Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

ARAP3 TIAM1 MYCBP2 ARHGEF7 DOCK7 ARHGAP20 PLEKHG5 DENND4C TBCD ARAP1

1.33e-055077210GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

ARAP3 TIAM1 MYCBP2 ARHGEF7 DOCK7 ARHGAP20 PLEKHG5 DENND4C TBCD ARAP1

1.33e-055077210GO:0030695
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

TIAM1 MYCBP2 ARHGEF7 DOCK7 PLEKHG5 DENND4C

1.86e-04231726GO:0005085
GeneOntologyMolecularFunctionangiotensin receptor binding

ZBTB16 ARAP1

5.66e-0410722GO:0031701
DomainPH

AFAP1 ARAP3 TIAM1 ARHGEF7 SKAP1 PLEKHA2 ARHGAP20 PLEKHG5 ARAP1

1.50e-06278749SM00233
DomainPH_DOMAIN

AFAP1 ARAP3 TIAM1 ARHGEF7 SKAP1 PLEKHA2 ARHGAP20 PLEKHG5 ARAP1

1.54e-06279749PS50003
DomainPH_domain

AFAP1 ARAP3 TIAM1 ARHGEF7 SKAP1 PLEKHA2 ARHGAP20 PLEKHG5 ARAP1

1.59e-06280749IPR001849
DomainPH_dom-like

AFAP1 ARAP3 TIAM1 ARHGEF7 SKAP1 PLEKHA2 WDFY3 ARHGAP20 PLEKHG5 ARAP1

6.70e-064267410IPR011993
Domain-

AFAP1 ARAP3 TIAM1 ARHGEF7 SKAP1 PLEKHA2 ARHGAP20 PLEKHG5 ARAP1

2.34e-053917492.30.29.30
DomainPH

AFAP1 ARAP3 TIAM1 ARHGEF7 SKAP1 PLEKHA2 ARAP1

3.40e-05229747PF00169
DomainZINC_FINGER_C2H2_2

ZXDC SCRT2 ZNF703 ZBTB16 ZNF532 ZNF398 ZNF79 ZSCAN16 ZNF839 ZNF564 ZNF441

2.25e-047757411PS50157
DomainZINC_FINGER_C2H2_1

ZXDC SCRT2 ZNF703 ZBTB16 ZNF532 ZNF398 ZNF79 ZSCAN16 ZNF839 ZNF564 ZNF441

2.30e-047777411PS00028
DomainZnf_C2H2-like

ZXDC SCRT2 ZNF703 ZBTB16 ZNF532 ZNF398 ZNF79 ZSCAN16 ZNF839 ZNF564 ZNF441

2.83e-047967411IPR015880
DomainZnf_C2H2

ZXDC SCRT2 ZNF703 ZBTB16 ZNF532 ZNF398 ZNF79 ZSCAN16 ZNF839 ZNF564 ZNF441

3.11e-048057411IPR007087
DomainZnF_C2H2

ZXDC SCRT2 ZNF703 ZBTB16 ZNF532 ZNF398 ZNF79 ZSCAN16 ZNF839 ZNF564 ZNF441

3.21e-048087411SM00355
Domain-

ZXDC SCRT2 ZNF703 ZBTB16 ZNF532 ZNF398 ZNF79 ZSCAN16 ZNF564 ZNF441

3.32e-0467974103.30.160.60
DomainRA

ARAP3 ARHGAP20 ARAP1

3.88e-0436743PF00788
DomainZnf_C2H2/integrase_DNA-bd

ZXDC SCRT2 ZNF703 ZBTB16 ZNF532 ZNF398 ZNF79 ZSCAN16 ZNF564 ZNF441

3.95e-046947410IPR013087
DomainRho_GTPase_activation_prot

ARAP3 ARHGAP20 PLXNB2 ARAP1

4.12e-0488744IPR008936
DomainRA

ARAP3 ARHGAP20 ARAP1

4.21e-0437743PS50200
DomainRA_dom

ARAP3 ARHGAP20 ARAP1

5.31e-0440743IPR000159
DomainLeu-rich_rpt_4

NLRC5 PPP1R42

6.83e-0410742IPR025875
DomainLRR_4

NLRC5 PPP1R42

6.83e-0410742PF12799
DomainRhoGAP

ARAP3 ARHGAP20 ARAP1

1.91e-0362743SM00324
DomainRhoGAP

ARAP3 ARHGAP20 ARAP1

2.00e-0363743PF00620
DomainDH_1

TIAM1 ARHGEF7 PLEKHG5

2.00e-0363743PS00741
DomainInterferon_alpha/beta/delta

IFNA7 IFNA10

2.03e-0317742IPR000471
DomainInterferon

IFNA7 IFNA10

2.03e-0317742PF00143
DomainIFabd

IFNA7 IFNA10

2.03e-0317742SM00076
DomainINTERFERON_A_B_D

IFNA7 IFNA10

2.03e-0317742PS00252
DomainRHOGAP

ARAP3 ARHGAP20 ARAP1

2.09e-0364743PS50238
DomainRhoGAP_dom

ARAP3 ARHGAP20 ARAP1

2.09e-0364743IPR000198
Domain-

ARAP3 ARHGAP20 ARAP1

2.09e-03647431.10.555.10
DomainRhoGEF

TIAM1 ARHGEF7 PLEKHG5

2.49e-0368743SM00325
DomainRhoGEF

TIAM1 ARHGEF7 PLEKHG5

2.70e-0370743PF00621
DomainDH_2

TIAM1 ARHGEF7 PLEKHG5

2.70e-0370743PS50010
DomainDH-domain

TIAM1 ARHGEF7 PLEKHG5

2.81e-0371743IPR000219
Domain-

TIAM1 ARHGEF7 PLEKHG5

2.81e-03717431.20.900.10
DomainEPHD

JADE1 RAI1

3.40e-0322742PS51805
DomainPHD

DIDO1 JADE1 RAI1

5.31e-0389743SM00249
DomainZnf_PHD

DIDO1 JADE1 RAI1

5.65e-0391743IPR001965
DomainArfGap

ARAP3 ARAP1

5.87e-0329742SM00105
DomainArfGap

ARAP3 ARAP1

5.87e-0329742PF01412
DomainARFGAP

ARAP3 ARAP1

5.87e-0329742PS50115
DomainArfGAP

ARAP3 ARAP1

5.87e-0329742IPR001164
DomainZF_PHD_2

DIDO1 JADE1 RAI1

6.37e-0395743PS50016
DomainZF_PHD_1

DIDO1 JADE1 RAI1

6.55e-0396743PS01359
Domainzf-C2H2_6

SCRT2 ZBTB16 ZNF532 ZNF79 ZNF564

8.14e-03314745PF13912
PathwayREACTOME_RHOA_GTPASE_CYCLE

ARAP3 TIAM1 ARHGEF7 ARHGAP20 PLEKHG5 ARAP1

1.37e-05149506M41805
PathwayREACTOME_CDC42_GTPASE_CYCLE

ARAP3 TIAM1 ARHGEF7 DOCK7 ARHGAP20 ARAP1

1.71e-05155506M41808
PathwayREACTOME_RAC1_GTPASE_CYCLE

ARAP3 TIAM1 ARHGEF7 DOCK7 ARHGAP20 ARAP1

4.50e-05184506M41809
PathwayREACTOME_RHOA_GTPASE_CYCLE

ARAP3 ARHGEF7 ARHGAP20 PLEKHG5 ARAP1

1.42e-04142505MM15576
PathwayREACTOME_CDC42_GTPASE_CYCLE

ARAP3 DOCK7 ARHGAP20 ARAP1

