Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glycogen phosphorylase activity	PYGB PYGL PYGM	2.01e-07	3	118	3	GO:0008184
GeneOntologyMolecularFunction	1,4-alpha-oligoglucan phosphorylase activity	PYGB PYGL PYGM	1.99e-06	5	118	3	GO:0004645
GeneOntologyMolecularFunction	translation elongation factor activity	EIF5A2 EIF5AL1 EIF5A	2.13e-04	20	118	3	GO:0003746
GeneOntologyBiologicalProcess	positive regulation of translational termination	EIF5A2 EIF5AL1 EIF5A	7.09e-07	4	117	3	GO:0045905
GeneOntologyBiologicalProcess	response to organophosphorus	AKAP6 SELL FOS CFTR ITPR3 P2RY11 PYGM PCK1	1.50e-06	142	117	8	GO:0046683
GeneOntologyBiologicalProcess	positive regulation of translational elongation	EIF5A2 EIF5AL1 EIF5A	1.76e-06	5	117	3	GO:0045901
GeneOntologyBiologicalProcess	response to purine-containing compound	AKAP6 SELL FOS CFTR ITPR3 P2RY11 PYGM PCK1	4.82e-06	166	117	8	GO:0014074
GeneOntologyBiologicalProcess	regulation of translational termination	EIF5A2 EIF5AL1 EIF5A	1.46e-05	9	117	3	GO:0006449
GeneOntologyBiologicalProcess	response to cAMP	AKAP6 FOS CFTR ITPR3 PYGM PCK1	1.90e-05	97	117	6	GO:0051591
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	SOX6 PATZ1 FOS APBB1 NKX2-3 GLIS3 REL ASH2L RAX KMT2C SIRT2 ZNF544 ARID2 TET1 EIF5A MED12L CHD6 CREB3L3 CAMTA1 PCK1 MED13	3.30e-05	1390	117	21	GO:0045944
GeneOntologyBiologicalProcess	regulation of translational elongation	EIF5A2 EIF5AL1 EIF5A	6.19e-05	14	117	3	GO:0006448
GeneOntologyBiologicalProcess	positive regulation of inorganic anion transmembrane transport	CFTR SLC34A1	9.54e-05	3	117	2	GO:1903797
GeneOntologyBiologicalProcess	positive regulation of oocyte maturation	BNC1 SIRT2	9.54e-05	3	117	2	GO:1900195
GeneOntologyBiologicalProcess	translational termination	EIF5A2 EIF5AL1 EIF5A	1.14e-04	17	117	3	GO:0006415
GeneOntologyBiologicalProcess	regulation of inorganic anion transmembrane transport	CFTR SLC34A1	1.90e-04	4	117	2	GO:1903795
GeneOntologyBiologicalProcess	cellular response to cAMP	AKAP6 CFTR ITPR3 PCK1	2.32e-04	53	117	4	GO:0071320
GeneOntologyBiologicalProcess	positive regulation of cell differentiation	AKAP6 SOX6 ARHGAP32 RELN FOS CFTR TIAM2 BNC1 EIF5AL1 OTP SIRT2 ARID2 CD36 FRZB EIF5A SOCS1 PCK1	2.39e-04	1141	117	17	GO:0045597
Domain	IF5A_HYPUSINE	EIF5A2 EIF5AL1 EIF5A	2.40e-07	3	117	3	PS00302
Domain	Transl_elong_IF5A_C	EIF5A2 EIF5AL1 EIF5A	2.40e-07	3	117	3	IPR020189
Domain	PHOSPHORYLASE	PYGB PYGL PYGM	2.40e-07	3	117	3	PS00102
Domain	Transl_elong_IF5A	EIF5A2 EIF5AL1 EIF5A	2.40e-07	3	117	3	IPR001884
Domain	Glycg_phsphrylas	PYGB PYGL PYGM	2.40e-07	3	117	3	IPR011833
Domain	eIF-5a	EIF5A2 EIF5AL1 EIF5A	2.40e-07	3	117	3	PF01287
Domain	Glyco_trans_35	PYGB PYGL PYGM	2.40e-07	3	117	3	IPR000811
Domain	Phosphorylase	PYGB PYGL PYGM	2.40e-07	3	117	3	PF00343
Domain	Trans_elong_IF5A_hypusine_site	EIF5A2 EIF5AL1 EIF5A	2.40e-07	3	117	3	IPR019769
Domain	eIF-5a	EIF5A2 EIF5AL1 EIF5A	2.40e-07	3	117	3	SM01376
Domain	Translation_prot_SH3-like	EIF5A2 EIF5AL1 EIF5A	1.53e-04	17	117	3	IPR008991
Domain	Rib_L2_dom2	EIF5A2 EIF5AL1 EIF5A	1.83e-04	18	117	3	IPR014722
Domain	-	EIF5A2 EIF5AL1 EIF5A	1.83e-04	18	117	3	2.30.30.30
Domain	HMGI_Y	PATZ1 KMT2C	2.32e-04	4	117	2	PS00354
Domain	WxxW_domain	MUC5B MUC2	5.74e-04	6	117	2	IPR025155
Domain	Mucin2_WxxW	MUC5B MUC2	5.74e-04	6	117	2	PF13330
Domain	BIR	XIAP BIRC6	1.06e-03	8	117	2	PF00653
Domain	BIR_REPEAT_2	XIAP BIRC6	1.06e-03	8	117	2	PS50143
Domain	BIR	XIAP BIRC6	1.06e-03	8	117	2	SM00238
Domain	-	XIAP BIRC6	1.06e-03	8	117	2	1.10.1170.10
Domain	BIR_rpt	XIAP BIRC6	1.06e-03	8	117	2	IPR001370
Domain	BIR_REPEAT_1	XIAP BIRC6	1.06e-03	8	117	2	PS01282
Pathway	REACTOME_HYPUSINE_SYNTHESIS_FROM_EIF5A_LYSINE	EIF5A2 EIF5AL1 EIF5A	1.75e-06	5	80	3	MM14823
Pathway	KEGG_MEDICUS_REFERENCE_GLYCOGEN_DEGRADATION	PYGB PYGL PYGM	1.44e-05	9	80	3	M47621
Pathway	REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS	PYGB PYGL PYGM	6.12e-05	14	80	3	M19193
Pubmed	Human eIF5A2 on chromosome 3q25-q27 is a phylogenetically conserved vertebrate variant of eukaryotic translation initiation factor 5A with tissue-specific expression.	EIF5A2 EIF5AL1 EIF5A	4.11e-08	3	121	3	11161802
Pubmed	New K50R mutant mouse models reveal impaired hypusination of eif5a2 with alterations in cell metabolite landscape.	EIF5A2 EIF5AL1 EIF5A	4.11e-08	3	121	3	36848144
Pubmed	Differential expression of eIF5A-1 and eIF5A-2 in human cancer cells.	EIF5A2 EIF5AL1 EIF5A	4.11e-08	3	121	3	16519677
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	AKAP6 ERMP1 LRRK1 AGAP11 DZIP1 KEAP1 ADGRV1 TIAM2 KMT2C TET1 MED12L WDR90 MED13	4.43e-08	529	121	13	14621295
Pubmed	Localization of the muscle, liver, and brain glycogen phosphorylase genes on linkage maps of mouse chromosomes 19, 12, and 2, respectively.	FOS PYGB PYGL PYGM	1.85e-07	15	121	4	2575583
Pubmed	Biological Relevance and Therapeutic Potential of the Hypusine Modification System.	EIF5A2 EIF5AL1 EIF5A	4.09e-07	5	121	3	26037925
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	AKAP6 ADGRV1 BIRC6 KMT2C PHLDB1 SIK2 CHD6 CAMTA1	1.30e-06	225	121	8	12168954
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ARHGAP32 APBB1 ZDBF2 ASH2L ITPR3 RAB3GAP1 PHLDB1 CADM1 ARID2 GLS SERPINB1 CHD6	2.49e-06	638	121	12	31182584
Pubmed	Characterising the dynamics of placental glycogen stores in the mouse.	ERVW-1 PYGB PYGL PYGM	3.09e-06	29	121	4	32798765
Pubmed	Quantitative study of the interactome of PKCζ involved in the EGF-induced tumor cell chemotaxis.	DOCK4 RANBP6 DZIP1 KEAP1 EIF5A PYGB UTRN	3.93e-06	184	121	7	23402259
Pubmed	Modulation of Apoptosis Controls Inhibitory Interneuron Number in the Cortex.	SOX6 RELN FOS	8.83e-06	12	121	3	29444425
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	AKAP6 GLIS3 DZIP1 BIRC6 ASH2L MED12L INTS4 PYGM UTRN MED13	9.97e-06	497	121	10	23414517
Pubmed	Comparison of Human Eukaryotic Translation Initiation Factors 5A1 and 5AL1: Identification of Amino Acid Residues Important for EIF5A1 Lysine 50 Hypusination and Its Protein Stability.	EIF5AL1 EIF5A	1.20e-05	2	121	2	37047039
Pubmed	Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation.	EIF5AL1 EIF5A	1.20e-05	2	121	2	31130465
Pubmed	Abnormal expression of Muc5b in Cftr-null mice and in mammary tumors of MMTV-ras mice.	CFTR MUC5B	1.20e-05	2	121	2	22005837
Pubmed	The N-terminal region of eukaryotic translation initiation factor 5A signals to nuclear localization of the protein.	EIF5AL1 EIF5A	1.20e-05	2	121	2	17707773
