Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

HCN3 HCN2 SCN1A SCN2A SCN3A

1.38e-06261525GO:0005248
GeneOntologyMolecularFunctionsodium channel activity

HCN3 HCN2 SCN1A SCN2A SCN3A

4.66e-05521525GO:0005272
GeneOntologyMolecularFunctionATP hydrolysis activity

DDX47 DDX17 PSMC3 BTAF1 DNAH7 DDX11 KIF3B ATAD1 DDX3Y ASCC3 DNAH5 DNAH8

1.45e-0444115212GO:0016887
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN2A SCN3A

1.48e-04141523GO:0031402
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH7 DNAH5 DNAH8 HTT

1.75e-04371524GO:0045505
GeneOntologyMolecularFunctionATP-dependent activity

DDX47 MYH10 DDX17 MYO1D PSMC3 BTAF1 DNAH7 DDX11 KIF3B ATAD1 DDX3Y ASCC3 DNAH5 DNAH8

2.57e-0461415214GO:0140657
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

DDX47 DDX17 LRRK2 PSMC3 BTAF1 DNAH7 DDX11 TUBB6 KIF3B ATAD1 ERAS DDX3Y GNA15 ASCC3 DNAH5 DNAH8

2.85e-0477515216GO:0017111
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYH10 MYO1D DNAH7 KIF3B DNAH5 DNAH8

2.88e-041181526GO:0003774
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH7 DNAH5 DNAH8

3.24e-04181523GO:0008569
GeneOntologyMolecularFunctionpyrophosphatase activity

DDX47 DDX17 LRRK2 PSMC3 BTAF1 DNAH7 DDX11 TUBB6 KIF3B ATAD1 ERAS DDX3Y GNA15 ASCC3 DNAH5 DNAH8

6.76e-0483915216GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

DDX47 DDX17 LRRK2 PSMC3 BTAF1 DNAH7 DDX11 TUBB6 KIF3B ATAD1 ERAS DDX3Y GNA15 ASCC3 DNAH5 DNAH8

6.85e-0484015216GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

DDX47 DDX17 LRRK2 PSMC3 BTAF1 DNAH7 DDX11 TUBB6 KIF3B ATAD1 ERAS DDX3Y GNA15 ASCC3 DNAH5 DNAH8

6.85e-0484015216GO:0016818
GeneOntologyMolecularFunctionsmall GTPase binding

DOCK3 RAPGEF6 LZTR1 LRRK2 OCRL DOCK5 KIF3B ARHGAP44 DOCK7

8.06e-043211529GO:0031267
GeneOntologyMolecularFunctioncAMP binding

HCN3 HCN2 RAPGEF2

8.80e-04251523GO:0030552
GeneOntologyMolecularFunctionalkali metal ion binding

SCN1A SCN2A SCN3A

9.89e-04261523GO:0031420
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH7 DNAH5 DNAH8

1.23e-03281523GO:0051959
GeneOntologyMolecularFunctionhelicase activity

DDX47 DDX17 BTAF1 DDX11 DDX3Y ASCC3

1.34e-031581526GO:0004386
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN1A SCN2A SCN3A

2.33e-04171513GO:0001518
GeneOntologyCellularComponentaxon

MYH10 MYO1D HCN3 LRRK2 HCN2 ADCY8 NMNAT3 ITPR2 KIF3B SACS SCN1A SCN2A SCN3A DOCK7 WDFY3 HTT EPHB1

2.49e-0489115117GO:0030424
GeneOntologyCellularComponentprotein phosphatase type 2A complex

PPP2R2D PPP2R2B PPP2R2C

2.78e-04181513GO:0000159
GeneOntologyCellularComponentPML body

ATR PATL1 CIITA SIMC1 WDFY3 TOP3A

2.98e-041251516GO:0016605
GeneOntologyCellularComponentHCN channel complex

HCN3 HCN2

3.08e-0441512GO:0098855
GeneOntologyCellularComponentphosphatase complex

PPP2R2D PPP4R3B PPP2R2B PPP2R2C

6.70e-04551514GO:1903293
GeneOntologyCellularComponentprotein serine/threonine phosphatase complex

PPP2R2D PPP4R3B PPP2R2B PPP2R2C

6.70e-04551514GO:0008287
GeneOntologyCellularComponentaxonemal dynein complex

DNAH7 DNAH5 DNAH8

7.56e-04251513GO:0005858
GeneOntologyCellularComponentnuclear body

TBXA2R RBM11 DDX17 ATR PATL1 PPP4R3B CSF1 CIITA CLK3 SCN1A SIMC1 WDFY3 ASCC3 TOP3A NSMCE4A SYMPK

8.47e-0490315116GO:0016604
GeneOntologyCellularComponentcell body

PCSK2 MYH10 MYO1D HCN3 LRRK2 HCN2 ADCY8 NMNAT3 RLBP1 P2RY1 SCN1A SCN3A WDFY3 GRIN3B RAPGEF2 HTT

1.14e-0392915116GO:0044297
GeneOntologyCellularComponentsodium channel complex

SCN1A SCN2A SCN3A

1.18e-03291513GO:0034706
GeneOntologyCellularComponentsomatodendritic compartment

