Pubmed

Association of single-nucleotide polymorphisms in TLR7 (Gln11Leu) and TLR9 (1635A/G) with a higher CD4T cell count during HIV infection.

TLR7 TLR9

3.13e-052195224747071
Pubmed

Toll-like receptor (TLR) 7 decreases and TLR9 increases the airway responses in mice with established allergic inflammation.

TLR7 TLR9

3.13e-052195224041926
Pubmed

[Usher type I syndrome in children: genotype/phenotype correlation and cochlear implant benefits].

MYO7A CDH23

3.13e-052195218323324
Pubmed

Cdh23 mutations in the mouse are associated with retinal dysfunction but not retinal degeneration.

MYO7A CDH23

3.13e-052195214609561
Pubmed

Allelic hierarchy of CDH23 mutations causing non-syndromic deafness DFNB12 or Usher syndrome USH1D in compound heterozygotes.

CDH23 PCDH15

3.13e-052195221940737
Pubmed

Digenic inheritance of deafness caused by mutations in genes encoding cadherin 23 and protocadherin 15 in mice and humans.

CDH23 PCDH15

3.13e-052195215537665
Pubmed

Opposing impact of B cell-intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation.

TLR7 TLR9

3.13e-052195224711620
Pubmed

Human Plasmacytoid Dendritic Cells and Cutaneous Melanoma.

TLR7 TLR9

3.13e-052195232054102
Pubmed

Necrotizing lymphadenitis may be induced by overexpression of Toll-like receptor7 (TLR7) caused by reduced TLR9 transport in plasmacytoid dendritic cells (PDCs).

TLR7 TLR9

3.13e-052195233994431
Pubmed

Overexpression of TLR7 and TLR9 Occurs Before Onset Symptoms In First-Degree Relatives of Rheumatoid Arthritis Patients.

TLR7 TLR9

3.13e-052195234272096
Pubmed

Cofactors required for TLR7- and TLR9-dependent innate immune responses.

TLR7 TLR9

3.13e-052195222423970
Pubmed

Cryptic genomic abnormalities associated with coexpression of KOR-SA3544 and NG.2 in proB acute lymphoblastic leukemia.

OPRK1 CSPG4

3.13e-052195218767415
Pubmed

Hyper-responsive Toll-like receptor 7 and 9 activation in NADPH oxidase-deficient B lymphoblasts.

TLR7 TLR9

3.13e-052195226340429
Pubmed

Increased expression of TLR7 and TLR9 in alopecia areata.

TLR7 TLR9

3.13e-052195231571275
Pubmed

Up-regulation of Toll-like receptors 7 and 9 and its potential implications in the pathogenic mechanisms of LMNA-related myopathies.

TLR7 TLR9

3.13e-052195229895224
Pubmed

Impact of TLR7 and TLR9 polymorphisms on susceptibility to placental infections and pregnancy complications.

TLR7 TLR9

3.13e-052195234102513
Pubmed

A role of lipin in human obesity and insulin resistance: relation to adipocyte glucose transport and GLUT4 expression.

LPIN1 SLC2A4

3.13e-052195217035674
Pubmed

A novel missense mutation locus of cadherin 23 and the interaction of cadherin 23 and protocadherin 15 in a patient with usher syndrome.

CDH23 PCDH15

3.13e-052195232835555
Pubmed

Impact of TLR9 and TLR7 gene polymorphisms on prognosis and survival of patients with oral squamous cell carcinoma.

TLR7 TLR9

3.13e-052195238850110
Pubmed

Mutation analysis of the MYO7A and CDH23 genes in Japanese patients with Usher syndrome type 1.

MYO7A CDH23

3.13e-052195220844544
Pubmed

Identification and characterization of human LLGL4 gene and mouse Llgl4 gene in silico.

STXBP5L STXBP5

3.13e-052195214767561
Pubmed

Oligodendrocyte Neurofascin Independently Regulates Both Myelin Targeting and Sheath Growth in the CNS.

NFASC CNTNAP1

3.13e-052195231761670
Pubmed

TLR9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus.

TLR7 TLR9

3.13e-052195225751136
Pubmed

Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections.

TLR7 TLR9

3.13e-052195218806803
Pubmed

Double homozygous waltzer and Ames waltzer mice provide no evidence of retinal degeneration.

CDH23 PCDH15

3.13e-052195219057657
InteractionFBXO2 interactions

STUB1 CACNA2D2 CDHR2 ADAM23 PLXND1 GDF9 ERVMER34-1 PXDN IGSF9 COL14A1 PLXNA1 PLXNA3 SEMA4D FRAS1 PIGS CNTNAP1 CACHD1 SUSD1 GUSB CSPG4 LRP2 PCDH9

