Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphosphatidylethanolamine binding

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B2 MAP1LC3B

5.54e-08191125GO:0008429
GeneOntologyMolecularFunctionNAD+ nucleosidase activity

IL1RL2 IL1RAPL1 IL1RAP

3.64e-05121123GO:0003953
GeneOntologyMolecularFunctionNAD+ nucleotidase, cyclic ADP-ribose generating

IL1RL2 IL1RAPL1 IL1RAP

9.12e-05161123GO:0061809
GeneOntologyMolecularFunctionenzyme regulator activity

A2M RGPD4 DENND5B RASGRF1 HACD3 OBSCN APOH NEK9 KAT2B ABCE1 RGPD3 PLCB1 FGF13 C5 DENND5A BSN MAPK8 ARHGAP20 GCN1 IQGAP3

1.11e-04141811220GO:0030234
GeneOntologyMolecularFunctioncytoskeletal protein binding

CACNB2 OBSCN GABARAP SAXO2 MAP1LC3A SORBS1 TUBGCP4 GABARAPL1 MAP1LC3B2 ARC FGF13 MAP1LC3B MAPK8 PLS1 IQGAP3 SNTB2

4.14e-04109911216GO:0008092
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RGPD4 DENND5B RASGRF1 HACD3 OBSCN RGPD3 PLCB1 DENND5A ARHGAP20 IQGAP3

5.70e-0450711210GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RGPD4 DENND5B RASGRF1 HACD3 OBSCN RGPD3 PLCB1 DENND5A ARHGAP20 IQGAP3

5.70e-0450711210GO:0030695
GeneOntologyMolecularFunctionstructural constituent of presynaptic active zone

RIMBP2 BSN

8.54e-0481122GO:0098882
GeneOntologyMolecularFunctioninterleukin-1 receptor activity

IL1RL2 IL1RAP

8.54e-0481122GO:0004908
GeneOntologyMolecularFunctionDNA topoisomerase activity

TOP1MT TOP2B

8.54e-0481122GO:0003916
GeneOntologyMolecularFunctionGTPase binding

RGPD4 DENND5B EPRS1 RASGRF1 IARS1 RGPD3 DENND5A IQGAP3

9.64e-043601128GO:0051020
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

EPRS1 DIS3L IARS1 SMARCAL1 POLRMT RECQL5 DDX54 TOP1MT TOP2B MOV10 HELLS

1.00e-0364511211GO:0140640
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of cytosolic calcium levels

CACNB2 RIMBP2

1.09e-0391122GO:0099511
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

CACNB2 RIMBP2

1.09e-0391122GO:0099626
GeneOntologyBiologicalProcesscellular response to nitrogen levels

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B2 MAP1LC3B

3.17e-09121115GO:0043562
GeneOntologyBiologicalProcesscellular response to nitrogen starvation

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B2 MAP1LC3B

3.17e-09121115GO:0006995
GeneOntologyBiologicalProcesscellular response to nutrient levels

DAPL1 CYP27B1 GABARAP MAP1LC3A MAP3K5 KAT2B GABARAPL1 MAP1LC3B2 ALB MAP1LC3B MAPK8 GCN1

1.78e-0826211112GO:0031669
GeneOntologyBiologicalProcesscellular response to starvation

DAPL1 GABARAP MAP1LC3A MAP3K5 GABARAPL1 MAP1LC3B2 ALB MAP1LC3B MAPK8 GCN1

6.22e-0818511110GO:0009267
GeneOntologyBiologicalProcessresponse to nutrient levels

A2M DAPL1 CYP27B1 GABARAP MAP1LC3A MAP3K5 KAT2B GABARAPL1 MAP1LC3B2 AACS ALB MAP1LC3B MAPK8 GCN1 CNR1

3.76e-0756611115GO:0031667
GeneOntologyBiologicalProcessresponse to starvation

DAPL1 GABARAP MAP1LC3A MAP3K5 GABARAPL1 MAP1LC3B2 ALB MAP1LC3B MAPK8 GCN1

4.53e-0722911110GO:0042594
GeneOntologyBiologicalProcessorganelle disassembly

ATG2B GABARAP MAP1LC3A GABARAPL1 MAP1LC3B2 ABCE1 LRBA MAP1LC3B GCN1

1.61e-062041119GO:1903008
GeneOntologyBiologicalProcessautophagy of mitochondrion

ATG2B GABARAP MAP1LC3A GABARAPL1 MAP1LC3B2 LRBA MAP1LC3B

2.77e-061141117GO:0000422
GeneOntologyBiologicalProcessautophagosome assembly

ATG2B GABARAP MAP1LC3A GABARAPL1 MAP1LC3B2 LRBA MAP1LC3B

4.12e-061211117GO:0000045
GeneOntologyBiologicalProcessautophagosome organization

ATG2B GABARAP MAP1LC3A GABARAPL1 MAP1LC3B2 LRBA MAP1LC3B

6.29e-061291117GO:1905037
GeneOntologyBiologicalProcesscellular response to amino acid starvation

DAPL1 MAP1LC3A MAP3K5 MAPK8 GCN1

1.27e-05561115GO:0034198
GeneOntologyBiologicalProcessresponse to amino acid starvation

DAPL1 MAP1LC3A MAP3K5 MAPK8 GCN1

1.93e-05611115GO:1990928
GeneOntologyBiologicalProcessautophagosome maturation

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B2 MAP1LC3B

3.52e-05691115GO:0097352
GeneOntologyBiologicalProcesssynaptic signaling

CACNB2 PDE9A RASGRF1 APBA2 GABARAP SORBS1 SLC38A1 IL1RAPL1 EIF4E PLCB1 ARC RIMBP2 BSN MAPK8 IL1RAP CNR1

6.67e-0597611116GO:0099536
GeneOntologyBiologicalProcesstrans-synaptic signaling

CACNB2 PDE9A RASGRF1 APBA2 GABARAP SLC38A1 IL1RAPL1 EIF4E PLCB1 ARC RIMBP2 BSN MAPK8 IL1RAP CNR1

1.53e-0493911115GO:0099537
GeneOntologyBiologicalProcessMHC protein complex assembly

HLA-DRB1 HLA-DRB4 TAPBP

1.88e-04211113GO:0002396
GeneOntologyBiologicalProcesspeptide antigen assembly with MHC protein complex

HLA-DRB1 HLA-DRB4 TAPBP

1.88e-04211113GO:0002501
GeneOntologyBiologicalProcesscellular response to oxygen-glucose deprivation

MAP1LC3A MAPK8

2.84e-0451112GO:0090650
GeneOntologyCellularComponentautolysosome

HLA-DRB1 MAP1LC3A MAP1LC3B2 MAP1LC3B

2.42e-06181144GO:0044754
GeneOntologyCellularComponentsecondary lysosome

HLA-DRB1 MAP1LC3A MAP1LC3B2 MAP1LC3B

1.14e-05261144GO:0005767
GeneOntologyCellularComponentautophagosome membrane

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B2 MAP1LC3B

1.47e-05571145GO:0000421
GeneOntologyCellularComponentcytoplasmic region

GABARAP SAXO2 AK8 GABARAPL1 MAP1LC3B2 ARC RIMBP2 MAP1LC3B BSN MAPK8

2.82e-0536011410GO:0099568
GeneOntologyCellularComponentlumenal side of endoplasmic reticulum membrane

HLA-DRB1 HLA-DRB4 SPPL2A TAPBP

3.86e-05351144GO:0098553
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

GABARAP SAXO2 AK8 GABARAPL1 MAP1LC3B2 ARC MAP1LC3B BSN MAPK8

6.09e-053171149GO:0032838
GeneOntologyCellularComponentlumenal side of membrane

HLA-DRB1 HLA-DRB4 SPPL2A TAPBP

1.36e-04481144GO:0098576
GeneOntologyCellularComponentautophagosome

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B2 MAP1LC3B

4.92e-041191145GO:0005776
GeneOntologyCellularComponentmembrane attack complex

C5 C8B

6.08e-0471142GO:0005579
GeneOntologyCellularComponentcytoplasmic periphery of the nuclear pore complex

RGPD4 RGPD3

8.08e-0481142GO:1990723
GeneOntologyCellularComponentcell cortex

FRYL HMCN1 CSNK1G2 ARC RIMBP2 BSN PLS1 IQGAP3

9.81e-043711148GO:0005938
GeneOntologyCellularComponentnuclear pore cytoplasmic filaments

RGPD4 RGPD3

1.29e-03101142GO:0044614
GeneOntologyCellularComponenttrans-Golgi network

HLA-DRB1 HLA-DRB4 ST3GAL1 NSG2 DENND5A LRBA BSN

1.46e-033061147GO:0005802
GeneOntologyCellularComponentglutamatergic synapse

MAP1LC3A IL1RAPL1 NSG2 EIF4E PRICKLE2 PLCB1 ARC RIMBP2 BSN IL1RAP CDH6 CNR1

1.68e-0381711412GO:0098978
GeneOntologyCellularComponentvacuolar membrane

HLA-DRB1 HLA-DRB4 GABARAP MAP1LC3A SPPL2A GABARAPL1 MAP1LC3B2 LRBA MAP1LC3B

1.85e-035071149GO:0005774
GeneOntologyCellularComponentsupramolecular fiber

HLA-DRB1 OBSCN GABARAP SAXO2 MAP1LC3A TUBGCP4 PPL KAT2B GABARAPL1 MAP1LC3B2 FGF13 MAP1LC3B PLS1 SNTB2 AHNAK2

1.86e-03117911415GO:0099512
GeneOntologyCellularComponentaminoacyl-tRNA synthetase multienzyme complex

EPRS1 IARS1

1.88e-03121142GO:0017101
GeneOntologyCellularComponentsupramolecular polymer

HLA-DRB1 OBSCN GABARAP SAXO2 MAP1LC3A TUBGCP4 PPL KAT2B GABARAPL1 MAP1LC3B2 FGF13 MAP1LC3B PLS1 SNTB2 AHNAK2

1.99e-03118711415GO:0099081
GeneOntologyCellularComponentdendrite

RASGRF1 APBA2 IL1RAPL1 GABARAPL1 NSG2 MAP1LC3B2 ARC ROBO1 FGF13 MAP1LC3B BSN MAPK8

2.52e-0385811412GO:0030425
GeneOntologyCellularComponentdendritic tree

RASGRF1 APBA2 IL1RAPL1 GABARAPL1 NSG2 MAP1LC3B2 ARC ROBO1 FGF13 MAP1LC3B BSN MAPK8

2.57e-0386011412GO:0097447
GeneOntologyCellularComponentannulate lamellae

RGPD4 RGPD3

2.57e-03141142GO:0005642
GeneOntologyCellularComponentmicrotubule

GABARAP SAXO2 MAP1LC3A TUBGCP4 GABARAPL1 MAP1LC3B2 FGF13 MAP1LC3B SNTB2

2.59e-035331149GO:0005874
HumanPhenoAbnormality of humoral immunity

HYOU1 HLA-DRB1 SMARCAL1 CASP10 SLC46A1 SPPL2A MTHFD1 ALB C5 LRBA C8B HELLS

1.27e-063503412HP:0005368
HumanPhenoAbnormal B cell morphology

HYOU1 HLA-DRB1 SMARCAL1 CASP10 SLC46A1 SPPL2A MTHFD1 ALB C5 LRBA C8B HELLS

2.10e-063673412HP:0002846
HumanPhenoImmunoglobulin abnormality

HYOU1 HLA-DRB1 SMARCAL1 CASP10 SLC46A1 SPPL2A MTHFD1 ALB LRBA HELLS

1.38e-052953410HP:0100032
HumanPhenoAbnormal circulating immunoglobulin concentration

