Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	olfactory receptor activity	OR3A2 OR51E1 OR4M2 OR4A8 OR4S2 OR4Q2 OR1Q1 OR10W1 OR4M1 OR52E1 OR4C46 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 OR52M1 OR4X1 OR7A10 OR52B6 OR6K6 OR4M2B	1.44e-22	431	56	22	GO:0004984
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR3A2 GABRP OR51E1 OR4M2 OR4A8 OR4S2 OR4Q2 OR1Q1 OR10W1 OR4M1 OR52E1 TMEM63B OR4C46 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 HTR3B OR52M1 OR4X1 OR7A10 OR52B6 OR6K6 OR4M2B GABRA5	2.93e-16	1353	56	26	GO:0004888
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR3A2 OR51E1 OR4M2 OR4A8 OR4S2 OR4Q2 OR1Q1 OR10W1 OR4M1 OR52E1 OR4C46 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 OR52M1 OR4X1 OR7A10 OR52B6 OR6K6 OR4M2B	6.50e-16	884	56	22	GO:0004930
GeneOntologyMolecularFunction	transmembrane transporter activity	GABRP AQP11 TMEM63B ABCB11 SLCO4A1 SV2C CACNA1I SLC35E4 HTR3B PKD1L2 SLC16A7 UNC80 RYR1 RYR2 GABRA5	5.62e-07	1180	56	15	GO:0022857
GeneOntologyMolecularFunction	transporter activity	GABRP AQP11 TMEM63B ABCB11 SLCO4A1 SV2C CACNA1I SLC35E4 HTR3B PKD1L2 SLC16A7 UNC80 RYR1 RYR2 GABRA5	1.71e-06	1289	56	15	GO:0005215
GeneOntologyMolecularFunction	channel activity	GABRP AQP11 TMEM63B CACNA1I HTR3B PKD1L2 UNC80 RYR1 RYR2 GABRA5	1.74e-06	525	56	10	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	GABRP AQP11 TMEM63B CACNA1I HTR3B PKD1L2 UNC80 RYR1 RYR2 GABRA5	1.77e-06	526	56	10	GO:0022803
GeneOntologyMolecularFunction	monoatomic ion channel activity	GABRP TMEM63B CACNA1I HTR3B PKD1L2 UNC80 RYR1 RYR2 GABRA5	4.81e-06	459	56	9	GO:0005216
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	GABRP TMEM63B HTR3B RYR1 RYR2 GABRA5	1.64e-05	193	56	6	GO:0015276
GeneOntologyMolecularFunction	ligand-gated channel activity	GABRP TMEM63B HTR3B RYR1 RYR2 GABRA5	1.84e-05	197	56	6	GO:0022834
GeneOntologyMolecularFunction	gated channel activity	GABRP TMEM63B CACNA1I HTR3B RYR1 RYR2 GABRA5	3.95e-05	334	56	7	GO:0022836
GeneOntologyMolecularFunction	ryanodine-sensitive calcium-release channel activity	RYR1 RYR2	4.62e-05	4	56	2	GO:0005219
GeneOntologyMolecularFunction	monoatomic cation channel activity	TMEM63B CACNA1I HTR3B PKD1L2 UNC80 RYR1 RYR2	4.67e-05	343	56	7	GO:0005261
GeneOntologyMolecularFunction	calcium-induced calcium release activity	RYR1 RYR2	1.15e-04	6	56	2	GO:0048763
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	GABRP TMEM63B CACNA1I HTR3B PKD1L2 UNC80 RYR1 RYR2 GABRA5	3.33e-04	793	56	9	GO:0015075
GeneOntologyMolecularFunction	calcium channel activity	CACNA1I PKD1L2 RYR1 RYR2	4.71e-04	129	56	4	GO:0005262
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	TMEM63B HTR3B RYR1 RYR2	6.41e-04	140	56	4	GO:0099094
GeneOntologyMolecularFunction	transmitter-gated channel activity	GABRP HTR3B GABRA5	8.07e-04	65	56	3	GO:0022835
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity	GABRP HTR3B GABRA5	8.07e-04	65	56	3	GO:0022824
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CACNA1I PKD1L2 RYR1 RYR2	8.50e-04	151	56	4	GO:0015085
GeneOntologyMolecularFunction	organic hydroxy compound transmembrane transporter activity	AQP11 ABCB11 SLC16A7	1.00e-03	70	56	3	GO:1901618
GeneOntologyMolecularFunction	GABA-gated chloride ion channel activity	GABRP GABRA5	1.15e-03	18	56	2	GO:0022851
GeneOntologyMolecularFunction	intracellularly gated calcium channel activity	RYR1 RYR2	1.15e-03	18	56	2	GO:0015278
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	GABRP AQP11 TMEM63B CACNA1I PKD1L2 RYR1 RYR2 GABRA5	1.18e-03	758	56	8	GO:0015318
GeneOntologyMolecularFunction	GABA-A receptor activity	GABRP GABRA5	1.28e-03	19	56	2	GO:0004890
GeneOntologyMolecularFunction	extracellular ligand-gated monoatomic ion channel activity	GABRP HTR3B GABRA5	1.32e-03	77	56	3	GO:0005230
GeneOntologyMolecularFunction	GABA receptor activity	GABRP GABRA5	1.72e-03	22	56	2	GO:0016917
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	TMEM63B CACNA1I HTR3B PKD1L2 UNC80 RYR1 RYR2	2.46e-03	664	56	7	GO:0008324
GeneOntologyMolecularFunction	mannosyltransferase activity	PIGV ALG1	2.79e-03	28	56	2	GO:0000030
GeneOntologyMolecularFunction	neurotransmitter receptor activity	GABRP HTR3B GABRA5	2.79e-03	100	56	3	GO:0030594
GeneOntologyMolecularFunction	ligand-gated calcium channel activity	RYR1 RYR2	3.41e-03	31	56	2	GO:0099604
GeneOntologyMolecularFunction	intracellularly ligand-gated monoatomic ion channel activity	RYR1 RYR2	3.86e-03	33	56	2	GO:0005217
GeneOntologyMolecularFunction	3'-5'-RNA exonuclease activity	XRN2 PAN2	4.83e-03	37	56	2	GO:0000175
GeneOntologyMolecularFunction	odorant binding	OR10W1 OR10K2 OR6K6	5.45e-03	127	56	3	GO:0005549
GeneOntologyMolecularFunction	RNA exonuclease activity, producing 5'-phosphomonoesters	XRN2 PAN2	5.63e-03	40	56	2	GO:0016896
GeneOntologyMolecularFunction	carbohydrate transmembrane transporter activity	AQP11 ABCB11	6.19e-03	42	56	2	GO:0015144
GeneOntologyMolecularFunction	RNA exonuclease activity	XRN2 PAN2	7.08e-03	45	56	2	GO:0004532
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACNA1I RYR1	7.39e-03	46	56	2	GO:0005245
GeneOntologyMolecularFunction	ligand-gated monoatomic anion channel activity	GABRP GABRA5	8.68e-03	50	56	2	GO:0099095
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	HTR3B GABRA5	1.12e-02	57	56	2	GO:1904315
GeneOntologyMolecularFunction	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	HTR3B GABRA5	1.23e-02	60	56	2	GO:0099529
GeneOntologyMolecularFunction	3'-5' exonuclease activity	XRN2 PAN2	1.27e-02	61	56	2	GO:0008408
GeneOntologyMolecularFunction	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	XRN2 PAN2	1.31e-02	62	56	2	GO:0016796
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR3A2 OR51E1 OR4M2 OR4A8 OR4S2 OR4Q2 OR1Q1 OR10W1 OR4M1 OR52E1 OR4C46 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 OR52M1 OR4X1 OR7A10 OR52B6 OR6K6 OR4M2B	4.69e-23	432	55	22	GO:0050911
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR3A2 OR51E1 OR4M2 OR4A8 OR4S2 OR4Q2 OR1Q1 OR10W1 OR4M1 OR52E1 OR4C46 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 OR52M1 OR4X1 OR7A10 OR52B6 OR6K6 OR4M2B RYR2	1.12e-22	524	55	23	GO:0009593
GeneOntologyBiologicalProcess	sensory perception of smell	OR3A2 OR51E1 OR4M2 OR4A8 OR4S2 OR4Q2 OR1Q1 OR10W1 OR4M1 OR52E1 OR4C46 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 OR52M1 OR4X1 OR7A10 OR52B6 OR6K6 OR4M2B	2.34e-22	465	55	22	GO:0007608