6.70e-1141119222int:FBXO2
InteractionPCDHGA12 interactions

PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA4 PCDHGA12

1.81e-08101925int:PCDHGA12
InteractionPCDHGA4 interactions

PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA12 PCDHGA8

2.76e-08341927int:PCDHGA4
InteractionSDF2L1 interactions

CACNA2D2 IRAK1 ERVMER34-1 PXDN PLXNA1 PLXNA3 SEMA4D FRAS1 CNTNAP1 SLC2A4 LMBR1L GUSB PRF1 PCSK6 CSPG4

4.96e-0732219215int:SDF2L1
InteractionPCDHGA9 interactions

PCDHGB1 PCDHGA9 PCDHGA4 PCDHGA3 PCDHGA12 PCDHGA8

6.18e-07331926int:PCDHGA9
InteractionPCDHGB1 interactions

GPD2 FAT4 PCDHGB1 PCDHGA9 PCDHGA7 FAM171A1 PCDHGA12 PCDH9

7.04e-07771928int:PCDHGB1
InteractionLGALS1 interactions

STUB1 CDHR2 PLXND1 HRAS PLXNA1 SEMA4D FAT4 FRAS1 FAT3 MUC16 FAM171A1 LCTL CSPG4 LRP2 PCDH9

7.30e-0733219215int:LGALS1
InteractionRYK interactions

CNNM2 FAT4 DSG2 PCDHGA7 PCDHGA6 FAT3 PKP4 FAM171A1 PCDHGA12 SLC19A1 CSPG4 PCDH9

9.45e-0721219212int:RYK
InteractionPTPRK interactions

RHOJ CACNA2D2 PXDN PLXNA1 PLXNA3 FRAS1 PCDHGB1 PKP4 OIT3 SUSD1 LMBR1L

1.09e-0617719211int:PTPRK
InteractionSIRPD interactions

CACNA2D2 PLXNA1 PLXNA3 FRAS1 GUSB PRF1 PCSK6 CSPG4

1.65e-06861928int:SIRPD
InteractionPCDHGA7 interactions

PCDHGB1 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA12

3.39e-06251925int:PCDHGA7
InteractionC1orf54 interactions

BRINP3 PLXND1 PXDN PLXNA1 PLXNA3 SEMA4D CNTNAP1 CACHD1 GUSB PRF1

4.72e-0616719210int:C1orf54
InteractionPCDHGA8 interactions

PCDHGA9 PCDHGA4 PCDHGA8

8.39e-0651923int:PCDHGA8
InteractionC1QTNF9B interactions

IRAK1 COL14A1 PLXNA1 GUSB PCSK6 CSPG4

8.72e-06511926int:C1QTNF9B
InteractionSFTPC interactions

CNNM2 CACNA2D2 PLXND1 ERVMER34-1 NEDD4 GJA8 PLXNA1 PLXNA3 CNTNAP1 SUSD1 PRF1

9.68e-0622219211int:SFTPC
InteractionRNASE13 interactions

CACNA2D2 COL14A1 SUSD1 LRP2

1.33e-05161924int:RNASE13
InteractionTRGV3 interactions

CACNA2D2 FRAS1 CACHD1 GUSB PCSK6 CSPG4

1.36e-05551926int:TRGV3
InteractionBTNL2 interactions

CACNA2D2 IGSF9 PLXNA1 PLXNA3 SEMA4D CNTNAP1 GUSB PRF1 CSPG4

1.82e-051551929int:BTNL2
InteractionINSL5 interactions

CACNA2D2 PXDN COL14A1 CNTNAP1 SUSD1 SMPD1

1.85e-05581926int:INSL5
InteractionNCR3 interactions

CACNA2D2 PLXNA1 FRAS1 CNTNAP1 GUSB PRF1 PCSK6 CSPG4

1.98e-051201928int:NCR3
InteractionCBLN4 interactions

CACNA2D2 IGSF9 PLXNA1 PLXNA3 FRAS1 GUSB PCSK6 CSPG4

2.99e-051271928int:CBLN4
InteractionPCDHGA5 interactions

PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 FNDC3A PCDHGA8

2.99e-05631926int:PCDHGA5
InteractionPCDHGA3 interactions

PCDHGA9 PCDHGA4 PCDHGA3

6.86e-0591923int:PCDHGA3
InteractionPCDHGA6 interactions

GDF9 PCDHGA7 PCDHGA6 PCDHGA4

7.31e-05241924int:PCDHGA6
InteractionSLURP1 interactions

CACNA2D2 ERVMER34-1 PXDN PLXNA1 PLXNA3 CNTNAP1 GUSB PRF1

7.31e-051441928int:SLURP1
InteractionST8SIA4 interactions

PLXNA1 PLXNA3 SEMA4D FRAS1 CACHD1 SUSD1

1.52e-04841926int:ST8SIA4
Cytoband5q31

PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 PCDHGA12 PCDHGA8

1.87e-0911519695q31
CytobandEnsembl 112 genes in cytogenetic band chr5q31

GDF9 PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 PCDHGA12 PCDHGA8

7.21e-0729819610chr5q31
GeneFamilyClustered protocadherins

PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 PCDHGA12 PCDHGA8

1.00e-0964134920
GeneFamilyCadherin related

CDHR2 CDH23 PCDH15 FAT4 FAT3

1.20e-0717134524
GeneFamilyPlexins

PLXND1 PLXNA1 PLXNA3

3.24e-0591343683
GeneFamilyBlood group antigens|XK related family

XKR7 XKR6 XKRX

6.29e-05111343955
GeneFamilyDyneins, axonemal

DNAH6 DNAH2 DNAH12

2.51e-04171343536
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

ANKAR PKP4 ARMC9 SPAG6

2.85e-04431344409
GeneFamilyCD molecules|Toll like receptors

TLR7 TLR9

2.36e-03101342948
CoexpressionGSE3920_UNTREATED_VS_IFNA_TREATED_ENDOTHELIAL_CELL_UP

DOCK4 TLR7 PLXNA1 GPD2 SEMA4D FNDC3A LRRC58 TGFB3 GUSB PRF1

8.14e-0717519510M6684
CoexpressionGSE8685_IL2_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_DN

TTC3 UBE2V2 CCDC15 IGSF9 LMNTD1 ST8SIA1 TGFB3 PHF20L1

1.29e-051441958M335
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH15 FAT4 FRAS1 STXBP5L KIF26B FAT3 HMCN1 TENM1 LRP2 ELAVL4 MYO15A

6.01e-10184195112cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH15 FAT4 FRAS1 STXBP5L KIF26B FAT3 HMCN1 TENM1 LRP2 ELAVL4 MYO15A

6.01e-10184195112b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH15 FAT4 FRAS1 STXBP5L KIF26B FAT3 HMCN1 TENM1 LRP2 ELAVL4 MYO15A

6.01e-1018419511ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK4 MYO10 HPSE2 PGR TMEM132C SMPDL3A PCDH15 COL14A1 FRAS1 FAT3 HMCN1

7.99e-1018919511203c80030df08ae112f9ae4043709f455d87ce89
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Hsd11b1_Endou|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BRINP3 PLB1 PLXND1 PCDH15 IGSF9 FRAS1 FAT3 GPR88 KCNH5

3.45e-081581959c8af8964a140acb2987e3b4906d72c546108d229
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDHR2 HPSE2 ANKAR PCDH15 ABCC2 HEPHL1 FRAS1 FAT3 TENM1

4.28e-081621959bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

SYNDIG1 PGR TMEM132C COL14A1 MCHR1 KIF26B PCDHGA7 PCDHGA2 TGFB3

9.16e-081771959cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

SYNDIG1 PGR TMEM132C COL14A1 MCHR1 KIF26B PCDHGA7 PCDHGA2 TGFB3

9.16e-081771959db222faaecbe5600da39277243c4e7e764eb63c9
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK4 RHOJ MYO10 CDH23 NFASC TMEM132C PCDH15 FAT3 HMCN1

1.91e-071931959b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TEX26 DNAH6 LMNTD1 DRC7 CWH43 DNAH2 MUC16 SPAG6 DNAH12

2.48e-071991959542ec45c931b40738df1f3777b00c83be33a514a
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TEX26 DNAH6 LMNTD1 DRC7 CWH43 DNAH2 MUC16 SPAG6 DNAH12

2.48e-0719919592498237b9e895ca4826a3378d9d40989968df72b
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HPSE2 ANKAR PCDH15 ABCC2 HEPHL1 FRAS1 TENM1 MYO15A

2.59e-07145195896712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-4|TCGA-Breast / Sample_Type by Project: Shred V9

MYO10 IRAK1 LPIN1 CLCN4 MGAM2 OPRK1 FAM171A1 CDK2AP1

1.23e-06178195844b5ba4e8788d3973749a1717e427647ac4c8579
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO10 GPR37L1 TMEM132C PCDH15 OLIG1 IFI44 CSPG4 TNR

1.45e-0618219588a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO10 GPR37L1 TMEM132C PCDH15 OLIG1 IFI44 CSPG4 TNR

1.45e-061821958e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

BRINP3 RHOJ HPSE2 TMEM132C FAT4 HIPK2 ST8SIA1 TGFB3

1.70e-0618619587def03dd856b765bd3f493288641981c4f7fd26e
ToppCellNon-neuronal-Non-dividing-OPC-OPC|World / Primary Cells by Cluster