HYOU1 HLA-DRB1 SMARCAL1 CASP10 SLC46A1 SPPL2A MTHFD1 ALB LRBA HELLS

1.38e-052953410HP:0010701
HumanPhenoAbnormality of B cell physiology

HYOU1 HLA-DRB1 SMARCAL1 CASP10 SLC46A1 SPPL2A MTHFD1 ALB LRBA HELLS

1.42e-052963410HP:0005372
HumanPhenoAbnormal lymphocyte morphology

HYOU1 HLA-DRB1 SMARCAL1 CASP10 SLC46A1 SPPL2A SF3B1 MTHFD1 ALB C5 LRBA C8B HELLS

1.51e-055243413HP:0004332
HumanPhenoAbnormal lymphocyte physiology

HYOU1 HLA-DRB1 SMARCAL1 CASP10 SLC46A1 SPPL2A MTHFD1 ALB LRBA HELLS

3.48e-053283410HP:0031409
HumanPhenoAbnormal leukocyte physiology

HYOU1 HLA-DRB1 SMARCAL1 CASP10 SLC46A1 SPPL2A MTHFD1 ALB LRBA HELLS

3.48e-053283410HP:0033796
HumanPhenoAbnormal immunological laboratory finding

HYOU1 HLA-DRB1 SMARCAL1 CASP10 SLC46A1 SPPL2A MTHFD1 ALB LRBA HELLS

7.04e-053563410HP:0003346
HumanPhenoDecreased circulating antibody concentration

HYOU1 SMARCAL1 CASP10 SLC46A1 SPPL2A MTHFD1 LRBA HELLS

8.31e-05224348HP:0004313
HumanPhenoAbnormality of multiple cell lineages in the bone marrow

HLA-DRB1 SMARCAL1 CASP10 SLC46A1 SF3B1 MTHFD1 LRBA

1.47e-04180347HP:0012145
HumanPhenoAbnormal granulocyte morphology

HLA-DRB1 SMARCAL1 CASP10 SLC46A1 SPPL2A SF3B1 MTHFD1 LRBA HELLS

1.64e-04317349HP:0001911
HumanPhenoPancytopenia

HLA-DRB1 SMARCAL1 SLC46A1 SF3B1 MTHFD1 LRBA

1.76e-04129346HP:0001876
HumanPhenoAbnormal lymphocyte count

HYOU1 HLA-DRB1 SMARCAL1 CASP10 SLC46A1 SF3B1 MTHFD1 LRBA HELLS

1.89e-04323349HP:0040088
HumanPhenoCellular metachromasia

HLA-DRB1 SMARCAL1 SLC46A1 SF3B1 MTHFD1 LRBA

1.92e-04131346HP:0003653
HumanPhenoAbnormal cellular immune system morphology

HYOU1 HLA-DRB1 SMARCAL1 CYP27B1 CASP10 SLC46A1 SPPL2A SF3B1 MTHFD1 ALB C5 LRBA C8B HELLS

2.22e-047743414HP:0010987
HumanPhenoAbnormal leukocyte morphology

HYOU1 HLA-DRB1 SMARCAL1 CYP27B1 CASP10 SLC46A1 SPPL2A SF3B1 MTHFD1 ALB C5 LRBA C8B HELLS

2.22e-047743414HP:0001881
HumanPhenoAbnormality of neutrophils

SMARCAL1 CASP10 SLC46A1 SPPL2A SF3B1 MTHFD1 LRBA HELLS

2.97e-04269348HP:0001874
HumanPhenoAbnormal immune system morphology

HYOU1 HLA-DRB1 SMARCAL1 CYP27B1 CASP10 SLC46A1 SPPL2A SF3B1 MTHFD1 ALB C5 LRBA C8B HELLS

3.08e-047983414HP:0032251
HumanPhenoAbnormal myeloid leukocyte morphology

HLA-DRB1 SMARCAL1 CASP10 SLC46A1 SPPL2A SF3B1 MTHFD1 LRBA HELLS

3.18e-04346349HP:0010974
HumanPhenoIncreased circulating globulin level

HLA-DRB1 ALB

4.27e-045342HP:0032311
HumanPhenoIncreased alpha-globulin

HLA-DRB1 ALB

4.27e-045342HP:0005413
HumanPhenoAbnormality of glycosaminoglycan metabolism

HLA-DRB1 SMARCAL1 SLC46A1 SF3B1 MTHFD1 LRBA

4.31e-04152346HP:0004371
HumanPhenoAbnormality of mucopolysaccharide metabolism

HLA-DRB1 SMARCAL1 SLC46A1 SF3B1 MTHFD1 LRBA

4.31e-04152346HP:0011020
HumanPhenoAbnormal circulating polysaccharide concentration

HLA-DRB1 SMARCAL1 SLC46A1 SF3B1 MTHFD1 LRBA

4.31e-04152346HP:0011012
HumanPhenoLymphopenia

HLA-DRB1 SMARCAL1 CASP10 SLC46A1 SF3B1 MTHFD1 LRBA HELLS

4.51e-04286348HP:0001888
HumanPhenoAbnormality of cells of the lymphoid lineage

HLA-DRB1 SMARCAL1 CASP10 SLC46A1 SF3B1 MTHFD1 LRBA HELLS

5.81e-04297348HP:0012140
HumanPhenoDecreased circulating terminal complement component concentration

