Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	FRAS1 ANOS1 POMZP3 ACAN LAMA1 SSPOP	1.41e-05	188	56	6	GO:0005201
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	KMT2B KMT2A	2.14e-04	8	56	2	GO:0140945
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	KMT2B NSD2 KMT2A	2.55e-04	44	56	3	GO:0140938
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	KMT2B KMT2A	3.43e-04	10	56	2	GO:0140999
GeneOntologyMolecularFunction	unmethylated CpG binding	KMT2B KMT2A	3.43e-04	10	56	2	GO:0045322
GeneOntologyMolecularFunction	structural constituent of postsynaptic actin cytoskeleton	POTEI POTEJ	4.18e-04	11	56	2	GO:0098973
GeneOntologyMolecularFunction	structural molecule activity	FRAS1 ANOS1 POMZP3 ACAN INSR LAMA1 POTEI POTEJ SSPOP	7.73e-04	891	56	9	GO:0005198
GeneOntologyMolecularFunction	protein-lysine N-methyltransferase activity	KMT2B NSD2 KMT2A	9.20e-04	68	56	3	GO:0016279
GeneOntologyMolecularFunction	lysine N-methyltransferase activity	KMT2B NSD2 KMT2A	9.60e-04	69	56	3	GO:0016278
GeneOntologyMolecularFunction	histone methyltransferase activity	KMT2B NSD2 KMT2A	1.04e-03	71	56	3	GO:0042054
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	KMT2B KMT2A	1.42e-03	20	56	2	GO:0042800
GeneOntologyMolecularFunction	peptidase inhibitor activity	WFDC3 ANOS1 WFDC8 SSPOP	1.87e-03	187	56	4	GO:0030414
GeneOntologyMolecularFunction	protein methyltransferase activity	KMT2B NSD2 KMT2A	3.03e-03	103	56	3	GO:0008276
GeneOntologyMolecularFunction	N-methyltransferase activity	KMT2B NSD2 KMT2A	3.20e-03	105	56	3	GO:0008170
GeneOntologyMolecularFunction	serine-type endopeptidase inhibitor activity	WFDC3 ANOS1 WFDC8	3.20e-03	105	56	3	GO:0004867
GeneOntologyMolecularFunction	structural constituent of postsynapse	POTEI POTEJ	3.63e-03	32	56	2	GO:0099186
GeneOntologyMolecularFunction	ubiquitin protein ligase activity	TRAF3 NFX1 CBLC G2E3 UHRF2	3.83e-03	372	56	5	GO:0061630
GeneOntologyCellularComponent	extracellular matrix	FRAS1 ANOS1 POMZP3 FCGBP OTOGL ACAN WNT3 LAMA1 SSPOP	5.66e-05	656	56	9	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	FRAS1 ANOS1 POMZP3 FCGBP OTOGL ACAN WNT3 LAMA1 SSPOP	5.80e-05	658	56	9	GO:0030312
GeneOntologyCellularComponent	protein complex involved in cell adhesion	ITGBL1 LAMA1 ITGB8	5.32e-04	59	56	3	GO:0098636
GeneOntologyCellularComponent	Wnt signalosome	WNT3 LRP5	8.26e-04	16	56	2	GO:1990909
GeneOntologyCellularComponent	plasma membrane protein complex	ITGBL1 ERBB2 TRAF3 INSR SCN10A LRP5 SSPOP ITGB8	1.10e-03	785	56	8	GO:0098797
GeneOntologyCellularComponent	keratin filament	KRTAP10-4 KRTAP10-7 KRTAP10-6	2.25e-03	97	56	3	GO:0045095
GeneOntologyCellularComponent	plasma membrane signaling receptor complex	ITGBL1 ERBB2 TRAF3 INSR ITGB8	2.43e-03	350	56	5	GO:0098802
GeneOntologyCellularComponent	Golgi lumen	ACAN WNT3 PROC	3.13e-03	109	56	3	GO:0005796
GeneOntologyCellularComponent	H4/H2A histone acetyltransferase complex	POTEI POTEJ	3.32e-03	32	56	2	GO:0043189
GeneOntologyCellularComponent	NuA4 histone acetyltransferase complex	POTEI POTEJ	3.32e-03	32	56	2	GO:0035267
GeneOntologyCellularComponent	integrin complex	ITGBL1 ITGB8	3.32e-03	32	56	2	GO:0008305
GeneOntologyCellularComponent	MLL1/2 complex	KMT2B KMT2A	3.53e-03	33	56	2	GO:0044665
GeneOntologyCellularComponent	transferase complex	TRAF3 KMT2B INSR CBLC KMT2A ZNFX1 POTEI POTEJ	3.93e-03	963	56	8	GO:1990234
GeneOntologyCellularComponent	basement membrane	FRAS1 ACAN LAMA1	4.29e-03	122	56	3	GO:0005604
GeneOntologyCellularComponent	receptor complex	ITGBL1 ERBB2 TRAF3 INSR LRP5 ITGB8	4.49e-03	581	56	6	GO:0043235
Domain	EGF-like_dom	ITGBL1 FRAS1 FCGBP ADAM18 SLIT3 LAMA1 LRP5 VWCE NAGPA ADAM12 VWDE PROC	3.98e-12	249	53	12	IPR000742
Domain	EGF_1	ITGBL1 ADAM18 SLIT3 LAMA1 LRP5 VWCE NAGPA ADAM12 SSPOP VWDE ITGB8 PROC	5.26e-12	255	53	12	PS00022
Domain	EGF_2	ITGBL1 ADAM18 SLIT3 LAMA1 LRP5 VWCE NAGPA ADAM12 SSPOP VWDE ITGB8 PROC	8.26e-12	265	53	12	PS01186
Domain	EGF	ITGBL1 FRAS1 FCGBP SLIT3 LAMA1 LRP5 VWCE NAGPA VWDE ITGB8 PROC	4.74e-11	235	53	11	SM00181
Domain	EGF-like_CS	ADAM18 SLIT3 LAMA1 LRP5 VWCE NAGPA ADAM12 VWDE ITGB8 PROC	2.75e-09	261	53	10	IPR013032
Domain	PHD	KMT2B NSD2 PHF12 PHF6 KMT2A G2E3 UHRF2	5.66e-09	89	53	7	SM00249