GeneOntologyBiologicalProcess	detection of stimulus	OR3A2 OR51E1 OR4M2 OR4A8 OR4S2 OR4Q2 OR1Q1 OR10W1 NAIP OR4M1 OR52E1 OR4C46 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 PKD1L2 OR52M1 OR4X1 OR7A10 OR52B6 OR6K6 OR4M2B RYR2	3.06e-22	722	55	25	GO:0051606
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR3A2 OR51E1 OR4M2 OR4A8 OR4S2 OR4Q2 OR1Q1 OR10W1 OR4M1 OR52E1 OR4C46 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 OR52M1 OR4X1 OR7A10 OR52B6 OR6K6 OR4M2B	5.85e-22	485	55	22	GO:0050907
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR3A2 OR51E1 OR4M2 OR4A8 OR4S2 OR4Q2 OR1Q1 OR10W1 OR4M1 OR52E1 OR4C46 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 OR52M1 OR4X1 OR7A10 OR52B6 OR6K6 OR4M2B	7.91e-21	547	55	22	GO:0007606
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR3A2 OR51E1 OR4M2 OR4A8 OR4S2 OR4Q2 OR1Q1 OR10W1 OR4M1 OR52E1 OR4C46 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 OR52M1 OR4X1 OR7A10 OR52B6 OR6K6 OR4M2B	3.01e-20	582	55	22	GO:0050906
GeneOntologyBiologicalProcess	sensory perception	OR3A2 OR51E1 OR4M2 OR4A8 OR4S2 OR4Q2 OR1Q1 OR10W1 OR4M1 OR52E1 TMEM63B OR4C46 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 OR52M1 OR4X1 OR7A10 OR52B6 OR6K6 OR4M2B	8.74e-16	1072	55	23	GO:0007600
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR3A2 OR51E1 OR4M2 ADCY4 OR4A8 OR4S2 OR4Q2 OR1Q1 OR10W1 OR4M1 OR52E1 OR4C46 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 OR52M1 OR4X1 OR7A10 OR52B6 OR6K6 OR4M2B	2.37e-13	1395	55	23	GO:0007186
GeneOntologyBiologicalProcess	positive regulation of response to food	OR4M2 OR4M1	1.45e-04	7	55	2	GO:0032097
GeneOntologyBiologicalProcess	positive regulation of appetite	OR4M2 OR4M1	1.45e-04	7	55	2	GO:0032100
GeneOntologyBiologicalProcess	positive regulation of response to nutrient levels	OR4M2 OR4M1	1.93e-04	8	55	2	GO:0032109
GeneOntologyBiologicalProcess	monoatomic ion transport	GABRP DPP10 AQP11 TMEM63B SLCO4A1 CACNA1I HTR3B PKD1L2 UNC80 RYR1 RYR2 GABRA5	2.19e-04	1374	55	12	GO:0006811
GeneOntologyBiologicalProcess	cellular response to caffeine	RYR1 RYR2	3.78e-04	11	55	2	GO:0071313
GeneOntologyBiologicalProcess	cellular response to purine-containing compound	RYR1 RYR2	6.22e-04	14	55	2	GO:0071415
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	GABRP DPP10 TMEM63B CACNA1I HTR3B PKD1L2 UNC80 RYR1 RYR2 GABRA5	6.48e-04	1115	55	10	GO:0034220
GeneOntologyCellularComponent	monoatomic ion channel complex	GABRP DPP10 CACNA1I HTR3B UNC80 RYR1 RYR2 GABRA5	7.07e-06	378	56	8	GO:0034702
GeneOntologyCellularComponent	cation channel complex	DPP10 CACNA1I HTR3B UNC80 RYR1 RYR2	3.84e-05	235	56	6	GO:0034703
GeneOntologyCellularComponent	transmembrane transporter complex	GABRP DPP10 CACNA1I HTR3B UNC80 RYR1 RYR2 GABRA5	7.19e-05	523	56	8	GO:1902495
GeneOntologyCellularComponent	transporter complex	GABRP DPP10 CACNA1I HTR3B UNC80 RYR1 RYR2 GABRA5	1.02e-04	550	56	8	GO:1990351
GeneOntologyCellularComponent	junctional sarcoplasmic reticulum membrane	RYR1 RYR2	3.13e-04	10	56	2	GO:0014701
GeneOntologyCellularComponent	calcium channel complex	CACNA1I RYR1 RYR2	9.92e-04	73	56	3	GO:0034704
GeneOntologyCellularComponent	GABA-A receptor complex	GABRP GABRA5	1.17e-03	19	56	2	GO:1902711
GeneOntologyCellularComponent	GABA receptor complex	GABRP GABRA5	1.43e-03	21	56	2	GO:1902710
GeneOntologyCellularComponent	endoplasmic reticulum membrane	AQP11 CH25H TMEM214 UNC93B1 PIGV OR7A10 OR6K6 ALG1 RYR1 RYR2	2.08e-03	1293	56	10	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	AQP11 CH25H TMEM214 UNC93B1 PIGV OR7A10 OR6K6 ALG1 RYR1 RYR2	2.15e-03	1299	56	10	GO:0098827
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	AQP11 CH25H TMEM214 UNC93B1 PIGV OR7A10 OR6K6 ALG1 RYR1 RYR2	2.51e-03	1327	56	10	GO:0042175
GeneOntologyCellularComponent	sodium channel complex	CACNA1I UNC80	2.73e-03	29	56	2	GO:0034706
Domain	Olfact_rcpt	OR3A2 OR51E1 OR4M2 OR4S2 OR1Q1 OR10W1 OR4M1 OR4C46 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 OR52M1 OR4X1 OR7A10 OR52B6 OR6K6	9.86e-18	393	52	18	IPR000725
Domain	GPCR_Rhodpsn_7TM	OR3A2 OR51E1 OR4M2 OR4S2 OR1Q1 OR10W1 OR4M1 OR4C46 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 OR52M1 OR4X1 OR7A10 OR52B6 OR6K6	1.05e-13	670	52	18	IPR017452
Domain	7tm_1	OR3A2 OR51E1 OR4M2 OR4S2 OR1Q1 OR10W1 OR4M1 OR4C46 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 OR52M1 OR4X1 OR7A10 OR52B6 OR6K6	1.26e-13	677	52	18	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR3A2 OR51E1 OR4M2 OR4S2 OR1Q1 OR10W1 OR4M1 OR4C46 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 OR52M1 OR4X1 OR7A10 OR52B6 OR6K6	1.54e-13	685	52	18	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR3A2 OR51E1 OR4M2 OR4S2 OR1Q1 OR10W1 OR4M1 OR4C46 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 OR52M1 OR4X1 OR7A10 OR52B6 OR6K6	1.78e-13	691	52	18	PS50262
Domain	GPCR_Rhodpsn	OR3A2 OR51E1 OR4M2 OR4S2 OR1Q1 OR10W1 OR4M1 OR4C46 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 OR52M1 OR4X1 OR7A10 OR52B6 OR6K6	1.83e-13	692	52	18	IPR000276
Domain	RyR	RYR1 RYR2	2.28e-05	3	52	2	PF02026
Domain	Ryanodine_rcpt	RYR1 RYR2	2.28e-05	3	52	2	IPR003032
Domain	RR_TM4-6	RYR1 RYR2	2.28e-05	3	52	2	PF06459
Domain	Ryanrecept_TM4-6	RYR1 RYR2	2.28e-05	3	52	2	IPR009460
Domain	Ryan_recept	RYR1 RYR2	2.28e-05	3	52	2	IPR013333
Domain	RIH_assoc	RYR1 RYR2	1.13e-04	6	52	2	PF08454
Domain	RIH_assoc-dom	RYR1 RYR2	1.13e-04	6	52	2	IPR013662
Domain	RYDR_ITPR	RYR1 RYR2	1.13e-04	6	52	2	PF01365
Domain	RIH_dom	RYR1 RYR2	1.13e-04	6	52	2	IPR000699
Domain	Ins145_P3_rcpt	RYR1 RYR2	1.13e-04	6	52	2	IPR014821
Domain	Ryanodine_recept-rel	RYR1 RYR2	1.13e-04	6	52	2	IPR015925
Domain	Ins145_P3_rec	RYR1 RYR2	1.13e-04	6	52	2	PF08709
Domain	-	RYR1 RYR2	1.13e-04	6	52	2	1.25.10.30
Domain	Neur_chan_memb	GABRP HTR3B GABRA5	2.84e-04	46	52	3	PF02932
Domain	Neur_chan_LBD	GABRP HTR3B GABRA5	3.03e-04	47	52	3	PF02931
Domain	Neur_channel	GABRP HTR3B GABRA5	3.03e-04	47	52	3	IPR006201
Domain	Neur_chan_lig-bd	GABRP HTR3B GABRA5	3.03e-04	47	52	3	IPR006202
Domain	NEUROTR_ION_CHANNEL	GABRP HTR3B GABRA5	3.03e-04	47	52	3	PS00236
Domain	Neurotrans-gated_channel_TM	GABRP HTR3B GABRA5	3.03e-04	47	52	3	IPR006029
Domain	-	GABRP HTR3B GABRA5	3.03e-04	47	52	3	2.70.170.10
Domain	MIR	RYR1 RYR2	3.37e-04	10	52	2	PS50919
Domain	MIR	RYR1 RYR2	3.37e-04	10	52	2	PF02815