Pubmed	Proteomic analysis of ubiquitin-proteasome effects: insight into the function of eukaryotic initiation factor 5A.	EIF5AL1 EIF5A	1.20e-05	2	121	2	12894223
Pubmed	CB1 Activity Drives the Selection of Navigational Strategies: A Behavioral and c-Fos Immunoreactivity Study.	FOS CNR1	1.20e-05	2	121	2	32041135
Pubmed	DOCK4 stimulates MUC2 production through its effect on goblet cell differentiation.	DOCK4 MUC2	1.20e-05	2	121	2	33559155
Pubmed	FAT/CD36 regulates PEPCK expression in adipose tissue.	CD36 PCK1	1.20e-05	2	121	2	23302781
Pubmed	Upregulation of Anti-Oxidative Stress Response Improves Metabolic Changes in L-Selectin-Deficient Mice but Does Not Prevent NAFLD Progression or Fecal Microbiota Shifts.	SELL KEAP1	1.20e-05	2	121	2	34298930
Pubmed	Nuclear localized protein-1 (Nulp1) increases cell death of human osteosarcoma cells and binds the X-linked inhibitor of apoptosis protein.	XIAP TCF25	1.20e-05	2	121	2	18068114
Pubmed	CHD6 regulates the topological arrangement of the CFTR locus.	CFTR CHD6	1.20e-05	2	121	2	25631877
Pubmed	Exosomal EIF5A derived from Lewis lung carcinoma induced adipocyte wasting in cancer cachexia.	EIF5AL1 EIF5A	1.20e-05	2	121	2	37743008
Pubmed	Independent roles of eIF5A and polyamines in cell proliferation.	EIF5AL1 EIF5A	1.20e-05	2	121	2	15377278
Pubmed	Sequence determination and cDNA cloning of eukaryotic initiation factor 4D, the hypusine-containing protein.	EIF5AL1 EIF5A	1.20e-05	2	121	2	2492279
Pubmed	Targeted inhibition of eIF5Ahpu suppresses tumor growth and polarization of M2-like tumor-associated macrophages in oral cancer.	EIF5AL1 EIF5A	1.20e-05	2	121	2	37653021
Pubmed	Epstein Barr virus-mediated transformation of B cells from XIAP-deficient patients leads to increased expression of the tumor suppressor CADM1.	XIAP CADM1	1.20e-05	2	121	2	36270981
Pubmed	Identification of a new member of the human eIF-5A gene family.	EIF5AL1 EIF5A	1.20e-05	2	121	2	7622067
Pubmed	Cannabinoid receptor type 1 (CB1R) signaling regulates hepatic gluconeogenesis via induction of endoplasmic reticulum-bound transcription factor cAMP-responsive element-binding protein H (CREBH) in primary hepatocytes.	CREB3L3 CNR1	1.20e-05	2	121	2	21693703
Pubmed	Eukaryotic initiation factor 5A is a cellular target of the human immunodeficiency virus type 1 Rev activation domain mediating trans-activation.	EIF5AL1 EIF5A	1.20e-05	2	121	2	8253832
Pubmed	[Interleukin-1beta induces MUC2/MUC5B gene expression in human nasal epithelial cells].	MUC5B MUC2	1.20e-05	2	121	2	20873538
Pubmed	Isoform-selective regulation of glycogen phosphorylase by energy deprivation and phosphorylation in astrocytes.	PYGB PYGM	1.20e-05	2	121	2	25130497
Pubmed	Eukaryotic initiation factor 4D. Purification from human red blood cells and the sequence of amino acids around its single hypusine residue.	EIF5AL1 EIF5A	1.20e-05	2	121	2	3095320
Pubmed	Homology modelling of the human eukaryotic initiation factor 5A (eIF-5A).	EIF5AL1 EIF5A	1.20e-05	2	121	2	11742107
Pubmed	The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice.	EIF5AL1 EIF5A	1.20e-05	2	121	2	20501948
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	RBM4B PATZ1 ASH2L KMT2C TET1 INTS4	1.28e-05	146	121	6	23892456
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	AKAP6 NRDE2 GBP7 XIAP COPG2 ASH2L TIAM2 KMT2C THOP1 GLG1 TET1 CRYBG1 CAMTA1 UTRN	2.57e-05	1084	121	14	11544199
Pubmed	An endocannabinoid system is present in the mouse olfactory epithelium but does not modulate olfaction.	ITPR3 CNR1	3.59e-05	3	121	2	26037800
Pubmed	Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation.	EIF5AL1 EIF5A	3.59e-05	3	121	2	36893894
Pubmed	Map positions of four dinucleotide repeats in the mouse t complex.	LMF1 ITPR3	3.59e-05	3	121	2	1643311
Pubmed	Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development.	EIF5AL1 EIF5A	3.59e-05	3	121	2	21850436
Pubmed	Cystic fibrosis transmembrane conductance regulator contributes to reacidification of alkalinized lysosomes in RPE cells.	CFTR LAMP1	3.59e-05	3	121	2	22572847
Pubmed	Anti-apoptotic proteins in the autophagic world: an update on functions of XIAP, Survivin, and BRUCE.	XIAP BIRC6	3.59e-05	3	121	2	32019552
Pubmed	Combined lipase deficiency (cld): a lethal mutation on chromosome 17 of the mouse.	LMF1 ITPR3	3.59e-05	3	121	2	6857276
Pubmed	The type 1 cannabinoid receptor is highly expressed in embryonic cortical projection neurons and negatively regulates neurite growth in vitro.	RELN CNR1	3.59e-05	3	121	2	18973587
Pubmed	Identification and characterization of eukaryotic initiation factor 5A-2.	EIF5A2 EIF5A	3.59e-05	3	121	2	14622290
Pubmed	The role of polyamines in supporting growth of mammalian cells is mediated through their requirement for translation initiation and elongation.	EIF5AL1 EIF5A	3.59e-05	3	121	2	20181941
Pubmed	Evidences of a role for eukaryotic translation initiation factor 5A (eIF5A) in mouse embryogenesis and cell differentiation.	EIF5AL1 EIF5A	3.59e-05	3	121	2	20458750
Pubmed	Subcellular localization of the hypusine-containing eukaryotic initiation factor 5A by immunofluorescent staining and green fluorescent protein tagging.	EIF5AL1 EIF5A	3.59e-05	3	121	2	12210765
Pubmed	Mucin gene polymorphisms in otitis media patients.	MUC5B MUC2	3.59e-05	3	121	2	19718741
Pubmed	Deoxyhypusine synthase mutations alter the post-translational modification of eukaryotic initiation factor 5A resulting in impaired human and mouse neural homeostasis.	EIF5AL1 EIF5A	3.59e-05	3	121	2	37333770
Pubmed	Microbial-induced meprin β cleavage in MUC2 mucin and a functional CFTR channel are required to release anchored small intestinal mucus.	CFTR MUC2	3.59e-05	3	121	2	25114233
Pubmed	Molecular modeling in the age of clinical genomics, the enterprise of the next generation.	CFTR XIAP	3.59e-05	3	121	2	28204942
Pubmed	Pure curcumin increases the expression of SOCS1 and SOCS3 in myeloproliferative neoplasms through suppressing class I histone deacetylases.	HDAC8 SOCS1	3.59e-05	3	121	2	23430957
Pubmed	Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.	EIF5AL1 EIF5A	3.59e-05	3	121	2	32817651
Pubmed	Characteristics of rodent intestinal mucin Muc3 and alterations in a mouse model of human cystic fibrosis.	CFTR MUC2	3.59e-05	3	121	2	11352827
Pubmed	Inhibiting eukaryotic initiation factor 5A (eIF5A) hypusination attenuated activation of the SIK2 (salt-inducible kinase 2)-p4E-BP1 pathway involved in ovarian cancer cell proliferation and migration.	EIF5A SIK2	3.59e-05	3	121	2	37219665