Domain	Znf_PHD	KMT2B NSD2 PHF12 PHF6 KMT2A G2E3 UHRF2	6.62e-09	91	53	7	IPR001965
Domain	ZF_PHD_2	KMT2B NSD2 PHF12 PHF6 KMT2A G2E3 UHRF2	8.96e-09	95	53	7	PS50016
Domain	ZF_PHD_1	KMT2B NSD2 PHF12 PHF6 KMT2A G2E3 UHRF2	9.65e-09	96	53	7	PS01359
Domain	EGF_3	ADAM18 SLIT3 LRP5 VWCE NAGPA ADAM12 SSPOP VWDE PROC	1.86e-08	235	53	9	PS50026
Domain	ZnF_NFX	NFX1 NFXL1 ZNFX1	2.16e-08	3	53	3	SM00438
Domain	zf-NF-X1	NFX1 NFXL1 ZNFX1	2.16e-08	3	53	3	PF01422
Domain	Znf_NFX1	NFX1 NFXL1 ZNFX1	2.16e-08	3	53	3	IPR000967
Domain	Znf_RING/FYVE/PHD	TRAF3 KMT2B CGRRF1 NSD2 PHF12 PHF6 CBLC KMT2A G2E3 UHRF2 WDR59	5.27e-08	459	53	11	IPR013083
Domain	VWC	FRAS1 FCGBP CHRD VWCE SSPOP	7.09e-08	38	53	5	SM00214
Domain	Znf_PHD-finger	KMT2B NSD2 PHF12 NFX1 KMT2A UHRF2	9.25e-08	79	53	6	IPR019787
Domain	VWF_dom	FRAS1 FCGBP CHRD VWCE SSPOP	1.19e-07	42	53	5	IPR001007
Domain	VWC_out	FRAS1 FCGBP VWCE SSPOP	2.17e-07	19	53	4	SM00215
Domain	EPHD	KMT2B PHF6 KMT2A G2E3	4.07e-07	22	53	4	PS51805
Domain	-	TRAF3 KMT2B CGRRF1 NSD2 PHF12 PHF6 CBLC KMT2A G2E3 UHRF2	4.51e-07	449	53	10	3.30.40.10
Domain	EGF_extracell	ITGBL1 ADAM18 NAGPA ADAM12 ITGB8	7.36e-07	60	53	5	IPR013111
Domain	EGF_2	ITGBL1 ADAM18 NAGPA ADAM12 ITGB8	7.36e-07	60	53	5	PF07974
Domain	Zinc_finger_PHD-type_CS	NSD2 PHF12 NFX1 NFXL1 G2E3	1.10e-06	65	53	5	IPR019786
Domain	PHD	KMT2B NSD2 PHF12 KMT2A UHRF2	2.25e-06	75	53	5	PF00628
Domain	VWFC_1	FRAS1 CHRD VWCE SSPOP	3.18e-06	36	53	4	PS01208
Domain	Znf_RING	TRAF3 CGRRF1 NSD2 NFX1 NFXL1 CBLC G2E3 UHRF2	3.54e-06	326	53	8	IPR001841
Domain	Znf_FYVE_PHD	KMT2B NSD2 PHF12 KMT2A G2E3 UHRF2	3.63e-06	147	53	6	IPR011011
Domain	VWFC_2	FRAS1 CHRD VWCE SSPOP	3.97e-06	38	53	4	PS50184
Domain	Growth_fac_rcpt_	ERBB2 FRAS1 SLIT3 INSR LAMA1 VWCE	5.12e-06	156	53	6	IPR009030
Domain	MeTrfase_trithorax	KMT2B KMT2A	7.90e-06	2	53	2	IPR016569
Domain	Post-SET_dom	KMT2B NSD2 KMT2A	1.18e-05	16	53	3	IPR003616
Domain	VWD	FCGBP SSPOP VWDE	1.18e-05	16	53	3	SM00216
Domain	WAP	WFDC3 ANOS1 WFDC8	1.18e-05	16	53	3	SM00217
Domain	PostSET	KMT2B NSD2 KMT2A	1.18e-05	16	53	3	SM00508
Domain	VWF_type-D	FCGBP SSPOP VWDE	1.18e-05	16	53	3	IPR001846
Domain	VWFD	FCGBP SSPOP VWDE	1.18e-05	16	53	3	PS51233
Domain	POST_SET	KMT2B NSD2 KMT2A	1.18e-05	16	53	3	PS50868
Domain	WAP	WFDC3 ANOS1 WFDC8	1.18e-05	16	53	3	PF00095
Domain	VWD	FCGBP SSPOP VWDE	1.18e-05	16	53	3	PF00094
Domain	WAP	WFDC3 ANOS1 WFDC8	1.43e-05	17	53	3	PS51390
Domain	-	WFDC3 ANOS1 WFDC8	1.43e-05	17	53	3	4.10.75.10
Domain	Furin_repeat	ERBB2 FRAS1 INSR	1.71e-05	18	53	3	IPR006212
Domain	FU	ERBB2 FRAS1 INSR	1.71e-05	18	53	3	SM00261
Domain	RING	TRAF3 CGRRF1 NSD2 NFX1 CBLC G2E3 UHRF2	2.34e-05	305	53	7	SM00184
Domain	WAP_dom	WFDC3 ANOS1 WFDC8	3.20e-05	22	53	3	IPR008197
Domain	VWC	FRAS1 CHRD VWCE	6.72e-05	28	53	3	PF00093
Domain	FYrich_C	KMT2B KMT2A	7.86e-05	5	53	2	IPR003889
Domain	FYrich_N	KMT2B KMT2A	7.86e-05	5	53	2	IPR003888
Domain	FYRC	KMT2B KMT2A	7.86e-05	5	53	2	SM00542
Domain	FYRN	KMT2B KMT2A	7.86e-05	5	53	2	SM00541
Domain	FYRN	KMT2B KMT2A	7.86e-05	5	53	2	PF05964
Domain	FYRC	KMT2B KMT2A	7.86e-05	5	53	2	PF05965
Domain	FYRC	KMT2B KMT2A	7.86e-05	5	53	2	PS51543
Domain	FYRN	KMT2B KMT2A	7.86e-05	5	53	2	PS51542
Domain	Furin-like	ERBB2 INSR	1.64e-04	7	53	2	PF00757
Domain	Rcpt_L-dom	ERBB2 INSR	1.64e-04	7	53	2	IPR000494
Domain	Furin-like_Cys-rich_dom	ERBB2 INSR	1.64e-04	7	53	2	IPR006211
Domain	Recep_L_domain	ERBB2 INSR	1.64e-04	7	53	2	PF01030
Domain	-	ERBB2 INSR	1.64e-04	7	53	2	3.80.20.20
Domain	ZF_RING_1	TRAF3 CGRRF1 NFX1 NFXL1 CBLC UHRF2	1.69e-04	291	53	6	PS00518
Domain	EGF_CA	SLIT3 LRP5 VWCE PROC	1.78e-04	99	53	4	PS01187
Domain	ZF_RING_2	TRAF3 CGRRF1 NFX1 NFXL1 CBLC UHRF2	1.92e-04	298	53	6	PS50089
Domain	SET	KMT2B NSD2 KMT2A	2.13e-04	41	53	3	PF00856
Domain	Integrin_bsu	ITGBL1 ITGB8	2.81e-04	9	53	2	IPR015812
Domain	INTEGRIN_BETA	ITGBL1 ITGB8	2.81e-04	9	53	2	PS00243
Domain	SET	KMT2B NSD2 KMT2A	3.00e-04	46	53	3	SM00317
Domain	SET_dom	KMT2B NSD2 KMT2A	3.85e-04	50	53	3	IPR001214
Domain	SET	KMT2B NSD2 KMT2A	3.85e-04	50	53	3	PS50280
Domain	EGF-like_Ca-bd_dom	SLIT3 LRP5 VWCE PROC	4.21e-04	124	53	4	IPR001881
Domain	Fol_N	FCGBP FSTL3	4.27e-04	11	53	2	IPR003645
Domain	Znf_CXXC	KMT2B KMT2A	4.27e-04	11	53	2	IPR002857