Domain	MIR	RYR1 RYR2	3.37e-04	10	52	2	SM00472
Domain	MIR_motif	RYR1 RYR2	3.37e-04	10	52	2	IPR016093
Domain	GABAA/Glycine_rcpt	GABRP GABRA5	1.85e-03	23	52	2	IPR006028
Domain	MFS	SLCO4A1 SV2C SLC16A7	3.38e-03	108	52	3	PS50850
Domain	Ion_trans_dom	CACNA1I RYR1 RYR2	3.94e-03	114	52	3	IPR005821
Domain	Ion_trans	CACNA1I RYR1 RYR2	3.94e-03	114	52	3	PF00520
Domain	EF-hand_8	RYR1 RYR2	4.03e-03	34	52	2	PF13833
Domain	MFS_dom	SLCO4A1 SV2C SLC16A7	6.18e-03	134	52	3	IPR020846
Domain	Neurotransmitter_ion_chnl_CS	GABRP GABRA5	6.97e-03	45	52	2	IPR018000
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR3A2 OR51E1 OR4M2 OR4A8 OR4S2 OR4Q2 OR1Q1 OR10W1 OR4M1 OR52E1 OR4C46 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 OR52M1 OR4X1 OR7A10 OR52B6 OR6K6	2.93e-20	417	47	21	M4072
Pathway	REACTOME_SENSORY_PERCEPTION	OR3A2 OR51E1 OR4M2 OR4A8 OR4S2 OR4Q2 OR1Q1 OR10W1 OR4M1 OR52E1 OR4C46 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 OR52M1 OR4X1 OR7A10 OR52B6 OR6K6	1.66e-16	636	47	21	M41834
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR3A2 OR51E1 OR4M2 OR4S2 OR1Q1 OR4M1 OR4C46 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 OR52M1 OR4X1 OR7A10 OR52B6 OR6K6	2.84e-15	389	47	17	M14091
Pathway	KEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY	RYR1 RYR2	5.87e-04	11	47	2	M47958
Pubmed	The human olfactory receptor gene family.	OR3A2 OR51E1 OR4M2 OR4A8 OR4S2 OR4Q2 OR1Q1 OR10W1 OR4M1 OR56A3 OR10K2 OR3A3 OR2J3 OR4D11 OR52M1 OR4X1 OR7A10 OR52B6 OR6K6	8.06e-21	541	56	19	14983052
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR51E1 OR4M2 OR4A8 OR4S2 OR1Q1 OR10W1 OR4M1 OR4C46 OR56A3 OR10K2 OR2J3 OR4D11 OR52M1 OR7A10 OR6K6	6.74e-18	343	56	15	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR51E1 OR4M2 OR4A8 OR4S2 OR1Q1 OR10W1 OR4M1 OR4C46 OR56A3 OR10K2 OR2J3 OR4D11 OR52M1 OR7A10 OR6K6	7.68e-18	346	56	15	14611657
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR51E1 OR4M2 OR4A8 OR4S2 OR1Q1 OR10W1 OR4M1 OR4C46 OR56A3 OR10K2 OR2J3 OR4D11 OR52M1 OR7A10	2.23e-16	340	56	14	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR51E1 OR4M2 OR4A8 OR4S2 OR1Q1 OR10W1 OR4M1 OR4C46 OR56A3 OR10K2 OR2J3 OR4D11 OR52M1 OR7A10	2.23e-16	340	56	14	11802173
Pubmed	Population differences in the human functional olfactory repertoire.	OR4A8 OR4S2 OR3A3 OR52M1	1.97e-09	11	56	4	12644552
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR4S2 OR4Q2 OR1Q1 OR3A3 OR2J3 OR4D11 OR7A10	6.36e-08	219	56	7	12213199
Pubmed	Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling.	RYR1 RYR2	2.55e-06	2	56	2	30542613
Pubmed	Ryanodine receptors are expressed and functionally active in mouse spermatogenic cells and their inhibition interferes with spermatogonial differentiation.	RYR1 RYR2	2.55e-06	2	56	2	15280431
Pubmed	Expression of the ryanodine receptor isoforms in immune cells.	RYR1 RYR2	2.55e-06	2	56	2	11673493
Pubmed	B-lymphocytes from malignant hyperthermia-susceptible patients have an increased sensitivity to skeletal muscle ryanodine receptor activators.	RYR1 RYR2	2.55e-06	2	56	2	11673462
Pubmed	Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+.	RYR1 RYR2	2.55e-06	2	56	2	17259277
Pubmed	Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.	RYR1 RYR2	2.55e-06	2	56	2	25370123
Pubmed	Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.	RYR1 RYR2	2.55e-06	2	56	2	15033925
Pubmed	Ryanodine receptor oligomeric interaction: identification of a putative binding region.	RYR1 RYR2	2.55e-06	2	56	2	14722100
Pubmed	Structural and functional interactions within ryanodine receptor.	RYR1 RYR2	2.55e-06	2	56	2	26009179
Pubmed	Thermodynamics of calmodulin binding to cardiac and skeletal muscle ryanodine receptor ion channels.	RYR1 RYR2	2.55e-06	2	56	2	18618700
Pubmed	Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies-Present State, Challenges, and Perspectives.	RYR1 RYR2	2.55e-06	2	56	2	32899693
Pubmed	Odorant and vomeronasal receptor genes in two mouse genome assemblies.	OR4A8 OR56A3 OR7A10 OR6K6	6.38e-06	74	56	4	15081110
Pubmed	Dopamine D1 receptor signaling system regulates ryanodine receptor expression in ethanol physical dependence.	RYR1 RYR2	7.63e-06	3	56	2	23278119
Pubmed	The Asprosin-OLFR734 hormonal signaling axis modulates male fertility.	OR4M2 OR4M1	7.63e-06	3	56	2	31798959
Pubmed	Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.	RYR1 RYR2	7.63e-06	3	56	2	9242641
Pubmed	Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.	RYR1 RYR2	7.63e-06	3	56	2	18403125
Pubmed	Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.	RYR1 RYR2	7.63e-06	3	56	2	22948152
Pubmed	Direct association of the reticulon protein RTN1A with the ryanodine receptor 2 in neurons.	RYR1 RYR2	7.63e-06	3	56	2	23454728
Pubmed	Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.	RYR1 RYR2	7.63e-06	3	56	2	10788707
Pubmed	Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.	RYR1 RYR2	7.63e-06	3	56	2	18434746
Pubmed	Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.	RYR1 RYR2	7.63e-06	3	56	2	25239916
Pubmed	Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.	RYR1 RYR2	7.63e-06	3	56	2	7621815
Pubmed	SPRY domains in ryanodine receptors (Ca(2+)-release channels).	RYR1 RYR2	7.63e-06	3	56	2	9204703
Pubmed	A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.	RYR1 RYR2	7.63e-06	3	56	2	18643873
Pubmed	Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).	RYR1 RYR2	7.63e-06	3	56	2	11159936
Pubmed	The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.	RYR1 RYR2	7.63e-06	3	56	2	7876312
Pubmed	Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.	RYR1 RYR2	7.63e-06	3	56	2	21881589
Pubmed	Intracellular calcium release channel expression during embryogenesis.	RYR1 RYR2	7.63e-06	3	56	2	9986730
Pubmed	Dendritic differentiation of cerebellar Purkinje cells is promoted by ryanodine receptors expressed by Purkinje and granule cells.	RYR1 RYR2	7.63e-06	3	56	2	24123915
Pubmed	The Asprosin-OLFR734 module regulates appetitive behaviors.	OR4M2 OR4M1	7.63e-06	3	56	2	32337066
Pubmed	Molecular identification of the ryanodine receptor pore-forming segment.	RYR1 RYR2	7.63e-06	3	56	2	10473538
Pubmed	Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.	RYR1 RYR2	7.63e-06	3	56	2	7959768
Pubmed	Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).	RYR1 RYR2	7.63e-06	3	56	2	12213830