PCSK2 MYH10 MYO1D HCN3 LRRK2 HCN2 ADCY8 NMNAT3 KIF3B P2RY1 SACS SCN1A ARHGAP44 SCN3A WDFY3 GRIN3B RAPGEF2 HTT EPHB1

1.39e-03122815119GO:0036477
GeneOntologyCellularComponentintercalated disc

JUP PIK3CA SCN1A SCN2A

1.49e-03681514GO:0014704
DomainARM-type_fold

DOCK3 USP34 GPRASP1 ATR LRRK2 PSMD2 FHOD3 BTAF1 RALGAPA2 ITPR2 DOCK5 PPP4R3B JUP PIK3CA WDFY3 HTT SYMPK

1.85e-0933914917IPR016024
DomainPP2A_PR55_CS

PPP2R2D PPP2R2B PPP2R2C

1.98e-0641493IPR018067
DomainPP2A_PR55

PPP2R2D PPP2R2B PPP2R2C

1.98e-0641493IPR000009
DomainPR55_2

PPP2R2D PPP2R2B PPP2R2C

1.98e-0641493PS01025
DomainPR55_1

PPP2R2D PPP2R2B PPP2R2C

1.98e-0641493PS01024
DomaincNMP

RAPGEF6 HCN3 HCN2 PNPLA6 RAPGEF2

6.98e-06341495SM00100
DomaincNMP_binding

RAPGEF6 HCN3 HCN2 PNPLA6 RAPGEF2

6.98e-06341495PF00027
DomaincNMP-bd_dom

RAPGEF6 HCN3 HCN2 PNPLA6 RAPGEF2

8.09e-06351495IPR000595
DomainCNMP_BINDING_3

RAPGEF6 HCN3 HCN2 PNPLA6 RAPGEF2

8.09e-06351495PS50042
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A

9.78e-0661493PF11933
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A

9.78e-0661493IPR024583
DomainARM-like

GPRASP1 ATR LRRK2 PSMD2 FHOD3 BTAF1 PPP4R3B JUP WDFY3 HTT SYMPK

1.12e-0527014911IPR011989
DomaincNMP-bd-like

RAPGEF6 HCN3 HCN2 PNPLA6 RAPGEF2

1.23e-05381495IPR018490
Domain-

RAPGEF6 HCN3 HCN2 PNPLA6 RAPGEF2

3.92e-054814952.60.120.10
DomainHEAT

ATR BTAF1 JUP HTT SYMPK

3.92e-05481495PF02985
DomainP-loop_NTPase

DDX47 MYH10 DDX17 MYO1D LRRK2 PSMC3 BTAF1 DNAH7 DDX11 KIF3B ATAD1 CIITA ERAS AK2 DDX3Y GNA15 ASCC3 DNAH5 DNAH8

4.61e-0584814919IPR027417
DomainIQ

MYH10 MYO1D SCN1A SCN2A SCN3A UBE3C

4.62e-05811496SM00015
DomainRmlC-like_jellyroll

RAPGEF6 HCN3 HCN2 PNPLA6 RAPGEF2

5.28e-05511495IPR014710
DomainNa_channel_asu

SCN1A SCN2A SCN3A

5.73e-05101493IPR001696
DomainNa_trans_assoc

SCN1A SCN2A SCN3A

5.73e-05101493IPR010526
DomainNa_trans_assoc

SCN1A SCN2A SCN3A

5.73e-05101493PF06512
Domain-

GPRASP1 ATR LRRK2 PSMD2 BTAF1 JUP WDFY3 HTT SYMPK

7.45e-0522214991.25.10.10
DomainDHR-1_domain

DOCK3 DOCK5 DOCK7

7.83e-05111493IPR027007
DomainDHR_2

DOCK3 DOCK5 DOCK7

7.83e-05111493PS51651
DomainDHR_1

DOCK3 DOCK5 DOCK7

7.83e-05111493PS51650
DomainDHR-2

DOCK3 DOCK5 DOCK7

7.83e-05111493PF06920
DomainDOCK

DOCK3 DOCK5 DOCK7

7.83e-05111493IPR026791
DomainDOCK_C

DOCK3 DOCK5 DOCK7

7.83e-05111493IPR010703
DomainDOCK-C2

DOCK3 DOCK5 DOCK7

7.83e-05111493PF14429
DomainDHR-2

DOCK3 DOCK5 DOCK7

7.83e-05111493IPR027357
DomainIQ_motif_EF-hand-BS

MYH10 MYO1D SCN1A SCN2A SCN3A UBE3C

8.36e-05901496IPR000048
DomainHEAT

ATR BTAF1 JUP HTT SYMPK

9.85e-05581495IPR000357
DomainIQ

MYH10 MYO1D SCN1A SCN2A SCN3A UBE3C

1.00e-04931496PS50096
DomainDynein_heavy_chain_D4_dom

DNAH7 DNAH5 DNAH8

1.70e-04141493IPR024317
DomainDynein_HC_stalk

DNAH7 DNAH5 DNAH8

1.70e-04141493IPR024743
DomainDynein_heavy_dom-2

DNAH7 DNAH5 DNAH8

1.70e-04141493IPR013602
DomainDHC_N2

DNAH7 DNAH5 DNAH8

1.70e-04141493PF08393
DomainMT

DNAH7 DNAH5 DNAH8

1.70e-04141493PF12777
DomainAAA_8

DNAH7 DNAH5 DNAH8

1.70e-04141493PF12780
DomainDHC_fam

DNAH7 DNAH5 DNAH8

2.11e-04151493IPR026983
DomainDynein_heavy

DNAH7 DNAH5 DNAH8

2.11e-04151493PF03028
DomainDynein_heavy_dom

DNAH7 DNAH5 DNAH8

2.11e-04151493IPR004273
DomainIQ

MYH10 MYO1D SCN1A SCN3A UBE3C

2.58e-04711495PF00612
DomainIon_trans_dom

HCN3 HCN2 ITPR2 SCN1A SCN2A SCN3A

3.06e-041141496IPR005821
DomainIon_trans

HCN3 HCN2 ITPR2 SCN1A SCN2A SCN3A

3.06e-041141496PF00520
DomainIon_trans_N

HCN3 HCN2

3.75e-0441492IPR013621
DomainIon_trans_N

HCN3 HCN2

3.75e-0441492PF08412
DomainDOCK_N

DOCK3 DOCK5

6.22e-0451492PF16172
DomainDOCK_N

DOCK3 DOCK5

6.22e-0451492IPR032376
DomainBEX

BEX1 BEX2

6.22e-0451492IPR007623
DomainGLYPICAN

GPC6 GPC4

9.29e-0461492PS01207
DomainGlypican

GPC6 GPC4

9.29e-0461492IPR001863
DomainGlypican_CS

GPC6 GPC4

9.29e-0461492IPR019803
DomainGlypican

GPC6 GPC4

9.29e-0461492PF01153
Domain-

DDX47 DDX17 LRRK2 PSMC3 BTAF1 DNAH7 DDX11 ATAD1 ERAS AK2 DDX3Y GNA15 ASCC3 DNAH5 DNAH8

9.32e-04746149153.40.50.300
DomainAAA

PSMC3 DNAH7 ATAD1 ASCC3 DNAH5 DNAH8

1.05e-031441496SM00382
DomainAAA+_ATPase

PSMC3 DNAH7 ATAD1 ASCC3 DNAH5 DNAH8

1.05e-031441496IPR003593
DomainTPR_11

TTC14 STIP1

1.29e-0371492PF13414
DomainHelicase_C

DDX47 DDX17 BTAF1 DDX3Y ASCC3

1.67e-031071495PF00271
DomainHELICc

DDX47 DDX17 BTAF1 DDX3Y ASCC3

1.67e-031071495SM00490
DomainVillin/Gelsolin

VILL SCIN

1.72e-0381492IPR007122
DomainDHC_N1

DNAH5 DNAH8

1.72e-0381492PF08385
DomainGEL

VILL SCIN

1.72e-0381492SM00262
DomainDynein_heavy_dom-1

DNAH5 DNAH8

1.72e-0381492IPR013594
DomainHelicase_C

DDX47 DDX17 BTAF1 DDX3Y ASCC3

1.74e-031081495IPR001650
DomainHELICASE_CTER

DDX47 DDX17 BTAF1 DDX3Y ASCC3

1.81e-031091495PS51194
DomainHELICASE_ATP_BIND_1

DDX47 DDX17 BTAF1 DDX3Y ASCC3

1.81e-031091495PS51192
DomainDEXDc

DDX47 DDX17 BTAF1 DDX3Y ASCC3

1.81e-031091495SM00487
DomainHelicase_ATP-bd

DDX47 DDX17 BTAF1 DDX3Y ASCC3

1.89e-031101495IPR014001
DomainDEAD_ATP_HELICASE

DDX47 DDX17 DDX3Y

1.90e-03311493PS00039
DomainCNMP_BINDING_1

HCN3 HCN2 PNPLA6

2.08e-03321493PS00888
DomainCNMP_BINDING_2

HCN3 HCN2 PNPLA6

2.08e-03321493PS00889
DomainRNA-helicase_DEAD-box_CS

DDX47 DDX17 DDX3Y

2.28e-03331493IPR000629
DomainWD40_repeat_dom

WDR64 PPP2R2D TAF1C LRRK2 DCAF5 PPP2R2B PPP2R2C WDFY3

2.68e-032971498IPR017986
DomainDEAD/DEAH_box_helicase_dom

DDX47 DDX17 DDX3Y ASCC3

2.76e-03731494IPR011545
DomainDEAD

DDX47 DDX17 DDX3Y ASCC3

2.76e-03731494PF00270
DomainQ_MOTIF

DDX47 DDX17 DDX3Y

3.17e-03371493PS51195
DomainRNA_helicase_DEAD_Q_motif

DDX47 DDX17 DDX3Y

3.17e-03371493IPR014014
DomainMit_uncoupling

SLC25A14 SLC25A30

3.96e-03121492IPR002030
DomainInhibin_asu

BMP8B BMP8A

4.65e-03131492IPR002405
Domain-

WDR64 PPP2R2D TAF1C LRRK2 DCAF5 PPP2R2B PPP2R2C WDFY3

5.33e-0333314982.130.10.10
DomainGelsolin

VILL SCIN

5.40e-03141492PF00626
DomainGelsolin-like_dom

VILL SCIN

5.40e-03141492IPR007123
DomainATPase_dyneun-rel_AAA

DNAH5 DNAH8

5.40e-03141492IPR011704
DomainBEX

BEX1 BEX2

5.40e-03141492PF04538
DomainTF_A-like/BEX

BEX1 BEX2

5.40e-03141492IPR021156
DomainK_chnl_volt-dep_EAG/ELK/ERG

HCN3 HCN2

5.40e-03141492IPR003938
DomainAAA_5

DNAH5 DNAH8

5.40e-03141492PF07728
DomainWD40/YVTN_repeat-like_dom

WDR64 PPP2R2D TAF1C LRRK2 DCAF5 PPP2R2B PPP2R2C WDFY3

5.52e-033351498IPR015943
DomainWD40

WDR64 PPP2R2D LRRK2 DCAF5 PPP2R2B PPP2R2C WDFY3

5.78e-032681497SM00320
DomainPI3/4_kinase_CS

ATR PIK3CA

6.20e-03151492IPR018936
DomainWD40_repeat

WDR64 PPP2R2D LRRK2 DCAF5 PPP2R2B PPP2R2C WDFY3

6.25e-032721497IPR001680
DomainZnf_FYVE_PHD

SPIRE2 ING3 KDM4C MTMR4 WDFY3

6.52e-031471495IPR011011
Domain-

ATR PIK3CA

7.05e-031614921.10.1070.11
DomainPI3Kc

ATR PIK3CA

7.05e-03161492SM00146
Pubmed

Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.

NEB SCN1A SCN2A SCN3A

1.75e-09515241679748
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

NEB SCN1A SCN2A SCN3A

1.75e-09515248812438
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

DOCK3 PALD1 USP34 SPIRE2 RAPGEF6 LZTR1 ARID3A POLR2A NLRX1 BTAF1 RALGAPA2 ITPR2 BMP8B PNPLA6 NUAK1 BTBD7 ARHGAP44 WDFY3 UBE3C TOP3A HTT SYMPK

3.23e-0911051522235748872
Pubmed

SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.

SCN1A SCN2A SCN3A

8.18e-083152323859570
Pubmed

Contribution of cyclooxygenase-1 to thromboxane formation, platelet-vessel wall interactions and atherosclerosis in the ApoE null mouse.

TBXA2R PTGIS PTGS1

8.18e-083152318514659
Pubmed

Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

SCN1A SCN2A SCN3A

8.18e-083152312610651
Pubmed

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

SCN1A SCN2A SCN3A

8.18e-083152318784617
Pubmed

Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.

SCN1A SCN2A SCN3A

8.18e-083152317544618
Pubmed

Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.

SCN1A SCN2A SCN3A

8.18e-083152314973256
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

DDX47 DDX17 MYO1D POLR2A PSMD2 BTAF1 ITPR2 TUBB6 JUP F11R TIAL1 SACS DOCK7 STIP1 ASCC3 QARS1 SCIN MGA NEURL4

1.25e-0710241521924711643
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN2A SCN3A

3.26e-074152317537961
Pubmed

Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.

SCN1A SCN2A SCN3A

3.26e-074152335801810
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN2A SCN3A

3.26e-074152335031483
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN2A SCN3A

3.26e-074152329578003
Pubmed

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

SCN1A SCN2A SCN3A

3.26e-07415238974318
Pubmed

Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.