Domain	ZF_CXXC	KMT2B KMT2A	4.27e-04	11	53	2	PS51058
Domain	zf-CXXC	KMT2B KMT2A	4.27e-04	11	53	2	PF02008
Domain	FOLN	FCGBP FSTL3	4.27e-04	11	53	2	SM00274
Domain	EGF	SLIT3 LRP5 NAGPA PROC	4.48e-04	126	53	4	PF00008
Domain	TIL	FCGBP SSPOP	5.12e-04	12	53	2	PF01826
Domain	C8	FCGBP SSPOP	5.12e-04	12	53	2	PF08742
Domain	KAP	KRTAP10-4 KRTAP10-7 KRTAP10-6	5.96e-04	58	53	3	IPR002494
Domain	Unchr_dom_Cys-rich	FCGBP SSPOP	6.04e-04	13	53	2	IPR014853
Domain	C8	FCGBP SSPOP	6.04e-04	13	53	2	SM00832
Domain	TIL_dom	FCGBP SSPOP	7.03e-04	14	53	2	IPR002919
Domain	Disintegrin_CS	ADAM18 ADAM12	9.24e-04	16	53	2	IPR018358
Domain	Actin_CS	POTEI POTEJ	9.24e-04	16	53	2	IPR004001
Domain	ACTINS_2	POTEI POTEJ	1.05e-03	17	53	2	PS00432
Domain	CTCK_1	SLIT3 SSPOP	1.17e-03	18	53	2	PS01185
Domain	ADAM_CR	ADAM18 ADAM12	1.17e-03	18	53	2	PF08516
Domain	Actin/actin-like_CS	POTEI POTEJ	1.17e-03	18	53	2	IPR020902
Domain	ACTINS_ACT_LIKE	POTEI POTEJ	1.31e-03	19	53	2	PS01132
Domain	-	ADAM18 ADAM12	1.45e-03	20	53	2	4.10.70.10
Domain	Disintegrin	ADAM18 ADAM12	1.60e-03	21	53	2	PF00200
Domain	DISIN	ADAM18 ADAM12	1.60e-03	21	53	2	SM00050
Domain	Cys_knot_C	SLIT3 SSPOP	2.27e-03	25	53	2	IPR006207
Domain	CTCK_2	SLIT3 SSPOP	2.27e-03	25	53	2	PS01225
Domain	EGF_Ca-bd_CS	SLIT3 VWCE PROC	2.64e-03	97	53	3	IPR018097
Domain	ACR	ADAM18 ADAM12	2.65e-03	27	53	2	SM00608
Domain	ADAM_Cys-rich	ADAM18 ADAM12	2.65e-03	27	53	2	IPR006586
Domain	AT_hook	KMT2B KMT2A	2.65e-03	27	53	2	SM00384
Domain	AT_hook_DNA-bd_motif	KMT2B KMT2A	2.65e-03	27	53	2	IPR017956
Pubmed	POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer.	POTEJ POTEB2 POTEB	2.45e-07	8	58	3	12475935
Pubmed	Hair keratin associated proteins: characterization of a second high sulfur KAP gene domain on human chromosome 21.	KRTAP10-4 KRTAP10-7 KRTAP10-6	7.19e-07	11	58	3	14962103
Pubmed	A cluster of 21 keratin-associated protein genes within introns of another gene on human chromosome 21q22.3.	KRTAP10-4 KRTAP10-7 KRTAP10-6	2.43e-06	16	58	3	15028290
Pubmed	A positive feedback loop between HER2 and ADAM12 in human head and neck cancer cells increases migration and invasion.	ERBB2 ADAM12	2.73e-06	2	58	2	21986939
Pubmed	KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions.	KMT2B KMT2A	2.73e-06	2	58	2	28723559
Pubmed	Lack of Lrp5 Signaling in Osteoblasts Sensitizes Male Mice to Diet-Induced Disturbances in Glucose Metabolism.	INSR LRP5	2.73e-06	2	58	2	28938444
Pubmed	Erbb2 up-regulation of ADAM12 expression accelerates skin cancer progression.	ERBB2 ADAM12	2.73e-06	2	58	2	24798404
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	ITGBL1 FSTL3 ACAN SLIT3 LAMA1 ADAM12	3.67e-06	248	58	6	24006456
Pubmed	The Vertebrate Genome Annotation browser 10 years on.	ZNFX1 POTEI POTEJ POTEB2 POTEB	7.97e-06	163	58	5	24316575
Pubmed	Prognostic Impact of FSTL3, ADAM12, and FAT4 in Patients of Colon Cancer: Clinicopathologic Study.	FSTL3 ADAM12	8.19e-06	3	58	2	37751246
Pubmed	Expression of Wnt3 activates Wnt/β-catenin pathway and promotes EMT-like phenotype in trastuzumab-resistant HER2-overexpressing breast cancer cells.	ERBB2 WNT3	8.19e-06	3	58	2	23071104
Pubmed	LncRNA ubiquitin-binding protein domain protein 10 antisense RNA 1 inhibits colon adenocarcinoma progression via the miR-515-5p/slit guidance ligand 3 axis.	SLIT3 PLA2G2C	8.19e-06	3	58	2	35034539
Pubmed	Interaction between LRP5 and Frat1 mediates the activation of the Wnt canonical pathway.	WNT3 LRP5	8.19e-06	3	58	2	15699046
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ERBB2 FRAS1 INTS5 KMT2B NSD2 PHF12 NFX1 CBLC LRP5 WDR59	1.31e-05	1105	58	10	35748872
Pubmed	Nav1.7 as a chondrocyte regulator and therapeutic target for osteoarthritis.	ACAN SCN10A	1.64e-05	4	58	2	38172636
Pubmed	An LRP5 receptor with internal deletion in hyperparathyroid tumors with implications for deregulated WNT/beta-catenin signaling.	WNT3 LRP5	1.64e-05	4	58	2	18044981
Pubmed	A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.	KMT2B KMT2A	1.64e-05	4	58	2	23129768
Pubmed	Cross-talk between histone modifications in response to histone deacetylase inhibitors: MLL4 links histone H3 acetylation and histone H3K4 methylation.	KMT2B KMT2A	1.64e-05	4	58	2	17166833
