Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP hydrolysis activity

HSP90B1 SPAST RNF213 SRPRA ATP10B CHD2 ABCC6 MOV10L1 SHOC1 MTREX HSPA1A HSPA1B HSPA1L HSPA8 DYNC1H1 RAD54L DNAH11

6.21e-0844115517GO:0016887
GeneOntologyMolecularFunctioninositol 1,4,5-trisphosphate-gated calcium channel activity

ITPR1 ITPR2 ITPR3

4.59e-0731553GO:0005220
GeneOntologyMolecularFunctionprotein-containing complex destabilizing activity

SPAST HSPA1A HSPA1B HSPA8

4.46e-06151554GO:0140776
GeneOntologyMolecularFunctionATP-dependent activity

HSP90B1 SPAST RNF213 SRPRA ATP10B CHD2 ABCC6 MOV10L1 SHOC1 MTREX HSPA1A HSPA1B HSPA1L HSPA8 DYNC1H1 RAD54L DNAH11

5.98e-0661415517GO:0140657
GeneOntologyMolecularFunctionATP-dependent protein disaggregase activity

HSPA1A HSPA1B HSPA8

9.02e-0661553GO:0140545
GeneOntologyMolecularFunctionC3HC4-type RING finger domain binding

HSPA1A HSPA1B HSPA8

9.02e-0661553GO:0055131
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

HSP90B1 SPAST GBP7 LRRK2 RNF213 SRPRA ATP10B CHD2 ABCC6 MOV10L1 SHOC1 MTREX HSPA1A HSPA1B HSPA1L HSPA8 DYNC1H1 RAD54L DNAH11

9.40e-0677515519GO:0017111
GeneOntologyMolecularFunctionATP-dependent protein folding chaperone

HSP90B1 HSPA1A HSPA1B HSPA1L HSPA8

1.40e-05401555GO:0140662
GeneOntologyMolecularFunctionpyrophosphatase activity

HSP90B1 SPAST GBP7 LRRK2 RNF213 SRPRA ATP10B CHD2 ABCC6 MOV10L1 SHOC1 MTREX HSPA1A HSPA1B HSPA1L HSPA8 DYNC1H1 RAD54L DNAH11

2.82e-0583915519GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

HSP90B1 SPAST GBP7 LRRK2 RNF213 SRPRA ATP10B CHD2 ABCC6 MOV10L1 SHOC1 MTREX HSPA1A HSPA1B HSPA1L HSPA8 DYNC1H1 RAD54L DNAH11

2.87e-0584015519GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

HSP90B1 SPAST GBP7 LRRK2 RNF213 SRPRA ATP10B CHD2 ABCC6 MOV10L1 SHOC1 MTREX HSPA1A HSPA1B HSPA1L HSPA8 DYNC1H1 RAD54L DNAH11

2.87e-0584015519GO:0016818
GeneOntologyMolecularFunctioninorganic diphosphate transmembrane transporter activity

ANKH ABCC6

5.99e-0521552GO:0030504
GeneOntologyMolecularFunctionhistone kinase activity

RPS6KA4 ATR RPS6KA5 PRKDC

6.18e-05281554GO:0035173
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1A CACNA1S KCNH8 SLC39A3 ASIC1 TMEM165 KCNIP1 ITPR1 ITPR2 ITPR3 SLC6A2 SLC6A3 SLC9C1

7.12e-0546515513GO:0046873
GeneOntologyMolecularFunctionRNA polymerase II activity

POLR2J3 POLR2J POLR2J2

7.23e-05111553GO:0001055
GeneOntologyMolecularFunctioninositol 1,4,5 trisphosphate binding

ITPR1 ITPR2 ITPR3

1.57e-04141553GO:0070679
GeneOntologyMolecularFunctionnorepinephrine:sodium symporter activity

SLC6A2 SLC6A3

1.79e-0431552GO:0005334
GeneOntologyMolecularFunctiondenatured protein binding

HSPA1A HSPA1B

1.79e-0431552GO:0031249
GeneOntologyMolecularFunctionhistone H2AXS139 kinase activity

ATR PRKDC

1.79e-0431552GO:0035979
GeneOntologyMolecularFunctionhistone H3S28 kinase activity

RPS6KA4 RPS6KA5

1.79e-0431552GO:0044022
GeneOntologyMolecularFunctionprotein folding chaperone

HSP90B1 HSPA1A HSPA1B HSPA1L HSPA8

2.59e-04731555GO:0044183
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

ITPR1 ITPR2 ITPR3

3.44e-04181553GO:0015278
GeneOntologyMolecularFunctionhistone H3S10 kinase activity

RPS6KA4 RPS6KA5

3.56e-0441552GO:0035175
GeneOntologyMolecularFunctiondopamine:sodium symporter activity

SLC6A2 SLC6A3

3.56e-0441552GO:0005330
GeneOntologyMolecularFunctionhistone H2AX kinase activity

ATR PRKDC

5.90e-0451552GO:0141003
GeneOntologyMolecularFunctiondeath receptor agonist activity

HSPA1A HSPA1B

5.90e-0451552GO:0038177
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CACNA1A CACNA1S KCNH8 SLC39A3 ASIC1 TMEM165 KCNIP1 ITPR1 ITPR2 ITPR3 SLC6A2 SLC6A3 SLC9C1 P2RX2

6.84e-0466415514GO:0008324
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

CACNA1A CACNA1S KCNH8 SLC39A3 ASIC1 TMEM165 KCNIP1 ANKH ABCC6 ITPR1 ITPR2 ITPR3 SLC6A2 SLC6A3 SLC9C1

8.42e-0475815515GO:0015318
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1A CACNA1S TMEM165 ITPR1 ITPR2 ITPR3

1.17e-031511556GO:0015085
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

CACNA1A CACNA1S KCNH8 SLC39A3 ASIC1 TMEM165 KCNIP1 ITPR1 ITPR2 ITPR3 SLC6A2 SLC6A3 SLC9C1

1.24e-0362715513GO:0022890
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1A CACNA1S KCNH8 ASIC1 KCNIP1 ITPR1 ITPR2 ITPR3 P2RX2

1.47e-033431559GO:0005261
GeneOntologyMolecularFunctionDNA-directed 5'-3' RNA polymerase activity

POLR2J3 POLR2J POLR2J2

1.60e-03301553GO:0003899
GeneOntologyMolecularFunctionligand-gated calcium channel activity

ITPR1 ITPR2 ITPR3

1.76e-03311553GO:0099604
GeneOntologyMolecularFunction5'-3' RNA polymerase activity

POLR2J3 POLR2J POLR2J2

1.93e-03321553GO:0034062
GeneOntologyMolecularFunctionRNA polymerase activity

POLR2J3 POLR2J POLR2J2

1.93e-03321553GO:0097747
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

ITPR1 ITPR2 ITPR3

2.11e-03331553GO:0005217
GeneOntologyMolecularFunctionprotein serine kinase activity

RPS6KA4 ATR RPS6KA5 LRRK2 STK31 PASK ULK4 PRKDC MAPK4

2.16e-033631559GO:0106310
GeneOntologyMolecularFunctiontumor necrosis factor receptor binding

TRAF3 ERAP1 TNFSF13B

2.50e-03351553GO:0005164
GeneOntologyMolecularFunctionunfolded protein binding

HSP90B1 HSPA1A HSPA1B HSPA1L HSPA8

3.04e-031261555GO:0051082
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1A CACNA1S KCNH8 ASIC1 KCNIP1 ITPR1 ITPR2 ITPR3 SLC9C1 P2RX2

3.17e-0345915510GO:0005216
GeneOntologyMolecularFunctionmagnesium ion binding

RPS6KA4 RPS6KA5 LRRK2 FARSB ATP10B HMGCL MOV10L1

3.22e-032471557GO:0000287
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1A CACNA1S ITPR1 ITPR2 ITPR3

3.36e-031291555GO:0005262
GeneOntologyMolecularFunctiondisordered domain specific binding

EZR HSPA1A HSPA1B

3.42e-03391553GO:0097718
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CACNA1A CACNA1S KCNH8 SLC39A3 ASIC1 TMEM165 KCNIP1 ITPR1 ITPR2 ITPR3 SLC6A2 SLC6A3 SLC9C1 P2RX2

3.57e-0379315514GO:0015075
GeneOntologyMolecularFunctionmonoamine transmembrane transporter activity

SLC6A2 SLC6A3

3.75e-03121552GO:0008504
GeneOntologyMolecularFunctionhistone H3 kinase activity

RPS6KA4 RPS6KA5

3.75e-03121552GO:0140996
GeneOntologyMolecularFunctiongated channel activity

CACNA1A CACNA1S KCNH8 ASIC1 ITPR1 ITPR2 ITPR3 P2RX2

4.64e-033341558GO:0022836
GeneOntologyCellularComponentplatelet dense tubular network membrane

ITPR1 ITPR2 ITPR3

3.31e-0591563GO:0031095
GeneOntologyCellularComponentplatelet dense tubular network

ITPR1 ITPR2 ITPR3

6.44e-05111563GO:0031094
GeneOntologyCellularComponentCOP9 signalosome

DOCK7 HSPA1A HSPA1B HSPA1L

1.81e-04381564GO:0008180
GeneOntologyCellularComponentRNA polymerase II, core complex