SCN1A SCN2A SCN3A

8.13e-075152324337656
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN1A SCN2A SCN3A

1.62e-066152323652591
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

SPIRE2 PPFIBP1 TAF1C HCN3 TTC14 PSMC3 DCAF5 KIF3B VILL CCDC47 CLK3 JRK MGA SYMPK

2.22e-066891521436543142
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

DDX47 MYH10 DDX17 RPS6KA4 MYO1D PPFIBP1 PSMD2 LAMC2 ITPR2 PLEK2 TUBB6 JUP PNPLA6 CLK3 DOCK7 ASCC3 MICU2 QARS1 MVP

2.67e-0612571521936526897
Pubmed

HSF1 transcriptional activity is modulated by IER5 and PP2A/B55.

PPP2R2D PPP2R2B PPP2R2C

2.83e-067152325816751
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

MYH10 DDX17 ATR BTAF1 DOCK5 DOCK7 ASCC3 NEURL4

3.23e-06202152833005030
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

MYH10 LZTR1 MYO1D PPP2R2D POLR2A PSMC3 PSMD2 ITPR2 PPP4R3B TUBB6 MTMR4 CCDC47 AK2 STIP1 SCIN NEURL4 SYMPK

3.75e-0610491521727880917
Pubmed

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.

DDX47 DDX17 PCDH11Y PSMC3 PSMD2 TGFBR2 CCDC47 DNAH5 MVP

3.94e-06277152930745168
Pubmed

Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.

DDX17 POLR2A PATL1 JUP DOCK7 DDX3Y RAPGEF2 SYMPK

6.06e-06220152824550385
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN1A SCN2A SCN3A

6.74e-069152316382098
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN2A SCN3A

6.74e-069152315746173
Pubmed

Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development.

PPP2R2D PPP2R2B PPP2R2C

6.74e-069152319762425
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

DDX47 MYH10 DDX17 ACO2 TAF1C POLR2A PSMC3 PSMD2 OCRL PLEK2 TUBB6 JUP PNPLA6 CCDC47 WDFY3 ASCC3 QARS1 MGA MVP

7.65e-0613531521929467282
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

MRPL23 PALD1 RBM11 MYH10 MYO1D HDHD5 ACO2 PSMC3 PSMD2 OCRL ITPR2 ATAD1 CCDC47 MLF1 AK2 STIP1 UBE3C MICU2 NEURL4 TOP3A

8.90e-0614961522032877691
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

MYH10 DDX17 MYO1D ACO2 POLR2A PSMC3 PSMD2 PATL1 TUBB6 JUP LATS1 PIK3CA DDX3Y STIP1 ASCC3 QARS1 MGA MVP

9.35e-0612471521827684187
Pubmed

JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier function.

RAPGEF6 F11R RAPGEF2

9.60e-0610152323885123
Pubmed

EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.

DDX47 MYH10 DDX17 ACO2 PSMC3 PSMD2 TUBB6 JUP SCN2A GPC4 DDX3Y STIP1 QARS1 MVP

1.26e-058031521436517590
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

MYH10 DDX17 ING3 ARID3A MYO1D PSMC3 LAMC2 BRD8 DOCK7 QARS1 MRTFA

1.52e-055061521130890647
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

PPP2R2D HDHD5 NLRX1 DCAF5 NOMO1 PPP4R3B PPP2R2B PNPLA6 ATAD1 CCDC47 UBE3C NSMCE4A

1.56e-056061521236538041
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MYH10 DDX17 MYO1D ACO2 PSMC3 PSMD2 ITPR2 MLXIPL JUP PPP2R2C PNPLA6 SACS SCN2A ARHGAP44 DOCK7 DDX3Y STIP1 PLCL1 RAPGEF2

1.67e-0514311521937142655
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1A SCN2A SCN3A

1.75e-0512152330175250
Pubmed

Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.

SCN1A SCN2A SCN3A

1.75e-051215238169823
Pubmed

Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.

SCN2A SCN3A

1.90e-052152220346423
Pubmed

Brain expressed and X-linked (Bex) proteins are intrinsically disordered proteins (IDPs) and form new signaling hubs.

BEX1 BEX2

1.90e-052152225612294
Pubmed

Activating PIK3CA mutation promotes adipogenesis of adipose-derived stem cells in macrodactyly via up-regulation of E2F1.

E2F1 PIK3CA

1.90e-052152232732866
Pubmed

Hyperpolarization-activated cyclic nucleotide-modulated 'HCN' channels confer regular and faster rhythmicity to beating mouse embryonic stem cells.

HCN3 HCN2

1.90e-052152218033814
Pubmed

Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.

SCN1A SCN2A

1.90e-052152210827969
Pubmed

Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.

SCN1A SCN2A

1.90e-052152219694741
Pubmed

Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.

SCN2A SCN3A

1.90e-052152211245985
Pubmed

Differential expression of two sodium channel subtypes in human brain.

SCN1A SCN2A

1.90e-05215221317301
Pubmed

Bone morphogenetic protein 8A plays a role in the maintenance of spermatogenesis and the integrity of the epididymis.

BMP8B BMP8A

1.90e-05215229463357
Pubmed

The gene encoding bone morphogenetic protein 8B is required for the initiation and maintenance of spermatogenesis in the mouse.

BMP8B BMP8A

1.90e-05215228682296
Pubmed

Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.

SCN2A SCN3A

1.90e-052152223016767
Pubmed

Peripherally derived T regulatory and γδ T cells have opposing roles in the pathogenesis of intractable pediatric epilepsy.

SCN1A IL17RA

1.90e-052152229487082
Pubmed

Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.

SCN2A SCN3A

1.90e-052152227153334
Pubmed

Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.

SCN1A SCN3A

1.90e-052152224990319
Pubmed

Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.

SCN1A SCN2A

1.90e-052152231439038
Pubmed

The PDZ domain of the guanine nucleotide exchange factor PDZGEF directs binding to phosphatidic acid during brush border formation.

RAPGEF6 RAPGEF2

1.90e-052152224858808
Pubmed

E2F1 mediated DDX11 transcriptional activation promotes hepatocellular carcinoma progression through PI3K/AKT/mTOR pathway.

E2F1 DDX11

1.90e-052152232332880
Pubmed

Functional Intraregional and Interregional Heterogeneity between Myenteric Glial Cells of the Colon and Duodenum in Mice.

POLR2A E2F1

1.90e-052152236319118
Pubmed

Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.

SCN1A SCN2A

1.90e-052152215249644
Pubmed

Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.

SCN1A SCN3A

1.90e-052152227690330
Pubmed

The human uncoupling proteins 5 and 6 (UCP5/SLC25A14 and UCP6/SLC25A30) transport sulfur oxyanions, phosphate and dicarboxylates.

SLC25A14 SLC25A30

1.90e-052152231356773
Pubmed

The protective role of bone morphogenetic protein-8 in the glucocorticoid-induced apoptosis on bone cells.

BMP8B BMP8A

1.90e-052152221277400
Pubmed

The E3 ubiquitin ligase UBE3C enhances proteasome processivity by ubiquitinating partially proteolyzed substrates.

PSMD2 UBE3C

1.90e-052152224158444
Pubmed

Trophectoderm-specific expression of the X-linked Bex1/Rex3 gene in preimplantation stage mouse embryos.

BEX1 BEX2

1.90e-052152211835573
Pubmed

E2F1, ARID3A/Bright and Oct-2 factors bind to the Epstein-Barr virus C promoter, EBNA1 and oriP, participating in long-distance promoter-enhancer interactions.

ARID3A E2F1

1.90e-052152222302879
Pubmed

Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.

SCN1A SCN3A

1.90e-052152223965409
Pubmed

SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.

SCN1A SCN2A

1.90e-052152230693367
Pubmed

Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.

SCN1A SCN2A

1.90e-052152229649454
Pubmed

Cloning and expression pattern of a spermatogenesis-related gene, BEX1, mapped to chromosome Xq22.

BEX1 BEX2

1.90e-052152211989783
Pubmed

Human BMP8A suppresses luteinization of rat granulosa cells via the SMAD1/5/8 pathway.

BMP8B BMP8A

1.90e-052152231940275
Pubmed

BEX1 supports the stemness of hepatoblastoma by facilitating Warburg effect in a PPARγ/PDK1 dependent manner.

BEX1 BEX2

1.90e-052152237715024
Pubmed

Suppression of cell migration by phospholipase C-related catalytically inactive protein-dependent modulation of PI3K signalling.

PIK3CA PLCL1

1.90e-052152228710365
Pubmed

Role for thromboxane receptors in angiotensin-II-induced hypertension.

TBXA2R PTGS1

1.90e-052152214718360
Pubmed

P2Y1 receptor blockade normalizes network dysfunction and cognition in an Alzheimer's disease model.

ITPR2 P2RY1

1.90e-052152229724785
Pubmed

Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.

SCN1A SCN2A

1.90e-052152233096315
Pubmed

BQ788 reveals glial ETB receptor modulation of neuronal cholinergic and nitrergic pathways to inhibit intestinal motility: Linked to postoperative ileus.

POLR2A E2F1

1.90e-052152237198101
Pubmed

Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.

SCN1A SCN2A

1.90e-052152226311622
Pubmed

BEX1 is an RNA-dependent mediator of cardiomyopathy.

BEX1 BEX2

1.90e-052152229192139
Pubmed

HCN3 ion channels: roles in sensory neuronal excitability and pain.

HCN3 HCN2

1.90e-052152231290157
Pubmed

Circuit-specific enteric glia regulate intestinal motor neurocircuits.

POLR2A E2F1

1.90e-052152234593632
Pubmed

The developmental changes of Na(v)1.1 and Na(v)1.2 expression in the human hippocampus and temporal lobe.

SCN1A SCN2A

1.90e-052152221377452
Pubmed

Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma.