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DOCK4 MAGI1 ARHGAP32 PATZ1 APBB1 XIAP DZIP1 POLR1F PHLDB1 TET1 SIK2 UTRN	4.88e-05	861	121	12	36931259
Pubmed	A human MAP kinase interactome.	MAGI1 ARHGAP32 RBM4B FOS DDX27 KMT2C RTKN2 ARID2 CHD6	5.35e-05	486	121	9	20936779
Pubmed	Comment on "constitutive nuclear localization of NFAT in Foxp3(+) regulatory T cells independent of calcineurin activity".	FOS REL	7.17e-05	4	121	2	23125425
Pubmed	HtrA2 cleaves Apollon and induces cell death by IAP-binding motif in Apollon-deficient cells.	XIAP BIRC6	7.17e-05	4	121	2	15781261
Pubmed	IAPs: more than just inhibitors of apoptosis proteins.	XIAP BIRC6	7.17e-05	4	121	2	18414036
Pubmed	Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.	MUC5B MUC2	7.17e-05	4	121	2	25638393
Pubmed	Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.	MUC5B MUC2	7.17e-05	4	121	2	22269464
Pubmed	Voltage drives diverse endocannabinoid signals to mediate striatal microcircuit-specific plasticity.	RGS9 CNR1	7.17e-05	4	121	2	23892554
Pubmed	Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.	MUC5B MUC2	7.17e-05	4	121	2	23807779
Pubmed	Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies.	EIF5A2 EIF5A	7.17e-05	4	121	2	22927971
Pubmed	DHPS-dependent hypusination of eIF5A1/2 is necessary for TGFβ/fibronectin-induced breast cancer metastasis and associates with prognostically unfavorable genomic alterations in TP53.	EIF5A2 EIF5A	7.17e-05	4	121	2	31558321
Pubmed	The post-translational synthesis of a polyamine-derived amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF5A).	EIF5A2 EIF5A	7.17e-05	4	121	2	16452303
Pubmed	Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.	MUC5B MUC2	7.17e-05	4	121	2	17471237
Pubmed	The mouse secreted gel-forming mucin gene cluster.	MUC5B MUC2	7.17e-05	4	121	2	14984930
Pubmed	Activation of cannabinoid receptor type 1 (Cb1r) disrupts hepatic insulin receptor signaling via cyclic AMP-response element-binding protein H (Crebh)-mediated induction of Lipin1 gene.	CREB3L3 CNR1	7.17e-05	4	121	2	22989885
Pubmed	The genomic structure encoding human initiation factor eIF-5A.	EIF5AL1 EIF5A	7.17e-05	4	121	2	7545941
Pubmed	The eukaryotic cofactor for the human immunodeficiency virus type 1 (HIV-1) rev protein, eIF-5A, maps to chromosome 17p12-p13: three eIF-5A pseudogenes map to 10q23.3, 17q25, and 19q13.2.	EIF5AL1 EIF5A	7.17e-05	4	121	2	7759117
Pubmed	Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.	MUC5B MUC2	7.17e-05	4	121	2	29869461
Pubmed	Polymorphisms in MUC1, MUC2, MUC5B and MUC6 genes are not associated with the risk of chronic atrophic gastritis.	MUC5B MUC2	7.17e-05	4	121	2	21596555
Pubmed	MicroRNA-29a induces loss of 5-hydroxymethylcytosine and promotes metastasis of hepatocellular carcinoma through a TET-SOCS1-MMP9 signaling axis.	TET1 SOCS1	7.17e-05	4	121	2	28661477
Pubmed	Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.	MUC5B MUC2	7.17e-05	4	121	2	12676567
Pubmed	SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation.	COPG2 DDX27 PYGB PYGL	7.54e-05	64	121	4	26511642
Pubmed	Analysis of a lung defect in autophagy-deficient mouse strains.	PYGB PYGL PYGM	1.01e-04	26	121	3	24275123
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	COPG2 ZDBF2 KEAP1 BIRC6 GLS TET1 CHD6 UTRN	1.12e-04	418	121	8	34709266
Pubmed	Polymorphism of human mucin genes in chest disease: possible significance of MUC2.	MUC5B MUC2	1.19e-04	5	121	2	11062147
Pubmed	Monomerization of cytosolic mature smac attenuates interaction with IAPs and potentiation of caspase activation.	XIAP BIRC6	1.19e-04	5	121	2	20957035
Pubmed	Differential expression of MUC genes in endometrial and cervical tissues and tumors.	MUC5B MUC2	1.19e-04	5	121	2	16188033
Pubmed	Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility.	DIO3 SOCS1	1.19e-04	5	121	2	20724312
Pubmed	Comprehensive glycomics comparison between colon cancer cell cultures and tumours: implications for biomarker studies.	MUC5B MUC2	1.19e-04	5	121	2	24840470
Pubmed	Impaired neonatal survival of pro-opiomelanocortin null mutants.	PYGL PCK1	1.19e-04	5	121	2	21184805
Pubmed	Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer.	KEAP1 GLS	1.19e-04	5	121	2	35504291
Pubmed	Neuron-specific ablation of eIF5A or deoxyhypusine synthase leads to impairments in growth, viability, neurodevelopment, and cognitive functions in mice.	EIF5AL1 EIF5A	1.19e-04	5	121	2	34688659
Pubmed	Constitutive nuclear localization of NFAT in Foxp3+ regulatory T cells independent of calcineurin activity.	FOS REL	1.19e-04	5	121	2	22490438
Pubmed	Regional localization of loci on chromosome 14 using somatic cell hybrids.	FOS PYGL	1.19e-04	5	121	2	8275705
Pubmed	Identification and characterization of a novel human PP1 phosphatase complex.	ASH2L PPP1R8 KMT2C	1.72e-04	31	121	3	20516061
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	DOCK4 ARHGAP32 APBB1 ZDBF2 BIRC6 EIF5AL1 RAB3GAP1 GLG1 GLS EIF5A TCF25 PYGB COIL	1.74e-04	1139	121	13	36417873
Pubmed	The cannabinoid-1 receptor is abundantly expressed in striatal striosomes and striosome-dendron bouquets of the substantia nigra.	RGS9 CNR1	1.78e-04	6	121	2	29466446
Pubmed	L-selectin ligation-induced CSF-1 gene transcription is regulated by AP-1 in a c-Abl kinase-dependent manner.	SELL FOS	1.78e-04	6	121	2	18619508
Pubmed	Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.	MUC5B MUC2	1.78e-04	6	121	2	19110483
Pubmed	Histone deacetylases inhibitor sodium butyrate inhibits JAK2/STAT signaling through upregulation of SOCS1 and SOCS3 mediated by HDAC8 inhibition in myeloproliferative neoplasms.	HDAC8 SOCS1	1.78e-04	6	121	2	23111066
Pubmed	Polymeric black tea polyphenols induce phase II enzymes via Nrf2 in mouse liver and lungs.	FOS KEAP1	1.78e-04	6	121	2	18358244
Pubmed	DNA-methyltransferase1 (DNMT1) binding to CpG rich GABAergic and BDNF promoters is increased in the brain of schizophrenia and bipolar disorder patients.	RELN TET1	1.78e-04	6	121	2	25476119
GeneFamily	Glycogen phosphorylases	PYGB PYGL PYGM	8.66e-08	3	81	3	437
GeneFamily	Ring finger proteins\|Baculoviral IAP repeat containing\|Caspase recruitment domain containing	XIAP BIRC6	5.45e-04	8	81	2	419
Coexpression	MATSUDA_NATURAL_KILLER_DIFFERENTIATION	SOX6 MAGI1 FOS XIAP LRRK1 BNC1 EIF5AL1 CADM1 CD36 EIF5A SERPINB1 PPIH	5.41e-06	520	121	12	MM1008
