Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR2A14 OR8D1 OR2L8 ADGRG3 OR2A7 OR2L3 GPR50 HTR6 OR7A5 OR9I1 OR2W1 ADGRG1 GPR101 GRM2 GRM3 GRM5 GRM6 GRM7 F2RL2 ADGRA2 TAAR6 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 OR1P1 MRGPRX3 OR2A25 TAS2R31 TAS2R43 TAS2R19 TAS2R46 OR51V1 GPR176 OR9A2 OR2A2

4.92e-1988414037GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR2A14 FLT1 OR8D1 OR2L8 ADGRG3 OR2A7 OR2L3 GPR50 HTR6 OR7A5 OR9I1 OR2W1 ADGRG1 GRIK5 GPR101 GRM2 GRM3 GRM5 GRM6 GRM7 F2RL2 ADGRA2 PTPRT TAAR6 LRP8 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 OR1P1 MRGPRX3 OR2A25 HTR3B TAS2R31 TAS2R43 TAS2R19 TAS2R46 OR51V1 GPR176 EPHA10 PLXNB1 OR9A2 OR2A2

1.64e-18135314044GO:0004888
GeneOntologyMolecularFunctionolfactory receptor activity

OR2A14 OR8D1 OR2L8 OR2A7 OR2L3 OR7A5 OR9I1 OR2W1 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 OR1P1 OR2A25 OR51V1 OR9A2 OR2A2

1.38e-0943114018GO:0004984
GeneOntologyMolecularFunctionG protein-coupled glutamate receptor activity

GRM2 GRM3 GRM5 GRM6 GRM7

1.94e-0991405GO:0098988
GeneOntologyMolecularFunctionadenylate cyclase inhibiting G protein-coupled glutamate receptor activity

GRM2 GRM3 GRM5 GRM6 GRM7

1.94e-0991405GO:0001640
GeneOntologyMolecularFunctionglutamate receptor activity

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

2.80e-08271406GO:0008066
GeneOntologyMolecularFunctiontransmembrane transporter activity

GPM6A SLC26A3 CYBRD1 TMC2 SLC37A3 SLC43A1 TRPM2 SLC6A19 SIDT1 SLC13A3 GRIK5 SLC44A4 MFSD4B GRM7 TMC3 SLC40A1 SLC30A6 ITPR2 SLC6A12 SLC6A13 ATP11B NALCN HTR3B MFSD1 SLC23A1 ABCG5 MFSD10

4.40e-08118014027GO:0022857
GeneOntologyMolecularFunctiontransporter activity

GPM6A SLC26A3 CYBRD1 TMC2 SLC37A3 SLC43A1 TRPM2 SLC6A19 SIDT1 SLC13A3 GRIK5 SLC44A4 MFSD4B GRM7 TMC3 SLC40A1 SLC30A6 ITPR2 SLC6A12 SLC6A13 ATP11B NALCN HTR3B MFSD1 SLC23A1 ABCG5 MFSD10

2.62e-07128914027GO:0005215
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC26A3 SLC37A3 SLC6A19 SLC13A3 SLC44A4 MFSD4B SLC30A6 SLC6A12 SLC6A13 MFSD1 SLC23A1

7.86e-0629614011GO:0015291
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

GPM6A TMC2 TRPM2 SLC13A3 GRIK5 GRM7 SLC40A1 SLC30A6 ITPR2 SLC6A12 SLC6A13 NALCN SLC23A1

2.45e-0546514013GO:0046873
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC26A3 CYBRD1 SLC37A3 SLC6A19 SLC13A3 SLC44A4 MFSD4B SLC30A6 SLC6A12 SLC6A13 MFSD1 SLC23A1 ABCG5

3.20e-0547714013GO:0022804
GeneOntologyMolecularFunctionbitter taste receptor activity

TAS2R31 TAS2R43 TAS2R19 TAS2R46

3.58e-05271404GO:0033038
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

GPM6A SLC26A3 TMC2 TRPM2 SLC13A3 GRIK5 GRM7 TMC3 SLC40A1 SLC30A6 ITPR2 SLC6A12 SLC6A13 ATP11B NALCN HTR3B SLC23A1

4.13e-0579314017GO:0015075
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC26A3 SLC37A3 SLC43A1 SLC13A3 GRIK5 SLC44A4 SLC6A12 SLC6A13 SLC23A1 MFSD10

4.25e-0529314010GO:0008514
GeneOntologyMolecularFunctiongroup II metabotropic glutamate receptor activity

GRM2 GRM3

4.88e-0521402GO:0001641
GeneOntologyMolecularFunctionmedium-chain fatty acid-CoA ligase activity

AACS ACSM2A ACSM2B

5.34e-05111403GO:0031956
GeneOntologyMolecularFunctiontaste receptor activity

TAS2R31 TAS2R43 TAS2R19 TAS2R46

8.09e-05331404GO:0008527
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC43A1 SLC6A19 SLC13A3 GRIK5 SLC6A12 SLC6A13

9.72e-051051406GO:0015171
GeneOntologyMolecularFunctionorganic acid:sodium symporter activity

SLC13A3 SLC6A12 SLC6A13 SLC23A1

1.02e-04351404GO:0005343
GeneOntologyMolecularFunctionbenzoate-CoA ligase activity

ACSM2A ACSM2B

1.46e-0431402GO:0018858
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

TRPM2 SLC13A3 GRIK5 SLC6A12 SLC6A13 NALCN SLC23A1

2.06e-041711407GO:0015081
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

GPM6A TMC2 TRPM2 SLC13A3 GRIK5 GRM7 SLC40A1 SLC30A6 ITPR2 SLC6A12 SLC6A13 NALCN HTR3B SLC23A1

2.42e-0466414014GO:0008324
GeneOntologyMolecularFunctionprotein serine kinase activity

RPS6KA5 RPS6KA2 OBSCN MAPKAPK5 MKNK1 PIM3 RPS6KA6 PLK1 PLK4 PLK3

2.47e-0436314010GO:0106310
GeneOntologyMolecularFunctionodorant binding

OR8D1 OR2A7 OR9I1 LCN15 OR2A4 OR2A25

2.75e-041271406GO:0005549
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

GPM6A SLC26A3 TMC2 SLC37A3 TRPM2 SLC13A3 GRIK5 GRM7 SLC40A1 SLC30A6 ITPR2 SLC6A12 SLC6A13 NALCN SLC23A1

2.85e-0475814015GO:0015318
GeneOntologyMolecularFunctiongroup III metabotropic glutamate receptor activity

GRM6 GRM7

2.90e-0441402GO:0001642
GeneOntologyMolecularFunctiondecanoate-CoA ligase activity

ACSM2A ACSM2B

2.90e-0441402GO:0102391
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

MYLK RPS6KA5 RPS6KA2 OBSCN MAPKAPK5 MKNK1 PIM3 RPS6KA6 PLK1 PLK4 PLK3

3.13e-0444614011GO:0004674
GeneOntologyMolecularFunctionprotein kinase activity

FLT1 MYLK RPS6KA5 RPS6KA2 OBSCN MAPKAPK5 MKNK1 PIM3 RPS6KA6 PLK1 PLK4 PLK3 EPHA10

3.14e-0460014013GO:0004672
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

GPM6A TMC2 TRPM2 SLC13A3 GRIK5 GRM7 SLC40A1 SLC30A6 ITPR2 SLC6A12 SLC6A13 NALCN SLC23A1

4.76e-0462714013GO:0022890
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC26A3 SLC43A1 SLC13A3 GRIK5 SLC6A12 SLC6A13 SLC23A1

6.53e-042071407GO:0046943
GeneOntologyMolecularFunctionsymporter activity

SLC6A19 SLC13A3 MFSD4B SLC6A12 SLC6A13 SLC23A1

6.68e-041501406GO:0015293
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC26A3 SLC43A1 SLC13A3 GRIK5 SLC6A12 SLC6A13 SLC23A1

6.71e-042081407GO:0005342
GeneOntologyMolecularFunctiongamma-aminobutyric acid:sodium:chloride symporter activity

SLC6A12 SLC6A13

7.19e-0461402GO:0005332
GeneOntologyMolecularFunctionfatty acid ligase activity

AACS ACSM2A ACSM2B

7.79e-04261403GO:0015645
GeneOntologyMolecularFunctionCoA-ligase activity

AACS ACSM2A ACSM2B

8.72e-04271403GO:0016405
GeneOntologyMolecularFunctionsulfur compound transmembrane transporter activity

SLC26A3 SLC13A3 SLC44A4 SLC6A13

8.86e-04611404GO:1901682
GeneOntologyMolecularFunctionribosomal protein S6 kinase activity

RPS6KA2 RPS6KA6

1.00e-0371402GO:0004711
GeneOntologyMolecularFunctioncalmodulin binding

STRN3 MYLK MYO5B OBSCN GRM7 MAPKAPK5 MKNK1

1.21e-032301407GO:0005516
GeneOntologyMolecularFunctionacid-thiol ligase activity

AACS ACSM2A ACSM2B

1.31e-03311403GO:0016878
GeneOntologyMolecularFunctionfatty-acyl-CoA synthase activity

ACSM2A ACSM2B

1.33e-0381402GO:0004321
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

FLT1 MYLK RPS6KA5 RPS6KA2 OBSCN MAPKAPK5 MKNK1 PIM3 RPS6KA6 PLK1 PLK4 PLK3 EPHA10

1.47e-0370914013GO:0016773
GeneOntologyMolecularFunctiongamma-aminobutyric acid transmembrane transporter activity

SLC6A12 SLC6A13

1.70e-0391402GO:0015185
GeneOntologyMolecularFunctioncalcium-dependent protein serine/threonine kinase activity

MAPKAPK5 MKNK1

2.12e-03101402GO:0009931
GeneOntologyMolecularFunctioncalcium channel activity

GPM6A TMC2 TRPM2 GRM7 ITPR2

2.17e-031291405GO:0005262
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC13A3 SLC6A12 SLC6A13 SLC23A1

2.54e-03811404GO:0015370
GeneOntologyMolecularFunctionkinase activity

FLT1 MYLK RPS6KA5 RPS6KA2 OBSCN MAPKAPK5 MKNK1 PIM3 RPS6KA6 PLK1 PLK4 PLK3 EPHA10

2.82e-0376414013GO:0016301
GeneOntologyMolecularFunctionmonoatomic cation channel activity

GPM6A TMC2 TRPM2 GRIK5 GRM7 ITPR2 NALCN HTR3B

2.93e-033431408GO:0005261
GeneOntologyMolecularFunctionligase activity, forming carbon-sulfur bonds

AACS ACSM2A ACSM2B

2.96e-03411403GO:0016877
GeneOntologyMolecularFunctiontransition metal ion transmembrane transporter activity

TRPM2 SLC40A1 SLC30A6

3.62e-03441403GO:0046915
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

GPM6A TMC2 TRPM2 GRM7 ITPR2

4.26e-031511405GO:0015085
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR2A14 OR8D1 OR2L8 ADGRG3 OR2A7 OR2L3 GPR50 HTR6 OR7A5 OR9I1 OR2W1 ADGRG1 GPR101 GRM2 GRM3 GRM5 GRM6 GRM7 F2RL2 ADGRA2 TAAR6 GPR180 OR2A12 NPS OR51I1 OR2A4 OR1A1 OR2D3 OR1P1 MRGPRX3 OR2A25 TAS2R31 TAS2R43 TAS2R19 TAS2R46 OR51V1 GPR176 OR9A2 OR2A2

1.24e-14139514039GO:0007186
GeneOntologyBiologicalProcessdetection of stimulus

OR2A14 OR8D1 OR2L8 OR2A7 TMC2 OR2L3 OR7A5 TRA OR9I1 OR2W1 GRM6 NLRP3 NOD1 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 OR1P1 OR2A25 TAS2R31 TAS2R43 TAS2R19 TAS2R46 OR51V1 OR9A2 OR2A2

4.03e-1372214027GO:0051606
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR2A14 OR8D1 OR2L8 OR2A7 TMC2 OR2L3 OR7A5 OR9I1 OR2W1 GRM6 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 OR1P1 OR2A25 TAS2R31 TAS2R43 TAS2R19 TAS2R46 OR51V1 OR9A2 OR2A2

1.22e-1258214024GO:0050906
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR2A14 OR8D1 OR2L8 OR2A7 OR2L3 OR7A5 OR9I1 OR2W1 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 OR1P1 OR2A25 TAS2R31 TAS2R43 TAS2R19 TAS2R46 OR51V1 OR9A2 OR2A2

1.81e-1248514022GO:0050907
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR2A14 OR8D1 OR2L8 OR2A7 OR2L3 OR7A5 OR9I1 OR2W1 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 OR1P1 OR2A25 TAS2R31 TAS2R43 TAS2R19 TAS2R46 OR51V1 OR9A2 OR2A2

8.29e-1252414022GO:0009593
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR2A14 OR8D1 OR2L8 OR2A7 OR2L3 OR7A5 OR9I1 OR2W1 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 OR1P1 OR2A25 TAS2R31 TAS2R43 TAS2R19 TAS2R46 OR51V1 OR9A2 OR2A2

1.91e-1154714022GO:0007606
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR2A14 OR8D1 OR2L8 OR2A7 OR2L3 OR7A5 OR9I1 OR2W1 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 OR1P1 OR2A25 OR51V1 OR9A2 OR2A2

8.66e-1043214018GO:0050911
GeneOntologyBiologicalProcessadenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

GRM2 GRM3 GRM5 GRM6 GRM7

1.65e-0991405GO:0007196
GeneOntologyBiologicalProcesssensory perception of smell

OR2A14 OR8D1 OR2L8 OR2A7 OR2L3 OR7A5 OR9I1 OR2W1 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 OR1P1 OR2A25 OR51V1 OR9A2 OR2A2

2.77e-0946514018GO:0007608
GeneOntologyBiologicalProcesssensory perception

OR2A14 OR8D1 OR2L8 OR2A7 TMC2 OR2L3 OR7A5 OR9I1 OR2W1 GRM3 GRM6 GRM7 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 OR1P1 OR2A25 TAS2R31 TAS2R43 TAS2R19 TAS2R46 OR51V1 OR9A2 OR2A2

1.33e-08107214026GO:0007600
GeneOntologyBiologicalProcessG protein-coupled glutamate receptor signaling pathway

GRM2 GRM3 GRM5 GRM6 GRM7

5.52e-08161405GO:0007216
GeneOntologyBiologicalProcessglutamate receptor signaling pathway

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

2.94e-06591406GO:0007215
GeneOntologyBiologicalProcessadenylate cyclase-modulating G protein-coupled receptor signaling pathway