POLR2J3 POLR2J POLR2J2

2.57e-04171563GO:0005665
GeneOntologyCellularComponentsarcoplasmic reticulum

CACNA1S HSP90B1 ITPR1 ITPR2 ITPR3

5.17e-04881565GO:0016529
GeneOntologyCellularComponentcell body

CACNA1A EZR PSD2 LRRK2 KCNIP1 TIAM2 ITPR1 ITPR3 SLC6A2 SLC6A3 P2RX2 MMP3 HSPA1B HSPA1L HSPA8 DYNC1H1 SYNCRIP

5.89e-0492915617GO:0044297
DomainInsP3_rcpt-bd

ITPR1 ITPR2 ITPR3

5.50e-0731543IPR000493
DomainRNA_POL_L_13KD

POLR2J3 POLR2J POLR2J2

2.19e-0641543PS01154
DomainRNA_pol_Rpb11_13-16kDa_CS

POLR2J3 POLR2J POLR2J2

2.19e-0641543IPR008193
DomainHSP70

HSPA1A HSPA1B HSPA1L HSPA8

7.49e-06161544PF00012
DomainHSP70_2

HSPA1A HSPA1B HSPA1L HSPA8

9.73e-06171544PS00329
DomainHSP70_1

HSPA1A HSPA1B HSPA1L HSPA8

9.73e-06171544PS00297
DomainHSP70_3

HSPA1A HSPA1B HSPA1L HSPA8

9.73e-06171544PS01036
DomainRIH_assoc-dom

ITPR1 ITPR2 ITPR3

1.08e-0561543IPR013662
DomainIns145_P3_rec

ITPR1 ITPR2 ITPR3

1.08e-0561543PF08709
DomainRIH_assoc

ITPR1 ITPR2 ITPR3

1.08e-0561543PF08454
DomainRBP11-like_dimer

POLR2J3 POLR2J POLR2J2

1.08e-0561543IPR009025
DomainRIH_dom

ITPR1 ITPR2 ITPR3

1.08e-0561543IPR000699
DomainIns145_P3_rcpt

ITPR1 ITPR2 ITPR3

1.08e-0561543IPR014821
DomainRyanodine_recept-rel

ITPR1 ITPR2 ITPR3

1.08e-0561543IPR015925
Domain-

ITPR1 ITPR2 ITPR3

1.08e-05615431.25.10.30
DomainRYDR_ITPR

ITPR1 ITPR2 ITPR3

1.08e-0561543PF01365
DomainRNA_pol_L

POLR2J3 POLR2J POLR2J2

1.08e-0561543PF01193
DomainHsp_70_fam

HSPA1A HSPA1B HSPA1L HSPA8

1.24e-05181544IPR013126
DomainPentatricopeptide_repeat

ASZ1 NCAPG2 PIP5K1B PRKDC

3.48e-05231544IPR002885
DomainIon_trans_dom

CACNA1A CACNA1S KCNH8 ITPR1 ITPR2 ITPR3 SLC9C1

4.45e-051141547IPR005821
DomainIon_trans

CACNA1A CACNA1S KCNH8 ITPR1 ITPR2 ITPR3 SLC9C1

4.45e-051141547PF00520
DomainHEAT

ATR HEATR1 NCAPG2 NCAPD2 PRKDC

4.59e-05481545PF02985
DomainMIR

ITPR1 ITPR2 ITPR3

6.32e-05101543PF02815
DomainMIR_motif

ITPR1 ITPR2 ITPR3

6.32e-05101543IPR016093
DomainMIR

ITPR1 ITPR2 ITPR3

6.32e-05101543PS50919
DomainMIR

ITPR1 ITPR2 ITPR3

6.32e-05101543SM00472
Domain-

HSPA1A HSPA1L HSPA8

1.15e-041215432.60.34.10
DomainHSP70_peptide-bd

HSPA1A HSPA1L HSPA8

1.15e-04121543IPR029047
DomainHEAT

ATR HEATR1 NCAPG2 NCAPD2 PRKDC

1.15e-04581545IPR000357
Domain-

HSPA1A HSPA1L HSPA8

1.48e-041315431.20.1270.10
DomainHeat_shock_70_CS

HSPA1A HSPA1L HSPA8

1.48e-04131543IPR018181
DomainHSP70_C

HSPA1A HSPA1L HSPA8

1.48e-04131543IPR029048
DomainRNA_pol_L_2

POLR2J POLR2J2

2.02e-0431542PF13656
DomainHEAT_REPEAT

ATR HEATR1 NCAPG2 ULK4 PRKDC

2.81e-04701545PS50077
DomainEz/rad/moesin-like

EZR FRMD4B EPB41

6.56e-04211543IPR000798
DomainFATC

ATR PRKDC

6.65e-0451542PF02260
DomainKRAB

ZNF234 ZNF155 ZNF223 ZNF224 ZNF226 ZNF112 ZNF230 ZNF235 ZNF284 ZNF222

7.90e-0435815410PS50805
DomainKRAB

ZNF234 ZNF155 ZNF223 ZNF224 ZNF226 ZNF112 ZNF230 ZNF235 ZNF284 ZNF222

7.90e-0435815410PF01352
DomainFERM_CS

EZR FRMD4B EPB41

9.80e-04241543IPR019747
DomainFAT

ATR PRKDC

9.91e-0461542PS51189
DomainFATC

ATR PRKDC

9.91e-0461542PS51190
DomainFAT

ATR PRKDC

9.91e-0461542PF02259
DomainPIK-rel_kinase_FAT

ATR PRKDC

9.91e-0461542IPR003151
DomainFATC_dom

ATR PRKDC

9.91e-0461542IPR003152
DomainRibosomal_S6_kinase_II

RPS6KA4 RPS6KA5

9.91e-0461542IPR016239
DomainPIK_FAT

ATR PRKDC

9.91e-0461542IPR014009
DomainFATC

ATR PRKDC

9.91e-0461542SM01343
DomainKRAB

ZNF234 ZNF155 ZNF223 ZNF224 ZNF226 ZNF112 ZNF230 ZNF235 ZNF284 ZNF222

9.94e-0436915410SM00349
DomainKRAB

ZNF234 ZNF155 ZNF223 ZNF224 ZNF226 ZNF112 ZNF230 ZNF235 ZNF284 ZNF222

1.01e-0337015410IPR001909
DomainFERM_C

EZR FRMD4B EPB41

1.24e-03261543PF09380
DomainAAA

SPAST RNF213 SRPRA ABCC6 DYNC1H1 DNAH11

1.25e-031441546SM00382
DomainAAA+_ATPase

SPAST RNF213 SRPRA ABCC6 DYNC1H1 DNAH11

1.25e-031441546IPR003593
Domain-

SPAST GBP7 LRRK2 RNF213 SRPRA CHD2 ABCC6 SBNO1 MOV10L1 MTREX DYNC1H1 CARD14 RAD54L NLRP13 DNAH11

1.30e-03746154153.40.50.300
DomainCa_chan_IQ

CACNA1A CACNA1S

1.38e-0371542SM01062
DomainCa_chan_IQ

CACNA1A CACNA1S

1.38e-0371542PF08763
DomainVDCC_a1su_IQ

CACNA1A CACNA1S

1.38e-0371542IPR014873
DomainGPHH

CACNA1A CACNA1S

1.38e-0371542PF16905
DomainGPHH_dom

CACNA1A CACNA1S

1.38e-0371542IPR031649
DomainFERM_PH-like_C

EZR FRMD4B EPB41

1.39e-03271543IPR018980
DomainFERM_C

EZR FRMD4B EPB41

1.39e-03271543SM01196
DomainP-loop_NTPase

MAGI1 SPAST GBP7 LRRK2 RNF213 SRPRA CHD2 ABCC6 SBNO1 MOV10L1 MTREX DYNC1H1 CARD14 RAD54L NLRP13 DNAH11

1.74e-0384815416IPR027417
DomainDHC_N1

DYNC1H1 DNAH11

1.83e-0381542PF08385
DomainDynein_heavy_dom-1

DYNC1H1 DNAH11

1.83e-0381542IPR013594
DomainARM-type_fold

ATR LRRK2 HEATR1 NCAPG2 ITPR1 ITPR2 NCAPD2 ULK4 PRKDC

2.04e-033391549IPR016024
Domain-

ATR LRRK2 HEATR1 NCAPG2 NCAPD2 ULK4 PRKDC

2.48e-0322215471.25.10.10
DomainFERM_N

EZR FRMD4B EPB41

2.50e-03331543IPR018979
DomainFERM_N

EZR FRMD4B EPB41

2.50e-03331543PF09379
DomainEF-hand_8

CAPN1 KCNIP1 MICU2

2.73e-03341543PF13833
DomainPAS_9

KCNH8 PASK

2.91e-03101542PF13426
DomainVDCCAlpha1

CACNA1A CACNA1S

2.91e-03101542IPR002077
DomainDHR-1_domain

DOCK4 DOCK7

3.54e-03111542IPR027007
DomainDHR_2

DOCK4 DOCK7

3.54e-03111542PS51651
DomainDHR_1

DOCK4 DOCK7

3.54e-03111542PS51650
DomainDHR-2

DOCK4 DOCK7

3.54e-03111542PF06920
DomainDOCK

DOCK4 DOCK7

3.54e-03111542IPR026791
DomainDOCK_C

DOCK4 DOCK7

3.54e-03111542IPR010703
DomainDOCK-C2

DOCK4 DOCK7

3.54e-03111542PF14429
DomainDHR-2

DOCK4 DOCK7

3.54e-03111542IPR027357
DomainDynein_heavy_chain_D4_dom

DYNC1H1 DNAH11

5.76e-03141542IPR024317
DomainDynein_HC_stalk

DYNC1H1 DNAH11

5.76e-03141542IPR024743
DomainDynein_heavy_dom-2

DYNC1H1 DNAH11

5.76e-03141542IPR013602
DomainDHC_N2

DYNC1H1 DNAH11

5.76e-03141542PF08393
DomainATPase_dyneun-rel_AAA

DYNC1H1 DNAH11

5.76e-03141542IPR011704
DomainMT

DYNC1H1 DNAH11

5.76e-03141542PF12777
DomainAAA_8

DYNC1H1 DNAH11

5.76e-03141542PF12780
DomainAAA_5

DYNC1H1 DNAH11

5.76e-03141542PF07728
DomainFERM_M

EZR FRMD4B EPB41

6.44e-03461543PF00373
DomainDHC_fam

DYNC1H1 DNAH11

6.61e-03151542IPR026983
DomainDynein_heavy

DYNC1H1 DNAH11

6.61e-03151542PF03028
DomainPI3/4_kinase_CS

ATR PRKDC

6.61e-03151542IPR018936
DomainPept_M10A_Zn_BS

MMP3 MMP8

6.61e-03151542IPR021158
DomainDynein_heavy_dom

DYNC1H1 DNAH11

6.61e-03151542IPR004273
DomainWW

MAGI1 CMTR1 HECW2

6.84e-03471543PF00397
DomainARM-like

ATR LRRK2 HEATR1 NCAPG2 NCAPD2 ULK4 PRKDC

7.17e-032701547IPR011989
DomainWW

MAGI1 CMTR1 HECW2

7.25e-03481543SM00456
Domain-

ATR PRKDC

7.51e-031615421.10.1070.11
DomainPI3Kc

ATR PRKDC

7.51e-03161542SM00146
Domain-

EZR FRMD4B EPB41

7.68e-034915431.20.80.10
DomainFERM_central

EZR FRMD4B EPB41

7.68e-03491543IPR019748
DomainFERM_domain

EZR FRMD4B EPB41

7.68e-03491543IPR000299
PathwayREACTOME_ATTENUATION_PHASE

HSPA1A HSPA1B HSPA1L HSPA8

4.22e-06131274MM14952
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR1 ITPR2 ITPR3 P2RX2

4.22e-06131274MM14553
PathwayREACTOME_HSP90_CHAPERONE_CYCLE_FOR_STEROID_HORMONE_RECEPTORS_SHR_IN_THE_PRESENCE_OF_LIGAND

HSPA1A HSPA1B HSPA1L HSPA8 FKBP5 DYNC1H1

6.89e-06521276MM14949
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_MGLUR1_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

7.05e-0651273M49000
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR1 ITPR2 ITPR3 P2RX2

1.05e-05161274M26945
PathwayREACTOME_HSP90_CHAPERONE_CYCLE_FOR_STEROID_HORMONE_RECEPTORS_SHR_IN_THE_PRESENCE_OF_LIGAND

HSPA1A HSPA1B HSPA1L HSPA8 FKBP5 DYNC1H1

1.18e-05571276M27251
PathwayKEGG_MEDICUS_REFERENCE_CA2_PLCD_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

1.40e-0561273M47960
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

HSPA1A HSPA1B HSPA1L HSPA8

4.87e-05231274MM14953
PathwayKEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

5.77e-0591273M47852
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

8.18e-05101273M47661
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

ITPR1 ITPR2 ITPR3 P2RX2

9.39e-05271274MM15053
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

ATR NUP205 HSPA1A HSPA1B HSPA1L HSPA8

9.50e-05821276M27250
PathwayREACTOME_ATTENUATION_PHASE

HSPA1A HSPA1B HSPA1L HSPA8

1.09e-04281274M27254
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

ITPR1 ITPR2 ITPR3 P2RX2

1.09e-04281274M924
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

1.12e-04111273M49033
PathwayREACTOME_CLEC7A_DECTIN_1_INDUCES_NFAT_ACTIVATION

ITPR1 ITPR2 ITPR3

1.12e-04111273M27466
PathwayKEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

1.91e-04131273M47656
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

1.91e-04131273M47696
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

1.91e-04131273M47751
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

CACNA1A CACNA1S HTR4 ADCY9 ITPR1 ITPR2 ITPR3 P2RX2

2.06e-041781278M2890
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

ATR NUP205 HSPA1A HSPA1B HSPA1L HSPA8

2.99e-041011276M27253
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

HSPA1A HSPA1B HSPA1L HSPA8

3.66e-04381274M27255
PathwayWP_MAPK_SIGNALING

CACNA1A CACNA1S RPS6KA4 RPS6KA5 LRRK2 HSPA1A HSPA1B HSPA1L HSPA8

3.84e-042461279M39597
PathwayWP_PARKINUBIQUITIN_PROTEASOMAL_SYSTEM_PATHWAY

HSPA1A HSPA1B HSPA1L HSPA8 FBXW7

4.44e-04711275M39690
PathwayREACTOME_DAG_AND_IP3_SIGNALING

ADCY9 ITPR1 ITPR2 ITPR3

4.92e-04411274M512
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

NUP205 HSPA1A HSPA1B HSPA1L HSPA8

5.05e-04731275MM14948
PathwayWP_ALZHEIMERS_DISEASE

CACNA1S CAPN1 ITPR1 ITPR2 ITPR3

5.37e-04741275MM15962
PathwayREACTOME_VEGFR2_MEDIATED_CELL_PROLIFERATION

ITPR1 ITPR2 ITPR3

6.23e-04191273M27423
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

6.23e-04191273M47760
PathwayKEGG_MEDICUS_REFERENCE_TCR_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

6.23e-04191273M47733
PathwayKEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

7.28e-04201273M47688
PathwayREACTOME_FBXW7_MUTANTS_AND_NOTCH1_IN_CANCER

SKP1 FBXW7

7.91e-0451272M27197
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

8.43e-04211273M47689
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

9.70e-04221273M47690
PathwayKEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

9.70e-04221273M47675
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

1.11e-03231273M47676
PathwayREACTOME_G_PROTEIN_MEDIATED_EVENTS

ADCY9 ITPR1 ITPR2 ITPR3

1.40e-03541274M26911
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

ITPR1 ITPR2 ITPR3

1.42e-03251273MM14511
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

NUP205 HSPA1A HSPA1B HSPA1L HSPA8

1.44e-03921275MM14951
Pubmed

Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.

ZNF234 ZNF155 ZNF223 ZNF224 ZNF226 ZNF112 ZNF230 ZNF235 ZNF284 ZNF222

4.67e-19201571012743021
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

HSP90B1 TRAF3 FARSB RNF213 SRPRA HEATR1 FAM98B SKP1 NCAPG2 RRP1 ITPR1 NUP205 ITPR2 ITPR3 FANCD2 MYOF TNFSF13B VPS35L NCAPD2 DOCK7 PRKDC MTREX ADGRL2 COG4 FKBP5 DYNC1H1 SYNCRIP

3.36e-1014401572730833792
Pubmed

Association analysis of heat shock protein 70 gene polymorphisms in schizophrenia.

HSPA1A HSPA1B HSPA1L HSPA8

4.00e-104157418299791
Pubmed

A GO catalogue of human DNA-binding transcription factors.

ZNF234 ZNF155 ZNF781 ZNF223 ZNF230 ZNF235 ZNF222

7.89e-1042157734673265
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

EZR HSP90B1 INTU ZSWIM5 TRO SLC44A2 ATP10B CHD2 HMGCL ZNF318 HEATR1 FAM98B STK31 TASOR2 NUP205 SBNO1 NCAPD2 PLXNA4 DLAT PRKDC CADPS2 SKAP2 HSPA1L HSPA8 ERICH6 SYNCRIP

1.69e-0914421572635575683
Pubmed

HDJC9, a novel human type C DnaJ/HSP40 member interacts with and cochaperones HSP70 through the J domain.

HSPA1A HSPA1B HSPA1L HSPA8

1.99e-095157417182002
Pubmed

Genetic aspects of the hsp70 multigene family in vertebrates.

HSPA1A HSPA1B HSPA1L HSPA8

5.95e-09615747988674
Pubmed

Phosphorylation and binding partner analysis of the TSC1-TSC2 complex.

DOCK7 HSPA1A HSPA1B HSPA8

5.95e-096157415963462
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

CAPN1 CHD2 ZNF318 HEATR1 RRP1 TASOR2 NUP205 ITPR3 MCM3AP NCAPD2 DOCK7 DLAT ATIC PRKDC MTREX DYNC1H1 SYNCRIP

7.82e-096531571722586326
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

EZR HSP90B1 RPS6KA4 CAPN1 FARSB SRPRA HEATR1 SKP1 RRP1 TASOR2 NUP205 ITPR2 ITPR3 MRPL39 MYOF DOCK7 PRKDC MTREX MICU2 HSPA1B HSPA8 DYNC1H1 SYNCRIP

1.25e-0812571572336526897
Pubmed

Defining the membrane proteome of NK cells.