BRINP3 MYO10 PCDH15 OLIG1 HIPK2 CSPG4 TNR PCDH9

1.92e-061891958ddf5be73912570c32c50f4ac2902da9b590526f8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 COL14A1 DNAH6 NOS1 PKP4 XKR6 DENND4C PCDH9

1.92e-061891958e059be2965cca70ff5576df055d0af1775b76e00
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 ADAM23 PFKFB3 FRAS1 CWH43 KIF26B FAM171A1 SUSD1

1.92e-061891958c9565e962a13a7713056ec3dbb1b67d24f9889c7
ToppCellNon-neuronal-Non-dividing-OPC|World / Primary Cells by Cluster

BRINP3 MYO10 PCDH15 OLIG1 HIPK2 CSPG4 TNR PCDH9

1.92e-06189195813848a031ab896b4b24c8319e4745b9b17ff9cfd
ToppCellNon-neuronal-Non-dividing-OPC-OPC-30|World / Primary Cells by Cluster

BRINP3 MYO10 PCDH15 OLIG1 HIPK2 CSPG4 TNR PCDH9

1.92e-061891958313d165fad541ec6e8dd524b88856e2c93eeb681
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHOJ MYO7A ADAM23 MYO10 PLXND1 PXDN FAM171A1 OIT3

2.08e-0619119581924af7d8b0a0b892e480a9fd6d874941b0c0b5d
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHOJ MYO7A ADAM23 MYO10 PLXND1 PXDN FAM171A1 OIT3

2.08e-06191195888f91e57a1409bdeb91e9bf47510a6fb998a1bf5
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

DOCK4 RHOJ MYO10 HPSE2 FRAS1 KIF26B FAT3 HMCN1

2.16e-06192195862904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DOCK4 HPSE2 PGR SMPDL3A PCDH15 COL14A1 ST8SIA1 HMCN1

2.24e-0619319589f69edc97b868d23998abc98928a2e89a885ef8a
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

RHOJ TMEM132C COL14A1 FAT4 FRAS1 CNTNAP1 HMCN1 LRRD1

2.24e-0619319586ef9007c9d18fb775d08fb20cdf954a28d54d7eb
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

RHOJ ADAM23 SYNDIG1 COL14A1 CNTNAP1 TGFB3 HMCN1 PCDHGA12

2.24e-061931958194e7fa00a50cc4e026987b715323d125d79594e
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

RHOJ TMEM132C COL14A1 FAT4 FRAS1 CNTNAP1 HMCN1 LRRD1

2.24e-061931958e4ea7ce011a80b81b841c907719aa532bed39d2e
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

RHOJ TMEM132C COL14A1 FAT4 FRAS1 CNTNAP1 HMCN1 LRRD1

2.24e-061931958cf2461af78f65616ce40d552ee9452295e3895ed
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK4 RHOJ MYO10 TMEM132C PCDH15 FAT3 ST8SIA1 HMCN1

2.24e-06193195899525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK4 MYO10 HPSE2 TMEM132C PCDH15 FAT4 FAT3 HMCN1

2.33e-061941958011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFASC CLCN4 OLIG1 SEMA4D MCHR1 GPR88 OPRK1 PCDH9

2.33e-061941958ba529c051f248d29f4222f4bc9801ba233859093
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

BRINP3 HPSE2 PGR SMPDL3A PCDH15 COL14A1 ST8SIA1 HMCN1

2.33e-06194195871d3c7448b1734de54187f902f65649f9283bd4c
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHOJ MYO7A ADAM23 PLXND1 PXDN FAM171A1 OIT3 HMCN1

2.42e-06195195812ba6d95e42d06b1991b011043c0e3370a7b4131
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

COL14A1 NOS1 FAT3 MUC16 LCN2 OPRK1 HMCN1 MYO15A

2.42e-06195195819853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

COL14A1 NOS1 FAT3 MUC16 LCN2 OPRK1 HMCN1 MYO15A

2.42e-061951958d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC HPSE2 PGR PXDN COL14A1 FAT4 KIF26B ST8SIA1

2.52e-061961958a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC HPSE2 PGR PXDN COL14A1 FAT4 KIF26B ST8SIA1

2.52e-0619619583e6803587d8566fd08cb8b290be3b6461743d79c
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

HPSE2 XKR7 PCDH15 STXBP5L LRP2 ELAVL4 TNR

2.72e-061391957a1945b07f177cde40e7eea03a19236ce76165857
ToppCellFetal_29-31_weeks|World / Lineage, Cell type, age group and donor

HPSE2 PXDN COL14A1 FAT4 FRAS1 KIF26B FAT3 FAM171A1

2.82e-0619919585b9d355795dd03a22f0961dfd143425c367a4654
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPR37L1 TMEM132C PCDH15 OLIG1 NOS1 STXBP5L CSPG4 TNR

2.82e-06199195819a97e27a4758e794ce7246d295e112b47931a48
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPR37L1 TMEM132C PCDH15 OLIG1 NOS1 STXBP5L CSPG4 TNR

2.82e-061991958e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPR37L1 TMEM132C PCDH15 OLIG1 NOS1 STXBP5L CSPG4 TNR

2.82e-061991958333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

NFASC PCDH15 FAT4 FRAS1 FAT3 ST8SIA1 TGFB3 HMCN1

2.92e-062001958aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

NFASC PCDH15 FAT4 FRAS1 FAT3 ST8SIA1 TGFB3 HMCN1

2.92e-062001958a510deaada669e690329183e18df02870bd204b3
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFASC NEDD4 OLIG1 SEMA4D LRRC58 PCSK6 EML1 PCDH9

2.92e-062001958f0c338877e39226a90c4effe12f6501d33542a73
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

BRINP3 PXDN PCDH15 STXBP5L KIF26B CSPG4 TENM1 TNR

2.92e-062001958961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

BRINP3 PXDN PCDH15 STXBP5L KIF26B CSPG4 TENM1 TNR

2.92e-062001958f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

BRINP3 PXDN PCDH15 STXBP5L KIF26B CSPG4 TENM1 TNR

2.92e-062001958cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK4 RHOJ MYO10 NFASC PCDH15 FRAS1 FAT3 HMCN1

2.92e-062001958e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

BRINP3 PXDN PCDH15 STXBP5L KIF26B CSPG4 TENM1 TNR

2.92e-062001958c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

BRINP3 PXDN PCDH15 STXBP5L KIF26B CSPG4 TENM1 TNR

2.92e-0620019584fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

BRINP3 PXDN PCDH15 STXBP5L KIF26B CSPG4 TENM1 TNR

2.92e-062001958310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NFASC PCDH15 FAT4 FRAS1 FAT3 ST8SIA1 TGFB3 HMCN1

2.92e-062001958dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

HPSE2 XKR7 PCDH15 STXBP5L DNAH2 ELAVL4 TNR

3.76e-061461957c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCelldroplet-Heart-nan-24m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO10 CCDC15 ARHGAP25 FAT4 CNTNAP1 SUSD1 MCM9

9.09e-061671957a35ace2c722936d2a3e1f0826e5b6ec6b1340d2b
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D2 PGR MCHR1 XKR6 GPR88 OPRK1 PTPN5