C5 C8B

6.38e-046342HP:0033057
DomainAtg8

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B2 MAP1LC3B

4.47e-1081155PF02991
DomainAtg8-like

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B2 MAP1LC3B

4.47e-1081155IPR004241
DomainUbiquitin-rel_dom

UBTD2 GABARAP MAP1LC3A GABARAPL1 MAP1LC3B2 OASL MAP1LC3B ARHGAP20

1.84e-051841158IPR029071
DomainIL-1_rcpt_fam

IL1RL2 IL1RAPL1 IL1RAP

3.62e-05111153IPR015621
DomainIg-like_fold

SLAMF8 HLA-DRB1 HLA-DRB4 OBSCN IL1RL2 TGM5 IFNAR1 IL1RAPL1 HMCN1 NTM ROBO1 RIMBP2 IL1RAP TAPBP

1.12e-0470611514IPR013783
Domain-

HLA-DRB1 HLA-DRB4 OBSCN IL1RL2 TGM5 IFNAR1 IL1RAPL1 HMCN1 NTM ROBO1 RIMBP2 IL1RAP TAPBP

2.22e-04663115132.60.40.10
DomainIG_LIKE

SLAMF8 HLA-DRB1 HLA-DRB4 OBSCN IL1RL2 IL1RAPL1 HMCN1 NTM ROBO1 IL1RAP TAPBP

2.25e-0449111511PS50835
DomainIg-like_dom

SLAMF8 HLA-DRB1 HLA-DRB4 OBSCN IL1RL2 IL1RAPL1 HMCN1 NTM ROBO1 IL1RAP TAPBP

2.77e-0450311511IPR007110
DomainTIR

IL1RL2 IL1RAPL1 IL1RAP

2.79e-04211153SM00255
DomainPH_dom-like

RGPD4 RASGRF1 OBSCN APBA2 MTMR6 RGPD3 PLCB1 LRBA ARHGAP20 SNTB2

3.03e-0442611510IPR011993
DomainTIR

IL1RL2 IL1RAPL1 IL1RAP

3.22e-04221153PF01582
Domain-

IL1RL2 IL1RAPL1 IL1RAP

3.68e-042311533.40.50.10140
DomainTIR

IL1RL2 IL1RAPL1 IL1RAP

4.19e-04241153PS50104
DomainTIR_dom

IL1RL2 IL1RAPL1 IL1RAP

4.74e-04251153IPR000157
DomainIL-1_rcpt_I/II-typ

IL1RL2 IL1RAP

5.55e-0461152IPR004074
DomainRab_bind

RGPD4 RGPD3

7.74e-0471152PF16704
DomainGCC2_Rab_bind

RGPD4 RGPD3

7.74e-0471152IPR032023
DomainMHC_II_b_N

HLA-DRB1 HLA-DRB4

1.03e-0381152PD000328
DomainA2M_N_2

A2M C5

1.03e-0381152SM01359
Domain-

A2M C5

1.03e-03811522.60.40.690
DomainA2M_recep

A2M C5

1.03e-0381152SM01361
DomainA2M

A2M C5

1.03e-0381152SM01360
DomainMHC_II_b_N

HLA-DRB1 HLA-DRB4

1.32e-0391152IPR000353
DomainMHC_II_beta

HLA-DRB1 HLA-DRB4

1.32e-0391152SM00921
DomainMHC_II_beta

HLA-DRB1 HLA-DRB4

1.32e-0391152PF00969
DomainA2M

A2M C5

1.64e-03101152PF00207
DomainA2M_N_2

A2M C5

1.64e-03101152IPR011625
DomainA2M_comp

A2M C5

1.64e-03101152IPR011626
DomainA2M_recep

A2M C5

1.64e-03101152PF07677
DomainA2M_comp

A2M C5

1.64e-03101152PF07678
DomainA2M_N

A2M C5

1.64e-03101152PF01835
DomainA2M_N

A2M C5

1.64e-03101152IPR002890
DomainA-macroglobulin_rcpt-bd

A2M C5

1.64e-03101152IPR009048
DomainALPHA_2_MACROGLOBULIN

A2M C5

1.64e-03101152PS00477
DomainA2M_N_2

A2M C5

1.64e-03101152PF07703
DomainMacroglobln_a2

A2M C5

1.64e-03101152IPR001599
Domain-

RGPD4 RGPD3

1.64e-031011521.10.220.60
DomainGrip

RGPD4 RGPD3

1.99e-03111152SM00755
DomainGRIP

RGPD4 RGPD3

1.99e-03111152PF01465
DomainRan_BP1

RGPD4 RGPD3

2.38e-03121152PF00638
DomainRANBD1

RGPD4 RGPD3

2.38e-03121152PS50196
DomainGRIP_dom

RGPD4 RGPD3

2.38e-03121152IPR000237
DomainGRIP

RGPD4 RGPD3

2.38e-03121152PS50913
Domain-

A2M C5

2.38e-031211521.50.10.20
DomainRanBD

RGPD4 RGPD3

2.80e-03131152SM00160
DomainRan_bind_dom

RGPD4 RGPD3

2.80e-03131152IPR000156
DomainMHC_II_a/b_N

HLA-DRB1 HLA-DRB4

3.26e-03141152IPR014745
DomainuDENN

DENND5B DENND5A

3.26e-03141152SM00800
Domain-

HLA-DRB1 HLA-DRB4

3.26e-031411523.10.320.10
DomainuDENN

DENND5B DENND5A

3.74e-03151152PF03456
DomainDENN

DENND5B DENND5A

4.26e-03161152SM00799
DomainDENN

DENND5B DENND5A

4.26e-03161152PF02141
DomaindDENN

DENND5B DENND5A

4.26e-03161152PF03455
DomainUDENN

DENND5B DENND5A

4.26e-03161152PS50946
DomainDDENN

DENND5B DENND5A

4.26e-03161152PS50947
DomaindDENN

DENND5B DENND5A

4.26e-03161152SM00801
DomaindDENN_dom

DENND5B DENND5A

4.26e-03161152IPR005112
DomainuDENN_dom

DENND5B DENND5A

4.26e-03161152IPR005113
DomainDENN

DENND5B DENND5A

4.26e-03161152PS50211
DomainDENN_dom

DENND5B DENND5A

4.26e-03161152IPR001194
DomainHelicase_C

SMARCAL1 RECQL5 DDX54 HELLS

4.33e-031071154PF00271
DomainHELICc

SMARCAL1 RECQL5 DDX54 HELLS

4.33e-031071154SM00490
DomainHelicase_C

SMARCAL1 RECQL5 DDX54 HELLS

4.47e-031081154IPR001650
DomainC1-set

HLA-DRB1 HLA-DRB4 TAPBP

4.49e-03541153PF07654
DomainHELICASE_CTER

SMARCAL1 RECQL5 DDX54 HELLS

4.62e-031091154PS51194
DomainHELICASE_ATP_BIND_1

SMARCAL1 RECQL5 DDX54 HELLS

4.62e-031091154PS51192
DomainDEXDc

SMARCAL1 RECQL5 DDX54 HELLS

4.62e-031091154SM00487
DomainHelicase_ATP-bd

SMARCAL1 RECQL5 DDX54 HELLS

4.77e-031101154IPR014001
DomainRUN

DENND5B DENND5A

5.39e-03181152SM00593
Domainaa-tRNA-synth_I_CS

EPRS1 IARS1

5.39e-03181152IPR001412
DomainTerpenoid_cyclase/PrenylTrfase

A2M C5

5.39e-03181152IPR008930
DomainIg_C1-set

HLA-DRB1 HLA-DRB4 TAPBP

5.49e-03581153IPR003597
DomainRUN

DENND5B DENND5A

6.00e-03191152PS50826
DomainRUN

DENND5B DENND5A

6.00e-03191152PF02759
DomainRun_dom

DENND5B DENND5A

6.00e-03191152IPR004012
DomainAA_TRNA_LIGASE_I

EPRS1 IARS1

6.00e-03191152PS00178
DomainIG_MHC

HLA-DRB1 HLA-DRB4 TAPBP

6.03e-03601153PS00290
PathwayKEGG_MEDICUS_REFERENCE_AUTOPHAGOSOME_AND_LYSOSOME_FUSION_TETHERING_FACTOR_GRASP55

MAP1LC3A MAP1LC3B2 MAP1LC3B

5.66e-066943M47979
PathwayKEGG_MEDICUS_REFERENCE_TBK1_MEDIATED_AUTOPHAGOSOME_FORMATION

MAP1LC3A MAP1LC3B2 MAP1LC3B

3.33e-0510943M47745
PathwayREACTOME_RECEPTOR_MEDIATED_MITOPHAGY

MAP1LC3A MAP1LC3B2 MAP1LC3B

6.05e-0512943MM15525
PathwayKEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_LC3_II_FORMATION

MAP1LC3A MAP1LC3B2 MAP1LC3B

7.82e-0513943M47458
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_P62_TO_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION

MAP1LC3A MAP1LC3B2 MAP1LC3B

7.82e-0513943M47744
PathwayKEGG_MEDICUS_REFERENCE_AUTOPHAGY_VESICLE_NUCLEATION_ELONGATION_MATURATION_SEQUESTOSOME_1_LIKE_RECEPTOR

MAP1LC3A MAP1LC3B2 MAP1LC3B

9.91e-0514943M47975
PathwayWP_8Q1123_RB1CC1_COPY_NUMBER_VARIATION

GABARAP MAP3K5 GABARAPL1

1.51e-0416943M48107
PathwayKEGG_MEDICUS_REFERENCE_AUTOPHAGOSOME_AND_LYSOSOME_FUSION_TETHERING_FACTOR

MAP1LC3A MAP1LC3B2 MAP1LC3B

1.51e-0416943M47978
PathwayKEGG_MEDICUS_REFERENCE_PINK_PARKIN_MEDIATED_AUTOPHAGOSOME_FORMATION

MAP1LC3A MAP1LC3B2 MAP1LC3B

1.82e-0417943M47742
Pubmed

Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B2 MAP1LC3B

2.10e-118116528604719
Pubmed

Autophagy is essential for mouse sense of balance.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B2 MAP1LC3B

2.94e-1012116520577052
Pubmed

Lipidation of the LC3/GABARAP family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3.

GABARAP GABARAPL1 MAP1LC3B2 MAP1LC3B

1.75e-096116424747438
Pubmed

MAPK15/ERK8 stimulates autophagy by interacting with LC3 and GABARAP proteins.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

1.75e-096116422948227
Pubmed

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

1.75e-096116417580304
Pubmed

An ALS-associated variant of the autophagy receptor SQSTM1/p62 reprograms binding selectivity toward the autophagy-related hATG8 proteins.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

4.08e-097116434929165
Pubmed

Autophagy receptor NDP52 regulates pathogen-containing autophagosome maturation.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

8.14e-098116425771791
Pubmed

TRIM32, but not its muscular dystrophy-associated mutant, positively regulates and is targeted to autophagic degradation by p62/SQSTM1.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

8.14e-098116431685529
Pubmed

Mass spectrometry proteomics reveals a function for mammalian CALCOCO1 in MTOR-regulated selective autophagy.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

8.14e-098116431971854
Pubmed

DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

8.14e-098116422470510
Pubmed

Regulation of endoplasmic reticulum turnover by selective autophagy.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

1.46e-089116426040720
Pubmed

Autophagy mediates degradation of nuclear lamina.

GABARAP MAP1LC3A MAP1LC3B2 MAP1LC3B

1.46e-089116426524528
Pubmed

Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

1.46e-089116429867141
Pubmed

Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

1.46e-089116421617041
Pubmed

The E3 ubiquitin ligase NEDD4 enhances killing of membrane-perturbing intracellular bacteria by promoting autophagy.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

1.46e-089116429251248
Pubmed

Nix is a selective autophagy receptor for mitochondrial clearance.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

2.43e-0810116420010802
Pubmed

A role for NBR1 in autophagosomal degradation of ubiquitinated substrates.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

2.43e-0810116419250911
Pubmed

The IAP family member BRUCE regulates autophagosome-lysosome fusion.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

2.43e-0810116429426817
Pubmed

HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

2.43e-0810116430217973
Pubmed

ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

2.43e-0810116428287329
Pubmed

ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.

EPRS1 HACD3 IARS1 ATG2B MTHFD1 DDX54 GCN1 TAPBP TOP2B AHNAK2

2.49e-082681161033024031
Pubmed

Network organization of the human autophagy system.

HACD3 USP11 ATG2B POLRMT GABARAP MAP1LC3A NEK9 MAP3K5 RIF1 GABARAPL1 MAP1LC3B GCN1

2.82e-084371161220562859
Pubmed

Developmental expression of LC3alpha and beta: absence of fibronectin or autophagy phenotype in LC3beta knockout mice.

MAP1LC3A MAP1LC3B2 MAP1LC3B

3.62e-083116318069693
Pubmed

Arginine68 is an essential residue for the C-terminal cleavage of human Atg8 family proteins.

GABARAP GABARAPL1 MAP1LC3B

3.62e-083116323721406
Pubmed

Microtubule-Associated Protein 1 Light Chain 3 (LC3) Isoforms in RPE and Retina.

MAP1LC3A MAP1LC3B2 MAP1LC3B

3.62e-083116329721994
Pubmed

The DNA methyltransferase DNMT3A contributes to autophagy long-term memory.

GABARAP GABARAPL1 MAP1LC3B2 MAP1LC3B

3.81e-0811116432876528
Pubmed

ATG8 family proteins act as scaffolds for assembly of the ULK complex: sequence requirements for LC3-interacting region (LIR) motifs.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

3.81e-0811116423043107
Pubmed

Methods for Studying Interactions Between Atg8/LC3/GABARAP and LIR-Containing Proteins.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

3.81e-0811116428253953
Pubmed

Multiple roles of integrin-α3 at the neuromuscular junction.

MAP1LC3A MAP1LC3B2 MAP1LC3B BSN

5.70e-0812116428386022
Pubmed

NIMA-related kinase 9-mediated phosphorylation of the microtubule-associated LC3B protein at Thr-50 suppresses selective autophagy of p62/sequestosome 1.

GABARAP NEK9 GABARAPL1 MAP1LC3B

1.15e-0714116431857374
Pubmed

The Hedgehog signalling pathway regulates autophagy.

MAP1LC3A MAP1LC3B2 MAP1LC3B

1.44e-074116323149744
Pubmed

Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells.

GABARAP MAP1LC3A MAP1LC3B

1.44e-074116322267086
Pubmed

The Contribution of Melanoregulin to Microtubule-Associated Protein 1 Light Chain 3 (LC3) Associated Phagocytosis in Retinal Pigment Epithelium.

MAP1LC3A MAP1LC3B2 MAP1LC3B

1.44e-074116325301234
Pubmed

Acetylation modulates LC3 stability and cargo recognition.

MAP1LC3A MAP1LC3B2 MAP1LC3B

1.44e-074116330633346
Pubmed

Autophagic compartments gain access to the MHC class II compartments in thymic epithelium.