3.38e-0494504MM15598
PathwayREACTOME_RAC1_GTPASE_CYCLE

ARAP3 ARHGEF7 DOCK7 ARHGAP20 ARAP1

3.75e-04175505MM15599
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PCNX2 CDR2L TANC2 ZXDC ARAP3 KIAA0513 MYCBP2 PER1 NAV2 ZNF398 NLRC5 WDFY3 JADE1 ZNF839 PLXNB2 PLEKHG5 ABTB2 RAI1 TBCD ARAP1

2.46e-131105772035748872
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PCNX2 ODF2L ZBTB16 SLC41A3 ZNF532 MYCBP2 RPAIN ARID5B KCNMA1 NLRC5 PLEKHA2 GALNT7 ZNF839 RAI1 TBCD ARAP1

1.36e-071489771628611215
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

ZNF703 ODF2L MYCBP2 ARHGEF7 ATG2B CKAP5 DOCK7 MDH1 DENND4C RAI1 MOB2

1.81e-07645771125281560
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AFAP1 ZNF532 ARHGEF7 NAV2 DIDO1 JADE1 ARHGAP20 PLEKHG5 RAI1 ARAP1

2.68e-07529771014621295
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ZNF532 MYCBP2 ARID5B ATG2B CKAP5 DOCK7 PLEKHA2 MDH1 DENND4C

3.77e-0741877934709266
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CDR2L TANC2 ZBTB16 TIAM1 MYCBP2 CKAP5 DOCK7 NAV2 PLEKHA2 ABTB2 DENND4C MOB2

4.13e-07861771236931259
Pubmed

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.

C2CD4B C2CD4A ARAP1

2.26e-061277321873549
Pubmed

C2CD4A/B variants in the predisposition of lung cancer in the Chinese Han population.

C2CD4B C2CD4A

4.84e-06277235212842
Pubmed

Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis.

C2CD4B C2CD4A

4.84e-06277233492421
Pubmed

Tiam1 and betaPIX mediate Rac-dependent endothelial barrier protective response to oxidized phospholipids.

TIAM1 ARHGEF7

4.84e-06277217219408
Pubmed

A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression.

C2CD4B C2CD4A

4.84e-06277229625024
Pubmed

A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.

C2CD4B C2CD4A

1.45e-05377220818381
Pubmed

A genome-wide association study confirms previously reported loci for type 2 diabetes in Han Chinese.

C2CD4B C2CD4A

1.45e-05377221799836
Pubmed

Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice.

C2CD4B C2CD4A

1.45e-05377227329800
Pubmed

Nucleotide sequence of a portion of human chromosome 9 containing a leukocyte interferon gene cluster.

IFNA7 IFNA10

1.45e-0537726181262
Pubmed

A novel gene family induced by acute inflammation in endothelial cells.

C2CD4B C2CD4A

1.45e-05377215527968
Pubmed

Secretome screening reveals immunomodulating functions of IFNα-7, PAP and GDF-7 on regulatory T-cells.

GDF7 IFNA7

1.45e-05377234408239
Pubmed

Per1/Per2-Igf2 axis-mediated circadian regulation of myogenic differentiation.

PER1 PAX7

2.89e-05477234009269
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

TANC2 ARAP3 TFB1M TIAM1 ARHGEF7 DOCK7 ARHGAP20 PLEKHG5 ARAP1 MOB2

3.40e-05916771032203420
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TANC2 MYCBP2 ARHGEF7 CKAP5 DOCK7 KCNMA1 DIDO1 EXOG WDFY3 RAI1

5.18e-05963771028671696
Pubmed

Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices.

ARAP3 ARAP1

7.22e-05677211804589
Pubmed

PRMT7 Preserves Satellite Cell Regenerative Capacity.

PAX7 PRMT7

7.22e-05677226854227
Pubmed

An Islet-Targeted Genome-Wide Association Scan Identifies Novel Genes Implicated in Cytokine-Mediated Islet Stress in Type 2 Diabetes.

ARAP3 PAMR1

7.22e-05677226018251
Pubmed

PI3K signaling through the dual GTPase-activating protein ARAP3 is essential for developmental angiogenesis.

ARAP3 ARAP1

1.01e-04777220978237
Pubmed

Heritability and genome-wide association analysis of renal sinus fat accumulation in the Framingham Heart Study.

TIAM1 ARHGAP20

1.01e-04777222044751
Pubmed

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.

TANC2 ARHGEF7 ARID5B CKAP5 PLEKHA2 ABTB2

1.96e-0437877634315543
Pubmed

Effect of interferon-alpha on immediate early gene expression of murine cytomegalovirus.

IFNA7 IFNA10

2.63e-04117728389790
Pubmed

Type I interferon dependence of plasmacytoid dendritic cell activation and migration.

IFNA7 IFNA10

2.63e-041177215795237
Pubmed

Transgenic expression of IFN-alpha in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration.

IFNA7 IFNA10

2.63e-04117729794439
Pubmed

Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis.