Coexpression	WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_UP	CFTR LAMP1 DDX27 PHLDB1 PYGB PCK1	1.44e-05	113	121	6	M1260
Coexpression	MATSUDA_NATURAL_KILLER_DIFFERENTIATION	SOX6 MAGI1 FOS XIAP LRRK1 BNC1 CADM1 CD36 EIF5A SERPINB1 PPIH	1.62e-05	486	121	11	M18517
Coexpression	TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_DN	REL MARF1 SERPINB1 CRYBG1	2.82e-05	38	121	4	M17812
Coexpression	IVANOVA_HEMATOPOIESIS_STEM_CELL	ARHGAP32 ZDBF2 IGDCC4 TCF25 PYGM CAMTA1 PCK1	3.27e-05	193	121	7	M6813
Coexpression	IVANOVA_HEMATOPOIESIS_STEM_CELL	ARHGAP32 ZDBF2 IGDCC4 TCF25 PYGM CAMTA1 PCK1	3.61e-05	196	121	7	MM667
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	ARFGEF1 REL BIRC6 KMT2C ARID2 GLS UTRN MED13	4.81e-08	188	121	8	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GLIS3 LRRK1 RTKN2 CDH22 SEMA6D MED12L UTRN	4.81e-07	173	121	7	9a2d42f8d9cb834856522661d524abb91c4637c5
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_2\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	MAGI1 MUC5B TIAM2 CADM1 TET1 EIF5A PCK1	6.05e-07	179	121	7	d95367d689732ab2653e8d70d8d8e5eb15ae6eef
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L2-4_RORB_GRIK1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LMF1 GLIS3 RTKN2 CDH22 SEMA6D FRZB UTRN	6.51e-07	181	121	7	57994ff4ecffb15653aee00644d9f887f5e3461d
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX6 RELN SLC24A3 RGS9 CDA UTRN	2.75e-06	144	121	6	71107275767a0728541a3695715c44874b3e5efc
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX6 RELN RGS9 PTCHD4 SEMA6D UTRN	3.10e-06	147	121	6	50e86860a94be103092c40e39a172eac92372f0d
ToppCell	E16.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	REXO5 FOS EIF5A2 ERMP1 SERPINB1 PYGL	3.90e-06	153	121	6	6a2a2379238133ce0ad714af130ffe02dd317247
ToppCell	E16.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	REXO5 FOS EIF5A2 ERMP1 SERPINB1 PYGL	3.90e-06	153	121	6	faa442dd925b2b09919e93c492ccc3f19803ad24
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX6 RELN SLC24A3 RGS9 CDA UTRN	5.05e-06	160	121	6	0bfdaf979e6f128cba2928ce16bca4d3deff8ac9
ToppCell	wk_15-18-Hematologic-Myeloid-CMP\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SELL AZU1 M1AP SERPINB1 PYGL CREB3L3	6.68e-06	168	121	6	9fc9c93ab7513bf4dfefc866b97c703208a238c9
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GLIS3 LRRK1 RTKN2 CDH22 SEMA6D UTRN	6.91e-06	169	121	6	319cba07263bf41fcbcbfecd117f91b729394241
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOS M1AP BNC1 PYGM LRRN4 MYO15A	7.39e-06	171	121	6	e780e63510ca47036bc36ca40ecff4098596ee9e
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AKAP6 ZDBF2 SLC47A2 BNC1 SERPINB1 LRRN4	9.59e-06	179	121	6	adf8b025032a03dbb58871a92025cd7efbeb22ff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN CFTR MUC5B ADGRV1 MYO15A CNTN1	1.12e-05	184	121	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN CFTR MUC5B ADGRV1 MYO15A CNTN1	1.12e-05	184	121	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN CFTR MUC5B ADGRV1 MYO15A CNTN1	1.12e-05	184	121	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 CFTR ADGRV1 ITPR3 CADM1 CD36	1.23e-05	187	121	6	5df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	SOX6 CFTR ADGRV1 ITPR3 CADM1 CD36	1.31e-05	189	121	6	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	renal_cortex_nuclei-Adult_normal_reference\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	LMF1 FAM135B GLG1 SIK2 TCF25 LDLRAD4	1.31e-05	189	121	6	a48df46274d51e84ffb40264646de7346104efb9
ToppCell	renal_medulla_nuclei-Adult_normal_reference\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 MAGI1 FOS CADM1 UTRN LDLRAD4	1.35e-05	190	121	6	f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SOX6 MAGI1 CFTR ADGRV1 CADM1 CD36	1.39e-05	191	121	6	34cc997e4e5c727495f321e6807a84aa124da486
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	MAGI1 CFTR ADGRV1 ITPR3 CADM1 CD36	1.43e-05	192	121	6	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 CFTR ADGRV1 ITPR3 CADM1 CD36	1.43e-05	192	121	6	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	wk_15-18-Hematologic-Myeloid-Promonocyte-like\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SELL AZU1 SERPINB1 CRYBG1 CDA MTFR2	1.56e-05	195	121	6	37b4f635b71734c6e0bc808a739af4bbe6bb47f6
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOS BNC1 FRZB PYGM LRRN4 MYO15A	1.61e-05	196	121	6	429de4119c8b2193c992d36a6af84f806730cbee
ToppCell	COVID-19-kidney-TAL\|kidney / Disease (COVID-19 only), tissue and cell type	DZIP1 ADGRV1 ITPR3 CADM1 SEMA6D PYGB	1.61e-05	196	121	6	04f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOS BNC1 FRZB PYGM LRRN4 MYO15A	1.61e-05	196	121	6	8c8a73d9d9581b8d9a9babfa93459d12fb9eb3ac
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK4 MAGI1 ARHGAP32 GLIS3 ADGRV1 CADM1	1.70e-05	198	121	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	MAGI1 ARHGAP32 BIRC6 KMT2C UTRN LDLRAD4	1.75e-05	199	121	6	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFTR ADGRV1 ITPR3 CADM1 GLS CNR1	1.75e-05	199	121	6	2dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1-FILIP1L\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GLIS3 LRRK1 CDH22 SEMA6D MED12L UTRN	1.80e-05	200	121	6	f6af5ef02625aaae21e885e1ebd195e34731e53a
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1-FILIP1L-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GLIS3 LRRK1 CDH22 SEMA6D MED12L UTRN	1.80e-05	200	121	6	53f61e28c3ad6399f63c54e06120ecb5ebbf90d9
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1-FILIP1L--L3-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	GLIS3 LRRK1 CDH22 SEMA6D MED12L UTRN	1.80e-05	200	121	6	c1f243ae929f7791e040437470033abf749b44cc
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX6 RELN RGS9 CDA UTRN	2.35e-05	125	121	5	d05556ea185c15815a4f8643f1c01185badbeece
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Myh4\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX6 RELN RGS9 CDA UTRN	2.73e-05	129	121	5	f83187c0bb06528127b8d2d56674ab1946846951
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4/8-lo-Trm_Tgd\|Lung / Manually curated celltypes from each tissue	RBM4B APBB1 RGS9 ADGRV1 LDLRAD4	4.32e-05	142	121	5	c3db15bcb305ebdf5c9ca0b5c8ce63fab978590b
ToppCell	COVID-19_Convalescent-Classical_Monocyte\|COVID-19_Convalescent / Disease condition and Cell class	SELL FOS CD36 SERPINB1	4.45e-05	72	121	4	73db21be480920fc936f3a965495f5cf004e350a