BEX1 BEX2

1.90e-052152216818640
Pubmed

Phosphatidic acid-dependent localization and basal de-phosphorylation of RA-GEFs regulate lymphocyte trafficking.

RAPGEF6 RAPGEF2

1.90e-052152232600317
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

DOCK3 RAPGEF6 ING3 ACACB DOCK5 LATS1 SCN1A MGA NEURL4 MRTFA

2.12e-054301521035044719
Pubmed

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.

USP34 MYO1D PSMD2 PATL1 ITPR2 TUBB6 SIMC1 SYMPK

2.15e-05262152836880596
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN1A SCN2A SCN3A

2.27e-0513152315123669
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

GPRASP1 MYH10 HCN3 HCN2 TUBB6 KIF3B SPHKAP ARHGAP44 DOCK7 STIP1 PLCL1 WDFY3 RAPGEF2 MGA NEURL4

2.28e-059631521528671696
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

MYH10 ACACB MYO1D PPFIBP1 PATL1 OCRL DNAH7 TUBB6 LATS1 SIMC1 MLF1 UBE3C MGA NEURL4

2.45e-058531521428718761
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

MYH10 DDX17 POLR2A PSMC3 PSMD2 NOMO1 TUBB6 STIP1 UBE3C ASCC3 QARS1 SYMPK

2.59e-056381521233239621
Pubmed

An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers.

ING3 KDM4C BRD8

2.88e-0514152328981838
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH7 DNAH5 DNAH8

2.88e-051415239373155
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK3 DOCK5 DOCK7

2.88e-0514152312432077
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

DDX17 CMTR1 ACACB TUBB6 JUP PPP2R2C ASCC3 MGA SYMPK

2.96e-05357152937059091
Pubmed

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.

MYH10 DDX17 ACO2 PSMD2 JUP GLDC AK2 DDX3Y STIP1 QARS1

3.17e-054511521036168627
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

DDX47 USP34 LZTR1 ING3 TAF1C POLR2A RALGAPA2 DCAF5 TUBB6 BRD8 PNPLA6 RTL9 WDFY3 ASCC3 RAPGEF2 MGA

3.28e-0511161521631753913
Pubmed

Confirmation of quantitative trait loci for alcohol preference in mice.

SCN1A SCN2A SCN3A

3.58e-051515239726281
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

DDX47 MRPL23 GPRASP1 MYH10 PPP2R2D TAF1C PSMC3 PSMD2 JUP ATAD1 GLDC DOCK7 STIP1 ASCC3 NEURL4

3.72e-0510051521519615732
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

DDX47 DDX17 HDHD5 POLR2A PSMC3 PSMD2 BTAF1 NOMO1 DDX11 TUBB6 TIAL1 CCDC47 GMDS DDX3Y UBE3C ASCC3 QARS1

3.82e-0512571521737317656
Pubmed

Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.

ATR PPP2R2D PSMC3 PPP2R2B DOCK7

4.13e-0587152517148452
Pubmed

USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.

DDX47 MYH10 DDX17 MYO1D PSMC3 PSMD2 TUBB6 CCDC47 CLK3 GMDS DDX3Y

4.16e-055651521133567341
Pubmed

Human transcription factor protein interaction networks.

RBM11 MYH10 ING3 ARID3A ACACB MYO1D ACO2 PSMC3 PSMD2 E2F1 PATL1 DCAF5 JUP BRD8 STIP1 QARS1 MGA SYMPK

5.60e-0514291521835140242
Pubmed

Voltage-gated sodium channels in taste bud cells.

SCN2A SCN3A

5.68e-053152219284629
Pubmed

Association of SCN1A, SCN2A, and UGT2B7 Polymorphisms with Responsiveness to Valproic Acid in the Treatment of Epilepsy.

SCN1A SCN2A

5.68e-053152232185219
InteractionPLEC interactions

MXRA5 DDX17 ATR LRRK2 NOMO1 JUP PPP2R2B LATS1 GLDC MLF1 STIP1 RAPGEF2 QARS1 DNAH5 HTT

9.45e-0743015215int:PLEC
InteractionTOP3B interactions

DOCK3 PALD1 USP34 RBM11 MYH10 SPIRE2 RAPGEF6 LZTR1 ARID3A MYO1D POLR2A NLRX1 BTAF1 PATL1 RALGAPA2 ITPR2 BMP8B PNPLA6 NUAK1 BTBD7 ARHGAP44 GPC4 WDFY3 UBE3C QARS1 TOP3A HTT SYMPK

4.67e-06147015228int:TOP3B
InteractionRAB11A interactions

TBXA2R PALD1 MYH10 SPIRE2 ACACB ATR MYO1D PPFIBP1 LRRK2 OCRL RALGAPA2 ITPR2 TGFBR2 JUP MTMR4 CCDC47 STIP1 WDFY3 HTT

1.63e-0583015219int:RAB11A
InteractionPTEN interactions

DDX47 MYH10 ACACB MYO1D ACO2 BEX1 POLR2A PSMD2 E2F1 PATL1 DNAAF8 JUP LATS1 CCDC47 GPC4 STIP1 HSD17B1 ASCC3 MVP EPHB1

2.31e-0592915220int:PTEN
InteractionCCDC8 interactions

DDX17 MYO1D POLR2A PSMD2 BTAF1 ITPR2 TUBB6 JUP F11R SACS DOCK7 STIP1 ASCC3 QARS1 SCIN NEURL4

3.74e-0565615216int:CCDC8
InteractionGPR182 interactions

ATR NLRX1 BTAF1 NOMO1 DOCK5 ATAD1 CCDC47 SIMC1 WDFY3 UBE3C MICU2 HTT SYMPK

4.25e-0545515213int:GPR182
InteractionMGARP interactions

ATR HDHD5 NLRX1 SLC25A14 SLC25A30 BTAF1 CCDC47 WDFY3 MICU2

4.88e-052221529int:MGARP
Cytoband19p13.3

TBXA2R ARID3A PLEKHJ1 HCN2 GNA15 GRIN3B

1.47e-04237152619p13.3
Cytoband17p13

MYH10 ITGAE NEURL4

1.97e-0434152317p13
Cytoband12p11

ITPR2 DDX11

3.86e-049152212p11
GeneFamilySodium voltage-gated channel alpha subunits

SCN1A SCN2A SCN3A

1.65e-05910731203
GeneFamilyWD repeat domain containing|Protein phosphatase 2 regulatory subunits

PPP2R2D PPP2R2B PPP2R2C

8.71e-05151073696
GeneFamilyDEAD-box helicases

DDX47 DDX17 DDX11 DDX3Y

1.09e-04421074499
GeneFamilyDyneins, axonemal

DNAH7 DNAH5 DNAH8

1.29e-04171073536
GeneFamilyBrain expressed X-linked family

BEX1 BEX2

3.43e-04510721217
GeneFamilyGlypicans

GPC6 GPC4

5.12e-0461072572
GeneFamilyGelsolin/villins

VILL SCIN

9.49e-0481072950
GeneFamilyCyclic nucleotide gated channels

HCN3 HCN2

1.51e-03101072250
GeneFamilyBone morphogenetic proteins|Astacins

BMP8B BMP8A

1.84e-03111072455
GeneFamilyDNA helicases

DDX11 ASCC3

4.45e-031710721167
GeneFamilyWD repeat domain containing

WDR64 PPP2R2D DCAF5 PPP2R2B PPP2R2C WDFY3

4.67e-032621076362
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

DOCK3 GPRASP1 RAPGEF6 PPFIBP1 HCN3 LRRK2 TTC14 LAMC2 FHOD3 OCRL NEB NLN PPP2R2B PPP2R2C F11R NUAK1 SCN1A SCN2A SCN3A BEX2 SCIN EPHB1

4.49e-07110615222M39071
CoexpressionGSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_DN

MYH10 POLR2A RALGAPA2 DDX11 MTMR4 BRD8 TIAL1 SIMC1 HSD17B1

2.47e-061981529M3352
CoexpressionGSE22886_NAIVE_CD8_TCELL_VS_DC_DN

ACO2 PTGS1 TUBB6 PNPLA6 CCDC47 WDFY3 RAPGEF2 HTT

2.29e-052001528M4492
CoexpressionGSE19825_NAIVE_VS_IL2RAHIGH_DAY3_EFF_CD8_TCELL_DN

LZTR1 ING3 PSMC3 PIDD1 BTAF1 ZNF707 YDJC MRTFA

2.29e-052001528M4300
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

LZTR1 HDHD5 TUBB6 MTMR4 KIF3B PNPLA6 HERC3 IL17RA

2.19e-071821528c98da2db197b1531204e116600ff51891e5c17af
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK2 GPRASP1 BEX1 OCRL SPHKAP SCN3A GPC4 BEX2

2.81e-071881528e99e3765b48392c987cf0c5ccbded0655637d7b7
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 MXRA5 FHOD3 GLDC SCN2A SCN3A DOCK7 EPHB1

2.92e-0718915283a295c215b5c18e7c673f92b7af5be523421682c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 MXRA5 FHOD3 PTGS1 F11R GLDC SCN2A SCN3A

3.30e-0719215280bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-cDC2|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PALD1 B3GNTL1 LRRK2 HCN2 P2RY1 CIITA SACS

1.76e-0616715271bd0aa7a3c8649f342bb856cf861c4c5984ad889
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-pDC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PALD1 WDR64 RPS6KA4 ARID3A DNAAF8 GNA15 EPHB1

2.79e-061791527bbd4f8e988ef3f343aaedbc992b70f2bb6aff5f6
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_plasma-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