9.46e-061681957b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D2 PGR MCHR1 XKR6 GPR88 OPRK1 PTPN5

9.46e-061681957b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CACUL1 HPSE2 CCDC15 ARHGAP25 DNAH6 FAT4 HMCN1

1.10e-051721957bfb87a281a9cf6ad45b310bf8104fc0ab382b549
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CACUL1 HPSE2 CCDC15 ARHGAP25 DNAH6 FAT4 HMCN1

1.10e-051721957c6bc78fd63c9479a84ec0552b55c89750cad0fa5
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_GPR21|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HPSE2 GPR63 GPD2 FRAS1 CACHD1 OPRK1 CSPG4

1.19e-0517419570df738309b7b6e77675ea74e7a87e66601b0073d
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCDH15 COL14A1 AOC2 MUC16 TGFB3 LRP2 ELAVL4

1.19e-0517419574da79da7a09ee1e345102c5331675ebcdbe56171
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MYO7A NEDD4 ANKAR RBM14 PLXNA1 ST8SIA1 XKR6

1.28e-051761957437cfc5e06416bb0fc76d1f9dc106f74e279e880
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HPSE2 GPR63 TEX26 GPD2 FRAS1 CACHD1 OPRK1

1.33e-05177195764fbf799e7b0c4003b2f486cc41b0f7e7c11ea0c
ToppCellfacs-Marrow-B-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRINP3 GPR37L1 NFASC OLIG1 CSPG4 EML1 PCDH9

1.48e-051801957c54af6fb11484dacd3efa1f10a487376ff820a5e
ToppCellfacs-Marrow-B-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRINP3 GPR37L1 NFASC OLIG1 CSPG4 EML1 PCDH9

1.48e-05180195707ac979b21be2425294d9818c48b5a1e6f014c19
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO10 TMEM132C PCDH15 FRAS1 FAT3 ST8SIA1 HMCN1

1.53e-0518119579ede19228ba5c0668a9c06c915510b95585216ef
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM23 MYO10 FAT4 PCDHGA2 FAM171A1 OIT3 HMCN1

1.53e-0518119574df7972f88117108698efd06b124b232f8588981
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_IL7R|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO10 HPSE2 GPR63 TEX26 GPD2 FRAS1 CACHD1

1.53e-051811957b9fe3833a6a56b9fbe5c257393fdbea5bf8ac4a3
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP3 ADAM23 PFKFB3 FRAS1 CWH43 KIF26B SUSD1

1.53e-051811957b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM23 MYO10 FAT4 PCDHGA2 FAM171A1 OIT3 HMCN1

1.53e-051811957cbb530566893281289026bfd93adf721decd4ca3
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GPR37L1 TMEM132C PCDH15 OLIG1 IFI44 CSPG4 TNR

1.59e-051821957a05e5978ef5f7fac7eeb2ba1c0103ea90d5e9136
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA2D2 TMEM132C PCDH15 NOS1 KIF26B PCSK6 TENM1

1.59e-051821957a3c5c0eff527c8d3848acda14af8f9e99c69b0de
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GPR37L1 TMEM132C PCDH15 OLIG1 IFI44 CSPG4 TNR

1.59e-0518219573cc61f5f7ad4a81eba3daf65e122880b5af3adc0
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GPR37L1 TMEM132C PCDH15 OLIG1 IFI44 CSPG4 TNR

1.59e-051821957831b5ce46b41efe01c4db6016c2f43148611373d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GPR37L1 TMEM132C PCDH15 OLIG1 IFI44 CSPG4 TNR

1.59e-0518219575d909e4b5f662905bf1be9c686bbddc3e87d2be9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CNNM2 FRAS1 CWH43 CACHD1 XKR6 FAM171A1 HMCN1

1.65e-0518319572e831a4d99c6f983793df71c0994124c943c6da9
ToppCelldroplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR37L1 SYNDIG1 GOT1L1 FAT3 SPAG6 SLC5A1 TENM1

1.71e-0518419576388c47b7f1d8203e3069eba0e74107256dcae51
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

DOCK4 TLR7 COL14A1 FAT4 HMCN1 PCDHGA12 PCDH9

1.71e-05184195767164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCelldroplet-Heart-4Chambers-18m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR37L1 SYNDIG1 GOT1L1 FAT3 SPAG6 SLC5A1 TENM1

1.71e-051841957d83ae1dc64aa1b27d3b524c137567418cc0ff8c6
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GPR37L1 TMEM132C PCDH15 OLIG1 IFI44 CSPG4 TNR

1.77e-0518519572e1766f1a972fecd670daaaf7eb2d3a404f121e7
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GPR37L1 TMEM132C PCDH15 OLIG1 IFI44 CSPG4 TNR

1.77e-0518519577aaa8335b40927e3e8fdcede807cd521fc213a0d
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GPR37L1 TMEM132C PCDH15 OLIG1 IFI44 CSPG4 TNR

1.77e-051851957fba2dc46cd98ab9c78e788959c2121aa10d148b2
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TEX26 DNAH6 LMNTD1 DRC7 DNAH2 SPAG6 DNAH12

1.77e-0518519573e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

DNAH6 LMNTD1 DRC7 DNAH2 MUC16 SPAG6 DNAH12

1.77e-05185195718a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GPR37L1 TMEM132C PCDH15 OLIG1 IFI44 CSPG4 TNR

1.77e-051851957efc5d564f8793c751ba640aef60f761e4b081d3f
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TEX26 DNAH6 LMNTD1 DRC7 DNAH2 SPAG6 DNAH12

1.83e-05186195785787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCellSubstantia_nigra-Neuronal-Inhibitory|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CACNA2D2 TTC3 PGR KIF26B OPRK1 PTPN5 ELAVL4

1.83e-0518619579d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMEM132C XKR7 PCDH15 COL14A1 FAT3 PTPN5

1.88e-051251956b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GPR37L1 TMEM132C PCDH15 OLIG1 IFI44 CSPG4 TNR

1.89e-0518719575b7a1edee602e55d3400dc17dbb6b8aaa26defc0
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GPR37L1 TMEM132C PCDH15 OLIG1 IFI44 CSPG4 TNR

1.89e-051871957daff7ccd3f1924cf2b34d3aca3eccde245aaf371
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CACNA2D2 TTC3 PGR KIF26B OPRK1 PTPN5 ELAVL4

1.96e-051881957b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CNNM2 SLC22A15 NOS1 PKP4 CACHD1 XKR6 HMCN1

1.96e-051881957bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CNNM2 SLC22A15 NOS1 PKP4 CACHD1 XKR6 HMCN1

1.96e-051881957eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRINP3 GPR37L1 PCDH15 ST8SIA1 CSPG4 ELAVL4 TNR

1.96e-051881957a244fcd092d5bd544e503366b1439b0fbc1ee00e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRINP3 GPR37L1 PCDH15 ST8SIA1 CSPG4 ELAVL4 TNR

1.96e-051881957c8530c9ff98666c64a94683261af4288cb790a7e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CNNM2 SLC22A15 NOS1 PKP4 FAM171A1 HMCN1 PCDH9