ADGRG3 HTR6 ADGRG1 GPR101 GRM2 GRM3 GRM5 GRM6 GRM7 GPR176

2.64e-0528614010GO:0007188
GeneOntologyBiologicalProcessadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

GRM2 GRM3 GRM5 GRM6 GRM7 GPR176

2.64e-05861406GO:0007193
GeneOntologyBiologicalProcesssynaptic transmission, glutamatergic

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7 NPS

3.32e-051321407GO:0035249
GeneOntologyBiologicalProcessregulation of synaptic transmission, glutamatergic

GRM2 GRM3 GRM5 GRM6 GRM7 NPS

3.88e-05921406GO:0051966
GeneOntologyBiologicalProcessorganic anion transport

SLC26A3 SLC37A3 HTR6 SLC43A1 SLC13A3 GRM2 SLC44A4 GRM7 SLC6A12 SLC6A13 G6PC3 SLC23A1 MFSD10

5.05e-0551514013GO:0015711
GeneOntologyBiologicalProcessamino acid transport

HTR6 SLC43A1 SLC6A19 SLC13A3 GRM2 GRM7 SLC6A12 SLC6A13

5.69e-051951408GO:0006865
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of bitter taste

TAS2R31 TAS2R43 TAS2R19 TAS2R46

2.24e-04441404GO:0001580
GeneOntologyBiologicalProcesspositive regulation of CREB transcription factor activity

RPS6KA5 LRP8 CD200

2.32e-04181403GO:0032793
GeneOntologyBiologicalProcessendoplasmic reticulum tubular network membrane organization

ATL1 ATL2

2.72e-0441402GO:1990809
GeneOntologyBiologicalProcessgamma-aminobutyric acid reuptake

SLC6A12 SLC6A13

2.72e-0441402GO:0051936
GeneOntologyBiologicalProcesssensory perception of bitter taste

TAS2R31 TAS2R43 TAS2R19 TAS2R46

3.14e-04481404GO:0050913
GeneOntologyBiologicalProcesstriglyceride homeostasis

DGAT2 ACSM2A FITM2 ABCG5

3.68e-04501404GO:0070328
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of taste

TAS2R31 TAS2R43 TAS2R19 TAS2R46

3.68e-04501404GO:0050912
GeneOntologyBiologicalProcessnegative regulation of amino acid transport

HTR6 SLC43A1 GRM7

3.72e-04211403GO:0051956
GeneOntologyBiologicalProcessmonoatomic ion transport

GPM6A SLC26A3 CYBRD1 TMC2 MYLK TRPM2 SLC6A19 SLC13A3 GRIK5 GRM6 MFSD4B TMC3 SLC40A1 SLC30A6 ITPR2 SLC6A12 SLC6A13 ATP11B NALCN HTR3B SLC23A1

3.88e-04137414021GO:0006811
GeneOntologyBiologicalProcessacylglycerol homeostasis

DGAT2 ACSM2A FITM2 ABCG5

3.97e-04511404GO:0055090
GeneOntologyBiologicalProcessendoplasmic reticulum tubular network organization

ATL1 TMEM33 ATL2

4.29e-04221403GO:0071786
GeneOntologyBiologicalProcessresponse to oleic acid

DGAT2 AACS

4.51e-0451402GO:0034201
GeneOntologyBiologicalProcesssodium ion transmembrane transport

TRPM2 SLC6A19 SLC13A3 SLC6A12 SLC6A13 NALCN SLC23A1

5.55e-042081407GO:0035725
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

GPM6A SLC26A3 TMC2 TRPM2 SLC6A19 SLC13A3 GRIK5 GRM6 TMC3 SLC40A1 SLC30A6 ITPR2 SLC6A12 SLC6A13 ATP11B NALCN HTR3B SLC23A1

5.56e-04111514018GO:0034220
GeneOntologyBiologicalProcesssodium ion transport

TRPM2 SLC6A19 SLC13A3 MFSD4B SLC6A12 SLC6A13 NALCN SLC23A1

5.91e-042751408GO:0006814
GeneOntologyCellularComponentastrocyte projection

ADGRG1 GRM2 GRM3 GRM5

2.25e-05251414GO:0097449
GeneOntologyCellularComponentsomatodendritic compartment

GPM6A STRN3 HTR6 MYO5B TRPM2 GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7 LRP8 GDPD5 EFNB2 CNTNAP4 MRGPRX3 HTR3B PLK3 EPHA10 CD200

2.21e-04122814120GO:0036477
GeneOntologyCellularComponentglial cell projection

ADGRG1 GRM2 GRM3 GRM5

2.82e-04471414GO:0097386
GeneOntologyCellularComponentpostsynaptic membrane

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7 PTPRT LRP8 EFNB2 HTR3B

4.33e-0440514110GO:0045211
GeneOntologyCellularComponentendoplasmic reticulum tubular network membrane

ATL1 ATL2

4.46e-0451412GO:0098826
GeneOntologyCellularComponentapical plasma membrane

SLC26A3 CYBRD1 SLC43A1 SLC6A19 SLC44A4 MFSD4B F2RL2 NOD1 PKHD1 SLC23A1 ABCG5

4.75e-0448714111GO:0016324
GeneOntologyCellularComponentbrush border

SLC26A3 CYBRD1 MYO5B SLC6A19 SLC23A1 MFSD10

5.86e-041521416GO:0005903
GeneOntologyCellularComponentsynaptic membrane

GPM6A GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7 PTPRT LRP8 EFNB2 CNTNAP4 HTR3B

6.02e-0458314112GO:0097060
GeneOntologyCellularComponentapical part of cell

SLC26A3 CYBRD1 MYO5B SLC43A1 SLC6A19 SLC44A4 MFSD4B F2RL2 NOD1 PKHD1 SLC23A1 ABCG5

6.88e-0459214112GO:0045177
GeneOntologyCellularComponentdendrite

GPM6A STRN3 HTR6 MYO5B GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7 LRP8 EFNB2 CNTNAP4 PLK3 EPHA10

6.96e-0485814115GO:0030425
GeneOntologyCellularComponentdendritic tree

GPM6A STRN3 HTR6 MYO5B GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7 LRP8 EFNB2 CNTNAP4 PLK3 EPHA10

7.13e-0486014115GO:0097447
GeneOntologyCellularComponentcleavage furrow

OR2A7 MYLK OR2A4 PLK4

7.68e-04611414GO:0032154
GeneOntologyCellularComponentcluster of actin-based cell projections

SLC26A3 CYBRD1 TMC2 MYO5B SLC6A19 SLC23A1 MFSD10

8.08e-042231417GO:0098862
GeneOntologyCellularComponentendoplasmic reticulum membrane

SLC37A3 OR7A5 SLC43A1 MARCHF6 AGPAT3 JKAMP GRM6 ATL1 TMEM33 ITPR2 GDPD5 G6PC3 DGAT2 CERS3 CYP2U1 OR2A25 HSD17B2 ATL2 FITM2

1.12e-03129314119GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

SLC37A3 OR7A5 SLC43A1 MARCHF6 AGPAT3 JKAMP GRM6 ATL1 TMEM33 ITPR2 GDPD5 G6PC3 DGAT2 CERS3 CYP2U1 OR2A25 HSD17B2 ATL2 FITM2

1.18e-03129914119GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

SLC37A3 OR7A5 SLC43A1 MARCHF6 AGPAT3 JKAMP GRM6 ATL1 TMEM33 ITPR2 GDPD5 G6PC3 DGAT2 CERS3 CYP2U1 OR2A25 HSD17B2 ATL2 FITM2

1.51e-03132714119GO:0042175
GeneOntologyCellularComponentreceptor complex

FLT1 TRA GRIK5 GPR101 GRM7 LRP8 ITPR2 HTR3B TRAV38-2DV8 ABCG5 PLXNB1

1.97e-0358114111GO:0043235
GeneOntologyCellularComponentcell division site

OR2A7 MYLK OR2A4 PLK4

2.11e-03801414GO:0032153
GeneOntologyCellularComponentbrush border membrane

SLC26A3 CYBRD1 SLC6A19 MFSD10

2.41e-03831414GO:0031526
GeneOntologyCellularComponentspindle midzone

OR2A7 OR2A4 PLK1

2.47e-03401413GO:0051233
GeneOntologyCellularComponentpresynaptic membrane

GPM6A GRIK5 GRM2 GRM3 GRM7 EFNB2 CNTNAP4

2.78e-032771417GO:0042734
GeneOntologyCellularComponentmitotic spindle pole

OR2A7 OR2A4 PLK1

3.04e-03431413GO:0097431
GeneOntologyCellularComponentpostsynapse

GPM6A STRN3 GPR50 MYO5B GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7 PTPRT LRP8 EFNB2 HTR3B CD200

3.69e-03101814115GO:0098794
DomainGPCR_Rhodpsn_7TM

OR2A14 OR8D1 OR2L8 OR2A7 OR2L3 GPR50 HTR6 OR7A5 OR9I1 OR2W1 GPR101 F2RL2 TAAR6 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 MRGPRX3 OR2A25 OR51V1 GPR176 OR9A2 OR2A2

1.28e-1067013824IPR017452
Domain7tm_1

OR2A14 OR8D1 OR2L8 OR2A7 OR2L3 GPR50 HTR6 OR7A5 OR9I1 OR2W1 GPR101 F2RL2 TAAR6 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 MRGPRX3 OR2A25 OR51V1 GPR176 OR9A2 OR2A2

1.59e-1067713824PF00001
DomainG_PROTEIN_RECEP_F1_1

OR2A14 OR8D1 OR2L8 OR2A7 OR2L3 GPR50 HTR6 OR7A5 OR9I1 OR2W1 GPR101 F2RL2 TAAR6 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 MRGPRX3 OR2A25 OR51V1 GPR176 OR9A2 OR2A2

2.01e-1068513824PS00237
DomainG_PROTEIN_RECEP_F1_2

OR2A14 OR8D1 OR2L8 OR2A7 OR2L3 GPR50 HTR6 OR7A5 OR9I1 OR2W1 GPR101 F2RL2 TAAR6 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 MRGPRX3 OR2A25 OR51V1 GPR176 OR9A2 OR2A2

2.40e-1069113824PS50262
DomainGPCR_Rhodpsn

OR2A14 OR8D1 OR2L8 OR2A7 OR2L3 GPR50 HTR6 OR7A5 OR9I1 OR2W1 GPR101 F2RL2 TAAR6 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 MRGPRX3 OR2A25 OR51V1 GPR176 OR9A2 OR2A2

2.47e-1069213824IPR000276
DomainGPCR_3_mtglu_rcpt

GRM2 GRM3 GRM5 GRM6 GRM7

1.13e-0981385IPR000162
DomainOlfact_rcpt

OR2A14 OR8D1 OR2L8 OR2A7 OR2L3 OR7A5 OR9I1 OR2W1 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 OR2A25 OR51V1 OR9A2 OR2A2