Pubmed	The Foxo1-Inducible Transcriptional Repressor Zfp125 Causes Hepatic Steatosis and Hypercholesterolemia.	ZNF670 INSR	1.64e-05	4	58	2	29320745
Pubmed	Taspase1 orchestrates fetal liver hematopoietic stem cell and vertebrae fates by cleaving TFIIA.	KMT2B KMT2A	1.64e-05	4	58	2	34156981
Pubmed	WDR5 interacts with mixed lineage leukemia (MLL) protein via the histone H3-binding pocket.	KMT2B KMT2A	1.64e-05	4	58	2	18840606
Pubmed	Aven recognition of RNA G-quadruplexes regulates translation of the mixed lineage leukemia protooncogenes.	KMT2B KMT2A	1.64e-05	4	58	2	26267306
Pubmed	The insulin receptor content is increased in breast cancers initiated by three different oncogenes in transgenic mice.	ERBB2 INSR	1.64e-05	4	58	2	9342439
Pubmed	MLL1 is required for PAX7 expression and satellite cell self-renewal in mice.	KMT2B KMT2A	1.64e-05	4	58	2	31534153
Pubmed	Wnt-3, a gene activated by proviral insertion in mouse mammary tumors, is homologous to int-1/Wnt-1 and is normally expressed in mouse embryos and adult brain.	ERBB2 WNT3	1.64e-05	4	58	2	2162045
Pubmed	Neuronal Kmt2a/Mll1 histone methyltransferase is essential for prefrontal synaptic plasticity and working memory.	KMT2B KMT2A	1.64e-05	4	58	2	25834037
Pubmed	FLRG, a new ADAM12-associated protein, modulates osteoclast differentiation.	FSTL3 ADAM12	1.64e-05	4	58	2	15574124
Pubmed	Evolving Catalytic Properties of the MLL Family SET Domain.	KMT2B KMT2A	2.72e-05	5	58	2	26320581
Pubmed	Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation.	KMT2B KMT2A	2.72e-05	5	58	2	25561738
Pubmed	MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia.	KMT2B KMT2A	2.72e-05	5	58	2	28609655
Pubmed	Novel frem1-related mouse phenotypes and evidence of genetic interactions with gata4 and slit3.	FRAS1 SLIT3	2.72e-05	5	58	2	23536828
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	ITGBL1 TRAF3 PHF12 CHRD VWCE ADAM12 WDR59	3.99e-05	560	58	7	21653829
Pubmed	Characterization of mouse Eppin and a gene cluster of similar protease inhibitors on mouse chromosome 2.	WFDC3 WFDC8	4.08e-05	6	58	2	12909348
Pubmed	Two novel transcripts encoding two Ankyrin repeat containing proteins have preponderant expression during the mouse spermatogenesis.	POTEB2 POTEB	4.08e-05	6	58	2	17171436
Pubmed	Cleavage of TFIIA by Taspase1 activates TRF2-specified mammalian male germ cell programs.	KMT2B KMT2A	4.08e-05	6	58	2	24176642
Pubmed	MLL associates specifically with a subset of transcriptionally active target genes.	KMT2B KMT2A	4.08e-05	6	58	2	16199523
Pubmed	Biochemical dissection of Anosmin-1 interaction with FGFR1 and components of the extracellular matrix.	ANOS1 LAMA1	4.08e-05	6	58	2	20874775
Pubmed	Characterization of a first domain of human high glycine-tyrosine and high sulfur keratin-associated protein (KAP) genes on chromosome 21q22.1.	KRTAP10-4 KRTAP10-7 KRTAP10-6	4.16e-05	40	58	3	12359730
Pubmed	Isolation of two novel WNT genes, WNT14 and WNT15, one of which (WNT15) is closely linked to WNT3 on human chromosome 17q21.	ERBB2 WNT3	5.71e-05	7	58	2	9441749
Pubmed	The murine AIDS defective provirus acts as an insertional mutagen in its infected target B cells.	ERBB2 WNT3	5.71e-05	7	58	2	7769664
Pubmed	Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function.	INSR PROC	5.71e-05	7	58	2	28687614
Pubmed	Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice.	ERBB2 WNT3	5.71e-05	7	58	2	7590247
Pubmed	Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.	KMT2B KMT2A	7.60e-05	8	58	2	23130995
Pubmed	NEUROD2 and NEUROD3 genes map to human chromosomes 17q12 and 5q23-q31 and mouse chromosomes 11 and 13, respectively.	ERBB2 WNT3	7.60e-05	8	58	2	9119405
Pubmed	The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.	KMT2B KMT2A	7.60e-05	8	58	2	22266653
Pubmed	Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.	KMT2B KMT2A	9.77e-05	9	58	2	22665483
Pubmed	Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains.	POTEI POTEJ	9.77e-05	9	58	2	16364570
Pubmed	Soluble SORLA Enhances Neurite Outgrowth and Regeneration through Activation of the EGF Receptor/ERK Signaling Axis.	ERBB2 INSR	9.77e-05	9	58	2	32601248
Pubmed	Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression.	KMT2B KMT2A	9.77e-05	9	58	2	16951254