IFNA7 IFNA10

2.63e-041177218835032
Pubmed

Structural and functional neuropathology in transgenic mice with CNS expression of IFN-alpha.

IFNA7 IFNA10

2.63e-041177210448195
Pubmed

High-affinity binding of 125I-labelled mouse interferon to a specific cell surface receptor.

IFNA7 IFNA10

2.63e-04117726444699
Pubmed

Recombinant rabies virus expressing IFNα1 enhanced immune responses resulting in its attenuation and stronger immunogenicity.

IFNA7 IFNA10

2.63e-041177225310498
Pubmed

The mouse IFN-alpha (Ifa) locus: correlation of physical and linkage maps by in situ hybridization.

IFNA7 IFNA10

2.63e-04117723456887
Pubmed

IFN-alpha can both protect against and promote the development of type 1 diabetes.

IFNA7 IFNA10

2.63e-041177219120292
Pubmed

Mechanism of SUMOylation-Mediated Regulation of Type I IFN Expression.

IFNA7 IFNA10

2.63e-041177236681180
Pubmed

Transcriptome Analysis of Cardiac Hypertrophic Growth in MYBPC3-Null Mice Suggests Early Responders in Hypertrophic Remodeling.

ZBTB16 XIRP2

2.63e-041177230410445
Pubmed

Type I interferon production by tertiary lymphoid tissue developing in response to 2,6,10,14-tetramethyl-pentadecane (pristane).

IFNA7 IFNA10

3.15e-041277216565497
Pubmed

AAV2-mediated combined subretinal delivery of IFN-α and IL-4 reduces the severity of experimental autoimmune uveoretinitis.

IFNA7 IFNA10

3.15e-041277222685550
Pubmed

Sequence and expression of a novel murine interferon alpha gene--homology with enhancer elements in the regulatory region of the gene.

IFNA7 IFNA10

3.15e-04127723017340
Pubmed

Mapping of murine interferon-alpha genes to chromosome 4.

IFNA7 IFNA10

3.15e-04127726689487
Pubmed

Regulation of effector and memory T-cell functions by type I interferon.

IFNA7 IFNA10

3.15e-041277221320124
Pubmed

MAVS Deficiency Is Associated With a Reduced T Cell Response Upon Secondary RSV Infection in Mice.

IFNA7 IFNA10

3.15e-041277233123150
Pubmed

Interferon-alpha/beta genes are up-regulated in murine brain astrocytes after infection with Theiler's murine encephalomyelitis virus.

IFNA7 IFNA10

3.15e-041277220038206
Pubmed

Interferon-alpha initiates type 1 diabetes in nonobese diabetic mice.

IFNA7 IFNA10

3.15e-041277218716002
Pubmed

Murine alpha/beta interferons inhibit benzo(a)pyrene activation and mutagenesis in mice.

IFNA7 IFNA10

3.15e-04127728304945
Pubmed

Characterization of murine interferon-alpha 12 (MuIFN-alpha12): biological activities and gene expression.

IFNA7 IFNA10

3.15e-041277217451966
Pubmed

The virus-induced factor VIF differentially recognizes the virus-responsive modules of the mouse IFNA4 gene promoter.

IFNA7 IFNA10

3.15e-041277211846978
Pubmed

Alveolar macrophage-derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes.

IFNA7 IFNA10

3.15e-041277225897172
Pubmed

A novel anti-viral role for STAT3 in IFN-α signalling responses.

IFNA7 IFNA10

3.15e-041277227988795
Pubmed

Negative regulation of the alpha interferon-induced antiviral response by the Ras/Raf/MEK pathway.

IFNA7 IFNA10

3.15e-041277216611902
Pubmed

Obesity worsens the outcome of influenza virus infection associated with impaired type I interferon induction in mice.

IFNA7 IFNA10

3.15e-041277230967261
Pubmed

Identification of distal silencing elements in the murine interferon-A11 gene promoter.

IFNA7 IFNA10

3.15e-04127728760352
Pubmed

Evolution of the interferon alpha gene family in eutherian mammals.

IFNA7 IFNA10

3.15e-041277217512142
Pubmed

A polymorphic trinucleotide repeat sequence mapping to distal mouse chromosome 4.

IFNA7 IFNA10

3.15e-04127728672140
Pubmed

Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes.

IFNA7 IFNA10

3.15e-04127729425112
Pubmed

IFN-alpha-mediated suppression of low-affinity FC(epsilon) receptors on Peyer's patch lymphocytes and augmentation of soluble CD23: implications for IgE responses.

IFNA7 IFNA10

3.15e-04127728656058
Pubmed

Repression of the murine interferon alpha 11 gene: identification of negatively acting sequences.

IFNA7 IFNA10

3.15e-04127721886773
Pubmed

Interferon-alpha subtype 11 activates NK cells and enables control of retroviral infection.

IFNA7 IFNA10

3.15e-041277222912583
Pubmed

The antiviral cytokines IFN-α and IFN-β modulate parietal epithelial cells and promote podocyte loss: implications for IFN toxicity, viral glomerulonephritis, and glomerular regeneration.

IFNA7 IFNA10

3.15e-041277223747509
Pubmed

Antiviral and myocyte protective effects of murine interferon-beta and -{alpha}2 in coxsackievirus B3-induced myocarditis and epicarditis in Balb/c mice.

IFNA7 IFNA10

3.15e-041277217434974
Pubmed

Behavioral effects of mouse interferons-alpha and -gamma and human interferon-alpha in mice.

IFNA7 IFNA10

3.15e-04127721422836
Pubmed

Mutation of the IFNAR-1 receptor binding site of human IFN-alpha2 generates type I IFN competitive antagonists.

IFNA7 IFNA10

3.15e-041277218937499
Pubmed

The physical separation of Lps and Ifa loci in BXH recombinant inbred mice.

IFNA7 IFNA10

3.15e-04127722572648
Pubmed

Structure and expression of a new murine interferon-alpha gene: MuIFN-alpha I9.

IFNA7 IFNA10

3.15e-04127723758677
Pubmed

Developmental control of IFN-alpha expression in murine embryos.

IFNA7 IFNA10

3.15e-04127727925651
Pubmed

The role of type 1 interferons in coagulation induced by gram-negative bacteria.

IFNA7 IFNA10

3.15e-041277232016282
Pubmed

Role of interferons in the regulation of cell proliferation, differentiation, and development.