EZR HSP90B1 ERAP1 FARSB RNF213 HEATR1 NCAPG2 ITPR1 NUP205 ITPR2 ITPR3 PAPOLG CD37 NCAPD2 PARP9 ATIC PRKDC HSPA8 FKBP5 DYNC1H1 SYNCRIP

7.70e-0811681572119946888
Pubmed

Dependence of leucine-rich repeat kinase 2 (LRRK2) kinase activity on dimerization.

LRRK2 PRKDC HSPA8 DYNC1H1

8.22e-0810157419826009
Pubmed

Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins.

ITPR1 ITPR2 ITPR3

9.02e-083157310874040
Pubmed

Analysis of heat shock protein 70 gene polymorphisms Mexican patients with idiopathic pulmonary fibrosis.

HSPA1A HSPA1B HSPA1L

9.02e-083157326496868
Pubmed

Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.

ITPR1 ITPR2 ITPR3

9.02e-083157320395455
Pubmed

Genetic polymorphisms of HSP70 in age-related cataract.

HSPA1A HSPA1B HSPA1L

9.02e-083157323666708
Pubmed

Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.

ITPR1 ITPR2 ITPR3

9.02e-083157317437169
Pubmed

Interacting contribution of the five polymorphisms in three genes of Hsp70 family to essential hypertension in Uygur ethnicity.

HSPA1A HSPA1B HSPA1L

9.02e-083157319085089
Pubmed

Heat shock protein 70 gene polymorphisms in Mexican patients with spondyloarthropathies.

HSPA1A HSPA1B HSPA1L

9.02e-083157311779758
Pubmed

Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.

ITPR1 ITPR2 ITPR3

9.02e-083157318547250
Pubmed

Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population.

ITPR1 ITPR2 ITPR3

9.02e-083157336350267
Pubmed

The versatility and universality of calcium signalling.

ITPR1 ITPR2 ITPR3

9.02e-083157311413485
Pubmed

The impact of heat shock protein 70 gene variations on clinical presentation and outcome in schizophrenic inpatients.

HSPA1A HSPA1B HSPA1L

9.02e-083157319439993
Pubmed

Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2 ITPR3

9.02e-083157326009177
Pubmed

Is preeclampsia associated with higher frequency of HSP70 gene polymorphisms?

HSPA1A HSPA1B HSPA1L

9.02e-083157316202503
Pubmed

Heat-shock protein-70 genes and response to antidepressants in major depression.

HSPA1A HSPA1B HSPA1L

9.02e-083157317428599
Pubmed

Polymorphisms of heat shock protein 70 gene (HSPA1A, HSPA1B and HSPA1L) and schizophrenia.

HSPA1A HSPA1B HSPA1L

9.02e-083157315963589
Pubmed

Heat shock protein 70 gene polymorphisms in sudden sensorineural hearing loss.

HSPA1A HSPA1B HSPA1L

9.02e-083157322922572
Pubmed

Receptor-activated single channels in intact human platelets.

ITPR1 ITPR2 ITPR3

9.02e-08315731693919
Pubmed

Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.

ITPR1 ITPR2 ITPR3

9.02e-083157323955339
Pubmed

Heat shock protein 70 gene polymorphisms in Han nationality of China with chronic obstructive pulmonary diseases.

HSPA1A HSPA1B HSPA1L

9.02e-083157315165109
Pubmed

Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.

ITPR1 ITPR2 ITPR3

9.02e-083157331979185
Pubmed

Electrophoretic and immunocytochemical analysis of Hsp72 and Hsp73 expression in heat-stressed mouse testis and epididymis.

HSPA1A HSPA1B HSPA8

9.02e-083157323352621
Pubmed

Tsg101 regulates PI(4,5)P2/Ca(2+) signaling for HIV-1 Gag assembly.

ITPR1 ITPR2 ITPR3

9.02e-083157324904548
Pubmed

A prospective evaluation of the heat shock protein 70 gene polymorphisms and the risk of stroke.

HSPA1A HSPA1B HSPA1L

9.02e-083157312008944
Pubmed

Stored of Hsp72/Hsp73 in germinal vesicle-stage mouse oocytes.

HSPA1A HSPA1B HSPA8

9.02e-083157315129916
Pubmed

Association of hsp70-2 and hsp-hom gene polymorphisms with risk of acute high-altitude illness in a Chinese population.

HSPA1A HSPA1B HSPA1L

9.02e-083157316333988
Pubmed

Differential distribution of inositol trisphosphate receptor isoforms in mouse oocytes.

ITPR1 ITPR2 ITPR3

9.02e-08315739858485
Pubmed

Heat shock protein 70 gene polymorphisms are associated with paranoid schizophrenia in the Polish population.

HSPA1A HSPA1B HSPA1L

9.02e-083157323893339
Pubmed

Interactive association of heat shock protein 70 genes variants with natural longevity in Xinjiang Hetian Uygur ethnicity.

HSPA1A HSPA1B HSPA1L

9.02e-083157319840767
Pubmed

Expression of inositol 1,4,5-trisphosphate receptors in mouse oocytes and early embryos: the type I isoform is upregulated in oocytes and downregulated after fertilization.

ITPR1 ITPR2 ITPR3

9.02e-08315739808793
Pubmed

Chromosomal location of human genes encoding major heat-shock protein HSP70.

HSPA1A HSPA1B HSPA1L

9.02e-08315733470951
Pubmed

Heat-shock protein gene polymorphisms and the risk of nephropathy in patients with Type 2 diabetes.

HSPA1A HSPA1B HSPA1L

9.02e-083157318518860
Pubmed

Genetic interaction of Hsp70 family genes polymorphisms with high-altitude pulmonary edema among Chinese railway constructors at altitudes exceeding 4000 meters.

HSPA1A HSPA1B HSPA1L

9.02e-083157319351530
Pubmed

Type 2 and type 3 inositol 1,4,5-trisphosphate (IP3) receptors promote the differentiation of granule cell precursors in the postnatal cerebellum.

ITPR1 ITPR2 ITPR3

9.02e-083157318194433
Pubmed

IP3 receptors regulate vascular smooth muscle contractility and hypertension.

ITPR1 ITPR2 ITPR3

9.02e-083157327777977
Pubmed

Localization of a human heat-shock HSP 70 gene sequence to chromosome 6 and detection of two other loci by somatic-cell hybrid and restriction fragment length polymorphism analysis.

HSPA1A HSPA1B HSPA1L

9.02e-08315732880793
Pubmed

HLA complex-linked heat shock protein genes and childhood acute lymphoblastic leukemia susceptibility.

HSPA1A HSPA1B HSPA1L

9.02e-083157320012387
Pubmed

Analysis of the heat shock protein 70 (HSP70) genetic variants in nonsegmental vitiligo patients.

HSPA1A HSPA1B HSPA1L

9.02e-083157336345598
Pubmed

Differential inositol 1,4,5-trisphosphate receptor signaling in a neuronal cell line.

ITPR1 ITPR2 ITPR3

9.02e-083157317581770
Pubmed

Functional analysis of HSPA1A and HSPA8 in parturition.

HSPA1A HSPA1B HSPA8

9.02e-083157328025138
Pubmed

Predominant role of type 1 IP3 receptor in aortic vascular muscle contraction.

ITPR1 ITPR2 ITPR3

9.02e-083157318241669
Pubmed

Structure and expression of the three MHC-linked HSP70 genes.

HSPA1A HSPA1B HSPA1L

9.02e-08315731700760
Pubmed

Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca2+ mobilization.

ITPR1 ITPR2 ITPR3

9.02e-083157319068129
Pubmed

Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2 ITPR3

9.02e-083157317327232
Pubmed

Heat shock protein 70 gene polymorphism in Japanese patients with multiple sclerosis.

HSPA1A HSPA1B HSPA1L

9.02e-083157311696222
Pubmed

Nuclear inositol 1,4,5-trisphosphate receptors regulate local Ca2+ transients and modulate cAMP response element binding protein phosphorylation.

ITPR1 ITPR2 ITPR3

9.02e-083157316014380
Pubmed

Knockdown of the type 2 and 3 inositol 1,4,5-trisphosphate receptors suppresses muscarinic antinociception in mice.

ITPR1 ITPR2 ITPR3

9.02e-083157317890015
Pubmed

Inositol 1, 4, 5-trisphosphate receptors and human left ventricular myocytes.

ITPR1 ITPR2 ITPR3

9.02e-083157323983250
Pubmed

The relationship between three heat shock protein 70 gene polymorphisms and susceptibility to lung cancer.

HSPA1A HSPA1B HSPA1L

9.02e-083157320704535
Pubmed

Anti-inflammatory heat shock protein 70 genes are positively associated with human survival.

HSPA1A HSPA1B HSPA1L

9.02e-083157320388090
Pubmed

Activation of the inositol (1,4,5)-triphosphate calcium gate receptor is required for HIV-1 Gag release.

ITPR1 ITPR2 ITPR3

9.02e-083157320427533
Pubmed

Human major histocompatibility complex contains genes for the major heat shock protein HSP70.

HSPA1A HSPA1B HSPA1L

9.02e-08315732538825
Pubmed

Analysis of heat-shock protein 70 gene polymorphisms and the risk of Parkinson's disease.

HSPA1A HSPA1B HSPA1L

9.02e-083157314605873
Pubmed

Genomic structure of the spermatid-specific hsp70 homolog gene located in the class III region of the major histocompatibility complex of mouse and man.

HSPA1A HSPA1B HSPA1L

9.02e-08315739685725
Pubmed

Effects of polymorphisms of heat shock protein 70 gene on ischemic stroke, and interaction with smoking in China.

HSPA1A HSPA1B HSPA1L

9.02e-083157317582394
Pubmed

Polymorphisms of heat shock protein 70 genes (HSPA1A, HSPA1B and HSPA1L) and susceptibility of noise-induced hearing loss in a Chinese population: A case-control study.

HSPA1A HSPA1B HSPA1L

9.02e-083157328182740
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

EZR MAGI1 HSP90B1 TMEM165 FARSB SRPRA ADCY9 NCAPD2 DOCK7 PRKDC ADGRL2 HSPA1B HSPA8 DYNC1H1 EPB41 SYNCRIP

1.52e-077081571639231216
Pubmed

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.

EZR HSP90B1 ZNF781 FARSB ZNF235 NCAPG2 DLAT ATIC MTREX HSPA1A HSPA1B HSPA8 SYNCRIP

1.55e-074511571336168627
Pubmed

A CASPR1-ATP1B3 protein interaction modulates plasma membrane localization of Na+/K+-ATPase in brain microvascular endothelial cells.

HSPA1A HSPA1B HSPA1L HSPA8

2.77e-0713157430792309
Pubmed

UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome.

HSPA1A HSPA1B HSPA1L HSPA8

2.77e-0713157427477512
Pubmed

Loss of IP3R-dependent Ca2+ signalling in thymocytes leads to aberrant development and acute lymphoblastic leukemia.

ITPR1 ITPR2 ITPR3

3.60e-074157325215520
Pubmed

Variations in HSP70 genes associated with noise-induced hearing loss in two independent populations.

HSPA1A HSPA1B HSPA1L

3.60e-074157318813331
Pubmed

[New genes on human chromosome 7: bioinformatic analysis of a gene cluster from the POLR2J family].

POLR2J3 POLR2J POLR2J2

3.60e-074157315586814
Pubmed

Alternative splice variants of hTrp4 differentially interact with the C-terminal portion of the inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2 ITPR3

3.60e-074157311163362
Pubmed

A human RNA polymerase II subunit is encoded by a recently generated multigene family.

POLR2J3 POLR2J POLR2J2

3.60e-074157311747469
Pubmed

Inositol 1, 4, 5-trisphosphate receptor interacts with the SNARE domain of syntaxin 1B.

ITPR1 ITPR2 ITPR3

3.60e-074157321424589
Pubmed

[Effect of HSP70 gene polymorphism on genetic susceptibility of pneumoconiosis of coal worker].

HSPA1A HSPA1B HSPA1L

3.60e-074157320568452
Pubmed

Loss of IP3 Receptor-Mediated Ca2+ Release in Mouse B Cells Results in Abnormal B Cell Development and Function.

ITPR1 ITPR2 ITPR3

3.60e-074157328615414
Pubmed

Distinct localization and function of (1,4,5)IP(3) receptor subtypes and the (1,3,4,5)IP(4) receptor GAP1(IP4BP) in highly purified human platelet membranes.

ITPR1 ITPR2 ITPR3

3.60e-074157310828023
Pubmed

Delayed temporal increase of hepatic Hsp70 in ApoE knockout mice after prenatal arsenic exposure.

HSPA1A HSPA1B HSPA8

3.60e-074157322956628
Pubmed

Upregulation of the constitutively expressed HSC70 by KLF4.

HSPA1A HSPA1B HSPA8

3.60e-074157318379898
Pubmed

Polymorphisms in the Hsp70 gene locus are genetically associated with systemic lupus erythematosus.

HSPA1A HSPA1B HSPA1L

3.60e-074157320498198
Pubmed

IP3R-mediated Ca2+ signals govern hematopoietic and cardiac divergence of Flk1+ cells via the calcineurin-NFATc3-Etv2 pathway.

ITPR1 ITPR2 ITPR3

3.60e-074157328419336
Pubmed

IP3R-mediated Ca2+ signaling controls B cell proliferation through metabolic reprogramming.

ITPR1 ITPR2 ITPR3

3.60e-074157335494252
Pubmed

HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.

HSP90B1 CAPN1 FARSB HEATR1 FAM98B NUP205 FANCD2 NCAPD2 PRKDC MTREX HSPA1A HSPA1B HSPA8 DYNC1H1

3.60e-075711571437167062
Pubmed

Effects of beta-estradiol and bisphenol A on heat shock protein levels and localization in the mouse uterus are antagonized by the antiestrogen ICI 182,780.

HSP90B1 HSPA1A HSPA1B

8.97e-075157311568360
Pubmed

A DnaJ protein, apobec-1-binding protein-2, modulates apolipoprotein B mRNA editing.

HSPA1A HSPA1B HSPA8

8.97e-075157311584023
Pubmed

Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration.