Pubmed	The organization of proteins in the human red blood cell membrane. A review.	RYR1 RYR2	7.63e-06	3	56	2	4600883
Pubmed	Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.	RYR1 RYR2	7.63e-06	3	56	2	7635066
Pubmed	Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.	RYR1 RYR2	1.52e-05	4	56	2	9384575
Pubmed	A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.	RYR1 RYR2	1.52e-05	4	56	2	18206662
Pubmed	Increase of ryanodine receptors by dopamine D1 receptors is negatively regulated by γ-aminobutyric acid type B receptors in primary cultures of mouse cerebral cortical neurons.	RYR1 RYR2	1.52e-05	4	56	2	22504960
Pubmed	Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.	RYR1 RYR2	1.52e-05	4	56	2	9607712
Pubmed	S100A1 Protein Does Not Compete with Calmodulin for Ryanodine Receptor Binding but Structurally Alters the Ryanodine Receptor·Calmodulin Complex.	RYR1 RYR2	1.52e-05	4	56	2	27226555
Pubmed	OLFR734 Mediates Glucose Metabolism as a Receptor of Asprosin.	OR4M2 OR4M1	1.52e-05	4	56	2	31230984
Pubmed	Hypoxia differently modulates gene expression of inositol 1,4,5-trisphosphate receptors in mouse kidney and HEK 293 cell line.	RYR1 RYR2	1.52e-05	4	56	2	19120137
Pubmed	FKBP binding characteristics of cardiac microsomes from diverse vertebrates.	RYR1 RYR2	1.52e-05	4	56	2	11237759
Pubmed	Calmodulin modulates the termination threshold for cardiac ryanodine receptor-mediated Ca2+ release.	RYR1 RYR2	1.52e-05	4	56	2	23992453
Pubmed	Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.	RYR1 RYR2	1.52e-05	4	56	2	23482488
Pubmed	Ryanodine receptor calcium release channels: lessons from structure-function studies.	RYR1 RYR2	1.52e-05	4	56	2	23413940
Pubmed	Role of leaky neuronal ryanodine receptors in stress-induced cognitive dysfunction.	RYR1 RYR2	2.54e-05	5	56	2	22939628
Pubmed	Intracellular calcium-release channels: regulators of cell life and death.	RYR1 RYR2	2.54e-05	5	56	2	9124414
Pubmed	Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.	RYR1 RYR2	2.54e-05	5	56	2	19011160
Pubmed	Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons.	RYR1 RYR2	2.54e-05	5	56	2	23918386
Pubmed	Personal receptor repertoires: olfaction as a model.	OR4A8 OR52E1 OR4X1	3.20e-05	38	56	3	22908908
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	CACNA1I RYR1 RYR2	3.20e-05	38	56	3	30786075
Pubmed	Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2+ release in smooth muscle.	RYR1 RYR2	3.80e-05	6	56	2	19549818
Pubmed	HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization.	RYR1 RYR2	3.80e-05	6	56	2	19009018
Pubmed	Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.	RYR1 RYR2	3.80e-05	6	56	2	26025922
Pubmed	Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.	RYR1 RYR2	3.80e-05	6	56	2	23463619
Pubmed	IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.	RYR1 RYR2	3.80e-05	6	56	2	16844763
Pubmed	FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells.	RYR1 RYR2	3.80e-05	6	56	2	14592808
Pubmed	A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.	RYR1 RYR2	3.80e-05	6	56	2	20519450
Pubmed	Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.	RYR1 RYR2	3.80e-05	6	56	2	25966694
Pubmed	Novel human G-protein-coupled receptors.	OR51E1 OR52M1	5.32e-05	7	56	2	12732197
Pubmed	Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.	RYR1 RYR2	5.32e-05	7	56	2	11860456
Pubmed	Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax.	RYR1 RYR2	5.32e-05	7	56	2	20962236
Pubmed	Expert curation of the human and mouse olfactory receptor gene repertoires identifies conserved coding regions split across two exons.	OR2J3 OR7A10 OR4M2B	5.71e-05	46	56	3	32126975
Pubmed	Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation.	GABRP GABRA5	7.09e-05	8	56	2	18185516
Pubmed	Sequential docking, molecular differentiation, and positioning of T-Tubule/SR junctions in developing mouse skeletal muscle.	RYR1 RYR2	7.09e-05	8	56	2	11784029
Pubmed	Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.	RYR1 RYR2	7.09e-05	8	56	2	19033399
Pubmed	Different noses for different people.	OR4A8 OR4Q2	7.09e-05	8	56	2	12730696
Pubmed	AAV-mediated intramuscular delivery of myotubularin corrects the myotubular myopathy phenotype in targeted murine muscle and suggests a function in plasma membrane homeostasis.	RYR1 RYR2	1.14e-04	10	56	2	18434328
Pubmed	Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire.	OR3A2 OR3A3	1.39e-04	11	56	2	8004088
Pubmed	New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.	RYR1 RYR2	1.66e-04	12	56	2	19095005
Pubmed	MED12 regulates a transcriptional network of calcium-handling genes in the heart.	RYR1 RYR2	2.29e-04	14	56	2	28724790
Pubmed	Sequence, structure, and evolution of a complete human olfactory receptor gene cluster.	OR3A2 OR3A3	3.01e-04	16	56	2	10673334
Pubmed	Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype.	GABRP GABRA5	3.83e-04	18	56	2	19078961
Pubmed	Genome-wide meta-analysis of systolic blood pressure in children with sickle cell disease.	DPP10 ABCB11	3.83e-04	18	56	2	24058526
Pubmed	Early growth response 1 (Egr-1) directly regulates GABAA receptor α2, α4, and θ subunits in the hippocampus.	GABRP GABRA5	5.24e-04	21	56	2	25708312
Pubmed	Diet1 functions in the FGF15/19 enterohepatic signaling axis to modulate bile acid and lipid levels.	PLXDC2 ABCB11	5.24e-04	21	56	2	23747249
Pubmed	FoxP1 orchestration of ASD-relevant signaling pathways in the striatum.	DPP10 RYR1	5.76e-04	22	56	2	26494785
Pubmed	Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.	OR1Q1 OR7A10	6.87e-04	24	56	2	9119360
Pubmed	Distribution of olfactory receptor genes in the human genome.	OR3A2 OR3A3	9.37e-04	28	56	2	9500546
Pubmed	Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia, autism, and mental retardation.	DPP10 GABRA5	1.15e-03	31	56	2	19736351
Pubmed	Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse.	OR56A3 OR7A10	1.30e-03	33	56	2	17350283
Pubmed	A probabilistic classifier for olfactory receptor pseudogenes.	OR2J3 OR4X1	1.46e-03	35	56	2	16939646
Cytoband	11p15.4	OR51E1 OR52E1 OR56A3 OR52M1 OR52B6	4.76e-06	200	56	5	11p15.4
Cytoband	Ensembl 112 genes in cytogenetic band chr11q11	OR4A8 OR4S2 OR4C46	1.64e-05	40	56	3	chr11q11
Cytoband	Ensembl 112 genes in cytogenetic band chr11p15	OR51E1 OR52E1 OR56A3 OR52M1 OR52B6	6.27e-04	564	56	5	chr11p15
Cytoband	11p11.12	OR4A8 OR4C46	1.22e-03	42	56	2	11p11.12
Cytoband	1q23.1	OR10K2 OR6K6	1.46e-03	46	56	2	1q23.1