IFNA7 IFNA10

3.15e-04127727530016
Pubmed

Interferon-alpha/beta can impede development of carcinogen-induced squamous-cell tumors in the esophagus of C57B1 mice.

IFNA7 IFNA10

3.15e-04127727601556
Pubmed

Suppression of the effector phase of inflammatory arthritis by double-stranded RNA is mediated by type I IFNs.

IFNA7 IFNA10

3.15e-041277217277125
Pubmed

Nonviral interferon alpha gene therapy inhibits growth of established tumors by eliciting a systemic immune response.

IFNA7 IFNA10

3.15e-04127729794206
Pubmed

Multiple pathways of interferon-induced gene expression in murine macrophages.

IFNA7 IFNA10

3.15e-04127727684767
Pubmed

Isolation and mapping of four new DNA markers from mouse chromosome 4.

IFNA7 IFNA10

3.15e-04127721360280
Pubmed

Structure and expression of cloned murine IFN-alpha genes.

IFNA7 IFNA10

3.15e-04127726188104
Pubmed

Ligation of CD180 inhibits IFN-α signaling in a Lyn-PI3K-BTK-dependent manner in B cells.

IFNA7 IFNA10

3.15e-041277226277892
Pubmed

Changes in expression of C2cd4c in pancreatic endocrine cells during pancreatic development.

C2CD4B C2CD4A

3.15e-041277227349930
Pubmed

GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on type I interferon signaling.

IFNA7 IFNA10

3.15e-041277219406830
Pubmed

Mapping the genetic region coding for herpes simplex virus resistance to mouse interferon alpha/beta.

IFNA7 IFNA10

3.15e-04127728245849
Pubmed

Isolation and characterization of a functional murine interferon alpha gene which is not expressed in fibroblasts upon virus induction.

IFNA7 IFNA10

3.71e-04137722471809
Pubmed

HIV-1 Gag-virus-like particles inhibit HIV-1 replication in dendritic cells and T cells through IFN-α-dependent upregulation of APOBEC3G and 3F.

IFNA7 IFNA10

3.71e-041377222739040
Pubmed

IFN-α directly promotes programmed cell death-1 transcription and limits the duration of T cell-mediated immunity.

IFNA7 IFNA10

3.71e-041377221263073
Pubmed

Interferon alpha-mediated inhibition of human immunodeficiency virus type 1 provirus synthesis in T-cells.

IFNA7 IFNA10

3.71e-04137728438572
Pubmed

Interferon alpha promotes caspase-8 dependent ultraviolet light-mediated keratinocyte apoptosis via interferon regulatory factor 1.

IFNA7 IFNA10

3.71e-041377238660315
Pubmed

Interferon-alpha and -gamma differentially reduce rapid immature T-cell death by contact with HIV-1 carrier cell clones in vitro.

IFNA7 IFNA10

3.71e-04137729343822
Pubmed

Plasmacytoid dendritic cell-derived type I interferon is crucial for the adjuvant activity of Toll-like receptor 7 agonists.

IFNA7 IFNA10

3.71e-041377220065291
Pubmed

Characterization of interferon-alpha 13, a novel constitutive murine interferon-alpha subtype.

IFNA7 IFNA10

3.71e-041377212930842
Pubmed

Effects of IFN alpha on late stages of HIV-1 replication cycle.

IFNA7 IFNA10

3.71e-04137729865497
Pubmed

Cutting edge: IL-12 and type I IFN differentially program CD8 T cells for programmed death 1 re-expression levels and tumor control.

IFNA7 IFNA10

3.71e-041377223804712
Pubmed

Obstruction of HIV-1 particle release by interferon-alpha occurs before viral protease processing and is independent of envelope glycoprotein.

IFNA7 IFNA10

3.71e-04137729181467
Pubmed

Evidence for a different susceptibility of primate lentiviruses to type I interferons.

IFNA7 IFNA10

3.71e-041377223255800
Pubmed

Spontaneous mutation of the Dock2 gene in Irf5-/- mice complicates interpretation of type I interferon production and antibody responses.

IFNA7 IFNA10

3.71e-041377222431588
Pubmed

Alveolar macrophages are the primary interferon-alpha producer in pulmonary infection with RNA viruses.

IFNA7 IFNA10

3.71e-041377217723216
Pubmed

Mouse interferon alpha and beta genes are linked at the centromere proximal region of chromosome 4.

IFNA7 IFNA10

3.71e-04137723973562
Pubmed

Effect of mutations affecting the p6 gag protein on human immunodeficiency virus particle release.

IFNA7 IFNA10

3.71e-04137722014240
Pubmed

Distinction of mouse interferon-alpha subtypes by polymerase chain reaction utilizing consensus primers and type-specific oligonucleotide probes.

IFNA7 IFNA10

3.71e-04137727523540
Pubmed

An interferon-alpha-induced tethering mechanism inhibits HIV-1 and Ebola virus particle release but is counteracted by the HIV-1 Vpu protein.

IFNA7 IFNA10

3.71e-041377218005734
Pubmed

Differential effect of murine alpha/beta interferon transgenes on antagonization of herpes simplex virus type 1 replication.

IFNA7 IFNA10

3.71e-041377212050368
Pubmed

Poly I:C-induced activation of NK cells by CD8 alpha+ dendritic cells via the IPS-1 and TRIF-dependent pathways.

IFNA7 IFNA10

3.71e-041377219635904
Pubmed

Murine coronavirus induces type I interferon in oligodendrocytes through recognition by RIG-I and MDA5.

IFNA7 IFNA10

3.71e-041377220427526
Pubmed

Sequencing and bacterial expression of a novel murine alpha interferon gene.