HSPA1A HSPA1B HSPA8

8.97e-075157316906134
Pubmed

A susceptibility gene for alveolar lung tumors in the mouse maps between Hsp70.3 and G7 within the H2 complex.

HSPA1A HSPA1B HSPA1L

8.97e-07515737806281
Pubmed

Polymorphisms in TNF and HSP-70 show a significant association with gastric cancer and duodenal ulcer.

HSPA1A HSPA1B HSPA1L

8.97e-075157319626584
Pubmed

InsP₃receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences.

ITPR1 ITPR2 ITPR3

8.97e-075157321568942
Pubmed

The thymocyte-specific MAR binding protein, SATB1, interacts in vitro with a novel variant of DNA-directed RNA polymerase II, subunit 11.

POLR2J3 POLR2J POLR2J2

8.97e-075157312036295
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CFAP47 RNF213 SRPRA CHD2 ZNF226 NUP205 ITPR2 HECW2 MCM3AP PLXNA4 ATIC PRKDC CFAP57 HSPA8 DYNC1H1

1.38e-067361571529676528
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

ITPR1 ITPR2 ITPR3

1.79e-066157323463619
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

ITPR1 ITPR2 ITPR3

1.79e-066157325966694
Pubmed

New microsatellite size variants as markers for a cross-over hotspot in the C4-H-2D region.

HSPA1A HSPA1B HSPA1L

1.79e-06615738199408
Pubmed

BAG-1 modulates the chaperone activity of Hsp70/Hsc70.

HSPA1A HSPA1B HSPA8

1.79e-06615739305631
Pubmed

RING finger protein RNF207, a novel regulator of cardiac excitation.

HSPA1A HSPA1B HSPA8

1.79e-066157325281747
Pubmed

Three Hsp70 genes are located in the C4-H-2D region: possible candidates for the Orch-1 locus.

HSPA1A HSPA1B HSPA1L

1.79e-06615738449501
InteractionOPALIN interactions

ATR SLC39A3 ERAP1 RNF213 HEATR1 NCAPG2 NUP205 FANCD2 PRKDC HSPA1L HSPA8

6.31e-0720915411int:OPALIN
InteractionRPS6KA1 interactions

DOCK4 MAGI1 RPS6KA4 GOPC RPS6KA5 CAPN1 NCAPG2 PAPOLG HSPA1A KYNU HSPA8

1.49e-0622815411int:RPS6KA1
InteractionSWAP70 interactions

EZR HSP90B1 TRAF3 FARSB HSPA1A HSPA8 DYNC1H1

2.23e-06781547int:SWAP70
InteractionCDC42 interactions

MAGI1 TRAF3 ZNF234 ATR RPS6KA5 ZSWIM5 LRRK2 SRPRA HEATR1 NCAPG2 ADCY9 ITPR1 NUP205 ITPR2 ITPR3 FANCD2 MYOF SBNO1 MCM3AP NCAPD2 DOCK7 PRKDC ADGRL2 HSPA1A KYNU COG4 ERICH6

2.56e-06132315427int:CDC42
InteractionKCNA3 interactions

EZR MAGI1 HSP90B1 CMTR1 TMEM165 LRRK2 FARSB RNF213 SRPRA CHD2 ADCY9 PAPOLG NCAPD2 DOCK7 PRKDC ADGRL2 HSPA1B HSPA8 DYNC1H1 EPB41 SYNCRIP

3.09e-0687115421int:KCNA3
InteractionUHRF2 interactions

ATR CHD2 SKP1 NCAPG2 TASOR2 FANCD2 PRKDC HSPA1L HSPA8 FBXW7

3.29e-0620015410int:UHRF2
InteractionSTYK1 interactions

GOPC TMEM165 SRPRA HEATR1 NUP205 FANCD2 PRKDC ADGRL2 HSPA1B

4.17e-061611549int:STYK1
InteractionC19orf38 interactions

SLC39A3 RPS6KA5 RNF213 NCAPG2 RRP1 FANCD2 PRKDC

4.30e-06861547int:C19orf38
InteractionMETTL21A interactions

HSPA1A HSPA1B HSPA1L HSPA8 DYNC1H1

7.60e-06361545int:METTL21A
InteractionPML interactions

EZR HSP90B1 CMTR1 GOPC ATR RNF213 SRPRA ZNF318 HEATR1 SKP1 NUP205 ITPR2 PAPOLG FANCD2 SBNO1 DLAT PARP9 HSPA1A HSPA8 SYNCRIP FBXW7

8.90e-0693315421int:PML
InteractionELP1 interactions

EZR ELP6 FANCD2 PASK PRKDC HSPA1A FKBP5 DYNC1H1 FBXW7

1.13e-051821549int:ELP1
InteractionHLA-B interactions

EZR ATR SLC39A3 ERAP1 RNF213 HEATR1 NUP205 FANCD2 PRKDC HSPA8

1.57e-0523915410int:HLA-B
InteractionSIRT7 interactions

ATR CAPN1 CHD2 ZNF318 HEATR1 RRP1 TASOR2 NUP205 ITPR3 MCM3AP NCAPD2 DOCK7 DLAT ATIC PRKDC MTREX DYNC1H1 SYNCRIP

1.59e-0574415418int:SIRT7
InteractionMAPK4 interactions

RPS6KA4 RPS6KA5 PRKDC MAPK4 HSPA8 FKBP5

1.72e-05711546int:MAPK4
InteractionCA14 interactions

ATR SLC39A3 HEATR1 RRP1 FANCD2 COG4

1.72e-05711546int:CA14
InteractionNUP155 interactions

EVC2 GOPC SRPRA ADCY9 ITPR1 NUP205 ITPR2 ITPR3 FANCD2 TNFSF13B MCM3AP DOCK7 HSPA1A COG4

1.84e-0547715414int:NUP155
InteractionFBXO43 interactions

EZR SKP1 ATIC HSPA1L HSPA8 DYNC1H1

2.18e-05741546int:FBXO43
InteractionZNF112 interactions

ZNF112 ZNF235 ZNF284

2.38e-0581543int:ZNF112
InteractionTRIM38 interactions

HSPA1A HSPA1B HSPA1L HSPA8 FBXW7

2.89e-05471545int:TRIM38
InteractionCCNI2 interactions

HSPA1B HSPA1L HSPA8

3.55e-0591543int:CCNI2
InteractionRASEF interactions

ITPR1 ITPR2 ITPR3 DYNC1H1

3.66e-05251544int:RASEF
InteractionHSPBP1 interactions

EVC2 TBC1D32 ULK4 MAPK4 HSPA1A HSPA1B HSPA1L HSPA8

4.21e-051661548int:HSPBP1
InteractionCCDC117 interactions

HSPA1A HSPA1B HSPA1L HSPA8

4.30e-05261544int:CCDC117
InteractionGPR182 interactions

ATR ERAP1 TMEM165 RNF213 SRPRA HEATR1 NCAPG2 NUP205 FANCD2 NCAPD2 PRKDC MICU2 COG4

4.87e-0545515413int:GPR182
InteractionCCDC142 interactions

HSPA1B HSPA1L HSPA8

5.05e-05101543int:CCDC142
InteractionMAP2K2 interactions

HSP90B1 ATR NCAPG2 PASK MCM3AP DOCK7 HSPA1A HSPA1B HSPA8 FKBP5

5.69e-0527815410int:MAP2K2
InteractionPOLD1 interactions

HSP90B1 ATR CAPN1 SKP1 ITPR1 NUP205 PRKDC HSPA8 FKBP5 WDR44 FBXW7

5.82e-0533715411int:POLD1
InteractionFANCC interactions

HSP90B1 CAPN1 FANCD2 HSPA1A HSPA8 FBXW7

6.22e-05891546int:FANCC
InteractionBAG5 interactions

LRRK2 RNF213 ZNF318 FANCD2 TBC1D32 DOCK7 ULK4 HSPA1A HSPA1L KYNU HSPA8

6.47e-0534115411int:BAG5
InteractionFBXL15 interactions

SKP1 HECW2 HSPA1B HSPA8

6.71e-05291544int:FBXL15
InteractionFKBP8 interactions

EVC2 SRPRA ADCY9 ITPR1 ITPR2 ITPR3 FANCD2 TBC1D32 ULK4 PRKDC MAPK4 HSPA1L FKBP5 FBXW7

6.80e-0553815414int:FKBP8
InteractionSPN interactions

EZR ATR HEATR1 NCAPG2 FANCD2

7.42e-05571545int:SPN
InteractionDHFR2 interactions

HSP90B1 ASIC1 SRPRA ADCY9 ITPR2 ITPR3 PASK HSPA1B HSPA1L HSPA8

7.86e-0528915410int:DHFR2
InteractionILVBL interactions

HEATR1 NCAPG2 NUP205 FANCD2 TBC1D32 MAPK4 COG4 HSPA8

8.38e-051831548int:ILVBL
InteractionARHGAP24 interactions

EZR HSP90B1 ZNF781 FARSB ZNF235 NCAPG2 DLAT ATIC MTREX HSPA1A HSPA1B HSPA8 SYNCRIP

9.47e-0548615413int:ARHGAP24
InteractionGPR45 interactions

ATR SLC39A3 ERAP1 RNF213 HEATR1 NCAPG2 NUP205 FANCD2 MCM3AP COG4

1.07e-0430015410int:GPR45
InteractionELP4 interactions

ELP6 FAM98B HSPA1A HSPA1L HSPA8

1.11e-04621545int:ELP4
InteractionISG15 interactions

EZR SPAST RNF213 ZNF318 NUP205 FANCD2 MYOF ATIC PRKDC HSPA1A HSPA1B HSPA8 DYNC1H1

1.11e-0449415413int:ISG15
InteractionLRRC28 interactions

HSPA1B HSPA1L HSPA8

1.18e-04131543int:LRRC28
InteractionNCAPG2 interactions

FAXC NCAPG2 FANCD2 TNFSF13B NCAPD2 FKBP5

1.19e-041001546int:NCAPG2
InteractionCD274 interactions

EZR HSP90B1 ATR CAPN1 FARSB SRPRA HEATR1 DOCK7 PRKDC COG4 SYNCRIP

1.30e-0436915411int:CD274
InteractionPSMB3 interactions

LRRK2 ELP6 HEATR1 SKP1 FANCD2 HECW2 HSPA1A DYNC1H1

1.45e-041981548int:PSMB3
InteractionIRAG1 interactions

ITPR1 ITPR2 ITPR3

1.50e-04141543int:IRAG1
InteractionZNF284 interactions

ZNF223 ZNF112 ZNF284

1.50e-04141543int:ZNF284
InteractionDNAJB6 interactions

GOPC LRRK2 HEATR1 FANCD2 SKAP2 HSPA1A HSPA1B HSPA1L HSPA8 FKBP5 FBXW7

1.64e-0437915411int:DNAJB6
InteractionRPL13AP17 interactions

GOPC SYNCRIP

1.73e-0431542int:RPL13AP17
InteractionHSPH1 interactions

EZR GOPC LRRK2 FARSB FANCD2 HECW2 HSPA1A HSPA1B HSPA1L HSPA8 DYNC1H1 WDR44

1.75e-0444815412int:HSPH1
InteractionCD40 interactions

TRAF3 ATR RNF213 HEATR1 FANCD2 COG4 HSPA8

1.77e-041531547int:CD40
InteractionDCLRE1B interactions

FANCD2 PRKDC HSPA1A HSPA8

1.78e-04371544int:DCLRE1B
InteractionCABP1 interactions

CACNA1A ITPR1 ITPR3

1.86e-04151543int:CABP1
InteractionCYP2W1 interactions

HSPA1B HSPA1L HSPA8

1.86e-04151543int:CYP2W1
InteractionMCM2 interactions

EZR HSP90B1 ATR CAPN1 FARSB RNF213 ZNF318 HEATR1 FAM98B SKP1 FANCD2 SBNO1 PRKDC HSPA1A HSPA1L HSPA8 FKBP5 DYNC1H1 SYNCRIP FBXW7