5.19e-0939313817IPR000725
DomainNCD3G

GRM2 GRM3 GRM5 GRM6 GRM7

2.51e-08131385PF07562
DomainGPCR_3_9-Cys_dom

GRM2 GRM3 GRM5 GRM6 GRM7

2.51e-08131385IPR011500
DomainGPCR_3_CS

GRM2 GRM3 GRM5 GRM6 GRM7

3.89e-08141385IPR017979
DomainANF_lig-bd_rcpt

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

2.81e-07371386IPR001828
DomainANF_receptor

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

2.81e-07371386PF01094
DomainGPCR_3

GRM2 GRM3 GRM5 GRM6 GRM7

3.79e-07211385IPR000337
DomainPeripla_BP_I

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

3.89e-07391386IPR028082
Domain7tm_3

GRM2 GRM3 GRM5 GRM6 GRM7

4.87e-07221385PF00003
DomainG_PROTEIN_RECEP_F3_2

GRM2 GRM3 GRM5 GRM6 GRM7

4.87e-07221385PS00980
DomainG_PROTEIN_RECEP_F3_3

GRM2 GRM3 GRM5 GRM6 GRM7

4.87e-07221385PS00981
DomainG_PROTEIN_RECEP_F3_1

GRM2 GRM3 GRM5 GRM6 GRM7

4.87e-07221385PS00979
DomainG_PROTEIN_RECEP_F3_4

GRM2 GRM3 GRM5 GRM6 GRM7

4.87e-07221385PS50259
DomainGPCR_3_C

GRM2 GRM3 GRM5 GRM6 GRM7

4.87e-07221385IPR017978
DomainPOLO_box

PLK1 PLK4 PLK3

1.57e-0641383PF00659
DomainPOLO_BOX

PLK1 PLK4 PLK3

1.57e-0641383PS50078
DomainPOLO_box_dom

PLK1 PLK4 PLK3

3.90e-0651383IPR000959
DomainRibosomal_S6_kinase_II

RPS6KA5 RPS6KA2 RPS6KA6

7.77e-0661383IPR016239
DomainPROTEIN_KINASE_ATP

FLT1 MYLK RPS6KA5 RPS6KA2 OBSCN MAPKAPK5 MKNK1 PIM3 RPS6KA6 PLK1 PLK4 PLK3 EPHA10

3.66e-0545913813PS00107
DomainTAS2R

TAS2R31 TAS2R43 TAS2R19 TAS2R46

3.76e-05261384PF05296
DomainT2R

TAS2R31 TAS2R43 TAS2R19 TAS2R46

3.76e-05261384IPR007960
DomainProt_kinase_dom

FLT1 MYLK RPS6KA5 RPS6KA2 OBSCN MAPKAPK5 MKNK1 PIM3 RPS6KA6 PLK1 PLK4 PLK3 EPHA10

6.97e-0548913813IPR000719
DomainS_TKc

MYLK RPS6KA5 RPS6KA2 OBSCN MAPKAPK5 MKNK1 PIM3 RPS6KA6 PLK1 PLK4 PLK3

7.41e-0535913811SM00220
DomainPROTEIN_KINASE_DOM

FLT1 MYLK RPS6KA5 RPS6KA2 OBSCN MAPKAPK5 MKNK1 PIM3 RPS6KA6 PLK1 PLK4 PLK3 EPHA10

7.57e-0549313813PS50011
DomainPROTEIN_KINASE_ST

MYLK RPS6KA5 RPS6KA2 OBSCN MAPKAPK5 MKNK1 PIM3 RPS6KA6 PLK1 PLK4 PLK3

7.98e-0536213811PS00108
DomainProtein_kinase_ATP_BS

FLT1 MYLK RPS6KA5 RPS6KA2 OBSCN MKNK1 PIM3 RPS6KA6 PLK1 PLK4 PLK3

1.20e-0437913811IPR017441
DomainPkinase

MYLK RPS6KA5 RPS6KA2 OBSCN MAPKAPK5 MKNK1 PIM3 RPS6KA6 PLK1 PLK4 PLK3

1.25e-0438113811PF00069
DomainCa/CaM-dep_Ca-dep_prot_Kinase

MAPKAPK5 MKNK1 PLK1 PLK4 PLK3

1.57e-04691385IPR020636
DomainPOLO_box_2

PLK1 PLK3

1.62e-0431382IPR033695
DomainKinase-like_dom

FLT1 MYLK RPS6KA5 RPS6KA2 OBSCN MAPKAPK5 MKNK1 PIM3 RPS6KA6 PLK1 PLK4 PLK3 EPHA10

1.94e-0454213813IPR011009
DomainMFS_1

SLC37A3 SLC43A1 MFSD4B MFSD1 MFSD10

2.64e-04771385PF07690
DomainMFS

SLC37A3 SLC43A1 MFSD4B MFSD1 MFSD10

2.64e-04771385IPR011701
Domain-

PLK1 PLK3

3.22e-04413823.30.1120.30
DomainGPR1/GPR3/GPR5

ADGRG3 ADGRG1

3.22e-0441382IPR003910
DomainPOLO_box_1

PLK1 PLK3

3.22e-0441382IPR033701
DomainSer/Thr_kinase_AS

MYLK RPS6KA5 RPS6KA2 OBSCN MAPKAPK5 MKNK1 PIM3 RPS6KA6 PLK1 PLK3

3.26e-0435713810IPR008271
DomainSNF

SLC6A19 SLC6A12 SLC6A13

3.51e-04191383PF00209
DomainNA_NEUROTRAN_SYMP_1

SLC6A19 SLC6A12 SLC6A13

3.51e-04191383PS00610
DomainNA_NEUROTRAN_SYMP_3

SLC6A19 SLC6A12 SLC6A13

3.51e-04191383PS50267
DomainNa/ntran_symport

SLC6A19 SLC6A12 SLC6A13

3.51e-04191383IPR000175
DomainMFS_dom

SLC37A3 SLC43A1 MFSD4B SLC40A1 MFSD1 MFSD10

4.83e-041341386IPR020846
DomainAMP-binding_CS

AACS ACSM2A ACSM2B

9.06e-04261383IPR020845
DomainAMP_BINDING

AACS ACSM2A ACSM2B

1.13e-03281383PS00455
DomainAMP-binding

AACS ACSM2A ACSM2B

1.38e-03301383PF00501
DomainAMP-dep_Synth/Lig

AACS ACSM2A ACSM2B

1.38e-03301383IPR000873
Domain7TM_GPCR_Srsx

OR8D1 GPR50 HTR6 TAAR6 OR51I1

1.46e-031121385SM01381
DomainTMC

TMC2 TMC3

1.47e-0381382PF07810
DomainTMC

TMC2 TMC3

1.47e-0381382IPR012496
DomainGPS

ADGRG3 ADGRG1 ADGRA2

2.00e-03341383SM00303
DomainGPS

ADGRG3 ADGRG1 ADGRA2

2.17e-03351383PF01825
DomainGBP_C

ATL1 ATL2

2.35e-03101382PF02841
DomainGPS

ADGRG3 ADGRG1 ADGRA2

2.36e-03361383PS50221
DomainGPS

ADGRG3 ADGRG1 ADGRA2

2.55e-03371383IPR000203
DomainPkinase_C

RPS6KA5 RPS6KA2 RPS6KA6

2.55e-03371383IPR017892
DomainG_GB1_RHD3_dom

ATL1 ATL2

2.85e-03111382IPR030386
DomainGuanylate-bd_C

ATL1 ATL2

2.85e-03111382IPR003191
DomainGBP

ATL1 ATL2

2.85e-03111382PF02263
DomainGuanylate-bd_N

ATL1 ATL2

2.85e-03111382IPR015894
DomainG_GB1_RHD3

ATL1 ATL2

2.85e-03111382PS51715
DomainPkinase_C

RPS6KA5 RPS6KA2 RPS6KA6

3.67e-03421383PF00433
DomainPROTEIN_KINASE_TYR

FLT1 OBSCN PLK4 EPHA10

5.82e-03971384PS00109
DomainTyr_kinase_AS

FLT1 OBSCN PLK4 EPHA10

5.82e-03971384IPR008266
DomainG_PROTEIN_RECEP_F2_2

ADGRG3 ADGRG1 ADGRA2

6.00e-03501383PS00650
Domain7tm_2

ADGRG3 ADGRG1 ADGRA2

6.00e-03501383PF00002
DomainMAM_1

PTPRT MEP1A

6.08e-03161382PS00740
DomainAMP-bd_C

ACSM2A ACSM2B

6.85e-03171382IPR025110
DomainAMP-binding_C

ACSM2A ACSM2B

6.85e-03171382PF13193
DomainMAM

PTPRT MEP1A

6.85e-03171382SM00137
PathwayREACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

GRM2 GRM3 GRM5 GRM6 GRM7 TAS2R31 TAS2R43 TAS2R19 TAS2R46

1.20e-11371159MM15067
PathwayREACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

GRM2 GRM3 GRM5 GRM6 GRM7 TAS2R31 TAS2R43 TAS2R19 TAS2R46

2.01e-11391159M793
PathwayWP_GPCRS_ODORANT

ADGRG3 OR2A7 OR7A5 GPR101 ADGRA2 TAAR6 GPR180 OR2A4 MRGPRX3 TAS2R31 TAS2R43 TAS2R19 TAS2R46 GPR176

3.40e-1115711514MM15872
PathwayREACTOME_SENSORY_PERCEPTION

OR2A14 OR8D1 OR2L8 OR2A7 TMC2 OR2L3 OR7A5 OR9I1 OR2W1 LRP8 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 OR1P1 OR2A25 TAS2R31 TAS2R43 TAS2R46 OR51V1 OR9A2 OR2A2

1.38e-0963611523M41834
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR2A14 OR8D1 OR2L8 OR2A7 OR2L3 OR7A5 OR9I1 OR2W1 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 OR1P1 OR2A25 OR51V1 OR9A2 OR2A2

7.12e-0941711518M4072
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR2A14 OR8D1 OR2L8 OR2A7 OR2L3 OR7A5 OR9I1 OR2W1 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 OR2A25 OR51V1 OR9A2 OR2A2

1.62e-0838911517M14091
PathwayWP_GPCRS_CLASS_C_METABOTROPIC_GLUTAMATE_PHEROMONE

GRM2 GRM3 GRM5 GRM6 GRM7

9.31e-08151155M39442
PathwayWP_GPCRS_CLASS_C_METABOTROPIC_GLUTAMATE_PHEROMONE

GRM2 GRM3 GRM5 GRM6 GRM7

9.31e-08151155MM15845
PathwayWP_GPCRS_OTHER

OR8D1 OR2A7 OR7A5 OR2W1 ADGRG1 OR2A4 OR1A1 OR1P1

1.12e-06961158MM15939
PathwayREACTOME_SIGNALING_BY_GPCR

HTR6 RPS6KA2 OBSCN GRM2 GRM3 GRM5 GRM6 GRM7 F2RL2 TAAR6 ITPR2 NPS TAS2R31 TAS2R43 TAS2R19 TAS2R46 GPR176 PLXNB1

4.63e-0664611518MM14962
PathwayREACTOME_SIGNALING_BY_GPCR

HTR6 RPS6KA2 OBSCN GRM2 GRM3 GRM5 GRM6 GRM7 F2RL2 TAAR6 ITPR2 NPS TAS2R31 TAS2R43 TAS2R19 TAS2R46 GPR176 PLXNB1

1.44e-0570211518M746
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC6A19 SLC13A3 SLC44A4 SLC40A1 SLC6A12 SLC6A13

3.55e-05761156MM15072
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC26A3 SLC43A1 SLC6A19 SLC13A3 SLC44A4 MFSD4B SLC40A1 SLC6A12 SLC6A13 LCN15

3.62e-0524911510M5988
PathwayREACTOME_GPCR_LIGAND_BINDING

HTR6 GRM2 GRM3 GRM5 GRM6 GRM7 F2RL2 TAAR6 NPS TAS2R31 TAS2R43 TAS2R19 TAS2R46

4.78e-0543011513MM15160
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC6A19 SLC13A3 SLC44A4 SLC40A1 SLC6A12 SLC6A13

6.26e-05841156M27334
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

GPR50 HTR6 GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7 F2RL2 TAAR6

7.61e-0527211510M13380
PathwayREACTOME_GPCR_LIGAND_BINDING

HTR6 GRM2 GRM3 GRM5 GRM6 GRM7 F2RL2 TAAR6 NPS TAS2R31 TAS2R43 TAS2R19 TAS2R46

1.01e-0446311513M507
PathwayREACTOME_SENSORY_PERCEPTION_OF_TASTE

TAS2R31 TAS2R43 TAS2R19 TAS2R46

1.12e-04311154MM15691
PathwayREACTOME_SENSORY_PERCEPTION

OR8D1 OR2W1 LRP8 OR1A1 TAS2R31 TAS2R43 TAS2R19 TAS2R46

1.63e-041901158MM15687
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC26A3 CYBRD1 MYO5B SLC43A1 TRPM2 SLC6A19 SLC13A3 SLC44A4 MFSD4B SLC40A1 SLC6A12 SLC6A13 ATP11B NALCN LCN15 ABCG5

3.07e-0473611516M27287
PathwayWP_GPCRS_NONODORANT

GPR50 HTR6 ADGRG1 GRM2 GRM3 GRM5 GRM6 GRM7 F2RL2

3.26e-042661159MM15843
PathwayREACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS

SLC6A19 SLC6A12 SLC6A13

4.66e-04191153M27362
PathwayREACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS

SLC6A19 SLC6A12 SLC6A13

4.66e-04191153MM15107
PathwayREACTOME_CREB1_PHOSPHORYLATION_THROUGH_NMDA_RECEPTOR_MEDIATED_ACTIVATION_OF_RAS_SIGNALING

RPS6KA2 RPS6KA6

6.49e-0451152MM15108
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC26A3 SLC43A1 SLC6A19 SLC13A3 SLC44A4 SLC40A1 SLC6A12 SLC6A13

7.35e-042381158MM15076
PathwayKEGG_TASTE_TRANSDUCTION

TAS2R31 TAS2R43 TAS2R19 TAS2R46

8.41e-04521154M5785
PathwayREACTOME_CONJUGATION_OF_SALICYLATE_WITH_GLYCINE

ACSM2A ACSM2B

9.69e-0461152MM14693
PathwayKEGG_MEDICUS_REFERENCE_ERK_RSK_SIGNALING

RPS6KA2 RPS6KA6

9.69e-0461152M47936
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

GRM2 GRM3 GRM6 GRM7 ITPR2 TAS2R31 TAS2R43 TAS2R19 TAS2R46

1.07e-033141159M600
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC26A3 CYBRD1 MYO5B SLC43A1 TRPM2 SLC6A19 SLC13A3 SLC44A4 SLC40A1 SLC6A12 SLC6A13 ATP11B NALCN ABCG5

1.28e-0368111514MM14985
PathwayREACTOME_RSK_ACTIVATION

RPS6KA2 RPS6KA6

1.35e-0371152M27369
PathwayREACTOME_AMINO_ACID_CONJUGATION

ACSM2A ACSM2B

1.35e-0371152MM14598
PathwayREACTOME_CREB_PHOSPHORYLATION

RPS6KA5 RPS6KA2

1.35e-0371152M27096
PathwayREACTOME_CREB_PHOSPHORYLATION

RPS6KA5 RPS6KA2

1.35e-0371152MM14784
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR2A14 OR8D1 OR2L8 OR2A7 OR2L3 OR7A5 OR9I1 OR2W1 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 OR1P1 OR2A25 OR51V1 OR9A2 OR2A2

4.49e-153401431811875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR2A14 OR8D1 OR2L8 OR2A7 OR2L3 OR7A5 OR9I1 OR2W1 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 OR1P1 OR2A25 OR51V1 OR9A2 OR2A2

4.49e-153401431811802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR2A14 OR8D1 OR2L8 OR2A7 OR2L3 OR7A5 OR9I1 OR2W1 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 OR1P1 OR2A25 OR51V1 OR9A2 OR2A2

5.23e-153431431832295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR2A14 OR8D1 OR2L8 OR2A7 OR2L3 OR7A5 OR9I1 OR2W1 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 OR1P1 OR2A25 OR51V1 OR9A2 OR2A2

6.07e-153461431814611657
Pubmed

Metabotropic glutamate receptor subtype 7 ablation causes deficit in fear response and conditioned taste aversion.

GRM2 GRM3 GRM5 GRM6 GRM7

2.28e-11714359920659
Pubmed

Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors.

GRM2 GRM3 GRM5 GRM6 GRM7

2.71e-101014359069281
Pubmed

Glutamate can act as a signaling molecule in mouse preimplantation embryos†.

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

5.50e-1024143635746896
Pubmed

The human olfactory receptor gene family.

OR2A14 OR8D1 OR2L8 OR2A7 OR7A5 OR9I1 OR2W1 OR2A12 OR51I1 OR2A4 OR1A1 OR2D3 OR1P1 OR51V1 OR9A2 OR2A2

9.38e-105411431614983052
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR2A14 OR2A7 OR7A5 OR9I1 OR2W1 OR2A12 OR1A1 OR2D3 OR1P1 OR2A2

2.75e-082191431012213199
Pubmed

The G protein-coupled receptor repertoires of human and mouse.

ADGRG3 GPR101 GRM2 GRM5 GRM6 GRM7 GPR176

3.88e-0879143712679517
Pubmed

Metabotropic glutamate receptor mGluR2/3 and mGluR5 binding in the anterior cingulate cortex in psychotic and nonpsychotic depression, bipolar disorder and schizophrenia: implications for novel mGluR-based therapeutics.

GRM2 GRM3 GRM5

6.81e-083143324949866
Pubmed

The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides.

TAS2R31 TAS2R43 TAS2R19 TAS2R46

1.32e-0712143412379855
Pubmed

Mapping of QTLs for oral alcohol self-administration in B6.C and B6.I quasi-congenic RQI strains.

GRM7 TAS2R31 TAS2R43 TAS2R19 TAS2R46

1.44e-0730143517273929
Pubmed

Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice.

TAS2R31 TAS2R43 TAS2R19 TAS2R46

1.90e-0713143415938754
Pubmed

Evolution of odorant receptors expressed in mammalian testes.