Pubmed	Dynamic expression patterns of ECM molecules in the developing mouse olfactory pathway.	ACAN LAMA1	9.77e-05	9	58	2	18570250
Pubmed	Chromosomal assignment of the heparin-binding cytokine genes MDK and PTN in mouse and man.	ERBB2 WNT3	1.22e-04	10	58	2	7835084
Pubmed	DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.	KMT2B KMT2A	1.22e-04	10	58	2	29276034
Pubmed	Reproduction and immunity-driven natural selection in the human WFDC locus.	WFDC3 WFDC8	1.22e-04	10	58	2	23292442
Pubmed	The regulation and deregulation of Wnt signaling by PARK genes in health and disease.	WNT3 LRP5	1.22e-04	10	58	2	24115276
Pubmed	Aberrantly activated Wnt/β-catenin pathway co-receptors LRP5 and LRP6 regulate osteoblast differentiation in the developing coronal sutures of an Apert syndrome (Fgfr2S252W/+ ) mouse model.	WNT3 LRP5	1.22e-04	10	58	2	32822074
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	FRAS1 LAMA1 SSPOP	1.71e-04	64	58	3	22261194
Pubmed	Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.	KMT2B KMT2A	1.78e-04	12	58	2	27563068
Pubmed	Epithelial Wnt/β-catenin signaling regulates palatal shelf fusion through regulation of Tgfβ3 expression.	WNT3 LRP5	1.78e-04	12	58	2	21185284
Pubmed	Defects of the body plan of mutant embryos lacking Lim1, Otx2 or Hnf3beta activity.	WNT3 CHRD	1.78e-04	12	58	2	11291865
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	ERBB2 TRAF3 KMT2B ADAM18 INSR KMT2A ADAM12	2.07e-04	730	58	7	34857952
Pubmed	Distribution of the mammalian Stat gene family in mouse chromosomes.	ERBB2 WNT3	2.11e-04	13	58	2	8530075
Pubmed	Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.	KMT2B KMT2A	2.11e-04	13	58	2	24619213
Pubmed	Expression of metanephric nephron-patterning genes in differentiating mesonephric tubules.	LAMA1 ADAM12 ITGB8	2.13e-04	69	58	3	21491542
Pubmed	Mutagenic transgene insertion into a region of high gene density and multiple linkage disruptions on mouse chromosome 11.	ERBB2 WNT3	2.46e-04	14	58	2	12438746
Pubmed	A locus on human chromosome 20 contains several genes expressing protease inhibitor domains with homology to whey acidic protein.	WFDC3 WFDC8	2.46e-04	14	58	2	12206714
Pubmed	Sonic hedgehog signaling directly targets Hyaluronic Acid Synthase 2, an essential regulator of phalangeal joint patterning.	ACAN CHRD	2.46e-04	14	58	2	23313125
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ERBB2 INTS5 NSD2 PHF12 SLIT3 G2E3	2.49e-04	529	58	6	14621295
Pubmed	A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis.	LAMA1 ITGB8	2.83e-04	15	58	2	28535372
Pubmed	Identification of a novel actin isoform in hepatocellular carcinoma.	POTEI POTEJ	2.83e-04	15	58	2	16824795
Pubmed	SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53.	KMT2B KMT2A	3.23e-04	16	58	2	23870121
Pubmed	The evolution of a genetic locus encoding small serine proteinase inhibitors.	WFDC3 WFDC8	3.23e-04	16	58	2	15950183
Pubmed	Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects.	FRAS1 LAMA1	3.23e-04	16	58	2	16880404
Pubmed	Hundreds of variants clustered in genomic loci and biological pathways affect human height.	ACAN SLIT3 INSR ZNFX1	3.40e-04	198	58	4	20881960
Pubmed	Mesd encodes an LRP5/6 chaperone essential for specification of mouse embryonic polarity.	WNT3 LRP5	3.66e-04	17	58	2	12581525
Pubmed	Mouse Nkd1, a Wnt antagonist, exhibits oscillatory gene expression in the PSM under the control of Notch signaling.	SLIT3 LAMA1	3.66e-04	17	58	2	15511637
Pubmed	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	NSD2 KMT2A UHRF2	4.08e-04	86	58	3	37253089
Pubmed	A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.	FRAS1 LAMA1	4.11e-04	18	58	2	14730302
Pubmed	Localization of three genes expressed in retina on mouse chromosome 11.	ERBB2 WNT3	4.11e-04	18	58	2	7767000
Pubmed	A comprehensive genetic map of murine chromosome 11 reveals extensive linkage conservation between mouse and human.	ERBB2 WNT3	4.11e-04	18	58	2	2567264
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	ERBB2 NFX1 NFXL1 PHF6 KMT2A UHRF2	4.91e-04	601	58	6	33658012
Pubmed	A novel common variant in DCST2 is associated with length in early life and height in adulthood.	ACAN ZNFX1	5.09e-04	20	58	2	25281659