MAP1LC3A MAP1LC3B2 MAP1LC3B

1.44e-074116319915056
Pubmed

CCT2 is an aggrephagy receptor for clearance of solid protein aggregates.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

1.56e-0715116435366418
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

OR51A4 EPRS1 HACD3 IARS1 NEXMIF OBSCN MTHFD1 ABCE1 CSNK1G2 EIF4E PRICKLE2 ALB ARHGAP20 PLS1

1.77e-077361161429676528
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

RGPD4 EPRS1 HACD3 IARS1 ATG2B APBA2 CPZ SORBS1 PDXK SF3B1 MTHFD1 ABCE1 RGPD3 PRICKLE2 PLCB1 BSN GCN1

2.47e-0711391161736417873
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

EPRS1 HYOU1 HACD3 IARS1 POLRMT NEK9 PDXK SLC38A1 RIF1 SF3B1 MTHFD1 ABCE1 EIF4E DDX54 BSN GCN1 IQGAP3 TOP2B HELLS

2.55e-0714251161930948266
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

A2M EPRS1 HYOU1 LONP2 POLRMT FBRSL1 TUBGCP4 ZC3H4 ABCE1 AACS DENND5A IQGAP3 HELLS

2.85e-076501161338777146
Pubmed

Intrinsically Disordered Protein TEX264 Mediates ER-phagy.

GABARAP MAP1LC3A GABARAPL1 MTHFD1 ABCE1 LRBA MAP1LC3B

3.03e-07131116731006538
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

TDRD15 AK8 PPL SLC38A1 RIF1 FAT1 SF3B1 MTHFD1 ZC3H4 ROBO1 ALB LRBA GCN1 HELLS

3.40e-077771161435844135
Pubmed

Autophagy-related gene Atg5 is essential for astrocyte differentiation in the developing mouse cortex.

MAP1LC3A MAP1LC3B2 MAP1LC3B

3.60e-075116325227738
Pubmed

TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

4.38e-0719116426347139
Pubmed

TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

5.46e-0720116425127057
Pubmed

Nix, a receptor protein for mitophagy in mammals.

GABARAP GABARAPL1 MAP1LC3B

7.18e-076116320200478
Pubmed

HYPK coordinates degradation of polyneddylated proteins by autophagy.

MAP1LC3A GABARAPL1 MAP1LC3B

7.18e-076116334836490
Pubmed

Autophagy appears during the development of the mouse lower first molar.

MAP1LC3A MAP1LC3B2 MAP1LC3B

7.18e-076116323052835
Pubmed

OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation.

GABARAP MAP1LC3B2 MAP1LC3B

7.18e-076116321383079
Pubmed

A DNM2 Centronuclear Myopathy Mutation Reveals a Link between Recycling Endosome Scission and Autophagy.

GABARAP GABARAPL1 MAP1LC3B

7.18e-076116332315611
Pubmed

Phosphatidylserine in addition to phosphatidylethanolamine is an in vitro target of the mammalian Atg8 modifiers, LC3, GABARAP, and GATE-16.

GABARAP MAP1LC3A MAP1LC3B

7.18e-076116316303767
Pubmed

Autophagy proteins regulate the secretory component of osteoclastic bone resorption.

MAP1LC3A MAP1LC3B2 MAP1LC3B

7.18e-076116322055344
Pubmed

Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.

HACD3 USP11 IARS1 SF3B1 MTHFD1 ZC3H4 ABCE1 DDX54 PHF10 IQGAP3 MOV10

7.46e-074861161130940648
Pubmed

SAMM50 acts with p62 in piecemeal basal- and OXPHOS-induced mitophagy of SAM and MICOS components.

GABARAP MAP1LC3A MAP1LC3B2 MAP1LC3B

8.20e-0722116434037656
Pubmed

Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes.

MAP1LC3A MAP1LC3B2 MAP1LC3B MAPK8

1.19e-0624116422854957
Pubmed

Involvement of the c-jun N-terminal kinases JNK1 and JNK2 in complement-mediated cell death.

C5 C8B MAPK8

1.25e-067116319864026
Pubmed

The mouse APG10 homologue, an E2-like enzyme for Apg12p conjugation, facilitates MAP-LC3 modification.

MAP1LC3A MAP1LC3B2 MAP1LC3B

1.25e-067116312890687
Pubmed

Structural determinants in GABARAP required for the selective binding and recruitment of ALFY to LC3B-positive structures.

GABARAP GABARAPL1 MAP1LC3B

1.25e-067116324668264
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

EPRS1 HYOU1 HACD3 IARS1 NEK9 RIF1 SF3B1 MTHFD1 LRBA GCN1 TOP2B HELLS

1.59e-066381161233239621
Pubmed

Defining the membrane proteome of NK cells.

EPRS1 HYOU1 LONP2 IARS1 HLA-DRB1 ST3GAL1 TUBGCP4 ITGAX MTHFD1 ABCE1 CSNK1G2 DDX54 OASL LRBA IL1RAP GCN1

1.76e-0611681161619946888
Pubmed

Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers.

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B

1.94e-0627116422354992
Pubmed

Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.

GABARAP MAP1LC3A SF3B1 TC2N GABARAPL1 MAP1LC3B

1.95e-06110116637219487
Pubmed

Phosphorylation of NBR1 by GSK3 modulates protein aggregation.

GABARAP MAP1LC3B2 MAP1LC3B

2.00e-068116324879152
Pubmed

Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism.

GABARAP MAP1LC3A MAP1LC3B

2.00e-068116324290141
Pubmed

RIPOR2-mediated autophagy dysfunction is critical for aminoglycoside-induced hearing loss.

GABARAP MAP1LC3B2 MAP1LC3B

2.00e-068116336113482
Pubmed

Autophagy proteins suppress protective type I interferon signalling in response to the murine gut microbiota.

IFNAR1 MAP1LC3B2 MAP1LC3B

2.00e-068116330202015
Pubmed

Murine Apg12p has a substrate preference for murine Apg7p over three Apg8p homologs.

GABARAP MAP1LC3B2 MAP1LC3B

2.00e-068116311890701
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

EPRS1 USP11 IARS1 FRYL NEK9 RIF1 SF3B1 MTHFD1 ZC3H4 ALB MOV10

2.51e-065511161134728620
Pubmed

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.

RGPD4 RGPD3 TOP2B

2.99e-069116318394993
Pubmed

Ambra1 regulates autophagy and development of the nervous system.

MAP1LC3A MAP1LC3B2 MAP1LC3B

2.99e-069116317589504
Pubmed

Developmental regulation of MURF ubiquitin ligases and autophagy proteins nbr1, p62/SQSTM1 and LC3 during cardiac myofibril assembly and turnover.

MAP1LC3A MAP1LC3B2 MAP1LC3B

2.99e-069116321185285
Pubmed

The autophagy-inducing kinases, ULK1 and ULK2, regulate axon guidance in the developing mouse forebrain via a noncanonical pathway.

MAP1LC3A MAP1LC3B2 ROBO1 MAP1LC3B

3.45e-0631116429099309
Pubmed

SIP/CacyBP promotes autophagy by regulating levels of BRUCE/Apollon, which stimulates LC3-I degradation.

GABARAP GABARAPL1 MAP1LC3B

4.26e-0610116331213539
Pubmed

Cdx2 regulates endo-lysosomal function and epithelial cell polarity.

MAP1LC3A MAP1LC3B2 MAP1LC3B PLS1

4.46e-0633116420551175
Pubmed

Augmented BMP signaling commits cranial neural crest cells to a chondrogenic fate by suppressing autophagic β-catenin degradation.

MAP1LC3A MAP1LC3B2 MAP1LC3B MAPK8

4.46e-0633116433436499
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

EPRS1 HYOU1 HACD3 IARS1 ICE2 ATG2B SLC38A1 MTHFD1 ABCE1 ROBO1 LRBA GCN1

4.61e-067081161239231216
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

EPRS1 HACD3 FRYL ZC3H4 GCN1 IQGAP3 TOP2B

5.49e-06202116733005030
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

RGPD4 EPRS1 HACD3 IARS1 SF3B1 GCN1 IQGAP3

5.49e-06202116724639526
Pubmed

Global Proximity Interactome of the Human Macroautophagy Pathway.

ATG2B MAP1LC3A GABARAPL1 MAP1LC3B

5.68e-0635116434524948
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

HYOU1 DIS3L IARS1 ICE2 ZC3H4 EIF4E GCN1 PHF10 TOP2B MOV10 AHNAK2 HELLS

5.78e-067241161236232890
Pubmed

Pacer Is a Mediator of mTORC1 and GSK3-TIP60 Signaling in Regulation of Autophagosome Maturation and Lipid Metabolism.

MAP1LC3A MAP1LC3B2 MAP1LC3B

5.85e-0611116330704899
Pubmed

Essential Roles of L-Type Amino Acid Transporter 1 in Syncytiotrophoblast Development by Presenting Fusogenic 4F2hc.

MAP1LC3A MAP1LC3B2 MAP1LC3B

5.85e-0611116328320871
Pubmed

Functional interaction between autophagy and ciliogenesis.

GABARAP MAP1LC3B2 MAP1LC3B

5.85e-0611116324089209
Pubmed

CUL3-KBTBD6/KBTBD7 ubiquitin ligase cooperates with GABARAP proteins to spatially restrict TIAM1-RAC1 signaling.

GABARAP GABARAPL1 MAP1LC3B

5.85e-0611116325684205
Pubmed

Intracellular overexpression of HIV-1 Nef impairs differentiation and maturation of monocytic precursors towards dendritic cells.

HLA-DRB1 HLA-DRB4 ITGAX

5.85e-0611116322808111
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

EPRS1 HYOU1 HACD3 USP11 IARS1 GABARAP FRYL SORBS1 NEK9 SF3B1 MTHFD1 EIF4E LRBA GCN1 MOV10 HELLS

5.86e-0612841161617353931
Pubmed

Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.

EPRS1 HACD3 LONP2 IARS1 SMARCAL1 SF3B1 MTHFD1 ALB GCN1

5.86e-06383116929331416
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

OBSCN POLRMT SORBS1 TGM5 MTHFD1 ZC3H4 DDX54 LRBA TAPBP HELLS

6.85e-064971161036774506
Pubmed

Embryogenesis and Adult Life in the Absence of Intrinsic Apoptosis Effectors BAX, BAK, and BOK.

MAP1LC3A MAP1LC3B2 MAP1LC3B

7.78e-0612116329775594
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

EPRS1 HYOU1 HACD3 IARS1 RIF1 SF3B1 RRP36 MTHFD1 ZC3H4 DDX54 ALB GCN1 TOP2B HELLS

8.41e-0610241161424711643
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

EPRS1 HYOU1 HACD3 USP11 IARS1 ICE2 APBA2 POLRMT SF3B1 MTHFD1 EIF4E ARHGAP20 PHF10 PLS1 SNTB2 MOV10

9.53e-0613351161629229926
Pubmed

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.