GeneFamily	Olfactory receptors, family 4	OR4M2 OR4A8 OR4S2 OR4Q2 OR4M1 OR4C46 OR4D11 OR4X1	9.32e-10	129	45	8	151
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR1 RYR2	1.81e-05	3	45	2	287
GeneFamily	Olfactory receptors, family 3	OR3A2 OR3A3	9.03e-05	6	45	2	150
GeneFamily	Olfactory receptors, family 52	OR52E1 OR52M1 OR52B6	2.45e-04	49	45	3	165
GeneFamily	Gamma-aminobutyric acid type A receptor subunits	GABRP GABRA5	1.01e-03	19	45	2	563
GeneFamily	Olfactory receptors, family 10	OR10W1 OR10K2	1.17e-02	66	45	2	157
ToppCell	COVID-19-Endothelial_cells-Arterial_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	VEGFC GABRP ADCY4 SLCO4A1 SV2C F8	9.46e-08	184	54	6	0f19494789f38ab1a420545e15e748ca7eb345c3
ToppCell	COVID-19-lung-Artery_EC\|lung / Disease (COVID-19 only), tissue and cell type	VEGFC ADCY4 SLCO4A1 SV2C F8	3.24e-06	188	54	5	eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell	COVID-19-lung-Artery_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	VEGFC ADCY4 SLCO4A1 SV2C F8	3.41e-06	190	54	5	07b675befcd1d0a9c90cb17b5d22323468325d51
ToppCell	LA-09._Endothelium_I\|World / Chamber and Cluster_Paper	VEGFC ADCY4 PLXDC2 SLCO4A1 F8	3.87e-06	195	54	5	fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	VEGFC ADCY4 SLCO4A1 OR7A10 F8	4.27e-06	199	54	5	e2d5c5cab102e67b0131b02392d81adaedc15965
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-Z\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PLXDC2 CH25H NAIP UNC93B1	3.30e-05	150	54	4	6c39e73a0b05d4b26589f333ce13924e3d373b8d
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	DPP10 SV2C RYR1 RYR2	4.14e-05	159	54	4	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VEGFC ADCY4 CH25H PAN2	5.25e-05	169	54	4	58136b8a0bf2dab45c91a053ef7225ea49ccb871
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VEGFC ADCY4 CH25H PAN2	5.25e-05	169	54	4	04c6ed38e1d1befba5ef5f37a3c1e045a0b163d6
ToppCell	facs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VEGFC ADCY4 CH25H F8	6.42e-05	178	54	4	ccd37575b60102f5e647c01546e8ff8fec638bd7
ToppCell	facs-Lung-18m-Endothelial-venous_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VEGFC ADCY4 CH25H F8	6.42e-05	178	54	4	87b04753650e45f12299c8456fb980d6c0d5961c
ToppCell	facs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VEGFC ADCY4 CH25H F8	6.42e-05	178	54	4	ebfae386a518ea33911ba3ff40464c94d18ef695
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	VEGFC GABRP ADCY4 F8	6.56e-05	179	54	4	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Mesenchymal_1\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	DPP10 CH25H EYA2 GABRA5	6.85e-05	181	54	4	7e3bcfa2ba5b98a7df5854aa6e7a31e9a71faa8a
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	OR51E1 DPP10 SV2C UNC80	7.61e-05	186	54	4	b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	VEGFC GABRP PLXDC2 F8	7.77e-05	187	54	4	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	Endothelial-A-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	VEGFC ADCY4 SLCO4A1 F8	7.77e-05	187	54	4	fd93f3f4b82dae3bf4eef245bfedc2a9e3251b61
ToppCell	Endothelial-A-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	VEGFC ADCY4 SLCO4A1 F8	8.26e-05	190	54	4	6e83fa0eb8cabe0ffb35375f16e6bf3755ec4977
ToppCell	RA-09._Endothelium_I\|RA / Chamber and Cluster_Paper	VEGFC ADCY4 PLXDC2 F8	8.60e-05	192	54	4	8a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCell	RV-09._Endothelium_I\|World / Chamber and Cluster_Paper	ADCY4 PLXDC2 SLCO4A1 F8	8.78e-05	193	54	4	e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCell	RV-09._Endothelium_I\|RV / Chamber and Cluster_Paper	ADCY4 PLXDC2 SLCO4A1 F8	8.95e-05	194	54	4	7b408096e717f2327c12aea35a8d5fc4621d3b06
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VEGFC ADCY4 CH25H F8	8.95e-05	194	54	4	e8102c8811333f04de7280b7d9b6b85cebb815ac
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VEGFC ADCY4 CH25H F8	8.95e-05	194	54	4	4b0d63babb8a46ff45731d5f82b29ccaf6c9402d
ToppCell	LV-09._Endothelium_I\|World / Chamber and Cluster_Paper	ADCY4 PLXDC2 SLCO4A1 F8	9.13e-05	195	54	4	19e0a6c3eae1615aaa39767300acd937dfcb2a7f
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	VEGFC ADCY4 SLCO4A1 F8	9.32e-05	196	54	4	915e4a7422058be246b54760df31e8a607310625
ToppCell	LA-09._Endothelium_I\|LA / Chamber and Cluster_Paper	VEGFC ADCY4 SLCO4A1 F8	9.50e-05	197	54	4	ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_capillary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	VEGFC ADCY4 SLCO4A1 F8	9.50e-05	197	54	4	81718164c9802ee20c860ffbda7e62d5e9a76f16
ToppCell	LV-09._Endothelium_I\|LV / Chamber and Cluster_Paper	ADCY4 PLXDC2 SLCO4A1 F8	9.50e-05	197	54	4	f9731d4d636e51b94a96805eee6afe9aedc175e3
ToppCell	Mild-Myeloid-Macrophages-FCN1_high\|Mild / Condition, Lineage, Cell class and cell subclass	PLXDC2 CH25H NAIP ADA2	9.69e-05	198	54	4	17aab4dc3b2cd6eb7dda77dd51bdc20490fcfe19
ToppCell	Transplant_Alveoli_and_parenchyma-Endothelial-Endothelial\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	VEGFC ADCY4 SLCO4A1 F8	9.69e-05	198	54	4	531b0f88c95f813e3914c96749f591e80ca321d0
ToppCell	Bronchial-NucSeq-Endothelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	VEGFC ADCY4 SLCO4A1 F8	9.88e-05	199	54	4	36a230b80096455df26c2e2c8c05fd6b231508c5
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_basal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CH25H EYA2 RYR1 GABRA5	9.88e-05	199	54	4	995d710d7302272e7951a5a5d766d1039089ee2b
ToppCell	severe_influenza-Classical_Monocyte\|World / disease group, cell group and cell class (v2)	PLXDC2 CH25H NAIP ADA2	9.88e-05	199	54	4	b8adbd6ff5e5602259118a69fd7c77e8348a27e4
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Basal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CH25H EYA2 RYR1 GABRA5	9.88e-05	199	54	4	e9c47f565a0a7737ecff68569d668aeb707ae5a6
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	VEGFC ADCY4 SLCO4A1 F8	1.01e-04	200	54	4	5ec31c1be6bcc4124e1489d136570f3de33cc2e9
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	VEGFC ADCY4 SLCO4A1 F8	1.01e-04	200	54	4	7547d6339f9380d031cfd2cce21ac9a12491e085
ToppCell	COVID-19-kidney-Epithelial_(EC)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DPP10 ABCB11 GABRA5	5.61e-04	133	54	3	a8abb6b54862123961ae6defbf251ee6e9575258