2.22e-04108115420int:MCM2
InteractionVSIG1 interactions

ATR TMEM165 HEATR1 RRP1 COG4

2.26e-04721545int:VSIG1
InteractionPINK1 interactions

EZR HSP90B1 TRAF3 ATR FARSB DLAT ATIC PRKDC HSPA1A HSPA1B HSPA1L HSPA8 FKBP5 DYNC1H1 SYNCRIP

2.27e-0467915415int:PINK1
InteractionTESPA1 interactions

ITPR1 ITPR2 ITPR3

2.28e-04161543int:TESPA1
InteractionBRAF interactions

HSP90B1 FANCD2 MYOF DOCK7 HSPA1A HSPA8 FKBP5 FBXW7

2.31e-042121548int:BRAF
InteractionGGCT interactions

FANCD2 HECW2 HSPA1A HSPA8 FBXW7

2.41e-04731545int:GGCT
InteractionCDK3 interactions

SHLD2 SKP1 RIN2 HSPA1L HSPA8 FKBP5

2.44e-041141546int:CDK3
InteractionDNAJB5 interactions

CACNA1A ITPR3 HSPA1A HSPA1L HSPA8 FKBP5

2.44e-041141546int:DNAJB5
InteractionPLRG1 interactions

ARHGAP36 FANCD2 PRKDC MTREX HSPA1A HSPA8 DYNC1H1 SYNCRIP

2.62e-042161548int:PLRG1
InteractionAKT1 interactions

HSP90B1 RPS6KA4 RPS6KA5 CAPN1 LRRK2 ITPR1 ITPR3 FANCD2 PRKDC MAPK4 HSPA1A HSPA8 FKBP5 FBXW7

2.82e-0461715414int:AKT1
InteractionPPP6R1 interactions

EZR SRPRA SKP1 FANCD2 PRKDC HSPA1A HSPA8

2.92e-041661547int:PPP6R1
InteractionVCAM1 interactions

EZR CAPN1 FARSB HEATR1 NUP205 FANCD2 PRKDC HSPA1A HSPA1B HSPA8 DYNC1H1 SYNCRIP

2.98e-0447515412int:VCAM1
InteractionTNFSF13B interactions

HEATR1 NCAPG2 FANCD2 TNFSF13B NCAPD2 PRKDC

3.08e-041191546int:TNFSF13B
InteractionCOPS6 interactions

SHLD2 HSP90B1 SKP1 ABCC6 DOCK7 HSPA1A HSPA1B HSPA1L HSPA8 SYNCRIP FBXW7

3.09e-0440815411int:COPS6
InteractionMGARP interactions

ATR RNF213 HEATR1 NCAPG2 FANCD2 MCM3AP PRKDC MICU2

3.15e-042221548int:MGARP
InteractionDCLRE1C interactions

ATR PASK PRKDC FBXW7

3.21e-04431544int:DCLRE1C
InteractionFAM174A interactions

RPS6KA4 GOPC ATR RPS6KA5 RNF213 HEATR1 NCAPG2 FANCD2

3.34e-042241548int:FAM174A
InteractionGPR17 interactions

ATR ERAP1 RNF213 HEATR1 ITPR2 FANCD2 NCAPD2 PRKDC COG4

3.36e-042831549int:GPR17
InteractionIGLV3-21 interactions

FANCD2 HSPA8

3.45e-0441542int:IGLV3-21
InteractionHEMGN interactions

TRAF3 HSPA1A HSPA8 FBXW7

3.51e-04441544int:HEMGN
InteractionGSK3B interactions

HSP90B1 ERAP1 CAPN1 LRRK2 FARSB SKP1 NUP205 PASK MYOF HECW2 DOCK7 ATIC PRKDC HSPA1A HSPA8 FKBP5 FBXW7

3.54e-0486815417int:GSK3B
InteractionCLUAP1 interactions

TMEM165 SRPRA NCAPG2 FSIP2 CADPS2 HSPA1A HSPA8 FKBP5

3.55e-042261548int:CLUAP1
InteractionTMPRSS11B interactions

GOPC SLC39A3 ASIC1 TMEM165 SRPRA ITPR1 ITPR3 FANCD2 DLAT PRKDC ADGRL2

3.64e-0441615411int:TMPRSS11B
InteractionDNAJB8 interactions

LRRK2 HSPA1A HSPA1L HSPA8 FKBP5

3.70e-04801545int:DNAJB8
InteractionCIAO2A interactions

RPS6KA4 GOPC RPS6KA5 KCNIP1 PAPOLG MCM3AP DOCK7

3.75e-041731547int:CIAO2A
InteractionDYRK2 interactions

LRRK2 PRKDC MAPK4 HSPA1A HSPA1B HSPA8 FBXW7

3.75e-041731547int:DYRK2
InteractionMETTL21C interactions

HSPA1L HSPA8 DYNC1H1

3.88e-04191543int:METTL21C
InteractionEPB42 interactions

FANCD2 HSPA8 EPB41

3.88e-04191543int:EPB42
InteractionSNCA interactions

EZR SPAST LRRK2 SRPRA HEATR1 SKP1 SLC6A2 SLC6A3 DOCK7 MTREX HSPA1A HSPA1L HSPA8 DYNC1H1 FBXW7

3.98e-0471615415int:SNCA
InteractionDNAJC16 interactions

HSP90B1 SRPRA ADCY9 ITPR1 ITPR2 ADGRL2 HSPA1A HSPA8

4.34e-042331548int:DNAJC16
InteractionDNAJC5B interactions

ADCY9 NCAPD2 ADGRL2 HSPA1A HSPA1L

4.39e-04831545int:DNAJC5B
InteractionFLT1 interactions

ATR RNF213 SRPRA NUP205 PRKDC HSPA1B DYNC1H1

4.60e-041791547int:FLT1
InteractionP2RY8 interactions

SLC39A3 ERAP1 HEATR1 NCAPG2 NUP205 FANCD2 COG4

4.60e-041791547int:P2RY8
InteractionLPCAT1 interactions

FANCD2 DOCK7 MAPK4 HSPA1A HSPA8 FBXW7

4.74e-041291546int:LPCAT1
Cytoband19q13.2

ZNF223 ZNF224 ZNF226 ZNF112 ZNF235 TMEM145 ZNF222

1.70e-06164157719q13.2
CytobandEnsembl 112 genes in cytogenetic band chr19q13

ZNF234 ZNF155 ZNF781 ZNF223 ZNF224 ZNF226 ZNF112 ZNF230 ZNF235 ZNF284 TMEM145 CD37 ZNF222 NLRP13

6.57e-05119215714chr19q13
Cytoband19q13.31

ZNF234 ZNF230 ZNF284

1.34e-0429157319q13.31
GeneFamilyInositol 1,4,5-triphosphate receptors|Protein phosphatase 1 regulatory subunits

ITPR1 ITPR2 ITPR3

2.19e-0731103297
GeneFamilyHeat shock 70kDa proteins

HSPA1A HSPA1B HSPA1L HSPA8

2.90e-06171104583
GeneFamilyRNA polymerase subunits

POLR2J3 POLR2J POLR2J2

7.14e-04291103726
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF234 ZNF155 ZNF781 ZNF318 ZNF223 ZNF224 ZNF226 ZNF112 ZNF230 ZNF235 ZNF284 ZNF222

1.40e-037181101228
GeneFamilyMitogen-activated protein kinase-activated protein kinases

RPS6KA4 RPS6KA5

1.95e-031111021156
GeneFamilyPDZ domain containing

MAGI1 INTU GOPC TIAM2 CARD14

2.37e-0315211051220
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

EZR FRMD4B EPB41

3.49e-035011031293
CoexpressionDEN_INTERACT_WITH_LCA5

HSPA1A HSPA1B HSPA1L HSPA8

1.59e-05261554M1380
CoexpressionKRISHNAN_FURIN_TARGETS_UP

HSPA1A HSPA1B HSPA8

2.36e-05101553MM1243
CoexpressionHOWARD_NEUTROPHIL_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_1DY_UP

DOCK4 CACNA1A CMTR1 ATR RNF213 FRMD4B NUP205 GVINP1 TNFSF13B TLR5 PARP9

2.41e-0539415511M40996
CoexpressionGSE10273_HIGH_VS_LOW_IL7_TREATED_IRF4_8_NULL_PRE_BCELL_DN

TRAF3 RPS6KA4 GBP7 ITPR2 ITPR3 PAPOLG TMEM129 DYNC1H1

2.54e-051991558M316
CoexpressionGSE19888_ADENOSINE_A3R_INH_VS_ACT_IN_MAST_CELL_DN

INTU SLC39A3 GBP7 TRO RNF213 ITPR1 MMRN1 TNFSF13B

2.54e-051991558M7341
CoexpressionGSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_WITH_IL2_TREATMENT_UP

GBP7 TNC FARSB NCAPG2 FANCD2 NCAPD2 FKBP5 RAD54L

2.64e-052001558M9281
CoexpressionGSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_DN

ZNF234 TMEM165 ZNF112 RIN2 DLAT PARP9 SDS ZNF222

2.64e-052001558M3127
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000

DOCK4 MAGI1 RPS6KA5 MATN2 RNF213 CPA1 KCNIP1 FRMD4B ITPR1 ITPR2 MYOF RIN2 PLXNA4 ADGRL2 HSPA8 FKBP5 NENF

3.08e-0578314717gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000

ASZ1 ATR RNF213 ZNF318 HEATR1 STK31 TASOR2 NUP205 FANCD2 TBC1D32 PASK SBNO1 MOV10L1 PRKDC MTREX RAD54L FBXW7

4.71e-0581014717gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

ASZ1 ATR RPS6KA5 ZSWIM5 ZNF318 HEATR1 ZNF235 STK31 NCAPG2 TASOR2 PAPOLG FANCD2 MOV10L1 PRKDC RAD54L WDR44 FBXW7

5.48e-0582014717gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#3_top-relative-expression-ranked_1000

DOCK4 MAGI1 MATN2 RNF213 ITPR1 RIN2 PLXNA4 NENF

5.68e-051911478gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k3_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000

DOCK4 MAGI1 TNC MATN2 RNF213 CPA1 NCAPG2 FRMD4B MYOF RIN2 NCAPD2 ST8SIA2 PLXNA4 ADGRL2 HSPA8 FKBP5 RAD54L

6.08e-0582714717gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_500

ASZ1 ATR ZNF318 STK31 NCAPG2 TASOR2 FANCD2 MOV10L1 PRKDC RAD54L WDR44

7.90e-0538514711gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_500
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#2_top-relative-expression-ranked_1000

ASZ1 ZNF318 STK31 SBNO1 MOV10L1

8.78e-05651475gudmap_developingGonad_e12.5_epididymis_k2_1000
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_k-means-cluster#4_top-relative-expression-ranked_1000

ATR ZNF318 STK31 TASOR2 MOV10L1 PRKDC

1.18e-041101476gudmap_dev gonad_e13.5_M_GermCell_Oct_k4_1000
CoexpressionAtlasMyeloid Cells, DC.103-11b+F4/80lo.Kd, CD45+ CD11c+ I-A/I-E+ CD11b+ F4/80lo, Kidney, avg-3

DOCK4 LRRK2 ANKH FRMD4B MYOF RIN2 DOCK7 SKAP2 HSPA1A HSPA1B KYNU

1.26e-0440614711GSM854273_500
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#3_top-relative-expression-ranked_500

ZNF318 STK31 MOV10L1 PRKDC

1.36e-04381474gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k3_500
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#2_top-relative-expression-ranked_1000

ATR STK31 TASOR2 MOV10L1 PRKDC WDR44

1.50e-041151476gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k2_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500

DOCK4 MATN2 RNF213 CPA1 FRMD4B MYOF NCAPD2 ST8SIA2 PLXNA4 ADGRL2 FKBP5

1.63e-0441814711gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_1000

MATN2 RNF213 CPA1 FRMD4B ADGRL2 HSPA8

1.73e-041181476gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_1000
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000

ASZ1 ATR RPS6KA5 FARSB RNF213 HEATR1 STK31 NCAPG2 TASOR2 NUP205 FANCD2 PASK MOV10L1 PRKDC RAD54L WDR44

1.89e-0482214716gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
CoexpressionAtlasdev gonad_e13.5_F_DevVascOvary_Flk_k-means-cluster#2_top-relative-expression-ranked_1000

DOCK4 MAGI1 ITPR2 ADGRL2

2.01e-04421474gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_k2_1000
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_1000

DOCK4 MAGI1 RPS6KA5 MATN2 FAXC RNF213 CPA1 NCAPG2 FRMD4B NCAPD2 ST8SIA2 PLXNA4 ADGRL2 HSPA1A HSPA1L HSPA8

2.14e-0483114716gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_200

DOCK4 MATN2 RNF213 PLXNA4

2.41e-04441474gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_200
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000

TNC MATN2 RNF213 CPA1 NCAPG2 FRMD4B FANCD2 MYOF NCAPD2 ST8SIA2 DOCK7 ADGRL2 HSPA8 FKBP5 PGBD5

2.92e-0476814715gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_1000

ZNF318 STK31 MOV10L1 PRKDC FBXW7

3.12e-04851475gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k1_1000
CoexpressionAtlasMyeloid Cells, DC.103-11b+.SI, CD45+ MHCII+ CD11c-hi CD11b+ CD103- F4/80+, Small Intestine, avg-7

DOCK4 GBP7 FRMD4B MYOF TNFSF13B RIN2 DOCK7 HSPA1A HSPA1B KYNU

3.31e-0438114710GSM854262_500
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000

DOCK4 ASZ1 ATR GBP7 ZSWIM5 RNF213 CHD2 ZNF318 LHX8 STK31 FRMD4B ITPR2 SBNO1 MOV10L1 WDR44

3.35e-0477814715gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#4_top-relative-expression-ranked_200

ASZ1 STK31 MOV10L1

3.40e-04201473gudmap_developingGonad_e16.5_ovary_200_k4
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#1_top-relative-expression-ranked_500

DOCK4 MAGI1 RNF213 RIN2 PLXNA4

4.28e-04911475gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k1_500
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

EZR MAGI1 LRRK2 CHD2 FRMD4B ADCY9 PIP5K1B CADPS2

4.56e-07194157897534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF112 STK31 FAM135B SLC6A3 MOV10L1 TLR5 SDS

8.11e-071441577e9d62f202f0fa8747961036ef0eafed91fe8a42f
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HTR4 TNC MATN2 KCNIP1 TIAM2 SLC9C1 PLXNA4

3.46e-06179157702c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EZR TRAF3 KCNH8 LRRK2 RAP1GAP2 RNF213 ITPR3

4.95e-061891577aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EZR TRAF3 KCNH8 LRRK2 RAP1GAP2 RNF213 ITPR3

4.95e-0618915778977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCellControl-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

DOCK4 HECW2 RIN2 PIP5K1B CADPS2 ADGRL2 FKBP5

5.12e-0619015777f3f419fffe02934b6f27b697f7a6401072491ed
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EZR MAGI1 LRRK2 RAP1GAP2 RNF213 ITPR3 MYOF

5.87e-061941577e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

HTR4 TNC MATN2 KCNIP1 TIAM2 MYOF PLXNA4

6.93e-0619915776b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCellCOVID-19-lung|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK4 RNF213 PARP9 SKAP2 HSPA1A HSPA1B KYNU

6.93e-061991577155b03b859157013e9142e9248551369127d9204
ToppCellsevere_influenza-Classical_Monocyte|World / disease group, cell group and cell class (v2)

LRRK2 MYOF TNFSF13B TLR5 SKAP2 HSPA1A FKBP5

6.93e-061991577b8adbd6ff5e5602259118a69fd7c77e8348a27e4
ToppCellsevere_influenza|World / disease group, cell group and cell class (v2)

LRRK2 MYOF TNFSF13B TLR5 SKAP2 HSPA1A FKBP5

7.16e-0620015772c965ec0c33a797c227a06dac90b5ecb959816f6
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