MYO1D NOMO1 NUAK1 GLDC GMDS DDX3Y HSD17B1

2.90e-0618015278e96f8646c002768b272359af485dc0ab57e0ccd
ToppCellIPF-Myeloid-DC_Langerhans|World / Disease state, Lineage and Cell class

PALD1 MYO1D PLEK2 DOCK5 PPP2R2B CIITA GNA15

3.12e-0618215270e8cfbd8ea196f27a227dbb4d2eb93bc48d27922
ToppCellIPF-Myeloid-DC_Langerhans|IPF / Disease state, Lineage and Cell class

PALD1 MYO1D PLEK2 DOCK5 PPP2R2B CIITA GNA15

3.47e-061851527f8ee3cb2aa9ec70f9ce8797be2b155da27ef6464
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

DOCK3 ACACB PPFIBP1 ACO2 FHOD3 SPHKAP PLCL1

3.73e-06187152778cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 FHOD3 GLDC SCN2A SCN3A DOCK7 EPHB1

3.73e-061871527e3095455d2f255854f339f6b05fa87852af0700f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 PPFIBP1 LRRK2 DNAH7 GPC4 GMDS DNAH5

4.28e-061911527d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK2 GPRASP1 BEX1 OCRL SPHKAP GPC4 BEX2

4.28e-061911527657297cd19d05a7e7bb74fc3a086fbd95f47aae4
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

DOCK3 ACACB ACO2 FHOD3 SPHKAP MLF1 PLCL1

4.43e-061921527ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 MXRA5 PTGS1 F11R GLDC SCN3A EPHB1

4.59e-061931527e7012f7b53971972299db34fa51ff51a4e4987fe
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 MXRA5 PTGS1 F11R SCN2A SCN3A SCIN

4.74e-061941527be869e186386d03ebb670971dd24fa656b4b0edf
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1D LRRK2 LAMC2 DNAH7 JUP GPC4 DNAH5

4.74e-061941527e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 MXRA5 PTGS1 F11R SCN2A SCN3A SCIN

4.74e-0619415274d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCellproximal-Epithelial-Neuroendocrine|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PCSK2 BEX1 NEB HCN2 RLBP1 SPHKAP SCN3A

5.42e-0619815275dea6078488d584513c0bdbf5bba54877310b54a
ToppCellproximal-Epithelial-Neuroendocrine-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PCSK2 BEX1 NEB HCN2 RLBP1 SPHKAP SCN3A

5.42e-06198152700ccf3020667cf2130bc354b441b65c0b1b0e862
ToppCellproximal-3-Epithelial-Neuroendocrine|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PCSK2 BEX1 NEB HCN2 RLBP1 SPHKAP SCN3A

5.42e-061981527a6bc043faf68468d46bac441cf7447c236c7bae4
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 PPFIBP1 JUP F11R GLDC SCN2A SCIN

5.61e-061991527a4ebb0598e9a0c9f6e39a0db6d0623654c2a7d88
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 MXRA5 DDX17 PPFIBP1 GLDC SCN2A SCIN

5.61e-0619915273cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK3 PCSK2 BEX1 SPHKAP SCN2A SCN3A

1.80e-0515915267747cef94c55144fddcd024a7495318357f1351b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 MXRA5 DDX17 GLDC SCN2A SCIN

1.86e-0516015267064af50fc10e3ea03badf415306222b74db0f95
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 MXRA5 DDX17 F11R BNIPL SCN2A

2.62e-051701526928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCellControl-MAIT|Control / Disease group and Cell class

RBM11 RAPGEF6 HCN3 HCN2 NMNAT3 BEX2

2.80e-051721526552bc62e8e8bb0ac1cd0452f4410a3af087787eb
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BEX1 SLC25A30 MATN4 ADCY8 RLBP1 SACS

2.89e-0517315262b448acd5e584f24567204c31b8d74715e92f32a
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BEX1 SLC25A30 MATN4 ADCY8 RLBP1 SACS

2.89e-0517315265086edc29c5a6137ca09877929a1317f9739c801
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PPFIBP1 BEX1 MATN4 RLBP1 SCN1A BEX2

3.28e-051771526d05497d2c80a66ec6a4e1733fea3a5534877a6a7
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK2 OCRL TUBB6 SCN1A SCN3A DDX3Y

3.28e-0517715261dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCellCOVID-19-Heart-Lymph_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PALD1 PPFIBP1 RALGAPA2 DOCK5 TGFBR2 SCN3A

3.28e-051771526326fde0734ef0d7272693966d346ca479b9d8147
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK2 OCRL TUBB6 SCN1A SCN3A DDX3Y

3.28e-051771526426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PALD1 MYH10 PPFIBP1 DOCK5 TGFBR2 SCN3A

3.39e-051781526ad3de3e03a401dac64431a541899445262246347
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ACACB FHOD3 PPP2R2B SCN2A ARHGAP44 SCN3A

3.50e-051791526d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PCSK2 HCN2 PPP2R2B SCN1A SCN2A SCN3A

3.50e-051791526af0b54c9ea0b6e4210f22dbb6e88ecd3276a5f86
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Pulmonary_neuroendocrine|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PCSK2 BEX1 SPHKAP SCN2A SCN3A SCIN

3.61e-05180152657689ccbbd44c0e78e061edd87d3102c5f2dcc9a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BEX1 ITGAE CIITA SPHKAP SCN2A GNA15

3.61e-0518015266ac62bf1251978c8c12e715f7b73144fca619794
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK3 BEX1 PPP2R2B PPP2R2C SCN2A BEX2

3.61e-0518015267d3d5608647b6e684e8e185993d106a38c53e76a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MXRA5 FHOD3 GLDC SCN2A SCN3A DOCK7

3.61e-051801526788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK2 BEX1 SCN1A SPHKAP SCN2A BEX2

3.61e-051801526f6a2208960d0df1500c974cc44c3c054cd7475a9
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PALD1 PPFIBP1 DOCK5 TGFBR2 SPHKAP SCN3A

3.72e-051811526e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCellEpithelial-lung_neuroendocrine_cell_(PNEC)|World / Lineage, Cell type, age group and donor

DOCK3 PCSK2 BEX1 SPHKAP SCN2A SCN3A

3.84e-05182152657bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 MXRA5 FHOD3 GLDC SCN2A DOCK7

3.84e-051821526f96095b81188b52db8fcfca4837129cfcd9bd7b7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIBP1 LRRK2 NMNAT3 GPC4 GMDS WDFY3

3.95e-051831526738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PALD1 MYH10 PPFIBP1 DOCK5 TGFBR2 SCN3A

3.95e-0518315264d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 FHOD3 SCN2A ARHGAP44 SCN3A SCIN

3.95e-051831526b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK2 BEX1 SCN1A SPHKAP SCN2A BEX2

4.20e-05185152670de48988c1f8e0809afc8092b663aa439d8e528
ToppCellCOVID-19-Neuronal_cells-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

PALD1 PPFIBP1 RALGAPA2 DOCK5 SCN3A EPHB1

4.20e-0518515264a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCellCOVID-19-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

PALD1 PPFIBP1 RALGAPA2 DOCK5 SCN3A EPHB1

4.20e-05185152636ce23893915f5c380cca39b2c33a516edf31c3a
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCDH11Y LRRK2 PTGIS ITPR2 SPHKAP BMP8A

4.20e-0518515265a0340c25196453f19e424d346efbf66d2c53ac3
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PALD1 MYH10 PPFIBP1 DOCK5 TGFBR2 SCN3A

4.33e-05186152640070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK2 BEX1 OCRL PPP2R2B SPHKAP SCN3A

4.33e-0518615264bb54043f944a979db91bde9a86dd66f498c7658
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PCSK2 BEX1 FHOD3 RLBP1 PPP2R2B SCN3A

4.33e-051861526cf96f880e6e22189593ce1357c55e65c34644559
ToppCellPCW_07-8.5-Neuronal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PCSK2 FHOD3 RLBP1 BMP8B PPP2R2B SCN1A

4.33e-0518615267a4bb42f3f6a27b463e48eafc587d9ab3386f2fb
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PALD1 PPFIBP1 DOCK5 TGFBR2 SPHKAP SCN3A

4.33e-05186152620340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK2 BEX1 SCN1A SPHKAP SCN2A BEX2

4.46e-0518715267b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 GLDC SCN2A SCN3A DOCK7 SCIN

4.46e-0518715262d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCell15-Airway-Epithelial-Neuroendocrine|Airway / Age, Tissue, Lineage and Cell class

PCSK2 BEX1 MLXIPL SPHKAP SCN3A BEX2

4.46e-051871526a7d2f30fe0f19e63d44603ece9890acd11b45e52
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1D PPFIBP1 LRRK2 NMNAT3 GPC4 GMDS

4.60e-05188152663a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_Erythro-Mega-Mega-Mast|lymph-node_spleen / Manually curated celltypes from each tissue

TBXA2R MRPL23 E2F1 PTGS1 NMNAT3 STIP1

4.60e-0518815268e80e0714883e5c5e372d933682c5b55ebef7e62
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FHOD3 GLDC SCN2A SCN3A DOCK7 SCIN

4.60e-0518815264154f4787483c7e076e87a187733a9f666742c3d
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-pDC|lymph-node_spleen / Manually curated celltypes from each tissue

PALD1 RPS6KA4 ARID3A TUBB6 GNA15 EPHB1

4.73e-0518915266c2ace61a7d62bcf7e76b73e2da8b722d03e713b
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