2.03e-051891957f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO10 TMEM132C PCDH15 COL14A1 KIF26B FAT3 ST8SIA1

2.03e-0518919572a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPR37L1 TMEM132C PCDH15 OLIG1 NOS1 CSPG4 TNR

2.10e-0519019576c7e1086c0a274cd5527c3104106e372811c9905
ToppCell(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

DOCK4 MYO10 SMPDL3A COL14A1 FRAS1 FAT3 HMCN1

2.10e-05190195771e112dfb8c3190fe0286b45a046ea789eb6a8db
DrugAC1NFC6P

MYO10 HCFC2 OLIG1 PCDHGA3 PCDHGA2 OPRK1 PCDHGA12 CSPG4 TNR PCDHGA8

5.61e-0714819310CID000004587
Drugthioridazine hydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A

BRINP3 NEDD4 LARP4B RBM14 CCDC15 GPD2 PKP4 ARMC9 PCSK6 EML1 PCDH9

1.07e-06198193116989_DN
Diseasemental development measurement

PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 PCDHGA8

2.51e-12251908EFO_0008230
DiseaseSarcosine measurement

PCDHGB1 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 PCDHGA8

9.23e-11231907EFO_0021668
Diseasechildhood trauma measurement, alcohol consumption measurement

PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 PCDHGA12 PCDHGA8

8.31e-10711909EFO_0007878, EFO_0007979
DiseaseUsher syndrome, type 1A

MYO7A CDH23 PCDH15

2.60e-0651903C2931205
DiseaseUSHER SYNDROME, TYPE IB (disorder)

MYO7A CDH23 PCDH15

2.60e-0651903C1848638
DiseaseUSHER SYNDROME, TYPE IA, FORMERLY

MYO7A CDH23 PCDH15

2.60e-0651903C1848639
DiseaseUSHER SYNDROME, TYPE I, FRENCH VARIETY, FORMERLY

MYO7A CDH23 PCDH15

2.60e-0651903C1848640
DiseaseUsher syndrome type 1

MYO7A CDH23 PCDH15

2.60e-0651903cv:C1568247
DiseaseGeneralized seizures

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.24e-061011907C0234533
DiseaseClonic Seizures

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.24e-061011907C0234535
DiseaseConvulsive Seizures

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.24e-061011907C0751494
DiseaseSeizures, Sensory

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.24e-061011907C0751496
DiseaseNon-epileptic convulsion

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.24e-061011907C0751056
DiseaseAtonic Absence Seizures

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.24e-061011907C0751123
DiseaseComplex partial seizures

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.24e-061011907C0149958
DiseaseSingle Seizure

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.24e-061011907C0751110
DiseaseNonepileptic Seizures

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.24e-061011907C3495874
DiseaseVisual seizure

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.24e-061011907C0270824
DiseaseEpileptic drop attack

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.24e-061011907C0270846
DiseaseVertiginous seizure

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.24e-061011907C0422855
DiseaseGustatory seizure

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.24e-061011907C0422854
DiseaseSeizures, Somatosensory

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.24e-061011907C0422850
DiseaseOlfactory seizure

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.24e-061011907C0422853
DiseaseSeizures, Auditory

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.24e-061011907C0422852
DiseaseGeneralized Absence Seizures

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.24e-061011907C4505436
DiseaseJacksonian Seizure

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.24e-061011907C0022333
DiseaseEpileptic Seizures

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.24e-061011907C4317109
DiseaseAbsence Seizures

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.53e-061021907C4316903
DiseaseConvulsions

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.53e-061021907C4048158
DiseaseTonic Seizures

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

4.53e-061021907C0270844
DiseaseSeizures, Focal

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

5.15e-061041907C0751495
DiseaseMyoclonic Seizures

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

5.15e-061041907C4317123
DiseaseTonic - clonic seizures

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 OPRK1

5.15e-061041907C0494475
DiseaseUsher Syndrome, Type I

MYO7A CDH23 PCDH15

5.18e-0661903C1568247
DiseaseHereditary retinal dystrophy

MYO7A CDH23 PCDH15

9.02e-0671903C0154860
DiseaseUsher syndrome

MYO7A CDH23 PCDH15

9.02e-0671903cv:C0271097
Diseaseaspartate aminotransferase measurement

PLB1 CACNA2D2 MYO7A HPSE2 PTBP1 LPIN1 CLCN4 ABCC2 HEPHL1 ABCG8 DNAH2 MANEA R3HDM2 ARMC9 XKR6 SLC2A4 APOL3 MYO15A

2.43e-0590419018EFO_0004736
DiseaseUsher syndrome, type 1D

CDH23 PCDH15

4.12e-0521902C2931208
DiseaseUSHER SYNDROME, TYPE ID

CDH23 PCDH15

4.12e-0521902C1832845
DiseaseUSHER SYNDROME, TYPE ID

CDH23 PCDH15

4.12e-0521902601067
DiseaseUsher syndrome type 1D

CDH23 PCDH15

4.12e-0521902cv:C1832845
DiseaseUsher syndrome type 1D (is_implicated_in)

CDH23 PCDH15

4.12e-0521902DOID:0110831 (is_implicated_in)
DiseaseSeizures

CNNM2 SYN2 ALAD ABCC2 NOS1 DRD3 SLC35A1 OPRK1

8.97e-052181908C0036572
Diseasemean platelet volume

GALK2 ATAD5 NFASC PLXND1 CDIPT ABCG8 PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 STXBP5 PCDHGA3 PCDHGA2 PCDHGA12 MCM9 CKAP2L PCDHGA8

1.14e-04102019018EFO_0004584
DiseaseNonsyndromic Deafness

MYO7A CDH23 PCDH15 TGFB3 MYO15A

1.81e-04811905C3711374
Diseaselymphocyte count

IRAK1 CDH23 PLXND1 PFKFB3 FOCAD NFIX SYN2 PPP2R3C FRAS1 PCDHGB1 PCDHGA9 PCDHGA7 PCDHGA6 PCDHGA4 PCDHGA3 PCDHGA2 IFI44 SLFN12L PCDHGA12 PRF1 CDC5L PCDHGA8