EPRS1 IARS1 POLRMT RIF1 SF3B1 GCN1 TOP2B

9.86e-06221116729991511
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

SMARCAL1 FBRSL1 SLC38A1 IL1RAPL1 ABCE1 PLCB1 C5 BSN SNTB2 AHNAK2 HELLS

1.00e-056381161131182584
Pubmed

The HIV proteins Tat and Nef promote human bone marrow mesenchymal stem cell senescence and alter osteoblastic differentiation.

GABARAP MAP1LC3A MAP1LC3B

1.01e-0513116325847297
Pubmed

Apoptosis signal-regulating kinase (ASK)-1 mediates apoptosis through activation of JNK1 following engagement of membrane immunoglobulin.

MAP3K5 MAPK8

1.10e-052116219766627
Pubmed

Two distinct subtypes of the HLA-DRw12 haplotypes in the Japanese population detected by nucleotide sequence analysis and oligonucleotide genotyping.

HLA-DRB1 HLA-DRB4

1.10e-05211622592019
Pubmed

ER stress and ASK1-JNK activation contribute to oridonin-induced apoptosis and growth inhibition in cultured human hepatoblastoma HuH-6 cells.

MAP3K5 MAPK8

1.10e-052116223580093
Pubmed

Nutrient starvation affects expression of LC3 family at the feto-maternal interface during murine placentation.

MAP1LC3B2 MAP1LC3B

1.10e-052116225421500
Pubmed

Development of LC3/GABARAP sensors containing a LIR and a hydrophobic domain to monitor autophagy.

GABARAP MAP1LC3A

1.10e-052116228320742
Pubmed

Structural comparison of the genes of two HLA-DR supertypic groups: the loci encoding DRw52 and DRw53 are not truly allelic.

HLA-DRB1 HLA-DRB4

1.10e-05211623596674
InteractionRNF123 interactions

OR51A4 EPRS1 HACD3 IARS1 NEXMIF OBSCN GABARAP GABARAPL1 MTHFD1 ABCE1 CSNK1G2 EIF4E PRICKLE2 ALB MAP1LC3B ARHGAP20 PLS1 MOV10

1.10e-0682411618int:RNF123
InteractionLRP8 interactions

USP11 APBA2 APOH ALB MAPK8 MOV10

1.03e-05861166int:LRP8
InteractionATG4B interactions

GABARAP MAP1LC3A GABARAPL1 MAP1LC3B2 EIF4E MAP1LC3B MOV10

1.25e-051341167int:ATG4B
InteractionANK2 interactions

OBSCN GABARAP MAP1LC3A GABARAPL1 ABCE1 MAP1LC3B

2.18e-05981166int:ANK2
InteractionPINK1 interactions

A2M EPRS1 HYOU1 IARS1 MAP1LC3A APOH PPL SF3B1 MTHFD1 ALB MAP1LC3B GCN1 MOV10 AHNAK2

3.61e-0567911614int:PINK1
CytobandEnsembl 112 genes in cytogenetic band chr12q24

FBRSL1 MAP1LC3B2 DDX54 OASL AACS RIMBP2 GCN1

9.38e-054151167chr12q24
Cytoband3p24

KAT2B TOP2B

1.75e-04811623p24
Cytoband12q24.2

OASL GCN1

7.42e-0416116212q24.2
CytobandEnsembl 112 genes in cytogenetic band chr2q12

RGPD4 IL1RL2 RGPD3

1.20e-03821163chr2q12
Cytoband12p11.21

DENND5B OVOS2

1.41e-0322116212p11.21
CytobandEnsembl 112 genes in cytogenetic band chr2q33

CASP10 COQ10B SF3B1 CARF

1.87e-032051164chr2q33
Cytoband15q22.2

HACD3 ICE2

2.46e-0329116215q22.2
GeneFamilyAutophagy related

ATG2B GABARAP MAP1LC3A GABARAPL1 MAP1LC3B2 MAP1LC3B

9.70e-09338661022
GeneFamilyCD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing

IL1RL2 IL1RAPL1 IL1RAP

4.54e-05158631296
GeneFamilyTopoisomerases

TOP1MT TOP2B

3.31e-0468621050
GeneFamilyComplement system|Sushi domain containing

ITGAX C5 C8B

6.62e-0436863492
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

A2M C5

7.88e-0498621234
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

OBSCN IL1RAPL1 HMCN1 NTM ROBO1

1.03e-03161865593
GeneFamilyC1-set domain containing

HLA-DRB1 HLA-DRB4 TAPBP

1.04e-0342863591
GeneFamilyCD molecules|I-set domain containing|Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing

IL1RL2 IL1RAPL1 IL1RAP

1.04e-0342863602
GeneFamilyAminoacyl tRNA synthetases, Class I

EPRS1 IARS1

3.63e-0319862131
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

DENND5B DENND5A

6.25e-0325862504
CoexpressionMITSIADES_RESPONSE_TO_APLIDIN_DN

EPRS1 RAP2A PDXK SLC38A1 KAT2B SF3B1 GCN1 HELLS

1.50e-052501158M11318
CoexpressionGSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN

DENND5B HACD3 ABCE1 NTM FGF13 DENND5A SNTB2

2.96e-052001157M3469
CoexpressionGSE2585_AIRE_KO_VS_WT_CD80_LOW_MTEC_DN

A2M SLC46A1 PDXK GPR83 GABARAPL1 OASL IQGAP3

2.96e-052001157M6270
CoexpressionGSE25123_WT_VS_PPARG_KO_MACROPHAGE_ROSIGLITAZONE_STIM_UP

A2M DENND5B PDE9A RASGRF1 HACD3 CASP10 MAP3K5

2.96e-052001157M7978
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPPL2A HMCN1 CLCNKB PRICKLE2 PLCB1 RIMBP2 FGF13 LRBA

3.37e-081891158f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

A2M EPRS1 FRYL TUBGCP4 SLC38A1 LRBA HELLS

5.34e-071851157a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

A2M EPRS1 FRYL TUBGCP4 SLC38A1 LRBA HELLS

5.54e-0718611578571956890fc9894d766ba294a28e376b4aba428
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B-Memory_B_cells|GI_small-bowel / Manually curated celltypes from each tissue

DENND5B RASGRF1 NEXMIF HLA-DRB1 KHDRBS2 CNR1

4.98e-0616811568e025bb0541746e232b77ac0e31412ae71420c47
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B|GI_small-bowel / Manually curated celltypes from each tissue

DENND5B RASGRF1 NEXMIF HLA-DRB1 KHDRBS2 CNR1

4.98e-0616811565535c1b8b7fde7b59a1bc0580cebdfa963aa1c39
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASGRF1 NEXMIF RIF1 TC2N IQGAP3 HELLS

4.98e-06168115608f6e171a1ea5cf65149744296d0fcd6c7b9684e
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNB2 SORBS1 FAT1 HMCN1 PLCB1 CDH6

6.09e-061741156015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCellnormal_Lung-Fibroblasts-Pericytes|normal_Lung / Location, Cell class and cell subclass

A2M OBSCN MAP1LC3A FAT1 NSG2 CDH6

7.63e-061811156f74941e49950027360d71ea3b205fc20c6929766
ToppCell3'_v3-blood-Lymphocytic_B-Memory_B_cells|blood / Manually curated celltypes from each tissue

DENND5B TDRD15 RASGRF1 HLA-DRB1 AK8 PRICKLE2

8.13e-061831156e3a418b745d7f040adf47be9e1043b945cae47ed
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

A2M CACNB2 COL6A5 HMCN1 ROBO1 ARHGAP20

9.19e-061871156e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB2 HMCN1 CLCNKB PRICKLE2 PLCB1 RIMBP2

9.48e-0618811563cee9916399e2e7580cecbcbb27424a71e7e7ac0
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNB2 COL6A5 CPZ CYP39A1 NTM ARHGAP20

9.77e-061891156a153b83314cf52808f685296cff8c95af3f4983d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

OVOS2 FAT1 ROBO1 RIMBP2 FGF13 CNR1

9.77e-061891156f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 TC2N CLCNKB ALB PLS1 IQGAP3

9.77e-061891156c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

CACNB2 OBSCN SORBS1 SLC38A1 IL1RAPL1 FAT1

1.01e-05190115693c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNB2 COL6A5 MAP3K5 NTM ROBO1 ARHGAP20

1.01e-05190115645df8fee00f8949937863159d7aa042e72748d9b
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ACR KHDRBS2 OBSCN SORBS1 IL1RAPL1 PRICKLE2

1.01e-0519011560a351609a72fd638c84b2435782e312ee6a33aac
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

A2M HYOU1 FRYL SLC38A1 LRBA HELLS

1.04e-0519111569454f642c3621370fa23640b631301346b300950
ToppCellCOVID-19-kidney-TAL|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE9A NEXMIF CLCNKB PLCB1 RIMBP2 FGF13

1.04e-051911156fe55475ce0666ab5122447a813dc2369e24947b8
ToppCellMesenchymal-vascular_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

CACNB2 SORBS1 FAT1 HMCN1 PLCB1 CDH6

1.04e-051911156fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCellCOVID-19-kidney-Mito-rich_Distal|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE9A NEXMIF CLCNKB PLCB1 RIMBP2 FGF13

1.04e-0519111560965f621ebcd92ccdeb21cc27022180ce3cfe910
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNB2 COL6A5 CYP39A1 NTM ROBO1 ARHGAP20

1.07e-0519211566f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNB2 COL6A5 CPZ CYP39A1 NTM ARHGAP20

1.07e-051921156dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

A2M CACNB2 IL1RAPL1 HMCN1 PRICKLE2 ROBO1

1.10e-051931156e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNB2 COL6A5 CYP39A1 NTM ROBO1 ARHGAP20

1.10e-051931156fb28717fadd06c3840636d25409ce80c9254bd34
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNB2 COL6A5 CYP39A1 NTM ROBO1 ARHGAP20

1.13e-05194115660622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KHDRBS2 PPL SLC38A1 TC2N C5 PLS1

1.17e-051951156d67a2b489c29bfd575751c13d2a5b1efdec5240a
ToppCellPCW_10-12-Epithelial|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KHDRBS2 PPL SLC38A1 TC2N RIMBP2 PLS1

1.20e-0519611569bfb31ff3e4f2c0a9405c418c86bfec5dbca23e2
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

APBA2 ITGAX GABARAPL1 MAP1LC3B2 DENND5A MAP1LC3B

1.20e-051961156ff88e5b919b1be93159ad2200a7786d1c5272724
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

A2M CACNB2 COL6A5 HMCN1 ROBO1 ARHGAP20

1.27e-0519811563ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-CD4+_CTL|Int-URO / Disease, condition lineage and cell class

A2M UBTD2 TC2N CARF PLCB1 PLS1

1.27e-051981156717735d755745439f97ba1b71785c73945dfa9c5
ToppCellStriatum-Neuronal|Striatum / BrainAtlas - Mouse McCarroll V32