ToppCell	IIH-CD4-CD8_2\|IIH / Condition, Cell_class and T cell subcluster	AQP11 XPO4 SLC16A7	6.12e-04	137	54	3	5614a086f5f698e0965f3c7699cffefec5c3b87e
ToppCell	COVID-19-kidney-Technical/muscle_(EC)\|kidney / Disease (COVID-19 only), tissue and cell type	DPP10 XG RYR1	6.38e-04	139	54	3	64c35411bbe67acb5010dadc4b0b1be0f8b17737
ToppCell	droplet-Lung-nan-3m-Myeloid-intermediate_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC93B1 PKD1L2 RYR1	6.93e-04	143	54	3	4d11d53330a9197275a8851e1bbf55a113715a09
ToppCell	droplet-Lung-nan-3m-Myeloid-Intermediate_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC93B1 PKD1L2 RYR1	6.93e-04	143	54	3	8b9f4d87d5faac7752c83e1992491fc5550600f8
ToppCell	facs-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPP10 ABCB11 PKD1L2	7.07e-04	144	54	3	8bd042f12186f36bc5aabf6a0232270a448f4b58
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP10 ABCB11 UNC80	7.21e-04	145	54	3	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	COVID-19-kidney-Technical/muscle\|kidney / Disease (COVID-19 only), tissue and cell type	DPP10 HTR3B RYR2	7.65e-04	148	54	3	0dbd87078f54ee1c2f8ec64e8bac9dfddb9c181e
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DPP10 ABCB11 RYR1	7.95e-04	150	54	3	0205318a870e091add66ee4305747dda9f51510d
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	VEGFC GABRP ADCY4	8.11e-04	151	54	3	3b4c57bad61e17a573e6f8dc6b917fba5fd56c43
ToppCell	facs-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AQP11 ABCB11 SLC16A7	8.91e-04	156	54	3	e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	VEGFC SV2C F8	9.07e-04	157	54	3	275a4c6fef1fff8da2bdc48e3924ad05c5e5cfc8
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DPP10 SV2C UNC80	9.41e-04	159	54	3	7747cef94c55144fddcd024a7495318357f1351b
ToppCell	COVID-19-kidney-Epithelial_(EC)\|kidney / Disease (COVID-19 only), tissue and cell type	ADCY4 DPP10 F8	9.58e-04	160	54	3	0d4880f85565d8c540c94a8f8109147b3029279a
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D122\|Adult / Lineage, Cell type, age group and donor	VEGFC ADCY4 SLCO4A1	9.58e-04	160	54	3	0cfe130606af433b2aa90e0a20b6c44659dd6fd4
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DPP10 ABCB11 UNC80	9.93e-04	162	54	3	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	DPP10 RYR1 RYR2	1.01e-03	163	54	3	19c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	ADCY4 PLXDC2 RYR1	1.01e-03	163	54	3	f21951e63188eb0c04675a8f81a0da495c26c007
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	VEGFC ADCY4 SLCO4A1	1.03e-03	164	54	3	3cd80e6275f0f9b5667912139d15ebf5e6b17f2f
ToppCell	droplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLCO4A1 UNC93B1 RYR1	1.03e-03	164	54	3	cfe07a1ebed8aecb08d0476db71fe314998d54aa
ToppCell	droplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLCO4A1 UNC93B1 RYR1	1.03e-03	164	54	3	6d331e74efecb4733d87653f86cd67247be05025
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NAIP OR2J3 EYA2	1.05e-03	165	54	3	4b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	VEGFC ADCY4 RYR2	1.07e-03	166	54	3	ec719368295133da2f7ff587c5329ed6db1dd56d
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D122\|Adult / Lineage, Cell type, age group and donor	PLXDC2 NAIP OR3A3	1.07e-03	166	54	3	be284e2e596390f05305c7bcfc316f87b963fc0b
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D231\|Adult / Lineage, Cell type, age group and donor	ADCY4 SV2C F8	1.10e-03	168	54	3	aca34c51758c65925ad24110294a72b2dea6db72
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VEGFC CH25H EYA2	1.12e-03	169	54	3	a24d12199b1a6d9cb243b3a68f4109d3a30b2dcb
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-CD45____NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VEGFC CH25H EYA2	1.12e-03	169	54	3	573f85075d83a4baba41c3e24dc4d9831823a5e5
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PLXDC2 CH25H UNC93B1	1.12e-03	169	54	3	0867528101767fc65e93b3561480bf830c50368d
ToppCell	facs-Lung-nan-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VEGFC ADCY4 CH25H	1.14e-03	170	54	3	67d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCell	facs-Lung-nan-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VEGFC ADCY4 CH25H	1.14e-03	170	54	3	8e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_B_(ET)-Glut_ET_L5_FEZF2-Exc_L5_FEZF2_SCN7A\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	OR3A2 ABCB11 SV2C	1.14e-03	170	54	3	a0047551619547971d55165156f61f090948f902
ToppCell	droplet-Fat-Gat-18m-Lymphocytic-B_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1I UNC93B1 RYR1	1.14e-03	170	54	3	5185187ecf26b4c9eaa0c01ad52697ab8d075cc7
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9\|TCGA-Bladder / Sample_Type by Project: Shred V9	GABRP ABCB11 EYA2	1.16e-03	171	54	3	adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADCY4 OR10W1 F8	1.16e-03	171	54	3	b3e6e31dfe3623b960ccf692fdbd236fa4039923
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-Progenitor_(NEUROG3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	OR51E1 DPP10 EYA2	1.16e-03	171	54	3	c54dcad75fc378da1943009d7dd872b39ea337c0
ToppCell	droplet-Thymus-nan-21m-Myeloid-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRP UNC93B1 RYR1	1.16e-03	171	54	3	8bed33f61f7d12a1ac4fba33f730d839f5ee7bef
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VEGFC ADCY4 CH25H	1.18e-03	172	54	3	fc092a0631555d79e00ef9890cbd806e15bca2d4
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VEGFC ADCY4 CH25H	1.18e-03	172	54	3	745725bd10c82017d678463b8fef0d2dcf09a8fd
ToppCell	368C-Endothelial_cells-Endothelial-B_(Artery)\|368C / Donor, Lineage, Cell class and subclass (all cells)	ADCY4 SLCO4A1 F8	1.20e-03	173	54	3	22200fe74e33e2beae0eed289ca8476bbc0b1b2d
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-Progenitor_(NEUROG3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	OR51E1 DPP10 EYA2	1.20e-03	173	54	3	cc2e489b91562a0c6fe863e2f796f4a7d2ca27dd
ToppCell	368C-Endothelial_cells-Endothelial-B_(Artery)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	ADCY4 SLCO4A1 F8	1.20e-03	173	54	3	ec88e871b49331fca59bc610a8ae58e2d5e76bc1
ToppCell	droplet-Liver-Npc-18m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SV2C UNC93B1 PKD1L2	1.20e-03	173	54	3	9ba55e21d1037ec3150d77895e52f0b051df65da
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VEGFC ADCY4 F8	1.22e-03	174	54	3	18ab52d8bbca0507fee220e0c4fc765fc47dda34