OR8D1 OR2A7 OR7A5 OR2A4

1.90e-0713143411014824
Pubmed

Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system.

GRM2 GRM3 GRM5

2.71e-074143329079293
Pubmed

Identification and assessment of PLK1/2/3/4 in lung adenocarcinoma and lung squamous cell carcinoma: Evidence from methylation profile.

PLK1 PLK4 PLK3

2.71e-074143334080290
Pubmed

Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.

HTR6 GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7 SLC6A12 SLC6A13 HTR3B

5.11e-073001431019086053
Pubmed

Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.

HTR6 GRM2 GRM3 GRM5 GRM6 GRM7 HTR3B

6.18e-07118143719156168
Pubmed

Dual metabotropic glutamate receptor signaling enables coordination of astrocyte and neuron activity in developing sensory domains.

GRM3 GRM5 ITPR2

6.77e-075143334245686
Pubmed

Serine 727 phosphorylation and activation of cytosolic phospholipase A2 by MNK1-related protein kinases.

RPS6KA5 MAPKAPK5 MKNK1

6.77e-075143310978317
Pubmed

Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord.

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

1.10e-0681143622723691
Pubmed

Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.

GRM2 GRM3 GRM5 GRM6 GRM7

1.17e-0645143525979088
Pubmed

A novel family of mammalian taste receptors.

TAS2R31 TAS2R43 TAS2R19 TAS2R46

1.55e-0621143410761934
Pubmed

Evolutionary relationships of the Tas2r receptor gene families in mouse and human.

TAS2R31 TAS2R43 TAS2R19 TAS2R46

1.89e-0622143412734386
Pubmed

The molecular receptive ranges of human TAS2R bitter taste receptors.

TAS2R31 TAS2R43 TAS2R19 TAS2R46

2.28e-0623143420022913
Pubmed

Receptors for bitter and sweet taste.

TAS2R31 TAS2R43 TAS2R19 TAS2R46

3.24e-0625143412139982
Pubmed

Tamalin, a PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins.

GRM2 GRM3 GRM5

3.75e-068143311850456
Pubmed

Molecular mechanisms of bitter and sweet taste transduction.

TAS2R31 TAS2R43 TAS2R19 TAS2R46

3.82e-0626143411696554
Pubmed

Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.

TAS2R31 TAS2R43 TAS2R19 TAS2R46

4.47e-0627143412581520
Pubmed

Adaptive diversification of bitter taste receptor genes in Mammalian evolution.

TAS2R31 TAS2R43 TAS2R19 TAS2R46

6.91e-0630143412679530
Pubmed

Evolution of bitter taste receptors in humans and apes.

TAS2R31 TAS2R43 TAS2R19 TAS2R46

1.15e-0534143415496549
Pubmed

Identification of ligands for olfactory receptors by functional expression of a receptor library.

OR2W1 OR1A1 OR1P1

1.46e-051214339875846
Pubmed

The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs.

GRM2 GRM3 GRM7

1.46e-0512143311891216
Pubmed

Selective silencing of individual dendritic branches by an mGlu2-activated potassium conductance in dentate gyrus granule cells.

GRM2 GRM3

1.68e-052143223616537
Pubmed

Group II metabotropic glutamate receptor blockade promotes stress resilience in mice.

GRM2 GRM3

1.68e-052143230939596
Pubmed

The use of knock-out mice unravels distinct roles for mGlu2 and mGlu3 metabotropic glutamate receptors in mechanisms of neurodegeneration/neuroprotection.

GRM2 GRM3

1.68e-052143217670976
Pubmed

The effect of mGlu2/3 receptors on synaptic activities to different types of GABAergic interneurons in the anterior cingulate cortex.

GRM2 GRM3

1.68e-052143232525061
Pubmed

Expression and subcellular distribution of glutamate receptor subunits 2/3 in the developing cerebellar cortex.

GRM2 GRM3

1.68e-05214328838577
Pubmed

Metabotropic Glutamate Receptor 2/3 Activation Improves Motor Performance and Reduces Pathology in Heterozygous zQ175 Huntington Disease Mice.

GRM2 GRM3

1.68e-052143234330748
Pubmed

Activation of mGlu3 metabotropic glutamate receptors enhances GDNF and GLT-1 formation in the spinal cord and rescues motor neurons in the SOD-1 mouse model of amyotrophic lateral sclerosis.

GRM2 GRM3

1.68e-052143225434487
Pubmed

Unexpected redundancy of Gpr56 and Gpr97 during hematopoietic cell development and differentiation.

ADGRG3 ADGRG1

1.68e-052143233560396
Pubmed

NAAG Peptidase Inhibitors Act via mGluR3: Animal Models of Memory, Alzheimer's, and Ethanol Intoxication.

GRM2 GRM3

1.68e-052143228285415
Pubmed

mGlu2/3 receptor in the prelimbic cortex is implicated in stress resilience and vulnerability in mice.

GRM2 GRM3

1.68e-052143234090896
Pubmed

Pharmacological activation of group-II metabotropic glutamate receptors corrects a schizophrenia-like phenotype induced by prenatal stress in mice.

GRM2 GRM3

1.68e-052143222089319
Pubmed

Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines.

ACSM2A ACSM2B

1.68e-052143219634011
Pubmed

Bitter taste receptors for saccharin and acesulfame K.

TAS2R31 TAS2R43

1.68e-052143215537898
Pubmed

Regulation of cocaine-induced reinstatement by group II metabotropic glutamate receptors in the ventral tegmental area.

GRM2 GRM3

1.68e-052143221881873
Pubmed

Polo box domain of Plk3 functions as a centrosome localization signal, overexpression of which causes mitotic arrest, cytokinesis defects, and apoptosis.

PLK1 PLK3

1.68e-052143216478733
Pubmed

Fractionation of spatial memory in GRM2/3 (mGlu2/mGlu3) double knockout mice reveals a role for group II metabotropic glutamate receptors at the interface between arousal and cognition.

GRM2 GRM3

1.68e-052143221832989
Pubmed

The role of group II metabotropic glutamate receptors in cognition and anxiety: comparative studies in GRM2(-/-), GRM3(-/-) and GRM2/3(-/-) knockout mice.

GRM2 GRM3

1.68e-052143225158312
Pubmed

Altered hippocampal expression of glutamate receptors and transporters in GRM2 and GRM3 knockout mice.

GRM2 GRM3

1.68e-052143218720515
Pubmed

The C terminus of the metabotropic glutamate receptor subtypes 2 and 7 specifies the receptor signaling pathways.

GRM2 GRM7

1.68e-052143211584003
Pubmed

Metabotropic glutamate receptor 2/3 in the hippocampus of patients with mesial temporal lobe epilepsy, and of rats and mice after pilocarpine-induced status epilepticus.

GRM2 GRM3

1.68e-052143215246118
Pubmed

The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase.

PLK1 PLK3

1.68e-052143211931760
Pubmed

Metabotropic glutamate receptor 2 and 3 gene expression in the human prefrontal cortex and mesencephalon in schizophrenia.

GRM2 GRM3

1.68e-052143218853337
Pubmed

Hippocampal mossy fiber long-term depression in Grm2/3 double knockout mice.

GRM2 GRM3

1.68e-052143221360593
Pubmed

Developmental expression of mGlu2 and mGlu3 in the mouse brain.

GRM2 GRM3

1.68e-052143227818290
Pubmed

Activation of metabotropic glutamate receptor type 2/3 supports the involvement of the hippocampal mossy fiber pathway on contextual fear memory consolidation.

GRM2 GRM3

1.68e-052143219638469
Pubmed

Enhancement of CA3 hippocampal network activity by activation of group II metabotropic glutamate receptors.

GRM2 GRM3

1.68e-052143221628565
Pubmed

The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.

ACSM2A ACSM2B

1.68e-052143216521160
Pubmed

Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin.

TAS2R31 TAS2R43

1.68e-052143217702579
Pubmed

RSK3/4 mediate resistance to PI3K pathway inhibitors in breast cancer.

RPS6KA2 RPS6KA6

1.68e-052143223635776
Pubmed

TRPM2, linking oxidative stress and Ca2+ permeation to NLRP3 inflammasome activation.

TRPM2 NLRP3

1.68e-052143232058297
Pubmed

Decreased striatal dopamine in group II metabotropic glutamate receptor (mGlu2/mGlu3) double knockout mice.

GRM2 GRM3

1.68e-052143224053122
Pubmed

Adaptive Changes in Group 2 Metabotropic Glutamate Receptors Underlie the Deficit in Recognition Memory Induced by Methamphetamine in Mice.

GRM2 GRM3

1.68e-052143238969501
Pubmed

Activating mGlu3 Metabotropic Glutamate Receptors Rescues Schizophrenia-like Cognitive Deficits Through Metaplastic Adaptations Within the Hippocampus.

GRM3 GRM5

1.68e-052143233965197
Pubmed

Oxidative stress promotes ventilator-induced lung injury through activating NLRP3 inflammasome and TRPM2 channel.

TRPM2 NLRP3

1.68e-052143231411068
Pubmed

Metabotropic glutamate receptor 3 activation is required for long-term depression in medial prefrontal cortex and fear extinction.

GRM2 GRM3

1.68e-052143225583490
Pubmed

The mGluR2/3 agonist LY379268 induced anti-reinstatement effects in rats exhibiting addiction-like behavior.

GRM2 GRM3

1.68e-052143223624743
Pubmed

Deletion of Metabotropic Glutamate Receptors 2 and 3 (mGlu2 & mGlu3) in Mice Disrupts Sleep and Wheel-Running Activity, and Increases the Sensitivity of the Circadian System to Light.

GRM2 GRM3

1.68e-052143225950516
Pubmed

Association analysis of group II metabotropic glutamate receptor genes (GRM2 and GRM3) with mood disorders and fluvoxamine response in a Japanese population.

GRM2 GRM3

1.68e-052143219386277
Pubmed

The metabotropic glutamate receptor types 2/3 inhibit L-type calcium channels via a pertussis toxin-sensitive G-protein in cultured cerebellar granule cells.

GRM2 GRM3

1.68e-05214327965099
Pubmed

Glutamate receptors and the regulation of steroidogenesis in the human adrenal gland: the metabotropic pathway.

GRM2 GRM3

1.68e-052143224080311
Pubmed

Reconstitution of human atlastin fusion activity reveals autoinhibition by the C terminus.

ATL1 ATL2

1.68e-052143234817557
Pubmed

TRPM2 links oxidative stress to NLRP3 inflammasome activation.

TRPM2 NLRP3

1.68e-052143223511475
Pubmed

Structures of human mGlu2 and mGlu7 homo- and heterodimers.

GRM2 GRM7

1.68e-052143234135509
Pubmed

Analyses of the genetic diversity and protein expression variation of the acyl: CoA medium-chain ligases, ACSM2A and ACSM2B.

ACSM2A ACSM2B

1.68e-052143229948332
Pubmed

Metabotropic glutamate receptors are expressed in adult human glial progenitor cells.

GRM3 GRM5

1.68e-052143215158450
Pubmed

Activation of Group II Metabotropic Glutamate Receptors Promotes LTP Induction at Schaffer Collateral-CA1 Pyramidal Cell Synapses by Priming NMDA Receptors.

GRM2 GRM3

1.68e-052143227911756
Pubmed

Reduction of group II metabotropic glutamate receptors during development of benzodiazepine dependence.

GRM2 GRM3

1.68e-052143223392308
Pubmed

Increased binding of cortical and hippocampal group II metabotropic glutamate receptors in isolation-reared mice.

GRM2 GRM3

1.68e-052143220970439
Pubmed

Glutamate-dependent neuroglial calcium signaling differs between young and adult brain.

GRM3 GRM5

1.68e-052143223307741
Pubmed

Expression and functional role of mGluR3 and mGluR5 in human astrocytes and glioma cells: opposite regulation of glutamate transporter proteins.

GRM3 GRM5

1.68e-052143212786977
Pubmed

Non-mitotic functions of polo-like kinases in cancer cells.

PLK1 PLK4

1.68e-052143233171265
Pubmed

Behavioural and biochemical responses to methamphetamine are differentially regulated by mGlu2 and mGlu3 metabotropic glutamate receptors in male mice.

GRM2 GRM3

1.68e-052143234217776
Pubmed

Roles of metabotropic glutamate receptors in glial function and glial-neuronal communication.

GRM3 GRM5

1.68e-05214328915890
Pubmed

Memantine-induced brain activation as a model for the rapid screening of potential novel antipsychotic compounds: exemplified by activity of an mGlu2/3 receptor agonist.

GRM2 GRM3

1.68e-052143221057775
Pubmed

Identification and characterization of human taste receptor genes belonging to the TAS2R family.

TAS2R31 TAS2R43 TAS2R46

1.89e-0513143312584440
Pubmed

Polo-like kinase is required for synaptonemal complex disassembly and phosphorylation in mouse spermatocytes.

PLK1 PLK4 PLK3

1.89e-0513143322854038
Pubmed

The deregulated promoter methylation of the Polo-like kinases as a potential biomarker in hematological malignancies.

PLK1 PLK4

5.02e-053143225347426
Pubmed

Graded heterogeneity of metabotropic signaling underlies a continuum of cell-intrinsic temporal responses in unipolar brush cells.

GRM2 GRM3

5.02e-053143234620856
Pubmed

Knockdown of TRPM2 promotes osteogenic differentiation of human periodontal ligament stem cells by modulating NF-κB /NLRP3 pathway.

TRPM2 NLRP3

5.02e-053143237541115
Pubmed

Human atlastin GTPases mediate differentiated fusion of endoplasmic reticulum membranes.

ATL1 ATL2

5.02e-053143225773277
Pubmed

Expression of iron absorption genes in mouse large intestine.

CYBRD1 SLC40A1

5.02e-053143215764147
Pubmed

Clinical significance of glutamate metabotropic receptors in renal cell carcinoma risk and survival.

GRM3 GRM5

5.02e-053143230488581
Pubmed

Astrocytic γ-aminobutyric acid (GABA) transporters mediate guanidinoacetate transport in rat brain.

SLC6A12 SLC6A13

5.02e-053143229175673
Pubmed

Two olfactory receptors-OR2A4/7 and OR51B5-differentially affect epidermal proliferation and differentiation.

OR2A7 OR2A4

5.02e-053143227315375
Pubmed

Astrocytic PAR1 and mGluR2/3 control synaptic glutamate time course at hippocampal CA1 synapses.

GRM2 GRM3

5.02e-053143238864289
Pubmed

GRIP1 Binds to ApoER2 and EphrinB2 to Induce Activity-Dependent AMPA Receptor Insertion at the Synapse.