RASGRF1 GABARAPL1 NSG2 PLCB1 RIMBP2 BSN

1.35e-052001156c888fd487990cad482a4ca47601cdebc0ca3f3ce
ToppCellmetastatic_Lymph_Node-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

HLA-DRB1 CYP27B1 OVOS2 MAP1LC3A IFNAR1

3.39e-0514211550e0f8bb956ff89dc98e8fa56f8acac33e01a26dd
ToppCellLPS-antiTNF-Endothelial-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND5B TUBGCP4 NEK9 CLCNKB PLS1

3.62e-05144115575b16adfbe84f69376e6566d531ba7919d5c5192
ToppCell(02)_Cycling_Basal_(regeneration)-(2)_48hpi|(02)_Cycling_Basal_(regeneration) / shred by cell type and Timepoint

EPRS1 GABARAP MAP1LC3A MAP1LC3B MOV10

4.13e-051481155a061a745c09254e063411b7d835d5597a0007e29
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

OBSCN APBA2 SLC38A1 TC2N LRBA

4.54e-051511155999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAT1 RIMBP2 FGF13 IL1RAP CNR1

4.69e-051521155fed80b467ec9e30c7f98bed6cc4f8c583b715e9e
ToppCellInt-URO-Lymphocyte-T_NK-CD4_CTL|Int-URO / Disease, Lineage and Cell Type

A2M TC2N CARF PLCB1 PLS1

4.84e-051531155fdc7dfa8f4db90bfdc7180bf178cf6d2dd064d97
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DAPL1 FAT1 NTM ROBO1 CDH6

5.30e-051561155dd41ed918b07fa248da458a629b3c53cb7ea8764
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DAPL1 FAT1 NTM ROBO1 CDH6

5.30e-051561155abf9dd075b1ca8f613c660cc82f8a5af071fb6ab
ToppCelllymphoid-T_cell-pro-T_cell|T_cell / Lineage, cell class and subclass

DENND5B HLA-DRB1 ITGAX OASL IQGAP3

5.98e-05160115566fe86d2f37983761141e5bb3de127f0b4bb0951
ToppCellBasal_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

NEXMIF KHDRBS2 IL1RL2 ROBO1 FGF13

6.72e-051641155b15a26130a1ea1b370b6e3be21f02a0d6aaf6b3c
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

RASGRF1 IL1RL2 NSG2 ROBO1 IL1RAP

6.92e-0516511559795ce31689bc63f5a2d68725ef00b23a90c3846
ToppCellmild_COVID-19_(asymptomatic)-Plasmablast|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

DENND5B PPL PRICKLE2 ROBO1 PLS1

7.12e-0516611550cc3b9681bc000a1b00d3b60f79f16eea1c2e2e1
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

ACR KHDRBS2 OBSCN SORBS1 PRICKLE2

7.33e-0516711555af9127bae05768a5164d5708a4ad37edca99324
ToppCellmild_COVID-19_(asymptomatic)-Plasmablast|World / disease group, cell group and cell class (v2)

DENND5B PPL PRICKLE2 ROBO1 PLS1

7.33e-051671155f26ae4de4804a3486502e3df37eabf3dfca688f5
ToppCellCOVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type

SORBS1 IL1RAPL1 NTM PLCB1 IL1RAP

7.53e-05168115588c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell10x5'v1-week_12-13-Myeloid_DC-DC-DC1|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SLAMF8 HLA-DRB1 SLC46A1 TGM5 ARHGAP20

7.75e-051691155319511ea57bbd72c2d95e8516d093689df67a912
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE9A DAPL1 CPZ FAT1 CDH6

7.97e-051701155ce2fd2fbbfd152290be0cf8e513f102fdc182b41
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE9A DAPL1 CPZ FAT1 CDH6

7.97e-051701155ab5c6a91c371e4df15b0842828dc55039695ab06
ToppCellCOVID-19-kidney-Bcells|COVID-19 / Disease (COVID-19 only), tissue and cell type

DENND5B TDRD15 NEXMIF KHDRBS2 SLC38A1

8.19e-0517111558e8fb79968b1a5c34d1d9cad7f9155fabfdb7cc7
ToppCelldroplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLAMF8 FBRSL1 TUBGCP4 ITGAX IQGAP3

8.42e-051721155b043d4f81dced7fb3326043f68474123be47cc5d
ToppCellAdult-Mesenchymal-pericyte_cell-D175|Adult / Lineage, Cell type, age group and donor

A2M OBSCN COL6A5 PLCB1 CDH6

8.65e-051731155fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Myeloid-cDC1|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLAMF8 HLA-DRB1 ITGAX TGM5 ARHGAP20

8.65e-051731155d13ae4046a25ee0fb492ddedf44583a879a432e9
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

SORBS1 HMCN1 PLCB1 CDH6 CNR1

8.65e-0517311555416b092321c7d9b63f0418c60f2402a138355bf
ToppCellCOVID-19-kidney-PCT-S3-2|kidney / Disease (COVID-19 only), tissue and cell type

TDRD15 APOH ALB C5 C8B

8.89e-0517411555aa2fb631505600f37d2b87b02def7be139dc262
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPPL2A GABARAPL1 HMCN1 CLCNKB FGF13

9.13e-051751155787ac1a12cda10af5c8830471702a4cbaf43e79e
ToppCellCOVID-19-kidney-PCT-S3-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

TDRD15 APOH ALB C5 C8B

9.38e-051761155b6497324e3e52f514ce556a3fa0c3011c45dcc7b
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-cDC1|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLAMF8 HLA-DRB1 ITGAX ROBO1 ARHGAP20

9.63e-051771155345cebc19f93970a9a46be139208b300081f5493
ToppCellNS-moderate-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PDE9A HACD3 SORBS1 CLCNKB RIMBP2

9.63e-05177115599500aed584f793aaf308f8afbf5d1c6a9b4ee55
ToppCell10x3'2.3-week_12-13-Myeloid_macrophage-stroma-erythroid_macrophage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

IL1RAPL1 RECQL5 FGF13 ARHGAP20 CDH6

1.02e-041791155c17ae394b855f01f8ca1765c416fd8b34a96e60b
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

CACNB2 SORBS1 MAP3K5 FAT1 CDH6

1.02e-041791155a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCellwk_15-18-Epithelial-PNS-KCNIP4+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NEXMIF NSG2 RIMBP2 BSN CNR1

1.02e-041791155e20bfdfb6d5af8556eb66b81a19fbe4e3e28334a
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M COL6A5 AK8 TC2N CCDC33

1.04e-041801155729f0d7af573c7796d8e28e6eec3af2fc0bd33a2
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M COL6A5 AK8 TC2N CCDC33

1.04e-0418011559ef79a7c60227e352ac166c7274adb31f585f5ca
ToppCellRV|World / Chamber and Cluster_Paper

CACNB2 OBSCN ST3GAL1 SORBS1 IL1RAPL1

1.07e-041811155bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DAPL1 FAT1 NTM ROBO1 IL1RAP

1.07e-0418111555f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M CACNB2 COL6A5 HMCN1 ROBO1

1.07e-0418111559ede19228ba5c0668a9c06c915510b95585216ef
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DAPL1 FAT1 NTM ROBO1 IL1RAP

1.07e-041811155c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PPL HMCN1 PLCB1 RIMBP2 FGF13

1.10e-041821155a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GABARAPL1 HMCN1 CLCNKB FGF13 LRBA

1.10e-0418211555f513bbb7125956eb528e3120de3fd776770a7c3
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175|Adult / Lineage, Cell type, age group and donor

KHDRBS2 SORBS1 IL1RAPL1 PRICKLE2 ARC

1.10e-0418211558b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCellLA-11._Adipocyte|LA / Chamber and Cluster_Paper

PDXK NTM AACS FGF13 ARHGAP20

1.13e-0418311553f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M OBSCN FAT1 HMCN1 ROBO1

1.16e-0418411552cbed6462fea2622871bb7e49b0df3d984239281
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NSG2 RIMBP2 FGF13 CDH6 CNR1

1.16e-041841155abb61e744a9031e0c91eb560a8f486a0ca5a01cc
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB2 HMCN1 PRICKLE2 PLCB1 LRBA

1.16e-041841155e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M OBSCN FAT1 HMCN1 ROBO1

1.16e-041841155ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M OBSCN FAT1 HMCN1 ROBO1

1.16e-0418411552b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCV-Healthy-7|Healthy / Virus stimulation, Condition and Cluster

HACD3 TUBGCP4 CARF IL1RAP HELLS

1.19e-0418511551979d189c204f4c2893e3170a514ee7d5523406c
ToppCellControl-T_cells-CD8+_T_cells|Control / group, cell type (main and fine annotations)

A2M APBA2 SLC38A1 KAT2B PLCB1

1.19e-04185115502ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCell3'_v3-blood-Lymphocytic_B|blood / Manually curated celltypes from each tissue

DENND5B RASGRF1 HLA-DRB1 KHDRBS2 AK8

1.22e-0418611555624b1fc7eab9f505588fcc86a24d14f8bcbfef7
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

A2M OBSCN FAT1 PLCB1 CDH6

1.22e-041861155888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KHDRBS2 FAT1 PRICKLE2 CDH6 PLS1

1.22e-041861155f28d72b47624b69a580b4429e2be560a26898591
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 ROBO1 RIMBP2 FGF13 CNR1

1.22e-041861155310d16f4e5cffee3ea6d7635508c513a3b92131e
ToppCell3'-Adult-LargeIntestine-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLAMF8 RASGRF1 HLA-DRB1 ITGAX CNR1

1.25e-041871155d69f4eee0304a7db226275ab77fc9d5d2b6f3a07
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB2 CLCNKB PRICKLE2 PLCB1 RIMBP2

1.25e-0418711557ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PPL HMCN1 PLCB1 RIMBP2 FGF13

1.25e-04187115577886f99c229610abd28c4c370d2c7d1536c9782
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M FRYL SORBS1 PRICKLE2 PLCB1

1.28e-041881155117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRF1 ITGAX SLC38A1 NTM CNR1

1.28e-0418811551efbc99bcd6542e5d9fa91edb7c4295167914786
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPPL2A HMCN1 CLCNKB FGF13 LRBA

1.28e-041881155bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPPL2A HMCN1 CLCNKB FGF13 LRBA

1.28e-041881155eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Adult / Lineage, Cell type, age group and donor

KHDRBS2 OBSCN SORBS1 IL1RAPL1 PRICKLE2

1.28e-041881155e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCellCOVID-19-kidney-DCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDE9A NEXMIF CLCNKB RIMBP2 FGF13

1.28e-0418811551d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HLA-DRB1 OASL DENND5A C8B IL1RAP

1.31e-041891155a59025e82fabd9d60e2438dee85b2644478cc7c8
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNB2 COL6A5 CPZ NTM ARHGAP20