ToppCell	facs-Kidney-nan-18m-Myeloid-macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CH25H UNC93B1 UNC80	1.24e-03	175	54	3	cec941edec6849f2fb602c08fd1eed6d0345f934
ToppCell	facs-Kidney-nan-18m-Myeloid\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CH25H UNC93B1 UNC80	1.24e-03	175	54	3	2cb0d07a47bc645cfa690bb853e11d657af19ede
ToppCell	368C-Endothelial_cells-Endothelial-D\|368C / Donor, Lineage, Cell class and subclass (all cells)	ADCY4 SLCO4A1 F8	1.24e-03	175	54	3	c4088b5f9fa145869cf5dd8bee7680b1c8fada42
ToppCell	368C-Endothelial_cells-Endothelial-D-\|368C / Donor, Lineage, Cell class and subclass (all cells)	ADCY4 SLCO4A1 F8	1.24e-03	175	54	3	ca0d3e3a0a271cccdd3881b055fecb626712478d
ToppCell	facs-Kidney-nan-18m-Myeloid-macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CH25H UNC93B1 UNC80	1.24e-03	175	54	3	24d58e2f6d36124bde0f2c6f5357b9161bc5f476
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-SMG_basal_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	GABRP CH25H UNC80	1.26e-03	176	54	3	045b12c90f7dd49a9778dadcdf8f18125b380531
ToppCell	Adult-Endothelial-endothelial_cell_of_vein\|Adult / Lineage, Cell type, age group and donor	VEGFC ADCY4 SLCO4A1	1.26e-03	176	54	3	043683c61c5d1a7f8a4666a612310246bd3d83a2
ToppCell	COPD-Epithelial-Basal\|Epithelial / Disease state, Lineage and Cell class	PLXDC2 CH25H EYA2	1.30e-03	178	54	3	441d1dba720141891b11f404744c59834d80e6c5
ToppCell	367C-Endothelial_cells-Endothelial-B_(Artery)\|367C / Donor, Lineage, Cell class and subclass (all cells)	SLCO4A1 SV2C F8	1.30e-03	178	54	3	e1e96a0e3ff718ebf676a982bc63e8ced6984059
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-basal_late\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CH25H EYA2 UNC80	1.30e-03	178	54	3	03f22485074b3cbf9a6ad4d543c5bbfa826dc741
ToppCell	367C-Endothelial_cells-Endothelial-B_(Artery)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	SLCO4A1 SV2C F8	1.30e-03	178	54	3	363e8b23b3834692a8a79e5fdc7b43bd3a4dab5e
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	PLXDC2 NAIP SLC16A7	1.32e-03	179	54	3	cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADCY4 SV2C F8	1.32e-03	179	54	3	40c65e8623547aeb80f9cd2366e29072467ce069
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	VEGFC SLCO4A1 F8	1.32e-03	179	54	3	d2db9e70b780643f1e004c41a70464d0abe26088
ToppCell	368C-Endothelial_cells-Endothelial-E\|368C / Donor, Lineage, Cell class and subclass (all cells)	ADCY4 SLCO4A1 F8	1.34e-03	180	54	3	8ab16a0b9053bffc07b569a4f9e71749f56dde7e
ToppCell	Endothelial-A-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	VEGFC OR51E1 SLCO4A1	1.34e-03	180	54	3	4c3376169770ee9f9283daae44c17f35e46bfd19
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NAIP EYA2 SLC16A7	1.34e-03	180	54	3	9e09b3dfe344b5d50520711513d389865d73a861
ToppCell	368C-Endothelial_cells-Endothelial-E-\|368C / Donor, Lineage, Cell class and subclass (all cells)	ADCY4 SLCO4A1 F8	1.34e-03	180	54	3	394cd465b88429b70eebb2957480dffcbc51cfe7
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PLXDC2 NAIP UNC93B1	1.34e-03	180	54	3	6f8fa9fa91cd25b92584972bb34d90c483222f52
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(other)\|COVID-19 / group, cell type (main and fine annotations)	ADCY4 SLCO4A1 F8	1.37e-03	181	54	3	26eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Mesenchymal_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	DPP10 EYA2 GABRA5	1.37e-03	181	54	3	9b2d207dc9fc2228a1555ed360286bb7c2d988ff
Computational	Ion channels.	GABRP RYR1 RYR2 GABRA5	4.71e-06	70	18	4	MODULE_316
Computational	Ion channels.	GABRP RYR1 GABRA5	1.12e-05	27	18	3	MODULE_214
Computational	Neurotransmitter (GABA) receptor.	GABRP GABRA5	2.75e-04	15	18	2	MODULE_215
Computational	Neighborhood of FOS	NAIP ADA2	2.09e-03	41	18	2	GNF2_FOS
Drug	baclofen	GABRP ADCY4 CACNA1I RYR1 RYR2 GABRA5	4.24e-06	191	51	6	CID000002284
Drug	halothane	GABRP ADCY4 CH25H CACNA1I RYR1 RYR2 GABRA5	6.11e-06	314	51	7	CID000003562
Drug	SK&F 82958	ADCY4 RYR1 RYR2	1.00e-05	19	51	3	ctd:C071262
Drug	EBOB	GABRP HTR3B GABRA5	1.18e-05	20	51	3	CID000115223
Drug	2-hydroxyheptanoic acid	RYR1 RYR2	1.47e-05	3	51	2	CID002750949
Drug	Ryanodyl 3-(pyridine-3-carboxylate	RYR1 RYR2	1.47e-05	3	51	2	CID005748312
Drug	8N3-cADPR	RYR1 RYR2	1.47e-05	3	51	2	CID000127713
Drug	2-hydroxycarbazole	RYR1 RYR2	1.47e-05	3	51	2	CID000093551
Drug	aminodantrolene	RYR1 RYR2	1.47e-05	3	51	2	CID009570289
Drug	cis-diammineplatinum(II	RYR1 RYR2	1.47e-05	3	51	2	CID000159790
Drug	nimodipine	GABRP CACNA1I RYR1 RYR2 GABRA5	1.81e-05	145	51	5	CID000004497
Drug	procaine	GABRP CACNA1I RYR1 RYR2 GABRA5	2.35e-05	153	51	5	CID000004914
Drug	lidocaine	GABRP ADCY4 RYR1 RYR2 GABRA5	2.91e-05	160	51	5	CID000003676
Drug	SC 38249	RYR1 RYR2	2.94e-05	4	51	2	CID000134834
Drug	AC1L1U7A	RYR1 RYR2	2.94e-05	4	51	2	CID000035682
Drug	PCB74	RYR1 RYR2	2.94e-05	4	51	2	CID000036218
Drug	148504-47-6	RYR1 RYR2	2.94e-05	4	51	2	CID006444275
Drug	etazolate	GABRP ADCY4 GABRA5	3.71e-05	29	51	3	CID000003277
Drug	gabapentin	GABRP CACNA1I RYR1 RYR2 GABRA5	3.78e-05	169	51	5	CID000003446
Drug	2,4-xylidinothiazoline	XG RYR1 RYR2	4.12e-05	30	51	3	CID000099296
Drug	riluzole	GABRP CACNA1I RYR1 RYR2 GABRA5	4.35e-05	174	51	5	CID000005070
Drug	A 68930	RYR1 RYR2	4.90e-05	5	51	2	ctd:C065380
Drug	CNS 1145	CACNA1I RYR1 RYR2	5.51e-05	33	51	3	CID000190902
Drug	IHC-64	CACNA1I RYR1 RYR2	5.51e-05	33	51	3	CID000162753
Drug	AC1O528X	RYR1 RYR2	7.34e-05	6	51	2	CID006475857
Drug	NSC114784	RYR1 RYR2	7.34e-05	6	51	2	CID000419425
Drug	MBED	RYR1 RYR2	7.34e-05	6	51	2	CID000129958
Drug	chloro-m-cresol	RYR1 RYR2	7.34e-05	6	51	2	CID000012008
Drug	secobarbital	GABRP NAIP GABRA5	7.80e-05	37	51	3	CID000005193
Drug	Azumoleno	RYR1 RYR2	1.03e-04	7	51	2	CID000056259
Drug	[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate	RYR1 RYR2	1.03e-04	7	51	2	CID009547999
Drug	Br2BAPTA	RYR1 RYR2	1.03e-04	7	51	2	CID003081001
Drug	barbital	GABRP NAIP GABRA5	1.14e-04	42	51	3	CID000002294
Drug	thiopental	GABRP RYR1 RYR2 GABRA5	1.16e-04	112	51	4	CID003000715
Drug	thymol	GABRP RYR1 GABRA5	1.50e-04	46	51	3	CID000006989
Drug	PCB 95	RYR1 RYR2	2.19e-04	10	51	2	CID000038012
Drug	lanthanum	ADCY4 CACNA1I RYR1 RYR2	2.45e-04	136	51	4	CID000023926
Drug	Etomidate	CACNA1I GABRA5	2.67e-04	11	51	2	ctd:D005045
Drug	R 478	RYR1 RYR2	2.67e-04	11	51	2	CID000084223