DOCK3 ACO2 FHOD3 SPHKAP MLF1 PLCL1

4.73e-0518915269c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PPFIBP1 LRRK2 DNAH7 GPC4 GMDS WDFY3

4.73e-051891526904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FHOD3 GLDC SCN2A SCN3A DOCK7 SCIN

4.73e-05189152690aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

PPFIBP1 RALGAPA2 PTGIS PTGS1 ITPR2 GMDS

4.73e-05189152675c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

PPFIBP1 RALGAPA2 PTGIS PTGS1 ITPR2 GMDS

4.73e-051891526c81787a8c662db5d7814c583dd64562857629e81
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-bronchial_smooth_muscle_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 BEX1 BOK SCN2A ARHGAP44 SCIN

4.73e-0518915264dc32b463546bbe7250dddd281b92ad17ec22da1
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Airway_Smooth_Muscle|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 BEX1 BOK SCN2A ARHGAP44 SCIN

4.73e-0518915260d06bf0d7191d13a1c4f30a7881e7ea1093bfd6f
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCSK2 BEX1 FHOD3 PPP2R2B SCN2A BEX2

4.87e-051901526bdbfaced785db79ff965f332759be258dbf743cf
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 RALGAPA2 DOCK5 TGFBR2 SPHKAP EPHB1

4.87e-051901526876bd2eb9ed2624cb23bdcf6b989e4fa34d099e3
ToppCell(2)_5-FU-(1)_VE-Cad+_vascular_cells|World / Stress and Cell class

RALGAPA2 PTGS1 TGFBR2 JUP BOK F11R

4.87e-0519015266b391b8a3ffcbdec3acaf242bc52fc3fc9da77c8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 RALGAPA2 DOCK5 TGFBR2 SPHKAP EPHB1

4.87e-051901526be9f36127028f52ca5fc1b32ba15a6c26aad69ac
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 RALGAPA2 DOCK5 TGFBR2 SPHKAP EPHB1

4.87e-05190152609a8855901c3c9332dbaab3e40166485b696d0f1
ToppCelltumor_Lung-Myeloid_cells-CD207+CD1a+_LCs|Myeloid_cells / Location, Cell class and cell subclass

PALD1 MYO1D PLEK2 DOCK5 PPP2R2B GNA15

4.87e-05190152658a6ab70737d719ca9725ac087f20dfe9be0463e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 MXRA5 DDX17 F11R BNIPL SCIN

4.87e-051901526078f4be52fa4cc8dd9c8d7a2b6d9631c3d902285
ToppCellfacs-Pancreas-Endocrine-3m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK2 GPRASP1 OCRL SPHKAP GPC4 BEX2

5.02e-051911526b3de0393d6510543533cd851e47a0f95739a0e4e
ToppCell15-Trachea-Epithelial-Neuroendocrine|Trachea / Age, Tissue, Lineage and Cell class

PCSK2 BEX1 NEB SCN2A SCN3A BEX2

5.02e-05191152676311fa5f3ae9bb27cf04387a8c92300f2888c28
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 MXRA5 PTGS1 F11R SCN2A SCIN

5.17e-05192152640f44ac4ab673ee6156abdd2074a60b9de3281ad
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD207+CD1a+_LCs|Myeloid_cells / Location, Cell class and cell subclass

PALD1 PPFIBP1 GPC6 PLEK2 PPP2R2B GNA15

5.17e-051921526f18da8db573e584c8b90df0814afcf020360108e
ToppCell11.5-Airway-Epithelial-Epithelial|Airway / Age, Tissue, Lineage and Cell class

BEX1 FHOD3 PPP2R2B PPP2R2C SCN2A SCN3A

5.17e-051921526a77d3692ff02ef7e066a9bd9e22725055a25c4d4
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK2 DDX17 TTC14 MLXIPL P2RY1 BEX2

5.17e-0519215261304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 MXRA5 PTGS1 F11R GLDC SCIN

5.17e-0519215269e031bf93eb8757fdd0cc22f01b44e48f85532d5
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

RAPGEF6 DDX17 POLR2A BTAF1 DDX3Y PLCL1

5.17e-05192152647646d7e4990be85072987f92bf18d52f8da752e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 MXRA5 PTGS1 F11R GLDC SCIN

5.17e-0519215263d777d07878269b87ec7e1f06489cae7c989d633
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D122|Adult / Lineage, Cell type, age group and donor

PCSK2 LRRK2 MLXIPL SCN1A GPC4 DNAH5

5.17e-05192152606013a07e3a873b1d1c0451643c528593ac32a9c
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

ATRN USP34 ATR LATS1 WDFY3 MGA

5.32e-051931526abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCSK2 BEX1 FHOD3 PPP2R2B SCN2A BEX2

5.32e-0519315268851275bcf4ecd6e87a91c8784fc5d76d246ff3b
ToppCellfacs-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX17 ITPR2 JUP CLK3 DDX3Y IL17RA

5.32e-051931526a6a864644e1b80b7417ea0a27281e79068a3fd3d
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYO1D HCN2 DOCK5 BOK PLCL1 CNDP1

5.47e-051941526cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMC2 JUP SCN2A SCN3A DOCK7 SCIN

5.47e-05194152646070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPIRE2 MXRA5 PPP2R2B F11R SCN2A ARHGAP44

5.47e-0519415264579b4a44f7c731553a284843c296866027d7c0e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMC2 JUP SCN2A SCN3A DOCK7 SCIN

5.47e-051941526abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PALD1 MYO1D PTGS1 PLEK2 PPP2R2B CIITA

5.47e-051941526e56c6e5c9b7d287ae94566b561e21cec2055f83d
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PALD1 MYO1D PTGS1 PLEK2 PPP2R2B CIITA

5.63e-05195152685fee07d71c0393ea42bcf1130566dff4a62f507
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK2 MLXIPL SPHKAP DDX3Y ASCC3 MGA

5.63e-0519515263e519cffa6144a62b06124642a14c9ff39b76554
ToppCell11.5-Distal-Epithelial-Neuroendocrine|Distal / Age, Tissue, Lineage and Cell class

PCSK2 BEX1 PPP2R2B SCN3A BEX2 SCIN

5.63e-051951526eda6ebe52c48bd6a9044886e75f584f46c2556e7
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK2 MLXIPL SPHKAP DDX3Y ASCC3 MGA

5.63e-0519515267796ea9247f4c63762f0de8490fed08b9717fa23
ToppCelldroplet-Tongue|droplet / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEK2 JUP BOK BNIPL GNA15 QARS1

5.63e-051951526e460b09ae354b579ce552acebdaa5877a6e62343
DrugCarteolol hydrochloride [51781-21-6]; Up 200; 12.2uM; HL60; HT_HG-U133A

USP34 DDX17 TAF1C NEB BTBD7 MLF1 GMDS TOP3A MVD SYMPK

8.53e-07198151101340_UP
DrugCephapirin sodium salt [24356-60-3]; Up 200; 9uM; MCF7; HT_HG-U133A

TAF1C PIDD1 LAMC2 NEB PTGS1 ITPR2 TGFBR2 GMDS GNA15 RAPGEF2

8.93e-07199151106790_UP
DrugViomycin sulfate [37883-00-4]; Down 200; 5.2uM; HL60; HT_HG-U133A

TAF1C NEB PTGS1 DOCK5 BTBD7 HERC3 WDFY3 RAPGEF2 HTT

6.93e-0619715192979_DN
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

PPP2R2D ITPR2 PPP2R2B PPP2R2C

2.69e-07121454DOID:1441 (implicated_via_orthology)
Diseaseneurodegenerative disease (implicated_via_orthology)

ACO2 LRRK2 PSMD2 NMNAT3 LATS1 PNPLA6 HTT

7.85e-061451457DOID:1289 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN2A SCN3A

1.36e-05101453DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN2A SCN3A

1.36e-05101453DOID:0080422 (implicated_via_orthology)
Diseaseinterleukin 17 receptor A measurement

HDHD5 GAB4 IL17RA

1.86e-05111453EFO_0008175
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN2A SCN3A

2.48e-05121453DOID:0060170 (implicated_via_orthology)
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A SCN2A RAPGEF2

3.21e-05131453C0751122
Diseaseresponse to methotrexate, neurotoxicity

GPC6 PNPLA6 PLCL1

1.06e-04191453EFO_0011057, GO_0031427
DiseaseEpilepsy, Atonic

SCN1A JRK

1.43e-0441452C0086236
DiseaseEpilepsy, Tonic

SCN1A JRK

1.43e-0441452C0086241
DiseaseGeneralized convulsive epilepsy

SCN1A JRK

1.43e-0441452C0311334
DiseaseSymptomatic Generalized Epilepsy

SCN1A JRK

1.43e-0441452C0270854
DiseaseGeneralized Nonconvulsive Seizure Disorder

SCN1A JRK

1.43e-0441452C0017332
DiseaseEpilepsy, Akinetic

SCN1A JRK

1.43e-0441452C0347869
Diseaseanxiety disorder (implicated_via_orthology)

SCN1A SCN2A SCN3A

1.67e-04221453DOID:2030 (implicated_via_orthology)
Diseaseinterleukin-17 receptor A measurement