IFNA7 IFNA10

3.71e-041377218726328
InteractionTOP3B interactions

PCNX2 CDR2L TANC2 ZXDC ARAP3 KIAA0513 MYCBP2 PER1 NAV2 ZNF398 NLRC5 WDFY3 JADE1 ZNF839 PLXNB2 PLEKHG5 ABTB2 RAI1 TBCD ARAP1

3.34e-0714707620int:TOP3B
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

AFAP1 ARAP3 TIAM1 ARHGEF7 SKAP1 PLEKHA2 PLEKHG5 ARAP1

1.04e-07206518682
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZXDC SCRT2 ZBTB16 ZNF532 ZNF398 ZNF79 ZSCAN16 ZNF564 ZNF441

1.59e-0471851928
GeneFamilyInterferons

IFNA7 IFNA10

3.67e-0332512598
GeneFamilyArfGAPs

ARAP3 ARAP1

3.90e-0333512395
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

C2CD4B C2CD4A

4.62e-0336512823
GeneFamilyAnkyrin repeat domain containing

TANC2 ARAP3 ABTB2 ARAP1

4.78e-03242514403
CoexpressionONDER_CDH1_TARGETS_1_UP

ZBTB16 PAMR1 KCNMA1 PER1 DIDO1 TMEM214

2.98e-06139756M18757
CoexpressionMTOR_UP.N4.V1_DN

PCNX2 ZXDC ZBTB16 SLC41A3 ARID5B GALNT7

1.49e-05184756M2756
CoexpressionBENPORATH_ES_WITH_H3K27ME3

DUOX1 ZBTB16 GDF7 ARHGEF7 SKAP1 ARID5B KCNMA1 NAV2 CHAD C2CD4A PAX7 ARHGAP20 ABTB2

1.52e-0511157513M10371
CoexpressionGSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY3_UP

TIAM1 RPAIN MDH1 GALNT7 ABTB2 ARAP1

2.38e-05200756M8489
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

PCNX2 ZBTB16 GDF7 MYCBP2 SKAP1 KCNMA1 CHAD FGF12

3.62e-05438758M1954
CoexpressionMIKKELSEN_MCV6_HCP_WITH_H3K27ME3

PCNX2 ZBTB16 GDF7 MYCBP2 SKAP1 KCNMA1 CHAD FGF12

3.74e-05440758MM832
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

C2CD4B PAMR1 XIRP2 SKAP1 C2CD4A VWA5B1

5.00e-08115776207d464c09caf9be361daa56c83cd7da5cf9ce47
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-8|TCGA-Bladder / Sample_Type by Project: Shred V9

TANC2 GDF7 ZNF398 CHAD ZSCAN16

6.27e-061507751aa9320d97ff10994ea024751790524fe133aba9
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ZBTB16 ARID5B NAV2 WDFY3 ABTB2

1.82e-051877757e376831a11ee72ed87abcdac631ca46ae29c250
ToppCellrenal_cortex_nuclei-Adult_normal_reference|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

ZBTB16 ARHGEF7 PER1 ABTB2 STPG2

1.92e-05189775a48df46274d51e84ffb40264646de7346104efb9
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF703 KIAA0513 KCNMA1 WDFY3 LYL1

2.23e-051957753a30479857fc2805df92655c9599389559b1995d
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB16 MYCBP2 KCNMA1 PAX7 ARHGAP20

2.23e-051957755c86fddd6d0530beecf45ea5ba6b823123847696
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHA2 GALNT7 PLXNB2 ABTB2 VWA5B1

2.23e-051957753d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCellmild-Non-classical_Monocyte|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ZNF703 KCNMA1 LYL1 PLXNB2 ARAP1

2.52e-05200775692b48da9fd56bafcb3c8b33b0fe369160881c45
ToppCellmild-Non-classical_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ZNF703 KCNMA1 LYL1 PLXNB2 ARAP1

2.52e-05200775334bab6bf93d455f3526e817ea5785d8b6ee531c
ToppCellASK454-Epithelial-Type_2|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

AFAP1 NAV2 ANO5 ZNF441

9.11e-05136774ff9a5e111993fdb3ac64c5ef269e3460ff994517
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Nkx6-1_(SN/VTA_(SNr))-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

DUOX1 GDF7 STPG2

9.46e-0551773d30bf5365731c927e8c7dadc3f0aa85e948a83b7
ToppCellSubstantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Nkx6-1_(SN/VTA_(SNr))|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

DUOX1 GDF7 STPG2

9.46e-05517731e60abb9f3de9691f8f96553cae716c08535ed15
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

C2CD4B SLC41A3 SKAP1 ARID5B

1.02e-041407749f105687f5749399fd76043fd85da58be30f2caf
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

C2CD4B SLC41A3 SKAP1 ARID5B

1.02e-04140774a3be1fb7d2eb44bc123456d03250502938d46d9d
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 ANO5 PAX7 TDRD12

1.05e-041417744aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 ANO5 PAX7 TDRD12

1.05e-04141774e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCellfacs-Heart-Unknown-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 ANO5 PAX7 TDRD12

1.08e-04142774759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCellControl-NK|World / Disease group and Cell class

TANC2 DUOX1 TIAM1 NAV2

1.11e-04143774fe08adc9472dfd4242497d6c614d0490713261da
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-NP|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PAMR1 SKAP1 ANO5 NXPH3

1.33e-041507742ba55e51877e2e749cccdae7df5d885dc55b2587
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Poorly_Differentiated_or_Epithelioid_Leiomyosarcoma|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

SLC41A3 C2CD4A EXOG MDH1

1.40e-041527746f9c343669883618cd9c1c8921a90c34d153f303
ToppCell367C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ARAP3 NAV2 PLEKHG5 TBCD

1.58e-04157774f511871e1a004c6e9af08ee325ab1bfc41807487
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue|TCGA-Bladder / Sample_Type by Project: Shred V9

ZBTB16 PAMR1 KCNMA1 ARHGAP20

1.70e-041607748a41e2c96e0e170ac35daf6c403bf961b8d7c30b
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

ARID5B NLRC5 ZNF839 ZNF564

1.70e-041607748aaf6ac4f33ea291387fdbf9ff1a91d559391774
ToppCellTCGA-Bladder-Solid_Tissue_Normal|TCGA-Bladder / Sample_Type by Project: Shred V9

ZBTB16 PAMR1 KCNMA1 ARHGAP20

1.70e-04160774d6678996e12eaf2b735f1dfae32418cb2fabf268
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue|TCGA-Bladder / Sample_Type by Project: Shred V9

ZBTB16 PAMR1 KCNMA1 ARHGAP20

1.70e-04160774c8dc575562b463fd30832d322c28006f18f7ab9c
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ZNF532 NLRC5 ZNF839 ZNF564

1.74e-041617742fe77af3b41e6eacb707a64feea18f9991618173
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCNX2 KCNMA1 CHAD NXPH3