2.00e-04146419022EFO_0004587
DiseaseUsher Syndrome

MYO7A PCDH15

2.45e-0441902C0271097
DiseaseKidney Diseases

CNNM2 ALAD LCN2 LRP2 SMPD1

2.67e-04881905C0022658
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

MYO7A CDH23 PCDH15 MYO15A

3.29e-04511904cv:CN043650
Diseasenervous system disorder

ABCC2 NOS1 SLC19A1 GUSB

3.81e-04531904C0027765
Diseasetransmembrane protein 132C measurement

TMEM132C MGAT3

4.07e-0451902EFO_0802152
DiseaseUsher Syndrome, Type II

MYO7A PCDH15

4.07e-0451902C1568249
Diseasehearing impairment

CACNA2D2 MYO7A CDH23 PCDH15 MYO15A

4.39e-04981905C1384666
Diseaseamino acid measurement

PXDN COL14A1 C5 MGAM2 FAT4 ST8SIA1 CLDN23 SLC2A4 DNAH12 SUSD1 PCSK6 MCM9 LRP2

4.82e-0467819013EFO_0005134
Diseaseresponse to opioid

TMEM132C MUC16 TNR PCDH9

6.53e-04611904EFO_0008541
DiseaseArrhythmogenic right ventricular cardiomyopathy

DSG2 TGFB3

8.48e-0471902cv:C0349788
DiseaseUsher Syndrome, Type III

MYO7A PCDH15

8.48e-0471902C1568248
DiseaseCholestasis of pregnancy

ABCC2 ABCG8

1.13e-0381902C0268318
Diseaseasthma, endometriosis

C5 XKR6 CLDN23 CDK2AP1

1.35e-03741904EFO_0001065, MONDO_0004979
DiseaseAbnormality of refraction

PTBP1 ZNF891 NEDD4 NFIX ASCC2 GPD2 SEMA4D FAT3 ST8SIA1 MON1A PTPN5 PCDH9

1.47e-0367319012HP_0000539
DiseaseNonsyndromic genetic hearing loss

MYO7A CDH23 PCDH15 MYO15A

1.49e-03761904cv:C5680182
Diseaseserum alanine aminotransferase measurement

IRAK1 PTBP1 SYN2 ABCC2 HEPHL1 ABCG8 DNAH2 XKR6 CLDN23 SLC2A4 CDK2AP1 FAM222B MCM9 APOL3

1.58e-0386919014EFO_0004735
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

STUB1 EML3 EML1

1.60e-03361903DOID:11723 (implicated_via_orthology)
Diseaseshort-term memory

PCDH15 DNAH12 MCM9 CKAP2L

2.06e-03831904EFO_0004335
Diseasehemoglobin A1 measurement

CNNM2 CACUL1 PLXND1 PTBP1 UBE2V2 ASCC2 SYN2 ARHGAP25 SLC19A1 APOL3

2.10e-0352019010EFO_0007629
DiseaseSCHIZOPHRENIA

SYN2 DRD3

2.18e-03111902181500
Diseaseresponse to simvastatin, myopathy

KIAA1328 XKR6 CSPG4

2.34e-03411903EFO_0004145, GO_1903491
DiseaseDrug-induced agranulocytosis, response to clozapine

NFASC CLDN23 FAM171A1

2.51e-03421903GO_0097338, HP_0012235
DiseaseClear Cell Meningioma

PGR ALAD

2.61e-03121902C0431121
DiseaseIntraventricular Meningioma

PGR ALAD

2.61e-03121902C1334271
DiseaseBenign Meningioma

PGR ALAD

2.61e-03121902C0281784
DiseaseIntraorbital Meningioma

PGR ALAD

2.61e-03121902C1334261
DiseaseOlfactory Groove Meningioma

PGR ALAD

2.61e-03121902C1335107
DiseaseAngioblastic Meningioma

PGR ALAD

2.61e-03121902C1527197
DiseaseMeningiomas, Multiple

PGR ALAD

2.61e-03121902C0205834
DiseaseXanthomatous Meningioma

PGR ALAD

2.61e-03121902C0457190
DiseaseAngiomatous Meningioma

PGR ALAD

2.61e-03121902C0334608
DiseasePsammomatous Meningioma

PGR ALAD

2.61e-03121902C0334607
DiseaseFibrous Meningioma

PGR ALAD

2.61e-03121902C0334606
DiseaseMeningothelial meningioma

PGR ALAD

2.61e-03121902C0334605
DiseaseHemangioblastic Meningioma

PGR ALAD

2.61e-03121902C0334609
DiseaseTransitional Meningioma

PGR ALAD

2.61e-03121902C0334611
DiseaseHemangiopericytic Meningioma

PGR ALAD

2.61e-03121902C0334610
DiseaseSpinal Meningioma

PGR ALAD

2.61e-03121902C0347515
DiseaseIntracranial Meningioma

PGR ALAD

2.61e-03121902C0349604
DiseasePapillary Meningioma

PGR ALAD

2.61e-03121902C3163622
DiseaseMalignant Meningioma

PGR ALAD

2.61e-03121902C0259785
DiseaseSphenoid Wing Meningioma

PGR ALAD

2.61e-03121902C1565951
DiseasePosterior Fossa Meningioma

PGR ALAD

2.61e-03121902C1565950
DiseaseParasagittal Meningioma

PGR ALAD

2.61e-03121902C0751304
DiseaseCerebral Convexity Meningioma

PGR ALAD

2.61e-03121902C0751303
DiseaseMicrocystic meningioma

PGR ALAD

2.61e-03121902C1384408
DiseaseSecretory meningioma

PGR ALAD

2.61e-03121902C1384406
Diseasecortical surface area measurement

CNNM2 PLXND1 ZNF891 FOCAD NFIX IGSF9 OLIG1 SEMA4D KIF26B FAT3 HIPK2 CACHD1 XKR6 CLDN23 STRIP1 TREH EML1 CDC5L

2.78e-03134519018EFO_0010736
DiseaseIGFBP-1 measurement

MYO10 ELAVL4

3.07e-03131902EFO_0005118
Diseaseselective IgA deficiency disease

CDH23 PFKFB3 FAM171A1

3.25e-03461903EFO_1001929
Diseaseend stage renal disease (biomarker_via_orthology)

LPIN1 NOS1 LRP2

3.46e-03471903DOID:783 (biomarker_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