HDHD5 IL17RA

2.38e-0451452EFO_0801718
DiseaseCrohn's disease

USP34 RPS6KA4 ACO2 LRRK2 ADCY8 KIF3B DOCK7 PTCD2 PLCL1

3.47e-044411459EFO_0000384
Diseasepappalysin-1 measurement

USP34 PSMD2

3.55e-0461452EFO_0802845
DiseaseEpilepsy, Generalized

SCN1A JRK

3.55e-0461452C0014548
DiseaseSeizure, Febrile, Simple

SCN1A SCN2A

4.96e-0471452C0149886
DiseaseSeizure, Febrile, Complex

SCN1A SCN2A

4.96e-0471452C0751057
DiseaseEarly Childhood Epilepsy, Myoclonic

SCN1A RAPGEF2

6.59e-0481452C0393695
DiseaseIdiopathic Myoclonic Epilepsy

SCN1A RAPGEF2

6.59e-0481452C0338478
DiseaseSymptomatic Myoclonic Epilepsy

SCN1A RAPGEF2

6.59e-0481452C0338479
DiseaseBenign Infantile Myoclonic Epilepsy

SCN1A RAPGEF2

6.59e-0481452C0751120
DiseaseMyoclonic Encephalopathy

SCN1A RAPGEF2

6.59e-0481452C0438414
Diseaseproteoglycan 3 measurement

USP34 PSMD2

6.59e-0481452EFO_0802970
DiseaseMyoclonic Absence Epilepsy

SCN1A RAPGEF2

6.59e-0481452C0393703
Diseaseright ventricular systolic volume measurement

FHOD3 TIAL1 MLF1

6.78e-04351453EFO_0021815
DiseaseFebrile Convulsions

SCN1A SCN2A

8.44e-0491452C0009952
DiseaseMyoclonic Epilepsy

SCN1A RAPGEF2

8.44e-0491452C0014550
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN2A

8.44e-0491452C3502809
DiseaseEpilepsy, Myoclonic, Infantile

SCN1A RAPGEF2

1.05e-03101452C0917800
DiseaseParkinson disease

LRRK2 OCRL ITGAE DDX11 TIAL1 SCN2A RTL9

1.08e-033211457MONDO_0005180
Diseasequality of life during menstruation measurement, acne

FHOD3 NLN

1.28e-03111452EFO_0003894, EFO_0009366
DiseaseMyoclonic Astatic Epilepsy

SCN1A RAPGEF2

1.28e-03111452C0393702
Diseasechronotype measurement

DOCK3 PCSK2 USP34 PPP2R2D ACO2 LAMC2 GPC6 ADCY8 PPP2R2B P2RY1 PLCL1 QARS1

1.42e-0388214512EFO_0008328
Diseasecigarettes per day measurement

SPIRE2 CMTR1 BTAF1 ADCY8 MLXIPL KIF3B SCN2A BMP8A

1.50e-034381458EFO_0006525
Diseasesodium measurement

MLXIPL BTBD7 SCN2A PLCL1

1.70e-031031454EFO_0009282
Diseasephosphoglycerides measurement

MLXIPL DOCK7 YDJC

1.71e-03481453EFO_0022291
Diseasereticulocyte count

ATRN USP34 SPIRE2 ARID3A ATR MYO1D PSMD2 ADCY8 PLEK2 DOCK5 MLXIPL GMDS YDJC

1.99e-03104514513EFO_0007986
Diseasewhole-brain volume, Alzheimer's disease biomarker measurement

UBE3C MICU2

2.10e-03141452EFO_0005089, EFO_0006514
Diseasetrimethylamine-N-oxide measurement

ITPR2 UBE3C

2.10e-03141452EFO_0010541
Diseasesulfate measurement

P2RY1 HTT

2.10e-03141452EFO_0007864
Diseasereticulocyte measurement

ATRN USP34 SPIRE2 ARID3A ATR MYO1D PSMD2 ADCY8 PLEK2 DOCK5 MLXIPL PIK3CA YDJC

2.13e-03105314513EFO_0010700
Diseaseheart failure

E2F1 OCRL TIAL1 GNA15 SYMPK

2.25e-031851455EFO_0003144
DiseaseMMR-related febrile seizures

SCN1A SCN2A

2.41e-03151452EFO_0006519
Diseasequinate measurement

KDM4C LRRK2

2.41e-03151452EFO_0021167
DiseaseT-Cell Lymphoma

KDM4C MGA

2.75e-03161452C0079772
Diseaseresponse to hydrochlorothiazide, systolic blood pressure change measurement

TAF1C DDX11

2.75e-03161452EFO_0005202, EFO_0006944
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

SCN1A SCN2A

2.75e-03161452C0393706
Diseaseuterine fibroid

DOCK5 NLN MTMR4 TOP3A MRTFA

3.09e-031991455EFO_0000731
Diseasecreatine kinase measurement

NEB CSF1 MRTFA

3.09e-03591453EFO_0004534
DiseaseBenign neoplasm of stomach

ATR PIK3CA

3.11e-03171452C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

ATR PIK3CA

3.11e-03171452C0496905
DiseaseCarcinoma in situ of stomach

ATR PIK3CA

3.11e-03171452C0154060
Diseasemonocyte percentage of leukocytes

PSMD2 MLXIPL KIF3B CSF1 TIAL1 CIITA GNA15 IL17RA WDFY3 NEURL4

3.38e-0373114510EFO_0007989
Diseaseankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis

RPS6KA4 LRRK2 ADCY8 KIF3B PTCD2 PLCL1

3.46e-032951456EFO_0000384, EFO_0000676, EFO_0000729, EFO_0003898, EFO_0004268
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

SCN1A SCN2A

3.48e-03181452HP_0002373
DiseaseProstatic Neoplasms

ATR PCDH11Y MATN4 PLEK2 TGFBR2 JUP PIK3CA HSD17B1 MGA

3.50e-036161459C0033578
DiseaseMalignant neoplasm of prostate

ATR PCDH11Y MATN4 PLEK2 TGFBR2 JUP PIK3CA HSD17B1 MGA

3.50e-036161459C0376358
Diseaseurate measurement, bone density

WDR64 B3GNTL1 PPFIBP1 HCN2 ITPR2 DOCK5 BOK DNAH8 EPHB1

3.62e-036191459EFO_0003923, EFO_0004531
Diseasetriglycerides to total lipids in medium VLDL percentage

MLXIPL DOCK7 STIP1

3.72e-03631453EFO_0022335
Diseasecholesterol to total lipids in medium VLDL percentage

MLXIPL DOCK7 STIP1

3.72e-03631453EFO_0022239
Diseasecholesteryl esters to total lipids in medium VLDL percentage

MLXIPL DOCK7 STIP1

3.89e-03641453EFO_0022253
Diseaseobesity (implicated_via_orthology)

PSMC3 ITPR2 BMP8B JUP BMP8A

4.28e-032151455DOID:9970 (implicated_via_orthology)
Diseasealpha-tocopherol measurement

KDM4C SCN3A

4.30e-03201452EFO_0007898
Diseasemean platelet volume

POLR2A LRRK2 PSMD2 DCAF5 DOCK5 MLXIPL BRD8 DOCK7 STIP1 MVP MRTFA HTT

4.61e-03102014512EFO_0004584
DiseaseInfiltrating duct carcinoma of female breast

RPS6KA4 ATR

4.74e-03211452C3165106
Diseasegastric ulcer

JUP JRK

4.74e-03211452EFO_0009454
DiseaseStomach Carcinoma

ATR PIK3CA

4.74e-03211452C0699791
Diseasetriglycerides to total lipids in very small VLDL percentage