HTR4 TNC MATN2 ITPR1 MYOF SLC9C1 PLXNA4

7.16e-06200157787827041663013f5e7273168dc8709d69840e7ce
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

C15orf62 EVC2 POLR2J3 RNF213 CHD2 CFAP57

8.50e-061351576ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Papillary_Muscle_Invasive_Urothelial_Carcinoma-8|TCGA-Bladder / Sample_Type by Project: Shred V9

ZNF234 ZNF155 ZNF223 HID1 ZNF226 ZNF222

1.49e-05149157689705865e94360c1288ee98c5a6b381f3c6242b3
ToppCelldroplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSWIM5 FRMD4B SLC6A2 MRPL39 HSPA1A

2.07e-05941575d25f096626af873f724a8cd6454ed56e33fd9854
ToppCelldroplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSWIM5 FRMD4B SLC6A2 MRPL39 HSPA1A

2.07e-059415752fb80a08f823295fa4c3e6494bf020e5b4052f0f
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C15orf62 CACNA1S PSD2 P2RX2 CD37 KYNU

2.16e-051591576656aa20706bdba81bbcc3e68e6058215b92b8802
ToppCellMild_COVID-19-Myeloid-MoAM2|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

DOCK4 CACNA1A RIN2 HSPA1A HSPA1B SDS

2.40e-051621576e5fc80ab19d513af6a7e677a5e67bfebca2e963b
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A ATP10B POLR2J2 MMP8 PGBD5 ZNF222

2.57e-051641576d6f71d804bb65301c02ea4e6673e20688b5fcd5b
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C15orf62 ARHGAP36 TRO FAXC LHX8 PLXNA4

2.75e-051661576548d0d6c0ffd564036ddba78620734220ebb73d7
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C15orf62 ARHGAP36 TRO FAXC LHX8 PLXNA4

2.75e-05166157680e164a89d22098cabe4a99a78283ba69ea0561e
ToppCell3'_v3-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue

DOCK4 ANKH FRMD4B ITPR2 TLR5 HSPA1A

3.04e-051691576241644823e6f949aaf4c671d4579721d7ef6b0e5
ToppCellfacs-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK4 ERAP1 SLC6A2 HECW2 FKBP5 CARD14

3.14e-0517015768e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCellfacs-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK4 ERAP1 SLC6A2 HECW2 FKBP5 CARD14

3.14e-05170157667d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCellmetastatic_Lymph_Node-Endothelial_cells-Lymphatic_ECs|metastatic_Lymph_Node / Location, Cell class and cell subclass

MAGI1 MATN2 KCNIP1 MMRN1 MOV10L1 ST8SIA2

3.58e-051741576d551bc29afef071adf4c9bb80345352ec33441d8
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FRMD4B PASK MYOF HSPA1A HSPA1B FKBP5

3.69e-0517515766374ab186d7ccf7f6dfb858267edba8962789e15
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

HSP90B1 CMTR1 RNF213 HEATR1 ZNF224 ZNF235

3.81e-0517615763de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellSevere-CD4+_T_activated|Severe / Disease group and Cell class

RNF213 FRMD4B TNFSF13B HSPA1A HSPA1B HSPA8

3.93e-051771576a08f170f1143fcdd7d0842a54d9b807a4548f8b7
ToppCellSevere-CD4+_T_activated|World / Disease group and Cell class

RNF213 FRMD4B TNFSF13B HSPA1A HSPA1B HSPA8

4.06e-051781576ef6111238703579a34bd6948bd9d4ca6b7e16063
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP47 CACNA1S ST8SIA2 ULK4 ERICH6 DNAH11

4.06e-051781576b1db59344c074c7c80169fc2c5cd5fc89f3fe463
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP47 CACNA1S ST8SIA2 ULK4 ERICH6 DNAH11

4.06e-051781576579cdc14f28b459e200ae2102e0bd4df8a2c0dcb
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175|Adult / Lineage, Cell type, age group and donor

HECW2 RIN2 PLCXD3 ADGRL2 HSPA1A HSPA1B

4.60e-0518215768b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCellNS-moderate-d_07-13-Myeloid-Monocyte-derived_Macrophage|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GBP7 RNF213 ITPR2 TNFSF13B RIN2 FKBP5

4.60e-051821576e03e995e5fd14fc6a7559b83c0ca4e7ccc8e3d0f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

MAGI1 ZSWIM5 LRRK2 SLC9C1 PIP5K1B CADPS2

4.74e-0518315766847c1252d6bb105524f812658112517fd351eab
ToppCellLPS-IL1RA|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK4 TRAF3 EVC2 GBP7 SLC9C1 HECW2

4.88e-051841576c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNH8 LRRK2 KCNIP1 ITPR2 PLCXD3 MMP3

4.88e-051841576658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S HSP90B1 EVC2 FAXC SRPRA HID1

4.88e-0518415761da7936a2616986efd5de601ad525f1f2355128a
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK4 LRRK2 RNF213 CHD2 TNFSF13B PARP9

5.03e-051851576f30fb9d75cdb757b206312992aaf7485bc900f96
ToppCellcritical-Myeloid-Monocyte-derived_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CMTR1 RNF213 MYOF TNFSF13B RIN2 HSPA1B

5.34e-05187157672e4aec49ea0c5fe6cee2a1a46369dbc90cd3fad
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

POLR2J3 RNF213 CHD2 TASOR2 ITPR1 DYNC1H1

5.50e-051881576ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellCOPD-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

HECW2 RIN2 PIP5K1B ADGRL2 HSPA1B FKBP5

5.50e-0518815761aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCellCOVID-19-lung-Vein_EC|lung / Disease (COVID-19 only), tissue and cell type

MAGI1 MMRN1 HECW2 PLCXD3 CADPS2 ADGRL2

5.50e-051881576d582b76fc2faac526c9bf97503041129e1a6a211
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Adult / Lineage, Cell type, age group and donor

HECW2 RIN2 PLCXD3 ADGRL2 HSPA1A HSPA1B

5.50e-051881576e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

FRMD4B ITPR1 ITPR2 MMRN1 RIN2 CADPS2

5.67e-051891576c81787a8c662db5d7814c583dd64562857629e81
ToppCellCOVID-19-lung-Vein_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

MMRN1 HECW2 PLCXD3 CADPS2 ADGRL2 HSPA1A

5.83e-0519015761caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK4 HECW2 RIN2 PLCXD3 CADPS2 ADGRL2

5.83e-0519015760e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK4 EZR MAGI1 KCNIP1 PIP5K1B MAPK4

5.83e-05190157630b50d183d7649146eb1e79b47ba897355f1998a
ToppCellCOVID-19-Heart-EC_(POSTN)|Heart / Disease (COVID-19 only), tissue and cell type

MATN2 FRMD4B ITPR2 MMRN1 MOV10L1 PLXNA4

6.18e-051921576c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAGI1 LRRK2 DESI2 ABCC6 ITPR3 PIP5K1B

6.18e-05192157629f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KCNIP1 NCAPG2 FANCD2 PASK PLXNA4 RAD54L

6.36e-051931576bbdfda6665941cfa1965418bb91ef9ff43b1326f
ToppCellmoderate-Myeloid-Monocyte-derived_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CACNA1A RNF213 MYOF RIN2 HSPA1A HSPA1B

6.36e-05193157622455801194bd8c73c5c397f5eac4f723429c383
ToppCellCOPD-Myeloid-Macrophage|World / Disease state, Lineage and Cell class

DOCK4 LRRK2 PAPOLG KYNU FKBP5 SDS

6.55e-0519415767d682408e9a6239a4e47befc9376e760cc3d133a
ToppCellMild/Remission-B_activate-7|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

CACNA1A POLR2J3 RNF213 TNFSF13B CD37 PARP9

6.55e-05194157601c97543972159a9468272da06e7e611e2c21fae
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRAF3 ABCC6 ITPR1 CD37 PIP5K1B SKAP2

6.55e-051941576cbc4b6422777117e4123804168c23f19d1b79486
ToppCellIPF-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

GVINP1 HECW2 RIN2 PIP5K1B ADGRL2 FKBP5

6.55e-051941576777ce41c3f22c591e2d81120f189b834e53ffb4b
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP47 INTU SHOC1 ULK4 CFAP57 DNAH11

6.55e-0519415764a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 SLC44A2 HECW2 RIN2 ADGRL2 HSPA1A

6.74e-05195157623ced69fd904f1d4114b1a7f99f4b5f65ea8824b
ToppCellsevere-Lymphocytic-B_cells_1|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

EZR KCNH8 ZNF318 ITPR1 CD37 KYNU

6.74e-05195157673e39005a597e13aea571ae6ae5824d1c7448b71
ToppCellCOVID-19_Mild-PLT_5|COVID-19_Mild / Disease Group and Platelet Clusters

EZR HSP90B1 RNF213 NCAPD2 HSPA8 FKBP5

6.74e-051951576bdf9a6ea1bd83c72a834c45f86ce3f4643a9bef3
ToppCellB_cells-ISG-high_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

CACNA1A CMTR1 RNF213 TNFSF13B RIN2 PARP9

6.74e-051951576b64d9e1a8834401b4dc501566546647754ae21fc
ToppCellCOVID-19-Heart-EC_1|Heart / Disease (COVID-19 only), tissue and cell type

DOCK4 MAGI1 SLC9C1 HECW2 RIN2 CADPS2

6.74e-05195157650a193475db1bb1e05b8590225a553688c372c14
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1A KCNH8 LRRK2 PLXNA4 CADPS2 FBXW7

6.74e-051951576787e95fb59c40bba784544b662fac37606ae1427
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK4 MAGI1 ADCY9 PIP5K1B CADPS2 FBXW7

6.93e-051961576ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellIPF-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

HECW2 PIP5K1B ADGRL2 HSPA1A HSPA1B FKBP5

6.93e-0519615768f0f72ead06abe02b575e443552eacc2151077ef
ToppCellCOVID-19-lung-Capillary_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK4 MAGI1 HECW2 CADPS2 ADGRL2 HSPA1A

6.93e-051961576ac28e9be288af6f00a841aea4ce4b99aed6b4505
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK4 RNF213 FRMD4B ITPR2 KYNU SDS

7.13e-05197157610190b877bf46ba2163d203df9dd3b498c66e52f
ToppCell10x5'v1-week_12-13-Myeloid_macrophage-stroma-stromal_macrophage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

DOCK4 ANKH FRMD4B ITPR2 SDS PGBD5

7.13e-051971576075044c17f1c52008cd3c292c15cbf485b50411e
ToppCellCaecum-(6)_Macrophage-(61)_LYVE1_Macrophage|Caecum / shred on region, Cell_type, and subtype

DOCK4 LRRK2 MYOF RIN2 TLR5 KYNU

7.33e-051981576e684c3934c163aef4d284b69435832d2c9614f2a
ToppCellCaecum-Macrophage-LYVE1_Macrophage|Caecum / Region, Cell class and subclass

DOCK4 LRRK2 MYOF RIN2 TLR5 KYNU

7.33e-051981576a92c0cacb775aca6bbb302bd9e22c081a112a44d
ToppCellCaecum-T_cell-Th1|T_cell / Region, Cell class and subclass

FRMD4B MMRN1 HSPA1A HSPA1B HSPA1L HSPA8

7.53e-05199157613a80e6d3cf9c831edbe0644545071153e35f82b
ToppCellcontrol-HLA-DR+_CD83+_Monocyte|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MYOF TNFSF13B RIN2 HSPA1A PGBD5 FBXW7

7.53e-051991576f1b370d2869ad29c9d8ff41fdcc486fffa781ee2
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Stem_cells|GW08 / Sample Type, Dataset, Time_group, and Cell type.

FAM98B NCAPG2 RRP1 PASK FKBP5 RAD54L

7.75e-052001576691b3edf7d8449556e8bf611662eb85772959f0f
ToppCellCOVID-19|World / group, cell type (main and fine annotations)

HSP90B1 SKAP2 HSPA1A HSPA1B KYNU HSPA8

7.75e-052001576ac38a468559c33ee00152735ce6e408f3f48df84
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

DOCK4 ANKH FRMD4B HSPA1A SDS NENF

7.75e-052001576195862a319794e57f0506757ae45ab70200bc5b4
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid-Megakaryocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF234 RPS6KA5 ANKH ITPR1 HSPA1A HSPA1B

7.75e-0520015760d76b006d8e8b32174e65e400acd0674354b962c
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Stem_cells-Stem_cells|GW08 / Sample Type, Dataset, Time_group, and Cell type.

FAM98B NCAPG2 RRP1 PASK FKBP5 RAD54L

7.75e-05200157636a110aa91a791fdf1142e7869e8aa0d342402d0
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Stem_cells-Neuroepithelial_cell|GW08 / Sample Type, Dataset, Time_group, and Cell type.

FAM98B NCAPG2 RRP1 PASK FKBP5 RAD54L

7.75e-0520015764e077aa7faddcebdfc54667f8b3990704441005b
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Myeloid|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF234 RPS6KA5 ANKH ITPR1 HSPA1A HSPA1B

7.75e-052001576cc8368665bc6bb7c4f39632ccff07ceaa98a7b65
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Stem_cells|GW08 / Sample Type, Dataset, Time_group, and Cell type.