LRP8 EFNB2

5.02e-053143228978486
Cytoband7q35

OR2A14 OR2A7 OR2A12 OR2A25 OR2A2

8.39e-075514357q35
CytobandEnsembl 112 genes in cytogenetic band chr7q35

OR2A14 OR2A7 OR2A12 OR2A25 OR2A2

2.10e-06661435chr7q35
Cytoband12p13.2

TAS2R31 TAS2R43 TAS2R19 TAS2R46

1.22e-0545143412p13.2
CytobandEnsembl 112 genes in cytogenetic band chr12p13

SLC6A12 SLC6A13 TAS2R31 TAS2R43 TAS2R19 TAS2R46

8.75e-043531436chr12p13
Cytoband4q21.21

RASGEF1B PAQR3

9.85e-041514324q21.21
Cytoband2p22.3

SLC30A6 ATL2

1.59e-031914322p22.3
Cytoband7q31

SLC26A3 SND1-IT1

3.21e-032714327q31
GeneFamilyGlutamate metabotropic receptors|Protein phosphatase 1 regulatory subunits

GRM2 GRM3 GRM5 GRM6 GRM7

4.81e-1081135281
GeneFamilyOlfactory receptors, family 2

OR2A14 OR2L8 OR2A7 OR2L3 OR2W1 OR2A12 OR2A4 OR2D3 OR2A25 OR2A2

2.20e-0911311310149
GeneFamilyMitogen-activated protein kinase-activated protein kinases

RPS6KA5 RPS6KA2 MAPKAPK5 MKNK1 RPS6KA6

3.91e-091111351156
GeneFamilySolute carriers

SLC26A3 SLC37A3 SLC43A1 SLC6A19 SLC13A3 SLC44A4 SLC40A1 SLC30A6 SLC6A12 SLC6A13 SLC23A1

3.73e-0539511311752
GeneFamilyTaste 2 receptors

TAS2R31 TAS2R43 TAS2R19 TAS2R46

1.01e-043911341162
GeneFamilyAcyl-CoA synthetase family

AACS ACSM2A ACSM2B

5.57e-0426113340
GeneFamilyAdhesion G protein-coupled receptors, subfamily G

ADGRG3 ADGRG1

7.97e-0471132917
GeneFamilyTransmembrane channel likes

TMC2 TMC3

1.06e-03811321135
GeneFamilyG protein-coupled receptors, Class A orphans

GPR50 GPR101 MRGPRX3 GPR176

1.45e-03781134262
GeneFamilyUPF1 like RNA helicases

SETX DNA2

2.05e-031111321169
GeneFamilyWD repeat domain containing

STRN3 AHI1 WDR27 PRPF4 NBEAL2 WDR24

6.08e-032621136362
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_top-relative-expression-ranked_200

GPM6A SLC13A3 SLC44A4 MEP1A SLC6A13 PKHD1 HSD17B2 ACSM2A SLC23A1

1.96e-071511209gudmap_developingKidney_e15.5_early proxim tubul_200
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_top-relative-expression-ranked_1000

AHI1 MYO5B MROH2A SLC6A19 SLC13A3 SLC44A4 MFSD4B SLC30A6 MEP1A SLC6A13 PAPOLA DGAT2 NBEAL2 PKHD1 ATL2 TMEM19 ACSM2A SLC23A1

2.60e-0775812018gudmap_developingKidney_e15.5_Proximal Tubules_1000
CoexpressionAtlaskidney single cell_adult_RenalCortexMixed_StemCellamp_k-means-cluster#4_top-relative-expression-ranked_500

GPM6A SLC6A19 AGPAT3 SLC13A3 SLC44A4 MEP1A SLC6A13 DGAT2 TMEM19 ACSM2A MFSD1 SLC23A1

2.39e-0639312012gudmap_kidney single cell_adult_RenalCortexMixed_Scamp_k4_500
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#4_top-relative-expression-ranked_1000

SLC13A3 SLC44A4 MFSD4B MEP1A SLC6A13 DGAT2 PKHD1 TMEM19 ACSM2A

2.75e-062071209gudmap_developingKidney_e15.5_Proximal Tubules_1000_k4
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_top-relative-expression-ranked_500

GPM6A SLC13A3 SLC44A4 MFSD4B MEP1A SLC6A13 DGAT2 PKHD1 HSD17B2 ACSM2A SLC23A1

1.45e-0539312011gudmap_developingKidney_e15.5_early proxim tubul_500
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#1_top-relative-expression-ranked_500

SLC13A3 MFSD4B MEP1A SLC6A13 PKHD1 ACSM2A

1.98e-05981206gudmap_developingKidney_e15.5_Proximal Tubules_500_k1
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_top-relative-expression-ranked_200

SLC13A3 SLC44A4 MEP1A SLC6A13 PKHD1 ACSM2A SLC23A1

2.23e-051491207gudmap_developingKidney_e15.5_Proximal Tubules_200
CoexpressionAtlaskidney single cell_adult_RenalCortexMixed_StemCellamp_k-means-cluster#3_top-relative-expression-ranked_200

SLC6A19 AGPAT3 MEP1A SLC6A13 DGAT2 ACSM2A SLC23A1

2.33e-051501207gudmap_kidney single cell_adult_RenalCortexMixed_Scamp_k3_200
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_k-means-cluster#5_top-relative-expression-ranked_500

SLC13A3 SLC44A4 MFSD4B MEP1A DGAT2 ACSM2A

2.78e-051041206gudmap_developingKidney_e15.5_early proxim tubul_500_k5
CoexpressionAtlaskidney_adult_RenalCortexMixed_Std_top-relative-expression-ranked_500

GPM6A SLC6A19 SLC13A3 SLC44A4 MEP1A SLC6A13 PKHD1 HSD17B2 TMEM19 ACSM2A SLC23A1

2.92e-0542412011gudmap_kidney_adult_RenalCortexMixed_Std_500
CoexpressionAtlaskidney single cell_adult_RenalCortexMixed_StemCellamp_top-relative-expression-ranked_200

SLC6A19 AGPAT3 MEP1A SLC6A13 DGAT2 ACSM2A SLC23A1

4.13e-051641207gudmap_kidney single cell_adult_RenalCortexMixed_Scamp_200
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_k-means-cluster#5_top-relative-expression-ranked_1000

SLC13A3 SLC44A4 MFSD4B MEP1A SLC6A13 DGAT2 TMEM19 ACSM2A

4.98e-052301208gudmap_developingKidney_e15.5_early proxim tubul_1000_k5
CoexpressionAtlaskidney single cell_adult_RenalCortexMixed_StemCellamp_k-means-cluster#1_top-relative-expression-ranked_1000

GPM6A SLC6A19 AGPAT3 SLC13A3 SLC44A4 MAPKAPK5 MEP1A SLC6A13 DGAT2 AACS HSD17B2 TMEM19 ACSM2A MFSD1 SLC23A1

7.03e-0583112015gudmap_kidney single cell_adult_RenalCortexMixed_Scamp_k1_1000
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_top-relative-expression-ranked_500

MYO5B MROH2A SLC13A3 SLC44A4 MFSD4B MEP1A SLC6A13 PKHD1 ACSM2A SLC23A1

7.36e-0538912010gudmap_developingKidney_e15.5_Proximal Tubules_500
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#5_top-relative-expression-ranked_200

SLC13A3 MEP1A PKHD1 ACSM2A

9.20e-05421204gudmap_developingKidney_e15.5_Proximal Tubules_200_k5
CoexpressionAtlaskidney

CLDN14 SLC6A19 SLC13A3 SLC6A12 SLC6A13 PKHD1 ACSM2A SLC23A1 ACSM2B

9.30e-053231209kidney
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_top-relative-expression-ranked_1000

GPM6A MYO5B SLC13A3 SLC44A4 MFSD4B MEP1A SLC6A13 DGAT2 NBEAL2 PKHD1 HSD17B2 TMEM19 ACSM2A SLC23A1

1.39e-0478412014gudmap_developingKidney_e15.5_early proxim tubul_1000
CoexpressionAtlasDevelopingKidney_e15.5_Medullary collecting duct_emap-28063_top-relative-expression-ranked_1000

STRN3 ADGRG3 AHI1 MYO5B SLC44A4 SLC40A1 ITPR2 DGAT2 NBEAL2 CERS3 PKHD1 ATL2 ACSM2A PLXNB1

1.43e-0478612014gudmap_developingKidney_e15.5_Medullary collecting duct_1000
CoexpressionAtlaskidney single cell_adult_RenalCortexMixed_StemCellamp_top-relative-expression-ranked_1000

GPM6A SLC6A19 AGPAT3 SLC13A3 SLC44A4 MAPKAPK5 MEP1A SLC6A13 DGAT2 AACS HSD17B2 TMEM19 ACSM2A MFSD1 SLC23A1

1.45e-0488712015gudmap_kidney single cell_adult_RenalCortexMixed_Scamp_1000
CoexpressionAtlasgudmap_RNAseq_p2_Glomerlular Endothelial_2500_K2

FLT1 ADGRG1 PIM3 NOD1 EFNB2 NBEAL2 PLK3 CD200

1.52e-042701208gudmap_RNAseq_p2_Glomerlular Endothelial_2500_K2
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_top-relative-expression-ranked_1000

GPM6A SLC6A19 AGPAT3 ADGRG1 SLC13A3 SLC44A4 ITPR2 MEP1A SLC6A13 DGAT2 PKHD1 ACSM2A MFSD1 SLC23A1

1.70e-0479912014gudmap_kidney_adult_JuxtaGlom_Ren1_1000
CoexpressionAtlasDevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#2_top-relative-expression-ranked_1000

MYO5B SLC44A4 DGAT2 PKHD1 ACSM2A

2.15e-04961205gudmap_developingKidney_e15.5_Medullary collecting duct_1000_k2
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#2_top-relative-expression-ranked_200

SLC44A4 SLC6A13 ACSM2A

2.87e-04231203gudmap_developingKidney_e15.5_Proximal Tubules_200_k2
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_k-means-cluster#4_top-relative-expression-ranked_1000

GPM6A AGPAT3 SLC44A4 MEP1A SLC6A13 DGAT2 MFSD1 SLC23A1

3.38e-043041208gudmap_kidney_adult_JuxtaGlom_Ren1_k4_1000
CoexpressionAtlaskidney_adult_RenalCortexMixed_Std_top-relative-expression-ranked_1000

GPM6A SLC6A19 AGPAT3 SLC13A3 SLC44A4 MEP1A SLC6A13 DGAT2 PKHD1 HSD17B2 TMEM19 ACSM2A MFSD1 SLC23A1

3.63e-0486112014gudmap_kidney_adult_RenalCortexMixed_Std_1000
CoexpressionAtlasMyeloid Cells, DC.103+11b-.Lu, MHCII+ CD11c+ CD103+ CD11b, Lung, avg-2

NAALAD2 RPS6KA2 F2RL2 NLRP3 ADGB ZDHHC23 DGAT2 RASGEF1B DNA2

4.70e-044021209GSM854241_500
CoexpressionAtlasduodenum

SLC26A3 SLC6A19 SLC44A4 MEP1A LCN15 HSD17B2 SLC23A1 ABCG5

4.85e-043211208duodenum
CoexpressionAtlasDevelopingLowerUrinaryTract_e15.5_Urothelium_emap-28091_top-relative-expression-ranked_1000

MYO5B SLC40A1 MEP1A EFNB2 DGAT2 PCNX4 NBEAL2 CERS3 PKHD1 HSD17B2 ATL2 ACSM2A PLXNB1

4.95e-0478412013gudmap_developingLowerUrinaryTract_e15.5_urothelium_1000
CoexpressionAtlasStem Cells, SC.GMP.BM, Lineage- sca1- ckithi CD34+ FcgRhi, Bone marrow, avg-3

ADGRG3 RPS6KA2 SLC43A1 ADGRG1 SLC40A1 G6PC3 PLK1 CMTM7 MFSD10

5.05e-044061209GSM791119_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500_k-means-cluster#3

GPM6A GPR50 ADGRG1 PLK3 PLXNB1

5.58e-041181205Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500_K3
ToppCellfacs-Heart-RA-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A FLT1 ADGRG3 RPS6KA2 ADGRA2 ITPR2 RASGEF1B ATL2

1.76e-0718814384ddb11a90bf3baa7237bde304db44dfcc56aed52
ToppCellfacs-Heart-RA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A FLT1 ADGRG3 RPS6KA2 ADGRA2 ITPR2 RASGEF1B ATL2

1.76e-071881438e47e66906922d5c69b1aafe28face0787d3fc563
ToppCellfacs-Kidney|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 SLC6A19 SLC13A3 MEP1A SLC6A13 SLC23A1 ACSM2B

1.22e-061681437d2f17a470e04f8f0edb111894027bcfc6ee1a12f
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Enterocyte|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A3 MYO5B SLC44A4 MEP1A EFNB2 DGAT2 HSD17B2

1.54e-0617414372fbdb62e269acf4447b171700a615e878dde7f9f
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A3 MYO5B SLC44A4 MEP1A EFNB2 DGAT2 HSD17B2

1.54e-0617414377c52b5d8f1e65e5208c952be341fa155ed0e6e76
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A3 MYLK MYO5B MEP1A EFNB2 DGAT2 HSD17B2

1.66e-0617614377622f5a8e7320cc7b593141854107ecaf4adff7f
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

CLDN14 SLC13A3 RASGEF1B PKHD1 OR2D3 ACSM2A ACSM2B

1.66e-06176143736f77d878a53b30465b0dea8333a3865dba75613
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GPM6A SLC13A3 SLC6A12 SLC6A13 PKHD1 ACSM2A ACSM2B

1.73e-0617714372f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

GPM6A SLC26A3 SLC6A19 GRM7 PTPRT RASGEF1B ACSM2A

2.00e-061811437c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A19 SLC13A3 MEP1A SLC6A13 DGAT2 SLC23A1 ACSM2B

2.08e-061821437faf0dfa3adc2d2706b6942b5127093ccdc856447
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A19 SLC13A3 MEP1A SLC6A13 DGAT2 SLC23A1 ACSM2B

2.08e-061821437be8dd52898525ce6632af0adc2801944f3ac10bd
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

GPM6A SLC13A3 SLC44A4 SLC6A13 PKHD1 ACSM2A ACSM2B

2.23e-06184143751ed1ebfdef45149541917c66cbacad87072e51f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO5B SLC44A4 KLHL29 PKHD1 ACSM2A CMTM7 ACSM2B

2.40e-061861437f28d72b47624b69a580b4429e2be560a26898591
ToppCellCOVID-19-kidney-Mito-rich_PCT|kidney / Disease (COVID-19 only), tissue and cell type