MLXIPL DOCK7 STIP1

4.81e-03691453EFO_0022341

Protein segments in the cluster

PeptideGeneStartEntry
LRPDRVAMQDATAQM

ACO2

91

Q99798
SVLPRFVVLEMINDM

ADCY8

376

P40145
VMMLTERVAEAQRFA

DDX47

396

Q9H0S4
MDLMVEATPRRVFAN

PPP2R2B

156

Q00005
MDLMVEVSPRRIFAN

PPP2R2C

156

Q9Y2T4
MTRNARPNIVLLMAD

ARSH

1

Q5FYA8
GEPQARMREENMERI

BEX1

71

Q9HBH7
IRSTAEFQRDIMLMF

BRD8

766

Q9H0E9
RVLPDMVSLRVMDVQ

CIITA

1066

P33076
DFLQAMNDIRPSAMR

SPATA5

601

Q8NB90
MNDIRPSAMREIAID

SPATA5

606

Q8NB90
VQLFDLMRRMLEFDP

CLK3

591

P49761
LMRRMLEFDPAQRIT

CLK3

596

P49761
MDLMVEASPRRIFAN

PPP2R2D

166

Q66LE6
MEVLRRSSVFAAEIM

BOK

1

Q9UMX3
RNEEMLVGRSSFPMQ

RBM11

111

P57052
RVQEAMAKEPMARSC

ERAS

201

Q7Z444
FNMRPRELVDVMKNA

ITPR2

2066

Q14571
FPRMRAMSLVSNEGD

ITPR2

2626

Q14571
FLRMVPQGRRMVEEV

PALD1

361

Q9ULE6
MFRNERAIRFVVMVT

ACACB

286

O00763
RPVMIITEFMENGAL

EPHB1

691

P54762
EVMFMATRELLRIPQ

PATL1

716

Q86TB9
TMNLRARLDFQTPAM

P2RY1

281

P47900
AARMSPFVRQMDFAI

PNPLA6

631

Q8IY17
IQDLEMFQPGRMHRV

IL17RA

536

Q96F46
RPFEFETMRQFLMGL

MATN4

46

O95460
GEMVPSRQAFESMLR

LZTR1

711

Q8N653
REMVHADVELMRTNP

GMDS

356

O60547
ENDDLFMMPRIVNVT

MGA

2641

Q8IWI9
MSYQDPRREQMAAAA

LATS1

141

O95835
GLMVLEPRFNVETMA

PPFIBP1

836

Q86W92
FIDAMLMVAERLEGP

GPC4

291

O75487
VLELFQPSELRAMMV

HERC3

921

Q15034
LLREMQQMASRPFAS

ATRN

1316

O75882
FPRTVRQAEMLDDLM

AK2

101

P54819
FRMGPREQRVDMTVI

BNIPL

181

Q7Z465
LNVLARMMRPVSDQV

CCDC47

231

Q96A33
PDFQRAKDFISNMMR

ITGAE

216

P38570
IEQLPMDLRDRFTEM

ING3

11

Q9NXR8
SLVQPMEQGIRRDFM

JRK

326

O75564
QFRTVAMMVPDRQII

DNAH8

1966

Q96JB1
RPMMDVAFVQFLASV

NOMO1

491

Q15155
EDPRMMAFFDSLVRR

DCAF5

411

Q96JK2
IMTFRPSMEEFREFN

KDM4C

16

Q9H3R0
RFRAESVVPARMAEM

MVD

226

P53602
NIVVEAMKAFPMSER

LRRK2

251

Q5S007
DRPGRAAVARSAMMQ

RPS6KA4

386

O75676
RAMIEAMERLQIPFS

GNA15

91

P30679
REAVAQAMVLEMFRE

NLRX1

571

Q86UT6
VEFSPSMVREFVMQE

PPP4R3B

391

Q5MIZ7
FVNATFIREMLMRLV

PTGS1

101

P23219
FQKRELPQMMDEVGR

DDX11

676

Q96FC9
LEEFPMMRRAFETVA

HCN3

526

Q9P1Z3
AMMTRRQDVLPNSDF

RALGAPA2

1021

Q2PPJ7
ARDPMNRMEIFRLNT

JUP

571

P14923
IRQDNERVLFAPMRM

MVP

36

Q14764
VEQMRRPDFMDALQG

PIK3CA

736

P42336
VPLRMIDSVESRDMF

MTMR4

71

Q9NYA4
RAMLLVGRFMEETAN

ATR

2001

Q13535
ELVNRIPAEDMNAFM

HTT

2121

P42858
PDTFIRQQIMALRVM

GPC6

456

Q9Y625
TELFDQMARPAACMV

SLC2A11

396

Q9BYW1
LASNPVDVVRTRMMN

SLC25A30

216

Q5SVS4
LRSIADPAEQMVMVI

E2F1

251

Q01094
GDMEQIRRENPMIFN

DOCK3

386

Q8IZD9
LAFNMLMDRPLEEAV

DOCK5

796

Q9H7D0
LFPVRIGDMRIMENN

DOCK7

751

Q96N67
FLLVQDIMEDTMRFR

CSF1

86

P09603
DIMEDTMRFRDNTPN

CSF1

91

P09603
DPATRDFVVMRARMM

BTAF1

666

O14981
GSEAPFIMRRNTAMQ

GAB4

236

Q2WGN9
VVGTVRMLQAFLPDM

HSD17B1

116

P14061
PQARMREENMERIGE

BEX2

76

Q9BXY8
FIMGLFDRMVPVSVE

DNAH7

1781

Q8WXX0
LMANPRELRIQDMDF

FHOD3

791

Q2V2M9
RADLVMSFVNMVERD

BMP8A

101

Q7Z5Y6
DRMVPSAHNRLMEQL

DNAAF8

301

Q8IYS4
DLVRLRMVRMSNVPD

BTBD7

596

Q9P203
SQLRPMMSELEERAR

LAMC2

1136

Q13753
EADRMLDMGFEPQIR

DDX17

326

Q92841
EADRMLDMGFEPQIR

DDX3Y

346

O15523
RADLVMSFVNMVERD

BMP8B

101

P34820
NMPLVETIAAMERRV

SLC22A20P

511

A6NK97
TMFRFPLRNAEMAKV

SACS

2696

Q9NZJ4
PMMRRAFETVAIDRL

HCN2

646

Q9UL51
GMNVMEFTRAILTPR

MYH10

386

P35580
VMTNRPLRDNEMFEI

NEURL4

351

Q96JN8
ANMDFVFDRMFTNPR

CMTR1

241

Q8N1G2
FRSVAMMVPDRQIII

DNAH5

2101

Q8TE73
FQPMNIFLRQEIDRM

DNAH5

4386

Q8TE73
EEPRRVSMQVVRMAG

PIDD1

486

Q9HB75
MVRDSMAAAFRPSNR

PTCD2

1

Q8WV60
LMPARAMVLVNVTDV

PCDH11Y

366

Q9BZA8
PMTSNAVRMEAVERN

F11R

221

Q9Y624
MVRARDTASPIGAFM

GRIN3B

556

O60391
RVRTSFLENMIRMAP

GPRASP1

1211

Q5JY77
MAFCRPMTETRADVQ

RTL9

26

Q8NET4
RDRPMEESLLLFEAM

QARS1

376

P47897
IGDFLDSMNRRIMET

SPHKAP

636

Q2M3C7
EIRQVVRMTSANMDP

RAPGEF6

1046

Q8TEU7
KRRAMADPEVQQIMS

STIP1

486

P31948
ASAVDMMELYNRLPR

LCMT1

276

Q9UIC8
MMELYNRLPRAEVSR

LCMT1

281

Q9UIC8
MRVTVVAEENPFSMA

SCIN

261

Q9Y6U3
LVAAMQPRMLVTFDE

PSMD2

821

Q13200
FITREVVVDLAMPMA

PTGIS

356

Q16647
GVPSEQRQMLRDYMA

TAF1C

806

Q15572
TVDELRMAFPLLDMV

HDHD5

156

Q9BXW7
PRDFLFSVMFEQMER

MICU2

106

Q8IYU8
LSRQPAEMAAELGMR

PLEKHJ1

11

Q9NW61
MMFGFVLDIPERSQR

SIMC1

691

Q8NDZ2
TARYMAPEVLESRMN

TGFBR2

421

P37173
MLMVNPDRRATIEDI

NUAK1

286

O60285
RAMPAQLRRMEESHQ

NSMCE4A

246

Q9NXX6
RIQMEDRFMASNPSK

SCN3A

1871

Q9NY46
PITHQRFDQMRDMFD

MLXIPL

741

Q9NP71
EQARRPLSVATDNMM

ARHGAP44

486

Q17R89
VSQLPMGRDSREMLF

MRTFA

161

Q969V6
MGRDSREMLFLAEQP

MRTFA

166

Q969V6
VRIMDRMENDFLPSL

OCRL

551

Q01968
MDFLEDPSQRQRAMS

SCN1A

701

P35498
RIQMEERFMASNPSK

SCN1A

1886

P35498
FLDSDDVMMPQRVRL

B3GNTL1

111

Q67FW5
DVMMPQRVRLQHEAA

B3GNTL1

116

Q67FW5
DREPESARMQRAQMA

ARID3A

46

Q99856
QDLDSAIMRRMPTRF

ATAD1

241

Q8NBU5
VDFPITDVLQMMGRA

ASCC3

1676

Q8N3C0
RQELFRMMAVAADTL

CNDP1

71

Q96KN2
PGDLMLMNQDFISRR

C10orf120

291

Q5SQS8
CIPETRRRMEMAFNT

NLN

256

Q9BYT8
ASVNMDPALMFRTRK

RAPGEF2

911

Q9Y4G8
LASNPVDVVRTRMMN

SLC25A14

251

O95258
MDMAQEPVTFRDVAI

ZNF707

1

Q96C28
VHPLREAIDMRENMQ

PLCL1

891

Q15111
MLMEENFLRPVGVRS

PLEK2

186

Q9NYT0
MFERLASQALEPMVL

WDFY3

926

Q8IZQ1
REEFPDRIMNTFSVM

TUBB6

156

Q9BUF5
SMMIRPEARYRAENI

KIF3B

646

O15066
LTPFEMLMQDIRARN

SPIRE2

276

Q8WWL2
MPNEEARARIMQIHS

PSMC3

356

P17980
TRAEIQELAMVPRMI

POLR2A

511

P24928
MRQMIRSFSEPFGRD

MLF1

26

P58340
QFRIPMEMTRVDLRN

MRPL23

41

Q16540
RIQMEERFMASNPSK

SCN2A

1876

Q99250
MSRPRMRLVVTADDF

YDJC

1

A8MPS7
QFMEIPSMDRRELFF

TTC14

106

Q96N46
RKMVDMLQDSFPARF

RLBP1

221

P12271
ANIARQRPMFMSEVI

SYMPK

261

Q92797
PEDRAFSRAAMEMAL

TOP3A

16

Q13472
APDLMQIMEAVLGRR

VILL

216

O15195
AAQQRPRDSEVEMMA

TBXA2R

231

P21731
NLMQLFIAQRPDMRE

USP34

2901

Q70CQ2
MRQTFSPFGQIMEIR

TIAL1

221

Q01085
DSLNVALPMRMLEVF

UBE3C

161

Q15386
RMSTRDRNMAIPFPD

WDR64

611

B1ANS9
AAFFAVRESLVRMMP

GLDC

331

P23378
SMPEFMANLRLRFEK

MYO1D

21

O94832
AENMVRTLPASMLRN

MXRA5

191

Q9NR99
AMANETPDFMRARNA

NEB

6026

P20929
AGIRMLDQPFMTDII

PCSK2

236

P16519
NPITNMHLRMFEVAR

NMNAT3

16

Q96T66