CACNA2D2 NFASC SYN2 NOS1 KCNH5

4.17e-031631905DOID:1826 (implicated_via_orthology)
DiseaseInfluenza

IFIT5 SLC22A8 IFI44

4.61e-03521903C0021400
DiseaseAlzheimer disease, polygenic risk score

PXDN UBE2V2 ASCC2 FRAS1 PCDHGB1 PCDHGA4 PCDHGA3 PCDHGA2 SPAG6 FAM171A1

4.88e-0358619010EFO_0030082, MONDO_0004975

Protein segments in the cluster

PeptideGeneStartEntry
ALNTTATYAEPYRPI

PKP4

471

Q99569
LILIRYTGDNSPYSP

ABHD13

101

Q7L211
YVGNRQASIIEYLPT

ATAD5

1786

Q96QE3
RDLILQLDYPYTQGS

BRINP3

681

Q76B58
YAGSVRTLQPPDIYS

BAHCC1

1926

Q9P281
SQVLYLPGQSRYTRA

CDC5L

666

Q99459
GTLQLRYQLGTSPYV

CNTNAP1

1116

P78357
ITLPSRLIYYINQDS

ADAM23

111

O75077
TDAYLLYTPSQIALT

CCNH

201

P51946
ATEPYNAARPYSVAL

CSPG4

2161

Q6UVK1
RSTNYSLGLVLPPYS

CACNA2D2

631

Q9NY47
QLLYRARETYGLPNT

SMPD1

536

P17405
TRLQISQDPSLNYEY

GOT1L1

56

Q8NHS2
QQPSYYSDLDETLPT

ASCC2

186

Q9H1I8
PNSYIEYTLLNPLGN

FAT4

2081

Q6V0I7
YTAYLSDNTRLIANP

CACHD1

681

Q5VU97
LYFTYSGQPNTLEVR

ABCG8

36

Q9H221
LLSQLYQSPNRRYPG

ELAVL4

226

P26378
AIIAYPNPYTRQSTS

CLCN4

381

P51793
SGNPVLRIYYTSRPA

CDIPT

126

O14735
PLDYEQISNGLIYLT

CDH23

626

Q9H251
QLLTQSPGDYIPISY

CACUL1

146

Q86Y37
GYRSYLRPITQAPSE

DENND4A

576

Q7Z401
RYSLLGQPLQYNLSI

R3HDM2

806

Q9Y2K5
QDLARSYGIPYIETS

HRAS

131

P01112
YVAPLTAQPATYRAQ

RBM14

226

Q96PK6
YRQNVYIPGSNATLT

PCDHGA7

891

Q9Y5G6
YRQNVYIPGSNATLT

PCDHGA2

891

Q9Y5H1
YRQNVYIPGSNATLT

PCDHGA8

891

Q9Y5G5
YRQNVYIPGSNATLT

PCDHGA12

891

O60330
PDDPLSSYINANYIR

PTPN5

346

P54829
TLRNYLPPVYSQRGQ

MSGN1

146

A6NI15
SAPSALRVYGQYLNL

PPP2R3C

271

Q969Q6
PAYYDTRIGQILINI

ANKAR

136

Q7Z5J8
GSPLPRYLYLASNQT

AOC2

576

O75106
RVYAPASTLVDQPYA

DSG2

966

Q14126
YRQNVYIPGSNATLT

PCDHGA4

921

Q9Y5G9
YYPNNETESILGRII

TENT4B

401

Q8NDF8
ELGPYTLDRNSLYVN

MUC16

12331

Q8WXI7
ELGPYTLDRNSLYVN

MUC16

12956

Q8WXI7
YRQNVYIPGSNATLT

PCDHGA6

891

Q9Y5G7
EPRAPDSTAYTQLVY

FAM171A1

776

Q5VUB5
AYNNQISYLPPSLLS

LRRD1

681

A4D1F6
PSYYNINQVTLGRRS

NFIX

251

Q14938
QLNYLPSYGTLLRIS

FRAS1

1751

Q86XX4
SPTLYIRLVQDYGLE

GPD2

476

P43304
LITRAPATYQALYQR

GPR88

141

Q9GZN0
RYISQTQGLPAEYLL

HIPK2

411

Q9H2X6
SILNYPSTLYQPSAA

HIPK2

611

Q9H2X6
YLLQLSTDLPYQAAS

HCFC2

386

Q9Y5Z7
LQPTRYSGYLQSSNV

NEDD4

91

P46934
LSISTRLPSQYIYGF

MGAM2

1076

Q2M2H8
YLLDNPYQEPRSTAA

MGAT3

496

Q09327
AQRYADFTLLSIPYP

MTMR14

236

Q8NCE2
TQRPTANSSYPYVEI

MYO15A

3466

Q9UKN7
SPRYLYIIQNLEGPA

SLC2A4

226

P14672
IRYISQTQGLPAEYL

HIPK1

401

Q86Z02
GADIIITYYTPQLLQ

ALAD

311

P13716
PNLRIISLNTNLYYG

SMPDL3A

201

Q92484
YVNGALYSILSVPSI

ARMC9

521

Q7Z3E5
YLVPSLTRYLTLNAS

ERVMER34-1

321

Q9H9K5
LSRTNGVTLYPYQIS

KIF26B

321

Q2KJY2
QLALSIGTPYRYNTS

KCNH5

391

Q8NCM2
PLDVSLYAQQRYATS

LARP4B

326

Q92615
SLGIRPNYIDIYSAS

PCSK6

291

P29122
VYYLTLQLDTQLTSP

PLXNA1

256

Q9UIW2
DRANISSPGLIYTYT

PLXNA3

1006

P51805
LYEERYVLPSQTLNS

PLXND1

1366

Q9Y4D7
TRYITERNYPSRQGP

LCTL

346

Q6UWM7
LQGEYPPQLSYTELA

LHX9

191

Q9NQ69
LYTISEGYVPNLRNS

OIT3

361

Q8WWZ8
YRQNVYIPGSNATLT

PCDHGA9

891

Q9Y5G4
YRQNVYIPGSNATLT

PCDHGB1

886

Q9Y5G3
RYIISPINGTVYLSE

PCDH9

361

Q9HC56
ASTQPAYLRLISNYG

PRF1

206

P14222
LDTSAQRYSPYPTQA

FAM222B

81

Q8WU58
RYPTGESYQDLVQRL

PFKFB3

356

Q16875
TYALQLANTNPLYPD

GALK2

76

Q01415
AYEYLGNSPRLVITP

DNAH12

1216

Q6ZR08
QIYTYIGSILASVNP

MYO10

91

Q9HD67
NLSLAVIYPQSASYP

LPIN1

216

Q14693
LGYYLSSPQISRVTI

LMNTD1

46

Q8N9Z9
VPAVRYTNPSLYLGT

ABCC2

96

Q92887
PTGLSIDYLNNDRIY

LRP2

4231

P98164
TRLYYETPRFTVLNQ

CYHR1

246

Q6ZMK1
QPIRIYSRASLYGPN

HPSE2

291

Q8WWQ2
TQTVRGTLAYLPEEY

IRAK1

381

P51617
SLYELVGYRQPPSSS

OLIG1

31

Q8TAK6
RVSYVNSVPLLSYLI

OOSP4A

156

A0A2R8YFL7
DYNQLRPLSYPNTDV

RHOJ

81

Q9H4E5
ELDGSYLSIARPQTY

KIAA1328

206

Q86T90
KIRNISYTPYDLPGN

LRRC58

271

Q96CX6
YYEIGLSAALQTRPS

MANEA

381

Q5SRI9
EYNLQVYIRPTITNS

HMCN1

2281

Q96RW7
QLSLLQPRYYSISSS

NOS1

1171

P29475
LRLASSVTYNAYIQP

PRSS41

151

Q7RTY9
YRQNVYIPGSNATLT

PCDHGA3