SLC26A3 SLC13A3 SLC6A13 RASGEF1B PKHD1 ACSM2A ACSM2B

2.49e-061871437738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

GRM5 GRM7 PTPRT CNTNAP4 ACSM2A ACSM2B

5.89e-061391436a1945b07f177cde40e7eea03a19236ce76165857
ToppCelldroplet-Fat-Mat-18m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A3 SLC44A4 MEP1A PKHD1 HSD17B2 ABCG5

1.14e-051561436cfd7f56f3155db677684827607e9008e975dbe70
ToppCelldroplet-Fat-Mat-18m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A3 SLC44A4 MEP1A PKHD1 HSD17B2 ABCG5

1.14e-0515614360d79b4172896574b00faf00e87254f68d76f5512
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A12 SLC6A13 DGAT2 HSD17B2 SLC23A1 ABCG5

1.14e-051561436e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCelldroplet-Fat-Mat-18m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A3 SLC44A4 MEP1A PKHD1 HSD17B2 ABCG5

1.14e-051561436f09150aacb6121f913648ed3918f9cd4f22c61f2
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SLC13A3 SLC6A12 SLC6A13 PKHD1 HSD17B2

1.39e-059514353699ea16660a22ea79fecfea56ece2dfb0f13467
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SLC13A3 SLC6A12 SLC6A13 PKHD1 HSD17B2

1.39e-05951435cbfe615d880913bafaf5e7e8d24c3ec14a9351ce
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Nnat_(Nnat)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SLC13A3 SLC6A12 SLC6A13 PKHD1 HSD17B2

1.39e-0595143527ac23b87747434a3084cc087e7b884e68f0eab9
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A MEP1A SLC6A13 AACS HSD17B2 SLC23A1

1.41e-0516214366972d45f4bd4b6522bf93295f7e9dca7c6cba1f3
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLDN14 EVC2 SLC13A3 SLC44A4 ATL1 RPS6KA6

1.41e-0516214362787be283b7a705647058aeb9bc54006ce5ffe95
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A MEP1A SLC6A13 AACS HSD17B2 SLC23A1

1.73e-05168143635ce3b2b9c9997d4c101da5949c7271d6a6b8f12
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLDN14 EVC2 SLC13A3 SLC44A4 ATL1 RPS6KA6

1.85e-0517014368d3c51364a332020810836e2055c60893c10d7f3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MROH2A SLC6A19 SLC13A3 SLC6A13 ACSM2A ACSM2B

1.92e-051711436f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCelldroplet-Tongue-nan-24m-Epithelial-suprabasal_interpapillary|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A19 ATP11B DGAT2 NBEAL2 HSD17B2 PLK3

1.98e-0517214366ece9bb9f31685c918ca4cb7b82cf6ad1cad48af
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A19 SLC13A3 SLC6A13 ACSM2A SLC23A1 ACSM2B

2.05e-0517314368888434641ea554a9b62c436e87920378eef29cd
ToppCellfacs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A SLC44A4 MEP1A SLC6A13 TMEM19 SLC23A1

2.18e-051751436076ad81d6cbeea5512393d192af3ab5aa1f82975
ToppCellfacs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A SLC44A4 MEP1A SLC6A13 TMEM19 SLC23A1

2.18e-051751436445ccb9744a3a9ff37164c532afbe769d306b6c8
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPM6A CYBRD1 MYO5B NBEAL2 ST6GALNAC5 PKHD1

2.33e-0517714369af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC6A19 SLC13A3 SLC6A13 PKHD1 ACSM2A ACSM2B

2.40e-05178143623a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYLK GRM5 GRM7 PKHD1 ACSM2A GPR176

2.40e-051781436544379f5a6145429762258d426b876bb36c112f5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GPM6A SLC13A3 PTPRT SLC6A13 ACSM2A ACSM2B

2.48e-051791436d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYO5B SLC13A3 SLC6A13 PKHD1 ACSM2A ACSM2B

2.56e-051801436358923e4228035a3e90e2957392089219e90dcd7
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYO5B SLC13A3 SLC6A13 PKHD1 ACSM2A ACSM2B

2.56e-051801436864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC6A19 SLC13A3 SLC6A13 PKHD1 ACSM2A ACSM2B

2.64e-0518114366980ea624151da32b7f537f263e40fcb87a02e81
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A19 SLC13A3 SLC6A13 RASGEF1B ACSM2A ACSM2B

2.72e-051821436e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCellControl-Epithelial_alveolar-AT_1-AT1-AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPM6A CYBRD1 MYO5B GALNT13 ST6GALNAC5 PKHD1

2.72e-051821436a95956ce4adccb34cc0c47ebfa1878ce4617904e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NAALAD2 CYBRD1 GRM2 ADGRA2 KLHL29 NALCN

2.72e-051821436b7d532feb73167e05475855061b35a209583f44c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NAALAD2 CYBRD1 GRM2 ADGRA2 KLHL29 NALCN

2.72e-051821436af65f0fc3f9e5d9ce69ee5faaf5b6cb7f8412e0c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A19 SLC13A3 SLC6A13 RASGEF1B ACSM2A ACSM2B

2.72e-05182143657bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A19 SLC13A3 SLC6A12 SLC6A13 ACSM2A ACSM2B

2.81e-051831436facd6dbe0851b537d70a899ac7485714ab27d071
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MROH2A SLC6A19 SLC13A3 SLC6A13 ACSM2A ACSM2B

2.81e-05183143684b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GPM6A SLC13A3 SLC6A12 SLC6A13 ACSM2A ACSM2B

2.81e-05183143685446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MROH2A OBSCN GALNT13 PKHD1 CNTNAP4 EPHA10

2.90e-0518414362cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MROH2A OBSCN GALNT13 PKHD1 CNTNAP4 EPHA10

2.90e-051841436ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MROH2A OBSCN GALNT13 PKHD1 CNTNAP4 EPHA10

2.90e-0518414362b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GPM6A SLC13A3 SLC6A12 SLC6A13 ACSM2A ACSM2B

2.90e-0518414369434731f651820b05335085582960f08fbf895de
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

GPM6A CYBRD1 MYO5B GALNT13 NBEAL2 ST6GALNAC5

2.90e-051841436561592edc3083fad41b91811151b442207c65dd9
ToppCellfacs-Trachea-nan-24m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A FLT1 ADGRG3 ADGRG1 EFNB2 CD200

2.98e-051851436dec60254204014083ff3b4aec0cc75410950a486
ToppCellControl-Epithelial_alveolar|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPM6A CYBRD1 MYO5B GALNT13 ST6GALNAC5 PKHD1

2.98e-0518514363937e026add96a396122139daf8011cfbc60e75c
ToppCellfacs-Trachea-nan-24m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A FLT1 ADGRG3 ADGRG1 EFNB2 CD200

2.98e-051851436201465dc0d7aa0336a36d37805cae1155a5adfe1
ToppCellfacs-Trachea-nan-24m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A FLT1 ADGRG3 ADGRG1 EFNB2 CD200

2.98e-051851436334f006c3ef33338ff8d649309d3f448733a3a99
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A FLT1 RPS6KA2 ITPR2 EFNB2 CD200

3.08e-0518614360ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A19 SLC13A3 SLC6A12 SLC6A13 ACSM2A ACSM2B

3.08e-051861436a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A19 SLC13A3 SLC6A13 PKHD1 ACSM2A ACSM2B

3.08e-0518614365784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRG1 SLC13A3 SLC6A13 PKHD1 ACSM2A ACSM2B

3.17e-0518714363ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCellCOPD-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

GPM6A CYBRD1 SLC40A1 GALNT13 NBEAL2 ST6GALNAC5

3.36e-05189143614e8e57e4db336fbef005270647983b4edf407c0
ToppCellCOVID-19-kidney-PCT-S2|kidney / Disease (COVID-19 only), tissue and cell type

MYO5B SLC13A3 KLHL29 PKHD1 ACSM2A ACSM2B

3.36e-0518914360be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)|Children_(3_yrs) / Lineage, Cell type, age group and donor

TRPM2 SLC40A1 NLRP3 MKNK1 ITPR2 MFSD1

3.46e-051901436f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

GPM6A ADGRG3 EVC2 GDPD5 ACSM2A ACSM2B

3.46e-0519014369ce301841ce9486701fa28eb2a9929e35d476878
ToppCellpdx-Tumor_cells-T8|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CLDN14 DGAT2 HSD17B2 ACSM2A ABCG5 ACSM2B

3.46e-051901436b05db0de9b6ae01dd30074453f7de44f7397631e
ToppCellfacs-Heart-LA-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A FLT1 RPS6KA2 ADGRG1 EFNB2 CD200

3.46e-051901436911b93c4c828ef2d867b91a5eced2dc12a1baf27
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRG1 SLC13A3 SLC6A13 PKHD1 ACSM2A ACSM2B

3.57e-0519114363c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRG1 SLC13A3 SLC6A13 PKHD1 ACSM2A ACSM2B

3.57e-0519114361c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GPM6A MYO5B RPS6KA2 NBEAL2 ST6GALNAC5 PKHD1

3.67e-05192143629f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A19 SLC13A3 SLC6A13 ACSM2A SLC23A1 ACSM2B

3.67e-0519214363e1a4cb0d83efd502c8613d41a1692bdda5860ed
ToppCell(4)_Endothelial_cells|World / Cell class and subclass of bone marrow stroma cells in homeostatis

GPM6A FLT1 ADGRG3 ADGRG1 PIM3 RASGEF1B

3.78e-051931436ae6ba13d4d9f2a700887cdda2790c32007b29ac8
ToppCelldroplet-Fat-Mat-18m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MYLK ADGRG1 PIM3 EFNB2 CD200

3.78e-05193143654024a373e42e1c0bcc327dc084564b83b63a9d4
ToppCelldroplet-Fat-Mat-18m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MYLK ADGRG1 PIM3 EFNB2 CD200

3.78e-05193143681d908594d2983ba7e7c1ec25afdde4315d9690e
ToppCellImmune-interstitial_macrophage_(C1Q_positive)|World / Lineage, Cell type, age group and donor

TRPM2 SLC40A1 NLRP3 MKNK1 ITPR2 MFSD1

3.78e-05193143664d598162a256ac6c9f8280c8a9133661dfbb10f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO5B SLC13A3 SLC6A13 PKHD1 ACSM2A ACSM2B

3.78e-05193143682e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPM6A ADGRG3 RPS6KA2 GDPD5 NALCN ACSM2B

3.78e-051931436bd0027fa97de41ae22ff64a61c8e217496f122ca
ToppCellfacs-Heart-LA-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A FLT1 RPS6KA2 ADGRG1 EFNB2 CD200

3.89e-05194143633cc4f1d716cb71d54cdedbe9bbdc0d7b17c4777
ToppCell(4)_Endothelial_cells-(42)_EC-sinusoidal|World / Cell class and subclass of bone marrow stroma cells in homeostatis

GPM6A FLT1 ADGRG3 ADGRG1 PIM3 RASGEF1B

3.89e-0519414364428b472c2042f88eae028b1770767512a515b75
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

CYBRD1 TRPM2 SLC40A1 NLRP3 ITPR2 NPHP3

3.89e-05194143658046894446cb250814252a23f60fdd59c114d77
ToppCellHSPCs-Mk_prog.|World / Lineage and Cell class

ADGRG3 OBSCN ADGRG1 F2RL2 CMTM7 PLK3

3.89e-0519414365049f4f102844d766eca577e809cf21f7908a9d2
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MYO5B MROH2A SLC44A4 ADGB PLK1 PLK4

4.01e-051951436e525b69145059b66417589601f7109af63730f3a
ToppCellfacs-GAT-Fat-3m-Endothelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A FLT1 ADGRG3 ADGRG1 EFNB2 CD200

4.12e-051961436b6cc1f466d45479764080d34b1daeb8243a5a9f3
ToppCellfacs-GAT-Fat-3m-Endothelial-endothelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A FLT1 ADGRG3 ADGRG1 EFNB2 CD200

4.12e-051961436ede6104cdfa4ee5287efcca9bbc36677cbf7a8d8
ToppCellfacs-GAT-Fat-3m-Endothelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A FLT1 ADGRG3 ADGRG1 EFNB2 CD200

4.12e-051961436039044ab28c53391c34d8226fb8cf78549e63ef4
ToppCellwk_20-22-Hematologic-Myeloid-SPP1+_Mac|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TRPM2 SLC40A1 NLRP3 MKNK1 ITPR2 MFSD1

4.48e-0519914367c19f1b1f4369edd035ca9cdcf4e653771fc4648
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRPM2 SLC40A1 NLRP3 MKNK1 ITPR2 MFSD1

4.48e-051991436f34c15df58fbdc6c90e30800e26fabbf828ad10b
ToppCell5'-Adult-SmallIntestine|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYBRD1 SLC6A19 SLC40A1 MEP1A HSD17B2 ABCG5

4.48e-051991436a5fffe381be1ba7d192b68d1d3937ce47663658e
ToppCellwk_15-18-Hematologic-Myeloid-SPP1+_Mac|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TRPM2 SLC40A1 NLRP3 MKNK1 ITPR2 MFSD1

4.48e-051991436c7fc2ac1601346aac71e7620a8a440fde8d92dbd
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|COVID-19 / Disease (COVID-19 only), tissue and cell type

GRM3 GRM7 PTPRT CNTNAP4 OR51V1

5.84e-05128143591072ca56bce2c552a95edd67e17f43d8cc1de95
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma-2|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

MYLK GRM2 ATL1 ZDHHC23 PLXNB1

6.76e-051321435a8e7e7f38af095d63e221bcc06a1e5147bb6e467
ToppCellCOVID-19-kidney-Technical/muscle_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

FLT1 GRM3 GRM7 PTPRT OR51V1

8.64e-05139143564c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCellControl-Classical_Monocyte-cMono_3|Classical_Monocyte / Disease condition and Cell class

NLRP3 PIM3 RASGEF1B SLC23A1 PLK3

1.09e-041461435fcd8548b42275758d7d77ad2651afe7ad0e5ea2a
ToppCellTCGA-Kidney|World / Sample_Type by Project: Shred V9

SLC6A12 SLC6A13 PKHD1 ACSM2A ACSM2B

1.27e-041511435e31974c0d0a0c644205a0ee6013ab74a09d8a306
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

PKHD1 HTR3B ACSM2A SLC23A1 ACSM2B

1.40e-04154143589a60a79d07466d7ad05888d10a72d3b1ab384af
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

PKHD1 HTR3B ACSM2A SLC23A1 ACSM2B

1.40e-041541435f1fea1a87e977221fa125b62287368be9af4987d
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