ToppCell	PND03-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SELL ERMP1 MED12L PYGL CDA	6.16e-05	153	121	5	489228ab81c3ae339a53a9da6c2a1c1b6ac3f84b
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX6 RELN RGS9 CDA UTRN	6.96e-05	157	121	5	741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFTR OFCC1 MUC5B ADGRV1 PTCHD4	7.62e-05	160	121	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFTR OFCC1 MUC5B ADGRV1 PTCHD4	7.62e-05	160	121	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	metastatic_Brain-B_lymphocytes-Undetermined\|metastatic_Brain / Location, Cell class and cell subclass	SELL REL TIAM2 LDLRAD4 CNR1	8.31e-05	163	121	5	4eac7fd8acdb7f09ce739335f22a879f9b8febfb
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFTR GLIS3 ADGRV1 CRYBG1 PCK1	8.56e-05	164	121	5	d6f71d804bb65301c02ea4e6673e20688b5fcd5b
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SELL ERMP1 M1AP SERPINB1 PPIH	8.81e-05	165	121	5	ba68090d79e2243af2bdee0c27a32e65f540f8ac
ToppCell	356C-Epithelial_cells-Epithelial-D_(AT2)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	CFTR M1AP A2ML1 WDR90 LRRN4	9.06e-05	166	121	5	2e4cb4056e6b0c43290a5588ff525f5f05b8beee
ToppCell	facs-Kidney-nan-3m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELL REL ITPR3 SERPINB1 CNTN1	9.06e-05	166	121	5	6a948aefd283a2572da37b59dbc142b6e686b024
ToppCell	facs-Kidney-nan-3m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELL REL ITPR3 SERPINB1 CNTN1	9.06e-05	166	121	5	8d0c4eb90a2c006f96ae61d3d94c96fb64bc0c4d
ToppCell	356C-Epithelial_cells-Epithelial-D_(AT2)\|356C / Donor, Lineage, Cell class and subclass (all cells)	CFTR M1AP A2ML1 WDR90 LRRN4	9.06e-05	166	121	5	eb8d972326a734549675307e411fc795af66da70
ToppCell	Control\|World / group, cell type (main and fine annotations)	MAGI1 FOS ADGRV1 RTKN2 CADM1	9.59e-05	168	121	5	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FOS RGS9 CRYBG1 SOCS1 LRRN4	9.59e-05	168	121	5	07be11b6f0f37106e219692db5795c6dd32807c9
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	DOCK4 MAGI1 ADGRV1 RTKN2 CADM1	1.01e-04	170	121	5	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_D3\|367C / Donor, Lineage, Cell class and subclass (all cells)	SELL FOS NKX2-3 REL SOCS1	1.01e-04	170	121	5	7a8b90ff37c5b3b31820924a3e7f4ce20319f896
ToppCell	facs-Diaphragm-Limb_Muscle-18m-Endothelial-new-cluster\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	M1AP CADM1 SEMA6D CD36 ATP4A	1.01e-04	170	121	5	4fb4ce46e4fa2418238e264875209d7ebe844d82
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX6 RELN RGS9 CDA UTRN	1.01e-04	170	121	5	8ab67e2b6e30fdf9e9a2c02e31d4df34e751a3ed
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	SOX6 CFTR BNC1 LRRN4 PCK1	1.10e-04	173	121	5	e05cddf5bf63cf419343ff229453327519765be8
ToppCell	AT1_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	MAGI1 RTKN2 CADM1 GLS UTRN	1.10e-04	173	121	5	3afca2a429c634af0220c1aa19ce4cf4ee3e8b3e
ToppCell	367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|367C / Donor, Lineage, Cell class and subclass (all cells)	SOX6 CFTR BNC1 LRRN4 PCK1	1.10e-04	173	121	5	74ad5ed33821b8816c9c8e67c50ee4496ba18e2f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ERMP1 DZIP1 ADGRV1 SLC47A2 MED12L	1.13e-04	174	121	5	46bd0ef7d0541386de7a901d85d53d0176dc92bf
ToppCell	AT1-AT2_cells-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	APBB1 ERVW-1 RTKN2 PHLDB1 SEMA6D	1.16e-04	175	121	5	bdd85ba280648a0283c1984662a34c7b840f64dd
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_RORB_CARTPT\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GLIS3 LRRK1 RTKN2 CDH22 MED12L	1.32e-04	180	121	5	5e78b29fa1cbdcf502fee3577e5b45766b90d1dc
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AKAP6 DZIP1 ADGRV1 CADM1 SEMA6D	1.32e-04	180	121	5	9e09b3dfe344b5d50520711513d389865d73a861
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 CFTR GLIS3 ADGRV1 SEMA6D	1.32e-04	180	121	5	b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	MAGI1 CFTR GLIS3 ADGRV1 SERPINB1	1.36e-04	181	121	5	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	COVID-19-kidney-CD-IC-B\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SOX6 MAGI1 CFTR CDH22 CDA	1.39e-04	182	121	5	ee6a8c356bbbdae55e4ea858337e079491f9f4aa
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	REXO5 PATZ1 CDH22 TET1 COIL	1.39e-04	182	121	5	d1c3cc2942faec7527a3c25869fd65c17899e5e4
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	REXO5 PATZ1 CDH22 TET1 COIL	1.39e-04	182	121	5	92f83f29e358000cd86a709eb8b6199761ffe8bd
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	REXO5 PATZ1 CDH22 TET1 COIL	1.39e-04	182	121	5	02baca9a72c7b559c3e452693b3b134af804c868
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Etv1_\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX6 RELN RGS9 CDA	1.42e-04	97	121	4	f3c3fb260954f594a9ab8e1ac9a01115767cbc7a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAGI1 DZIP1 ADGRV1 CADM1 SEMA6D	1.43e-04	183	121	5	31ab55d5f3639f5964541d5eae23044dbda3356e
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 CFTR ADGRV1 CADM1 CD36	1.43e-04	183	121	5	6847c1252d6bb105524f812658112517fd351eab
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LMF1 CDH22 FRZB ATP4A CNR1	1.47e-04	184	121	5	30fddbc9696476d4d7f08e53f84ea994a4ed873a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LMF1 CDH22 FRZB ATP4A CNR1	1.47e-04	184	121	5	96926efa220f03d0787322c9519bb9e8f64f74d0
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SOX6 ARHGAP32 CFTR ADGRV1 CD36	1.51e-04	185	121	5	0d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	REL ZDBF2 TIAM2 GLS LDLRAD4	1.51e-04	185	121	5	e913c64f9b4873443d88dce270f0b7b6d1b4cbce
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	REXO5 ZDBF2 CFAP65 CD36 PYGB	1.51e-04	185	121	5	05bc89a566b0db90ae06506e067190a4739a0974
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	MAGI1 RTKN2 CADM1 SEMA6D LRRN4	1.51e-04	185	121	5	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAGI1 DZIP1 ADGRV1 CADM1 SEMA6D	1.51e-04	185	121	5	898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCell	10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Mega-Mast\|bone_marrow / Manually curated celltypes from each tissue	SLC24A3 ADGRV1 MED12L PYGL WDR90	1.51e-04	185	121	5	a62ebaff92f2ed27b27b32c27c89cfbe2cb35116
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-lymphatic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RELN PTCHD4 CD36 FRZB CDA	1.54e-04	186	121	5	5d94e6dd2c92e0c46badeb1e6eb54b69af855a66