891

Q9Y5H0
PGLTSYLVRVVSTNY

LCN2

121

P80188
YLNYLRPDSEASQSP

PGR

541

P06401
NASRPLKTIYYTGPN

MON1A

586

Q86VX9
YPGSVNSAVLRLSPY

NFASC

681

O94856
VNGPLDYETRTSYVL

PCDH15

1091

Q96QU1
ENYATYSPLSSQPVL

CCNYL3

226

P0C7X3
PLDYYRVNLTGTIQL

GALE

101

Q14376
GINDPVIYSISYSTR

CDHR2

271

Q9BYE9
PAVPRSSIEYDTYNL

DNAH6

206

Q9C0G6
ILYIVASDPYSRISQ

HECTD1

2006

Q9ULT8
LSALRTYEPYGSLVQ

IFI44

171

Q8TCB0
TYEPYGSLVQQIRIL

IFI44

176

Q8TCB0
ILDQISSQPYVLRYA

IFIT5

241

Q13325
VESQLYTNPDSRYIL

DOCK4

816

Q8N1I0
YFSALPSQLYQLPDE

CDK15

386

Q96Q40
LRYADGPQLYITEQT

ELMO2

51

Q96JJ3
RAITRNPLVAVYYTN

STUB1

51

Q9UNE7
LSGLLPNTEYTVTVY

COL14A1

501

Q05707
IQNPLYPVTESSYSA

GPR37L1

116

O60883
TSYIINNLQPDTTYR

FNDC3A

911

Q9Y2H6
DLSRGYQETLPSYAQ

GJA8

311

P48165
YAGLQRSVLLYTTPT

GUSB

211

P08236
RPAYLYSLEVQLTAQ

GUSB

296

P08236
PSSRLLVYYIVTGEQ

C5

536

P01031
QLIYESYVSELAPRG

FAT3

2396

Q8TDW7
PTVQLRSANGYYLSQ

FSCN3

306

Q9NQT6
TSSQYRQLLSDYGPP

CDK2AP1

31

O14519
GYRTYLRPITEAPSN

DENND4C

576

Q5VZ89
RDITPNLLSLLNNYY

APOL3

271

O95236
PYLNSNGLVSRLTTY

DRC7

451

Q8IY82
TTYTVLRNIDNRIPY

HEPHL1

1061

Q6MZM0
YYVLQLTQLSISRPT

MCHR1

341

Q99705
NPGYQAYVILISLIS

GPR63

236

Q9BZJ6
PSLILYLNDTSAQAY

GDF9

261

O60383
NNLYLLPTGETVYFI

EML1

236

O00423
EQLSVVRYSPDGLYL

EML3

681

Q32P44
SEDISQYYIGPLRIS

CCDC168

2926

Q8NDH2
LTLERTINLYPLTNY

NUDT21

31

O43809
PTVDTVRYNYLVSSL

DNAH2

2391

Q9P225
LYTSELYPTVIRQTG

SLC22A8

431

Q8TCC7
YTSELYPTVIRNVGL

SLC22A15

421

Q8IZD6
PVTVQVSYSLVLGYL

CLDN23

151

Q96B33
SLPQNPDYLQYSIST

CDC37L1

301

Q7L3B6
QSRASVPTDYSYLPE

FOCAD

1346

Q5VW36
LGYVNSALNPVIYTT

DRD3

371

P35462
TYQYPRAILSVDLSG

PHF20L1

621

A8MW92
FVVLSNGILYQYPDR

PLEKHM2

796

Q8IWE5
NGILYQYPDRTDVIP

PLEKHM2

801

Q8IWE5
IALGYTNSSLNPILY

OPRK1

316

P41145
TYRASLPYSQISGLN

PIGS

41

Q96S52
PTLSDVGNQVLLRYY

MCM9

536

Q9NXL9
YITSAPGSRDYLQLT

CWH43

581

Q9H720
QYAGLPSINSLESIY

SYN2

206

Q92777
YLYGLPRQDTTSIQQ

SLC35A1

311

P78382
YLGPLQVAYRETILN

GFM2

556

Q969S9
YSLVNRLYPDVGQLI

SESN1

361

Q9Y6P5
PGYSDTLLQRVDSYQ

SPAG6

491

O75602
TYKTRQPPVLNASYG

TMEM132C

86

Q8N3T6
QSVESRYRPNIILYS

SYNDIG1

81

Q9H7V2
IISNEVLLSLPRNYY

LMBR1L

86

Q6UX01
YNSQYLLRPAANVTP

RGPD2

876

P0DJD1
AETLYQGLLPSLPQY

STRIP1

506

Q5VSL9
PSLRVYYTLSDVGAN

ST8SIA1

231

Q92185
SRYNEVNITYSPSGL

TENM1

1836

Q9UKZ4
SIGPLVYSDQYLQIS

SI

216

P14410
VYSDQYLQISTRLPS

SI

221

P14410
YIRVLQPLSATSLYV

SEMA4D

111

Q92854
LPDVTTQYRGLSYSA

PLB1

761

Q6P1J6
YLVSPTEIQRLTYSQ

STXBP5

1006

Q5T5C0
ERILLTLVANPYSYT

URB1

701

O60287
YLVSPTEIQRLTYSQ

STXBP5L

1041

Q9Y2K9
VPLAYDRYQSGLSTE

CCDC15

736

Q0P6D6
TKPRTYPSLLQGEYN

CKAP2L

331

Q8IYA6
QLNSSLLQVYIPDYS

CNNM2

781

Q9H8M5
YYPTRLAINLSSGVS

GTF2H4

281

Q92759
VYAALGLSPSQTYIV

PITPNM1

1131

O00562
NILQYVTPTAVGIRY

XKR6

611

Q5GH73
QSLYYSLIFLNPTLD

RNFT1

226

Q5M7Z0
VYTAILSYSIQDLLP

ZNF678

26

Q5SXM1
LEYSSPATPRLQYRS

XKR7

551

Q5GH72
SSPVSQSYPLREYIN

SLFN12L

376

Q6IEE8
RNLPSSLEYLLLSYN

TLR9

216

Q9NR96
STRDPYATITYNVPE

SAGE1

241

Q9NXZ1
LENTRYQLYTGAEPT

SRL

116

Q86TD4
LYPTTDYTVNVTLLR

SUSD1

461

Q6UWL2
QLSILPRDNYSLLSY

ARHGAP25

276

P42331
NEITPVLSYSYLAVL

SLC19A1

66

P41440
SVYPREQINQLTSYI

PXDN

896

Q92626
LSQYSVQALRPGSRY

TNR

556

Q92752
DNRILTYQYGIPTSL

TREH

441

O43280
VSQGYSYLPVQLLAS

TMEM38B

101

Q9NVV0
GLPQYTSIYTPLASL

TTC3

1341

P53804
LFLIYYISTQQAPSE

SCFD1

456

Q8WVM8
PSASAYLTVLYPAQV

IGSF9

311

Q9P2J2
TVLPSTLTELYLYNN

TLR7

221

Q9NYK1
IGPPRTNYENRIYSL

UBE2V2

51

Q15819
LPSLALPLYQYASES

SRD5A1

61

P18405
VSNIYLSPRYLGNSP

PRSS21

121

Q9Y6M0
LGYTYSLSDPILNQT

TEX26

56

Q8N6G2
LEQIIGSVSNYPRYT

nan

61

Q6ZVU0
QLFDYIQSITSYLGP

SLC5A1

451

P13866
VPQLTYQLYVSLISA

XKRX

181

Q6PP77
VNYYTSVTPVLRGQP

PTBP1

111

P26599
PYQVLALYNSTRELL

TGFB3

66

P10600
SVEYQLYRLTVISPL

ZNF891

81

A8MT65
SEQYRQVASPRTDPY

ZIC2

191

O95409
SPINEILRRYSLYTN

nan

36

Q8N402
TYTGSILVAVNPYQL

MYO7A

96

Q13402