PKHD1 HTR3B ACSM2A SLC23A1 ACSM2B

1.40e-041541435b5604c0b0b9b283352a3f612f40883b9123475d1
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal-1|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

PKHD1 HTR3B ACSM2A SLC23A1 ACSM2B

1.40e-041541435160b170a3ade8b246843c9854af332475c047ba0
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM2 NLRP3 SLC6A13 DGAT2 PLK3

1.53e-041571435320d5ac063fd90e26f537475c328b3ae73974bc1
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Myeloid-mast_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM2 NLRP3 SLC6A13 DGAT2 PLK3

1.53e-041571435e4b17c267b754c5af95cdf17f629354d1a8a8ad7
ToppCelldroplet-Lung-LUNG-1m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM2 SLC40A1 NLRP3 SLC6A13 PLK3

1.58e-04158143530cceb73cf5e24b692da84d33342fd3b1ad5efe5
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM2 SLC40A1 NLRP3 SLC6A13 PLK3

1.58e-04158143547793463640f98ee5f680a1ee5786b453355fd57
Drug2-PMPA

NAALAD2 GRM2 GRM3 GRM5 GRM6 GRM7

3.69e-10161406CID010130754
Drugcis-MCG-I

GRM2 GRM3 GRM5 GRM6 GRM7

4.51e-1081405CID003035584
Drug3HPG

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

5.68e-10171406CID000001217
Drugacromelic acid A

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

8.48e-10181406CID000108086
DrugmM PEP

GRM2 GRM3 GRM5 GRM6 GRM7

1.01e-0991405CID005311462
DrugAC1N21PP

GRM2 GRM3 GRM5 GRM6 GRM7

1.01e-0991405CID004014619
Drug1,3-cyclopentanedicarboxylic acid

GRM2 GRM3 GRM5 GRM6 GRM7

1.01e-0991405CID000107216
Drug4-carboxy-3-hydroxyphenylglycine

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

1.75e-09201406CID000001297
DrugNS-105

GRM2 GRM3 GRM5 GRM6 GRM7

2.01e-09101405CID000198695
Drugcyclobutylene AP5

GRM2 GRM3 GRM5 GRM6 GRM7

3.67e-09111405CID000126582
DrugLY341495

NAALAD2 GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

7.65e-09431407CID006324636
DrugMspg

GRM2 GRM3 GRM5 GRM6 GRM7

1.01e-08131405CID003964410
DrugMSOPPE

GRM2 GRM3 GRM5 GRM6 GRM7

1.01e-08131405CID005311463
DrugAC1NSKBB

GRM2 GRM3 GRM5 GRM6 GRM7

1.01e-08131405CID005311256
DrugMTPG

GRM2 GRM3 GRM5 GRM6 GRM7

1.57e-08141405CID005311456
Drug2-methyl-6-styrylpyridine

GRM2 GRM3 GRM5 GRM6 GRM7

1.57e-08141405CID000235382
DrugPBDA

NAALAD2 GRM2 GRM3 GRM5 GRM6 GRM7

2.55e-08301406CID000004408
Drugethylglutamate

GRM2 GRM3 GRM5 GRM6 GRM7

3.38e-08161405CID000014241
Drugalpha-methyl-4-carboxyphenylglycine

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

3.86e-08321406CID000001222
Drug1-aminoindan-1,5-dicarboxylic acid

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

4.69e-08331406CID000002071
Drugazetidine-2,4-dicarboxylic acid

GRM2 GRM3 GRM5 GRM6

4.72e-0871404CID000005370
DrugCPPG

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

5.66e-08341406CID000002878
Drugaminocyclopentane

GRM2 GRM3 GRM5 GRM6 GRM7

8.88e-08191405CID000002906
Drugbenzyloxyaspartate

GRM2 GRM3 GRM5 GRM6 GRM7 SLC6A13

9.64e-08371406CID004133412
DrugL-BMAA

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

1.14e-07381406CID000028558
Drug4CPG

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

1.14e-07381406CID000005115
DrugDETC-MeSO

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

1.34e-07391406CID003035711
Drug3,4-dihydroxyphenylglycine

GRM2 GRM3 GRM5 GRM6 GRM7

1.54e-07211405CID000027915
DrugJoro spider toxin

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

2.45e-07431406CID000119582
DrugMSOP

GRM2 GRM3 GRM5 GRM6 GRM7

2.52e-07231405CID003964633
DrugYM90K

GRIK5 GRM2 GRM3 GRM5 GRM6

2.52e-07231405CID005486547
DrugCGP 39653

GRIK5 GRM2 GRM3 GRM5 GRM6

3.17e-07241405CID006437837
DrugRS)-2-chloro-5-hydroxyphenylglycine

GRM2 GRM3 GRM5 GRM6 GRM7

3.17e-07241405CID003645780
DrugAC1L1D63

NAALAD2 GRM2 GRM3 GRM5 GRM6

3.94e-07251405CID000002209
Druggavestinel

GRIK5 GRM2 GRM3 GRM5 GRM6

3.94e-07251405CID006450546
DrugAC1NQH9B

GRM2 GRM3 GRM5 GRM6 GRM7

4.85e-07261405CID005221504
DrugL-689,560

GRIK5 GRM2 GRM3 GRM5 GRM6

5.92e-07271405CID000121918
DrugL-CCG-I

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

6.17e-07501406CID000001271
DrugAMN082

GRM2 GRM5 GRM6 GRM7

6.52e-07121404CID001894360
DrugLY354740

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

6.96e-07511406CID000114827
DrugC-PP

GRIK5 GRM2 GRM3 GRM5 GRM6

7.18e-07281405CID000001228
Drugaptiganel

GRIK5 GRM2 GRM3 GRM5 GRM6

7.18e-07281405CID000060839
DrugAC1L1EKQ

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

7.83e-07521406CID000002834
DrugAC1NUW3V

GRIK5 GRM2 GRM3 GRM5 GRM6

8.63e-07291405CID005462126
Drugketobemidone

GRIK5 GRM2 GRM3 GRM5 GRM6

8.63e-07291405CID000010101
DrugN-Ac-D-E

NAALAD2 GRM2 GRM3 GRM5 GRM6 GRM7

8.79e-07531406CID000005255
DrugAC1L1BXF

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7 SLC6A13

9.46e-07851407CID000001650
Drugcis-2,3-piperidine dicarboxylic acid

GRIK5 GRM2 GRM3 GRM5 GRM6

1.03e-06301405CID000001226
DrugGYKI 53655

GRIK5 GRM2 GRM3 GRM5 GRM6

1.03e-06301405CID000126757
DrugAC1L32TU

GRIK5 GRM2 GRM3 GRM5 GRM6

1.03e-06301405CID000107831
DrugNPC 12626

GRIK5 GRM2 GRM3 GRM5 GRM6

1.22e-06311405CID000108099
DrugLY235959

GRIK5 GRM2 GRM3 GRM5 GRM6

1.22e-06311405CID000131938
Drugeliprodil

GRIK5 GRM2 GRM3 GRM5 GRM6

1.22e-06311405CID000060703
DrugGYKI 52466

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

1.51e-06581406CID000003538
DrugMPEP

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

1.67e-06591406CID003025961
DrugTG-3

GRIK5 GRM2 GRM3 GRM5 GRM6

1.69e-06331405CID000205489
Drug3,5-dihydroxyphenylglycine

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

1.85e-06601406CID000108001
DrugD-CPPene

GRIK5 GRM2 GRM3 GRM5 GRM6

1.97e-06341405CID006435801
Drugpyrrolidine-2,4-dicarboxylate

GRM2 GRM3 GRM5 GRM6 GRM7 SLC6A13

2.04e-06611406CID000003868
DrugDMeOB

GRM2 GRM5 GRM6

2.26e-0651403CID002061047
DrugAcamprosate

GRM2 GRM3 GRM5

2.26e-0651403DB00659
DrugLY393675

GRM2 GRM5 GRM6

2.26e-0651403CID005311262
Drugtyrphostin B52

GRM2 GRM5 GRM6

2.26e-0651403CID005328773
Drug1m5d

GRM2 GRM3 GRM5 GRM6 GRM7

2.29e-06351405CID000447082
DrugR,S)-AMPA

GRIK5 GRM2 GRM3 GRM5 GRM6

2.65e-06361405CID000001221
DrugC6H12NO5P

GRIK5 GRM2 GRM3 GRM5 GRM6

2.65e-06361405CID000104962
Druggacyclidine

GRIK5 GRM2 GRM3 GRM5 GRM6

2.65e-06361405CID000176265
Drugglutamic acid diethyl ester

GRIK5 GRM2 GRM3 GRM5 GRM6

2.65e-06361405CID000073960
DrugCGS 19755

GRIK5 GRM2 GRM3 GRM5 GRM6

3.49e-06381405CID000068736
Drug4-aminopyrrolidine-2,4-dicarboxylate

GRM2 GRM3 GRM5 GRM6 GRM7

3.98e-06391405CID003331970
DrugHA-966

GRIK5 GRM2 GRM3 GRM5 GRM6

3.98e-06391405CID000001232
DrugAC1MBZ3L

GRM2 GRM5 GRM6

4.49e-0661403CID002733524
DrugMTEP

GRM2 GRM5 GRM6

4.49e-0661403CID009794218
DrugSIB-1757

GRM2 GRM5 GRM6

4.49e-0661403CID006304902
DrugAspartylglutamate

NAALAD2 GRM2 GRM3 GRM5 GRM6

4.53e-06401405CID000151403
Drugfelbamate

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

4.61e-06701406CID000003331
DrugLY382884

GRIK5 GRM2 GRM3 GRM5

4.94e-06191404CID000656723
DrugL000369

GRM2 GRM3 GRM5 GRM6 GRM7

5.13e-06411405CID003931705
DrugAC1NNRU4

GRM2 GRM3 GRM5 GRM6 GRM7

5.13e-06411405CID005126051
Drugbutenafine

GRM2 GRM3 GRM5 GRM6 GRM7

5.80e-06421405CID000002484
DrugAC1L1DME

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

6.90e-06751406CID000002414
Drug2-amino-3-phosphonopropionic acid

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

7.45e-06761406CID000003857
DrugCX546

GRIK5 GRM2 GRM3 GRM5

7.56e-06211404CID000002890
Drugcyclizine

MYO5B GRM2 GRM3 GRM5 GRM7 LRP8 NOD1

7.63e-061161407CID000006726
DrugMCCG-I

GRM2 GRM5 GRM6

7.82e-0671403CID005311457
DrugCDPPB

GRM2 GRM5 GRM6

7.82e-0671403CID011245456
Drug7-chlorokynurenic acid

GRIK5 GRM2 GRM3 GRM5 GRM6

8.20e-06451405CID000001884
Drugcysteine sulfinic acid

GRM2 GRM3 GRM5 GRM6 GRM7

9.16e-06461405CID000000109
Drugnifedipine

CYBRD1 MYLK MYO5B GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7 SLC40A1 NLRP3 CYP2U1

1.02e-0541514012CID000004485
Drugphorbol 12,13-diacetate

GRM2 GRM3 GRM5 GRM6 GRM7

1.13e-05481405CID000072293
Drugavermectin

GRIK5 GRM2 GRM3 GRM5 GRM6

1.13e-05481405CID006450460
DrugIno-Hcy

SLC26A3 CYBRD1 GRM2 GRM3 GRM5 GRM6

1.24e-05831406CID000193585
Drugmethylenecyclopropylglycine

GRM2 GRM3 GRM5 GRM6 GRM7

1.26e-05491405CID000441452
Drug5,7-dichlorokynurenic acid

GRIK5 GRM2 GRM3 GRM5 GRM6

1.26e-05491405CID000001779
DrugD-N-Q

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

1.33e-05841406CID000003140
Drugmemantine

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

1.52e-05861406CID000004054
DrugIPSP

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

1.63e-05871406CID000022083
Drugpicrotoxin

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7 SLC6A13 HTR3B

1.67e-051811408CID000031304
Drughexachlorophene

GRIK5 GRM2 GRM3 GRM5 GRM6 GRM7

1.98e-05901406CID000003598
DrugNBQX

HTR6 GRIK5 GRM2 GRM3 GRM5 GRM6

1.98e-05901406CID003272523
DiseaseSchizophrenia

GPM6A AHI1 GPR50 HTR6 MYO5B GRIK5 GRM2 GRM3 GRM5 GRM7 LRP8 SLC6A12 EFNB2 NPS HTR3B

6.36e-0688312715C0036341
DiseaseX-21319 measurement

ACSM2A ACSM2B

1.84e-0521272EFO_0800807
DiseaseBipolar Disorder

GPR50 RPS6KA2 TRPM2 GRIK5 GRM3 GRM5 GRM7 TAAR6 SLC6A13 HTR3B

4.30e-0547712710C0005586
DiseaseX-11478 measurement

ACSM2A ACSM2B

5.50e-0531272EFO_0021242
Diseasehereditary spastic paraplegia 3A (implicated_via_orthology)

ATL1 ATL2

5.50e-0531272DOID:0110791 (implicated_via_orthology)
DiseaseAddicted to cocaine

GRM2 GRM3

5.50e-0531272C0858355
DiseaseCoffin-Lowry syndrome (implicated_via_orthology)

RPS6KA2 RPS6KA6

1.10e-0441272DOID:3783 (implicated_via_orthology)
DiseaseEpilepsy, Benign Psychomotor, Childhood

GRM2 GRM3 GRM5

1.29e-04231273C0393672
DiseaseEpilepsy, Lateral Temporal

GRM2 GRM3 GRM5

1.29e-04231273C0393682
DiseaseUncinate Epilepsy

GRM2 GRM3 GRM5

1.29e-04231273C0014558
DiseaseEpilepsy, Temporal Lobe

GRM2 GRM3 GRM5

1.29e-04231273C0014556
Diseasepreeclampsia, fetal genotype effect measurement

FLT1 ITPR2

1.82e-0451272EFO_0000668, EFO_0007959
Disease3-hydroxyhexanoate measurement

ACSM2A ACSM2B

1.82e-0451272EFO_0800378
Diseaseserum metabolite measurement

NAALAD2 SLC13A3 GRIK5 MFSD4B GRM7 ZP3 PTPRT ATL1 SLC6A12 SLC6A13 ACSM2A EPHA10 ACSM2B

2.26e-0494512713EFO_0005653
Diseaseindoleacetoylcarnitine measurement

ACSM2A ACSM2B

2.73e-0461272EFO_0800106
Diseaseindolepropionate measurement

DNA2 ACSM2A

2.73e-0461272EFO_0021016
DiseaseIron Overload

CYBRD1 SLC40A1

3.81e-0471272C0282193
DiseaseAutosomal Recessive Polycystic Kidney Disease

NPHP3 PKHD1

6.49e-0491272C0085548
DiseaseR-warfarin measurement

GPM6A MYO5B GRM7 MKNK1 KLHL29 MRGPRX3

1.04e-032651276EFO_0803324
DiseaseAlcoholic Intoxication, Chronic

GRM2 GRM3 GRM7 LRP8 NPS HTR3B

1.10e-032681276C0001973
DiseaseCiliopathies

AHI1 EVC2 NPHP3 PKHD1

1.33e-031101274C4277690
Diseaseovary epithelial cancer (is_marker_for)