FAM98B NCAPG2 RRP1 PASK FKBP5 RAD54L

7.75e-052001576d17ba4239e1fd702a3d757687110f0f2c6f91ef7
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Meis2-Meis2_Adamts19|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

C15orf62 ASZ1 SLC6A3 DNAH11

1.03e-04691574130b1a56afe6aee01cde56cb983cbc2c41861bb4
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Meis2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

C15orf62 ASZ1 SLC6A3 DNAH11

1.03e-046915746568fcefcc0dca211f2acf6e4066f795489e758d
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSD2 PCDHAC1 ABCC6 FAM135B SLC6A2

1.25e-0413715754dcb15de821439011df1bb0bbd7682d674bd725d
ToppCellfacs-Marrow-B-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSD2 PCDHAC1 ABCC6 FAM135B SLC6A2

1.25e-041371575c05ceeb7b483324604cb3f647d2da2b3786071b1
ToppCellGoblet-gob-2|World / Class top

C5orf22 ATP10B NCAPD2 CADPS2 HSPA1L

1.48e-0414215759b058dc313d1f0edcd8473e342852632e17536a6
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sncg|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EZR TNC KCNIP1 TNFSF13B CADPS2

1.48e-041421575ed91d2ef4c346f7e1a5402846e2a34cee19c24d1
ToppCellPBMC-Mild-cDC_7|Mild / Compartment, Disease Groups and Clusters

C15orf62 CACNA1A ZNF234 ZNF781 ITPR3

1.48e-04142157558f66f35646f281e64d634e6c26adbd1d4e6c830
ToppCellpdx-Tumor_cells-T9|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

EZR ASZ1 PAPOLG SLC6A3 DYNC1H1

1.58e-0414415750b94d978262a826c9254145aa98c6c30240243f9
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

POLR2J3 FAXC RNF213 CHD2 DYNC1H1

1.74e-04147157594998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Six3-Inhibitory_Neuron.Gad1Gad2.Six3-Sst_(Reticular_formation)|Thalamus / BrainAtlas - Mouse McCarroll V32

TIAM2 FSIP2 MMP8 CARD14

1.93e-04811574717751c7a6af08cec7d0e561869e4b292d1f83a5
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Six3-Inhibitory_Neuron.Gad1Gad2.Six3-Sst_(Reticular_formation)-|Thalamus / BrainAtlas - Mouse McCarroll V32

TIAM2 FSIP2 MMP8 CARD14

1.93e-04811574e58f07266b7bad0af9a9856c678b4e0850c9f6c9
ToppCellAdult-Immune-enucleated_erythrocyte-D175|Adult / Lineage, Cell type, age group and donor

KCNH8 HSPA1A HSPA1B HSPA8 ERICH6

2.03e-041521575530d5427d8617dcb223d807b73abee0ef89285f3
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS6KA5 ARHGAP36 CAPN1 FAM135B TLR5

2.36e-041571575370f44047ef438b8f1124c2c2761c150c0d8c57f
ToppCellStriatum-Neuronal-Inhibitory|Striatum / BrainAtlas - Mouse McCarroll V32

PSD2 LHX8 KCNIP1 TMEM145 HSPA8

2.36e-041571575c41ff3fe9de7187575114febfe9bd8733366fb8a
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MATN2 FAXC ZNF112 NCAPG2 DNAH11

2.50e-0415915757ed659163f45e0c4df4782997c0786900c8186c8
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Thalamus / BrainAtlas - Mouse McCarroll V32

KCNH8 HTR4 KCNIP1 ST8SIA2 CADPS2

2.65e-0416115750605134a342d74ae81f33700d6ddfcd6e03aeb7b
ToppCelldroplet-Fat-Scat-21m-Lymphocytic-B_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C15orf62 EZR CACNA1S CD37 DNAH11

2.65e-041611575e52735f955f0a53da5cbe5a2d77a00484e5109b3
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EZR CACNA1S MMRN1 CD37 KYNU

2.65e-0416115757af3b0d4fc7967f6b3e2d255d23fd8b1fd01a7af
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-Zbtb32+_B_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EZR CACNA1S MMRN1 CD37 KYNU

2.65e-04161157598be0cf8228496b31f7f3e0efd8787e95eb626d1
ToppCelldroplet-Limb_Muscle-nan-18m-Myeloid-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNC RAP1GAP2 ABCC6 TLR5 MMP8

2.73e-04162157571d7849108a1b59beff40e46000172c45a2f5439
ToppCell10x5'-Lung-Lymphocytic_T_CD8-Tnaive/CM_CD8|Lung / Manually curated celltypes from each tissue

SHLD2 ASIC1 HID1 PASK HECW2

2.81e-041631575c8e4440d1a857e4da83002303940dd42b273c92e
Drugnoradrealine

CACNA1A CACNA1S EVC2 HTR4 ADCY9 ITPR1 ITPR3 SLC6A2 SLC6A3 P2RX2 PLCXD3 MMP3 MAPK4 MMP8 HSPA8 SDS

2.46e-0657515716CID000000951
DrugMethomyl

HSP90B1 HSPA1A KYNU HSPA8

4.83e-06171574ctd:D008724
Drugbasic copper carbonate

INTU ITPR1 ITPR3

1.76e-0581573CID000025503
DrugNSC7524

CACNA1A CACNA1S ASIC1 ADCY9 ITPR1 ITPR3 SLC6A3 ST8SIA2

3.96e-051821578CID000005657
Drugadenophostin A

ITPR2 ITPR3

4.72e-0521572ctd:C085029
DrugBupropion

SLC6A2 SLC6A3

4.72e-0521572DB01156
DrugIsocaffeine

ITPR1 ITPR3

4.72e-0521572CID000001326
DrugDiethylpropion

SLC6A2 SLC6A3

4.72e-0521572DB00937
DrugPhenmetrazine

SLC6A2 SLC6A3

4.72e-0521572DB00830
Drugadenophostin B

ITPR1 ITPR3

4.72e-0521572CID000656722
DrugRTI-4793-14

SLC6A2 SLC6A3

4.72e-0521572CID000192688
Drugbenzene 1,2,4-trisphosphate

ITPR1 ITPR3

4.72e-0521572CID000192376
DrugAir Pollutants

SPATA7 ZNF234 RPS6KA5 ERAP1 MATN2 SLC44A2 RNF213 HMGCL ZNF224 LHX8 ITPR2 NCAPD2 PARP9 PRKDC SKAP2 HSPA1A FKBP5 EPB41

6.48e-0591715718ctd:D000393
Drugisradipine

CACNA1A CACNA1S ASIC1 ITPR1 ITPR3 SLC6A3

6.83e-051001576CID000003784
DrugFenofibrate [49562-28-9]; Up 200; 11uM; MCF7; HT_HG-U133A

MAGI1 DESI2 ITPR2 ITPR3 PAPOLG P2RX2 TLR5 MMP3

6.93e-0519715787474_UP
DrugMetronidazole [443-48-1]; Up 200; 23.4uM; PC3; HT_HG-U133A

MAGI1 HSP90B1 HTR4 TRO FRMD4B ITPR3 SLC6A2 PASK

7.44e-0519915784023_UP
DrugCNS 1145

CACNA1A CACNA1S ITPR1 ITPR3

7.62e-05331574CID000190902
DrugIHC-64

CACNA1A CACNA1S ITPR1 ITPR3

7.62e-05331574CID000162753
Drugprinomastat

TNC PRKDC MMP3 MMP8

7.62e-05331574CID000466151
DrugOleandomycin phosphate [7060-74-4]; Down 200; 5uM; HL60; HG-U133A

HSP90B1 SPAST HTR4 ATP10B FRMD4B PASK SKAP2 RAD54L

7.70e-0520015782018_DN
DrugMDL-12330A

TRAF3 HTR4 RPS6KA5 ADCY9 CARD14

9.31e-05661575CID000004024
DrugAD 288

RPS6KA4 RPS6KA5 PRKDC

1.11e-04141573CID000073553
DrugNa2S

CACNA1A ITPR1 ITPR3 PIP5K1B DYNC1H1

1.32e-04711575CID000028015
DrugGF109203X

CACNA1A HSP90B1 RPS6KA4 RPS6KA5 ADCY9 ITPR1 ITPR3 SLC6A2 PLCXD3 MAPK4

1.33e-0434115710CID000002396
DrugD-161 compound

SLC6A2 SLC6A3

1.41e-0431572ctd:C532102
Drug6-fluorodopamine

SLC6A2 SLC6A3

1.41e-0431572CID000122236
DrugMazindol

SLC6A2 SLC6A3

1.41e-0431572DB00579
DrugMethylphenidate

SLC6A2 SLC6A3

1.41e-0431572DB00422
Drug5-deoxy-5-fluoro-myo-inositol

ITPR1 ITPR3

1.41e-0431572CID000195110
DrugDuloxetine

SLC6A2 SLC6A3

1.41e-0431572DB00476
Drug2-(3-methoxyphenyl)-2-(ethylamino)cyclohexanone

SLC6A2 SLC6A3

1.41e-0431572ctd:C569113
DrugVenlafaxine

SLC6A2 SLC6A3

1.41e-0431572DB00285
Drug4-fluoroamphetamine

SLC6A2 SLC6A3

1.41e-0431572ctd:C040639
DrugRadicicol

HSP90B1 DLAT

1.41e-0431572DB03758
DrugSibutramine

SLC6A2 SLC6A3

1.41e-0431572DB01105
DrugRTI-219

SLC6A2 SLC6A3

1.41e-0431572CID010524711
DrugAC1NBCLZ

DLAT MMP3

1.41e-0431572CID004491168
Drug2-(4-bromo-2,5-dimethoxyphenyl)ethylamine

SLC6A2 SLC6A3

1.41e-0431572ctd:C079321
Drug1-phenyl-2-(1-pyrrolidinyl)-1-pentanone

SLC6A2 SLC6A3

1.41e-0431572ctd:C000592273
Drugdifluoropine

SLC6A2 SLC6A3

1.41e-0431572CID000190851
DrugDexmethylphenidate

SLC6A2 SLC6A3

1.41e-0431572DB06701
Drug2-(4-bromo-2,5-dimethoxyphenyl)-N-((2-methoxyphenyl)methyl)ethanamine

SLC6A2 SLC6A3

1.41e-0431572ctd:C000595926
Drug1,4-diazabicyclo[3.3.1]nonane

SLC6A2 SLC6A3

1.41e-0431572CID015140257
Drug5-(2-aminopropyl)benzofuran

SLC6A2 SLC6A3

1.41e-0431572ctd:C000608250
Drug4-methoxymethamphetamine

SLC6A2 SLC6A3

1.41e-0431572ctd:C060169
Drug2-(4-iodo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine

SLC6A2 SLC6A3

1.41e-0431572ctd:C554181
Diseasegraft-versus-host disease (biomarker_via_orthology)

HSPA1A HSPA1B HSPA8

1.33e-0651523DOID:0081267 (biomarker_via_orthology)
Diseaseurate measurement, bone density

RAP1GAP2 TIAM2 ITPR1 ITPR2 SLC6A2 FSIP2 TNFSF13B MOV10L1 ST8SIA2 PLXNA4 PRKDC CADPS2 SKAP2 DNAH11

4.22e-0661915214EFO_0003923, EFO_0004531
DiseaseBipolar Disorder

CACNA1A MAGI1 HSP90B1 HTR4 SLC39A3 ITPR1 SLC6A2 SLC6A3 ST8SIA2 ULK4 PLCXD3 FKBP5

7.32e-0647715212C0005586
DiseaseMajor depression, single episode

HSPA1A HSPA1B HSPA1L

1.10e-0591523C0024517
DiseaseHypoxic Brain Damage

ITPR1 ITPR2

2.64e-0521522C1140716
DiseaseAnoxic Encephalopathy

ITPR1 ITPR2

2.64e-0521522C0003132
DiseaseBrain Hypoxia

ITPR1 ITPR2

2.64e-0521522C1527348
DiseaseAnoxia of brain

ITPR1 ITPR2

2.64e-0521522C0995195
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

ITPR1 ITPR2 ITPR3

2.85e-05121523DOID:1441 (implicated_via_orthology)
Diseaseblood phosphate measurement

RPS6KA5 ANKH ABCC6 ADCY9 SBNO1 PIP5K1B PARP9

3.46e-051741527EFO_0010972
Diseasechronic venous insufficiency, Varicose veins

KCNH8 SKAP2

7.88e-0531522EFO_0007940, HP_0002619
Diseasemajor depressive disorder (is_implicated_in)

HSPA1A HSPA1L FKBP5

8.64e-05171523DOID:1470 (is_implicated_in)
Diseaselevel of Phosphatidylcholine (18:2_18:2) in blood serum

DOCK7 PLXNA4

3.90e-0461522OBA_2045106
Diseaseattention deficit hyperactivity disorder (implicated_via_orthology)

SLC6A2 SLC6A3 ADGRL2

3.99e-04281523DOID:1094 (implicated_via_orthology)
DiseaseSchizophrenia

DOCK4 MAGI1 HTR4 SLC6A2 SLC6A3 SBNO1 ST8SIA2 ULK4 MMP3 CADPS2 HSPA1A HSPA1B HSPA1L

6.78e-0488315213C0036341
DiseaseParkinson Disease

LRRK2 NCAPG2 SLC6A3 HSPA1A

9.91e-04851524C0030567
Diseaseautism spectrum disorder (implicated_via_orthology)

CHD2 ITPR3 SLC6A2 SLC6A3 CADPS2

1.17e-031521525DOID:0060041 (implicated_via_orthology)
Diseaseglucagon measurement

FRMD4B TIAM2 ITPR1 ADGRL2 NLRP13

1.24e-031541525EFO_0008463
DiseaseParkinsonism (is_implicated_in)

LRRK2 HSPA1A

1.41e-03111522DOID:0080855 (is_implicated_in)
DiseaseMajor Depressive Disorder

SLC6A2 MMP8 HSPA1A HSPA1B HSPA1L FKBP5

1.67e-032431526C1269683
DiseaseAL amyloidosis

ULK4 DNAH11

1.68e-03121522MONDO_0019438
DiseaseKawasaki disease (is_implicated_in)

HSPA1A HSPA1L

1.68e-03121522DOID:13378 (is_implicated_in)
DiseaseMood Disorders

HTR4 SLC6A2 SLC6A3 TNFSF13B FKBP5

1.82e-031681525C0525045
Diseasemelanoma

GOPC TNC CAPN1 MMP8 HSPA1A EPB41

1.85e-032481526C0025202
Diseasepallidum volume change measurement

KCNH8 ADCY9

1.98e-03131522EFO_0021494
DiseaseUnipolar Depression

SLC6A2 MMP8 HSPA1A HSPA1B HSPA1L FKBP5

2.30e-032591526C0041696
Diseasemultiple myeloma, monoclonal gammopathy

ULK4 DNAH11

2.30e-03141522EFO_0000203, EFO_0001378
Diseaseapolipoprotein B measurement

SLC44A2 SRPRA ZNF224 ZNF226 ZNF112 ZNF235 ZNF284 MYOF DOCK7 DNAH11

2.37e-0366315210EFO_0004615
Diseasehigh grade glioma (biomarker_via_orthology)