2.01e-04167774743df5908c1ceb43b34b240d9f9649f30f4142fa
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCNX2 C2CD4B KCNMA1 FGF12

2.01e-04167774cf6206c506715cd846799c62cf7c06e3fa99f7af
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCNX2 KCNMA1 CHAD NXPH3

2.01e-041677741adb566f98af0109c8cc6e36033b89651e2c75e7
ToppCellfacs-Tongue-nan-3m-Epithelial-basal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCNX2 ZBTB16 ARID5B STPG2

2.05e-04168774ca0c4a819f9047fc40d224f7656fec60f6fa05d8
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCNX2 C2CD4B KCNMA1 FGF12

2.10e-0416977430141f76e9bfc2b4586429857c72dbc85ba65cc9
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nxph3|Hippocampus / BrainAtlas - Mouse McCarroll V32

PAMR1 SKAP1 NXPH3

2.13e-0467773b80bdd122a0284611161c40ec7a9c893dc8de4de
ToppCellfacs-Spleen-nan-24m-Lymphocytic-Cd3e_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C2CD4B TIAM1 SKAP1 NAV2

2.30e-04173774f2eeff86e7dc7f4e3c36f775777d56685d7096cf
ToppCellfacs-Spleen-nan-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C2CD4B TIAM1 SKAP1 NAV2

2.35e-04174774096bc6f1889f2bbadfe1e1a3eb6ae569aaa2ee7d
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C2CD4B MYCBP2 FGF12 WDFY3

2.45e-041767745e46a09a36b9645b1b1fcb0b64bd0898561af3a9
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C2CD4B MYCBP2 FGF12 WDFY3

2.50e-0417777414fb8d182775dfd0e49aa7e4e12543a85b3b8bd6
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-ILC2|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZBTB16 TIAM1 SKAP1 ZNF839

2.56e-041787745101a45595cd8d702f911afadf1eb0ee10bdcefc
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-Megakaryocyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIAA0513 XIRP2 NLRC5 LYL1

2.61e-041797748d9bad6507fac0926163807a0bda62a57e7660e3
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARID5B PLEKHA2 GALNT7 ABTB2

2.61e-04179774d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCellLV|World / Chamber and Cluster_Paper

XIRP2 FSD2 ANO5 FGF12

2.67e-041807745ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK7 PLEKHA2 FGF12 ABTB2

2.73e-04181774b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

CDR2L ARAP3 KIAA0513 PLEKHG5

2.78e-04182774fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCellfacs-Heart-LA-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDF7 FSD2 FGF12 MDH1

2.84e-04183774905e1e9be0f15be184447df04b134a6aa8279074
ToppCellfacs-Heart-LA-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GDF7 FSD2 FGF12 MDH1

2.84e-0418377492eed783347a372b850de3189e72525082390014
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C2CD4B TIAM1 SKAP1 NAV2

2.90e-041847748c23945bafe8926f25836bc208115edd5214a2b0
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP2 FSD2 FGF12 MDH1

2.96e-041857749ef66bf63ed728cbf3044520a2a1625a9d5863a4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 SKAP1 ABTB2 VWA5B1

2.96e-041857743d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP2 FSD2 FGF12 MDH1

2.96e-041857742148b78db2afaf29b01d604d314d6061179e2663
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 SKAP1 KCNMA1 NAV2

3.09e-0418777487b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

PCNX2 PAMR1 NAV2 ABTB2

3.09e-041877744ea486991f66c29728d127171a07b81404ec0b78
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 SKAP1 KCNMA1 NAV2

3.09e-0418777442a1267bfc27b4460b8409ada580a87c4385841c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 SKAP1 KCNMA1 NAV2

3.09e-0418777464afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 SKAP1 KCNMA1 ABTB2

3.09e-0418777477886f99c229610abd28c4c370d2c7d1536c9782
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

XIRP2 FSD2 ANO5 FGF12

3.09e-0418777478cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCellCOVID-19-kidney-CD-IC-B|kidney / Disease (COVID-19 only), tissue and cell type

TIAM1 SKAP1 GALNT7 VWA5B1

3.09e-04187774ce05b89860573fe0356102e2998d1ef6d1968034
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 DOCK7 FGF12 ABTB2

3.09e-04187774e3095455d2f255854f339f6b05fa87852af0700f
ToppCellICU-SEP-Lymphocyte-B-B_memory|ICU-SEP / Disease, Lineage and Cell Type

GDF7 ARID5B NAV2 CHAD

3.15e-04188774b6d81be72bbd72a68722ab51d1a72c436ef9bc17
ToppCellLV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

XIRP2 FSD2 ANO5 FGF12

3.15e-041887740758b474457efa36488e0195f7357100f4b6a090
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK7 FGF12 ABTB2 VWA5B1

3.15e-0418877458ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 PLEKHA2 FGF12 ABTB2

3.15e-04188774e30a4ddac0da8cdcf621d98e28e3895cd9307e7a
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

TFB1M KCNMA1 NAV2 STPG2

3.15e-04188774b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ODF2L TIAM1 SKAP1 ARID5B

3.21e-041897748130102c41b2978a8b83f765ce383f836a464795
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SKAP1 FGF12 ABTB2 VWA5B1

3.21e-04189774a9864873b19ab3e60acf11f288fa7275badc2e42
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK7 PLEKHA2 FGF12 ABTB2

3.21e-04189774c9565e962a13a7713056ec3dbb1b67d24f9889c7
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Myeloid-Dendritic|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK7 ZNF398 PLEKHG5 ARAP1

3.21e-04189774c2a936f1008d691dac900f033a8a0f425dcf310b
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Myeloid-Dendritic-conventional_dendritic_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK7 ZNF398 PLEKHG5 ARAP1

3.21e-041897742cb730488709bcb56ce3468f3d74366d8bce9c72
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK7 GALNT7 ABTB2 VWA5B1

3.21e-04189774532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 SKAP1 ARID5B NAV2

3.28e-04190774bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 SKAP1 ARID5B NAV2

3.28e-04190774b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCellFibroblasts-CD55+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

TIAM1 PLEKHA2 ANO5 GALNT7

3.28e-04190774b4088128f5acf53f43244c9af9fe44e033f1a57a
ToppCellT_cells-Effector_memory_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