PLK1 PLK3

1.39e-03131272DOID:2152 (is_marker_for)
DiseaseDrug habituation

GRM5 GRM7 MKNK1 PRPF4

1.57e-031151274C0013170
DiseaseDrug abuse

GRM5 GRM7 MKNK1 PRPF4

1.57e-031151274C0013146
DiseasePrescription Drug Abuse

GRM5 GRM7 MKNK1 PRPF4

1.57e-031151274C4316881
DiseaseSubstance-Related Disorders

GRM5 GRM7 MKNK1 PRPF4

1.57e-031151274C0236969
DiseaseDrug Use Disorders

GRM5 GRM7 MKNK1 PRPF4

1.57e-031151274C0013222
DiseaseDrug Dependence

GRM5 GRM7 MKNK1 PRPF4

1.57e-031151274C1510472
DiseaseSubstance Dependence

GRM5 GRM7 MKNK1 PRPF4

1.57e-031151274C0038580
DiseaseSubstance Use Disorders

GRM5 GRM7 MKNK1 PRPF4

1.57e-031151274C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

GRM5 GRM7 MKNK1 PRPF4

1.57e-031151274C0029231
DiseaseSubstance abuse problem

GRM5 GRM7 MKNK1 PRPF4

1.62e-031161274C0740858
DiseaseSpastic Paraplegia, Hereditary

ATL1 CYP2U1

1.62e-03141272C0037773
DiseasePsychoses, Substance-Induced

HTR6 GRM2

2.40e-03171272C0033941
Diseaseamino acid measurement

SETX RPS6KA2 GRIK5 GRM5 GRM7 KLHL29 SLC6A12 SLC6A13 OR1P1

2.72e-036781279EFO_0005134
Diseasepulmonary non-tuberculous mycobacterial infection

FLT1 TRPM2

3.00e-03191272MONDO_0018469
Diseasefumarate measurement

RPS6KA2 SLC13A3

3.66e-03211272EFO_0010480
DiseasePsychoses, Drug

HTR6 GRM2

3.66e-03211272C0033937
DiseaseSeckel syndrome

DNA2 PLK4

4.01e-03221272C0265202
DiseaseAttention Deficit Disorder

GRM5 GRM7

4.01e-03221272C0041671
DiseaseMinimal Brain Dysfunction

GRM5 GRM7

4.01e-03221272C1321905
Diseaseage at onset, Myopia

FLT1 MYO5B GPR101 GRM7

4.09e-031501274EFO_0004847, HP_0000545
DiseaseMajor Depressive Disorder

GRM5 GRM7 LRP8 SLC6A13 HTR3B

4.09e-032431275C1269683
DiseaseAmphetamine-Related Disorders

HTR6 MYO5B GRM2

4.20e-03751273C0236733
DiseaseAmphetamine Abuse

HTR6 MYO5B GRM2

4.20e-03751273C0236807
DiseaseAmphetamine Addiction

HTR6 MYO5B GRM2

4.20e-03751273C0236804
Diseaseurinary metabolite measurement

NAALAD2 RPS6KA2 SLC6A13 AACS ACSM2A

4.24e-032451275EFO_0005116

Protein segments in the cluster

PeptideGeneStartEntry
WITRAMYQECGSRLL

ACTL10

226

Q5JWF8
LFDVLTWLGYCNSTM

HTR6

301

P50406
MYSLHSWVGLIAVIC

CYBRD1

116

Q53TN4
MTSSDILLCYTTVGW

AACS

321

Q86V21
ELVVTGCYDSMIRIW

AHI1

711

Q8N157
LCSELMRWIISEIYA

ADGB

131

Q8N7X0
ALVTTHFLYLAMWAC

ADGRA2

1021

Q96PE1
LFMLGIYTITLCSLW

HTR3B

421

O95264
CTLWGTQMSSRTLYI

ACSM2A

11

Q08AH3
FIGFTMYTTCIIWLA

GRM2

761

Q14416
IGFTMYTTCIIWLAF

GRM3

771

Q14832
LLYCNMTETAWTIIQ

CNTNAP4

621

Q9C0A0
SLELCWFREGTTMYA

ADGRG3

416

Q86Y34
LACMDTWVYEGTVFL

OR2L3

186

Q8NG85
LVLSLSTMHVFWCYP

NPS

11

P0C0P6
LLWIAVAICTSMLFF

ITPR2

2266

Q14571
TCRRWMALDYAGISI

PAQR3

136

Q6TCH7
LYNAIMSSWVCSLLV

OR8D1

131

Q8WZ84
CGLLVLASWTMSALY

OR7A5

141

Q15622
LYTVAMNPRLCWSLV

OR9I1

131

Q8NGQ6
LLCLMGVATSYAVWA

MFSD10

121

Q14728
YTLIMNWRVCTVLAS

OR2A12

131

Q8NGT7
YNSLMSWRVCTVLAV

OR2A14

131

Q96R47
ATDMWSIGVICYILV

MYLK

1641

Q15746
FTMYTTCIIWLAFVP

GRM5

776

P41594
SCDLWSLGVIIYVML

MAPKAPK5

221

Q8IW41
MALCYSAAWDARVIT

NEMF

596

O60524
LLGNFMVLWSTCRTT

GPR176

56

Q14439
TCGRCVSAWFIMLTY

GPM6A

121

P51674
WVRVMPSLAYCTFLL

G6PC3

141

Q9BUM1
VVIMFTWSGLACLIF

SLC43A1

196

O75387
SVRNTCIYLVITWIM

GPR50

141

Q13585
YCWGVLMVLCRTAIS

EFNB2

11

P52799
WMTLCIAEYSLIVNT

PCNX4

181

Q63HM2
LLTNWMSICLYTFVR

PLXNB1

1686

O43157
LACMDTWVYEGTVFL

OR2L8

186

Q8NGY9
LYVYMWLGSVECLLL

OR2W1

101

Q9Y3N9
WLGSVECLLLAVMSY

OR2W1

106

Q9Y3N9
LTWVALIFCILYMIS

OR51I1

26

Q9H343
CMGLSTVYTVLGILW

OR51V1

81

Q9H2C8
TFIWMLRCIYETQSQ

NOD1

651

Q9Y239
VLTWAALFLMVRYQC

EVC2

311

Q86UK5
GLYVCWLTIRAVTVM

MARCHF6

681

O60337
WIAMCLLGLSYSLLA

MFSD1

356

Q9H3U5
YCLMWVTADLVSFTL

GDPD5

496

Q8WTR4
ESCDLWSLGVILYTM

RPS6KA5

601

O75582
AACDIWSLGVLFYTM

RPS6KA6

601

Q9UK32
LWYVVSMASDCRVFL

LCN15

36

Q6UWW0
RYLSSVMCVLLWALS

MRGPRX3

136

Q96LB0
SVMSVLAIWRRPCSY

EPHA10

581

Q5JZY3
LCSMIWGASPSYTIL

GPR101

181

Q96P66
LYLLLSLCMGWTIVR

GPR180

256

Q86V85
YLAIMTWRVCITLAV

OR2A7

131

Q96R45
LYYSTIMTQRVCLWL

OR2D3

146

Q8NGH3
WFNRLSYLVATEICM

RASGEF1B

261

Q0VAM2
CLWIATSVYGASMAT

MFSD4B

321

Q5TF39
WRLVFDYNCSSVVML

PTPRT

1261

O14522
YTVIMSWRVCTILVL

OR2A2

131

Q6IF42
YLAIMTWRVCITLAV

OR2A4

131

O95047
YSLVWVMAAVVLCTA

CD200

16

P41217
LWMLFFRTRSICTTV

F2RL2

116

O00254
LVTCGLVWATVFLYM

F2RL2

211

O00254
YCKVVLATSLMWVLV

GALNT13

6

Q8IUC8
IWAMGVISYLSLTCS

OBSCN

6646

Q5VST9
GVSWAMLVARTCQLY

PAPOLA

246

P51003
TTTNSLLWCLLYMSL

CYP2U1

356

Q7Z449
ISLMSFSWCANYIRS

CERS3

216

Q8IU89
GFTMYTTCIIWLAFV

GRM6

786

O15303
MGLTLITLCTWAYIR

ATL1

481

Q8WXF7
LTAVSYLKGLWMECV

CLDN14

41

O95500
GILTFIWVLMFLCTA

FITM2

196

Q8N6M3
ILATLMSCTRSVYSW

EIF3D

251

O15371
LVMGLALIFLCTWAY

ATL2

506

Q8NHH9
VVATMIFSSVCYWTL

ABCG5

476

Q9H222
MCWIRDSLVSYITNL

ADGRG1

561

Q9Y653
MSGWRYLICVSFLLT

ITIH6

1

Q6UXX5
GFTMYTTCIVWLAFI

GRM7

791

Q14831
TFVLLLICIAYWAMT

SLC44A4

361

Q53GD3
VWLFMLLAYLAVSCV

GRIK5

546

Q16478
THLEYFSLWCLMLTL

DNA2

436

P51530
WGLILFSVSCFLMYT

HSD17B2

56

P37059
CLFVILLMAVYWCTE

SLC13A3

41

Q8WWT9
GMLTLGCTLYIVWAT

BVES

71

Q8NE79
IVWATLYRCALDIMI

BVES

81

Q8NE79
LMYIFCTDCWLIAVL

DGAT2

91

Q96PD7
VIALLCMSGYLIWRN

LRP8

836

Q14114
YSVIMTWRVCITLAV

OR2A1;

131

Q8NGT9
YSTIMTWKVCITLAL

OR2A25

131

A4D2G3
LRYNIIMNSSTCIWV

OR9A2

126

Q8NGT5
RCDLWSLGVVLYIML

MKNK1

281

Q9BUB5
HYTTIMSPRSCIWLI

OR1A1

131

Q9P1Q5
ACWTLTSLLAMTRTF

OR1P1

161

Q8NH06
SGMTTEFWVRLLCYI

MROH2A

516

A6NES4
EWMGLLEYLSRISIC

NLRP3

116

Q96P20
SCLIRMDLLYWQFTI

SND1-IT1

11

Q9HBX3
MLFAIYFLCIITSTW

TAS2R19

236

P59542
LLCAVYFLSIMISVW

TAS2R31

236

P59538
LLCAIYFLSIMISVW

TAS2R43

236

P59537
LLCAIYFLSIIMSVW

TAS2R46

236

P59540
IYLMSGSHDCSIRLW

STRN3

736

Q13033
LACAWSVLYMCTIRG

SLC6A19

201

Q695T7
GLMYLRSWAVLTCNV

TMC3

591

Q7Z5M5
ICISVSWILPLMYSG

TAAR6

151

Q96RI8
WTFLTSLIHSLYKMC

NPHP3

796

Q7Z494
LIATCSYDRTFKLWM

PRPF4

506

O43172
YLISGSRDTTCMVWR

NBEAL2

2516

Q6ZNJ1
MAWIRSTCILFFTLL

MEP1A

1

Q16819
TSFGLMLTSYIASCW

PITRM1

441

Q5JRX3
YSIGWFLALSSMVCV

SLC6A12

536

P48065
VLISWGCIIYASMVS

SMIM27

21

A0A1B0GUW7
SYWLGICMLLTILEE

SETX

236

Q7Z333
LTMYHGWVLTSCYIL

SLC40A1

121

Q9NP59
LSTGWFTMTIALELC

ST6GALNAC5

231

Q9BVH7
ALLVGTCTEMRYISW

PKHD1

2266

P08F94
KYDCLIWIMTFIFTI

SLC26A3

466

P40879
ESDVWSLGCMFYTLL

PLK4

191

O00444
CTLWGTQMSSRTLYI

ACSM2B

11

Q68CK6
TFLCMASIWLSYKIS

CMTM7

151

Q96FZ5
RFDQVMTWSSALLYC

CLEC20A

166

Q6ZU45
SAWFAIILMVVTCLF

ATP11B

1071

Q9Y2G3
ADVWSLGCVMYTLLC

PLK3

241

Q9H4B4
CRLAYSLWSQLVMLL

AGPAT3

51

Q9NRZ7
LRWVLSFGMCSSALV

SLC37A3

111

Q8NCC5
IMTVWLLCYVLTLTD

SLC23A1

261

Q9UHI7
FLWALVISTCLEFSM

TRA

6

P0DTU3
AIYLWLFSLVCEEMR

TRPM2

831

O94759
CIVATAVMWAAALYF

SIDT1

746

Q9NXL6
SMVCIPAWSLYRLGT

SLC6A13

541

Q9NSD5
YSSWTLFTCEIEMLL

NUP188

536

Q5SRE5
ATVWSLGVLLYDMVC

PIM3

226

Q86V86
SFTCVWYSVIITAGM

ZDHHC23

351

Q8IYP9
QYSASWMCLSLLAAL

TMEM19

166

Q96HH6
VLTSLQWTLMTYVCD

ZBED6

676

P86452
LFSLMTCLISYWVTL

SLC30A6

71

Q6NXT4
FLWALVISTCLEFSM

TRAV38-2DV8

6

A0JD32
AQTWTMLRIIYCSPG

WDR24

446

Q96S15
LLICSASLDYVIMWN

WDR27

86

A2RRH5
VLRLLTSMYFQCWAV

TMC2

661

Q8TDI7
MVSYWDTGVLLCALL

FLT1

1

P17948
MELSYRLFICLLLWG

ZP3

1

P21754
AMWLSRLFTVYCSAL

TMEM33

26

P57088
EVDVWSIGCIMYTLL

PLK1

231

P53350
SGVTLADVWCYMSLL

KLHL29

646

Q96CT2
YIRSCRVLMLSDWYT

JKAMP

116

Q9P055
ACDIWSLGILLYTML

RPS6KA2

591

Q15349
TYLDWVMIIVTICSC

NALCN

886

Q8IZF0
GRLYLWMCLAAALAS

NAALAD2

6

Q9Y3Q0
MSVGELYSQCTRVWI

MYO5B

1

Q9ULV0