Drug	Bu-1014	GABRP GABRA5	2.67e-04	11	51	2	CID015942721
Drug	fosazepam	GABRP GABRA5	2.67e-04	11	51	2	CID000037114
Drug	2,3,6,2',3',6'-hexachlorobiphenyl	RYR1 RYR2	2.67e-04	11	51	2	ctd:C010498
Drug	Zapizolam	GABRP GABRA5	2.67e-04	11	51	2	CID000068832
Drug	C19H18ClN3O	GABRP GABRA5	2.67e-04	11	51	2	CID000027452
Drug	8-amino-cADPR	RYR1 RYR2	2.67e-04	11	51	2	CID003081323
Drug	flutoprazepam	GABRP GABRA5	2.67e-04	11	51	2	CID000003400
Drug	Reclazepam	GABRP GABRA5	2.67e-04	11	51	2	CID003052777
Drug	iclazepam	GABRP GABRA5	2.67e-04	11	51	2	CID000068777
Drug	Arfendazam	GABRP GABRA5	2.67e-04	11	51	2	CID000065803
Drug	menitrazepam	GABRP GABRA5	2.67e-04	11	51	2	CID000189875
Drug	PCB 66	RYR1 RYR2	2.67e-04	11	51	2	CID000036185
Drug	Serin hydrazid	GABRP GABRA5	2.67e-04	11	51	2	CID000041637
Drug	sulazepam	GABRP GABRA5	2.67e-04	11	51	2	CID000017931
Drug	tectoridin	RYR1 RYR2	2.67e-04	11	51	2	CID005281810
Drug	elfazepam	GABRP GABRA5	2.67e-04	11	51	2	CID000065445
Drug	camazepam	GABRP GABRA5	2.67e-04	11	51	2	CID000037367
Drug	uldazepam	GABRP GABRA5	2.67e-04	11	51	2	CID000034274
Drug	gidazepam	GABRP GABRA5	2.67e-04	11	51	2	CID000121919
Drug	triflubazam	GABRP GABRA5	2.67e-04	11	51	2	CID000031157
Drug	fletazepam	GABRP GABRA5	2.67e-04	11	51	2	CID000036834
Drug	Cinildipine	CACNA1I RYR1 RYR2	2.70e-04	56	51	3	CID000002752
Drug	SB-205384	GABRP GABRA5	3.20e-04	12	51	2	CID000197690
Drug	U-93631	GABRP GABRA5	3.20e-04	12	51	2	CID000197626
Drug	haloxazolam	GABRP GABRA5	3.20e-04	12	51	2	CID000003563
Drug	pivoxazepam	GABRP GABRA5	3.20e-04	12	51	2	CID000068722
Drug	Ryanodine	RYR1 RYR2	3.20e-04	12	51	2	ctd:D012433
Drug	razobazam	GABRP GABRA5	3.20e-04	12	51	2	CID000071228
Drug	doxefazepam	GABRP GABRA5	3.20e-04	12	51	2	CID000038668
Drug	5 beta-pregnanediol	GABRP ABCB11 GABRA5	3.31e-04	60	51	3	CID000012547
Drug	nilvadipine	CACNA1I RYR1 RYR2	3.31e-04	60	51	3	CID000004494
Drug	IAA-94	CACNA1I RYR1 RYR2	3.48e-04	61	51	3	CID000003667
Drug	Bay K 8644	ADCY4 CACNA1I RYR1 RYR2	3.56e-04	150	51	4	CID000002303
Drug	lead compounds	ADCY4 CACNA1I RYR1 RYR2	3.56e-04	150	51	4	CID000073212
Drug	MW 1	VEGFC XPO4 RYR1 RYR2	3.65e-04	151	51	4	CID000073965
Drug	naphthalene-diisocyanate	ADCY4 AQP11 F8	3.65e-04	62	51	3	CID003033874
Drug	cinolazepam	GABRP GABRA5	3.78e-04	13	51	2	CID003033621
Drug	AC1MVFYM	GABRP GABRA5	3.78e-04	13	51	2	CID003707225
Drug	nerisopam	GABRP GABRA5	3.78e-04	13	51	2	CID000065875
Drug	flutazolam	GABRP GABRA5	3.78e-04	13	51	2	CID000003398
Drug	alpha IMGBL	GABRP GABRA5	3.78e-04	13	51	2	CID000131516
Drug	4-PIOL	GABRP GABRA5	3.78e-04	13	51	2	CID000125520
Drug	Ro 11-3128	GABRP GABRA5	3.78e-04	13	51	2	CID000093364
Drug	Mibefradil	ABCB11 CACNA1I	3.78e-04	13	51	2	ctd:D020748
Drug	metaclazepam	GABRP GABRA5	3.78e-04	13	51	2	CID000071272
Drug	lercanidipine	CACNA1I RYR1 RYR2	3.82e-04	63	51	3	CID000065866
Drug	lindane	GABRP RYR1 RYR2 GABRA5	3.93e-04	154	51	4	CID000000727
Drug	picrotoxinine	VEGFC GABRP GABRA5	4.19e-04	65	51	3	CID000004816
Drug	Me-lex	GABRP GABRA5	4.40e-04	14	51	2	CID000004177
Drug	beta-CCt	GABRP GABRA5	4.40e-04	14	51	2	CID000124514
Drug	ethyl loflazepate	GABRP GABRA5	4.40e-04	14	51	2	CID000003299
Drug	Eudragit RL	VEGFC ALG1	4.40e-04	14	51	2	CID000104804
Drug	gallopamil	CACNA1I RYR1 RYR2	4.58e-04	67	51	3	CID000001234
Drug	AC1L2AC7	CACNA1I RYR1 RYR2	5.00e-04	69	51	3	CID000068733
Drug	loprazolam	GABRP GABRA5	5.07e-04	15	51	2	CID003033860
Drug	SR 95103	GABRP GABRA5	5.07e-04	15	51	2	CID000125958
Drug	FPL 64176	RYR1 RYR2	5.07e-04	15	51	2	CID000003423
Drug	premazepam	GABRP GABRA5	5.07e-04	15	51	2	CID000072104
Drug	Gvapspat amide	RYR1 RYR2	5.07e-04	15	51	2	CID000125015
Drug	pinazepam	GABRP GABRA5	5.07e-04	15	51	2	CID000040391
Drug	fludiazepam	GABRP GABRA5	5.07e-04	15	51	2	CID000003369
Disease	malignant hyperthermia (implicated_via_orthology)	RYR1 RYR2	7.77e-06	3	48	2	DOID:8545 (implicated_via_orthology)
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR1 RYR2	7.77e-06	3	48	2	DOID:3529 (implicated_via_orthology)
Disease	Autism Spectrum Disorders	DPP10 UNC80 RYR2 GABRA5	1.13e-05	85	48	4	C1510586
Disease	depressive disorder (is_implicated_in)	HTR3B GABRA5	3.47e-04	17	48	2	DOID:1596 (is_implicated_in)
Disease	1,5 anhydroglucitol measurement	PKD1L2 MGAM2	1.02e-03	29	48	2	EFO_0008009

Protein segments in the cluster

Peptide	Gene	Start	Entry
HLKCNFFSDFGSLMT	NAIP	1161	Q13075
LAMHGFSVTLLGFCN	ALG1	56	Q9BT22
LIGHFFTICMAFLVL	HTR3B	301	O95264
LMFVGSLCAFLHGIA	ABCB11	61	O95342
TLGFLSCSLFLHMSF	ADCY4	726	Q8NFM4
TLDLILFCFPFHMSQ	DOP1A	246	Q5JWR5
SFSPMNQHFLLFCEG	DPP10	481	Q8N608
LFFLHFAGASEMFLL	OR4M2B	101	A0A0X1KG70
ISFEGCLTQMFFIHL	OR52E1	91	Q8NGJ3
SCMTQIFLFHLLGGA	OR4D11	96	Q8NGI4
LACELGFLFHMLDLS	PAN2	556	Q504Q3
QMAFFIALGSADCFL	OR10W1	91	Q8NGF6
MINLYGAHTFFLCLE	MGAM2	251	Q2M2H8
HMLELFIAANSGFIC	OR4C46	191	A6NHA9
FDACLLQMFAIHSLS	OR51E1	96	Q8TCB6
CLSQLFFFHLLAGMD	OR3A2	106	P47893
FFFHLLAGMDCFLLT	OR3A2	111	P47893
CLSQLFFFHLLAGMD	OR3A3	106	P47888
FFFHLLAGMDCFLLT	OR3A3	111	P47888
LISFDGCLTQMFFIH	OR52B6	111	Q8NGF0
GCLTQMFFIHFLFIH	OR52B6	116	Q8NGF0
LFFLHFVGASEMFLL	OR4M1	101	Q8NGD0
LFFLHFAGASEMFLL	OR4M2	101	Q8NGB6
QLFFLHFVGAAEMFL	OR4Q2	101	P0C623
MLQLFGVHFFGCTEI	OR4S2	96	Q8NH73
SLKGCLTQMFSLHFF	OR4X1	91	Q8NH49
FFSFAIMFNGVCHLL	SLC16A7	316	O60669
LLFCISMNLSSHFGF	GABRA5	16	P31644
QTLLMDLGQFLLFCH	F8	316	P00451
LCNHLTFFGSTFLVM	PKD1L2	1311	Q7Z442
GASMFFICLFLHIGR	MT-CYB	86	P00156
FSILGMHIFGCKFSL	CACNA1I	776	Q9P0X4
ALDFMCFLALLFLFS	TMEM63B	46	Q5T3F8
ALCFLLLAVAMSFFG	ADA2	11	Q9NZK5
NNFFFAAHLLDIAMG	RYR1	4806	P21817
NFFFAAHLLDIAMGF	RYR2	4736	Q92736
HHILFCLLLFDMEFF	CH25H	126	O95992
MNYSLHLAFVCLSLF	GABRP	1	O00591
SVAGCLLQMYFFHSL	OR6K6	121	Q8NGW6
MFSFLFLGCSHSFLL	OR10K2	101	Q6IF99
AMLHTFLIGQLIFCA	OR1Q1	156	Q15612
FGTCGAHLMAVSLFF	OR2J3	241	O76001
SFPACMGQLFIEHLF	OR4A8	91	P0C604
LDACLGQMFLIHCFA	OR52M1	96	Q8NGK5
MIFNLADTHLFFNDL	EYA2	311	O00167
AFLCFLMHARGQRDF	XG	11	P55808
LLICMSVNGFFAFLS	SV2C	221	Q496J9
MCFFLLFVGLDNFLL	OR7A10	101	O76100
AAGVMLLCHFFTDQF	PLXDC2	11	Q6UX71
ALSTCGSHFMLILFF	OR56A3	241	Q8NH54
LFFLCAAAFLQGMTV	SLCO4A1	106	Q96BD0
NPALALSLHFMCFDE	AQP11	216	Q8NBQ7
LSLHFMCFDEAFPQF	AQP11	221	Q8NBQ7
SLNFLFFMLAAVALH	PIGV	121	Q9NUD9
FFMLAAVALHDLGCL	PIGV	126	Q9NUD9
SFFHLSFACAQLPMI	UNC93B1	226	Q9H1C4
MHLLGFFSVACSLLA	VEGFC	1	P49767
ILFNFLMDFLTNCIG	XPO4	826	Q9C0E2
NNVVDFLHALLGFCM	UNC80	856	Q8N2C7
VFMCFFVGNDFLPHL	XRN2	336	Q9H0D6
GSLELFFDHCLFTML	TMEM214	191	Q6NUQ4
ALTLSGMFLYHNCEF	SLC35E4	316	Q6ICL7