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	AKAP6 ARHGAP32 AGAP11 PHLDB1 CADM1	1.54e-04	186	121	5	f73cb91e74a806858650ae97f543fc779ba4cff8
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	AKAP6 ARHGAP32 AGAP11 PHLDB1 CADM1	1.54e-04	186	121	5	8694ca16c9780729f4fba67ba20e35745f1eb4e9
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	REL BIRC6 RAB3GAP1 ARID2 MARF1	1.54e-04	186	121	5	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RELN PTCHD4 CD36 FRZB CDA	1.54e-04	186	121	5	1da52e13096dfe4eb08bd0e7461cb3809b3b3deb
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC24A3 IGDCC4 SEMA6D CD36 CNR1	1.58e-04	187	121	5	02105c82a9ba79d2f19e002188377fc3440770c2
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CFTR AGAP11 RAX RTKN2	1.60e-04	100	121	4	60c2bdee5d37dedf9be1e03b6b52b539a2277df3
ToppCell	COPD-Epithelial-ATII\|COPD / Disease state, Lineage and Cell class	MAGI1 CFTR GLIS3 ADGRV1 CADM1	1.62e-04	188	121	5	eb6d79d733b53f64ca615bb777c64ed456866549
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DZIP1 ADGRV1 CADM1 SEMA6D CNTN1	1.62e-04	188	121	5	3cee9916399e2e7580cecbcbb27424a71e7e7ac0
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CFTR AGAP11 RAX RTKN2	1.66e-04	101	121	4	de49feca7548640f85d206ebc56a58ab0bf7ac16
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DZIP1 ADGRV1 ITPR3 SEMA6D CNTN1	1.66e-04	189	121	5	e059be2965cca70ff5576df055d0af1775b76e00
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APBB1 ADGRV1 PHLDB1 SIRT2 SERPINB1	1.66e-04	189	121	5	bab0fe55643d3ee750355a32b1ff6634fa5cf88d
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	SOX6 MAGI1 CADM1 SEMA6D UTRN	1.66e-04	189	121	5	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 CFTR ADGRV1 CADM1 CD36	1.70e-04	190	121	5	8aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_monocytic-intermediate_monocyte\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	AZU1 ARFGEF1 SERPINB1 PYGL CDA	1.70e-04	190	121	5	896b5825edb30fe62cbbed6078570c1f8057a99e
ToppCell	ILEUM\|World / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FOS REL CRYBG1 SOCS1 LDLRAD4	1.70e-04	190	121	5	4395dbd18c14d491f5066a2ddac438a16b1fd7c3
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SOX6 MAGI1 CADM1 CD36 CRYBG1	1.75e-04	191	121	5	3e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	AZU1 MED12L SERPINB1 PYGL CDA	1.75e-04	191	121	5	6c1283d51a845cff67ed5e500f7e944165297b53
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 CFTR ADGRV1 CADM1 CD36	1.75e-04	191	121	5	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FOS GLIS3 ERMP1 ADGRV1 CADM1	1.75e-04	191	121	5	2fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCell	ILEUM-non-inflamed\|ILEUM / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FOS NKX2-3 SEMA6D CD36 PCK1	1.75e-04	191	121	5	c4a78ef7b87ffadbb1b9b69cbfa7c164ca456f9a
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 CFTR ADGRV1 ITPR3 CADM1	1.75e-04	191	121	5	ca5669bd6f4a17471acae3eb229f845cc2e08efa
Drug	galocitabine	PYGB PYGL PYGM CDA	6.86e-10	4	118	4	CID000065950
Drug	5-trifluoromethyl-2'-deoxycytidine	PYGB PYGL PYGM CDA	3.41e-09	5	118	4	CID000125618
Drug	2,2-dimethyl-3-hydroxybutyric acid	CFTR PYGB PYGL PYGM	1.02e-08	6	118	4	CID000152984
Drug	3,5-dimethylphenyl isocyanate	PYGB PYGL PYGM	1.36e-07	3	118	3	CID000521488
Drug	5'-deoxy-5'-fluoro-5'-(methylthio)adenosine	PYGB PYGL PYGM	1.36e-07	3	118	3	CID000147839
Drug	NSC758405	PYGB PYGL PYGM	1.36e-07	3	118	3	CID000003201
Drug	3,5-dinitrophenyl phosphate	PYGB PYGL PYGM	1.36e-07	3	118	3	CID000151920
Drug	pyridoxal phosphoglucose	PYGB PYGL PYGM	1.36e-07	3	118	3	CID000196007
Drug	5-ethyl-4-hydroxy-2-methyl-3(2H)-furanone	PYGB PYGL PYGM	1.36e-07	3	118	3	CID000093111
Drug	adenosine-5'-chloromethylphosphonate	PYGB PYGL PYGM	1.36e-07	3	118	3	CID000191554
Drug	hydan	PYGB PYGL PYGM	1.36e-07	3	118	3	CID000008360
Drug	EHMF	PYGB PYGL PYGM	1.36e-07	3	118	3	CID000033931
Drug	pyridoxal 5'-methylenephosphonate	PYGB PYGL PYGM	1.36e-07	3	118	3	CID003082249
Drug	Plp 5'-mpa	PYGB PYGL PYGM	1.36e-07	3	118	3	CID003082151
Drug	glucose-1,2-cyclic phosphate	PYGB PYGL PYGM	1.36e-07	3	118	3	CID000191723
Drug	3'-FFdUrd	PYGB PYGL PYGM	1.36e-07	3	118	3	CID000072260
Drug	2',3',4',5,5'-pentachloro-2-biphenylol	PYGB PYGL PYGM	1.36e-07	3	118	3	CID000119518
Drug	AC1L8XK3	PYGB PYGL PYGM	1.36e-07	3	118	3	CID000409735
Drug	N-acetyl-N'-beta-D-glucopyranosyl urea	PYGB PYGL PYGM	1.36e-07	3	118	3	CID000446801
Drug	riboflavin tetraacetate	PYGB PYGL PYGM	1.36e-07	3	118	3	CID000094186
Drug	2,5-dimethyl-3-furanone	PYGB PYGL PYGM	1.36e-07	3	118	3	CID000085730
Drug	3,5-dinitrophenol	PYGB PYGL PYGM	1.36e-07	3	118	3	CID000011459
Drug	5-deoxyribose-1-phosphate	PYGB PYGL PYGM	5.41e-07	4	118	3	CID000135786
Drug	ingliforib	PYGB PYGL PYGM	5.41e-07	4	118	3	CID006451325
Drug	uric acid riboside	PYGB PYGL PYGM	5.41e-07	4	118	3	CID000164933
Drug	pseudo-dl-glucose	PYGB PYGL PYGM	5.41e-07	4	118	3	CID000125259
Drug	pyridoxal diphosphate	PYGB PYGL PYGM	5.41e-07	4	118	3	CID000125696
Drug	2,5-anhydro-D-mannitol 1-phosphate	PYGB PYGL PYGM	5.41e-07	4	118	3	CID000189134
Drug	AC1LAMW2	PYGB PYGL PYGM	5.41e-07	4	118	3	CID000491364
Drug	FdUrd-C8	PYGB PYGL PYGM	5.41e-07	4	118	3	CID000094262
Drug	Mem-CC	PYGB PYGL PYGM	5.41e-07	4	118	3	CID003081269
Drug	BCIp4A	PYGB PYGL PYGM	5.41e-07	4	118	3	CID000192417
Drug	3'-chloromethotrexate	PYGB PYGL PYGM	5.41e-07	4	118	3	CID000097703
Drug	Gvapspat amide	ITPR3 PYGB PYGL PYGM	8.95e-07	15	118	4	CID000125015
Drug	AC1L19E7	ADGRV1 CD36 PYGB PYGL PYGM	1.31e-06	37	118	5	CID000000509
Drug	heptulose-2-P	PYGB PYGL PYGM	1.35e-06	5	118	3	CID000124823
Drug	6-FPLP	PYGB PYGL PYGM	1.35e-06	5	118	3	CID000146246
Drug	gluconohydroximo-1,5-lactone	PYGB PYGL PYGM	1.35e-06	5	118	3	CID009576855
Drug	DHPBU	PYGB PYGL PYGM	1.35e-06	5	118	3	CID000125914
Drug	5'-isobutylthioinosine	PYGB PYGL PYGM	1.35e-06	5	118	3	CID003080910
Drug	indirubin-5-sulphonate	PYGB PYGL PYGM	1.35e-06	5	118	3	CID005288641
Drug	AC1LCUXJ	PYGB PYGL PYGM	1.35e-06	5	118	3	CID000656425
Drug	6-amino-5-bromouracil	PYGB PYGL PYGM	1.35e-06	5	118	3	CID000080578
Drug	etafenone	PYGB PYGL PYGM	1.35e-06	5	118	3	CID000003275
Drug	ddEtUrd	PYGB PYGL PYGM	1.35e-06	5	118	3	CID000451452
Drug	m-anisidine	PYGB PYGL PYGM	1.35e-06	5	118	3	CID000010824
Drug	2-hydroxypropylphosphonate	PYGB PYGL PYGM	1.35e-06	5	118	3	CID000441028
Drug	6-FDPL	PYGB PYGL PYGM	1.35e-06	5	118	3	CID000129578