1.31e-041891155e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPL PRICKLE2 PLCB1 RIMBP2 FGF13

1.31e-041891155aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPL PRICKLE2 PLCB1 RIMBP2 FGF13

1.31e-0418911558977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCellAdult|World / Lineage, Cell type, age group and donor

RASGRF1 ST3GAL1 ITGAX NTM CNR1

1.31e-0418911555cd285bfad973125d46d704fec18b21266a63379
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

CACNB2 OBSCN SORBS1 SLC38A1 IL1RAPL1

1.31e-0418911550a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PPL SLC38A1 TC2N RIMBP2 PLS1

1.34e-041901155c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
DiseaseC5a anaphylatoxin measurement

APOH C5

4.27e-0531122EFO_0020208
DiseaseBipolar Disorder

CACNB2 PDE9A RASGRF1 HLA-DRB1 HLA-DRB4 ST3GAL1 MTHFD1 PLCB1 CNR1

8.82e-054771129C0005586
DiseaseSchizophrenia

CACNB2 HLA-DRB1 APBA2 GABARAP ST3GAL1 APOH MTHFD1 PLCB1 ARC MAPK8 TAPBP CNR1

1.36e-0488311212C0036341
DiseaseNephrotic Syndrome

A2M HLA-DRB1 ALB

1.46e-04271123C0027726
DiseaseC-reactive protein measurement

SLAMF8 TDRD15 CACNB2 HLA-DRB1 APOH PPL SLC38A1 CSNK1G2 NTM OASL AACS BSN GCN1 TOP2B

1.93e-04120611214EFO_0004458
DiseaseIdiopathic Membranous Glomerulonephritis

HLA-DRB1 ALB

2.12e-0461122C0086445
DiseaseHeymann Nephritis

HLA-DRB1 ALB

2.12e-0461122C1704378
DiseaseAngioedema

HLA-DRB1 ALB

2.12e-0461122C0002994
DiseaseMembranous glomerulonephritis

HLA-DRB1 ALB

2.12e-0461122C0017665
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

TDRD15 HLA-DRB1 APOH SLC38A1 LRBA

2.75e-041501125EFO_0004611, EFO_0020947
Diseaseantiphospholipid syndrome (is_implicated_in)

HLA-DRB1 APOH

3.94e-0481122DOID:2988 (is_implicated_in)
Diseasecholesteryl ester measurement

TDRD15 HLA-DRB1 APOH CYP39A1 SLC38A1 OASL

4.56e-042571126EFO_0010351
Diseasehematocrit

TDRD15 PDE9A HLA-DRB1 FBRSL1 SORBS1 FAT1 SPPL2A CLCNKB ZC3H4 OASL PLCB1 BSN

4.67e-04101111212EFO_0004348
Diseaseintermittent Staphylococcus aureus carrier status

KAT2B ROBO1

5.05e-0491122EFO_0007758
DiseaseAntihypertensive use measurement

CACNB2 CYP27B1 KAT2B NTM PLCB1 LRBA

5.36e-042651126EFO_0009927
Diseaseheart disease (is_marker_for)

A2M ALB

6.30e-04101122DOID:114 (is_marker_for)
DiseaseWNT1-inducible-signaling pathway protein 1 measurement

SLC46A1 C8B

6.30e-04101122EFO_0008321
DiseaseParanoia

ICE2 HLA-DRB4

7.68e-04111122C1456784
Diseaseaspirin-induced respiratory disease (is_implicated_in)

HLA-DRB1 HLA-DRB4

7.68e-04111122DOID:0080822 (is_implicated_in)
DiseasePain, Migratory

PLCB1 ALB CNR1

8.64e-04491123C0751407
DiseaseSuffering, Physical

PLCB1 ALB CNR1

8.64e-04491123C0751408
DiseasePain, Crushing

PLCB1 ALB CNR1

8.64e-04491123C0458259
DiseasePain, Splitting

PLCB1 ALB CNR1

8.64e-04491123C0458257
DiseasePain

PLCB1 ALB CNR1

8.64e-04491123C0030193
DiseaseRadiating pain

PLCB1 ALB CNR1

8.64e-04491123C0234254
DiseasePain, Burning

PLCB1 ALB CNR1

8.64e-04491123C0234230
DiseaseAche

PLCB1 ALB CNR1

8.64e-04491123C0234238
Diseasecholesteryl esters to total lipids in small VLDL percentage

TDRD15 HLA-DRB1 APOH

8.64e-04491123EFO_0022256
Diseasecognitive inhibition measurement

CACNB2 HLA-DRB1 TGM5

9.16e-04501123EFO_0007969
Diseaseacute myeloid leukemia (implicated_via_orthology)

SF3B1 TOP2B

9.19e-04121122DOID:9119 (implicated_via_orthology)
Diseaseabdominal aortic aneurysm (is_implicated_in)

HLA-DRB1 MAPK8

9.19e-04121122DOID:7693 (is_implicated_in)
Diseasehepatocellular carcinoma (is_marker_for)

SLC38A1 KAT2B SF3B1 ABCE1 ALB MAPK8

1.04e-033011126DOID:684 (is_marker_for)
Diseaseage at menopause

FRYL TUBGCP4 AK8 RIF1 EIF4E TAPBP

1.06e-033021126EFO_0004704
Diseasecholesterol to total lipids in very large VLDL percentage

TDRD15 HLA-DRB1 APOH

1.15e-03541123EFO_0022244
Diseasemembranous glomerulonephritis (biomarker_via_orthology)

A2M MAP3K5

1.26e-03141122DOID:10976 (biomarker_via_orthology)
DiseaseC-C motif chemokine 19 measurement

HLA-DRB1 BSN

1.26e-03141122EFO_0008047
DiseaseGDH/6PGL endoplasmic bifunctional protein measurement

HLA-DRB1 APOH

1.26e-03141122EFO_0801619
Diseasetriglycerides in LDL measurement

TDRD15 HLA-DRB1 SLC38A1

1.27e-03561123EFO_0022320
Diseasetriglycerides in chylomicrons and extremely large VLDL measurement

HLA-DRB1 APOH SLC38A1

1.27e-03561123EFO_0022316
DiseaseCalcium channel blocker use measurement

CACNB2 CYP27B1 SLC38A1 FAT1 PLCB1

1.34e-032131125EFO_0009930
Diseasetriglycerides in IDL measurement

TDRD15 HLA-DRB1 SLC38A1

1.41e-03581123EFO_0022149
Diseaseinterleukin 18 receptor 1 measurement

APOH IL1RL2

1.45e-03151122EFO_0008178
DiseasePancreatitis

HLA-DRB1 ALB CNR1

1.48e-03591123C0030305
Diseaseconcentration of chylomicrons and extremely large VLDL particles measurement

HLA-DRB1 APOH SLC38A1

1.48e-03591123EFO_0022260
Diseasefree cholesterol to total lipids in very large VLDL percentage

TDRD15 HLA-DRB1 APOH

1.48e-03591123EFO_0022289
Diseasecholesterol in chylomicrons and extremely large VLDL measurement

HLA-DRB1 APOH SLC38A1

1.56e-03601123EFO_0021898
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

TDRD15 HLA-DRB1 APOH SLC38A1 LRBA

1.61e-032221125EFO_0008317, EFO_0020943
DiseaseUrticaria

HLA-DRB1 ALB

1.65e-03161122C0042109
Diseasetriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement

TDRD15 HLA-DRB1 APOH SLC38A1 LRBA

1.71e-032251125EFO_0008317, EFO_0020947
Diseasetriglycerides in medium LDL measurement

TDRD15 HLA-DRB1 SLC38A1

1.71e-03621123EFO_0022322
Diseasetotal lipids in chylomicrons and extremely large VLDL measurement

HLA-DRB1 APOH SLC38A1

1.71e-03621123EFO_0022306
Diseasefree cholesterol in chylomicrons and extremely large VLDL measurement

HLA-DRB1 APOH SLC38A1

1.71e-03621123EFO_0022263
Diseasecholesterol to total lipids in medium VLDL percentage

TDRD15 HLA-DRB1 APOH

1.79e-03631123EFO_0022239
Diseasephospholipids in chylomicrons and extremely large VLDL measurement

HLA-DRB1 APOH SLC38A1

1.79e-03631123EFO_0022292
DiseaseAllergic Reaction

HLA-DRB1 HLA-DRB4 ALB

1.79e-03631123C1527304
DiseaseAntibody Deficiency Syndrome

C5 C8B

1.87e-03171122C0003257
Diseasecholesterol to total lipids in chylomicrons and extremely large VLDL percentage

TDRD15 APOH

1.87e-03171122EFO_0022232
DiseaseHypersensitivity

HLA-DRB1 HLA-DRB4 ALB

1.87e-03641123C0020517
Diseasecholesteryl esters to total lipids in medium VLDL percentage

TDRD15 HLA-DRB1 APOH

1.87e-03641123EFO_0022253
Diseasecoronary artery disease

TDRD15 KHDRBS2 APOH NEK9 PDXK SLC38A1 CSNK1G2 CARF C5 DENND5A BSN ARHGAP20

1.95e-03119411212EFO_0001645
Diseasetriglycerides in small LDL measurement

TDRD15 HLA-DRB1 SLC38A1

1.96e-03651123EFO_0022323
DiseaseMyeloid Leukemia

ATG2B TOP2B

2.10e-03181122C0023470
DiseaseLeukemia, Monocytic, Chronic

ATG2B TOP2B

2.10e-03181122C0023466
Diseasetotal lipids in large VLDL

TDRD15 HLA-DRB1 APOH

2.14e-03671123EFO_0022175
Diseasetriglycerides in very small VLDL measurement

TDRD15 HLA-DRB1 SLC38A1

2.23e-03681123EFO_0022144
Diseaseaspartate aminotransferase measurement

CACNB2 HLA-DRB1 KHDRBS2 OBSCN ST3GAL1 APOH ROBO1 LRBA GCN1 MOV10

2.35e-0390411210EFO_0004736
Diseaseserum gamma-glutamyl transferase measurement

ICE2 SLC38A1 KAT2B SPPL2A CLCNKB OASL ROBO1 LRBA GCN1 CDH6

2.55e-0391411210EFO_0004532
Diseaselow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

TDRD15 HLA-DRB1 APOH SLC38A1

2.80e-031531124EFO_0004611, EFO_0020946
Diseaselow density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

TDRD15 HLA-DRB1 APOH SLC38A1

2.80e-031531124EFO_0004611, EFO_0020944
DiseaseLymphoma, Diffuse

HLA-DRB1 CASP10

2.86e-03211122C3714542
DiseaseLow Grade Lymphoma (neoplasm)

HLA-DRB1 CASP10

2.86e-03211122C0079747
DiseaseLymphoma, Intermediate-Grade

HLA-DRB1 CASP10

2.86e-03211122C0079741
DiseaseHigh Grade Lymphoma (neoplasm)