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	BRIP1 KMT2B NSD2 PHF12 KMT2A UHRF2	5.21e-04	608	58	6	36089195
Pubmed	NRG1 signalling regulates the establishment of Sertoli cell stock in the mouse testis.	ERBB2 LAMA1	5.62e-04	21	58	2	30040984
Pubmed	The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice.	WNT3 LRP5	5.62e-04	21	58	2	15142971
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KMT2B KMT2A	5.62e-04	21	58	2	27626377
Pubmed	Structural basis for activity regulation of MLL family methyltransferases.	KMT2B KMT2A	6.18e-04	22	58	2	26886794
Pubmed	Lamina-associated polypeptide 1 is dispensable for embryonic myogenesis but required for postnatal skeletal muscle growth.	TRAF3 LAMA1	6.18e-04	22	58	2	27798115
Pubmed	Cripto-independent Nodal signaling promotes positioning of the A-P axis in the early mouse embryo.	WNT3 CHRD	6.18e-04	22	58	2	18241853
Pubmed	Expression of the Wnt inhibitor Dickkopf-1 is required for the induction of neural markers in mouse embryonic stem cells differentiating in response to retinoic acid.	WNT3 LRP5	6.18e-04	22	58	2	17064353
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	FRAS1 ACAN SLIT3	6.34e-04	100	58	3	25807483
Pubmed	Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks.	CGRRF1 CBLC UHRF2	7.31e-04	105	58	3	22493164
Pubmed	The absence of Prep1 causes p53-dependent apoptosis of mouse pluripotent epiblast cells.	WNT3 CHRD	7.37e-04	24	58	2	20826531
Pubmed	Dkk1 and Wnt3 interact to control head morphogenesis in the mouse.	WNT3 CHRD	7.37e-04	24	58	2	18403408
Pubmed	Ets2-dependent trophoblast signalling is required for gastrulation progression after primitive streak initiation.	WNT3 CHRD	7.37e-04	24	58	2	23552073
Pubmed	Negative control of Smad activity by ectodermin/Tif1gamma patterns the mammalian embryo.	WNT3 CHRD	7.37e-04	24	58	2	20573697
Pubmed	Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies.	ERBB2 FCGBP KMT2A	7.94e-04	108	58	3	19956635
Pubmed	Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription.	KMT2B KMT2A	8.00e-04	25	58	2	25664857
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	ERBB2 FRAS1 FSTL3 LAMA1 LRP5 NAGPA ADAM12 ITGB8	8.18e-04	1201	58	8	35696571
Pubmed	Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.	KMT2B PHF12 KMT2A	8.37e-04	110	58	3	26841866
Pubmed	Adamts18 modulates the development of the aortic arch and common carotid artery.	ACAN LAMA1	8.66e-04	26	58	2	34189436
Interaction	IGFL3 interactions	FRAS1 INSR LAMA1 LRP5 VWDE	2.25e-06	75	57	5	int:IGFL3
Interaction	LYZL1 interactions	FRAS1 INSR CHRD LRP5 VWDE	2.08e-05	118	57	5	int:LYZL1
Interaction	RSPO2 interactions	KRTAP10-4 KRTAP10-7 KRTAP10-6	4.16e-05	24	57	3	int:RSPO2
Interaction	NAXD interactions	INSR NFXL1 KRTAP10-7 KRTAP10-6	4.85e-05	71	57	4	int:NAXD
Interaction	ADAMTS4 interactions	FRAS1 ACAN INSR LRP5	5.13e-05	72	57	4	int:ADAMTS4
Interaction	NMS interactions	FRAS1 INSR LRP5	8.25e-05	30	57	3	int:NMS
Interaction	DKK1 interactions	WNT3 LRP5 POTEI	1.00e-04	32	57	3	int:DKK1
Interaction	SIRPD interactions	FRAS1 CHRD LRP5 VWDE	1.03e-04	86	57	4	int:SIRPD
Interaction	LCE5A interactions	CHRD ADAM12 KRTAP10-7 KRTAP10-6	1.23e-04	90	57	4	int:LCE5A
Interaction	LCE1F interactions	WFDC3 CHRD KRTAP10-7 KRTAP10-6	1.34e-04	92	57	4	int:LCE1F
Cytoband	21q22.3	KRTAP10-4 KRTAP10-7 KRTAP10-6	5.84e-04	128	58	3	21q22.3
Cytoband	19q13.1	FCGBP KMT2B	2.23e-03	55	58	2	19q13.1
Cytoband	2q21.1	POTEI POTEJ	2.48e-03	58	58	2	2q21.1
Cytoband	20q13.12	WFDC3 WFDC8	2.65e-03	60	58	2	20q13.12
GeneFamily	PHD finger proteins	KMT2B NSD2 PHF12 NFX1 PHF6 KMT2A G2E3 UHRF2	4.20e-11	90	44	8	88
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEI POTEJ POTEB2 POTEB	2.15e-08	13	44	4	685
GeneFamily	WAP four-disulfide core domain containing\|Fibronectin type III domain containing	WFDC3 ANOS1 WFDC8	1.07e-05	18	44	3	361
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2B NSD2 KMT2A	7.63e-05	34	44	3	487
GeneFamily	CD molecules\|Integrin beta subunits	ITGBL1 ITGB8	2.06e-04	9	44	2	1159
GeneFamily	Zinc fingers CXXC-type	KMT2B KMT2A	3.76e-04	12	44	2	136
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ADAM18 ADAM12	1.95e-03	27	44	2	47