TNC SLC6A3

2.65e-03151522DOID:3070 (biomarker_via_orthology)
Diseasecytokine measurement

MAGI1 RAP1GAP2 ZNF224 ZNF112 STK31 ITPR1 ADGRL2 SKAP2

2.77e-034611528EFO_0004873
Diseaseneutrophil collagenase measurement

MMP8 HSPA1L

3.02e-03161522EFO_0008248
Diseasepartial epilepsy

ADCY9 TBC1D32

3.41e-03171522EFO_0004263
DiseaseMoyamoya Disease

RNF213 ABCC6

3.41e-03171522C0026654
DiseaseAlzheimer disease, polygenic risk score

LRRK2 ZNF223 ZNF112 ZNF230 FSIP2 SBNO1 ULK4 PLCXD3 ZNF222

3.45e-035861529EFO_0030082, MONDO_0004975
Diseaselymphocyte count

CACNA1S TRAF3 SPAST HTR4 RAP1GAP2 ADCY9 ITPR1 ITPR2 SBNO1 TNFSF13B MCM3AP SKAP2 HSPA1A HSPA1B KYNU FKBP5

3.72e-03146415216EFO_0004587
DiseaseMalignant neoplasm of endometrium

ATR FBXW7

3.82e-03181522C0007103
DiseaseCarcinoma in situ of endometrium

ATR FBXW7

3.82e-03181522C0346191
Diseasesystemic lupus erythematosus (is_implicated_in)

TLR5 HSPA1A HSPA1L

4.06e-03621523DOID:9074 (is_implicated_in)
Diseasediet measurement, HOMA-B

MAGI1 PLXNA4

4.26e-03191522EFO_0004469, EFO_0008111
Diseaseuric acid measurement

SHLD2 INTU RPS6KA4 CHD2 ZNF318 ADCY9 MYOF PIP5K1B ADGRL2

4.48e-036101529EFO_0004761

Protein segments in the cluster

PeptideGeneStartEntry
IFDFVTVLGSITDIL

CACNA1A

1631

O00555
LEFKEDFITLFEPSL

ERICH6

221

Q7L0X2
IEFGTSLDEEIILKA

EPB41

116

P11171
KLAEEFFLSTEGTVL

ADAL

161

Q6DHV7
ISDSGFVLKELEVLA

ELMOD3

306

Q96FG2
DIISGEALIELLEKF

TBC1D32

961

Q96NH3
VIFADTLTLLFEGIA

COG4

266

Q9H9E3
FTAILDTLDIFLEIV

CPA1

206

P15085
QLLKVEETFTEELGF

GVINP1

1521

Q7Z2Y8
LIKIEDIFATTLEFE

DNAH11

471

Q96DT5
FIAEFIFLIGIDKTK

ADGRL2

891

O95490
LVFLEGLKSAVDVVF

ELP6

81

Q0PNE2
FRFFKTLDTDLDGVV

CAPN1

686

P07384
SELGETFKFKEAVVL

DESI2

61

Q9BSY9
ETKLEISGDEFLNFL

ASZ1

346

Q8WWH4
VFGVLDKDISAETLL

ATP10B

1161

O94823
DAITTLRGEILFFKD

MMP8

286

P22894
FSLGELKELFILDEA

RAD54L

656

Q92698
KTFGISLEEVLVNEF

ARHGAP36

111

Q6ZRI8
TAAEILFDEVLTFAK

PARP9

441

Q8IXQ6
FDKAFVDVDLLLGEI

GOPC

41

Q9HD26
FVTKLLEDLIFFVAD

ITPR2

471

Q14571
VGFLFLKDDFILEVD

ITPR3

2386

Q14573
IKEAFILSDLFDIGE

NUP205

91

Q92621
FFALLTDVLEIEIKD

HECW2

251

Q9P2P5
KDTVVQSFLVEFLFL

OVOS1

751

Q6IE37
KVSGTEFIIDFLEEK

FAXC

156

Q5TGI0
ATLFFEIELLDFKGE

FKBP5

126

Q13451
TITEFILLGFFKQDE

OR1S1

21

Q8NH92
DTKPIEAELFFFSVL

OR2B3

191

O76000
IAEDFTIKLIDFGSA

PASK

1136

Q96RG2
FEVVKQFVTGIIDSL

MATN2

671

O00339
GVLEESIFFTLDSLK

MOV10L1

196

Q9BXT6
EFIEILFGISLTEVD

MAGEC3

231

Q8TD91
FLTVKEFLDLEQSGT

MAGI1

161

Q96QZ7
IETKLVLSRFEFEGV

ITPR1

666

Q14643
FISTEDLVLKIGDFG

MAPK4

156

P31152
FLVVDGIDKLAFESE

MMRN1

1161

Q13201
IVVGTDTGKLFLFES

CFAP57

211

Q96MR6
LVDLFLVEEIFQTAK

MCM3AP

1216

O60318
FDAVSTLRGEILIFK

MMP3

296

P08254
TFLEDVISGVLRKIF

FSIP2

4621

Q5CZC0
EEFSKVTEGLTDVIL

SYNCRIP

261

O60506
LVAFIISDFESVSKI

ERAP1

246

Q9NZ08
DVSILTIDDGIFEVK

HSPA1B

206

P0DMV9
GTLQKFVDDLFETIF

PLXNA4

1686

Q9HCM2
LLAEIETDKATIGFE

DLAT

251

P10515
LFFVTSDDEFIIKTV

PIP5K1B

126

O14986
DVILEKGEVIDFSSL

KAT14

301

Q9H8E8
GLTAKELEALDEVFT

NENF

116

Q9UMX5
ETIDLLNTGEKLFIF

EVC2

1261

Q86UK5
GKITLLILDEESDIF

LRRK2

146

Q5S007
LSTGEEFALVEEKVL

LHX8

171

Q68G74
ILTIDDGIFEVKATA

HSPA1L

211

P34931
LEELLTEGFKEIFES

GBP7

556

Q8N8V2
VLTDFGLSKEFLTEE

RPS6KA4

176

O75676
VVLTDFGLSKEFVAD

RPS6KA5

191

O75582
SVKFEDFVTALSILL

KCNIP1

116

Q9NZI2
FVDSPIIVDITKDTF

GBA

436

P04062
TEIAIEIAFKLFFGL

INTU

926

Q9ULD6
GTVIALFSVKDEDLD

PCDHAC1

356

Q9H158
LGFIVEKAGESFTEL

P2RX2

241

Q9UBL9
ITSLTLFEEFEKQGI

PGBD5

346

Q8N414
DDKTVLDLAVVLFET

HSP90B1

706

P14625
IKFEFDGIEIDLVFA

PAPOLG

156

Q9BWT3
EVESETIFKLAAFIL

FRMD4B

171

Q9Y2L6
IFGVLTKELLQLFED

ATR

141

Q13535
LFKAVLEDTTLEEAV

CARD14

626

Q9BXL6
EIVKFLQDTLDTLFG

DOCK4

611

Q8N1I0
SLKFEIEIEPIFASL

DOCK7

271

Q96N67
DFTIVFLGVFTVILE

CACNA1S

126

Q13698
EELTAILKFGAEDLF

CHD2

966

O14647
DTVFDKETLFGELSI

C5orf22

66

Q49AR2
GTEETKLLVLDFDVD

FBXW7

691

Q969H0
KVVSFLEKTGFVDET

C1orf112

741

Q9NSG2
EEGFGSVEKVVLLTF

HTR4

11

Q13639
KILIDIIGVDFAFAE

ANKH

351

Q9HCJ1
EEVSILFADIVGFTK

ADCY9

391

O60503
VKLFTESTGVLALED

CADPS2

426

Q86UW7
DLESFQLEISGFLKE

FAM98B

76

Q52LJ0
LLAESVTEVEIFGKA

DYNC1H1

1716

Q14204
VAVLDKVTDFLFLLG

SLC44A2

591

Q8IWA5
IDVVLSAISAFEIFK

HEATR1

531

Q9H583
LFFLQVKEGILSDEI

EZR

101

P15311
DVSILTIDDGIFEVK

HSPA1A

206

P0DMV8
VLDSELFLEKFFLVA

FAM135B

1386

Q49AJ0
VKVVGELLDEAFELA

SDS

106

P20132
LSFTGVTFKIEEVLL

SBNO1

536

A3KN83
DIEGVGLFKESVFEL

CFAP47

3041

Q6ZTR5
ILIDKTSFVSFVGLA

CD37

36

P11049
SKFFELIQGTEIDIF

CMTR1

556

Q8N1G2
KIIEEFVSGLESYIE

FANCD2

91

Q9BXW9
DVFELFLSKKELTEV

LRRC72

46

A6NJI9
DVSILTIEDGIFEVK

HSPA8

206

P11142
AFESFLLFEGEKITI

POLR2J3

6

Q9H1A7
DKIFLILAIAEFIIS

TAS2R42

6

Q7RTR8
KKIDFLLSVVGFAVD

SLC6A2

61

P23975
FETLEVEAKVALEIF

MRPL39

216

Q9NYK5
AFKEFLDLLGDTITL

RAP1GAP2

286

Q684P5
KEFFFSTEDLPEVIL

SLC9C1

6

Q4G0N8
LLGELSKVEGFVSIE

ABCC6

676

O95255
LADVETFVADILKGE

SKAP2

21

O75563
AKEVVIFGAASELFT

HMGCL

121

P35914
LFFVLKSSDVLDILV

HID1

386

Q8IV36
ILDTVFKIFDLDGDE

MICU2

366

Q8IYU8
AFTVFLGDIILLTDV

SHLD2

496

Q86V20
LVVFLIFADISEIEE

ST8SIA2

16

Q92186
IEDIGDIKFSSTEIL

SHOC1

231

Q5VXU9
GTFLFITFLEILAKE

SLC39A3

271

Q9BRY0
EIFLEELTKVGAEEL

RRP1

171

P56182
LKTEFLIEFDGVQSA

SPAST

461

Q9UBP0
FGLELDEITSEKEII

FARSB

31

Q9NSD9
LFIGASILTVLELFD

ASIC1

441

P78348
DESIFSAFLSVVGKL

NCAPD2

1256

Q15021
TFVQAVSKELVGEFL

NCAPG2

6

Q86XI2
FLSFKVDLGISLLEE

C15orf62

146

A8K5M9
AFESFLLFEGEKITI

POLR2J2

6

Q9GZM3
LKVFDLSVEGSLISE

STK31

531

Q9BXU1
DFVELGDFISTVIKL

PLCXD3

296

Q63HM9
GEVTLAEIDVIFKDF

RNF213

1296

Q63HN8
SFFKLIDTIASEIGE

RIN2

16

Q8WYP3
DDTIFIKVIVDTSDL

TRAF3

551

Q13114
GEFIEFLSKARETFL

ZSWIM5

1136

Q9P217
KDVAVVFTEEELGLL

ZNF223

11

Q9UK11
FVLITDILDTFGKLV

VPS35L

231

Q7Z3J2
LEFQKVFLETLEDGI

TIAM2

1151

Q8IVF5
TIEILFSEGLIKALF

MTREX

466

P42285
SLFGEVRKLITDEFV

TRO

571

Q12816
GFSATFEKILESELL

PSD2

136

Q9BQI7
KIDFLLSVIGFAVDL

SLC6A3

66

Q01959
FDSFLVTVVDSGKLL

TNC

1556

P24821
EVLLSADFTGAIKVF

WDR44

891

Q5JSH3
EFLKVDQGTLFELIL

SKP1

91

P63208
IEDVTDEILKLGLFS

SPATA7

371

Q9P0W8
LIDGIVLTKFDTIDD

SRPRA

581

P08240
ISVIIVSELGDKTFF

TMEM165

101

Q9HC07
LALFSVSDKTGLVEF

ATIC

6

P31939
VLKEEGVSFLINTFE

PRKDC

1211

P78527
KDVAVVFTEEELGLL

ZNF234

11

Q14588
KDVAVAFTEEELGLL

ZNF226

11

Q9NYT6
KDVAVVFTEEELGLL

ZNF112

11

Q9UJU3
KDVAVFFTEEELGLL

ZNF230

11

Q9UIE0
KDVAVVFTEEELGLL

ZNF155

11

Q12901
GFVISDDKILEAVTL

TASOR2

2281

Q5VWN6
LGDLFLETFASLVEV

TMEM129

256

A0AVI4
KDVAVVFTEEELGLL

ZNF224

11

Q9NZL3
EEEVLKSLKFSLFIV

TLR5

631

O60602
KVHVFGDELSLVTLF

TNFSF13B

216

Q9Y275
KDVAVAFTEEELGLL

ZNF235

11

Q14590
FEATDLKVEELTALG

ZNF318

2001

Q5VUA4
FASVSDLIDIGKFTL

ZNF781

126

Q8N8C0
GFSFKEDTLLLIAEV

ZHX1-C8orf76

271

Q96EF9
KDVAVIFTEEELGLL

ZNF222

11

Q9UK12
KDVAVVFTEEELGLL

ZNF284

11

Q2VY69
DEFGILETDVTFLLI

TMEM145

166

Q8NBT3
EEFIKITLSAFEAII

ULK4

901

Q96C45
AFESFLLFEGEKKIT

POLR2J

6

P52435
GDVVLFLASFKDITD

KCNH8

121

Q96L42
EVIEKEGDSIAVILF

KYNU

206

Q16719
LLFIIDGFEEIIISE

NLRP13

306

Q86W25
FSSSLGIIVKDFETI

MYOF

61

Q9NZM1