HLA-DRB1 CASP10

2.86e-03211122C0079740
DiseaseDiffuse Mixed-Cell Lymphoma

HLA-DRB1 CASP10

2.86e-03211122C0079757
DiseaseLymphoma, Undifferentiated

HLA-DRB1 CASP10

2.86e-03211122C0024306
DiseaseReticulosarcoma

HLA-DRB1 CASP10

2.86e-03211122C0024302
DiseaseLymphoma, Mixed-Cell

HLA-DRB1 CASP10

2.86e-03211122C0024304
Diseasefree cholesterol to total lipids in small VLDL percentage

HLA-DRB1 APOH SLC38A1

2.95e-03751123EFO_0022287
DiseaseLymphoma, Non-Hodgkin, Familial

HLA-DRB1 CASP10

3.14e-03221122C4721532
DiseaseLymphoma, Small Noncleaved-Cell

HLA-DRB1 CASP10

3.14e-03221122C0079770
Diseasemyocardial infarction (biomarker_via_orthology)

MAP1LC3A PLCB1 C8B MAPK8

3.28e-031601124DOID:5844 (biomarker_via_orthology)
DiseaseImmunologic Deficiency Syndromes

C5 C8B

3.43e-03231122C0021051
Diseasevitronectin measurement

SLC46A1 C8B

3.43e-03231122EFO_0021843
DiseaseEtat Marbre

ARC CNR1

3.43e-03231122C0266487
DiseaseLiver Failure, Acute

ALB MAPK8

3.73e-03241122C0162557

Protein segments in the cluster

PeptideGeneStartEntry
KPVSRIVKPQPVYEI

BHLHB9

191

Q6PI77
IVKPQPVYEINEKNR

BHLHB9

196

Q6PI77
QPKVSDPYRAVVKVS

FBRSL1

526

Q9HCM7
LLVRYTKKVPQVSTP

ALB

431

P02768
VPVKKATVVYQGERV

APOH

266

P02749
PIVVIARVVPNYKEF

CCDC33

401

Q8N5R6
PDLKKVVVIPYVSSR

AACS

231

Q86V21
VKAPLQERYVEKIII

ACR

116

P10323
PVLERYTSVVTLVKP

COQ10B

131

Q9H8M1
IIQYVVGTLQPKLKR

ARC

321

Q7LC44
PVTTVLIKRPDLKYQ

APBA2

656

Q99767
TPALEKVVPLKRIYI

DAPL1

86

A0PJW8
FPIPVIRYVVKEVSL

ATG2B

1541

Q96BY7
DVPVRDLKPAIVKVY

A2M

1436

P01023
PIIVYVKISSPKVLQ

CACNB2

391

Q08289
IRVKRYEKVPVILVG

RAP2A

101

P10114
VLEKYKVHNPTPLIV

ITGAX

1096

P20702
QHPTKIPVIIERYKG

MAP1LC3B

26

Q9GZQ8
IPVIIERYKGEKQLP

MAP1LC3B

31

Q9GZQ8
KAVVKEVLRLYPVVP

CYP27B1

371

O15528
PSKESVVLVYVKILP

FAT1

2681

Q14517
IVQLYVAPAPEKSRK

SLC46A1

251

Q96NT5
VALEVPPKREVVVYA

HELLS

456

Q9NRZ9
IYIKIPQVPLCVSYK

KIAA0100

2116

Q14667
VQVLKEKPYPIAEVE

LONP2

111

Q86WA8
YTPQKVDVPKALIIV

NEK9

521

Q8TD19
KPEPVYKLTQRQVNI

HACD3

66

Q9P035
NPRIPYTEFSVIIKK

KAT2B

651

Q92831
VVRRVKVTVNYPPYI

NTM

211

Q9P121
RELYVPRIASKPIIV

MTMR6

161

Q9Y217
KVKQKVPAPRYTVEL

IL1RAP

346

Q9NPH3
RVYKERLGLPPKIVI

EIF4E

181

P06730
YVAIKLEPIKSRAPQ

CSNK1G2

71

P78368
PKVEIVRYISAPEKT

BSN

2696

Q9UPA5
IKKVQKFPEYRVPTD

CARF

321

Q8N187
YKVPTPIQRKTIPVI

DDX54

116

Q8TDD1
VTVPNLKPLTVYCVK

IFNAR1

391

P17181
IVRVIPSYPKILKVI

AK8

226

Q96MA6
PLPGYKVREIVEKIL

PLS1

46

Q14651
IDIKKYQVLVGEPVR

IL1RAPL1

36

Q9NZN1
KLQPTVRTYVENRPK

MAPK8

251

P45983
QQVVPLKYRRETPLK

PPL

386

O60437
SERTPYKVRPVAIKQ

PDE9A

71

O76083
EPSLLPYVKKVIVYL

FRYL

1416

O94915
PEKVIVKTRTEYQPE

NSG2

41

Q9Y328
ATVKKVVNYLPRVGV

LRBA

2171

P50851
IRKKYPDRVPVIVEK

GABARAP

21

O95166
VEILPSYIPVRVAEK

TUBGCP4

261

Q9UGJ1
IKSRVVLPYLVPKLT

GCN1

2071

Q92616
PLTNPIVYCVKTKQI

OR51A4

286

Q8NGJ6
KRYVLPKFEVTVNAP

OVOS2

201

Q6IE36
PLKPRISITKGVIYI

GPR83

176

Q9NYM4
APSVVPLKKIYDVEQ

IQGAP3

76

Q86VI3
TTERKYNLKVHVPPV

HMCN1

1346

Q96RW7
FNLIVNPYEPIRKVK

OASL

366

Q15646
KILVQVPPRFVNKVR

OBSCN

6101

Q5VST9
VPYVNSPGEKLRIKQ

PRICKLE2

61

Q7Z3G6
PQGKYKVLPTERTKV

PHF10

236

Q8WUB8
VPKIIYPKNHSIEVQ

IL1RL2

226

Q9HB29
YLIAFQVPRPKIKLI

RGPD3

321

A6NKT7
AIIKPQYVDQIPKAA

ABCE1

166

P61221
KVKPFVVRDAVVYPI

HYOU1

431

Q9Y4L1
KKIRRQFPVYVLPKV

ICE2

761

Q659A1
PGYAKVIKKVIIPAR

CPZ

556

Q66K79
IRKKYPDRVPVIVEK

GABARAPL1

21

Q9H0R8
TIRLEIISNKPYKIP

DIS3L

966

Q8TF46
PETPYLRKHKVIFVV

COL6A5

2071

A8TX70
DKPVYTPDQSVKVRV

C5

131

P01031
FRIRPVTPVEKYIKV

C20orf85

71

Q9H1P6
IPYRSVIIPIKKLSN

DENND5B

936

Q6ZUT9
QRRVQPKVTVYPSKT

HLA-DRB1

121

P01911
PLAYKRIVTRPKAVV

CNR1

221

P21554
TILIPYHILIVPSKK

DENND5A

951

Q6IQ26
QRRVQPKVTVYPSKT

HLA-DRB4

121

P13762
RPEPQLKGIVTKLYS

FGF13

61

Q92913
SERVLIPVKQYPKFN

KHDRBS2

61

Q5VWX1
EKYKREKAIQIVTPP

CASP10

186

Q92851
PKQSSRVPLYIKVLD

CDH6

466

P55285
RKVVKPVEILNYIIP

CYP39A1

346

Q9NYL5
VPVIQPYRLDSKVKQ

POLRMT

1076

O00411
PVEDKIRIIAQKIYG

MTHFD1

821

P11586
VQYNPAIIKVKVEPL

C8B

456

P07358
PIIYGVKTKQIRESI

OR52K2

291

Q8NGK3
VVRFPVLILEPTKIY

MAP3K5

556

Q99683
ESKPVNILVYTKIPL

ARHGAP20

656

Q9P2F6
YLIAFQVPRPKIKLI

RGPD4

321

Q7Z3J3
IVPYPRKITLIKQLA

RIMBP2

296

O15034
SVAIPKASRVKPVEY

TRNAU1AP

171

Q9NX07
NKKVIDPVAPRYVAL

EPRS1

496

P07814
RYVALLKKEVIPVNV

EPRS1

506

P07814
IPVVEHKVEKVYVPA

TOP2B

146

Q02880
VVPKFKLSYIQPRTQ

TC2N

76

Q8N9U0
VINKPSPVTYSERKI

TDRD15

1181

B5MCY1
SVGVISPYRKQVEKI

MOV10

826

Q9HCE1
VYPEELKPVLTQAKQ

RIF1

946

Q5UIP0
VTRKEPPVIIKYIII

NEXMIF

531

Q5QGS0
PPVIIKYIIINRFKG

NEXMIF

536

Q5QGS0
RPAELYTQIIAVKPT

SMARCAL1

586

Q9NZC9
ISHTYIPVPAKIRVK

ST3GAL1

226

Q11201
IPIKYPLKEIVVIHQ

IARS1

841

P41252
IPVIIERYKGEKQLP

MAP1LC3A

31

Q9H492
LITIYKKPISAIPAR

RASGRF1

691

Q13972
YKEKVVPLADIITPN

PDXK

136

O00764
LKVKIPEPHTQARVY

AHNAK2

5521

Q8IVF2
DGTVIVKKLPYLPRI

CLCNKB

521

P51801
LEREKPQTKILYITP

RECQL5

116

O94762
QHPTKIPVIIERYKG

MAP1LC3B2

26

A6NCE7
IPVIIERYKGEKQLP

MAP1LC3B2

31

A6NCE7
TVVNALGKRVKPYLP

SF3B1

916

O75533
QVTLELAVYKPPKVS

TAPBP

281

O15533
KIPKDYVVQVIVSQP

UBTD2

211

Q8WUN7
EKLPVVIRVPKLIYF

SPPL2A

381

Q8TCT8
TYVDVIKRPLVKNPV

SORBS1

921

Q9BX66
RVPVEKPVYKNLQLF

TOP1MT

376

Q969P6
IRVPFLRQVVPISKK

RRP36

101

Q96EU6
VVIPDLRKGVNYEIK

ROBO1

736

Q9Y6N7
TLQLKVYDAVPRPVV

SLAMF8

116

Q9P0V8
PEKILVNKIITLSYP

TGM5

606

O43548
YTKLKLQVTPEGRIP

PLCB1

156

Q9NQ66
SYKVQPVAIVRPLER

SAXO2

56

Q658L1
YNKKIPSLFEIVVRP

ZC3H4

576

Q9UPT8
FIREVTPYIKKPSLV

SNTB2

196

Q13425
RKVIELPNIQKVEVY

USP11

181

P51784
VIYKKFQIPCIVPEL

SLC38A1

236

Q9H2H9