GeneFamily	Keratin associated proteins	KRTAP10-4 KRTAP10-7 KRTAP10-6	2.36e-03	109	44	3	619
GeneFamily	Ankyrin repeat domain containing	POTEI POTEJ POTEB2 POTEB	2.79e-03	242	44	4	403
Coexpression	NABA_CORE_MATRISOME	FRAS1 POMZP3 OTOGL ACAN SLIT3 LAMA1 VWCE SSPOP VWDE	5.67e-09	270	56	9	MM17057
Coexpression	NABA_CORE_MATRISOME	FRAS1 ANOS1 POMZP3 ACAN SLIT3 LAMA1 VWCE SSPOP VWDE	6.65e-09	275	56	9	M5884
Coexpression	NABA_ECM_GLYCOPROTEINS	FRAS1 POMZP3 OTOGL SLIT3 LAMA1 VWCE SSPOP VWDE	7.23e-09	191	56	8	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	FRAS1 ANOS1 POMZP3 SLIT3 LAMA1 VWCE SSPOP VWDE	8.85e-09	196	56	8	M3008
Coexpression	NABA_MATRISOME	FRAS1 POMZP3 FSTL3 OTOGL ADAM18 ACAN WNT3 SLIT3 LAMA1 CHRD VWCE ADAM12 SSPOP VWDE	1.82e-08	1008	56	14	MM17056
Coexpression	NABA_MATRISOME	FRAS1 ANOS1 POMZP3 FSTL3 ADAM18 ACAN WNT3 SLIT3 LAMA1 CHRD VWCE ADAM12 SSPOP VWDE	2.27e-08	1026	56	14	M5889
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_TIP\|Cerebellum / BrainAtlas - Mouse McCarroll V32	BRIP1 ADAM18 LAMA1 CHRD ADAM12	1.48e-06	149	58	5	3980fa4f1986a2f164a1826ea043fb71f1d756cd
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 FCGBP LAMA1 ITGB8 RGS12	4.51e-06	187	58	5	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 FCGBP LAMA1 ITGB8 RGS12	4.87e-06	190	58	5	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 FCGBP LAMA1 ITGB8 RGS12	4.87e-06	190	58	5	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	facs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 OTOGL LAMA1 PROC	3.44e-05	141	58	4	4aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCell	facs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 OTOGL LAMA1 PROC	3.44e-05	141	58	4	e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCell	facs-Heart-Unknown-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 OTOGL LAMA1 PROC	3.53e-05	142	58	4	759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FRAS1 OTOGL WNT3 SCN10A	5.91e-05	162	58	4	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 LAMA1 ITGB8 RGS12	9.07e-05	181	58	4	9d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WFDC3 FCGBP CBLC PROC	9.07e-05	181	58	4	a5e770b5b5d57cbac18560828e89f7c96b687743
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WFDC3 FCGBP CBLC PROC	9.07e-05	181	58	4	504b1af1951a7a20ef5db69d84c20630ec64095b
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WFDC3 FCGBP CBLC PROC	9.07e-05	181	58	4	a55ec36d2393f7a376feb42b22aee75dfdf4c383
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANOS1 WNT3 ZNFX1 SSPOP	9.27e-05	182	58	4	52274af3136d4fd4a495f5882618444661421f0f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 LAMA1 ITGB8 RGS12	9.27e-05	182	58	4	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANOS1 WNT3 ZNFX1 SSPOP	9.27e-05	182	58	4	dfde2d9950f445c6c936ac828f7210de87bb45ec
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 OTOGL LAMA1 SSPOP	9.67e-05	184	58	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 OTOGL LAMA1 SSPOP	9.67e-05	184	58	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 OTOGL LAMA1 SSPOP	9.67e-05	184	58	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-2\|TCGA-Kidney / Sample_Type by Project: Shred V9	ITGBL1 ACAN SLIT3 ADAM12	1.01e-04	186	58	4	1e6526fc9e9381b7ace864588cc7bd80194338d6
ToppCell	368C-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	BRIP1 FCGBP SLIT3 ZNF525	1.16e-04	193	58	4	5f5904cec8b2967154ef2eab3c48f51df53aca4a
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	ITGBL1 SLIT3 CHRD ADAM12	1.16e-04	193	58	4	194e7fa00a50cc4e026987b715323d125d79594e
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle-Smooth_muscle_L.2.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FSTL3 ACAN SLIT3 CHRD	1.21e-04	195	58	4	7155cc12cc6a97efd626bbdb95249fb3d7041dcf
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FSTL3 ACAN SLIT3 CHRD	1.21e-04	195	58	4	a52ee3ad6cd317f10b9308450517861ef2e363bb
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Smooth_muscle\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FSTL3 ACAN SLIT3 CHRD	1.21e-04	195	58	4	b3660779f274ca97dd844cf83f62d85ba88cb182
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FSTL3 ACAN SLIT3 CHRD	1.23e-04	196	58	4	8c25fa61c117a60ddd4cbd2f95ae5b66f986a1ec