Drug	3'-O-methylpyridoxal 5'-phosphate	PYGB PYGL PYGM	1.35e-06	5	118	3	CID003082179
Drug	GlcMan	PYGB PYGL PYGM	1.35e-06	5	118	3	CID000152120
Drug	U66985	PYGB PYGL PYGM	1.35e-06	5	118	3	CID000127224
Drug	AC1O3M08	PYGB PYGL PYGM	1.35e-06	5	118	3	CID006331955
Drug	AICAR monophosphate	AKAP6 ARFGEF1 CD36 GLS SIK2 PYGB PYGL PYGM	2.18e-06	163	118	8	CID000000200
Drug	CV-araU	PYGB PYGL PYGM	2.68e-06	6	118	3	CID006441877
Drug	2-thiothymidine	PYGB PYGL PYGM	2.68e-06	6	118	3	CID003005944
Drug	Carbocyclic Bvdc	PYGB PYGL PYGM	2.68e-06	6	118	3	CID006438602
Drug	EdUMP	PYGB PYGL PYGM	2.68e-06	6	118	3	CID003085112
Drug	5'-deoxy-5'-chloroformycin	PYGB PYGL PYGM	2.68e-06	6	118	3	CID000126430
Drug	5-n-propylthioadenosine	PYGB PYGL PYGM	2.68e-06	6	118	3	CID000656428
Drug	AzddCyd	PYGB PYGL PYGM	2.68e-06	6	118	3	CID000451374
Drug	5-Ffdru	PYGB PYGL PYGM	2.68e-06	6	118	3	CID000065561
Drug	Carbocyclic Ivdu	PYGB PYGL PYGM	2.68e-06	6	118	3	CID006439191
Drug	DNPP	PYGB PYGL PYGM	2.68e-06	6	118	3	CID000067056
Drug	5-chloro-indole-2-carboxylic acid	PYGB PYGL PYGM	2.68e-06	6	118	3	CID000082693
Drug	NSC-97433	PYGB PYGL PYGM	2.68e-06	6	118	3	CID000001803
Drug	AR-L57	PYGB PYGL PYGM	2.68e-06	6	118	3	CID000156890
Drug	chloroethylclonidine	FOS ART1 PYGB PYGL PYGM	4.43e-06	47	118	5	CID000104973
Drug	prostaglandin F2	GPLD1 FOS CFTR BNC1 OTP ART1 CD36 PYGB PYGL PYGM	4.50e-06	306	118	10	CID000000160
Drug	alpha-(fluoromethyl)dehydroornithine	PYGB PYGL PYGM	4.68e-06	7	118	3	CID006439607
Drug	6-fluoropyridoxal	PYGB PYGL PYGM	4.68e-06	7	118	3	CID003080803
Drug	AC1L3372	PYGB PYGL PYGM	4.68e-06	7	118	3	CID000108025
Drug	1 Gpt	PYGB PYGL PYGM	4.68e-06	7	118	3	CID000101247
Drug	formycins	PYGB PYGL PYGM	4.68e-06	7	118	3	CID000512867
Drug	5'-methylthioinosine	PYGB PYGL PYGM	4.68e-06	7	118	3	CID000161214
Drug	hydantocidin	PYGB PYGL PYGM	4.68e-06	7	118	3	CID000125429
Drug	2',3'-dideoxy-3'-fluorocytidine	PYGB PYGL PYGM	4.68e-06	7	118	3	CID000356019
Drug	heptenitol	PYGB PYGL PYGM	4.68e-06	7	118	3	CID000188267
Drug	Promonta	PYGB PYGL PYGM	4.68e-06	7	118	3	CID000108494
Drug	AC1L9IMU	GLG1 PYGB PYGL PYGM	5.63e-06	23	118	4	CID000445825
Drug	Dietary Carbohydrates	GPLD1 KEAP1 GLG1 CD36 TCF25 PYGL PCK1 CNR1	6.53e-06	189	118	8	ctd:D004040
Drug	5-fluorouridylate	PYGB PYGL PYGM CDA	6.72e-06	24	118	4	CID000150856
Drug	6-methylpurine	PYGB PYGL PYGM	7.46e-06	8	118	3	CID005287547
Drug	Etafenone [inn]	PYGB PYGL PYGM	7.46e-06	8	118	3	CID000066659
Drug	AC1NUVX5	PYGB PYGL PYGM	7.46e-06	8	118	3	CID005461894
Drug	amorphin	PYGB PYGL PYGM	7.46e-06	8	118	3	CID000122792
Drug	Ioversol [87771-40-2]; Up 200; 5uM; HL60; HT_HG-U133A	LMF1 TAPBPL CFTR LAMP1 RGS9 SEMA6D SLC34A1 FRZB	8.84e-06	197	118	8	3026_UP
Drug	phorbol 12-myristate	SELL GPLD1 MAGI1 FOS AZU1 CFTR REL BNC1 ART1	8.97e-06	261	118	9	CID000107854
Drug	rimonabant	GPLD1 FOS COPG2 ERMP1 DDX27 CD36 GLS PCK1 CNR1	1.01e-05	265	118	9	ctd:C089032
Drug	alpha-maltosyl fluoride	PYGB PYGL PYGM	1.11e-05	9	118	3	CID000194237
Drug	nabumetone	SELL FOS UTRN	1.11e-05	9	118	3	ctd:C035605
Drug	6-benzyl-2-thiouracil	PYGB PYGL PYGM	1.11e-05	9	118	3	CID000685814
Drug	5'-methylthiotubercidin	PYGB PYGL PYGM	1.11e-05	9	118	3	CID000188350
Drug	5-Iodoribose 1-phosphate	PYGB PYGL PYGM	1.11e-05	9	118	3	CID003035973
Drug	5'-iodo-5'-deoxyadenosine	PYGB PYGL PYGM	1.11e-05	9	118	3	CID000107502
Drug	Phosphonoserine	CFTR PYGL PYGM	1.11e-05	9	118	3	DB04522
Drug	2-deoxyinosine	EIF5A PYGB PYGL PYGM CDA	1.49e-05	60	118	5	CID000000639
Drug	8-azidoadenosine 5'-monophosphate	PYGB PYGL PYGM	1.59e-05	10	118	3	CID000124726
Drug	6-methyluridine	PYGB PYGL PYGM	1.59e-05	10	118	3	CID000092887
Drug	UDP-pyridoxal	PYGB PYGL PYGM	1.59e-05	10	118	3	CID000126789
Drug	2,6-dihydroxypyridine	PYGB PYGL PYGM	1.59e-05	10	118	3	CID000069371
Disease	alkaline phosphatase measurement	SOX6 GPLD1 ERMP1 ACAD10 ATP6AP1L EIF5AL1 PHLDB1 CD36 EIF5A PYGB PYGL CDA UTRN LDLRAD4 PCK1	8.76e-06	1015	114	15	EFO_0004533
Disease	Clumsiness - motor delay	MED12L MED13	1.48e-05	2	114	2	C0520947
Disease	longevity	SOX6 NRDE2 WRN DDX27 GLS TCF25 CRYBG1 LDLRAD4	1.52e-05	284	114	8	EFO_0004300
Disease	Schizophrenia	DOCK4 MAGI1 ARHGAP32 RELN OFCC1 RGS9 ERVW-1 CFAP65 RTKN2 TET1 DIO3 PCK1 CNR1	3.78e-05	883	114	13	C0036341
Disease	Motor delay	MED12L MED13	4.43e-05	3	114	2	C1854301
Disease	Hodgkin Disease	RELN REL SOCS1	8.20e-05	22	114	3	C0019829
Disease	Delayed speech and language development	MED12L MED13	1.47e-04	5	114	2	C0454644
Disease	central nervous system cancer, glioma	AKAP6 LMF1 PHLDB1	1.91e-04	29	114	3	EFO_0000326, EFO_0005543
Disease	laryngeal carcinoma (is_marker_for)	KMT2C SOCS1	2.20e-04	6	114	2	DOID:2600 (is_marker_for)
Disease	age at diagnosis, substance-related disorder	BIRC6 SEMA6D	2.20e-04	6	114	2	EFO_0004918, MONDO_0002494
Disease	systolic blood pressure, body mass index	AKAP6 KEAP1 POLR1F	3.08e-04	34	114	3	EFO_0004340, EFO_0006335
Disease	multisite chronic pain	SOX6 SLC24A3 ITPR3 UTRN	5.13e-04	95	114	4	EFO_0010100
Disease	Adenoid Cystic Carcinoma	MAGI1 SLC24A3 KMT2C PYGB	6.23e-04	100	114	4	C0010606
Disease	response to fenofibrate	DOCK4 FAM135B CD36	9.64e-04	50	114	3	GO_1901557
Disease	reaction time measurement	AKAP6 SOX6 ATP6AP1L SEMA6D TET1 CHD6 CAMTA1 LDLRAD4 CNTN1	1.05e-03	658	114	9	EFO_0008393
Disease	Drug habituation	CFTR TIAM2 SEMA6D CNR1	1.05e-03	115	114	4	C0013170
Disease	Drug abuse	CFTR TIAM2 SEMA6D CNR1	1.05e-03	115	114	4	C0013146
Disease	Prescription Drug Abuse	CFTR TIAM2 SEMA6D CNR1	1.05e-03	115	114	4	C4316881
Disease	Substance-Related Disorders	CFTR TIAM2 SEMA6D CNR1	1.05e-03	115	114	4	C0236969
Disease	Drug Use Disorders	CFTR TIAM2 SEMA6D CNR1	1.05e-03	115	114	4	C0013222
Disease	Drug Dependence	CFTR TIAM2 SEMA6D CNR1	1.05e-03	115	114	4	C1510472
Disease	Substance Dependence	CFTR TIAM2 SEMA6D CNR1	1.05e-03	115	114	4	C0038580
Disease	Substance Use Disorders	CFTR TIAM2 SEMA6D CNR1	1.05e-03	115	114	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	CFTR TIAM2 SEMA6D CNR1	1.05e-03	115	114	4	C0029231
Disease	Substance abuse problem	CFTR TIAM2 SEMA6D CNR1	1.08e-03	116	114	4	C0740858
Disease	colitis (implicated_via_orthology)	SELL MUC2	1.12e-03	13	114	2	DOID:0060180 (implicated_via_orthology)
Disease	adult onset asthma	RANBP6 ERMP1 SIK2 MUC2	1.16e-03	118	114	4	EFO_1002011
Disease	age at menopause	BIRC6 ASH2L BNC1 TCF25 CHD6 LRRN4	1.16e-03	302	114	6	EFO_0004704
Disease	comparative body size at age 10, self-reported	AKAP6 MAGI1 RELN OFCC1 CADM1 SEMA6D CAMTA1	1.26e-03	420	114	7	EFO_0009819