PCNX2 ODF2L ZBTB16 KIAA0513

3.28e-0419077413dc3a0aaa554f63eabac37726bd1f11b66fb3dd
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 PLEKHA2 FGF12 ABTB2

3.28e-0419077411d3c31167ea71809b4cc3757a0c6ea54a448602
ToppCelltumor_Lung-T/NK_cells-Exhausted_Tfh|tumor_Lung / Location, Cell class and cell subclass

AFAP1 TIAM1 SKAP1 ARID5B

3.34e-041917743e259eba83f8159d1a1a96b98d0e867fe547c5e7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 SKAP1 ARID5B NAV2

3.34e-041917749032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PAMR1 KCNMA1 NAV2 ABTB2

3.34e-04191774b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 SKAP1 ARID5B NAV2

3.34e-041917745717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 PLEKHA2 FGF12 ABTB2

3.41e-04192774fd08ae787e936cfdb1ab8f19b0fd63005b462709
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB16 MYCBP2 KCNMA1 ARHGAP20

3.41e-0419277411088878043a6ff95ba1970361256a82e434b80a
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ODF2L TIAM1 SKAP1 ARID5B

3.41e-041927747ab626a516b07d899175ff12f1c8257688324e4b
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-CFuPNs|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

KCNMA1 MDH1 ARHGAP20 NXPH3

3.41e-04192774a8841ebd879f1c344ab4246fdef77044170f644d
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ZBTB16 ARID5B NAV2 ARAP1

3.41e-041927740afb9dbe468e0be442c326e11c5fc0f699b32f23
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF703 KCNMA1 LYL1 PLXNB2

3.41e-041927747bcdbd97fa8c3bfccde426d44979601226913fc3
ToppCellmild_COVID-19_(asymptomatic)-Non-classical_Monocyte|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

ZNF703 KCNMA1 PLXNB2 ARAP1

3.48e-041937747839040e703877ef321494ad8926a8604729ceda
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZBTB16 PAMR1 NAV2 JADE1

3.48e-04193774261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 C2CD4A TMEM214 GALNT7

3.55e-041947740797245ebfa389a6f66874cb0f11297f1456e600
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHA2 PLXNB2 ABTB2 VWA5B1

3.55e-041947744579b4a44f7c731553a284843c296866027d7c0e
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

ZBTB16 PAMR1 NAV2 ABTB2

3.55e-04194774234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 C2CD4A TMEM214 GALNT7

3.55e-041947740241b4b88d6210b4c1b8aa99db17115b18142f01
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

PCNX2 PAMR1 NAV2 ABTB2

3.62e-04195774a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCellsevere_COVID-19-Non-classical_Monocyte|World / disease group, cell group and cell class (v2)

ZNF703 KCNMA1 PLXNB2 ARAP1

3.62e-0419577472928a1d987a3a5361c666f3972292aefec5f548
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

ZBTB16 TIAM1 NAV2 ABTB2

3.62e-041957746a02ebbeb3199447ddce64d92d8809436e040eba
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

TANC2 ZNF532 SKAP1 NAV2

3.69e-0419677404f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCellsevere_COVID-19-Non-classical_Monocyte|severe_COVID-19 / disease group, cell group and cell class (v2)

ZNF703 KCNMA1 PLXNB2 ARAP1

3.69e-0419677434c1c74cad5e23196e86cfd6f19c836fe57b2264
ToppCellCOVID-19_Moderate-Non-classical_Monocyte|COVID-19_Moderate / disease group, cell group and cell class

ZNF703 KCNMA1 PLXNB2 ARAP1

3.69e-04196774256c557fa11414c9d2cbb1fcff33f482ee1c78ac
ToppCellCOVID-19_Severe-Non-classical_Monocyte|COVID-19_Severe / disease group, cell group and cell class

ZNF703 KCNMA1 PLXNB2 ARAP1

3.69e-04196774af9e8f5ef9d03862f707e105857309b55595b1b9
ToppCellremission-Non-classical_Monocyte|remission / disease stage, cell group and cell class

ZNF703 KCNMA1 LYL1 PLXNB2

3.69e-04196774049d995986c20ce066bd64fcc2d2f1c2f8899883
ToppCell(001)_CD16+_Monocyte|World / immune cells in Peripheral Blood (logTPM normalization)

ZNF703 KCNMA1 LYL1 PLXNB2

3.69e-0419677433843d550cbca03c044d593b1f6972e4d3871f7f
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF703 KCNMA1 LYL1 PLXNB2

3.69e-0419677429246378ffb1010fe6858da756ae3d13df2306ba
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Mesenchymal-skeletal_muscle_satellite_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 ZBTB16 ARID5B PAX7

3.69e-0419677497ac47daf5bb07fa5dda3976e1ae402750f959b5
ToppCellTransverse-T_cell-Treg|T_cell / Region, Cell class and subclass

GDF7 TIAM1 SKAP1 ARID5B

3.76e-04197774b7a1637e4baadd657f6279f4aa96cd590c9cd8c9
Diseasebrain disease (implicated_via_orthology)

TIAM1 MYCBP2

9.50e-056752DOID:936 (implicated_via_orthology)
Diseasecreatinine measurement

DUOX1 ZBTB16 ARID5B DOCK7 KCNMA1 FSD2 EXOG PRMT7 PLXNB2 TDRD12

2.07e-049957510EFO_0004518
Diseaserenal sinus adipose tissue measurement

TIAM1 ARHGAP20

4.88e-0413752EFO_0004864
Diseasemean fractional anisotropy measurement

WDFY3 STPG2 MOB2

1.85e-0395753EFO_0008399
Diseaseresponse to angiotensin-converting enzyme inhibitor, response to angiotensin receptor blocker, angioedema

KCNMA1 FGF12

1.99e-0326752EFO_0005325, EFO_0005532, EFO_0010735
Diseasecholesteryl esters to total lipids in large LDL percentage

DOCK7 NLRC5

2.83e-0331752EFO_0022249
Diseasefree cholesterol in small HDL measurement

DOCK7 NLRC5

3.59e-0335752EFO_0022270
Diseaseanti-GAD65 autoimmune neurological syndromes

NAV2 FGF12

3.59e-0335752EFO_0803379
DiseaseGrowth Disorders

KCNMA1 RAI1

3.80e-0336752C0018273
Diseasecholesteryl esters to total lipids in very large HDL percentage