ToppCell	Parenchymal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FSTL3 ACAN SLIT3 CHRD	1.26e-04	197	58	4	3f078be0b0f5e16edfb6d517beb20ac6178767f0
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	ITGBL1 FRAS1 SLIT3 ADAM12	1.28e-04	198	58	4	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FSTL3 INSR ITGB8 PROC	1.28e-04	198	58	4	be305d89d48c67ce922fa71aaf15e24d00c89ff6
ToppCell	Parenchymal-10x5prime-Stromal-Myofibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FSTL3 ACAN SLIT3 CHRD	1.31e-04	199	58	4	20f760d92c351a1dac4cc0a424c443ea03a179fe
ToppCell	Biopsy_Control_(H.)-Mesenchymal-Smooth_Muscle_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	FSTL3 ACAN SLIT3 CHRD	1.31e-04	199	58	4	31c781a1787e5140fb3f611823cbab4d13d02dfa
ToppCell	Bronchial-10x5prime-Stromal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ITGBL1 FSTL3 SLIT3 CHRD	1.33e-04	200	58	4	5ea12e17f50fefbf5534e487af3392b2fa2d13ad
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_adventitial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ITGBL1 FSTL3 SLIT3 CHRD	1.33e-04	200	58	4	b04831708fa20471a127b87e8db3728b6e729ce8
ToppCell	Tracheal\|World / Cell types per location group and 10X technology with lineage, and cell group designations	FCGBP SLIT3 INSR ITGB8	1.33e-04	200	58	4	682960e28542a3d6c119047cd0131941932cfdea
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ITGBL1 FRAS1 FSTL3 SLIT3	1.33e-04	200	58	4	8c62f05c6042f24287a73fbdf80ff4a56f7ff403
Disease	Stage IV Skin Melanoma	ADAM18 ADAM12	5.41e-05	7	48	2	C1321872
Disease	Shortened QT interval	SCN10A LRP5	1.41e-04	11	48	2	C0151879
Disease	HIV-1 infection, Susceptibility to viral and mycobacterial infections	ADAM18 PROC	5.34e-04	21	48	2	EFO_0000180, Orphanet_391311
Disease	infant body height	ACAN ZNFX1	6.41e-04	23	48	2	EFO_0006785
Disease	Acute monocytic leukemia	BRIP1 KMT2A	8.21e-04	26	48	2	C0023465

Protein segments in the cluster

Peptide	Gene	Start	Entry
AAGCTGPKHSDCLAC	ERBB2	241	P04626
VKIEPCGHLLCSCCL	CBLC	361	Q9ULV8
CGSGPCCTSKCELSI	ADAM18	431	Q9Y3Q7
CCTSKCELSIAGTPC	ADAM18	436	Q9Y3Q7
FHCLCSGKLSESPGC	LINC00528	116	Q8N1L1
CTLKPDAVCAHGLCC	ADAM12	456	O43184
CHCFPCCRGSGKSNV	POTEB2	66	H3BUK9
PGASCHCRLKACECD	PLA2G2C	101	Q5R387
KKCCSNGCGHTCQVP	ANOS1	161	P23352
KHKCTACPQGCLQCS	FRAS1	1046	Q86XX4
CEEGCSKSRPLGCLH	NFXL1	701	Q6ZNB6
HICIAKGDGTPRCSC	LRP5	1226	O75197
CKSSCSLGCDLPETH	IFNA1;	16	P01562
RVCGCLGPKTCSRCH	PDCD2	136	Q16342
VCSKGGSLLCCESCP	NSD2	836	O96028
CEKLCHEGDCGPCSR	NFX1	641	Q12986
CELCLKPGATVGCCL	KMT2B	1641	Q9UMN6
TICKSHGCTAEGLCC	INSR	221	P06213
GTCKETEGHVICLCP	ACAN	2291	P16112
PGHCSRCCCSTKQGN	BRIP1	211	Q9BX63
CASLCCGHGTCIDGI	PROC	101	P04070
SGRGVCVCGKCSCHK	ITGB8	521	P26012
KRCQCCGSSGTHLAC	G2E3	256	Q7L622
AQRGKCCCCREGHSP	LINC01599	51	Q8WXQ3
ILSCVTKDPCHGVTC	FCGBP	1636	Q9Y6R7
HCLPCKDSCDGVECG	FSTL3	91	O95633
CQKPGATVGCCLTSC	KMT2A	1936	Q03164
CVPICCKPVCSGISS	KRTAP10-4	156	P60372
CVPVCCKPVCSGISS	KRTAP10-6	156	P60371
CVPICCKPVCSGISS	KRTAP10-7	156	P60409
LLPCRHTCLCDGCVK	CGRRF1	286	Q99675
ILCSGKGSCHCGKCI	ITGBL1	421	O95965
CVCESCTKPVPLCHD	OTOGL	2006	Q3ZCN5
CGNCSCAHGKLSCSL	SSPOP	3791	A2VEC9
CHCFPCCRGSGKSNV	POTEB	66	A0A0A6YYL3
GCSPCFCSGLSHLCS	LAMA1	1146	P25391
CKCEHHCPCDPKTGN	NAGPA	406	Q9UK23
SCKEGGDLLCCDHCP	PHF12	61	Q96QT6
CHCFPCCRGSGKSNV	POTEJ	66	P0CG39
CHCFPCCRGSGKSNV	POTEI	66	P0CG38
SLLVHCCSAPGGTEC	INTS5	781	Q6P9B9
CAVCTCKGGTGEVHC	CHRD	811	Q9H2X0
SCITCRCGAGVPHCE	CHRD	896	Q9H2X0
CHCRLHSGEKPCKCG	ZNF525	456	Q8N782
LGVSPGCKSCTVCKH	SLIT3	1326	O75094
GCKSCTVCKHGLCRS	SLIT3	1331	O75094
GDPEKKCHSCSCRVC	UHRF2	336	Q96PU4
KCHSCSCRVCGGKHE	UHRF2	341	Q96PU4
LCDGDASCPQGHKCC	WFDC3	136	Q8IUB2
ASCPQGHKCCSTGCG	WFDC3	141	Q8IUB2
GHKCCSTGCGRTCLG	WFDC3	146	Q8IUB2
ECPLVEKCCSHCGLK	WFDC8	221	Q8IUA0
CKNGGECIAPSICHC	VWDE	1526	Q8N2E2
MCSLCHCPGATIGCD	PHF6	81	Q8IWS0
DCPCVVVSCPHKCSV	TRAF3	196	Q13114
HTGEKPCECSECGKC	ZNF549	551	Q6P9A3
TKHCCIHLPDGTSCV	RGS12	961	O14924
TEGCIRHCPCCKLDT	SCN10A	1116	Q9Y5Y9
CCPSCTGCFHSGVVR	VWCE	436	Q96DN2
CKCHGLSGSCEVKTC	WNT3	206	P56703
CTTKCGTILDCGHPC	ZNFX1	1431	Q9P2E3
TQEVCPTGCGCHCLL	WDR59	956	Q6PJI9
ELTHPGEKLCTCGRC	ZNF233	361	A6NK53
ICQCCNKGDCGTPSH	POMZP3	156	Q6PJE2
KPCECSVCGKVFICH	ZNF670	101	Q9BS34