Disease	cortical thickness	AKAP6 MAGI1 RELN GLIS3 ADGRV1 ATP6AP1L POLR1F BNC1 PHLDB1 GLS PYGB CAMTA1	1.26e-03	1113	114	12	EFO_0004840
Disease	cognitive function measurement	AKAP6 MAGI1 LMF1 WRN COPG2 ZDBF2 BIRC6 ATP6AP1L FAM135B SEMA6D MED12L CRYBG1 MUC2 LDLRAD4	1.28e-03	1434	114	14	EFO_0008354
Disease	testosterone measurement	SOX6 DOCK4 MAGI1 NRDE2 GLIS3 SLC24A3 BIRC6 C3P1 THOP1 SEMA6D SLC34A1 MYO15A UTRN	1.31e-03	1275	114	13	EFO_0004908
Disease	hair color	SOX6 ERMP1 ADGRV1 BNC1 SEMA6D TCF25	1.34e-03	311	114	6	EFO_0003924
Disease	obesity (implicated_via_orthology)	ITPR3 CD36 MED12L MED13 CNR1	1.51e-03	215	114	5	DOID:9970 (implicated_via_orthology)
Disease	smoking behaviour measurement	SOX6 SLC24A3 CDH22 SEMA6D CAMTA1	1.74e-03	222	114	5	EFO_0005671
Disease	cystic fibrosis (is_marker_for)	CFTR MUC5B MUC2	1.80e-03	62	114	3	DOID:1485 (is_marker_for)
Disease	cyclic adenosine monophosphate measurement	OFCC1 CD36	1.94e-03	17	114	2	EFO_0010473
Disease	Huntington Disease	RELN CNR1	1.94e-03	17	114	2	C0020179
Disease	Alzheimer disease, gastroesophageal reflux disease	AKAP6 PTCHD4 FAM135B PYGL CAMTA1	1.96e-03	228	114	5	EFO_0003948, MONDO_0004975
Disease	red blood cell density measurement	SOX6 OFCC1 NKX2-3 ACAD10 ADGRV1 SLC34A1 ARID2 CD36 CAMTA1 MYO15A	2.21e-03	880	114	10	EFO_0007978
Disease	unipolar depression	SOX6 OFCC1 MUC5B FAM135B POLR1F EIF5AL1 SEMA6D CD36 EIF5A CHD6 CAMTA1 CNTN1	2.46e-03	1206	114	12	EFO_0003761
Disease	hair colour measurement	SOX6 RANBP6 ADGRV1 BNC1 SEMA6D MED12L TCF25 CREB3L3	2.71e-03	615	114	8	EFO_0007822
Disease	glucagon measurement	TIAM2 BNC1 CDH22 TRAV23DV6	3.05e-03	154	114	4	EFO_0008463
Disease	PR interval	AKAP6 DOCK4 MAGI1 ARID2 CHD6 CAMTA1 CNR1	3.16e-03	495	114	7	EFO_0004462
Disease	glioma	LMF1 PHLDB1	3.25e-03	22	114	2	EFO_0005543
Disease	Alzheimer's disease (is_marker_for)	SELL RELN CFTR APBB1 CD36	3.27e-03	257	114	5	DOID:10652 (is_marker_for)
Disease	nicotine dependence	SOX6 GLIS3 POLR1F	3.46e-03	78	114	3	EFO_0003768
Disease	Attention deficit hyperactivity disorder	MED13 CNR1	3.86e-03	24	114	2	C1263846

Protein segments in the cluster

Peptide	Gene	Start	Entry
SEDGARAPFTQAEMC	CAMTA1	806	Q9Y6Y1
MSANSDIGLGDSICF	AGAP11	211	Q8TF27
LQPDFSSKLMGCDSF	CFTR	636	P13569
HQPASSGDDRAMCFT	BIRC6	316	Q9NR09
ASAACSMDPIDSFEL	CREB3L3	11	Q68CJ9
ACNAAFPDTSMEAIR	ARFGEF1	1331	Q9Y6D6
MCFDNQVSLGFSPSQ	A2ML1	556	A8K2U0
ASPQLAEESCSAMAA	ADGRV1	5961	Q8WXG9
ALSNRGMAFPCLEDS	BNC1	686	Q01954
ISDPNNAGCSATMVA	ARID2	1541	Q68CP9
NAGCSATMVAVPAGA	ARID2	1546	Q68CP9
CFAMTEPQVASSDAT	ACAD10	791	Q6JQN1
PNAASLSEAVQAACM	APBB1	641	O00213
NAMPFSTSDVDNDGC	ANGPTL5	296	Q86XS5
VLASGSGFCDNMLAD	DDX27	21	Q96GQ7
NSPGASDDAVSCSVM	ERMP1	211	Q7Z2K6
ADTFGIDTSSCLPFM	ASH2L	126	Q9UBL3
VAENSAGMACAAASL	IGDCC4	406	Q8TDY8
STGCAAPMVYLDCSN	MUC5B	791	Q9HC84
APMVYLDCSNSSAGT	MUC5B	796	Q9HC84
SDMESFKAANPGCSL	RAB3GAP1	681	Q15042
SMANSGPSTNGCQFF	PPIH	111	O43447
AAAFPSACGKTNLAM	PCK1	281	P35558
QFSSNDAIMSGCLPS	RGS9	256	O75916
EALCMLAQSSPSFAE	INTS4	396	Q96HW7
SASVMAATLANGGFC	GLS	426	O94925
GTAPAFDSTTANMNL	ITPR3	1011	Q14573
SAAEAGAMTLCITNP	SLC25A32	126	Q9H2D1
MAANVSGAKSCPANF	P2RY11	1	Q96G91
EGSFCASSNSPMHSQ	KMT2C	2331	Q8NEZ4
MSPVQLAFSDFLSCA	MED12L	341	Q86YW9
QNFFSLACSLMGPSR	M1AP	46	Q8TC57
EAGTTFAGNACVAMP	MAGI1	1021	Q96QZ7
SFSSMGSPVNAQDFC	FOS	36	P01100
GGPASMATVNQCFFT	LRRK1	701	Q38SD2
SMALDVGCFNGDQFS	MYO15A	2221	Q9UKN7
APGCALVLDTMANSS	DIO3	236	P55073
PAINDSSAAMSACST	CFAP65	101	Q6ZU64
DAGASSTYPMQCSAL	EIF5A2	11	Q9GZV4
SCFMPGSSLECASLQ	MUC2	4721	Q02817
FENAMRSDSGSQCPL	NRDE2	1076	Q9H7Z3
QCLMSSSTPECAAGF	COIL	326	P38432
GTMDCTHPLGNFSFS	SELL	206	P14151
DAINSGATPCLENAM	GBP7	301	Q8N8V2
DAGASATFPMQCSAL	EIF5A	11	P63241
LPNSGAAATSAAMAA	RBM4B	276	Q9BQ04
FISDSGAAAAQCPMA	ARHGAP32	1361	A7KAX9
FLAAGTSVPDCMASL	SLC24A3	516	Q9HC58
NETFCAATPSAMIFG	RELN	1266	P78509
PNTMLFASEACVGSK	GBA	371	P04062
CSLDMLSSAFQLAGG	SLC34A1	116	Q06495
AFNMSSPDLSACQTA	OFCC1	41	Q8IZS5
SANGSFSCDMAVPKN	PATZ1	581	Q9HBE1
MASVVLPSGSQCAAA	CADM1	1	Q9BY67
NETSEFMPQGAVFSC	GLG1	581	Q92896
EMACHGSSSFLPAAN	CEFIP	226	Q711Q0
DAGASATFPMQCSAL	EIF5AL1	11	Q6IS14
SLGIQEFSACMQASP	DOCK4	1586	Q8N1I0
DSFASPSGCGMLLNQ	C3P1	326	Q6ZMU1
NPGNESGFVDMCSLS	CHD6	1816	Q8TD26
SHCDMINGTDAASFP	CD36	241	P16671
SFEDCLVPTSMGQAS	GLIS3	701	Q8NEA6
NATMQCAASFDPALD	CNTN1	521	Q12860
HAFRSMFPSCEGTAQ	CNR1	406	P21554
DDDPTAVAGSFSCTM	COPG2	711	Q9UBF2
RNNLAGIASDFPSMC	MARF1	166	Q9Y4F3
GIASDFPSMCLESNL	MARF1	171	Q9Y4F3
MALASAAPGSIFCKQ	DSC1	1	Q08554
GNTDSSALDCYNPMT	KEAP1	386	Q14145
GNGTACIMANFSAAF	LAMP1	36	P11279
TEAAAATAGIATFCM	SERPINB1	331	P30740
CNTTAFVMAASLSPG	CDH22	611	Q9UJ99
SNLPNCANSDTDFMG	CRYBG1	971	Q9Y4K1
QSGSPCIMDDTAFNR	FAM135B	956	Q49AJ0
ADTIAGDPMCSFNMT	HDAC8	266	Q9BY41
FVMTAASCFQSQNPG	AZU1	61	P20160
HSAPCMLAAAEGTQF	NKX2-3	41	Q8TAU0
AFDVEAMNFPSSGLC	ATP4A	581	P20648
LSRAADTMCAPAAGS	LRRN4	331	Q8WUT4
AMAQSLSQCSLAAGP	OTP	231	Q5XKR4
PACMAEDAFAGFLNQ	RTKN2	281	Q8IZC4
SCSALMSQPSAPDFV	UTRN	861	P46939
NGSSESMCFLSFLVP	ERVW-1	281	Q9UQF0
SSASLDCGFSMAPGL	TAPBPL	206	Q9BX59
MAAAANSGSSLPLFD	PPP1R8	1	Q12972
ACDTLMSQSFGSPNK	SLC47A2	91	Q86VL8
MDSAACAAAATPVPA	RIPPLY1	1	Q0D2K3
SFSFMGCLQISDGAN	PTCHD4	476	Q6ZW05
ELNTFSFCGNPISMA	PRAMEF25	381	A6NGN4
FPASGCQAEAAFMEE	SIK2	401	Q9H0K1
GESLPARFFSCMQSD	SIRT2	236	Q8IXJ6
ELNAFSFCGNPISMA	PRAMEF27	381	A3QJZ7
MSNIPACFLGSAQSE	WRN	611	Q14191
MSASFVPNGASLEDC	MED13	1	Q9UHV7
AACTTLGQMATDFAP	RANBP6	426	O60518
CFFALSVKMASGPTS	SOCS1	111	O15524
AAAGAASMACAPPSA	DZIP1	36	Q86YF9
CAPAMADGSFSLAGH	RAX	6	Q9Y2V3
ATSPFACAADGEDAM	SOX6	6	P35712
FQNPESLTCNGFTMA	TET1	91	Q8NFU7
AMPLQATACSSEFSD	AKAP6	2186	Q13023
AIASDMQDDFISPCG	CDA	86	P32320
SVSPAMCAVGSEDGF	WDR90	626	Q96KV7
SSRLDSAMAVCFGPA	WDR90	881	Q96KV7
MTFNSFEGSKTCVPA	XIAP	1	P98170
NSMDQSSAPRCALFA	TIAM2	556	Q8IVF5
AACFLDSMATLGLAA	PYGM	141	P11217
ADGADFPMDSSNGNC	FRZB	156	Q92765
FPMDSSNGNCRGASS	FRZB	161	Q92765
SIADNSPLFGLDCEM	REXO5	221	Q96IC2
SFMLENGTSDCNLPE	GPLD1	266	P80108
AACFLDSMATLGLAA	PYGB	141	P11216
SCSEMNLDSGFLGQS	ZDBF2	1156	Q9HCK1
DFSCADNSMINESGP	REL	566	Q04864
MAAGCSEAPRPAAAS	POLR1F	1	Q3B726
ACSPDNMSSASGLDM	PHLDB1	1131	Q86UU1
SDNCGSMVPSFADIL	MTFR2	66	Q6P444
RCAAFPMASSFSDCN	ZNF544	331	Q6NX49
GTFPAACSATQIAEM	STRCP1	1466	A6NGW2
MDSQPGDSATYFCAA	TRAV23DV6	106	A0A075B6W5
NSIPGSAVCAFSMDD	SEMA6D	321	Q8NFY4
ACAGDMADAASPCSV	THOP1	6	P52888
AACFLDSMATLGLAA	PYGL	141	P06737
CASSFSPAFLIGLAM	ATP6AP1L	141	Q52LC2
MECAFHPLFSLTSGA	TCF25	316	Q9BQ70
MPEAGFQATNAFTEC	LDLRAD4	1	O15165
MVPSLACFDDATLGF	LMF1	316	Q96S06
AGCAAAMTAALPDLN	ART1	51	P52961