DOCK7 NLRC5

3.80e-0336752EFO_0022257
Diseaseaortic measurement

AFAP1 GDF7 ARID5B PLEKHA2

3.87e-03251754EFO_0020865

Protein segments in the cluster

PeptideGeneStartEntry
TSPRCKDAFRLHSSS

CDR2L

166

Q86X02
ETKSRSFDLLTPHRC

ARAP3

446

Q8WWN8
NHTAPSEKRDFITCR

ANO5

791

Q75V66
FRHRTLENSPISSCD

AFAP1

671

Q8N556
FKELREERHCAPSGT

C1orf131

91

Q8NDD1
SVCARPSSHRIKSFD

ARHGEF7

141

Q14155
HIRDTDAFRSCKFPT

CHAD

336

O15335
PTCLKSSISCLRHRE

CC2D2B

886

Q6DHV5
ADVTCSLPRHLSTSK

ATG2B

1746

Q96BY7
RSIAASRFAPHLEKC

ATXN7L3

91

Q14CW9
CATSKAFPLETHRSR

NWD1

1376

Q149M9
SSCKRLRSDSRTPAF

RAI1

1581

Q7Z5J4
DLPRCTSESHLSCLK

ODF2L

26

Q9ULJ1
RLLKDGHCDRSTVPS

PAX7

136

P23759
FFDAVHCERTKRSPT

KIAA0513

311

O60268
FPSSFESLVRKICRH

MOB2

136

Q70IA6
PLKFSRTDHLASCLQ

DUOX1

411

Q9NRD9
RISPFSCLKDRHDFR

IFNA10

46

P01566
RDAHLSTPSQCTKRY

KCNMA1

1141

Q12791
CALLESPHTRRKESL

C2CD4B

101

A6NLJ0
SIPKENFSCLTRLDH

MDH1

146

P40925
DKRIFTTRHTPSCLF

PER1

356

O15534
HCARKRQEPSTTLDS

PCNX2

1606

A6NKB5
DACTRTEHKLSRDSP

PLXNB2

1721

O15031
RISPFSCLKDRHEFR

IFNA7

46

P01567
FPHLDRTSDIRNICS

EXOG

281

Q9Y2C4
KTLRLSECSFRPEHV

NLRC5

1326

Q86WI3
SECSFRPEHVSRLAT

NLRC5

1331

Q86WI3
ARSFRHCTASTLPKS

CKAP5

421

Q14008
LPVTCHRDSFSRMSL

DOCK7

2121

Q96N67
VSSSAACHSRRFEPL

PRMT7

256

Q9NVM4
RFHKPCRNDLESLLS

LINC00322

31

Q6ZN03
RFTHIPSGKCLDRSE

GALNT7

616

Q86SF2
SSVSKELCLIRFHPA

DIDO1

1111

Q9BTC0
RQKHFPERSCSFSSE

DENND4C

1036

Q5VZ89
SSRLKRRPSHCELDL

LYL1

126

P12980
EDRLCLPSSFHSRTC

KRTAP27-1

31

Q3LI81
CALLESPHTRRKESL

C2CD4A

106

Q8NCU7
LRHLESDRPEFKSCL

C14orf178

86

Q8N769
TCSHRLSTAFTKVLP

PAMR1

696

Q6UXH9
RRTSLCTHDPAKICS

NXPH3

186

O95157
SSPSKDGRSLCERHV

FGF12

31

P61328
HCSSPFSLVESRLKL

ARHGAP20

1121

Q9P2F6
KCHPRETSFSRSISL

PLEKHA2

301

Q9HB19
THRSLDSQLARKCPT

SCRT2

176

Q9NQ03
PSHSSELTEQKLRAC

RPAIN

161

Q86UA6
KPVTLHIDFCRDSTD

TDRD12

131

Q587J7
FDPRTLHSLAKSLCI

PPP1R42

136

Q7Z4L9
RELSPSDTHFTRCVA

FSD2

596

A1L4K1
RSRCSRKPLHVDFKE

GDF7

346

Q7Z4P5
LTHSCSRAFSSAPLK

FAM120AOS

156

Q5T036
FCRSTLPRKQDSDPH

NAV2

1491

Q8IVL1
YPVCHSKLDLERSSS

TANC2

1726

Q9HCD6
RPRQLSISHFKSLCD

TFB1M

291

Q8WVM0
RHKDSRYLTPLVCLS

SLC41A3

246

Q96GZ6
IKETRFSHPSLCLRS

MYCBP2

211

O75592
SCLLRKHVRAPEFAT

SLC25A52

106

Q3SY17
CSRHEDRKPSEVFRT

JADE1

36

Q6IE81
KPEHCFSSFRRLDAR

ABTB2

466

Q8N961
EKLSRSDPHRCSFSK

ARID5B

776

Q14865
SSPSTRRCHLEAKYR

ARAP1

631

Q96P48
PRICSETRSLSEHFS

XIRP2

3231

A4UGR9
KAFDCPSSVRTHERT

ZNF564

456

Q8TBZ8
RRHTDDPSKECFTLK

PLEKHG5

66

O94827
ACSHCPDSRRTFTKR

ZNF532

1086

Q9HCE3
PCDKRFATSEELLSH

ZNF703

466

Q9H7S9
KAFDSPSLCRRHETT

ZNF441

371

Q8N8Z8
EVCAERFPTHAKLSS

ZXDC

271

Q2QGD7
SECNRTFPSHTALKR

ZBTB16

521

Q05516
ESVSPTLRHCSKLFI

WDFY3

756

Q8IZQ1
RVFHLCCSSPESRKD

TIAM1

1371

Q13009
RKHASFLSATPRCLE

STPG2

381

Q8N412
DCPKRFADQARLTSH

ZNF398

431

Q8TD17
FLELLRSHQSRPAKC

TMEM214

241

Q6NUQ4
RHALFDLSSCSLRPK

ZNF839

181

A8K0R7
DSSSQKCSPHRRELY

ZSCAN16

26

Q9H4T2
LLCHRFPLIRKTTAS

TBCD

1116

Q9BTW9
EARPRKCETHTESFK

ZNF79

166

Q15937
PHLRRDSKKESCFEL

SKAP1

166

Q86WV1
TCHRVSLTTRPSESK

VWA5B1

1086

Q5TIE3